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Conserved domains on  [gi|1002248420|ref|XP_015628393|]
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ankyrin repeat domain-containing protein 2A [Oryza sativa Japonica Group]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
230-347 8.19e-28

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 110.04  E-value: 8.19e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVA 309
Cdd:COG0666    91 LHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVK 170

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1002248420 310 LLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLLEKH 347
Cdd:COG0666   171 LLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEA 208
STI1 super family cl17974
STI1 domain; This entry corresponds to the STI1 domain that is found in two copies in the Sti1 ...
 143-196 1.54e-06

STI1 domain; This entry corresponds to the STI1 domain that is found in two copies in the Sti1 protein.


The actual alignment was detected with superfamily member pfam17830:

Pssm-ID: 450205  Cd Length: 55  Bit Score: 44.86  E-value: 1.54e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1002248420 143 NPAHKEQLEA--RIARMKDDPSLKPILDEIENGgPAAMMKYWNDPEALQKFGRAMG 196
Cdd:pfam17830   1 DPELLAKLAAnpETRALLSDPEFVAKLQQIQKN-PSSLQQYMQDPRVMTKLGVLMG 55
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
230-347 8.19e-28

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 110.04  E-value: 8.19e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVA 309
Cdd:COG0666    91 LHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVK 170

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1002248420 310 LLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLLEKH 347
Cdd:COG0666   171 LLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEA 208
Ank_2 pfam12796
Ankyrin repeats (3 copies);
230-322 6.65e-18

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 77.46  E-value: 6.65e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEaGAAVDAVDkNKNTALHYAAGYGRKDCVA 309
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLE-HADVNLKD-NGRTALHYAARSGHLEIVK 78

                          90
                  ....*....|...
gi 1002248420 310 LLLDHGAAVTVQN 322
Cdd:pfam12796  79 LLLEKGADINVKD 91
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 230-340 8.28e-13

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 68.84  E-value: 8.28e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVA 309
Cdd:PHA02874  128 LHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIK 207

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1002248420 310 LLLDHGAAVTVQNLDGKTAIDVAKLNNQEEV 340
Cdd:PHA02874  208 LLIDHGNHIMNKCKNGFTPLHNAIIHNRSAI 238
STI1 pfam17830
STI1 domain; This entry corresponds to the STI1 domain that is found in two copies in the Sti1 ...
 143-196 1.54e-06

STI1 domain; This entry corresponds to the STI1 domain that is found in two copies in the Sti1 protein.


Pssm-ID: 436075  Cd Length: 55  Bit Score: 44.86  E-value: 1.54e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1002248420 143 NPAHKEQLEA--RIARMKDDPSLKPILDEIENGgPAAMMKYWNDPEALQKFGRAMG 196
Cdd:pfam17830   1 DPELLAKLAAnpETRALLSDPEFVAKLQQIQKN-PSSLQQYMQDPRVMTKLGVLMG 55
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 291-320 5.80e-05

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 39.49  E-value: 5.80e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 1002248420  291 NKNTALHYAAGYGRKDCVALLLDHGAAVTV 320
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
230-347 8.19e-28

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 110.04  E-value: 8.19e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVA 309
Cdd:COG0666    91 LHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVK 170

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1002248420 310 LLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLLEKH 347
Cdd:COG0666   171 LLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEA 208
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
228-348 4.92e-26

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 105.42  E-value: 4.92e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 228 SVIHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDC 307
Cdd:COG0666   122 TPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEI 201

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1002248420 308 VALLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLLEKHA 348
Cdd:COG0666   202 VKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAG 242
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
230-348 1.49e-18

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 84.62  E-value: 1.49e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVA 309
Cdd:COG0666   157 LHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVK 236

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1002248420 310 LLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLLEKHA 348
Cdd:COG0666   237 LLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLAL 275
Ank_2 pfam12796
Ankyrin repeats (3 copies);
230-322 6.65e-18

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 77.46  E-value: 6.65e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEaGAAVDAVDkNKNTALHYAAGYGRKDCVA 309
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLE-HADVNLKD-NGRTALHYAARSGHLEIVK 78

                          90
                  ....*....|...
gi 1002248420 310 LLLDHGAAVTVQN 322
Cdd:pfam12796  79 LLLEKGADINVKD 91
Ank_2 pfam12796
Ankyrin repeats (3 copies);
263-344 6.79e-17

