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Conserved domains on  [gi|1002285138|ref|XP_015646865|]
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uncharacterized protein [Oryza sativa Japonica Group]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 11454890)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

EC:  2.1.1.-
Gene Ontology:  GO:0032259|GO:0008168|GO:1904047
PubMed:  12504684|12826405

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 87-219 5.42e-15

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


:

Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 70.05  E-value: 5.42e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138  87 APYDWYQRyaALRPFVRRFAPPESRVLMIGCGSALMSEDMVDDGYtEIMNIDISSVVIEIMRkKHFNIPQLQYMQMDARD 166
Cdd:COG2227     5 DARDFWDR--RLAALLARLLPAGGRVLDVGCGTGRLALALARRGA-DVTGVDISPEALEIAR-ERAAELNVDFVQGDLED 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1002285138 167 MSiFSDESFDCAIdkgtldslMCGVGAPL-SAAQMVLEVERLLKPGGIFMLITY 219
Cdd:COG2227    81 LP-LEDGSFDLVI--------CSEVLEHLpDPAALLRELARLLKPGGLLLLSTP 125
 
Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 87-219 5.42e-15

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 70.05  E-value: 5.42e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138  87 APYDWYQRyaALRPFVRRFAPPESRVLMIGCGSALMSEDMVDDGYtEIMNIDISSVVIEIMRkKHFNIPQLQYMQMDARD 166
Cdd:COG2227     5 DARDFWDR--RLAALLARLLPAGGRVLDVGCGTGRLALALARRGA-DVTGVDISPEALEIAR-ERAAELNVDFVQGDLED 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1002285138 167 MSiFSDESFDCAIdkgtldslMCGVGAPL-SAAQMVLEVERLLKPGGIFMLITY 219
Cdd:COG2227    81 LP-LEDGSFDLVI--------CSEVLEHLpDPAALLRELARLLKPGGLLLLSTP 125
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 112-212 5.85e-13

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 63.74  E-value: 5.85e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 112 VLMIGCGSALMSEDMVDDGYTEIMNIDISSVVIEIMRKKH-FNIPQLQYMQMDARDMSiFSDESFDCAIDKGTLDSLmcg 190
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAaEAGLNVEFVQGDAEDLP-FPDGSFDLVVSSGVLHHL--- 76

                          90       100
                  ....*....|....*....|..
gi 1002285138 191 vgAPLSAAQMVLEVERLLKPGG 212
Cdd:pfam13649  77 --PDPDLEAALREIARVLKPGG 96
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 111-219 7.02e-10

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 55.51  E-value: 7.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 111 RVLMIGCGSALMSEDMVDDGYTEIMNIDISSVVIEIMRKKHFN--IPQLQYMQMDARDMSIFSDESFDCAIdkgtldSLM 188
Cdd:cd02440     1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAAllADNVEVLKGDAEELPPEADESFDVII------SDP 74

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1002285138 189 CGVGAPLSAAQMVLEVERLLKPGGIFMLITY 219
Cdd:cd02440    75 PLHHLVEDLARFLEEARRLLKPGGVLVLTLV 105
PRK08317 PRK08317
hypothetical protein; Provisional
 99-212 4.86e-05

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 43.77  E-value: 4.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138  99 RPFVRRF---------APPESRVLMIGCG----SALMSEDMVDDGytEIMNIDISSVVIEIMRK-KHFNIPQLQYMQMDA 164
Cdd:PRK08317    1 LPDFRRYrartfellaVQPGDRVLDVGCGpgndARELARRVGPEG--RVVGIDRSEAMLALAKErAAGLGPNVEFVRGDA 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1002285138 165 RDMSiFSDESFDCAIDKGTLDSLmcgvgapLSAAQMVLEVERLLKPGG 212
Cdd:PRK08317   79 DGLP-FPDGSFDAVRSDRVLQHL-------EDPARALAEIARVLRPGG 118
 
Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 87-219 5.42e-15

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 70.05  E-value: 5.42e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138  87 APYDWYQRyaALRPFVRRFAPPESRVLMIGCGSALMSEDMVDDGYtEIMNIDISSVVIEIMRkKHFNIPQLQYMQMDARD 166
Cdd:COG2227     5 DARDFWDR--RLAALLARLLPAGGRVLDVGCGTGRLALALARRGA-DVTGVDISPEALEIAR-ERAAELNVDFVQGDLED 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1002285138 167 MSiFSDESFDCAIdkgtldslMCGVGAPL-SAAQMVLEVERLLKPGGIFMLITY 219
Cdd:COG2227    81 LP-LEDGSFDLVI--------CSEVLEHLpDPAALLRELARLLKPGGLLLLSTP 125
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 89-225 3.88e-14

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 68.48  E-value: 3.88e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138  89 YDWY-QRYAALRPFVRRFAP-PESRVLMIGCGSALMSEDMVDDGYtEIMNIDISSVVIEIMRKKHFNIP-QLQYMQMDAR 165
Cdd:COG2226     1 FDRVaARYDGREALLAALGLrPGARVLDLGCGTGRLALALAERGA-RVTGVDISPEMLELARERAAEAGlNVEFVVGDAE 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 166 DMSiFSDESFDCAIDKGTLdslmCGVGAPLSAAQmvlEVERLLKPGGIFMLITYGDPSVR 225
Cdd:COG2226    80 DLP-FPDGSFDLVISSFVL----HHLPDPERALA---EIARVLKPGGRLVVVDFSPPDLA 131
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 112-212 5.85e-13

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 63.74  E-value: 5.85e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 112 VLMIGCGSALMSEDMVDDGYTEIMNIDISSVVIEIMRKKH-FNIPQLQYMQMDARDMSiFSDESFDCAIDKGTLDSLmcg 190
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAaEAGLNVEFVQGDAEDLP-FPDGSFDLVVSSGVLHHL--- 76

                          90       100
                  ....*....|....*....|..
gi 1002285138 191 vgAPLSAAQMVLEVERLLKPGG 212
Cdd:pfam13649  77 --PDPDLEAALREIARVLKPGG 96
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
74-246 1.18e-12

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 65.02  E-value: 1.18e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138  74 AEYWDARYVEEggAPYDWYQRYAALrpFVRRFAP-PESRVLMIGCGSALMSEDMVDDGYtEIMNIDISSVVIEIMRKKHF 152
Cdd:COG4976    15 ADSYDAALVED--LGYEAPALLAEE--LLARLPPgPFGRVLDLGCGTGLLGEALRPRGY-RLTGVDLSEEMLAKAREKGV 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 153 NIpqlQYMQMDARDMSiFSDESFDCAIdkgtldslMCGVGAPLSAAQMVL-EVERLLKPGGIFML-ITYGDPSVRVPH-- 228
Cdd:COG4976    90 YD---RLLVADLADLA-EPDGRFDLIV--------AADVLTYLGDLAAVFaGVARALKPGGLFIFsVEDADGSGRYAHsl 157

                         170       180
                  ....*....|....*....|....
gi 1002285138 229 ------LNQSGCNWKIVLYILPRP 246
Cdd:COG4976   158 dyvrdlLAAAGFEVPGLLVVARKP 181
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 113-216 1.56e-12

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 62.68  E-value: 1.56e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 113 LMIGCGSALMSEDMVDDGYtEIMNIDISSVVIEIMRKKhFNIPQLQYMQMDARDMSiFSDESFDCAIDKGTLDSLMcgvg 192
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGA-RVTGVDISPEMLELAREK-APREGLTFVVGDAEDLP-FPDNSFDLVLSSEVLHHVE---- 73

                          90       100
                  ....*....|....*....|....
gi 1002285138 193 aplSAAQMVLEVERLLKPGGIFML 216
Cdd:pfam08241  74 ---DPERALREIARVLKPGGILII 94
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 76-217 1.36e-11

