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Conserved domains on  [gi|10092665|ref|NP_062547|]
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sushi domain-containing protein 2 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AMOP pfam03782
AMOP domain; This domain may have a role in cell adhesion. It is called the AMOP domain after ...
 289-429 3.14e-80

AMOP domain; This domain may have a role in cell adhesion. It is called the AMOP domain after Adhesion associated domain in MUC4 and Other Proteins. This domain is extracellular and contains a number of cysteines that probably form disulphide bridges.


:

Pssm-ID: 461048  Cd Length: 143  Bit Score: 254.21  E-value: 3.14e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665   289 ARTQCQAWEELEDQLPNFLEELPDCPCTLTQARADSGRFFTDYGCDMEQGSV--CTYHPGAVHCVRSVQASlRYGSGQQC 366
Cdd:pfam03782   1 AHDMCDNWYNCDRFLKNFLAELPSCPCTLPQALLDKGRFMPDPRCDLDWNPKetCTYHPGAVHCVRSGLPS-FSGSGQQC 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 10092665   367 CYTADGTQLLTADSSGGSTPDRGHDWGAPPFRTPPRVPSMSHWLYDVLSFYYCCLWAP-DCPRY 429
Cdd:pfam03782  80 CYDDDGYLMLTYDSFWGSTPDRGHDWGAPPYRSPPFVPGLSHWLHDVMPFYYCCLWADeDCERY 143
VWD super family cl47498
von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is ...
 448-613 4.80e-17

von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods.


The actual alignment was detected with superfamily member pfam00094:

Pssm-ID: 459671 [Multi-domain]  Cd Length: 154  Bit Score: 78.95  E-value: 4.80e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665   448 SAFGDPHFVTFDGTNFTFNGRGEYVLLEAA--LTDLRVQARAQPGTMSngteTRGTGLTAVAVQEGNSDVVEVRlanrtg 525
Cdd:pfam00094   2 SVSGDPHYVTFDGVKYTFPGTCTYVLAKDCseEPDFSFSVTNKNCNGG----ASGVCLKSVTVIVGDLEITLQK------ 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665   526 GLEVLLNQEVlsFTEQSWMDLKGMFLSVAAGDRVSIMLasgaGLEVSVQG-PFLSVSVLLPEKFLTHTHGLLGTLNNDPT 604
Cdd:pfam00094  72 GGTVLVNGQK--VSLPYKSDGGEVEILGSGFVVVDLSP----GVGLQVDGdGRGQLFVTLSPSYQGKTCGLCGNYNGNQE 145


                  ....*....
gi 10092665   605 DDFTLHSGR 613
Cdd:pfam00094 146 DDFMTPDGT 154
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 725-779 1.38e-14

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 68.64  E-value: 1.38e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 10092665 725 CGWLAPPPNGQKEG--NRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKCQ 779
Cdd:cd00033   1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
Somatomedin_B pfam01033
Somatomedin B domain;
29-64 2.71e-05

Somatomedin B domain;


:

Pssm-ID: 460034  Cd Length: 40  Bit Score: 41.91  E-value: 2.71e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 10092665    29 ESCSMRCGAL---DGPCSCHPTCSGLGTCCLDFRDFCLE 64
Cdd:pfam01033   1 ESCKGRCGESfdrGRLCQCDDDCVKYGDCCPDYESLCLG 39
 
Name Accession Description Interval E-value
AMOP pfam03782
AMOP domain; This domain may have a role in cell adhesion. It is called the AMOP domain after ...
 289-429 3.14e-80

AMOP domain; This domain may have a role in cell adhesion. It is called the AMOP domain after Adhesion associated domain in MUC4 and Other Proteins. This domain is extracellular and contains a number of cysteines that probably form disulphide bridges.


