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Conserved domains on  [gi|1011057397|ref|YP_009239935|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Myzus persicae]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-312 1.86e-73

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 229.71  E-value: 1.86e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   1 MNLNLTKIMFFTLLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLLIFLINKNF 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  81 MFMNND---NMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYLNINKNMIFLIAL-ISMNSIF 156
Cdd:MTH00160   81 NLMLFNnisSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIIIILsAIIGAIG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 157 GLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFFKLNMLML-I 235
Cdd:MTH00160  161 GLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLnL 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1011057397 236 FSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFMLFNFNIFNKWYLQFKKNNYNFIMMM 312
Cdd:MTH00160  241 LSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNF 317
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-312 1.86e-73

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 229.71  E-value: 1.86e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   1 MNLNLTKIMFFTLLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLLIFLINKNF 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  81 MFMNND---NMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYLNINKNMIFLIAL-ISMNSIF 156
Cdd:MTH00160   81 NLMLFNnisSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIIIILsAIIGAIG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 157 GLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFFKLNMLML-I 235
Cdd:MTH00160  161 GLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLnL 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1011057397 236 FSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFMLFNFNIFNKWYLQFKKNNYNFIMMM 312
Cdd:MTH00160  241 LSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNF 317
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 10-289 5.65e-14

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 72.07  E-value: 5.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  10 FFTLLSFSTL---MSISASNWLSMWMGLELNLFSIIPILNF-KSSIYSIEATMKYFLIQAFASILLL------------- 72
Cdd:COG1007   104 FYALLLFATLgmmLMASANDLLTLFLGLELLSLSLYVLVAFrRDDRRSSEAALKYFLLGALSSGFLLygisllygatgsl 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  73 -IFLINKNFMFMNNDNMLIMMPLLM-------KLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMI---------S 135
Cdd:COG1007   184 nLAGIAAALAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 136 YLNINKNMIFLIALISM--NSIFGLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVN----YFLIYSMLN---FLIIkM 206
Cdd:COG1007   264 LAADWQLLLAVLAVLSMtvGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSaalfYLLAYLFMNlgaFAVI-L 342

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 207 LNNYNINYINQMK----FFNLNFFFKLNMLMLIFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIK 282
Cdd:COG1007   343 LLSRKGGEAEEIEdlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422


                  ....*..
gi 1011057397 283 MTYFMLF 289
Cdd:COG1007   423 VVKAMYF 429
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-273 1.16e-12

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 67.34  E-value: 1.16e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  24 ASNWLSMWMGLELNLFSIIPILNF-KSSIYSIEATMKYFLIQAFASILLL--------------IFLINKNFMFMNNDNM 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLfgislmynytgtlsFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  89 ------LIMMPLLMKLSLMPFHLWLPSMMEGLNW-FSCLLMMTWQKITPM-------IMISYLNINKNMIFLIALISM-- 152
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYglirrslLYLPSSPFIQQILLILAIISMll 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 153 NSIFGLNQNSMRKILAMSSINNSTWMLFAILM----NEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFFK 228
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1011057397 229 LN------MLMLIFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLT 273
Cdd:pfam00361 241 TMpilalvFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 10-290 7.85e-09

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 56.49  E-value: 7.85e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  10 FFTLLSFSTL---MSISASNWLSMWMGLEL-NLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLL------------- 72
Cdd:TIGR01770 104 FYILLLFALLgifLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLfgisliygftgsl 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  73 -IFLINKNFMFMNNDN-------MLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKIT---------PMIMIS 135
Cdd:TIGR01770 184 nFEDLLLFLSNGMLNIsllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifavflrlfLYILFG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 136 YLNINKNMIFLIALISM--NSIFGLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIY-------SMLNFLIIKM 206
Cdd:TIGR01770 264 FSEAWQIFLAIIAFLSMliGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYifiyalmSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 207 LNNYNINYINQMKFFNLNF----FFKLNMLMLIFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIK 282
Cdd:TIGR01770 344 LRSYKDEWIEYISDFAGLFktnpILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ....*...
gi 1011057397 283 MTYFMLFN 290
Cdd:TIGR01770 424 VVKVMYFD 431
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-312 1.86e-73

