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Conserved domains on  [gi|1001849807|gb|AMM17047|]
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epimerase [Burkholderia sp. PAMC 28687]

Protein Classification

sugar phosphate isomerase/epimerase family protein( domain architecture ID 11437618)

sugar phosphate isomerase/epimerase family protein belonging to the TIM alpha/beta barrel superfamily, similar to Bacillus subtilis inosose isomerase

CATH:  3.20.20.150
Gene Ontology:  GO:0016853|GO:0003824
PubMed:  11257493|12206759

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YcjR COG1082
Sugar phosphate isomerase/epimerase [Carbohydrate transport and metabolism];
3-245 1.60e-46

Sugar phosphate isomerase/epimerase [Carbohydrate transport and metabolism];


:

Pssm-ID: 440699 [Multi-domain]  Cd Length: 254  Bit Score: 156.71  E-value: 1.60e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807   3 KLGVHALVWAGDltpeSTRKVISQTKAAGFDLVELSLHGPKVMDLSLTRDLLQEHGLEIgcsRGLTFDADVSSDDPAAVS 82
Cdd:COG1082     2 KLGLSTYSLPDL----DLEEALRAAAELGYDGVELAGGDLDEADLAELRAALADHGLEI---SSLHAPGLNLAPDPEVRE 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  83 RGLALLEEGVSITAELGGNYFggILYGAMAKYSAPITPQGRRHAVDSLKRIADFALKKGVTLGLEVvnrYESNLLNTASQ 162
Cdd:COG1082    75 AALERLKRAIDLAAELGAKVV--VVHPGSPPPPDLPPEEAWDRLAERLRELAELAEEAGVTLALEN---HEGTFVNTPEE 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 163 ALDMLDEVDAPNVVVHLDTYHMNIEESDFMQPVLACGKRLGYVHIGESN---RGYLGSGTIDFAQFFHALAMIDYKGVVT 239
Cdd:COG1082   150 ALRLLEAVDSPNVGLLLDTGHALLAGEDPVELLRKLGDRIKHVHLKDADgdqHLPPGEGDIDFAAILRALKEAGYDGWLS 229


                  ....*.
gi 1001849807 240 FESFSS 245
Cdd:COG1082   230 LEVESD 235
 
Name Accession Description Interval E-value
YcjR COG1082
Sugar phosphate isomerase/epimerase [Carbohydrate transport and metabolism];
3-245 1.60e-46

Sugar phosphate isomerase/epimerase [Carbohydrate transport and metabolism];


Pssm-ID: 440699 [Multi-domain]  Cd Length: 254  Bit Score: 156.71  E-value: 1.60e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807   3 KLGVHALVWAGDltpeSTRKVISQTKAAGFDLVELSLHGPKVMDLSLTRDLLQEHGLEIgcsRGLTFDADVSSDDPAAVS 82
Cdd:COG1082     2 KLGLSTYSLPDL----DLEEALRAAAELGYDGVELAGGDLDEADLAELRAALADHGLEI---SSLHAPGLNLAPDPEVRE 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  83 RGLALLEEGVSITAELGGNYFggILYGAMAKYSAPITPQGRRHAVDSLKRIADFALKKGVTLGLEVvnrYESNLLNTASQ 162
Cdd:COG1082    75 AALERLKRAIDLAAELGAKVV--VVHPGSPPPPDLPPEEAWDRLAERLRELAELAEEAGVTLALEN---HEGTFVNTPEE 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 163 ALDMLDEVDAPNVVVHLDTYHMNIEESDFMQPVLACGKRLGYVHIGESN---RGYLGSGTIDFAQFFHALAMIDYKGVVT 239
Cdd:COG1082   150 ALRLLEAVDSPNVGLLLDTGHALLAGEDPVELLRKLGDRIKHVHLKDADgdqHLPPGEGDIDFAAILRALKEAGYDGWLS 229


                  ....*.
gi 1001849807 240 FESFSS 245
Cdd:COG1082   230 LEVESD 235
AP_endonuc_2 pfam01261
Xylose isomerase-like TIM barrel; This TIM alpha/beta barrel structure is found in xylose ...
 28-262 1.15e-40

Xylose isomerase-like TIM barrel; This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.