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 74.77  E-value: 6.79e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 263 LHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLLDHgAAVTVQNlDGKTAIDVAKLNNQEEVLK 342
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIVK 78


                  ..
gi 1002248420 343 LL 344
Cdd:pfam12796  79 LL 80
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 230-340 8.28e-13

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 68.84  E-value: 8.28e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVA 309
Cdd:PHA02874  128 LHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIK 207

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1002248420 310 LLLDHGAAVTVQNLDGKTAIDVAKLNNQEEV 340
Cdd:PHA02874  208 LLIDHGNHIMNKCKNGFTPLHNAIIHNRSAI 238
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
230-347 1.59e-12

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 67.29  E-value: 1.59e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVA 309
Cdd:COG0666    25 LLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVK 104

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1002248420 310 LLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLLEKH 347
Cdd:COG0666   105 LLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEA 142
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 232-326 6.12e-12

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 66.85  E-value: 6.12e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 232 HTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALL 311
Cdd:PTZ00322   88 QLAASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLL 167

                          90       100
                  ....*....|....*....|..
gi 1002248420 312 LDH-------GAAVTVQNLDGK 326
Cdd:PTZ00322  168 SRHsqchfelGANAKPDSFTGK 189
Ank_4 pfam13637
Ankyrin repeats (many copies);
259-312 8.47e-11

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 56.90  E-value: 8.47e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1002248420 259 GRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLL 312
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 275-347 4.37e-10

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 61.07  E-value: 4.37e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002248420 275 AQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLLEKH 347
Cdd:PTZ00322   98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRH 170
Ank_4 pfam13637
Ankyrin repeats (many copies);
293-344 5.55e-10

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 54.59  E-value: 5.55e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1002248420 293 NTALHYAAGYGRKDCVALLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLL 344
Cdd:pfam13637   2 LTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 233-348 1.60e-09

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 58.91  E-value: 1.60e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 233 TASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFA--CGYGELKCAQVLLEAGAAVDA----------------VDKNKNT 294
Cdd:PHA03100  115 SKKSNSYSIVEYLLDNGANVNIKNSDGENLLHLYleSNKIDLKILKLLIDKGVDINAknrvnyllsygvpiniKDVYGFT 194

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1002248420 295 ALHYAAGYGRKDCVALLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLLEKHA 348
Cdd:PHA03100  195 PLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNG 248
Ank_5 pfam13857
Ankyrin repeats (many copies);
278-332 6.33e-09

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 51.58  E-value: 6.33e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1002248420 278 LLEAG-AAVDAVDKNKNTALHYAAGYGRKDCVALLLDHGAAVTVQNLDGKTAIDVA 332
Cdd:pfam13857   1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 234-344 1.33e-08

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 56.41  E-value: 1.33e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 234 ASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTAL----------------H 297
Cdd:PLN03192  533 ASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALwnaisakhhkifrilyH 612

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002248420 298 YAA-------------GYGRKDCVAL--LLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLL 344
Cdd:PLN03192  613 FASisdphaagdllctAAKRNDLTAMkeLLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLL 674
PHA03095 PHA03095
ankyrin-like protein; Provisional
 242-336 2.75e-08

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 55.03  E-value: 2.75e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 242 LKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQV--LLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLLDHGAAVT 319
Cdd:PHA03095  205 VRELIRAGCDPAATDMLGNTPLHSMATGSSCKRSLVlpLLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIALGADIN 284

                          90
                  ....*....|....*..
gi 1002248420 320 VQNLDGKTAIDVAKLNN 336
Cdd:PHA03095  285 AVSSDGNTPLSLMVRNN 301
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 271-342 3.43e-08

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 55.07  E-value: 3.43e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002248420 271 ELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLK 342
Cdd:PHA02876  157 ELLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIK 228
PHA03095 PHA03095
ankyrin-like protein; Provisional
 238-344 3.89e-08

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 54.65  E-value: 3.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 238 DVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQV---LLEAGAAVDAVDKNKNTALHYAAGYG-RKDCVALLLD 313
Cdd:PHA03095   26 TVEEVRRLLAAGADVNFRGEYGKTPLHLYLHYSSEKVKDIvrlLLEAGADVNAPERCGFTPLHLYLYNAtTLDVIKLLIK 105