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 62.63  E-value: 1.36e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138  76 YWDARYVEEGgAPYdwyqrYAALRPFVRRFaPPESRVLMIGCGSALMSEDMVDDGYTEIMNIDISSVVIEIMRKK--HFN 153
Cdd:COG0500     1 PWDSYYSDEL-LPG-----LAALLALLERL-PKGGRVLDLGCGTGRNLLALAARFGGRVIGIDLSPEAIALARARaaKAG 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002285138 154 IPQLQYMQMDARDMSIFSDESFDCAIDKGTLDSLmcgvgAPLSAAQMVLEVERLLKPGGIFMLI 217
Cdd:COG0500    74 LGNVEFLVADLAELDPLPAESFDLVVAFGVLHHL-----PPEEREALLRELARALKPGGVLLLS 132
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 111-219 7.02e-10

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 55.51  E-value: 7.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 111 RVLMIGCGSALMSEDMVDDGYTEIMNIDISSVVIEIMRKKHFN--IPQLQYMQMDARDMSIFSDESFDCAIdkgtldSLM 188
Cdd:cd02440     1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAAllADNVEVLKGDAEELPPEADESFDVII------SDP 74

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1002285138 189 CGVGAPLSAAQMVLEVERLLKPGGIFMLITY 219
Cdd:cd02440    75 PLHHLVEDLARFLEEARRLLKPGGVLVLTLV 105
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 111-235 2.96e-09

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 54.73  E-value: 2.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 111 RVLMIGCGSA----LMSEDMVDDGytEIMNIDISSVVIEIMRKkhfNIPQLQY--MQMDARDM----SIFSDESFDCAID 180
Cdd:pfam13847   6 RVLDLGCGTGhlsfELAEELGPNA--EVVGIDISEEAIEKARE---NAQKLGFdnVEFEQGDIeelpELLEDDKFDVVIS 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1002285138 181 KGTLdslmCGVGAPLSAAQmvlEVERLLKPGGIFMlITYGDPSVRVPHLNQSGCN 235
Cdd:pfam13847  81 NCVL----NHIPDPDKVLQ---EILRVLKPGGRLI-ISDPDSLAELPAHVKEDST 127
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 91-245 3.37e-08

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 52.05  E-value: 3.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138  91 WYQRYAALRPFVRRFAPPES---RVLMIGCGSALMSEDMVDDGYTeIMNIDISSVVIEIMRKkhfNIPQLQYMQMDARdm 167
Cdd:pfam13489   2 AHQRERLLADLLLRLLPKLPspgRVLDFGCGTGIFLRLLRAQGFS-VTGVDPSPIAIERALL---NVRFDQFDEQEAA-- 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002285138 168 siFSDESFDCAIDKGTLDSlmcgVGAPLSAAQMVLeveRLLKPGGIFMLITYgDPSVRVPHLNQsgcNWkivLYILPR 245
Cdd:pfam13489  76 --VPAGKFDVIVAREVLEH----VPDPPALLRQIA---ALLKPGGLLLLSTP-LASDEADRLLL---EW---PYLRPR 137
PRK08317 PRK08317
hypothetical protein; Provisional
 99-212 4.86e-05

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 43.77  E-value: 4.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138  99 RPFVRRF---------APPESRVLMIGCG----SALMSEDMVDDGytEIMNIDISSVVIEIMRK-KHFNIPQLQYMQMDA 164
Cdd:PRK08317    1 LPDFRRYrartfellaVQPGDRVLDVGCGpgndARELARRVGPEG--RVVGIDRSEAMLALAKErAAGLGPNVEFVRGDA 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1002285138 165 RDMSiFSDESFDCAIDKGTLDSLmcgvgapLSAAQMVLEVERLLKPGG 212
Cdd:PRK08317   79 DGLP-FPDGSFDAVRSDRVLQHL-------EDPARALAEIARVLRPGG 118
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
108-216 7.56e-05

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 40.96  E-value: 7.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 108 PESRVLMIGCGSALMSEDMVD-DGYTEIMNIDISSVVIEIMRKKHfniPQLQYMQMDARDMSIfsDESFDCAIDKGTL-- 184
Cdd:COG4106     1 PPRRVLDLGCGTGRLTALLAErFPGARVTGVDLSPEMLARARARL---PNVRFVVADLRDLDP--PEPFDLVVSNAALhw 75