Pssm-ID: 461048  Cd Length: 143  Bit Score: 254.21  E-value: 3.14e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665   289 ARTQCQAWEELEDQLPNFLEELPDCPCTLTQARADSGRFFTDYGCDMEQGSV--CTYHPGAVHCVRSVQASlRYGSGQQC 366
Cdd:pfam03782   1 AHDMCDNWYNCDRFLKNFLAELPSCPCTLPQALLDKGRFMPDPRCDLDWNPKetCTYHPGAVHCVRSGLPS-FSGSGQQC 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 10092665   367 CYTADGTQLLTADSSGGSTPDRGHDWGAPPFRTPPRVPSMSHWLYDVLSFYYCCLWAP-DCPRY 429
Cdd:pfam03782  80 CYDDDGYLMLTYDSFWGSTPDRGHDWGAPPYRSPPFVPGLSHWLHDVMPFYYCCLWADeDCERY 143
AMOP smart00723
Adhesion-associated domain present in MUC4 and other proteins;
286-433 3.05e-62

Adhesion-associated domain present in MUC4 and other proteins;


Pssm-ID: 128962  Cd Length: 154  Bit Score: 206.29  E-value: 3.05e-62
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665    286 VAWARTQCQAWEELEDQLPNF---LEELPDCPCTLTQARADSGRFFTDYGCDMEQGSVCTYHPGAVHCVRSVQASLRYGS 362
Cdd:smart00723   2 RPWDRDMCLRWLECDGQLPNFlwdLEDLPSCPCSLPQAVADSGRFRPDDACDPDERILCTYHPGARHCIRSMQSVESTGA 81

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 10092665    363 GQQCCYTADGtQLLTADSSGGSTPDRGHDWGAPPFRTPPRVPSMSHWLYDVLSFYYCCLWAPD---CPRYMQRR 433
Cdd:smart00723  82 GQVCCYDAWG-QLMTTDDQPVIKPRRGHGAGTPPYIGSTEVPGLSHFKNDVEPYILCCKWADRpqrCTMYYWRR 154
VWD pfam00094
von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is ...
 448-613 4.80e-17

von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods.


Pssm-ID: 459671 [Multi-domain]  Cd Length: 154  Bit Score: 78.95  E-value: 4.80e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665   448 SAFGDPHFVTFDGTNFTFNGRGEYVLLEAA--LTDLRVQARAQPGTMSngteTRGTGLTAVAVQEGNSDVVEVRlanrtg 525
Cdd:pfam00094   2 SVSGDPHYVTFDGVKYTFPGTCTYVLAKDCseEPDFSFSVTNKNCNGG----ASGVCLKSVTVIVGDLEITLQK------ 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665   526 GLEVLLNQEVlsFTEQSWMDLKGMFLSVAAGDRVSIMLasgaGLEVSVQG-PFLSVSVLLPEKFLTHTHGLLGTLNNDPT 604
Cdd:pfam00094  72 GGTVLVNGQK--VSLPYKSDGGEVEILGSGFVVVDLSP----GVGLQVDGdGRGQLFVTLSPSYQGKTCGLCGNYNGNQE 145


                  ....*....
gi 10092665   605 DDFTLHSGR 613
Cdd:pfam00094 146 DDFMTPDGT 154
VWD smart00216
von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D ...
 447-612 4.01e-16

von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D domains: D1 and D2 are present within the N-terminal propeptide whereas the remaining D domains are required for multimerisation.


Pssm-ID: 214566 [Multi-domain]  Cd Length: 163  Bit Score: 76.67  E-value: 4.01e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665    447 ASAFGDPHFVTFDGTNFTFNGRGEYVLLEAA--LTDLRVQARaqpgtmSNGTETRGTGLTAVAVQEGNSDVVEVrlanrT 524
Cdd:smart00216  12 CSVSGDPHYTTFDGVAYTFPGNCYYVLAQDCssEPTFSVLLK------NVPCGGGATCLKSVKVELNGDEIELK-----D 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665    525 GGLEVLLNQE--VLSFTEqswmdlKGMFLSVAAGDRVSIMLASGAGLEVSVQGpFLSVSVLLPEKFLTHTHGLLGTLNND 602
Cdd:smart00216  81 DNGKVTVNGQqvSLPYKT------SDGSIQIRSSGGYLVVITSLGLIQVTFDG-LTLLSVQLPSKYRGKTCGLCGNFDGE 153

                          170
                   ....*....|
gi 10092665    603 PTDDFTLHSG 612
Cdd:smart00216 154 PEDDFRTPDG 163
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 725-779 1.38e-14

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 68.64  E-value: 1.38e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 10092665 725 CGWLAPPPNGQKEG--NRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKCQ 779
Cdd:cd00033   1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 725-778 1.60e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 62.93  E-value: 1.60e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 10092665    725 CGWLAPPPNGQKEG--NRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKC 778
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
725-778 4.99e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.66  E-value: 4.99e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 10092665   725 CGWLAPPPNG--QKEGNRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKC 778
Cdd:pfam00084   1 CPPPPDIPNGkvSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Somatomedin_B pfam01033
Somatomedin B domain;
29-64 2.71e-05

