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DIS3-like exonuclease 1 isoform 4 [Homo sapiens]
Protein Classification
ribonuclease R family protein ( domain architecture ID 11426128 )
ribonuclease R (RNaseR or RNR) family protein similar to RNR, a 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
List of domain hits
Name
Accession
Description
Interval
E-value
RNB
pfam00773 RNB domain; This domain is the catalytic domain of ribonuclease II.
95-445
4.34e-104
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain]
Cd Length: 314
Bit Score: 319.61
E-value: 4.34e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 95 RKDLR KS h LVFS IDP KGCE D V DD TL SV RT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS 174
Cdd:pfam00773 1 RKDLR DL - PFIT IDP ADAK D L DD AI SV EK L P NG GYR LGVHIADV S H Y V P P G S PL D R EAR K R G T SV YL P DR VIP MLP EK LS 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 175 A DLCSL LG G V DR Y A V S IMWEL D K a SY E IKKVWYGRTI IRS AYK L F YE AAQE LL D G NLSVV D DIPEFK DL DE ksrqaklee 254
Cdd:pfam00773 80 N DLCSL NP G E DR L A L S VEITI D A - DG E VTSYEIYPSV IRS KAR L T YE EVDD LL E G KDAEK D KPDLAE DL RL --------- 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 255 lvwaigk L TDI A RHV RAKR DGC GAL E L EGV E VCVQ LD DKKN I h D LIPKQPLEV H ETVA E C M I LAN HW VA KKI w ESFPHQ A 334
Cdd:pfam00773 150 ------- L YEL A KIL RAKR LQR GAL D L DTP E NKLI LD EEGV I - D ILIQERTDA H SLIE E F M L LAN EA VA RHL - QELGIP A 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 335 L L R Q HP P P HQ E FFSE L RECAKAK gffidt RSN K T L AD SL DNAN D P hdpiv N RLL RSMATQA M SN A L Y FS tgscae E EFH H 414
Cdd:pfam00773 221 L Y R V HP E P DL E KLNS L IKLLQLL ------ PDD K G L SK SL EKIK D D ----- E RLL SILLLRT M PR A E Y SP ------ E PLG H 283
330 340 350
....*....|....*....|....*....|.
gi 1021589235 415 Y GL A LD K YTHFTSPIRRY S D IV VHR L L M A AI 445
Cdd:pfam00773 284 F GL G LD I YTHFTSPIRRY P D LI VHR Q L K A LL 314
OB_Dis3
pfam17849 Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 ...
17-62
5.45e-16
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 protein. This domain along with CSD1 binds to RNA.
Pssm-ID: 436091 [Multi-domain]
Cd Length: 77
Bit Score: 73.03
E-value: 5.45e-16
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1021589235 17 L QDFRV VV R ID S W EST S V YP N GH F V R VLG R IGD L E G E IAT IL V EN S 62
Cdd:pfam17849 32 L EGKLF VV K ID D W PEN S R YP L GH I V K VLG E IGD I E T E TEA IL L EN G 77
Rrp44_S1 super family
cl25439 S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases ...
511-586
1.18e-05
S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases such as yeast Rrp44.
pfam17215 :Pssm-ID: 435792
Cd Length: 87
Bit Score: 44.06
E-value: 1.18e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1021589235 511 Y S I RT -- NG VLL F I P R FGI K G AAY L KNKD G LVIS cgpdsc S E WKP gsl QRFQNKITSTTT d G ESV T FHL FD H V T VR IS 586
Cdd:pfam17215 6 Y V I KV fn NG IVV F V P K FGI E G LIR L EDLT G DEPE ------ A E FDA --- DEYSLTFPDKGS - G KKR T VGV FD K V R VR VK 73
Name
Accession
Description
Interval
E-value
RNB
pfam00773 RNB domain; This domain is the catalytic domain of ribonuclease II.
95-445
4.34e-104
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain]
Cd Length: 314
Bit Score: 319.61
E-value: 4.34e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 95 RKDLR KS h LVFS IDP KGCE D V DD TL SV RT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS 174
Cdd:pfam00773 1 RKDLR DL - PFIT IDP ADAK D L DD AI SV EK L P NG GYR LGVHIADV S H Y V P P G S PL D R EAR K R G T SV YL P DR VIP MLP EK LS 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 175 A DLCSL LG G V DR Y A V S IMWEL D K a SY E IKKVWYGRTI IRS AYK L F YE AAQE LL D G NLSVV D DIPEFK DL DE ksrqaklee 254
Cdd:pfam00773 80 N DLCSL NP G E DR L A L S VEITI D A - DG E VTSYEIYPSV IRS KAR L T YE EVDD LL E G KDAEK D KPDLAE DL RL --------- 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 255 lvwaigk L TDI A RHV RAKR DGC GAL E L EGV E VCVQ LD DKKN I h D LIPKQPLEV H ETVA E C M I LAN HW VA KKI w ESFPHQ A 334
Cdd:pfam00773 150 ------- L YEL A KIL RAKR LQR GAL D L DTP E NKLI LD EEGV I - D ILIQERTDA H SLIE E F M L LAN EA VA RHL - QELGIP A 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 335 L L R Q HP P P HQ E FFSE L RECAKAK gffidt RSN K T L AD SL DNAN D P hdpiv N RLL RSMATQA M SN A L Y FS tgscae E EFH H 414
Cdd:pfam00773 221 L Y R V HP E P DL E KLNS L IKLLQLL ------ PDD K G L SK SL EKIK D D ----- E RLL SILLLRT M PR A E Y SP ------ E PLG H 283
330 340 350
....*....|....*....|....*....|.
