|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
94-989 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 1345.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 94 ASSGEWSGDAIRRRFLDFYAARGHKILPSSSLVP-DDPTVFLTIAGMLQFKPIFLGK-----EPRRVPCATTSQKCIRT- 166
Cdd:PLN02900 6 APEKEWPGDRIRRTFLSFFESKGHTFLPSSPLVPvDDPTLLFTNAGMNQFKPIFLGTadpntPLRKLPRATNTQKCIRAg 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 167 ---NDIENVGRTSRHQTFFEMLGNFSFGDYFKKEAITWAWELTTKEFGLPPERLWISVFQDDD------EAFSIWHNEVg 237
Cdd:PLN02900 86 gkhNDLDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEkqapddEARAIWLDYL- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 238 vPKERIKRLGEDDNFWTSGATGPCGPCSEIYYDFYPERGSSDADLGDDSRFIEFYNLVFMQYNKKDDGSLEPLKQKNIDT 317
Cdd:PLN02900 165 -PEERVLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLPAKHVDT 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 318 GMGLERMARILQKVPNNYETDLIFPIIEKAAS------MALVSYTTADDAMKTNLKIIGDHMRAVVYLISDGVIPSNIGR 391
Cdd:PLN02900 244 GMGLERLASILQNKPSNYDTDLFMPIFDAIQEatgarpYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGR 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 392 GYVVRRLIRRVVRTGRLIgirgdghGNSEGAFLPSLAEVAISLSTEIDPDVESRRKSILGELQREELRFVQTLERGEKll 471
Cdd:PLN02900 324 GYVLRRLLRRAVRYGRLL-------LGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIE-- 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 472 deLLDEALSSAGNNGGkPCLSGKDVFLLYDTYGFPVEITAEISGERGVIVDMKGFDMEMENQRKQSQAAHN-----VVKL 546
Cdd:PLN02900 395 --KFKKALAAAKANGG-PVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAHLkagggAIEL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 547 SVGNETEIVK--SIPDTEFLGYDSLS-ATAVVKGLLVNGNSVNVVSEGSDVEIFLDRTPFYAESGGQVGDNGFLYVYGEe 623
Cdd:PLN02900 472 AAEATSWLQKqgVAATDDFLKYDWLSdHEAVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGG- 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 624 dakqkAVIEINDVQKSlGNIFVHKGTIKQGSVEVGKEIDAAVDAKLRQGAKAHHTATHLLQSALKSIIGSETSQAGSLVA 703
Cdd:PLN02900 551 -----AVVEVSDVQKA-GGFVLHIGTVTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVA 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 704 FDRLRFDFNFHRPLSEEELMKIESLVNQWVSSATHLETKVMDLQDAKN-AGAIAMFGEKYGEQVRVVEVPGV-SMELCGG 781
Cdd:PLN02900 625 FEKLRFDFSHGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRiNGLRAVFGEKYPDPVRVVSVGGVySMELCGG 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 782 THVSNTAEIRGFKIISEQGIASGVRRIEAVAGDAFVEYVCARDNYMRCLCSSLKV------------------------K 837
Cdd:PLN02900 705 THVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSALKVegsdlekkvaslksrvdaavipaaK 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 838 AEDVNGRVETILEELRTTRNEVSSLRSKIAVLKAASLANKATTiDNTRVVVENMGD-VDADGLKSAAEYLVDTLEDPAAV 916
Cdd:PLN02900 785 KEEIRARVSALQKELRAAQKEAAALRAKLAVAKATELASKALS-AGKSVLVARLDVgVDAAALKEAAEKVIAKLGDPAAV 863
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002279858 917 ILGSSPGDGKVSLVAAFSPGVVKMGIQAGKFVGGIAKLCGGGGGGKPNFAQAGGRKPENLPGALEKARDEIVA 989
Cdd:PLN02900 864 VLSSDEEKGKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKARAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
100-991 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1209.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 100 SGDAIRRRFLDFYAARGHKILPSSSLVP-DDPTVFLTIAGMLQFKPIFLGKEPRRVPCATTSQKCIRT----NDIENVGR 174
Cdd:COG0013 3 TSAEIRQKFLDFFESKGHTIVPSSSLVPkNDPTLLFTNAGMVQFKPYFLGQEKPPYPRATTSQKCVRTggkhNDLENVGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 175 TSRHQTFFEMLGNFSFGDYFKKEAITWAWELTTKEFGLPPERLWISVFQDDDEAFSIWHNEVGVPKERIKRLGEDDNFWT 254
Cdd:COG0013 83 TARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDDEAYDIWKKEIGVPEERIIRLGKKDNFWE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 255 SGATGPCGPCSEIYYDFYPE--RGSSDADLGDDSRFIEFYNLVFMQYNKKDDGSLEPLKQKNIDTGMGLERMARILQKVP 332
Cdd:COG0013 163 MGDTGPCGPCSEIFYDRGPEygGGPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLERIAAVLQGVH 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 333 NNYETDLIFPIIEKAASMALVSYTtADDAMKTNLKIIGDHMRAVVYLISDGVIPSNIGRGYvvrrlirrvvrtGRLIGIr 412
Cdd:COG0013 243 SNYETDLFRPLIEAAAELTGVKYG-ADEEDDVSLRVIADHIRAVAFLIADGVLPSNEGRGYvlrrilrravrhGRLLGI- 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 413 gdghgnsEGAFLPSLAEVAISLSTEIDPDVESRRKSILGELQREELRFVQTLERGEKLLDELLdealSSAGNNGGKpCLS 492
Cdd:COG0013 321 -------KEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAI----AKLKAAGGK-VLS 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 493 GKDVFLLYDTYGFPVEITAEISGERGVIVDMKGFDMEMENQRKQSQAAHNVVKLSVGNE--TEIVKSIPDTEFLGYDSLS 570
Cdd:COG0013 389 GEDAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDAAVDGvwRELLEEGGPTEFVGYDTLE 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 571 ATAVVKGLLVNGNSVNVVSEGSDVEIFLDRTPFYAESGGQVGDNGFLYVYGeedakqkAVIEINDVQKSLGNIFVHKGTI 650
Cdd:COG0013 469 AEAKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEGDG-------GVFEVTDTQKPPGGLIVHIGKV 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 651 KQGSVEVGKEIDAAVDAKLRQGAKAHHTATHLLQSALKSIIGSETSQAGSLVAFDRLRFDFNFHRPLSEEELMKIESLVN 730
Cdd:COG0013 542 EEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVN 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 731 QWVSSATHLETKVMDLQDAKNAGAIAMFGEKYGEQVRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGVRRIEA 810
Cdd:COG0013 622 EKIRENLPVETREMPLDEAKALGAMALFGEKYGDEVRVVSIGDFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEA 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 811 VAGDAFVEYVCARDNYMRCLCSSLKVKAEDVNGRVETILEELRTTRNEVSSLRSKIAVLKAASLANKATTIDNTRVVVEN 890
Cdd:COG0013 702 VTGEAALEYLREQEALLKELAELLKAPPEELPERVEALLEELKELEKELEQLKAKLASAAADDLLAQAEEIGGVKVLAAR 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 891 MGDVDADGLKSAAEYLVDTLEDpAAVILGSSpGDGKVSLVAAFSPGVVKMGIQAGKFVGGIAKLCGGGGGGKPNFAQAGG 970
Cdd:COG0013 782 VEGVDAKDLRDLADDLKDKLGS-GVVVLASV-ADGKVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRPDMAQAGG 859
|
890 900
....*....|....*....|.
