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Conserved domains on  [gi|1003779158|gb|AMO66377|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Doedicurus sp. FD-2016a]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 4.54e-62

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 189.24  E-value: 4.54e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158   1 MMYTVFLLSVVFVVSFIGFSSKPSPIYGGLGLIVGGGVGCGIVISLGGSFLGLMVFLVYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158  81 AWGSNIVILGGLFVGFLAEVVLIVWMMSDNGMGcVLCSLKDMEDWVVLGGNEVSLVREDFVGGSALYTYGSWLVVVAGWS 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVE-VVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....*
gi 1003779158 161 LFVTIFIVIEITRGR 175
Cdd:MTH00109  161 LFIGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 4.54e-62

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 189.24  E-value: 4.54e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158   1 MMYTVFLLSVVFVVSFIGFSSKPSPIYGGLGLIVGGGVGCGIVISLGGSFLGLMVFLVYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158  81 AWGSNIVILGGLFVGFLAEVVLIVWMMSDNGMGcVLCSLKDMEDWVVLGGNEVSLVREDFVGGSALYTYGSWLVVVAGWS 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVE-VVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....*
gi 1003779158 161 LFVTIFIVIEITRGR 175
Cdd:MTH00109  161 LFIGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
45-171 3.86e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.51  E-value: 3.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158  45 SLGGSFLGLMVFLVYLGGMLVVFGYTTAMATEEYPEAWGSNIVILGGLFVGFLAEVVLIVWMMSDNGMGcvlcslkDMED 124
Cdd:pfam00499  29 LLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGLLLLALLLLVLLSASLTP-------AAAA 101

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1003779158 125 WVVLGGNEVSLvredfvgGSALYTYGSWLVVVAGWSLFVTIFIVIEI 171
Cdd:pfam00499 102 AAPDVGNIEAI-------GELLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 4.54e-62

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 189.24  E-value: 4.54e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158   1 MMYTVFLLSVVFVVSFIGFSSKPSPIYGGLGLIVGGGVGCGIVISLGGSFLGLMVFLVYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158  81 AWGSNIVILGGLFVGFLAEVVLIVWMMSDNGMGcVLCSLKDMEDWVVLGGNEVSLVREDFVGGSALYTYGSWLVVVAGWS 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVE-VVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....*
gi 1003779158 161 LFVTIFIVIEITRGR 175
Cdd:MTH00109  161 LFIGVFVIIEITRGN 175
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 47-175 1.47e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 96.36  E-value: 1.47e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158  47 GGSFLGLMVFLVYLGGMLVVFGYTTAMATEEYPEAWGSNIVIlgGLFVGFLAEVVLIVWMMSDNGMGcvlcslkdmEDWV 126
Cdd:MTH00138   47 GGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPESWGSWSVL--GYVVGYLVGVVLAAGLFWGGWYE---------GSWV 115

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1003779158 127 VLGG-NEVSLVREDFVGGSALYTYGSWLVVVAGWSLFVTIFIVIEITRGR 175
Cdd:MTH00138  116 VVDElKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLELTRGL 165
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-174 1.51e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 96.07  E-value: 1.51e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158   1 MMYTVFLLSVVFVVSFIGFSSKPSPIYGGLGLIVGGGVGCGIVISLGGSFLGLMVFLVYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158  81 AWGSNIVIlggLFVGFLAEVVLIVWMMsdngmgcvLCSLKDMEDWVVLGGNEVSLVREDFVGGSALYTYGSWLVVVAGWS 160
Cdd:MTH00065   81 AWGSWSVL---VYVLFYLLLLIVGYIL--------FGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWV 149

                         170
                  ....*....|....
gi 1003779158 161 LFVTIFIVIEITRG 174
Cdd:MTH00065  150 LLLTLFVVLEVTRG 163
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-174 1.69e-21

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 85.57  E-value: 1.69e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158   1 MMYTVFLLSVVFVVSFIGFSSKPSPIYGGLGLIVGGGVGCGIVISLGGSFLGLMVFLVYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158  81 AWGSNIVilGGLFVGFLAEVVLIVWMmsdngMGCVLCSLKDMEDWVVLGGneVSLVREDFVGGSALYTYGSWLVVVAGWS 160
Cdd:MTH00115   81 AWGDWGV--VGYVVGFVLVVVVVGVV-----VGGLWGMEGVGVVTVDSGG--LFVVRLDFSGVSLFYSSGGGGLLVCGWG 151

                         170
                  ....*....|....
gi 1003779158 161 LFVTIFIVIEITRG 174
Cdd:MTH00115  152 LLLTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-175 3.08e-11

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 58.46  E-value: 3.08e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158   1 MMYTVFLLSVVFVVSFIGFSSKPSPIYGGLGLIVGGGVGCGIVISLGGSFLGLMVFLVYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158  81 AWGSNIVILGGLFVGFLAEVVlivwmmsdngmGCVLCSLKDMEDWVVLGGNEvslvREDFVGGSALYTYGSWLVVVAGWS 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFV-----------GFYFYGGWEMLSWMGVDEAN----NLDLSGVSDLYSRGFFLLLLGGVV 145

                         170
                  ....*....|....*
gi 1003779158 161 LFVTIFIVIEITRGR 175
Cdd:MTH00214  146 LFLVLFVVLELVRGL 160
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 46-174 1.63e-10

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 56.45  E-value: 1.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158  46 LGGSFLGLMVFLVYLGGMLVVFGYTTAMATEEYPeawgsNIVILGGLFVGFLaevVLIVWmmsdngmgcVLCSLKDMEDW 125
Cdd:MTH00045   44 LGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP-----SVSNLGEVLVLSL---LLSLW---------VFISFDNFLEL 106

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1003779158 126 VVLGGNEVSLvrEDFVGGSALYTYGSWLVVVAGWSLFVTIFIVIEITRG 174
Cdd:MTH00045  107 SNNNWSLVSL--SDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFG 153
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
45-171 3.86e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.51  E-value: 3.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003779158  45 SLGGSFLGLMVFLVYLGGMLVVFGYTTAMATEEYPEAWGSNIVILGGLFVGFLAEVVLIVWMMSDNGMGcvlcslkDMED 124
Cdd:pfam00499  29 LLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGLLLLALLLLVLLSASLTP-------AAAA 101

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1003779158 125 WVVLGGNEVSLvredfvgGSALYTYGSWLVVVAGWSLFVTIFIVIEI 171
Cdd:pfam00499 102 AAPDVGNIEAI-------GELLFTDYLLPFELASVLLLVALVGAIVL 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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