NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1022780750|gb|KZS24218|]
View 

type I-F CRISPR-associated protein Csy2 [Wohlfahrtiimonas chitiniclastica]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Csy2_I-F super family cl12127
CRISPR/Cas system-associated RAMP superfamily protein Csy2; CRISPR (Clustered Regularly ...
 1-127 2.85e-48

CRISPR/Cas system-associated RAMP superfamily protein Csy2; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog


The actual alignment was detected with superfamily member pfam09614:

Pssm-ID: 448412  Cd Length: 295  Bit Score: 156.23  E-value: 2.85e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1022780750   1 MLGNVLVEARDVMAKAMEE----NPEKDAITILLDHLAIQHEATPNEHNEGAQWSSARLGDHGWLVPISVGFQALSPVTD 76
Cdd:pfam09614 163 LPGFALVERRDLLAEHMEElqqtNPEADALDAWLDFSRLNHRAEVDEDGETVEWEYSPRPGRGWLVPIPVGYQALSPLYA 242

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1022780750  77 P--ILNQRDDVTPHCFAESILTLGRFVMPHRCESLSSLFWSYHVDEAQGLYLC 127
Cdd:pfam09614 243 PgeVANARDPSTPFRFVESVYSLGEWVSPHRLQDLDQLLWRYEYDPENGLYLC 295
 
Name Accession Description Interval E-value
Cas_Csy2 pfam09614
CRISPR-associated protein (Cas_Csy2); CRISPR (Clustered Regularly Interspaced Short ...
 1-127 2.85e-48

CRISPR-associated protein (Cas_Csy2); CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.


Pssm-ID: 430714  Cd Length: 295  Bit Score: 156.23  E-value: 2.85e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1022780750   1 MLGNVLVEARDVMAKAMEE----NPEKDAITILLDHLAIQHEATPNEHNEGAQWSSARLGDHGWLVPISVGFQALSPVTD 76
Cdd:pfam09614 163 LPGFALVERRDLLAEHMEElqqtNPEADALDAWLDFSRLNHRAEVDEDGETVEWEYSPRPGRGWLVPIPVGYQALSPLYA 242

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1022780750  77 P--ILNQRDDVTPHCFAESILTLGRFVMPHRCESLSSLFWSYHVDEAQGLYLC 127
Cdd:pfam09614 243 PgeVANARDPSTPFRFVESVYSLGEWVSPHRLQDLDQLLWRYEYDPENGLYLC 295
Csy2_I-F cd09736
CRISPR/Cas system-associated RAMP superfamily protein Csy2; CRISPR (Clustered Regularly ...
 1-128 5.50e-39

CRISPR/Cas system-associated RAMP superfamily protein Csy2; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog


Pssm-ID: 187867  Cd Length: 289  Bit Score: 132.44  E-value: 5.50e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1022780750   1 MLGNVLVEARDVMAKAMEE----NPEKDAITILLDHLAIQHEATPNEHNEGAQWSSARLGDhGWLVPISVGFQALSPVTD 76
Cdd:cd09736   157 LPGFALLDRSDLLAEALQRlqttNPEATLLDAWLDFAALNHQPLRDEEEAIESAYSRKKGN-GWLVPIPVGYQALSPLYD 235

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1022780750  77 P--ILNQRDDVTPHCFAESILTLGRFVMPHRCESLSSLFWSYHVDEAQGLYLCR 128
Cdd:cd09736   236 AgsVSNARDPETPHAFAESLYGLGEWVSPHRLTDLSQLLWRYHYDQEKGLYLCR 289
Cas5f COG5933
CRISPR-Cas system type I-F effector complex subunit Cas5f/Csy2, RAMP superfamily [Defense ...
 3-129 8.43e-35

CRISPR-Cas system type I-F effector complex subunit Cas5f/Csy2, RAMP superfamily [Defense mechanisms]; CRISPR-Cas system type I-F effector complex subunit Cas5f/Csy2, RAMP superfamily is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 444631  Cd Length: 319  Bit Score: 122.31  E-value: 8.43e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1022780750   3 GNVLVEARDVMA----KAMEENPEKDAITILLDHLAIQHEATPNEHNEGAQWSSARLGDHGWLVPISVGFQALSPVTDP- 77
Cdd:COG5933   173 GFALVDRSDLLAehlkELQQTNPEATLLDAWLDFSRLNHRPVPDDEKGKVKWEYVRKPGSGWLVPIPVGYQAISPLYPAg 252

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1022780750  78 -ILNQRDDVTPHCFAESILTLGRFVMPHRCESLSSLFWSYHVDEAQGLYLCRN 129
Cdd:COG5933   253 eVANARDPSTPFRFVESVYSLGEWISPHRLNDLEQLLWRYHSDPENGLYLCRN 305
cas_Csy2 TIGR02565
CRISPR type I-F/YPEST-associated protein Csy2; CRISPR (Clustered Regularly Interspaced Short ...
 1-128 8.96e-22

CRISPR type I-F/YPEST-associated protein Csy2; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.


Pssm-ID: 274204  Cd Length: 296  Bit Score: 87.58  E-value: 8.96e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1022780750   1 MLGNVLVEARDVMAKAMEE----NPEKDAITILLDHLAIQHEATPNEHNEGAQWSSARLGDHGWLVPISVGFQALSPVTD 76
Cdd:TIGR02565 163 LPGFALLDRQDLLAEHTQRlqqtNPQATALDAWLDFAALKHIPERAFSDETNWWTYSVKKGRGWLVPIPVGYQAISPLYA 242

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1022780750  77 P--ILNQRDDVTPHCFAESILTLGRFVMPHRC-ESLSSLFWSYHvDEAQGLYLCR 128
Cdd:TIGR02565 243 PgqVDNARDPHYPFQFVEALYSLGEWVFPHRIvDIDQLLWWTYY-DAQNDLYLCR 296
 
Name Accession Description Interval E-value
Cas_Csy2 pfam09614
CRISPR-associated protein (Cas_Csy2); CRISPR (Clustered Regularly Interspaced Short ...
 1-127 2.85e-48

CRISPR-associated protein (Cas_Csy2); CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.