gi 1002279858 971 RKPENLPGALEKARDEIVAAI 991
Cdd:COG0013 860 KDPSKLDEALAAVKEWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
104-970 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 932.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 104 IRRRFLDFYAARGHKILPSSSLVP-DDPTVFLTIAGMLQFKPIFLGKEPRRVPCATTSQKCIRTNDIENVGRTSRHQTFF 182
Cdd:TIGR00344 2 IRQTFLDFFKEKGHQVIPSAPLVPrNDPTLLLTNAGMAQFKPIFTGIVKPPSNRLTNAQPCIRLNDLENVGRTARHHTLF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 183 EMLGNFSFGDYFKKEAITWAWELTTKEFGLPPERLWISVFQDDDEAFSIWhNEVGVPKERIKRLGEDDNFWTSGaTGPCG 262
Cdd:TIGR00344 82 EMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDEEAYKIW-EKIGIPADRIIKCDAKDNFWDMG-DGPCG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 263 PCSEIYYDFYPerGSSDADLGDDSRFIEFYNLVFMQYNKKDDGSLEPLKQKNIDTGMGLERMARILQKVPNNYETDLIFP 342
Cdd:TIGR00344 160 PCTEIYYDFVG--GKPGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVAVLQGVPTNYDTDIFLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 343 IIEKAASMALVSYTTADDAM--------KTNLKIIGDHMRAVVYLISDGVIPSNIGRGYVVrrlirrvvrtgRLIGIRGD 414
Cdd:TIGR00344 238 LIEKIEEITGVKYDSNNAGImdekrvedLRSLRVIADHTRAIAFMLADGVVPSNEGRGYVL-----------RRLIRRAL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 415 GHG---NSEGAFLPSLAEVAISLSTEIDPDVESRRKSILGELQREELRFVQTLERGEKLLDELLDEALSSAgnnggkpcL 491
Cdd:TIGR00344 307 RHGkklGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGKKE--------L 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 492 SGKDVFLLYDTYGFPVEITAEISGERGVIVDMKGFDMEMENQRKQSQAAHNVVKlsvgNETEIVKSIPDTEFLGYDSLSA 571
Cdd:TIGR00344 379 DGEDAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQE----QEIALVNVYPATEFLGYDDLEF 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 572 TAVVKGLLVNGNSVNVVSEGSDVEIFLDRTPFYAESGGQVGDNGFLYvygeedaKQKAVIEINDVQKSlGNIFVHKGTIK 651
Cdd:TIGR00344 455 EAKVIGLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLI-------ANDGKFRVVDVQKP-NGVVFHFGEVE 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 652 QGSVEVGKEIDAAVDAKLRQGAKAHHTATHLLQSALKSIIGSETSQAGSLVAFDRLRFDFNFHRPLSEEELMKIESLVNQ 731
Cdd:TIGR00344 527 GGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLANE 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 732 WVSSATHLETKVMDLQDAKNAGAIAMFGEKY--GEQVRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGVRRIE 809
Cdd:TIGR00344 607 QILANIPIKVIFMDLDEAKRKGAFALFGEKYvpGEKVRVVSVGDFSVELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIE 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 810 AVAGDAFVEYVCARDNYMRCLCSSLKVKAEDVNGRVETILEELRTTRNEVSSLRSKIAVLKAASLANKATTIDNTRVVVE 889
Cdd:TIGR00344 687 AVTGEAAIEYLNEQEDKLKELADILKVTPNELPKKVERFFEEWKALQKELESLKLKIADQKIDELKDKAETINGVKVLVE 766
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 890 NMGDVDADGLKSAAEYLVDTLEDpaAVILGSSPGDGKVSLVAAFSPGVVKMGIQAGKFVGGIAKLCGGGGGGKPNFAQAG 969
Cdd:TIGR00344 767 VVDAKDMKSLKTMADRLKSKLGS--AIYVLASFAEGKVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQGG 844
|
.