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1002248420 314 HGAAVTVQNLDGKTAIDV--AKLNNQEEVLKLL 344
Cdd:PHA03095  106 AGADVNAKDKVGRTPLHVylSGFNINPKVIRLL 138
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 240-347 9.03e-08

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 53.43  E-value: 9.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 240 EGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLLDHGAAVT 319
Cdd:PHA02874  105 DMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYAN 184

                          90       100
                  ....*....|....*....|....*...
gi 1002248420 320 VQNLDGKTAIDVAKLNNQEEVLKLLEKH 347
Cdd:PHA02874  185 VKDNNGESPLHNAAEYGDYACIKLLIDH 212
PHA03095 PHA03095
ankyrin-like protein; Provisional
 232-344 1.28e-07

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 53.10  E-value: 1.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 232 HTASVGDVEGLKKALEEGVDKDEEDSEGRRGLH-FACGYGELKCAQVLLEAGAAVDAVDKNKNTALH-YAAGYG-RKDCV 308
Cdd:PHA03095   56 HYSSEKVKDIVRLLLEAGADVNAPERCGFTPLHlYLYNATTLDVIKLLIKAGADVNAKDKVGRTPLHvYLSGFNiNPKVI 135

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1002248420 309 ALLLDHGAAVTVQNLDGKTAIDVA-KLNNQE-EVLKLL 344
Cdd:PHA03095  136 RLLLRKGADVNALDLYGMTPLAVLlKSRNANvELLRLL 173
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 238-347 1.99e-07

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 52.57  E-value: 1.99e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 238 DVEGLKKALEEGVDKDEED-SEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLLDHGA 316
Cdd:PHA02878  146 EAEITKLLLSYGADINMKDrHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGA 225

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1002248420 317 AVTVQNLDGKTA--IDVAKLNNQeEVLKLLEKH 347
Cdd:PHA02878  226 STDARDKCGNTPlhISVGYCKDY-DILKLLLEH 257
Ank_2 pfam12796
Ankyrin repeats (3 copies);
296-350 6.25e-07

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 47.03  E-value: 6.25e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1002248420 296 LHYAAGYGRKDCVALLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLLEKHAFV 350
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADV 55
STI1 pfam17830
STI1 domain; This entry corresponds to the STI1 domain that is found in two copies in the Sti1 ...
 143-196 1.54e-06

STI1 domain; This entry corresponds to the STI1 domain that is found in two copies in the Sti1 protein.


Pssm-ID: 436075  Cd Length: 55  Bit Score: 44.86  E-value: 1.54e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1002248420 143 NPAHKEQLEA--RIARMKDDPSLKPILDEIENGgPAAMMKYWNDPEALQKFGRAMG 196
Cdd:pfam17830   1 DPELLAKLAAnpETRALLSDPEFVAKLQQIQKN-PSSLQQYMQDPRVMTKLGVLMG 55
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 278-348 3.06e-06

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 49.10  E-value: 3.06e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002248420 278 LLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLLEKHA 348
Cdd:PLN03192  544 LLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRILYHFA 614
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 228-316 3.23e-06

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 48.45  E-value: 3.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 228 SVIHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKN-TALHYAAGYGRKD 306
Cdd:PHA02875  137 SPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCvAALCYAIENNKID 216

                          90
                  ....*....|
gi 1002248420 307 CVALLLDHGA 316
Cdd:PHA02875  217 IVRLFIKRGA 226
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
231-329 4.62e-06

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 47.64  E-value: 4.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 231 HHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVAL 310
Cdd:COG0666   191 HLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKL 270

                          90
                  ....*....|....*....
gi 1002248420 311 LLDHGAAVTVQNLDGKTAI 329
Cdd:COG0666   271 LLLALLLLAAALLDLLTLL 289
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 228-344 4.63e-06

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 48.34  E-value: 4.63e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 228 SVIHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRK-D 306
Cdd:PHA02878  170 TALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYCKDyD 249

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1002248420 307 CVALLLDHGAAVTVQN-LDGKTAIDVAKlnNQEEVLKLL 344
Cdd:PHA02878  250 ILKLLLEHGVDVNAKSyILGLTALHSSI--KSERKLKLL 286
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 230-350 5.73e-06