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 229.71  E-value: 1.86e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   1 MNLNLTKIMFFTLLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLLIFLINKNF 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  81 MFMNND---NMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYLNINKNMIFLIAL-ISMNSIF 156
Cdd:MTH00160   81 NLMLFNnisSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIIIILsAIIGAIG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 157 GLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFFKLNMLML-I 235
Cdd:MTH00160  161 GLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLnL 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1011057397 236 FSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFMLFNFNIFNKWYLQFKKNNYNFIMMM 312
Cdd:MTH00160  241 LSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNF 317
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 7-313 1.12e-43

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 152.73  E-value: 1.12e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   7 KIMFFTLLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLLI-FLINKNFMFMNN 85
Cdd:MTH00144    6 NLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFgSLIMYNLSFSWF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  86 DNMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYLNINKNMIFLIALIS-----MNSIFGLNQ 160
Cdd:MTH00144   86 SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISvlsalVGSIGGLNQ 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 161 NSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFFKLNMLMLIFSIMG 240
Cdd:MTH00144  166 TQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISLLLSLGG 245

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1011057397 241 LPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFMLFNFNIFNkwYLQFKKNNYNFIMMMN 313
Cdd:MTH00144  246 LPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSK--KSNSSKVLNSSIISLN 316
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 5-312 6.78e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 140.34  E-value: 6.78e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   5 LTKIMFFTLLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLL-------IFLIN 77
Cdd:MTH00112    4 HAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILfssttnaWNTGQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  78 KNFMFMNND--NMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIM--ISYLNINKNMIFLIALISM- 152
Cdd:MTH00112   84 WDITQLTNPtsCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLllMTSNSLNPTLLLTLAILSTl 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 153 -NSIFGLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFFKLNM 231
Cdd:MTH00112  164 iGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTT 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 232 LML-IFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFMLFNF-----NIFNKWYLQFKKNN 305
Cdd:MTH00112  244 LMLtLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLppnttNMMMKWRTKPKKNT 323


                  ....*..
gi 1011057397 306 YNFIMMM 312
Cdd:MTH00112  324 LTATLTT 330
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-285 5.15e-38

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 138.14  E-value: 5.15e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   1 MNLNLTKIMFFTLLSfSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLL------IF 74
Cdd:MTH00041    1 MNRNVLIFLITSIIL-GTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLngaliqAW 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  75 LINKNFMFMNNDNM---LIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYL--NINKNMIFLIAL 149
Cdd:MTH00041   80 LSGSWSINGPLNTLssiIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISIsnLLNSNILILCGI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 150 IS--MNSIFGLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFF 227
Cdd:MTH00041  160 LSvlVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPI 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1011057397 228 KLNMLML-IFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTY 285
Cdd:MTH00041  240 SAFLFILsILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISF 298
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-312 1.74e-36

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 133.64  E-value: 1.74e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   9 MFFTLLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLLI--FLINKNFMFMNND 86
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMggSLSFSNLYLSLLS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  87 NMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYLNINKNMIFLIALIS--MNSIFGLNQNSMR 164
Cdd:MTH00197   82 VVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSslIGGIGGMNQSNIR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 165 KILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFFKLNMLMLIF-SIMGLPP 243
Cdd:MTH00197  162 QLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFlSLGGLPP 241

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1011057397 244 MLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFMLFNFNIFNKWYLQFKKNNYNFIMMM 312
Cdd:MTH00197  242 LSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFILL 310
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 9-287 1.60e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 131.58  E-value: 1.60e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   9 MFFTLLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLLIFLINK---------N 79
Cdd:MTH00070    8 ILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINawftgewtiM 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  80 FMFMNNDNMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMI--SYLNINKNMIFLIALISM--NSI 155
Cdd:MTH00070   88 NMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLiqISHLLNSNLLIIMGLLSTliGGW 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 156 FGLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFFKLNMLMLI 235
Cdd:MTH00070  168 GGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLT 247

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1011057397 236 F-SIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFM 287
Cdd:MTH00070  248 LlSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAM 300
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-285 5.07e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 129.97  E-value: 5.07e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   1 MNLNLTKIMFFTLLSfSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLLIFLINKNF 80
Cdd:MTH00105    1 MNPLILIIIYLTLFL-GTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLM 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  81 M-----FMNNDN----MLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMIS--YLNINKNMIFLIAL 149
Cdd:MTH00105   80 YsgqwtITKLTNptasTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYqiSPSINPNLLLTLAI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 150 IS--MNSIFGLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFF 227
Cdd:MTH00105  160 LSilIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPL 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1011057397 228 KLNMLMLIF-SIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTY 285
Cdd:MTH00105  240 MTSLILLTLlSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIY 298
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 5-289 3.09e-32