gi 1002279858 970 G 970
Cdd:TIGR00344 845 G 845
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
104-668 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 660.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 104 IRRRFLDFYAARGHKILPSSSLVP-DDPTVFLTIAGMLQFKPIFLGKEPRR-VPCATTSQKCIRTNDIENVGRTSRHQTF 181
Cdd:pfam01411 2 IRQTFLDFFEKKGHTRVPSSPVVPrNDPTLLFTNAGMNQFKPIFLGGVAKPpYNRATNSQKCIRAGDLENVGRTGRHHTF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 182 FEMLGNFSFGDYFKKEAITWAWELTTKEFGLPPERLWISVFQDDDEAFSIWHNEVGVPKERIKRLGEDDNFWTSGATGPC 261
Cdd:pfam01411 82 FEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDDEAGPIWEKIVGGPEERILRFGDKDNFWEMGDTGPC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 262 GPCSEIYYDFYPERGSSDA---DLGDDSRFIEFYNLVFMQYNKKDDGSLEPLKQKNIDTGMGLERMARILQKVPNNYETD 338
Cdd:pfam01411 162 GPCSEIDYDRGEEIGGWDSggtPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLERLVAVLQDVRSNYDTD 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 339 LIFPIIEKAASMALVSYTTaDDAMKTNLKIIGDHMRAVVYLISDGVIPSNIGRGYVVrrlirrvvrtgRLIGIRGDGHG- 417
Cdd:pfam01411 242 VFIPVIELIEEISGARYYT-VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVL-----------RRILRRAVRHAk 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 418 --NSEGAFLPSLAEVAISLSTEIDPDVESRRKSILGELQREELRFVQTLERGEKLLDELLdealssAGNNGGKPCLSGKD 495
Cdd:pfam01411 310 klGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLI------AKLKKGKKTLPGED 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 496 VFLLYDTYGFPVEITAEISGERGVIVDMKGFDMEMENQRKQSQAAHNVVKLSVGNEtEIVKSIPDTEFLGYDSLSATAVV 575
Cdd:pfam01411 384 AFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKGEKLDVS-ALKELPATTEFLGYDDLESEAKI 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 576 KGLLVNGNSVNVVSEGSDVEIFLDRTPFYAESGGQVGDNGFLYVYGEEdakqkavIEINDVQKSlGNIFVHKGTIKQGSV 655
Cdd:pfam01411 463 LALPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIGDGGE-------FRVTDVQKY-GGVVVHKGKLESGKL 534
|
570
....*....|...
gi 1002279858 656 EVGKEIDAAVDAK 668
Cdd:pfam01411 535 KVGDKVIAVIDED 547
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
102-331 |
3.60e-134 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 402.89 E-value: 3.60e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 102 DAIRRRFLDFYAARGHKILPSSSLVP-DDPTVFLTIAGMLQFKPIFLGKEPRRVPCATTSQKCIRTNDIENVGRTSRHQT 180
Cdd:cd00673 2 SEIRETFLSFFEKKGHTRVPSSPVVPrDDPTLLFTNAGMNQFKPIFLGEVPPPANRLVNSQKCIRAGDIDNVGKTGRHHT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 181 FFEMLGNFSFGDYFKKEAITWAWELTTKEFGLPPERLWISVFQDDDEAFSIWHNEVGVPKERIKRLGEDDNFWTSGATGP 260
Cdd:cd00673 82 FFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGDDEEEAIWWWKIGLPGIRIERIGFKDNFWEMGGNGP 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002279858 261 CGPCSEIYYDFYPERGSSDADLGDDSRFIEFYNLVFMQYNKKDDGSLEPLKQKNIDTGMGLERMARILQKV 331
Cdd:cd00673 162 CGPCSEIFYDRGEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERLVWVLQGV 232
|
|
| a_tRNA_ed_AlaXM |
NF040865 |
alanyl-tRNA editing protein AlaXM; |
585-809 |
5.42e-26 |
|
alanyl-tRNA editing protein AlaXM;
Pssm-ID: 468802 [Multi-domain] Cd Length: 234 Bit Score: 107.31 E-value: 5.42e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 585 VNVVSEGsdveIFLDRTPFYAESGGQVGDNGFLYVYGEEdakqkavIEINDVQKSLGNIfVHKGTiKQGSVEVGKEIDAA 664
Cdd:NF040865 19 VRVKGNG----VVLDRTAFYPTGGGQPHDTGTLVRDDKE-------FRVVDVRKEGGEI-AHVVD-RAPGLKPGDKVKGE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 665 VDAKLRQGAKAHHTATHLLQSALKSIIGSETSqaGSLVAFDRLRFDFNFHRpLSEEELMKIESLVNQWVSSATHLETKVM 744
Cdd:NF040865 86 IDWDRRYRLMRYHTASHILSAVLYREYGALIT--GGQISPDKARVDFSLEN-FDRELLEEIIEEANEIIAEGIEVKIYWL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002279858 745 DLQDAKNAGAIAMFGEKYGEQ---VRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGVRRIE 809
Cdd:NF040865 163 PREEALKIPGLVRLAKRLPPEieeVRIVEIEGVDIQADGGTHVKNTGEIGEIKILKRENKGKGNKRLY 230
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
766-808 |
4.51e-18 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 78.19 E-value: 4.51e-18
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1002279858 766 VRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGVRRI 808
Cdd:smart00863 1 VRVVSIGDFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
94-989 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 1345.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 94 ASSGEWSGDAIRRRFLDFYAARGHKILPSSSLVP-DDPTVFLTIAGMLQFKPIFLGK-----EPRRVPCATTSQKCIRT- 166
Cdd:PLN02900 6 APEKEWPGDRIRRTFLSFFESKGHTFLPSSPLVPvDDPTLLFTNAGMNQFKPIFLGTadpntPLRKLPRATNTQKCIRAg 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 167 ---NDIENVGRTSRHQTFFEMLGNFSFGDYFKKEAITWAWELTTKEFGLPPERLWISVFQDDD------EAFSIWHNEVg 237
Cdd:PLN02900 86 gkhNDLDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEkqapddEARAIWLDYL- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 238 vPKERIKRLGEDDNFWTSGATGPCGPCSEIYYDFYPERGSSDADLGDDSRFIEFYNLVFMQYNKKDDGSLEPLKQKNIDT 317
Cdd:PLN02900 165 -PEERVLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLPAKHVDT 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 318 GMGLERMARILQKVPNNYETDLIFPIIEKAAS------MALVSYTTADDAMKTNLKIIGDHMRAVVYLISDGVIPSNIGR 391