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 48.14  E-value: 5.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFA-CGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRK-DC 307
Cdd:PHA02876  379 IHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFAlCGTNPYMSVKTLIDRGANVNSKNKDLSTPLHYACKKNCKlDV 458

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1002248420 308 VALLLDHGAAVTVQNldgktaidvakLNNQEEVLKLLEKHAFV 350
Cdd:PHA02876  459 IEMLLDNGADVNAIN-----------IQNQYPLLIALEYHGIV 490
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 230-344 9.80e-06

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 47.37  E-value: 9.80e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGL-KKALEEGVDKDEEDSEGRRGLHFACGYG-ELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGR-KD 306
Cdd:PHA02876  277 LHHASQAPSLSRLvPKLLERGADVNAKNIKGETPLYLMAKNGyDTENIRTLIMLGADVNAADRLYITPLHQASTLDRnKD 356

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1002248420 307 CVALLLDHGAAVTVQNLDGKTAIDVAKLNNQEEVLKLL 344
Cdd:PHA02876  357 IVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTL 394
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 291-322 1.05e-05

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 41.89  E-value: 1.05e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1002248420 291 NKNTALHYAAG-YGRKDCVALLLDHGAAVTVQN 322
Cdd:pfam00023   1 DGNTPLHLAAGrRGNLEIVKLLLSKGADVNARD 33
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 242-347 1.10e-05

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 46.97  E-value: 1.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 242 LKKALEEGVDKDEEDSEGRRGLHFACGYG-----ELKCAQVLLEAGAAVDAVDKNKNTALHYAAGY--GRKDCVALLLDH 314
Cdd:PHA03100   51 VKILLDNGADINSSTKNNSTPLHYLSNIKynltdVKEIVKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEYLLDN 130

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1002248420 315 GAAVTVQNLDGKTAIDVA-KLNNQE-EVLKLLEKH 347
Cdd:PHA03100  131 GANVNIKNSDGENLLHLYlESNKIDlKILKLLIDK 165
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 230-348 1.54e-05

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 46.50  E-value: 1.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAG--------------------------- 282
Cdd:PHA02874  161 IHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLLIDHGnhimnkckngftplhnaiihnrsaiel 240

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002248420 283 ----AAVDAVDKNKNTALHYAAGYG-RKDCVALLLDHGAAVTVQNLDGKTAIDVA-KLNNQEEVLKLLEKHA 348
Cdd:PHA02874  241 linnASINDQDIDGSTPLHHAINPPcDIDIIDILLYHKADISIKDNKGENPIDTAfKYINKDPVIKDIIANA 312
Ank_5 pfam13857
Ankyrin repeats (many copies);
255-299 3.75e-05

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 40.79  E-value: 3.75e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1002248420 255 EDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYA 299
Cdd:pfam13857  12 LDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 291-320 5.80e-05

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 39.49  E-value: 5.80e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 1002248420  291 NKNTALHYAAGYGRKDCVALLLDHGAAVTV 320
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 228-332 7.41e-05

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 44.49  E-value: 7.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 228 SVIHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGY-GELKCAQVLLEAGAAVDAVDKNKN-TALHYAAGYGRK 305
Cdd:PHA02878  203 SPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYcKDYDILKLLLEHGVDVNAKSYILGlTALHSSIKSERK 282

                          90       100
                  ....*....|....*....|....*..
gi 1002248420 306 dcVALLLDHGAAVTVQNLDGKTAIDVA 332
Cdd:PHA02878  283 --LKLLLEYGADINSLNSYKLTPLSSA 307
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 246-344 1.92e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 43.13  E-value: 1.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 246 LEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYA-AGYGRKDCVALLLDHGAAVTVQNLD 324
Cdd:PHA02876  362 LELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFAlCGTNPYMSVKTLIDRGANVNSKNKD 441

                          90       100
                  ....*....|....*....|.
gi 1002248420 325 GKTAIDVA-KLNNQEEVLKLL 344
Cdd:PHA02876  442 LSTPLHYAcKKNCKLDVIEML 462
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 238-347 2.08e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 43.06  E-value: 2.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 238 DVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGA-AVDAVDKNKNTALHYAAGYGRKDCVALLLDHGA 316
Cdd:PHA02875   47 DSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEELLDLGKfADDVFYKDGMTPLHLATILKKLDIMKLLIARGA 126

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1002248420 317 AVTVQNLDGKTAIDVAKLNNQEEVLKLLEKH 347
Cdd:PHA02875  127 DPDIPNTDKFSPLHLAVMMGDIKGIELLIDH 157
Ank_3 pfam13606
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 291-318 2.56e-04

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.