gi 1021589235 415 Y GL A LD K YTHFTSPIRRY S D IV VHR L L M A AI 445
Cdd:pfam00773 284 F GL G LD I YTHFTSPIRRY P D LI VHR Q L K A LL 314
VacB
COG0557 Exoribonuclease R [Transcription];
22-496
3.09e-103
Exoribonuclease R [Transcription];
Pssm-ID: 440323 [Multi-domain]
Cd Length: 711
Bit Score: 330.53
E-value: 3.09e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 22 VVV R I DSWESTSVY P N G HF V R VLG RI GD LEG EI ATILVENSISVI p F S E AQMC E mpvn TPES P WK V SPEEEQK R K DLR KS 101
Cdd:COG0557 177 VVV E I TRYPERRGP P E G RV V E VLG SP GD PGA EI LIAIRKHGLPHE - F P E EVLA E ---- AEAL P DE V PEADLKG R R DLR DL 251
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 102 H LV f S ID PKGCE D V DD TL S VRT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS AD LCSL L 181
Cdd:COG0557 252 P LV - T ID GEDAK D F DD AV S AEK L D NG GWR LGVHIADV S H Y V R P G S AL D R EAR K R G T SV YL P DR VIP MLP ER LS NG LCSL N 330
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 182 G G V DR Y A V S IMW E L D KAS y E IKKVWYG R TI IRS AYK L F YE AA Q EL LDG N lsvvddipefkdld EKSRQAKLEE LV WAIGK 261
Cdd:COG0557 331 P G E DR L A M S CEM E I D AKG - E VVSYEFY R SV IRS DAR L T YE EV Q AI LDG K -------------- DEELREEYAD LV PMLEE 395
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 262 L TDI A RHV R AK R DGC GA LELEGV E VCVQ LD DKKNIH D LI P KQPLEV H ETVA E C M I LAN HW VA KKI - WESF P hq A L L R Q H P 340
Cdd:COG0557 396 L YEL A KIL R KA R EKR GA IDFDLP E TKII LD EEGKPE D IV P RERNDA H KLIE E F M L LAN EA VA EFL e KLKL P -- F L Y R V H E 473
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 341 P P HQ E FFSE LRE CAKAK G FFI --- D TRSN K T L ADS L DNAND - P HDPIV N R - LLRSM A t QA M snal Y fstgsc AE E EFH H Y 415
Cdd:COG0557 474 E P DP E KLEA LRE FLANL G LKL kgg D EPTP K D L QKL L EQVKG r P EEELL N T l LLRSM K - QA V ---- Y ------ SP E NIG H F 542
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 416 GLAL DK YTHFTSPIRRY S D IV VHR L L M A AISKDKKMEIKGN L fs NKD LEE LCR H INNRNQA A QHSQKQSTE L FQCM Y F KD 495
Cdd:COG0557 543 GLAL EA YTHFTSPIRRY P D LL VHR A L K A YLEGKRSPGLQEY L -- EEE LEE IAE H CSETERR A DEAERDVVD L KKAE Y M KD 620
.
gi 1021589235 496 K 496
Cdd:COG0557 621 R 621
RNB
smart00955 This domain is the catalytic domain of ribonuclease II;
95-447
6.78e-99
This domain is the catalytic domain of ribonuclease II;
Pssm-ID: 214935 [Multi-domain]
Cd Length: 286
Bit Score: 304.96
E-value: 6.78e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 95 R K DLR k SHLV F S IDP KGCE D V DD TL SV RT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS 174
Cdd:smart00955 1 R V DLR - DLPL F T IDP EDAK D I DD AV SV EK L D NG GYR LGVHIADV S H Y V K P G S AL D R EAR K R G T SV YL P DR VIP MLP EE LS 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 175 AD LCSL LG G V DR Y A V S IMWE LD KASY EI KKVWYG R TI IRS AYK L F YE AAQEL L DG nlsvvddipefkdldeksrqaklee 254
Cdd:smart00955 80 NG LCSL NP G E DR L A L S VEMT LD ADGG EI LDYEFY R SV IRS KAR L T YE EVDAI L EK ------------------------- 134
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 255 lvwaigkltdiarhvrakrdgcgalelegvevc VQ LD DKKN I H D LI P KQPLEV H ET V A E C MILAN HW VA KKIWESFP h QA 334
Cdd:smart00955 135 --------------------------------- IV LD EEGK I E D IV P RERNDA H SL V E E F MILAN EA VA RFLAKNGI - PG 180
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 335 L L R Q H PP P HQ E FFS E - L R E CAKAK G FFI - DTRSN K T LA DS L DNAN D PHD piv N RLL RSMATQA M SN A L Y FSTG S caeeef 412
Cdd:smart00955 181 L Y R V H EG P DP E KLA E l L K E FLALL G LLL l GGDGP K A LA KL L EKIR D SPE --- E RLL ELLLLRS M PH A E Y SVDN S ------ 251
330 340 350
....*....|....*....|....*....|....*
gi 1021589235 413 H H Y GLALD K YTHFTSPIRRY S D IV VHR L L M AA ISK 447
Cdd:smart00955 252 G H F GLALD A YTHFTSPIRRY P D LI VHR Q L K AA LRG 286
RNase_R
TIGR02063 ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. ...