Cdd:PLN02900 244 GMGLERLASILQNKPSNYDTDLFMPIFDAIQEatgarpYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGR 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 392 GYVVRRLIRRVVRTGRLIgirgdghGNSEGAFLPSLAEVAISLSTEIDPDVESRRKSILGELQREELRFVQTLERGEKll 471
Cdd:PLN02900 324 GYVLRRLLRRAVRYGRLL-------LGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIE-- 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 472 deLLDEALSSAGNNGGkPCLSGKDVFLLYDTYGFPVEITAEISGERGVIVDMKGFDMEMENQRKQSQAAHN-----VVKL 546
Cdd:PLN02900 395 --KFKKALAAAKANGG-PVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAHLkagggAIEL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 547 SVGNETEIVK--SIPDTEFLGYDSLS-ATAVVKGLLVNGNSVNVVSEGSDVEIFLDRTPFYAESGGQVGDNGFLYVYGEe 623
Cdd:PLN02900 472 AAEATSWLQKqgVAATDDFLKYDWLSdHEAVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGG- 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 624 dakqkAVIEINDVQKSlGNIFVHKGTIKQGSVEVGKEIDAAVDAKLRQGAKAHHTATHLLQSALKSIIGSETSQAGSLVA 703
Cdd:PLN02900 551 -----AVVEVSDVQKA-GGFVLHIGTVTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVA 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 704 FDRLRFDFNFHRPLSEEELMKIESLVNQWVSSATHLETKVMDLQDAKN-AGAIAMFGEKYGEQVRVVEVPGV-SMELCGG 781
Cdd:PLN02900 625 FEKLRFDFSHGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRiNGLRAVFGEKYPDPVRVVSVGGVySMELCGG 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 782 THVSNTAEIRGFKIISEQGIASGVRRIEAVAGDAFVEYVCARDNYMRCLCSSLKV------------------------K 837
Cdd:PLN02900 705 THVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSALKVegsdlekkvaslksrvdaavipaaK 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 838 AEDVNGRVETILEELRTTRNEVSSLRSKIAVLKAASLANKATTiDNTRVVVENMGD-VDADGLKSAAEYLVDTLEDPAAV 916
Cdd:PLN02900 785 KEEIRARVSALQKELRAAQKEAAALRAKLAVAKATELASKALS-AGKSVLVARLDVgVDAAALKEAAEKVIAKLGDPAAV 863
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002279858 917 ILGSSPGDGKVSLVAAFSPGVVKMGIQAGKFVGGIAKLCGGGGGGKPNFAQAGGRKPENLPGALEKARDEIVA 989
Cdd:PLN02900 864 VLSSDEEKGKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKARAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
100-991 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1209.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 100 SGDAIRRRFLDFYAARGHKILPSSSLVP-DDPTVFLTIAGMLQFKPIFLGKEPRRVPCATTSQKCIRT----NDIENVGR 174
Cdd:COG0013 3 TSAEIRQKFLDFFESKGHTIVPSSSLVPkNDPTLLFTNAGMVQFKPYFLGQEKPPYPRATTSQKCVRTggkhNDLENVGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 175 TSRHQTFFEMLGNFSFGDYFKKEAITWAWELTTKEFGLPPERLWISVFQDDDEAFSIWHNEVGVPKERIKRLGEDDNFWT 254
Cdd:COG0013 83 TARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDDEAYDIWKKEIGVPEERIIRLGKKDNFWE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 255 SGATGPCGPCSEIYYDFYPE--RGSSDADLGDDSRFIEFYNLVFMQYNKKDDGSLEPLKQKNIDTGMGLERMARILQKVP 332
Cdd:COG0013 163 MGDTGPCGPCSEIFYDRGPEygGGPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLERIAAVLQGVH 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 333 NNYETDLIFPIIEKAASMALVSYTtADDAMKTNLKIIGDHMRAVVYLISDGVIPSNIGRGYvvrrlirrvvrtGRLIGIr 412
Cdd:COG0013 243 SNYETDLFRPLIEAAAELTGVKYG-ADEEDDVSLRVIADHIRAVAFLIADGVLPSNEGRGYvlrrilrravrhGRLLGI- 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 413 gdghgnsEGAFLPSLAEVAISLSTEIDPDVESRRKSILGELQREELRFVQTLERGEKLLDELLdealSSAGNNGGKpCLS 492
Cdd:COG0013 321 -------KEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAI----AKLKAAGGK-VLS 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 493 GKDVFLLYDTYGFPVEITAEISGERGVIVDMKGFDMEMENQRKQSQAAHNVVKLSVGNE--TEIVKSIPDTEFLGYDSLS 570
Cdd:COG0013 389 GEDAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDAAVDGvwRELLEEGGPTEFVGYDTLE 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 571 ATAVVKGLLVNGNSVNVVSEGSDVEIFLDRTPFYAESGGQVGDNGFLYVYGeedakqkAVIEINDVQKSLGNIFVHKGTI 650
Cdd:COG0013 469 AEAKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEGDG-------GVFEVTDTQKPPGGLIVHIGKV 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 651 KQGSVEVGKEIDAAVDAKLRQGAKAHHTATHLLQSALKSIIGSETSQAGSLVAFDRLRFDFNFHRPLSEEELMKIESLVN 730
Cdd:COG0013 542 EEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVN 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 731 QWVSSATHLETKVMDLQDAKNAGAIAMFGEKYGEQVRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGVRRIEA 810
Cdd:COG0013 622 EKIRENLPVETREMPLDEAKALGAMALFGEKYGDEVRVVSIGDFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEA 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 811 VAGDAFVEYVCARDNYMRCLCSSLKVKAEDVNGRVETILEELRTTRNEVSSLRSKIAVLKAASLANKATTIDNTRVVVEN 890
Cdd:COG0013 702 VTGEAALEYLREQEALLKELAELLKAPPEELPERVEALLEELKELEKELEQLKAKLASAAADDLLAQAEEIGGVKVLAAR 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 891 MGDVDADGLKSAAEYLVDTLEDpAAVILGSSpGDGKVSLVAAFSPGVVKMGIQAGKFVGGIAKLCGGGGGGKPNFAQAGG 970
Cdd:COG0013 782 VEGVDAKDLRDLADDLKDKLGS-GVVVLASV-ADGKVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRPDMAQAGG 859
|
890 900
....*....|....*....|.