Pssm-ID: 463933 [Multi-domain]  Cd Length: 30  Bit Score: 37.62  E-value: 2.56e-04
                          10        20
                  ....*....|....*....|....*...
gi 1002248420 291 NKNTALHYAAGYGRKDCVALLLDHGAAV 318
Cdd:pfam13606   1 DGNTPLHLAARNGRLEIVKLLLENGADI 28
Ank_4 pfam13637
Ankyrin repeats (many copies);
228-279 2.97e-04

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 38.41  E-value: 2.97e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1002248420 228 SVIHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLL 279
Cdd:pfam13637   3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 246-318 5.79e-04

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 41.57  E-value: 5.79e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002248420 246 LEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLLDHGAAV 318
Cdd:PHA03100  179 LSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSI 251
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 230-346 1.13e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 40.74  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 230 IHHTASVGDVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVA 309
Cdd:PHA02875  106 LHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICK 185

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1002248420 310 LLLDHGAAVTVQNLDGK-TAIDVAKLNNQEEVLKLLEK 346
Cdd:PHA02875  186 MLLDSGANIDYFGKNGCvAALCYAIENNKIDIVRLFIK 223
PHA02917 PHA02917
ankyrin-like protein; Provisional
 258-347 2.32e-03

ankyrin-like protein; Provisional


Pssm-ID: 165231 [Multi-domain]  Cd Length: 661  Bit Score: 39.98  E-value: 2.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 258 EGRRGLHFACGYgeLKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLLDHGAAVTVQNLDGKTAIDVAKLNNQ 337
Cdd:PHA02917  420 KGLCDMSYACPI--LSTINICLPYLKDINMIDKRGETLLHKAVRYNKQSLVSLLLESGSDVNIRSNNGYTCIAIAINESR 497

                          90
                  ....*....|.
gi 1002248420 338 E-EVLKLLEKH 347
Cdd:PHA02917  498 NiELLKMLLCH 508
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 246-329 2.85e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 39.66  E-value: 2.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 246 LEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLLDHGAAVTVQNLDG 325
Cdd:PHA02876  165 LEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNINKNDLSL 244


                  ....
gi 1002248420 326 KTAI 329
Cdd:PHA02876  245 LKAI 248
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 271-329 5.48e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 38.51  E-value: 5.48e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 271 ELKCAQVLLEAGAAVDAVDKNKNTALHYAAGY-GRKDCVALLLDHGAAVTVQNLDGKTAI 329
Cdd:PHA02876  252 DLETSLLLYDAGFSVNSIDDCKNTPLHHASQApSLSRLVPKLLERGADVNAKNIKGETPL 311
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 238-318 8.26e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 38.12  E-value: 8.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 238 DVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQV-LLEAGAAVDAVDKNKNTALHYAAGYGRKDCVALLLDHGA 316
Cdd:PHA02876  320 DTENIRTLIMLGADVNAADRLYITPLHQASTLDRNKDIVItLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGA 399


                  ..
gi 1002248420 317 AV 318
Cdd:PHA02876  400 DI 401
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 263-290 8.80e-03

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 33.42  E-value: 8.80e-03
                          10        20
                  ....*....|....*....|....*....
gi 1002248420 263 LHFACG-YGELKCAQVLLEAGAAVDAVDK 290
Cdd:pfam00023   6 LHLAAGrRGNLEIVKLLLSKGADVNARDK 34
PHA02946 PHA02946
ankyin-like protein; Provisional
 238-318 9.77e-03

ankyin-like protein; Provisional


Pssm-ID: 165256 [Multi-domain]  Cd Length: 446  Bit Score: 37.73  E-value: 9.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002248420 238 DVEGLKKALEEGVDKDEEDSEGRRGLHFACGYGELKCAQVLLEAGAAVDAVDKNKNTALHYAAGYGRK--DCVALLLDHG 315
Cdd:PHA02946   51 DERFVEELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDEviERINLLVQYG 130


                  ...
gi 1002248420 316 AAV 318
Cdd:PHA02946  131 AKI 133
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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