Pssm-ID: 426164 [Multi-domain]  Cd Length: 248  Bit Score: 141.35  E-value: 1.15e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  28 KAAGFDLVELSLHGPKVMDLSLT-----RDLLQEHGLEIgCSRGLTFDADVSSDDPAAVSRGLALLEEGVSITAELGGNY 102
Cdd:pfam01261   5 AELGFDGVELFTRRWFRPPLSDEeaeelKAALKEHGLEI-VVHAPYLGDNLASPDEEEREKAIDRLKRAIELAAALGAKL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 103 FGgILYGAMAKYSAPitpQGRRHAVDSLKRIADFALKKGVTLGLEVVNRYESNLLNTASQALDMLDEVDAPNVVVHLDTY 182
Cdd:pfam01261  84 VV-FHPGSDLGDDPE---EALARLAESLRELADLAEREGVRLALEPLAGKGTNVGNTFEEALEIIDEVDSPNVGVCLDTG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 183 HMNI-EESDFMQPVLAcGKRLGYVHI---------GESNRGYLGSGTIDFAQFFHALAMIDYKGVVTFESFSSTVVNEQL 252
Cdd:pfam01261 160 HLFAaGDGDLFELRLG-DRYIGHVHLkdsknplgsGPDRHVPIGEGVIDFEALFRALKEIGYDGPLSLETFNDGPPEEGA 238

                         250
                  ....*....|
gi 1001849807 253 SNALAIWRNL 262
Cdd:pfam01261 239 REGLEWLREL 248
keto_glucon_epim_IolO NF041099
5-keto-L-gluconate epimerase;
8-241 1.84e-40

5-keto-L-gluconate epimerase;


Pssm-ID: 469025  Cd Length: 269  Bit Score: 141.37  E-value: 1.84e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807   8 ALVWAGDLtpestRKVISQTKAAGFDLVELSLHGPKVMDLSLTRDLLQEHGLEIgcsrgltfdadvssddpAAVSRGLAL 87
Cdd:NF041099   16 ALAFKGDL-----EKGIEKAKKLGYDAVEIAIRDPKLVDVNELKGLLYELNLPV-----------------VAIGTGQAY 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  88 LEEGVSIT-----------------AELGGNYFGGILYGAM-AKYSAPITPQGRRHAVDSLKRIADFALKKGVTLGLEVV 149
Cdd:NF041099   74 LAEGLSLTdpdenirkkaierlkkhIDFASIFGAKVIIGLIrGKKEGRAEEEAEKLFVESMKELADYAEKKGVELVIEPL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 150 NRYESNLLNTASQALDMLDEVDAPNVVVHLDTYHMNIEESDFMQPVLACGKRLGYVHIGESNRGYLGSGTIDFAQFFHAL 229
Cdd:NF041099  154 NRYETDFINTIHEALEVIRKLNRPNVGILADTFHMNIEEPNIEESLRKCGDKLYHFHVADSNRWAPGYGHIDFDSIVKTL 233

                         250
                  ....*....|..
gi 1001849807 230 AMIDYKGVVTFE 241
Cdd:NF041099  234 KEIGYNGAVSVE 245
PRK13209 PRK13209
L-ribulose-5-phosphate 3-epimerase;
18-270 4.33e-13

L-ribulose-5-phosphate 3-epimerase;


Pssm-ID: 237307  Cd Length: 283  Bit Score: 68.09  E-value: 4.33e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  18 ESTRKVISQTKAAGFDLVELS----------LHGPKVMDLSLtRDLLQEHGLEIGcsrGLTFDAD----VSSDDPAAVSR 83
Cdd:PRK13209   21 ECWLEKLAIAKTAGFDFVEMSvdesderlarLDWSREQRLAL-VNALVETGFRVN---SMCLSAHrrfpLGSEDDAVRAQ 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  84 GLALLEEGVSITAELGgnyfggILYGAMAKYSA---PITPQGRRHAVDSLKRIADFALKKGVTLGLEVVNRyesNLLNTA 160
Cdd:PRK13209   97 ALEIMRKAIQLAQDLG------IRVIQLAGYDVyyeQANNETRRRFIDGLKESVELASRASVTLAFEIMDT---PFMNSI 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 161 SQALDMLDEVDAPNVVVHLDTYHMNIEESDFMQPVLACGKRLGYVHI-----GESNRGYLGSGTIDFAQFFHALAMIDYK 235
Cdd:PRK13209  168 SKALGYAHYLNSPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAFHVkdtkpGVFKNVPFGEGVVDFERCFKTLKQSGYC 247

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1001849807 236 GVVTFESFSSTVV--NEQLSNAlaiwRNLWEDSMDLA 270
Cdd:PRK13209  248 GPYLIEMWSETAEdpAAEVAKA----RDFVKARMAEA 280
AP2Ec cd00019
AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester ...
 12-238 2.77e-08

AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of D-arabino-6-hexulose 3-phosphate to D-fructose 6-phosphate, via cleaving the phosphoesterbond with the sugar.