gi 1002279858 971 RKPENLPGALEKARDEIVAAI 991
Cdd:COG0013 860 KDPSKLDEALAAVKEWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
104-970 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 932.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 104 IRRRFLDFYAARGHKILPSSSLVP-DDPTVFLTIAGMLQFKPIFLGKEPRRVPCATTSQKCIRTNDIENVGRTSRHQTFF 182
Cdd:TIGR00344 2 IRQTFLDFFKEKGHQVIPSAPLVPrNDPTLLLTNAGMAQFKPIFTGIVKPPSNRLTNAQPCIRLNDLENVGRTARHHTLF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 183 EMLGNFSFGDYFKKEAITWAWELTTKEFGLPPERLWISVFQDDDEAFSIWhNEVGVPKERIKRLGEDDNFWTSGaTGPCG 262
Cdd:TIGR00344 82 EMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDEEAYKIW-EKIGIPADRIIKCDAKDNFWDMG-DGPCG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 263 PCSEIYYDFYPerGSSDADLGDDSRFIEFYNLVFMQYNKKDDGSLEPLKQKNIDTGMGLERMARILQKVPNNYETDLIFP 342
Cdd:TIGR00344 160 PCTEIYYDFVG--GKPGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVAVLQGVPTNYDTDIFLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 343 IIEKAASMALVSYTTADDAM--------KTNLKIIGDHMRAVVYLISDGVIPSNIGRGYVVrrlirrvvrtgRLIGIRGD 414
Cdd:TIGR00344 238 LIEKIEEITGVKYDSNNAGImdekrvedLRSLRVIADHTRAIAFMLADGVVPSNEGRGYVL-----------RRLIRRAL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 415 GHG---NSEGAFLPSLAEVAISLSTEIDPDVESRRKSILGELQREELRFVQTLERGEKLLDELLDEALSSAgnnggkpcL 491
Cdd:TIGR00344 307 RHGkklGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGKKE--------L 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 492 SGKDVFLLYDTYGFPVEITAEISGERGVIVDMKGFDMEMENQRKQSQAAHNVVKlsvgNETEIVKSIPDTEFLGYDSLSA 571
Cdd:TIGR00344 379 DGEDAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQE----QEIALVNVYPATEFLGYDDLEF 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 572 TAVVKGLLVNGNSVNVVSEGSDVEIFLDRTPFYAESGGQVGDNGFLYvygeedaKQKAVIEINDVQKSlGNIFVHKGTIK 651
Cdd:TIGR00344 455 EAKVIGLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLI-------ANDGKFRVVDVQKP-NGVVFHFGEVE 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 652 QGSVEVGKEIDAAVDAKLRQGAKAHHTATHLLQSALKSIIGSETSQAGSLVAFDRLRFDFNFHRPLSEEELMKIESLVNQ 731
Cdd:TIGR00344 527 GGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLANE 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 732 WVSSATHLETKVMDLQDAKNAGAIAMFGEKY--GEQVRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGVRRIE 809
Cdd:TIGR00344 607 QILANIPIKVIFMDLDEAKRKGAFALFGEKYvpGEKVRVVSVGDFSVELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIE 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 810 AVAGDAFVEYVCARDNYMRCLCSSLKVKAEDVNGRVETILEELRTTRNEVSSLRSKIAVLKAASLANKATTIDNTRVVVE 889
Cdd:TIGR00344 687 AVTGEAAIEYLNEQEDKLKELADILKVTPNELPKKVERFFEEWKALQKELESLKLKIADQKIDELKDKAETINGVKVLVE 766
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 890 NMGDVDADGLKSAAEYLVDTLEDpaAVILGSSPGDGKVSLVAAFSPGVVKMGIQAGKFVGGIAKLCGGGGGGKPNFAQAG 969
Cdd:TIGR00344 767 VVDAKDMKSLKTMADRLKSKLGS--AIYVLASFAEGKVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQGG 844
|
.
gi 1002279858 970 G 970
Cdd:TIGR00344 845 G 845
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
104-668 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 660.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 104 IRRRFLDFYAARGHKILPSSSLVP-DDPTVFLTIAGMLQFKPIFLGKEPRR-VPCATTSQKCIRTNDIENVGRTSRHQTF 181
Cdd:pfam01411 2 IRQTFLDFFEKKGHTRVPSSPVVPrNDPTLLFTNAGMNQFKPIFLGGVAKPpYNRATNSQKCIRAGDLENVGRTGRHHTF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 182 FEMLGNFSFGDYFKKEAITWAWELTTKEFGLPPERLWISVFQDDDEAFSIWHNEVGVPKERIKRLGEDDNFWTSGATGPC 261
Cdd:pfam01411 82 FEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDDEAGPIWEKIVGGPEERILRFGDKDNFWEMGDTGPC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 262 GPCSEIYYDFYPERGSSDA---DLGDDSRFIEFYNLVFMQYNKKDDGSLEPLKQKNIDTGMGLERMARILQKVPNNYETD 338
Cdd:pfam01411 162 GPCSEIDYDRGEEIGGWDSggtPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLERLVAVLQDVRSNYDTD 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 339 LIFPIIEKAASMALVSYTTaDDAMKTNLKIIGDHMRAVVYLISDGVIPSNIGRGYVVrrlirrvvrtgRLIGIRGDGHG- 417
Cdd:pfam01411 242 VFIPVIELIEEISGARYYT-VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVL-----------RRILRRAVRHAk 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 418 --NSEGAFLPSLAEVAISLSTEIDPDVESRRKSILGELQREELRFVQTLERGEKLLDELLdealssAGNNGGKPCLSGKD 495
Cdd:pfam01411 310 klGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLI------AKLKKGKKTLPGED 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 496 VFLLYDTYGFPVEITAEISGERGVIVDMKGFDMEMENQRKQSQAAHNVVKLSVGNEtEIVKSIPDTEFLGYDSLSATAVV 575
Cdd:pfam01411 384 AFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKGEKLDVS-ALKELPATTEFLGYDDLESEAKI 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 576 KGLLVNGNSVNVVSEGSDVEIFLDRTPFYAESGGQVGDNGFLYVYGEEdakqkavIEINDVQKSlGNIFVHKGTIKQGSV 655
Cdd:pfam01411 463 LALPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIGDGGE-------FRVTDVQKY-GGVVVHKGKLESGKL 534
|
570
....*....|...