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 122.77  E-value: 3.09e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   5 LTKIMFFTLLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLLIFLI-------- 76
Cdd:MTH00200    4 LILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLlnawtsgq 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  77 -NKNFMFMNNDNMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYLNINKNMIFLIALISMNSI 155
Cdd:MTH00200   84 wGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLSVL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 156 FG----LNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFFKLNM 231
Cdd:MTH00200  164 VGgwggLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSML 243

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1011057397 232 LMLIF-SIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFMLF 289
Cdd:MTH00200  244 LGLTLlSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLL 302
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-287 1.52e-29

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 115.29  E-value: 1.52e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   1 MNLNLTKIMFFTLlSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLLIFLI---- 76
Cdd:MTH00135    1 MNPYVLTILLFSL-GLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnaw 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  77 -----NKNFMFMNNDNMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMIsyLNINKNMIFLIALIS 151
Cdd:MTH00135   80 ltgqwDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALI--LQIAPTNPTLLITLG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 152 MNSIF-----GLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFF 226
Cdd:MTH00135  158 LTSTLvggwgGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAP 237

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1011057397 227 FKLNMLMLI-FSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFM 287
Cdd:MTH00135  238 ALTALTPLIlLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAM 299
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-283 3.71e-29

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 114.11  E-value: 3.71e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   6 TKIMFFTLLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLLIFLINKNF---MF 82
Cdd:MTH00011    7 TMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSfpsLL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  83 MNNDNMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYLNINKNMIFLIALISMNSIF----GL 158
Cdd:MTH00011   87 KNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAgglgGM 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 159 NQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLN-FFFKLNMLMLIFS 237
Cdd:MTH00011  167 NQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMsQTTSMSLFIMLLS 246

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1011057397 238 IMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKM 283
Cdd:MTH00011  247 LGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNL 292
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-294 4.41e-17

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 80.84  E-value: 4.41e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  13 LLSFSTLMSISASNWLSMWMGLELNLFSI-IPILNFKSSIYSIEATMKYFLIQAFASILLLI------------------ 73
Cdd:MTH00196    1 MVALGILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFgcallcgttgglhlsyin 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  74 FLINKNFMFMN----NDNMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYLNINKNMIFLIAL 149
Cdd:MTH00196   81 LVLNSGQSFSSvsvpIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 150 ISM--NSIFGLNQNSMRKILAMSSINNSTWMLFAILMNE-------KLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKF 220
Cdd:MTH00196  161 FSLfvGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiqasLVYLFIYIIMSICVFSIILALNVYKNLIIEFSGL 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1011057397 221 FNLNFFFKLNMLMLIFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFMLFNFNIF 294
Cdd:MTH00196  241 SRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIVKILFFQANSF 314
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-292 3.33e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 78.91  E-value: 3.33e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  13 LLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFK-SSIYSIEATMKYFLIQAFASILLLI-------------FLINK 78
Cdd:MTH00199  105 IVALGSLLLVSSINWLSIYLAIELQTLTLFILVALKrDSAYSTEAGLKYFVLGAVSSGLFLFgcallygltgetsIQGIN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  79 NFMFMNNDNMLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYLNINKNMIFLIALISM--NSIF 156
Cdd:MTH00199  185 SILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIiyGAIG 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 157 GLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIY-------SMLNFLIIKMLNNYNINYINQMKFFNLNFFFKL 229
Cdd:MTH00199  265 ALNQTKIKRLLAYSGIGHMGFILFGVAIGSFESIQASLIYmiiyvimSICSFSIILSLKLTKGLIVEVSGLSRKNPVIAL 344

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1011057397 230 NMLMLIFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFMLFNFN 292
Cdd:MTH00199  345 TLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVVQIIYFQAD 407
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 10-289 5.65e-14