Somatomedin B domain;


Pssm-ID: 460034  Cd Length: 40  Bit Score: 41.91  E-value: 2.71e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 10092665    29 ESCSMRCGAL---DGPCSCHPTCSGLGTCCLDFRDFCLE 64
Cdd:pfam01033   1 ESCKGRCGESfdrGRLCQCDDDCVKYGDCCPDYESLCLG 39
SO smart00201
Somatomedin B -like domains; Somatomedin-B is a peptide, proteolytically excised from ...
 27-64 2.65e-04

Somatomedin B -like domains; Somatomedin-B is a peptide, proteolytically excised from vitronectin, that is a growth hormone-dependent serum factor with protease-inhibiting activity.


Pssm-ID: 197571  Cd Length: 43  Bit Score: 39.28  E-value: 2.65e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 10092665     27 AQESCSMRCGAL---DGPCSCHPTCSGLGTCCLDFRDFCLE 64
Cdd:smart00201   1 AIGSCKGRCGESfneGNACRCDALCLSYGDCCTDYESVCKK 41
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 720-778 9.47e-04

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 41.95  E-value: 9.47e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 10092665  720 QPVVSCGWLApppNGQKEGNRYlaGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKC 778
Cdd:PHA02927 208 HPTISNGYLS---SGFKRSYSY--NDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
 
Name Accession Description Interval E-value
AMOP pfam03782
AMOP domain; This domain may have a role in cell adhesion. It is called the AMOP domain after ...
 289-429 3.14e-80

AMOP domain; This domain may have a role in cell adhesion. It is called the AMOP domain after Adhesion associated domain in MUC4 and Other Proteins. This domain is extracellular and contains a number of cysteines that probably form disulphide bridges.


Pssm-ID: 461048  Cd Length: 143  Bit Score: 254.21  E-value: 3.14e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665   289 ARTQCQAWEELEDQLPNFLEELPDCPCTLTQARADSGRFFTDYGCDMEQGSV--CTYHPGAVHCVRSVQASlRYGSGQQC 366
Cdd:pfam03782   1 AHDMCDNWYNCDRFLKNFLAELPSCPCTLPQALLDKGRFMPDPRCDLDWNPKetCTYHPGAVHCVRSGLPS-FSGSGQQC 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 10092665   367 CYTADGTQLLTADSSGGSTPDRGHDWGAPPFRTPPRVPSMSHWLYDVLSFYYCCLWAP-DCPRY 429
Cdd:pfam03782  80 CYDDDGYLMLTYDSFWGSTPDRGHDWGAPPYRSPPFVPGLSHWLHDVMPFYYCCLWADeDCERY 143
AMOP smart00723
Adhesion-associated domain present in MUC4 and other proteins;
286-433 3.05e-62

Adhesion-associated domain present in MUC4 and other proteins;


Pssm-ID: 128962  Cd Length: 154  Bit Score: 206.29  E-value: 3.05e-62
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665    286 VAWARTQCQAWEELEDQLPNF---LEELPDCPCTLTQARADSGRFFTDYGCDMEQGSVCTYHPGAVHCVRSVQASLRYGS 362
Cdd:smart00723   2 RPWDRDMCLRWLECDGQLPNFlwdLEDLPSCPCSLPQAVADSGRFRPDDACDPDERILCTYHPGARHCIRSMQSVESTGA 81

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 10092665    363 GQQCCYTADGtQLLTADSSGGSTPDRGHDWGAPPFRTPPRVPSMSHWLYDVLSFYYCCLWAPD---CPRYMQRR 433
Cdd:smart00723  82 GQVCCYDAWG-QLMTTDDQPVIKPRRGHGAGTPPYIGSTEVPGLSHFKNDVEPYILCCKWADRpqrCTMYYWRR 154
VWD pfam00094
von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is ...
 448-613 4.80e-17

von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods.