gi 1002279858 656 EVGKEIDAAVDAK 668
Cdd:pfam01411 535 KVGDKVIAVIDED 547
|
|
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
102-814 |
4.64e-148 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 453.08 E-value: 4.64e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 102 DAIRRRFLDFYAARGHKILPSSSLVPD-DPTVFLTIAGMLQFKPIFLGkEPRrvPCAT---TSQKCIRTNDIENVGRTSr 177
Cdd:PRK01584 4 DELRKKYIDFFKSKGHVEIAGKSLIPEnDPTVLFTTAGMHPLVPYLLG-EPH--PSGTrlvDVQKCLRTGDIDEVGDLS- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 178 HQTFFEMLGNFSFGDYFKKEAITWAWELTT--KEFGLPPERLWISVFQDDD------EAFSIWHNeVGVPKERIKRLGED 249
Cdd:PRK01584 80 HLTFFEMLGNWSLGAYFKEESIKYSFEFLTspDYLNIPKDKLYVTVFEGDEeiprdeETASVWES-LGIPKDRIFYLSRE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 250 DNFW-TSGATGPCGPCSEIYYDFYPERGSSDADLGDD-SRFIEFYNLVFMQYNKKDDGSLEPLKQKNIDTGMGLERMARI 327
Cdd:PRK01584 159 HNWWgPVGETGPCGPDTEIFVDTGKPKCSVNCRPTCScGKYFEIWNNVFMQYNKDEDGNYEELKRKCVDTGMGIERTIAF 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 328 LQKVPNNYETDLIFPIIEKAASMALVSYTTADDAmKTNLKIIGDHMRAVVYLISD--GVIPSNIGRGYVVRRLIRRVVRT 405
Cdd:PRK01584 239 LQGKSSVYDTEAFTPIIKRIEKISGKIYGQNEED-DRSIRIIADHIRAACFILGDpfVVLPSNVGQGYVLRRLIRRSIRH 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 406 GRLIGIrgdghgnsEGAFLPSLAEVAISLSTEIDPDVESRRKSILGELQREELRFVQTLERGEKLLDELLDEALSSAgnn 485
Cdd:PRK01584 318 AKKLGI--------ESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEFIKLIPNLGSSK--- 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 486 ggkpCLSGKDVFLLYDTYGFPVEITAEISGERGVIVDMKGFDMEMENQRKQSQAahnvvklsvgneteivksipdteflg 565
Cdd:PRK01584 387 ----IIPGDIAFKLYDTYGFPYEITEELASEYGFTVDREGFDEHFKKHQKVSKK-------------------------- 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 566 ydslsatavvkgllvngnsvnvvsegsdveifldrtpfyaesGGQVGDNGFLYVYGEEDAKqkavieindvqkslgnifv 645
Cdd:PRK01584 437 ------------------------------------------GADKVFKGGLADHSYETTK------------------- 455
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 646 hkgtikqgsvevgkeidaavdaklrqgakaHHTATHLLQSALKSIIGSETSQAGSLVAFDRLRFDFNFHRPLSEEELMKI 725
Cdd:PRK01584 456 ------------------------------LHTATHLLHKALRLVLGDHVRQKGSNITAERLRFDFSHPEKMTDDEIKKV 505
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 726 ESLVNQWVSSATHLETKVMDLQDAKNAGAIAMFGEKYGEQVRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGV 805
Cdd:PRK01584 506 EDIVNLQIKNDLSVKKEVMSLEEAREKGAMALFGEKYEDIVKVYEIDGFSKEVCGGPHVENTGELGTFKIQKEQSSSSGV 585
|
....*....
gi 1002279858 806 RRIEAVAGD 814
Cdd:PRK01584 586 RRIRAILID 594
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
102-331 |
3.60e-134 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 402.89 E-value: 3.60e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 102 DAIRRRFLDFYAARGHKILPSSSLVP-DDPTVFLTIAGMLQFKPIFLGKEPRRVPCATTSQKCIRTNDIENVGRTSRHQT 180
Cdd:cd00673 2 SEIRETFLSFFEKKGHTRVPSSPVVPrDDPTLLFTNAGMNQFKPIFLGEVPPPANRLVNSQKCIRAGDIDNVGKTGRHHT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 181 FFEMLGNFSFGDYFKKEAITWAWELTTKEFGLPPERLWISVFQDDDEAFSIWHNEVGVPKERIKRLGEDDNFWTSGATGP 260
Cdd:cd00673 82 FFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGDDEEEAIWWWKIGLPGIRIERIGFKDNFWEMGGNGP 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002279858 261 CGPCSEIYYDFYPERGSSDADLGDDSRFIEFYNLVFMQYNKKDDGSLEPLKQKNIDTGMGLERMARILQKV 331
Cdd:cd00673 162 CGPCSEIFYDRGEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERLVWVLQGV 232
|
|
| A-tRNA_syn_arch |
TIGR03683 |
alanyl-tRNA synthetase; This family of alanyl-tRNA synthetases is limited to the archaea, and ... |
96-987 |
4.22e-127 |
|
alanyl-tRNA synthetase; This family of alanyl-tRNA synthetases is limited to the archaea, and is a subset of those sequences identified by the model pfam07973 covering the second additional domain (SAD) of alanyl and threonyl tRNA synthetases .