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 72.07  E-value: 5.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  10 FFTLLSFSTL---MSISASNWLSMWMGLELNLFSIIPILNF-KSSIYSIEATMKYFLIQAFASILLL------------- 72
Cdd:COG1007   104 FYALLLFATLgmmLMASANDLLTLFLGLELLSLSLYVLVAFrRDDRRSSEAALKYFLLGALSSGFLLygisllygatgsl 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  73 -IFLINKNFMFMNNDNMLIMMPLLM-------KLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMI---------S 135
Cdd:COG1007   184 nLAGIAAALAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 136 YLNINKNMIFLIALISM--NSIFGLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVN----YFLIYSMLN---FLIIkM 206
Cdd:COG1007   264 LAADWQLLLAVLAVLSMtvGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSaalfYLLAYLFMNlgaFAVI-L 342

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 207 LNNYNINYINQMK----FFNLNFFFKLNMLMLIFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIK 282
Cdd:COG1007   343 LLSRKGGEAEEIEdlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422


                  ....*..
gi 1011057397 283 MTYFMLF 289
Cdd:COG1007   423 VVKAMYF 429
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-273 1.16e-12

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 67.34  E-value: 1.16e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  24 ASNWLSMWMGLELNLFSIIPILNF-KSSIYSIEATMKYFLIQAFASILLL--------------IFLINKNFMFMNNDNM 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLfgislmynytgtlsFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  89 ------LIMMPLLMKLSLMPFHLWLPSMMEGLNW-FSCLLMMTWQKITPM-------IMISYLNINKNMIFLIALISM-- 152
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYglirrslLYLPSSPFIQQILLILAIISMll 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 153 NSIFGLNQNSMRKILAMSSINNSTWMLFAILM----NEKLWVNYFLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFFK 228
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1011057397 229 LN------MLMLIFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLT 273
Cdd:pfam00361 241 TMpilalvFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
10-289 7.32e-12

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 65.61  E-value: 7.32e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  10 FFTLLSFSTL---MSISASNWLSMWMGLELN---LFSIIPILnfKSSIYSIEATMKYFLIQAFASILLLIFL-------- 75
Cdd:PRK05777  105 FYLLVLFALLgmmVMVSANDLLTLFLGLELLslpLYALAALR--RDRRRSLEAAIKYFVLGALASGFLLYGMsllygatg 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  76 ------INKNFMFMNNDNMLIMMPLLM-------KLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMI-------- 134
Cdd:PRK05777  183 slsfagIAKALADGSGNSLLLLFGLVFllvglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvaf 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 135 -SYLNINKNMIFLIALISM--NSIFGLNQNSMRKILAMSSINNSTWMLFAILMneklwVNYFLIYSMLNFLIIKMLNNYN 211
Cdd:PRK05777  263 gGLSEDWQQVLAIIAIASMlvGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAA-----GTAEGYSAVLFYLLAYLFMTLG 337

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 212 INYINQMKFFNLNF---------------FFKLNMLMLIFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILN 276
Cdd:PRK05777  338 AFGVISLLRRKGGEaesisdfaglskrspLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIG 417

                         330
                  ....*....|...
gi 1011057397 277 LFFYIKMTYFMLF 289
Cdd:PRK05777  418 AFYYLRVIKLMYF 430
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 10-290 7.85e-09

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 56.49  E-value: 7.85e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  10 FFTLLSFSTL---MSISASNWLSMWMGLEL-NLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLL------------- 72
Cdd:TIGR01770 104 FYILLLFALLgifLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLfgisliygftgsl 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  73 -IFLINKNFMFMNNDN-------MLIMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKIT---------PMIMIS 135
Cdd:TIGR01770 184 nFEDLLLFLSNGMLNIsllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifavflrlfLYILFG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 136 YLNINKNMIFLIALISM--NSIFGLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVNYFLIY-------SMLNFLIIKM 206
Cdd:TIGR01770 264 FSEAWQIFLAIIAFLSMliGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYifiyalmSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 207 LNNYNINYINQMKFFNLNF----FFKLNMLMLIFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIK 282
Cdd:TIGR01770 344 LRSYKDEWIEYISDFAGLFktnpILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ....*...
gi 1011057397 283 MTYFMLFN 290
Cdd:TIGR01770 424 VVKVMYFD 431
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 13-312 1.18e-08