Pssm-ID: 237986  Cd Length: 279  Bit Score: 53.86  E-value: 2.77e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  12 AGDLTPESTRKVISQTKAAGFDLVELSLHGPkvmDLSLTRDLLQEH--GLEIGCSRGLTFDADV--------SSDDPAAV 81
Cdd:cd00019     4 HVSAAGFGLENALKRAKEIGFDTVAMFLGNP---RSWLSRPLKKERaeKFKAIAEEGPSICLSVhapylinlASPDKEKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  82 SRGLALLEEGVSITAELGGNYFGgILYGAMAKYSapiTPQGRRHAVDSLKRIADFALKKGVTLGLEVVNRYESNLLNTAS 161
Cdd:cd00019    81 EKSIERLKDEIERCEELGIRLLV-FHPGSYLGQS---KEEGLKRVIEALNELIDKAETKGVVIALETMAGQGNEIGSSFE 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 162 QALDMLDEVDA-PNVVVHLDTYHM-----NIEESDFMQPVLACG------KRLGYVHIGESNRGY---------LGSGTI 220
Cdd:cd00019   157 ELKEIIDLIKEkPRVGVCIDTCHIfaagyDISTVEGFEKVLEEFdkviglEYLKAIHLNDSKGELgsgkdrhepIGEGDI 236

                         250
                  ....*....|....*...
gi 1001849807 221 DFAQFFHALAMIDYKGVV 238
Cdd:cd00019   237 DGEELFKELKKDPYQNIP 254
 
Name Accession Description Interval E-value
YcjR COG1082
Sugar phosphate isomerase/epimerase [Carbohydrate transport and metabolism];
3-245 1.60e-46

Sugar phosphate isomerase/epimerase [Carbohydrate transport and metabolism];


Pssm-ID: 440699 [Multi-domain]  Cd Length: 254  Bit Score: 156.71  E-value: 1.60e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807   3 KLGVHALVWAGDltpeSTRKVISQTKAAGFDLVELSLHGPKVMDLSLTRDLLQEHGLEIgcsRGLTFDADVSSDDPAAVS 82
Cdd:COG1082     2 KLGLSTYSLPDL----DLEEALRAAAELGYDGVELAGGDLDEADLAELRAALADHGLEI---SSLHAPGLNLAPDPEVRE 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  83 RGLALLEEGVSITAELGGNYFggILYGAMAKYSAPITPQGRRHAVDSLKRIADFALKKGVTLGLEVvnrYESNLLNTASQ 162
Cdd:COG1082    75 AALERLKRAIDLAAELGAKVV--VVHPGSPPPPDLPPEEAWDRLAERLRELAELAEEAGVTLALEN---HEGTFVNTPEE 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 163 ALDMLDEVDAPNVVVHLDTYHMNIEESDFMQPVLACGKRLGYVHIGESN---RGYLGSGTIDFAQFFHALAMIDYKGVVT 239
Cdd:COG1082   150 ALRLLEAVDSPNVGLLLDTGHALLAGEDPVELLRKLGDRIKHVHLKDADgdqHLPPGEGDIDFAAILRALKEAGYDGWLS 229


                  ....*.
gi 1001849807 240 FESFSS 245
Cdd:COG1082   230 LEVESD 235
AP_endonuc_2 pfam01261
Xylose isomerase-like TIM barrel; This TIM alpha/beta barrel structure is found in xylose ...
 28-262 1.15e-40

Xylose isomerase-like TIM barrel; This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.


Pssm-ID: 426164 [Multi-domain]  Cd Length: 248  Bit Score: 141.35  E-value: 1.15e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  28 KAAGFDLVELSLHGPKVMDLSLT-----RDLLQEHGLEIgCSRGLTFDADVSSDDPAAVSRGLALLEEGVSITAELGGNY 102
Cdd:pfam01261   5 AELGFDGVELFTRRWFRPPLSDEeaeelKAALKEHGLEI-VVHAPYLGDNLASPDEEEREKAIDRLKRAIELAAALGAKL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 103 FGgILYGAMAKYSAPitpQGRRHAVDSLKRIADFALKKGVTLGLEVVNRYESNLLNTASQALDMLDEVDAPNVVVHLDTY 182
Cdd:pfam01261  84 VV-FHPGSDLGDDPE---EALARLAESLRELADLAEREGVRLALEPLAGKGTNVGNTFEEALEIIDEVDSPNVGVCLDTG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 183 HMNI-EESDFMQPVLAcGKRLGYVHI---------GESNRGYLGSGTIDFAQFFHALAMIDYKGVVTFESFSSTVVNEQL 252
Cdd:pfam01261 160 HLFAaGDGDLFELRLG-DRYIGHVHLkdsknplgsGPDRHVPIGEGVIDFEALFRALKEIGYDGPLSLETFNDGPPEEGA 238

