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Conserved domains on  [gi|1004403746|gb|EFA11334|]
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hypothetical protein TcasGA2_TC010873 [Tribolium castaneum]

Protein Classification

MAP7 domain-containing protein( domain architecture ID 1001422)

MAP7 domain-containing protein such as MAP7D1 (microtubule-associated protein 7 domain containing 1) identified as a novel substrate of doublecortin-like kinase 1 (DCLK1)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MAP7 super family cl38194
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 414-502 1.96e-05

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


The actual alignment was detected with superfamily member pfam05672:

Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 45.03  E-value: 1.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1004403746 414 EAQRLAEQERLEEAIRETKRREEEERLRREEEQRSKLLKEEAERKAREEAEK---KFAEQQERLKNEEKEREARRKRVEA 490
Cdd:pfam05672  62 EARRLEEERRREEEERQRKAEEEAEEREQREQEEQERLQKQKEEAEAKAREEaerQRQEREKIMQQEEQERLERKKRIEE 141

                          90
                  ....*....|..
gi 1004403746 491 IMRRTRGVNNAN 502
Cdd:pfam05672 142 IMKRTRKSDQAE 153
 
Name Accession Description Interval E-value
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 414-502 1.96e-05

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 45.03  E-value: 1.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1004403746 414 EAQRLAEQERLEEAIRETKRREEEERLRREEEQRSKLLKEEAERKAREEAEK---KFAEQQERLKNEEKEREARRKRVEA 490
Cdd:pfam05672  62 EARRLEEERRREEEERQRKAEEEAEEREQREQEEQERLQKQKEEAEAKAREEaerQRQEREKIMQQEEQERLERKKRIEE 141

                          90
                  ....*....|..
gi 1004403746 491 IMRRTRGVNNAN 502
Cdd:pfam05672 142 IMKRTRKSDQAE 153
 
Name Accession Description Interval E-value
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 414-502 1.96e-05

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 45.03  E-value: 1.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1004403746 414 EAQRLAEQERLEEAIRETKRREEEERLRREEEQRSKLLKEEAERKAREEAEK---KFAEQQERLKNEEKEREARRKRVEA 490
Cdd:pfam05672  62 EARRLEEERRREEEERQRKAEEEAEEREQREQEEQERLQKQKEEAEAKAREEaerQRQEREKIMQQEEQERLERKKRIEE 141

                          90
                  ....*....|..
gi 1004403746 491 IMRRTRGVNNAN 502
Cdd:pfam05672 142 IMKRTRKSDQAE 153
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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