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 55.26  E-value: 1.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  13 LLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIysieatMKYFLIQAFASILLLIFlinknfmfmnNDNMLIMM 92
Cdd:MTH00091    2 FLSLLNFMSLNIFVWWSVFLLMTLLFVFLNKGMGSYSSL------FNYFVLQESLGLLFLLF----------SFGYFQFL 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  93 PLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYLNINKNMIFLIALISMNSIFGLNQNSMRKILAMSSI 172
Cdd:MTH00091   66 ILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQMFLLKSYKNLLILSST 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 173 NNSTWMLFAilmneklwvnyfLIYSMLNFLIIKMLNNYNINYINQMKFFNLNFFFKLNMLMLIFsiMGLPPMLGFIMKWM 252
Cdd:MTH00091  146 ESFNWLILS------------FFFSFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFVSWETLLVF--MNLPFSVTFFVKIF 211

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 253 LIKTLIYNNMYFIMMMLIMLtilnLFFYIKMTYFMLFNFNIFNKWYLQFKKNNYNFIMMM 312
Cdd:MTH00091  212 SLSEILKVLGFFLLFLLFLM----FLSVLSLSFWLVNLSTKLFLMLFKYNKGFFFFFLPL 267
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 19-291 1.90e-08

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 55.64  E-value: 1.90e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  19 LMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSI---------EATMKYFLIQAFASILLLiFLINKNFMFMNNDNML 89
Cdd:MTH00198  202 LLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYL-FGCALYFGFTGNEGML 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  90 ------------------------IMMPLLMKLSLMPFHLWLPSMMEGLNWFSCLLMMTWQKITPMIMISYLNINKNMIF 145
Cdd:MTH00198  281 gtilsatlettnielrqgslgylfITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKLLL 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 146 LIALISM--NSIFGLNQNSMRKILAMSSINNSTWMLFAI-------LMNEKLWVNYFLIYSMLNFLIIKML--------- 207
Cdd:MTH00198  361 SVAIISLvvGAFGALNQTRIKRLLAYSGIGHIGFILIGVsagtyesLQASWTYAVTYLVSALASFTVICTLeefgtrtpt 440

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 208 ---------NNYNINYINQMKFFNLNFFFKLNMLMLIF-SIMGLPPMLGFIMKWML----IKTLIYNNM---YFIMMMLI 270
Cdd:MTH00198  441 srqrdgsfgNYNLVRRLVDLTILSRGQPYIAFSLAIVFlSLAGIPPLLGFLGKWFIlvgsIKIAFSSSLsiyYLVALFAI 520

                         330       340
                  ....*....|....*....|.
gi 1011057397 271 MLTILNLFFYIKMTYFMLFNF 291
Cdd:MTH00198  521 ICTCISAFYYIRIVATIYFNF 541
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 9-287 8.81e-06

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 47.06  E-value: 8.81e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397   9 MFFTLLSFSTLMSISASNWLSMWMGLELNLFSIIPILNFKSSIYSIEATMKYFLIQAFASILLL--IFLINKNFMFMNND 86
Cdd:COG0651   111 PLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLlgVGLLYGATGTLNMA 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397  87 NMLIMMP-----------------LLMKLSLMPFHLWLP-SMMEGLNWFSCLL------------MMTWQKITPMIMISY 136
Cdd:COG0651   191 DLAARLAeldpglllaafalllvgFGIKAALFPLHFWLPdAYPAAPSPVSALLsglltkvgvyaiLRVLTLLFGADPALF 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 137 LNInknMIFLIALISM--NSIFGLNQNSMRKILAMSSINNSTWMLFAILMNEKLWVN---YFLIYSMLN----FLIIKML 207
Cdd:COG0651   271 LGT---LLLVLGLLTMlvGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAgalFHLLNHALAkallFLAAGAI 347

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011057397 208 NNYNINYINQMKFFNLNFFFKLNMLMLI--FSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTY 285
Cdd:COG0651   348 ERATGTRDLDKLGGLGKRMPLTAAAFLIgaLALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFG 427


                  ..
gi 1011057397 286 FM 287
Cdd:COG0651   428 RA 429
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 233-289 2.80e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 39.09  E-value: 2.80e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1011057397 233 MLIFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTYFMLF 289
Cdd:PRK08375  374 VASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRAFF 430
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 232-285 7.54e-03

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 38.05  E-value: 7.54e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1011057397 232 LMLIFSIMGLPPMLGFIMKWMLIKTLIYNNMYFIMMMLIMLTILNLFFYIKMTY 285
Cdd:PRK08668  374 LVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLA 427
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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