Pssm-ID: 274722 [Multi-domain] Cd Length: 902 Bit Score: 407.84 E-value: 4.22e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 96 SGEWSGDAIRRRFLDFYAARGHKILPSSSLVP---DDptVFLTIAGMLQFKP-IFLGKEPrrvPCA---TTSQKCIRTND 168
Cdd:TIGR03683 53 SKKYTLDEMREAFLSFFEKHGHTRIKRYPVVArwrDD--VYLTIASIADFQPwVTSGLVP---PPAnplVISQPCIRLND 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 169 IENVGRTSRHQTFFEMLGNFSFGD-----YFKKEAITWAWELTtKEFGLPPERLwisVFqdddeafsiwhnevgvpKEri 243
Cdd:TIGR03683 128 IDNVGRTGRHLTCFEMMAHHAFNYpdkeiYWKDETVEYCFEFL-EELGIDPEEI---TY-----------------KE-- 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 244 krlgeddNFWTSGatGPCGPCSEIYYdfypeRGssdadlgddsrfIEFYNLVFMQYNKK-------DDGSLEPLKQKNID 316
Cdd:TIGR03683 185 -------SPWEGG--GNAGPCFEVIV-----GG------------LELATLVFMQYEEDkegeieiKGGRYSEMPLKIVD 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 317 TGMGLERMARILQKVPNNYetDLIFP-IIEKAASMALVSYTTaDDAMKTNLKIIG------------------------- 370
Cdd:TIGR03683 239 TGYGLERFVWASQGTPTAY--DAIFPeIVDKLKENAGVELID-EEILAENARLAGmmdiedeedlrelrkkvadkigidv 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 371 -----------------DHMRAVVYLISDGVIPSNIGRGYVVRRLIRRVVRTGRLIGIRGDghgnsegafLPSLAEVAIS 433
Cdd:TIGR03683 316 eelekiiapveriyaiaDHTRCLAFMLGDGIVPSNVKEGYLARLVIRRTLRLMRELGLDIP---------LSDLVEMQLE 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 434 LSTEIDPDVESRRKSILGELQREELRFVQTLERGEKLLdelldealSSAGNNGGKpcLSGKDVFLLYDTYGFPVEITAEI 513
Cdd:TIGR03683 387 ELKKIYPELKENKDYILDILDLEEEKYRETLERGRRIV--------ERLLKTKKE--IPLDDLIELYDSHGIPPEIVKEI 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 514 SGERGVIVDM-KGFD---MEMENQRKQsqaahnvVKLSVGNETEIVKSIPDTEFLGYD---SLSATAVVkgLLVNGNsvn 586
Cdd:TIGR03683 457 AAELGAEVEIpDNFYsivAERHEKEEK-------EEESPKDYEERAKDLPETRRLFYEdptMREFEAKV--LGVFDN--- 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 587 vvsegsdvEIFLDRTPFYAESGGQVGDNGFLYVYGEEdakqkavIEINDVQKsLGNIFVHKgtIKQGSVEVGKEIDAAVD 666
Cdd:TIGR03683 525 --------YVVLDQTAFYPEGGGQPADTGYLITNGGE-------YRVVDVQK-VGGVIVHK--VDGEGIKEGDEVKGEID 586
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 667 AKLRQGAKAHHTATHLLQSALKSIIGSETSQAGSLVAFDRLRFDFNFHRPLSEEELMKIESLVNQWVSSATHLETKVMDL 746
Cdd:TIGR03683 587 WERRLRLMRHHTATHVLLAAARRVLGRHVWQAGAQKDTDKARLDITHYKRISEEEIKEIERLANRIVMENRPVSVKWMDR 666
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 747 QDAKnagaiamfgEKYG-----------EQVRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGVRRIEAVAGDA 815
Cdd:TIGR03683 667 NEAE---------QKYGfrlyqggvppgREIRVVEIEDWDVQACGGTHCRNTGEIGPIKILKTERIQDGVERIEFAAGEA 737
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 816 FVEYVCARDNYMRCLCSSLKVKAEDVNGRVETILEELRTTRNEVSSLRSKIAVLKAASLANKATTIDNTRVVVENMgDVD 895
Cdd:TIGR03683 738 ALEYIQELEDLLRESSDILKVPPEQLPETVKRFFEEWKEQRKEIERLKKKLAELKIYELISEAERIGGVEVIVELV-DAD 816
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 896 ADGLKSAAEYLVDTLedpAAVILGsSPGDGKVSLVAAFSPGVvkmGIQAGKFVGGIAKLCGGGGGGKPNFAQAGGRKPEN 975
Cdd:TIGR03683 817 MDELQEIAEKLAEKG---LVVVLV-SGGGGNGRVVISSGEKA---GVDAGELVREIAKELGGGGGGKPDLAQGGGPDDLN 889
|
970
....*....|..
gi 1002279858 976 LPGALEKARDEI 987
Cdd:TIGR03683 890 VDEALEKIKSFL 901
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
587-814 |
5.60e-33 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 127.62 E-value: 5.60e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 587 VVSEGSDVEIFLDRTPFYAESGGQVGDNGFLYVYGEEdakqkavIEINDVQKSLGNIfVHKGTiKQGSVEVGKEIDAAVD 666
Cdd:COG2872 19 VTAVTEEGGVVLDRTAFYPTGGGQPGDTGTLVWDGKE-------IRVVDVRKEDGEI-VHVLE-GAPLPEVGDEVTGEID 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 667 AKLRQGAKAHHTATHLLQSALKSIIGSETsqAGSLVAFDRLRFDFNFHRPlSEEELMKIESLVNQWVSSATHLETKVMDL 746
Cdd:COG2872 90 WERRYRHMRLHTALHLLSAVVYREYGAPV--TGGQIGEDRARIDFDLPEF-DEEDLEEIEAEANELIAADLPVRIYWITR 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002279858 747 QDA-KNAG----AIAMFGEKYGEqVRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGVRRIEAVAGD 814
Cdd:COG2872 167 EELeAIPGlvrtMSVLPPPGVGR-VRIVEIGGVDLQPCGGTHVANTGEIGRIKITKIEKKGKGNRRVYFTLGE 238
|
|
| a_tRNA_ed_AlaXM |
NF040865 |
alanyl-tRNA editing protein AlaXM; |
585-809 |
5.42e-26 |
|
alanyl-tRNA editing protein AlaXM;
Pssm-ID: 468802 [Multi-domain] Cd Length: 234 Bit Score: 107.31 E-value: 5.42e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 585 VNVVSEGsdveIFLDRTPFYAESGGQVGDNGFLYVYGEEdakqkavIEINDVQKSLGNIfVHKGTiKQGSVEVGKEIDAA 664
Cdd:NF040865 19 VRVKGNG----VVLDRTAFYPTGGGQPHDTGTLVRDDKE-------FRVVDVRKEGGEI-AHVVD-RAPGLKPGDKVKGE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 665 VDAKLRQGAKAHHTATHLLQSALKSIIGSETSqaGSLVAFDRLRFDFNFHRpLSEEELMKIESLVNQWVSSATHLETKVM 744
Cdd:NF040865 86 IDWDRRYRLMRYHTASHILSAVLYREYGALIT--GGQISPDKARVDFSLEN-FDRELLEEIIEEANEIIAEGIEVKIYWL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002279858 745 DLQDAKNAGAIAMFGEKYGEQ---VRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGVRRIE 809
Cdd:NF040865 163 PREEALKIPGLVRLAKRLPPEieeVRIVEIEGVDIQADGGTHVKNTGEIGEIKILKRENKGKGNKRLY 230
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
766-808 |
4.51e-18 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 78.19 E-value: 4.51e-18
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1002279858 766 VRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGVRRI 808
Cdd:smart00863 1 VRVVSIGDFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
766-808 |
1.64e-16 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 74.02 E-value: 1.64e-16
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1002279858 766 VRVVEVPGVSMELCGGTHVSNTAEIRGFKIISEQGIASGVRRI 808
Cdd:pfam07973 1 VRVVSIGDFDVDLCGGTHVPNTGEIGAFKILKGESKNKGLRRI 43
|
|
| DHHA1 |
pfam02272 |
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ... |
845-987 |
3.54e-14 |
|
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domains is also found in alanyl tRNA synthetase, suggesting that this domain may have an RNA binding function. The domain is about 60 residues long and contains a conserved GG motif.
Pssm-ID: 396724 [Multi-domain] Cd Length: 139 Bit Score: 70.55 E-value: 3.54e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 845 VETILEELRTTRNEVSSLRSKIAVLKAASLANKATTIDNTRVVVENMG-DVDADGLKSAAEYLVDTLEDPAAVILGSSPG 923
Cdd:pfam02272 1 LESLNEELKELEKELEELKEALALLKAKELLEKAEEINGVKVLVAEVGeGWDAGALGIAADRLKKKLGDPVIVLVAKEDG 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002279858 924 DgKVSLVAAFSPGVvkmGIQAGKFVGGIAKLCGGGGGGKPnFAQAGGRKPENLPGALEKARDEI 987
Cdd:pfam02272 81 D-KVKVSARSSKDK---GVDAGELLKEVAAILGGGGGGHD-LAAGAGIDAEKLDEALELLEEAI 139
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
593-795 |
1.20e-07 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 53.55 E-value: 1.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 593 DVEIFLDRTPFYAESGGQVGDNGFLyVYGEEDAKqkavIEINDVQKSLGNIFvHKGTIK------QGSVEVGKEIDAAVD 666
Cdd:PLN02961 2 RIALVLDRTIFHPQGGGQPSDTGRI-VISGGDTK----FSVQDVRRKDGVVY-HYGVFEgsnpesASPFEAGDEVTVTVD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 667 AKLRQGAKAHHTATHLLQSALKSiIGSETSQAGSLVAFDRLRF-DFNFHRPLSE-EELMK-IESLVNQWVSSATHLETKV 743
Cdd:PLN02961 76 ESRRKLHSRLHSAGHLLDVCMAR-VGLGPLEPGKGYHFPDGPFvEYKGKIPQGElDSKQDeLEAEANELIAEGGKVSAAV 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1002279858 744 MDLQDAKNA--GAIAMFGEKYGEQ--VRVVEVPGVSmelCGGTHVSNTAEIRGFKI 795
Cdd:PLN02961 155 LPYDEAAELcgGSLPDYIAKDSTPriVKIGDSPGCP---CGGTHVADVSEITSVKV 207
|
|
| ThrS |
COG0441 |
Threonyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Threonyl-tRNA ... |
677-797 |
5.47e-04 |
|
Threonyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Threonyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440210 [Multi-domain] Cd Length: 639 Bit Score: 43.87 E-value: 5.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 677 HTATHLLQSALKSI-------IGSETSQaGslvaFdrlRFDFNFHRPLSEEELMKIESLVNQWVSSATHLETKVMDLQDA 749
Cdd:COG0441 73 HSAAHLLAQAVKRLypdakltIGPVIEN-G----F---YYDFDLERPFTPEDLEKIEKEMKEIIKEDLPIEREEVSREEA 144
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002279858 750 knagaIAMF---GEKYgeQVRVVE-VPG---VSM-------ELCGGTHVSNTAEIRGFKIIS 797
Cdd:COG0441 145 -----IELFkekGEPY--KVELIEdIPEdeeISLyrqgefvDLCRGPHVPSTGKIKAFKLLS 199
|
|
| PRK12444 |
PRK12444 |
threonyl-tRNA synthetase; Reviewed |
675-800 |
1.11e-03 |
|
threonyl-tRNA synthetase; Reviewed
Pssm-ID: 183530 [Multi-domain] Cd Length: 639 Bit Score: 42.81 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002279858 675 AHHTATHLLQSALKSIIGSETSQAGSLVAfDRLRFDFNFHRPLSEEELMKIESLVNQWVSSATHLETKVMDLQDAKnaga 754
Cdd:PRK12444 75 ARHSAAHILAQAVKRLYGDVNLGVGPVIE-NGFYYDMDLPSSVNVEDLRKIEKEMKKIINENIKIERVEVSREEAA---- 149
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1002279858 755 iAMFGEKY-------------GEQVRVVEvPGVSMELCGGTHVSNTAEIRGFKIISEQG 800
Cdd:PRK12444 150 -KLFQEMNdrlklelleaipsGESITLYK-QGEFVDLCRGPHLPSTGYLKAFQLTHVSG 206
|
|
| |