22-529
1.36e-91
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA]
Pssm-ID: 273947 [Multi-domain]
Cd Length: 709
Bit Score: 299.57
E-value: 1.36e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 22 V V V R I DSWESTSVYPN G HF V RV LG RIG D LEGE I AT I LVENS I s VIP F S E AQMC E mpvn TPES P WK V SP EE EQK RKDLR KS 101
Cdd:TIGR02063 178 V L V E I TKYPDRNRPAI G KV V EI LG HAD D PGID I LI I IRKHG I - PYE F P E EVLD E ---- AAKI P EE V PE EE IKG RKDLR DL 252
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 102 h LVFS ID PKGCE D V DD TLS V RT L NN GN LE LGV H IADV T H F V APN S YI D I EA RT R A T TY YL A DR RYD MLP SV LS ADL CSL L 181
Cdd:TIGR02063 253 - PFVT ID GEDAK D F DD AVY V EK L KD GN YK LGV A IADV S H Y V REG S AL D K EA LK R G T SV YL P DR VIP MLP ER LS NGI CSL N 331
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 182 GGV DR YAV S IMW E L DK ASYEI K KVW Y g RTI I R S AYK L F Y EAAQELLD G N lsvvddipef KD LD E K sr QAK L E E LVWAIGK 261
Cdd:TIGR02063 332 PNE DR LTL S CEM E I DK KGRVK K YEF Y - EAV I N S HAR L T Y NQVNDIIE G K ---------- DA LD K K -- EPP L K E MLKNLFE 398
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 262 L TD I A R HV R A KR dgc GA LELEGV E VCVQ LD DKKNIH D LI P KQPLEV H ETVA E C MI L AN HW VA KKI w E SFPHQALL R Q H PP 341
Cdd:TIGR02063 399 L YK I L R KK R K KR --- GA IDFDSK E AKII LD ENGKPI D IV P RERGDA H KLIE E F MI A AN ET VA EHL - E KAKLPFIY R V H ER 474
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 342 P HQ E ---- FFSE L RECA - KA KG FFI D TRSN K TLADS L - DNAND P HDPIV N R - LLRSM A t QA M snaly F S T gscae E EFH H 414
Cdd:TIGR02063 475 P SE E klqn LREF L KTLG i TL KG GTS D KPQP K DFQKL L e KVKGR P EEELI N T v LLRSM Q - QA K ----- Y S P ----- E NIG H 543
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 415 Y GLAL DK YTHFTSPIRRY S D IV VHRL LMA A ISKDKK - MEI K GNLFSNKD LEE LCR H INNRNQA A QHSQKQSTELFQCM Y F 493
Cdd:TIGR02063 544 F GLAL EY YTHFTSPIRRY P D LI VHRL IKK A LFGGEN t TTE K EREYLEAK LEE IAE H SSKTERR A DEAERDVNDWKKAE Y M 623
490 500 510
....*....|....*....|....*....|....*.
gi 1021589235 494 KD K dpate ERCISD GVI YSIRTN G VLLFIPRFG I K G 529
Cdd:TIGR02063 624 SE K ----- IGEEFE GVI SGVTSF G LFVELENNT I E G 654
PRK11642
PRK11642 ribonuclease R;
52-449
8.59e-33
ribonuclease R;
Pssm-ID: 236944 [Multi-domain]
Cd Length: 813
Bit Score: 135.26
E-value: 8.59e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 52 G E I ATI L VE N --- SIS V -------- IP FS ----- E A Q MCEMPVNT PE spwkvsp E EEQK R K DLR KSH LV f S ID PKGCE D V 115
Cdd:PRK11642 208 G K I VEV L GD N mgt GMA V dialrthe IP YI wpqav E Q Q VAGLKEEV PE ------- E AKAG R V DLR DLP LV - T ID GEDAR D F 279
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 116 DD TLSVRTLNN G NLE L G V H IADV THF V A P NSYI D I EAR T R A T TY Y LADRRYD MLP S VLS AD LCSL LGG VDR ------ YAV 189
Cdd:PRK11642 280 DD AVYCEKKRG G GWR L W V A IADV SYY V R P PTPL D R EAR N R G T SV Y FPSQVVP MLP E VLS NG LCSL NPQ VDR lcmvce MTI 359
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 190 S IMWE L dk AS Y E ikkvw YGRTIIR S AYK L F Y EAAQEL L D G NLSVVDDI - P EF K D L D E ksrqak L EE L V waig K LT D I AR H 268
Cdd:PRK11642 360 S SKGR L -- TG Y K ----- FYEAVMS S HAR L T Y TKVWHI L Q G DQDLREQY a P LV K H L E E ------ L HN L Y ---- K VL D K AR E 422
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 269 V R akrdgc G ALEL E GV E VCVQLDDKKN I HDLIPK Q PLEV H ETVA ECMILAN HWV A KKI w E SFPHQ AL L R Q H PP P HQ E FFS 348
Cdd:PRK11642 423 E R ------ G GISF E SE E AKFIFNAERR I ERIEQT Q RNDA H KLIE ECMILAN ISA A RFV - E KAKEP AL F R I H DK P ST E AIT 495
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 349 EL R ECAKAK G FFI --- DTRSNKTL A DS L DNAN D PH D piv NRL L RS M ATQA M SN A L Y fstgsc AE E EFH H Y GLAL DK Y T HF 425
Cdd:PRK11642 496 SF R SVLAEL G LEL pgg NKPEPRDY A EL L ESVA D RP D --- AEM L QT M LLRS M KQ A I Y ------ DP E NRG H F GLAL QS Y A HF 566
410 420
....*....|....*....|....
gi 1021589235 426 TSPIRRY S D IVV HR LLMAAIS K DK 449
Cdd:PRK11642 567 TSPIRRY P D LSL HR AIKYLLA K EQ 590
OB_Dis3
pfam17849 Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 ...
17-62
5.45e-16
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 protein. This domain along with CSD1 binds to RNA.
Pssm-ID: 436091 [Multi-domain]
Cd Length: 77
Bit Score: 73.03
E-value: 5.45e-16
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1021589235 17 L QDFRV VV R ID S W EST S V YP N GH F V R VLG R IGD L E G E IAT IL V EN S 62
Cdd:pfam17849 32 L EGKLF VV K ID D W PEN S R YP L GH I V K VLG E IGD I E T E TEA IL L EN G 77
Rrp44_S1
pfam17215 S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases ...
511-586
1.18e-05
S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases such as yeast Rrp44.
Pssm-ID: 435792
Cd Length: 87
Bit Score: 44.06
E-value: 1.18e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1021589235 511 Y S I RT -- NG VLL F I P R FGI K G AAY L KNKD G LVIS cgpdsc S E WKP gsl QRFQNKITSTTT d G ESV T FHL FD H V T VR IS 586
Cdd:pfam17215 6 Y V I KV fn NG IVV F V P K FGI E G LIR L EDLT G DEPE ------ A E FDA --- DEYSLTFPDKGS - G KKR T VGV FD K V R VR VK 73
Name
Accession
Description
Interval
E-value
RNB
pfam00773 RNB domain; This domain is the catalytic domain of ribonuclease II.
95-445
4.34e-104
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain]
Cd Length: 314
Bit Score: 319.61
E-value: 4.34e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 95 RKDLR KS h LVFS IDP KGCE D V DD TL SV RT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS 174
Cdd:pfam00773 1 RKDLR DL - PFIT IDP ADAK D L DD AI SV EK L P NG GYR LGVHIADV S H Y V P P G S PL D R EAR K R G T SV YL P DR VIP MLP EK LS 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 175 A DLCSL LG G V DR Y A V S IMWEL D K a SY E IKKVWYGRTI IRS AYK L F YE AAQE LL D G NLSVV D DIPEFK DL DE ksrqaklee 254
Cdd:pfam00773 80 N DLCSL NP G E DR L A L S VEITI D A - DG E VTSYEIYPSV IRS KAR L T YE EVDD LL E G KDAEK D KPDLAE DL RL --------- 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 255 lvwaigk L TDI A RHV RAKR DGC GAL E L EGV E VCVQ LD DKKN I h D LIPKQPLEV H ETVA E C M I LAN HW VA KKI w ESFPHQ A 334
Cdd:pfam00773 150 ------- L YEL A KIL RAKR LQR GAL D L DTP E NKLI LD EEGV I - D ILIQERTDA H SLIE E F M L LAN EA VA RHL - QELGIP A 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 335 L L R Q HP P P HQ E FFSE L RECAKAK gffidt RSN K T L AD SL DNAN D P hdpiv N RLL RSMATQA M SN A L Y FS tgscae E EFH H 414
Cdd:pfam00773 221 L Y R V HP E P DL E KLNS L IKLLQLL ------ PDD K G L SK SL EKIK D D ----- E RLL SILLLRT M PR A E Y SP ------ E PLG H 283
330 340 350
....*....|....*....|....*....|.
