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Conserved domains on  [gi|1002262668|ref|XP_015635678|]
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uncharacterized protein [Oryza sativa Japonica Group]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11469162)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 135-245 1.31e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.03  E-value: 1.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002262668 135 AVEEEHAEKVAALDAQYKRMMDEQPGDALFLRNYAQFLHEvKGDARRAEEYYSRAMLADPSDGEIMSQYAkLVWEVHRDL 214
Cdd:COG4783    11 AQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQ-LGDLDEAIVLLHEALELDPDEPEARLNLG-LALLKAGDY 88

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1002262668 215 DRSLTYFHKSVQAAPHNSNVLAAYASFLWEQ 245
Cdd:COG4783    89 DEALALLEKALKLDPEHPEAYLRLARAYRAL 119
 
Name Accession Description Interval E-value
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 135-245 1.31e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.03  E-value: 1.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002262668 135 AVEEEHAEKVAALDAQYKRMMDEQPGDALFLRNYAQFLHEvKGDARRAEEYYSRAMLADPSDGEIMSQYAkLVWEVHRDL 214
Cdd:COG4783    11 AQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQ-LGDLDEAIVLLHEALELDPDEPEARLNLG-LALLKAGDY 88

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1002262668 215 DRSLTYFHKSVQAAPHNSNVLAAYASFLWEQ 245
Cdd:COG4783    89 DEALALLEKALKLDPEHPEAYLRLARAYRAL 119
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 148-239 1.49e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002262668 148 DAQYKRMMDEQPGDALFLRNYAQFLHEvkGDARRAEEYYSRAMLADPSDGEIMSQYAKLVWEVhRDLDRSLTYFHKSVQA 227
Cdd:TIGR02917 790 IKHYQTVVKKAPDNAVVLNNLAWLYLE--LKDPRALEYAERALKLAPNIPAILDTLGWLLVEK-GEADRALPLLRKAVNI 866

                          90
                  ....*....|..
gi 1002262668 228 APHNSNVLAAYA 239
Cdd:TIGR02917 867 APEAAAIRYHLA 878
 
Name Accession Description Interval E-value
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 135-245 1.31e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.03  E-value: 1.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002262668 135 AVEEEHAEKVAALDAQYKRMMDEQPGDALFLRNYAQFLHEvKGDARRAEEYYSRAMLADPSDGEIMSQYAkLVWEVHRDL 214
Cdd:COG4783    11 AQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQ-LGDLDEAIVLLHEALELDPDEPEARLNLG-LALLKAGDY 88

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1002262668 215 DRSLTYFHKSVQAAPHNSNVLAAYASFLWEQ 245
Cdd:COG4783    89 DEALALLEKALKLDPEHPEAYLRLARAYRAL 119
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
149-245 2.57e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.53  E-value: 2.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002262668 149 AQYKRMMDEQPGDALFLRNYAQFLHEvKGDARRAEEYYSRAMLADPSDGEIMSQYAkLVWEVHRDLDRSLTYFHKSVQAA 228
Cdd:COG0457    63 ADYEQALELDPDDAEALNNLGLALQA-LGRYEEALEDYDKALELDPDDAEALYNLG-LALLELGRYDEAIEAYERALELD 140

                          90
                  ....*....|....*..
gi 1002262668 229 PHNSNVLAAYASFLWEQ 245
Cdd:COG0457   141 PDDADALYNLGIALEKL 157
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 149-245 4.56e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 4.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002262668 149 AQYKRMMDEQPGDALFLRNYAQfLHEVKGDARRAEEYYSRAMLADPSDGEIMSQYAKLvWEVHRDLDRSLTYFHKSVQAA 228
Cdd:COG2956    97 ELLEKLLELDPDDAEALRLLAE-IYEQEGDWEKAIEVLERLLKLGPENAHAYCELAEL-YLEQGDYDEAIEALEKALKLD 174

                          90
                  ....*....|....*..
gi 1002262668 229 PHNSNVLAAYASFLWEQ 245
Cdd:COG2956   175 PDCARALLLLAELYLEQ 191
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 149-245 6.69e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.83  E-value: 6.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002262668 149 AQYKRMMDEQPGDALFLRNYAQfLHEVKGDARRAEEYYSRAMLADPSDGEIMSQYAKLVWEVHrDLDRSLTYFHKSVQAA 228
Cdd:COG4235     4 ARLRQALAANPNDAEGWLLLGR-AYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAG-DTEEAEELLERALALD 81

                          90
                  ....*....|....*..
gi 1002262668 229 PHNSNVLAAYASFLWEQ 245
Cdd:COG4235    82 PDNPEALYLLGLAAFQQ 98
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
149-229 1.06e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.46  E-value: 1.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002262668 149 AQYKRMMDEQPGDALFLRNYAQFLHEvKGDARRAEEyYSRAMLADPSDGEIMSQYAKLVWEVhRDLDRSLTYFHKSVQAA 228
Cdd:COG3063    13 EYYEKALELDPDNADALNNLGLLLLE-QGRYDEAIA-LEKALKLDPNNAEALLNLAELLLEL-GDYDEALAYLERALELD 89


                  .
gi 1002262668 229 P 229
Cdd:COG3063    90 P 90
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 145-245 1.14e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.79  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002262668 145 AALDAQYKRMMDEQPGDALFLRNYAQFLHEVKGDARRAEEYYSRAMLADPSDGEIMSQYAkLVWEVHRDLDRSLTYFHKS 224
Cdd:COG5010    36 NTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLA-LLYSRSGDKDEAKEYYEKA 114

                          90       100
                  ....*....|....*....|.
gi 1002262668 225 VQAAPHNSNVLAAYASFLWEQ 245
Cdd:COG5010   115 LALSPDNPNAYSNLAALLLSL 135
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 148-239 1.49e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002262668 148 DAQYKRMMDEQPGDALFLRNYAQFLHEvkGDARRAEEYYSRAMLADPSDGEIMSQYAKLVWEVhRDLDRSLTYFHKSVQA 227
Cdd:TIGR02917 790 IKHYQTVVKKAPDNAVVLNNLAWLYLE--LKDPRALEYAERALKLAPNIPAILDTLGWLLVEK-GEADRALPLLRKAVNI 866

                          90
                  ....*....|..
gi 1002262668 228 APHNSNVLAAYA 239
Cdd:TIGR02917 867 APEAAAIRYHLA 878
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
172-245 1.50e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.07  E-value: 1.50e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002262668 172 LHEVKGDARRAEEYYSRAMLADPSDGEIMSQYAkLVWEVHRDLDRSLTyFHKSVQAAPHNSNVLAAYASFLWEQ 245
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLG-LLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLEL 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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