                         250
                  ....*....|
gi 1001849807 253 SNALAIWRNL 262
Cdd:pfam01261 239 REGLEWLREL 248
keto_glucon_epim_IolO NF041099
5-keto-L-gluconate epimerase;
8-241 1.84e-40

5-keto-L-gluconate epimerase;


Pssm-ID: 469025  Cd Length: 269  Bit Score: 141.37  E-value: 1.84e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807   8 ALVWAGDLtpestRKVISQTKAAGFDLVELSLHGPKVMDLSLTRDLLQEHGLEIgcsrgltfdadvssddpAAVSRGLAL 87
Cdd:NF041099   16 ALAFKGDL-----EKGIEKAKKLGYDAVEIAIRDPKLVDVNELKGLLYELNLPV-----------------VAIGTGQAY 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  88 LEEGVSIT-----------------AELGGNYFGGILYGAM-AKYSAPITPQGRRHAVDSLKRIADFALKKGVTLGLEVV 149
Cdd:NF041099   74 LAEGLSLTdpdenirkkaierlkkhIDFASIFGAKVIIGLIrGKKEGRAEEEAEKLFVESMKELADYAEKKGVELVIEPL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 150 NRYESNLLNTASQALDMLDEVDAPNVVVHLDTYHMNIEESDFMQPVLACGKRLGYVHIGESNRGYLGSGTIDFAQFFHAL 229
Cdd:NF041099  154 NRYETDFINTIHEALEVIRKLNRPNVGILADTFHMNIEEPNIEESLRKCGDKLYHFHVADSNRWAPGYGHIDFDSIVKTL 233

                         250
                  ....*....|..
gi 1001849807 230 AMIDYKGVVTFE 241
Cdd:NF041099  234 KEIGYNGAVSVE 245
Hyi COG3622
Hydroxypyruvate/dehydroerythronate isomerase, Hyi/OtnI family [Carbohydrate transport and ...
 28-238 8.88e-27

Hydroxypyruvate/dehydroerythronate isomerase, Hyi/OtnI family [Carbohydrate transport and metabolism];


Pssm-ID: 442840  Cd Length: 260  Bit Score: 105.19  E-value: 8.88e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  28 KAAGFDLVELslHGPKVMDLSLTRDLLQEHGLEIGcsrGLTFDADvssdDPAAVSRGLALL-----------EEGVSITA 96
Cdd:COG3622    25 AAAGFDAVEF--LFPYDRPAEEIAAALKKHGLTLV---LFNLPAG----DWAAGERGLAALpgreaefragvDRALEYAA 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  97 ELGG---NYFGGILYGAMAKysapitPQGRRHAVDSLKRIADFALKKGVTLGLEVVNRYESN--LLNTASQALDMLDEVD 171
Cdd:COG3622    96 ALGCknlHVMAGNRPRGLDD------EAALATFVENLRYAADLAAPHGITLLIEPLNSRDHPgyFLDTTAQAVAIIEAVG 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1001849807 172 APNVVVHLDTYHMNIEESDFMQPVLACGKRLGYVHIGeSN--RGYLGSGTIDFAQFFHALAMIDYKGVV 238
Cdd:COG3622   170 SPNLKLLYDIYHMQIMEGDLIRTIRRHLPRIGHVQIA-DVpgRHEPGTGELNYPAIFKALDALGYDGWV 237
PRK13209 PRK13209
L-ribulose-5-phosphate 3-epimerase;
18-270 4.33e-13

L-ribulose-5-phosphate 3-epimerase;


Pssm-ID: 237307  Cd Length: 283  Bit Score: 68.09  E-value: 4.33e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  18 ESTRKVISQTKAAGFDLVELS----------LHGPKVMDLSLtRDLLQEHGLEIGcsrGLTFDAD----VSSDDPAAVSR 83
Cdd:PRK13209   21 ECWLEKLAIAKTAGFDFVEMSvdesderlarLDWSREQRLAL-VNALVETGFRVN---SMCLSAHrrfpLGSEDDAVRAQ 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  84 GLALLEEGVSITAELGgnyfggILYGAMAKYSA---PITPQGRRHAVDSLKRIADFALKKGVTLGLEVVNRyesNLLNTA 160
Cdd:PRK13209   97 ALEIMRKAIQLAQDLG------IRVIQLAGYDVyyeQANNETRRRFIDGLKESVELASRASVTLAFEIMDT---PFMNSI 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 161 SQALDMLDEVDAPNVVVHLDTYHMNIEESDFMQPVLACGKRLGYVHI-----GESNRGYLGSGTIDFAQFFHALAMIDYK 235
Cdd:PRK13209  168 SKALGYAHYLNSPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAFHVkdtkpGVFKNVPFGEGVVDFERCFKTLKQSGYC 247