gi 1021589235 415 Y GL A LD K YTHFTSPIRRY S D IV VHR L L M A AI 445
Cdd:pfam00773 284 F GL G LD I YTHFTSPIRRY P D LI VHR Q L K A LL 314
VacB
COG0557 Exoribonuclease R [Transcription];
22-496
3.09e-103
Exoribonuclease R [Transcription];
Pssm-ID: 440323 [Multi-domain]
Cd Length: 711
Bit Score: 330.53
E-value: 3.09e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 22 VVV R I DSWESTSVY P N G HF V R VLG RI GD LEG EI ATILVENSISVI p F S E AQMC E mpvn TPES P WK V SPEEEQK R K DLR KS 101
Cdd:COG0557 177 VVV E I TRYPERRGP P E G RV V E VLG SP GD PGA EI LIAIRKHGLPHE - F P E EVLA E ---- AEAL P DE V PEADLKG R R DLR DL 251
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 102 H LV f S ID PKGCE D V DD TL S VRT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS AD LCSL L 181
Cdd:COG0557 252 P LV - T ID GEDAK D F DD AV S AEK L D NG GWR LGVHIADV S H Y V R P G S AL D R EAR K R G T SV YL P DR VIP MLP ER LS NG LCSL N 330
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 182 G G V DR Y A V S IMW E L D KAS y E IKKVWYG R TI IRS AYK L F YE AA Q EL LDG N lsvvddipefkdld EKSRQAKLEE LV WAIGK 261
Cdd:COG0557 331 P G E DR L A M S CEM E I D AKG - E VVSYEFY R SV IRS DAR L T YE EV Q AI LDG K -------------- DEELREEYAD LV PMLEE 395
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 262 L TDI A RHV R AK R DGC GA LELEGV E VCVQ LD DKKNIH D LI P KQPLEV H ETVA E C M I LAN HW VA KKI - WESF P hq A L L R Q H P 340
Cdd:COG0557 396 L YEL A KIL R KA R EKR GA IDFDLP E TKII LD EEGKPE D IV P RERNDA H KLIE E F M L LAN EA VA EFL e KLKL P -- F L Y R V H E 473
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 341 P P HQ E FFSE LRE CAKAK G FFI --- D TRSN K T L ADS L DNAND - P HDPIV N R - LLRSM A t QA M snal Y fstgsc AE E EFH H Y 415
Cdd:COG0557 474 E P DP E KLEA LRE FLANL G LKL kgg D EPTP K D L QKL L EQVKG r P EEELL N T l LLRSM K - QA V ---- Y ------ SP E NIG H F 542
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 416 GLAL DK YTHFTSPIRRY S D IV VHR L L M A AISKDKKMEIKGN L fs NKD LEE LCR H INNRNQA A QHSQKQSTE L FQCM Y F KD 495
Cdd:COG0557 543 GLAL EA YTHFTSPIRRY P D LL VHR A L K A YLEGKRSPGLQEY L -- EEE LEE IAE H CSETERR A DEAERDVVD L KKAE Y M KD 620
.
gi 1021589235 496 K 496
Cdd:COG0557 621 R 621
RNB
smart00955 This domain is the catalytic domain of ribonuclease II;
95-447
6.78e-99
This domain is the catalytic domain of ribonuclease II;
Pssm-ID: 214935 [Multi-domain]
Cd Length: 286
Bit Score: 304.96
E-value: 6.78e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 95 R K DLR k SHLV F S IDP KGCE D V DD TL SV RT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS 174
Cdd:smart00955 1 R V DLR - DLPL F T IDP EDAK D I DD AV SV EK L D NG GYR LGVHIADV S H Y V K P G S AL D R EAR K R G T SV YL P DR VIP MLP EE LS 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 175 AD LCSL LG G V DR Y A V S IMWE LD KASY EI KKVWYG R TI IRS AYK L F YE AAQEL L DG nlsvvddipefkdldeksrqaklee 254
Cdd:smart00955 80 NG LCSL NP G E DR L A L S VEMT LD ADGG EI LDYEFY R SV IRS KAR L T YE EVDAI L EK ------------------------- 134
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 255 lvwaigkltdiarhvrakrdgcgalelegvevc VQ LD DKKN I H D LI P KQPLEV H ET V A E C MILAN HW VA KKIWESFP h QA 334
Cdd:smart00955 135 --------------------------------- IV LD EEGK I E D IV P RERNDA H SL V E E F MILAN EA VA RFLAKNGI - PG 180
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 335 L L R Q H PP P HQ E FFS E - L R E CAKAK G FFI - DTRSN K T LA DS L DNAN D PHD piv N RLL RSMATQA M SN A L Y FSTG S caeeef 412
Cdd:smart00955 181 L Y R V H EG P DP E KLA E l L K E FLALL G LLL l GGDGP K A LA KL L EKIR D SPE --- E RLL ELLLLRS M PH A E Y SVDN S ------ 251
330 340 350
....*....|....*....|....*....|....*
gi 1021589235 413 H H Y GLALD K YTHFTSPIRRY S D IV VHR L L M AA ISK 447
Cdd:smart00955 252 G H F GLALD A YTHFTSPIRRY P D LI VHR Q L K AA LRG 286
RNase_R
TIGR02063 ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. ...
22-529
1.36e-91
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA]
Pssm-ID: 273947 [Multi-domain]
Cd Length: 709
Bit Score: 299.57
E-value: 1.36e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 22 V V V R I DSWESTSVYPN G HF V RV LG RIG D LEGE I AT I LVENS I s VIP F S E AQMC E mpvn TPES P WK V SP EE EQK RKDLR KS 101
Cdd:TIGR02063 178 V L V E I TKYPDRNRPAI G KV V EI LG HAD D PGID I LI I IRKHG I - PYE F P E EVLD E ---- AAKI P EE V PE EE IKG RKDLR DL 252
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 102 h LVFS ID PKGCE D V DD TLS V RT L NN GN LE LGV H IADV T H F V APN S YI D I EA RT R A T TY YL A DR RYD MLP SV LS ADL CSL L 181
Cdd:TIGR02063 253 - PFVT ID GEDAK D F DD AVY V EK L KD GN YK LGV A IADV S H Y V REG S AL D K EA LK R G T SV YL P DR VIP MLP ER LS NGI CSL N 331
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 182 GGV DR YAV S IMW E L DK ASYEI K KVW Y g RTI I R S AYK L F Y EAAQELLD G N lsvvddipef KD LD E K sr QAK L E E LVWAIGK 261
Cdd:TIGR02063 332 PNE DR LTL S CEM E I DK KGRVK K YEF Y - EAV I N S HAR L T Y NQVNDIIE G K ---------- DA LD K K -- EPP L K E MLKNLFE 398
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 262 L TD I A R HV R A KR dgc GA LELEGV E VCVQ LD DKKNIH D LI P KQPLEV H ETVA E C MI L AN HW VA KKI w E SFPHQALL R Q H PP 341
Cdd:TIGR02063 399 L YK I L R KK R K KR --- GA IDFDSK E AKII LD ENGKPI D IV P RERGDA H KLIE E F MI A AN ET VA EHL - E KAKLPFIY R V H ER 474
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 342 P HQ E ---- FFSE L RECA - KA KG FFI D TRSN K TLADS L - DNAND P HDPIV N R - LLRSM A t QA M snaly F S T gscae E EFH H 414
Cdd:TIGR02063 475 P SE E klqn LREF L KTLG i TL KG GTS D KPQP K DFQKL L e KVKGR P EEELI N T v LLRSM Q - QA K ----- Y S P ----- E NIG H 543
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 415 Y GLAL DK YTHFTSPIRRY S D IV VHRL LMA A ISKDKK - MEI K GNLFSNKD LEE LCR H INNRNQA A QHSQKQSTELFQCM Y F 493
Cdd:TIGR02063 544 F GLAL EY YTHFTSPIRRY P D LI VHRL IKK A LFGGEN t TTE K EREYLEAK LEE IAE H SSKTERR A DEAERDVNDWKKAE Y M 623
490 500 510
....*....|....*....|....*....|....*.
gi 1021589235 494 KD K dpate ERCISD GVI YSIRTN G VLLFIPRFG I K G 529
Cdd:TIGR02063 624 SE K ----- IGEEFE GVI SGVTSF G LFVELENNT I E G 654
3_prime_RNase
TIGR00358 VacB and RNase II family 3'-5' exoribonucleases; This model is defined to identify a pair of ...
20-541
2.97e-60
VacB and RNase II family 3'-5' exoribonucleases; This model is defined to identify a pair of paralogous 3-prime exoribonucleases in E. coli, plus the set of proteins apparently orthologous to one or the other in other eubacteria. VacB was characterized originally as required for the expression of virulence genes, but is now recognized as the exoribonuclease RNase R (Rnr). Its paralog in E. coli and H. influenzae is designated exoribonuclease II (Rnb). Both are involved in the degradation of mRNA, and consequently have strong pleiotropic effects that may be difficult to disentangle. Both these proteins share domain-level similarity (RNB, S1) with a considerable number of other proteins, and full-length similarity scoring below the trusted cutoff to proteins associated with various phenotypes but uncertain biochemistry; it may be that these latter proteins are also 3-prime exoribonucleases. [Transcription, Degradation of RNA]
Pssm-ID: 273033 [Multi-domain]
Cd Length: 654
Bit Score: 213.81
E-value: 2.97e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 20 FR VVV RIDSWESTSVYPN G HFVRV LG RIG D LEGEIATI L VENS I SVIPFS -- E A Q MCEMPVNTP E SPW K V speeeqk R K D 97
Cdd:TIGR00358 124 DK VVV ELTEYPLRRNLFY G EITQI LG NND D PLIPWWVT L ARHE I PFEFPD gv E Q Q AAKLQFDVD E QAK K Y ------- R E D 196
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 98 L RKSHL V f S ID PKGCE D V DD TLS V RT L NN G NLE L G V H IADV THF VA P NS YI D I EA RT R ATTY YL ADRRYD MLP SV LS AD L 177
Cdd:TIGR00358 197 L TDLAF V - T ID GADAK D L DD AVY V KK L PD G GWK L Y V A IADV SYY VA E NS PL D K EA KH R GFSV YL PGFVIP MLP EE LS NG L 275
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 178 CSL LGGV DR YAVSIMWELD - KASYEIKKV w Y GR TI IRS A y K L F Y eaaqelldgnl SV V D D IP E FK D l DEKSRQAK L E E LV 256
Cdd:TIGR00358 276 CSL NPNE DR LVLVCEMTIS a QGRITDNEF - Y PA TI ESK A - R L T Y ----------- DK V N D WL E ND D - ELQPEYET L V E QL 341
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 257 W A IGK L TDIARHV R A KR dgc G ALEL E GV E VCVQL D DKKNIH D LIPKQPLEVHETVA E C MI L AN HWV A KKIWESFPH q ALL 336
Cdd:TIGR00358 342 K A LHQ L SQALGEW R H KR --- G LIDF E HP E TKFIV D EEGRVI D IVAEVRRIAEKIIE E A MI V AN ICA A RFLHNHKVP - GIY 417
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 337 R Q HP P P HQEFFSE L R E CAKAK G ----- FFIDTRSNKTL A DS L DNAN D -- PHDPI V N RLLRS matqa M S N A L Y FS tgscae 409
Cdd:TIGR00358 418 R V HP G P SKKKLQS L L E FLAEL G ltlpg GNAENVTTLDG A CW L REVK D rp EYEIL V T RLLRS ----- L S Q A E Y SP ------ 486
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 410 E EFH H Y GL A L DK Y T HFTSPIRRY S D IVV HRL LM A AIS K DKKME ik GNLFSNKD L EELCR H INNRNQA A QHSQKQSTELFQ 489
Cdd:TIGR00358 487 E PLG H F GL G L EH Y A HFTSPIRRY P D LTN HRL IK A VLA K EQTDT -- ERYQPQDE L LQIAE H CSDTERR A RDAERDVADWLK 564
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 1021589235 490 C M Y FK DK DPATEERC IS D ---- G VIYSIRT NG VLLF I PRFGIKGAA Y LKNKDGLVI 541
Cdd:TIGR00358 565 C R Y LL DK VGTEFSGE IS S vtrf G MFVRLDD NG IDGL I HISTLHNDY Y VFDQEKMAL 620
PRK11642
PRK11642 ribonuclease R;
52-449
8.59e-33
ribonuclease R;
Pssm-ID: 236944 [Multi-domain]
Cd Length: 813
Bit Score: 135.26
E-value: 8.59e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 52 G E I ATI L VE N --- SIS V -------- IP FS ----- E A Q MCEMPVNT PE spwkvsp E EEQK R K DLR KSH LV f S ID PKGCE D V 115
Cdd:PRK11642 208 G K I VEV L GD N mgt GMA V dialrthe IP YI wpqav E Q Q VAGLKEEV PE ------- E AKAG R V DLR DLP LV - T ID GEDAR D F 279
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 116 DD TLSVRTLNN G NLE L G V H IADV THF V A P NSYI D I EAR T R A T TY Y LADRRYD MLP S VLS AD LCSL LGG VDR ------ YAV 189
Cdd:PRK11642 280 DD AVYCEKKRG G GWR L W V A IADV SYY V R P PTPL D R EAR N R G T SV Y FPSQVVP MLP E VLS NG LCSL NPQ VDR lcmvce MTI 359
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 190 S IMWE L dk AS Y E ikkvw YGRTIIR S AYK L F Y EAAQEL L D G NLSVVDDI - P EF K D L D E ksrqak L EE L V waig K LT D I AR H 268
Cdd:PRK11642 360 S SKGR L -- TG Y K ----- FYEAVMS S HAR L T Y TKVWHI L Q G DQDLREQY a P LV K H L E E ------ L HN L Y ---- K VL D K AR E 422
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 269 V R akrdgc G ALEL E GV E VCVQLDDKKN I HDLIPK Q PLEV H ETVA ECMILAN HWV A KKI w E SFPHQ AL L R Q H PP P HQ E FFS 348
Cdd:PRK11642 423 E R ------ G GISF E SE E AKFIFNAERR I ERIEQT Q RNDA H KLIE ECMILAN ISA A RFV - E KAKEP AL F R I H DK P ST E AIT 495
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 349 EL R ECAKAK G FFI --- DTRSNKTL A DS L DNAN D PH D piv NRL L RS M ATQA M SN A L Y fstgsc AE E EFH H Y GLAL DK Y T HF 425
Cdd:PRK11642 496 SF R SVLAEL G LEL pgg NKPEPRDY A EL L ESVA D RP D --- AEM L QT M LLRS M KQ A I Y ------ DP E NRG H F GLAL QS Y A HF 566
410 420
....*....|....*....|....
gi 1021589235 426 TSPIRRY S D IVV HR LLMAAIS K DK 449
Cdd:PRK11642 567 TSPIRRY P D LSL HR AIKYLLA K EQ 590
Rnb
COG4776 Exoribonuclease II [Transcription];
90-586
3.52e-32
Exoribonuclease II [Transcription];
Pssm-ID: 443808 [Multi-domain]
Cd Length: 644
Bit Score: 132.67
E-value: 3.52e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 90 E E EQK R K DL rk SH L V F - S ID PKGC ED V DD T L SVRT L N NG NLE L G V H IAD V T HFVAPN S YI D I EAR T RA T T Y YL ADRRYD M 168
Cdd:COG4776 185 D E GLE R E DL -- TA L P F v T ID SEST ED M DD A L YIEK L E NG GWK L T V A IAD P T AYIPEG S EL D K EAR Q RA F T N YL PGFNIP M 262
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 169 LP SV LS A DLCSL LGGVD R Y A VSIMWEL D K ----- ASY E IKKV W ygrti IRS AY KL F Y EAAQEL L D G nls VVDDI PE FKDL 243
Cdd:COG4776 263 LP RE LS D DLCSL KENEK R P A LVCRVTI D A dgsig DDI E FFAA W ----- IRS KA KL A Y DNVSDW L E G --- KGEWQ PE NEEI 334
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 244 D E KS R Q akleelvwaigk L TDI A RHVRAK R DGCGALELEGVEVCVQ LD D K K N IH D LIPKQPLEVHET V A E C MI L AN HWV A 323
Cdd:COG4776 335 A E QI R L ------------ L HQF A LARSQW R QQHALVFKDRPDYRFE LD E K G N VL D IHAEPRRIANRI V E E A MI A AN ICA A 402
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 324 K kiwesfphqa L LR Q H P ----- PP H QE F FS E LR E C A KA ----------------- K GF ----- FI D TRSNKT L a DS ldna 376