Pssm-ID: 430714  Cd Length: 295  Bit Score: 156.23  E-value: 2.85e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1022780750   1 MLGNVLVEARDVMAKAMEE----NPEKDAITILLDHLAIQHEATPNEHNEGAQWSSARLGDHGWLVPISVGFQALSPVTD 76
Cdd:pfam09614 163 LPGFALVERRDLLAEHMEElqqtNPEADALDAWLDFSRLNHRAEVDEDGETVEWEYSPRPGRGWLVPIPVGYQALSPLYA 242

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1022780750  77 P--ILNQRDDVTPHCFAESILTLGRFVMPHRCESLSSLFWSYHVDEAQGLYLC 127
Cdd:pfam09614 243 PgeVANARDPSTPFRFVESVYSLGEWVSPHRLQDLDQLLWRYEYDPENGLYLC 295
Csy2_I-F cd09736
CRISPR/Cas system-associated RAMP superfamily protein Csy2; CRISPR (Clustered Regularly ...
 1-128 5.50e-39

CRISPR/Cas system-associated RAMP superfamily protein Csy2; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog


Pssm-ID: 187867  Cd Length: 289  Bit Score: 132.44  E-value: 5.50e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1022780750   1 MLGNVLVEARDVMAKAMEE----NPEKDAITILLDHLAIQHEATPNEHNEGAQWSSARLGDhGWLVPISVGFQALSPVTD 76
Cdd:cd09736   157 LPGFALLDRSDLLAEALQRlqttNPEATLLDAWLDFAALNHQPLRDEEEAIESAYSRKKGN-GWLVPIPVGYQALSPLYD 235

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1022780750  77 P--ILNQRDDVTPHCFAESILTLGRFVMPHRCESLSSLFWSYHVDEAQGLYLCR 128
Cdd:cd09736   236 AgsVSNARDPETPHAFAESLYGLGEWVSPHRLTDLSQLLWRYHYDQEKGLYLCR 289
Cas5f COG5933
CRISPR-Cas system type I-F effector complex subunit Cas5f/Csy2, RAMP superfamily [Defense ...
 3-129 8.43e-35

CRISPR-Cas system type I-F effector complex subunit Cas5f/Csy2, RAMP superfamily [Defense mechanisms]; CRISPR-Cas system type I-F effector complex subunit Cas5f/Csy2, RAMP superfamily is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 444631  Cd Length: 319  Bit Score: 122.31  E-value: 8.43e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1022780750   3 GNVLVEARDVMA----KAMEENPEKDAITILLDHLAIQHEATPNEHNEGAQWSSARLGDHGWLVPISVGFQALSPVTDP- 77
Cdd:COG5933   173 GFALVDRSDLLAehlkELQQTNPEATLLDAWLDFSRLNHRPVPDDEKGKVKWEYVRKPGSGWLVPIPVGYQAISPLYPAg 252

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1022780750  78 -ILNQRDDVTPHCFAESILTLGRFVMPHRCESLSSLFWSYHVDEAQGLYLCRN 129
Cdd:COG5933   253 eVANARDPSTPFRFVESVYSLGEWISPHRLNDLEQLLWRYHSDPENGLYLCRN 305
Csy2_I-F cd09676
CRISPR/Cas system-associated RAMP superfamily protein Csy2; CRISPR (Clustered Regularly ...
 1-128 9.50e-23

CRISPR/Cas system-associated RAMP superfamily protein Csy2; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog


Pssm-ID: 187807  Cd Length: 292  Bit Score: 90.22  E-value: 9.50e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1022780750   1 MLGNVLVEARDVMAKAMEE----NPEKDAITILLDHLAIQHEATPNEHNEGAQWSSARlGDHGWLVPISVGFQALSPVTD 76
Cdd:cd09676   161 LPGFALLDRQDLLAEHTQRlqqtNPQATALDAWLDFAALKHIPERAQSNDTVWSWSVK-KGRGWLVPIPVGYQAISPLYA 239

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1022780750  77 P--ILNQRDDVTPHCFAESILTLGRFVMPHRCESLSSLFWSYHvDEAQGLYLCR 128
Cdd:cd09676   240 PgqVDNARDPHYPFQFVEALYSLGEWVFPHRIVDIDQLLWYYH-DAQNDLYLCR 292
cas_Csy2 TIGR02565
CRISPR type I-F/YPEST-associated protein Csy2; CRISPR (Clustered Regularly Interspaced Short ...
 1-128 8.96e-22

CRISPR type I-F/YPEST-associated protein Csy2; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.


Pssm-ID: 274204  Cd Length: 296  Bit Score: 87.58  E-value: 8.96e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1022780750   1 MLGNVLVEARDVMAKAMEE----NPEKDAITILLDHLAIQHEATPNEHNEGAQWSSARLGDHGWLVPISVGFQALSPVTD 76
Cdd:TIGR02565 163 LPGFALLDRQDLLAEHTQRlqqtNPQATALDAWLDFAALKHIPERAFSDETNWWTYSVKKGRGWLVPIPVGYQAISPLYA 242

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1022780750  77 P--ILNQRDDVTPHCFAESILTLGRFVMPHRC-ESLSSLFWSYHvDEAQGLYLCR 128
Cdd:TIGR02565 243 PgqVDNARDPHYPFQFVEALYSLGEWVFPHRIvDIDQLLWWTYY-DAQNDLYLCR 296
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH