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Conserved domains on  [gi|1020738684|ref|NP_001310298|]
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CCN family member 5 isoform 2 precursor [Homo sapiens]

Protein Classification

IGFBP domain-containing protein( domain architecture ID 10446222)

IGFBP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IGFBP pfam00219
Insulin-like growth factor binding protein;
45-78 4.99e-05

Insulin-like growth factor binding protein;


:

Pssm-ID: 459717  Cd Length: 53  Bit Score: 39.62  E-value: 4.99e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1020738684  45 LVLDGCGCCRVCARRLGEPCDQLH-VCDasQGLVC 78
Cdd:pfam00219  21 VVLDGCGCCKVCARQEGEPCGVYTpPCG--KGLRC 53
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
107-171 3.29e-03

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK14965:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 576  Bit Score: 38.18  E-value: 3.29e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1020738684 107 PLVSPAQNGA-RPGDPARPPVGWAWPPGCPTRTASADWRPSAACACPGPAHPPGVAVHKTVPSRAG 171
Cdd:PRK14965  382 PAPPSAAWGApTPAAPAAPPPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAASAG 447
 
Name Accession Description Interval E-value
IGFBP pfam00219
Insulin-like growth factor binding protein;
45-78 4.99e-05

Insulin-like growth factor binding protein;


Pssm-ID: 459717  Cd Length: 53  Bit Score: 39.62  E-value: 4.99e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1020738684  45 LVLDGCGCCRVCARRLGEPCDQLH-VCDasQGLVC 78
Cdd:pfam00219  21 VVLDGCGCCKVCARQEGEPCGVYTpPCG--KGLRC 53
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 107-171 3.29e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 38.18  E-value: 3.29e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1020738684 107 PLVSPAQNGA-RPGDPARPPVGWAWPPGCPTRTASADWRPSAACACPGPAHPPGVAVHKTVPSRAG 171
Cdd:PRK14965  382 PAPPSAAWGApTPAAPAAPPPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAASAG 447
IB smart00121
Insulin growth factor-binding protein homologues; High affinity binding partners of ...
 45-64 7.93e-03

Insulin growth factor-binding protein homologues; High affinity binding partners of insulin-like growth factors.


Pssm-ID: 197525  Cd Length: 75  Bit Score: 34.36  E-value: 7.93e-03
                           10        20
                   ....*....|....*....|
gi 1020738684   45 LVLDGCGCCRVCARRLGEPC 64
Cdd:smart00121  22 VRLDGCGCCPVCARQEGEPC 41
 
Name Accession Description Interval E-value
IGFBP pfam00219
Insulin-like growth factor binding protein;
45-78 4.99e-05

Insulin-like growth factor binding protein;


Pssm-ID: 459717  Cd Length: 53  Bit Score: 39.62  E-value: 4.99e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1020738684  45 LVLDGCGCCRVCARRLGEPCDQLH-VCDasQGLVC 78
Cdd:pfam00219  21 VVLDGCGCCKVCARQEGEPCGVYTpPCG--KGLRC 53
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 107-171 3.29e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 38.18  E-value: 3.29e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1020738684 107 PLVSPAQNGA-RPGDPARPPVGWAWPPGCPTRTASADWRPSAACACPGPAHPPGVAVHKTVPSRAG 171
Cdd:PRK14965  382 PAPPSAAWGApTPAAPAAPPPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAASAG 447
IB smart00121
Insulin growth factor-binding protein homologues; High affinity binding partners of ...
 45-64 7.93e-03

Insulin growth factor-binding protein homologues; High affinity binding partners of insulin-like growth factors.


Pssm-ID: 197525  Cd Length: 75  Bit Score: 34.36  E-value: 7.93e-03
                           10        20
                   ....*....|....*....|
gi 1020738684   45 LVLDGCGCCRVCARRLGEPC 64
Cdd:smart00121  22 VRLDGCGCCPVCARQEGEPC 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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