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1002285138 185 -DSLmcgvgaplsaAQMVLEVERLLKPGGIFML 216
Cdd:COG4106    76 lPDH----------AALLARLAAALAPGGVLAV 98
TPMT pfam05724
Thiopurine S-methyltransferase (TPMT); This family consists of thiopurine S-methyltransferase ...
 73-222 8.43e-04

Thiopurine S-methyltransferase (TPMT); This family consists of thiopurine S-methyltransferase proteins from both eukaryotes and prokaryotes. Thiopurine S-methyltransferase (TPMT) is a cytosolic enzyme that catalyzes S-methylation of aromatic and heterocyclic sulfhydryl compounds, including anticancer and immunosuppressive thiopurines.


Pssm-ID: 399030  Cd Length: 218  Bit Score: 40.10  E-value: 8.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138  73 KAEYWDARYVEeGGAPYDWYQRYAALRPFVRRF-APPESRVLMIGCGSALmseDMV---DDGYtEIMNIDISSVVIEIMR 148
Cdd:pfam05724   2 DPDFWLKRWVE-GQTPFHQEGVNPLLVRHWDALkLPPGLRVLVPLCGKAL---DMVwlaEQGH-FVVGVEISELAVEKFF 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 149 KKHFNIPQLQYMQ----MDARDMSIFSDESFDC-AIDKGTLDSL-----MCGVGAPLSAAqMVLEVERLLKPGGIFMLIT 218
Cdd:pfam05724  77 AEAGLSPPITELSgfkeYSSGNISLYCGDFFTLpREELGKFDLIydraaLCALPPEMRPR-YAKQMYELLPPGGRGLLIT 155


                  ....
gi 1002285138 219 YGDP 222
Cdd:pfam05724 156 LDYP 159
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 96-218 1.11e-03

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 38.76  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138  96 AALRPFVRRFA-----PPESRVLMIGCGSALMSEDMVDDGYTEIMNIDISSVVIEIMRKKHFNI---PQLQYMQMDARDm 167
Cdd:COG2230    34 EAQEAKLDLILrklglKPGMRVLDIGCGWGGLALYLARRYGVRVTGVTLSPEQLEYARERAAEAglaDRVEVRLADYRD- 112

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1002285138 168 sIFSDESFDCAIDKGTLdslmCGVGaPLSAAQMVLEVERLLKPGGIFMLIT 218
Cdd:COG2230   113 -LPADGQFDAIVSIGMF----EHVG-PENYPAYFAKVARLLKPGGRLLLHT 157
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 115-214 3.99e-03

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 36.19  E-value: 3.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 115 IGCGSALMSEDMVDD-GYTEIMNIDISSVVIEIMRKKHFNIPQLQYMQMDARDMSIFSDE--SFDCAIdkgtldslMCGV 191
Cdd:pfam08242   3 IGCGTGTLLRALLEAlPGLEYTGLDISPAALEAARERLAALGLLNAVRVELFQLDLGELDpgSFDVVV--------ASNV 74

                          90       100
                  ....*....|....*....|....*..
gi 1002285138 192 gapLSA----AQMVLEVERLLKPGGIF 214
Cdd:pfam08242  75 ---LHHladpRAVLRNIRRLLKPGGVL 98
rrmA PRK11088
23S rRNA methyltransferase A; Provisional
 104-218 5.97e-03

23S rRNA methyltransferase A; Provisional


Pssm-ID: 236841 [Multi-domain]  Cd Length: 272  Bit Score: 37.58  E-value: 5.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285138 104 RFAPPESRVLMIGCG----SALMSEDMVDDGYTEIMNIDISSVVIEIMRKKHfniPQLQYMQMDARDMSiFSDESFDcai 179
Cdd:PRK11088   81 RLDEKATALLDIGCGegyyTHALADALPEITTMQLFGLDISKVAIKYAAKRY---PQVTFCVASSHRLP-FADQSLD--- 153

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1002285138 180 dkgtldsLMCGVGAPLSAAqmvlEVERLLKPGGIfmLIT 218
Cdd:PRK11088  154 -------AIIRIYAPCKAE----ELARVVKPGGI--VIT 179
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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