Cdd:COG4776 403 R ---------- V LR E H L gfgif NV H SG F DP E KL E Q A VE llaehgiefdpeqlltl E GF calrr EL D AQPTSY L - DS ---- 467
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 377 ndphdpivn RL L R SMATQAM S N alyfstgscae E EFH H Y GL A LD K Y THF TSPIR R Y S D I V V HRL LM A A I SKDK kmeikgn 456
Cdd:COG4776 468 --------- RL R R FQTFAEI S T ----------- E PGP H F GL G LD A Y ATW TSPIR K Y G D M V N HRL IK A V I LGQP ------- 520
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 457 lf SN K DL EEL CRHINN R NQAAQHSQKQSTELFQCM Y F K D K dp ATEERCISDGV I YSI R T -------- NG VLL FIP rfgik 528
Cdd:COG4776 521 -- AE K PD EEL TERLAE R RRLNRMAERDVADWLYAR Y L K P K -- VGSGQVFTAEI I DIN R G glrvrlle NG AVA FIP ----- 591
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 1021589235 529 g A AYL - KNK D G LV I S cgpdscse WKP G SLQ rfqnkitstt TD GE s V TFH L F D HVT V RIS 586
Cdd:COG4776 592 - A SFI h SVR D E LV C S -------- QEE G TVY ---------- IK GE - V RYK L G D TIQ V TLA 630
PRK05054
PRK05054 exoribonuclease II; Provisional
90-542
2.09e-24
exoribonuclease II; Provisional
Pssm-ID: 179920 [Multi-domain]
Cd Length: 644
Bit Score: 108.43
E-value: 2.09e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 90 E E EQK R K DL rk SH L V F - S ID PKGC ED V DD T L S V RT L NN G N L E L G V H IAD V T HFV A PN S YI D IE AR T RA T T Y YL ADRRYD M 168
Cdd:PRK05054 185 D E GLE R E DL -- TA L D F v T ID SAST ED M DD A L Y V EK L PD G G L Q L T V A IAD P T AYI A EG S KL D KA AR Q RA F T N YL PGFNIP M 262
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 169 LP SV LS A DLCSL LGGVD R Y A VSIMWEL D KASYEIKKVWYGRTI I R S AY KL F Y EAAQEL L DGNLSVVDDIPEFK ---- D L D 244
Cdd:PRK05054 263 LP RE LS D DLCSL RPNER R P A LACRVTI D ADGTIEDDIRFFAAW I E S KA KL A Y DNVSDW L ENGGDWQPESEAIA eqir L L H 342
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 245 EKS r Q A KL E elv W aigkltdia R HVR A krdgcg ALELEGVEVCVQ L DD K KNIH D LIPKQPLEVHET V A E C MI L AN HWV A K 324
Cdd:PRK05054 343 QFC - L A RS E --- W --------- R KQH A ------ LVFKDRPDYRFE L GE K GEVL D IVAEPRRIANRI V E E S MI A AN ICA A R 403
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 325 kiwesfphqa L LR QH ppphqeffselrecaka K GF F I ------- D TRSNKTLADS L DNANDPH D P ---------- IVN R L 387
Cdd:PRK05054 404 ---------- V LR DK ----------------- L GF G I ynvhsgf D PANAEQAVAL L KEHGLHF D A eelltlegfc KLR R E 456
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 388 L RSMA T QAMSNAL -- YF S TGSCAE E EFH H Y GL A L DK Y THF TSPIR R Y S D IVV HRLL M A A I SKDKKMEIK gnlfsnkdl E E 465
Cdd:PRK05054 457 L DAQP T GYLDSRI rr FQ S FAEIST E PGP H F GL G L EA Y ATW TSPIR K Y G D MIN HRLL K A V I KGETAERPQ --------- D E 527
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021589235 466 LCRHINN R NQAAQHSQKQSTELFQCM Y F KDK d PA T EE R C --- I S D ---- G VIYSIRT NG VLL FIP rfgikg A AY L - KNK D 537
Cdd:PRK05054 528 ITVQLAE R RRLNRMAERDVGDWLYAR Y L KDK - AG T DT R F aae I I D isrg G MRVRLLE NG AVA FIP ------ A SF L h AVR D 600
....*
gi 1021589235 538 G LV IS 542
Cdd:PRK05054 601 E LV CN 605
OB_Dis3
pfam17849 Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 ...
17-62
5.45e-16
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 protein. This domain along with CSD1 binds to RNA.
Pssm-ID: 436091 [Multi-domain]
Cd Length: 77
Bit Score: 73.03
E-value: 5.45e-16
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1021589235 17 L QDFRV VV R ID S W EST S V YP N GH F V R VLG R IGD L E G E IAT IL V EN S 62
Cdd:pfam17849 32 L EGKLF VV K ID D W PEN S R YP L GH I V K VLG E IGD I E T E TEA IL L EN G 77
Rrp44_S1
pfam17215 S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases ...
511-586
1.18e-05
S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases such as yeast Rrp44.
Pssm-ID: 435792
Cd Length: 87
Bit Score: 44.06
E-value: 1.18e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1021589235 511 Y S I RT -- NG VLL F I P R FGI K G AAY L KNKD G LVIS cgpdsc S E WKP gsl QRFQNKITSTTT d G ESV T FHL FD H V T VR IS 586
Cdd:pfam17215 6 Y V I KV fn NG IVV F V P K FGI E G LIR L EDLT G DEPE ------ A E FDA --- DEYSLTFPDKGS - G KKR T VGV FD K V R VR VK 73
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