Pssm-ID: 459671 [Multi-domain]  Cd Length: 154  Bit Score: 78.95  E-value: 4.80e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665   448 SAFGDPHFVTFDGTNFTFNGRGEYVLLEAA--LTDLRVQARAQPGTMSngteTRGTGLTAVAVQEGNSDVVEVRlanrtg 525
Cdd:pfam00094   2 SVSGDPHYVTFDGVKYTFPGTCTYVLAKDCseEPDFSFSVTNKNCNGG----ASGVCLKSVTVIVGDLEITLQK------ 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665   526 GLEVLLNQEVlsFTEQSWMDLKGMFLSVAAGDRVSIMLasgaGLEVSVQG-PFLSVSVLLPEKFLTHTHGLLGTLNNDPT 604
Cdd:pfam00094  72 GGTVLVNGQK--VSLPYKSDGGEVEILGSGFVVVDLSP----GVGLQVDGdGRGQLFVTLSPSYQGKTCGLCGNYNGNQE 145


                  ....*....
gi 10092665   605 DDFTLHSGR 613
Cdd:pfam00094 146 DDFMTPDGT 154
VWD smart00216
von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D ...
 447-612 4.01e-16

von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D domains: D1 and D2 are present within the N-terminal propeptide whereas the remaining D domains are required for multimerisation.


Pssm-ID: 214566 [Multi-domain]  Cd Length: 163  Bit Score: 76.67  E-value: 4.01e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665    447 ASAFGDPHFVTFDGTNFTFNGRGEYVLLEAA--LTDLRVQARaqpgtmSNGTETRGTGLTAVAVQEGNSDVVEVrlanrT 524
Cdd:smart00216  12 CSVSGDPHYTTFDGVAYTFPGNCYYVLAQDCssEPTFSVLLK------NVPCGGGATCLKSVKVELNGDEIELK-----D 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10092665    525 GGLEVLLNQE--VLSFTEqswmdlKGMFLSVAAGDRVSIMLASGAGLEVSVQGpFLSVSVLLPEKFLTHTHGLLGTLNND 602
Cdd:smart00216  81 DNGKVTVNGQqvSLPYKT------SDGSIQIRSSGGYLVVITSLGLIQVTFDG-LTLLSVQLPSKYRGKTCGLCGNFDGE 153

                          170
                   ....*....|
gi 10092665    603 PTDDFTLHSG 612
Cdd:smart00216 154 PEDDFRTPDG 163
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 725-779 1.38e-14

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 68.64  E-value: 1.38e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 10092665 725 CGWLAPPPNGQKEG--NRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKCQ 779
Cdd:cd00033   1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 725-778 1.60e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 62.93  E-value: 1.60e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 10092665    725 CGWLAPPPNGQKEG--NRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKC 778
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
725-778 4.99e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.66  E-value: 4.99e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 10092665   725 CGWLAPPPNG--QKEGNRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKC 778
Cdd:pfam00084   1 CPPPPDIPNGkvSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Somatomedin_B pfam01033
Somatomedin B domain;
29-64 2.71e-05

Somatomedin B domain;


Pssm-ID: 460034  Cd Length: 40  Bit Score: 41.91  E-value: 2.71e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 10092665    29 ESCSMRCGAL---DGPCSCHPTCSGLGTCCLDFRDFCLE 64
Cdd:pfam01033   1 ESCKGRCGESfdrGRLCQCDDDCVKYGDCCPDYESLCLG 39
SO smart00201
Somatomedin B -like domains; Somatomedin-B is a peptide, proteolytically excised from ...
 27-64 2.65e-04

Somatomedin B -like domains; Somatomedin-B is a peptide, proteolytically excised from vitronectin, that is a growth hormone-dependent serum factor with protease-inhibiting activity.


Pssm-ID: 197571  Cd Length: 43  Bit Score: 39.28  E-value: 2.65e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 10092665     27 AQESCSMRCGAL---DGPCSCHPTCSGLGTCCLDFRDFCLE 64
Cdd:smart00201   1 AIGSCKGRCGESfneGNACRCDALCLSYGDCCTDYESVCKK 41
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 720-778 9.47e-04

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 41.95  E-value: 9.47e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 10092665  720 QPVVSCGWLApppNGQKEGNRYlaGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKC 778
Cdd:PHA02927 208 HPTISNGYLS---SGFKRSYSY--NDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 729-779 2.91e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 40.41  E-value: 2.91e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 10092665  729 APPP--NGQKEG--NRYLAGSTIYFHCDNGYSLAGAETSTCQAdGTWSSPtPKCQ 779
Cdd:PHA02927 150 SPPSisNGRHNGyeDFYTDGSVVTYSCNSGYSLIGNSGVLCSG-GEWSDP-PTCQ 202
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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