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1001849807 236 GVVTFESFSSTVV--NEQLSNAlaiwRNLWEDSMDLA 270
Cdd:PRK13209  248 GPYLIEMWSETAEdpAAEVAKA----RDFVKARMAEA 280
PRK09997 PRK09997
hydroxypyruvate isomerase; Provisional
 119-241 1.03e-11

hydroxypyruvate isomerase; Provisional


Pssm-ID: 182188  Cd Length: 258  Bit Score: 63.82  E-value: 1.03e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 119 TPQGRRHA------VDSLKRIADFALKKGVTLGLEVVNRYE--SNLLNTASQALDMLDEVDAPNVVVHLDTYHMNIEESD 190
Cdd:PRK09997  109 TPAGFSSEqihatlVENLRYAANMLMKEDILLLIEPINHFDipGFHLTGTRQALKLIDDVGCCNLKIQYDIYHMQRMEGE 188

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1001849807 191 FMQPVLACGKRLGYVHIGES-NRGYLGSGTIDFAQFFHALAMIDYKGVVTFE 241
Cdd:PRK09997  189 LTNTMTQWADKIGHLQIADNpHRGEPGTGEINYDYLFKVIENSDYNGWVGCE 240
AP2Ec cd00019
AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester ...
 12-238 2.77e-08

AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of D-arabino-6-hexulose 3-phosphate to D-fructose 6-phosphate, via cleaving the phosphoesterbond with the sugar.


Pssm-ID: 237986  Cd Length: 279  Bit Score: 53.86  E-value: 2.77e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  12 AGDLTPESTRKVISQTKAAGFDLVELSLHGPkvmDLSLTRDLLQEH--GLEIGCSRGLTFDADV--------SSDDPAAV 81
Cdd:cd00019     4 HVSAAGFGLENALKRAKEIGFDTVAMFLGNP---RSWLSRPLKKERaeKFKAIAEEGPSICLSVhapylinlASPDKEKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  82 SRGLALLEEGVSITAELGGNYFGgILYGAMAKYSapiTPQGRRHAVDSLKRIADFALKKGVTLGLEVVNRYESNLLNTAS 161
Cdd:cd00019    81 EKSIERLKDEIERCEELGIRLLV-FHPGSYLGQS---KEEGLKRVIEALNELIDKAETKGVVIALETMAGQGNEIGSSFE 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 162 QALDMLDEVDA-PNVVVHLDTYHM-----NIEESDFMQPVLACG------KRLGYVHIGESNRGY---------LGSGTI 220
Cdd:cd00019   157 ELKEIIDLIKEkPRVGVCIDTCHIfaagyDISTVEGFEKVLEEFdkviglEYLKAIHLNDSKGELgsgkdrhepIGEGDI 236

                         250
                  ....*....|....*...
gi 1001849807 221 DFAQFFHALAMIDYKGVV 238
Cdd:cd00019   237 DGEELFKELKKDPYQNIP 254
PRK09989 PRK09989
HPr family phosphocarrier protein;
72-263 6.63e-07

HPr family phosphocarrier protein;


Pssm-ID: 182185  Cd Length: 258  Bit Score: 49.65  E-value: 6.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  72 DVSSDDPAAVSRGLALLEEGVSITAelggnyfGGILYGA-MAKYSAPITpQGRRHAVDSL----KRIADFALKKGVTLGL 146
Cdd:PRK09989   82 EARADIDLALEYALALNCEQVHVMA-------GVVPAGEdAERYRAVFI-DNLRYAADRFaphgKRILVEALSPGVKPHY 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 147 evvnryesnLLNTASQALDMLDEVDAPNVVVHLDTYHMNIEESDFMQPVLACGKRLGYVHI-GESNRGYLGSGTIDFAQF 225
Cdd:PRK09989  154 ---------LFSSQYQALAIVEEVARDNVFIQLDTFHAQKVDGNLTHLIRDYAGKYAHVQIaGLPDRHEPDDGEINYPWL 224

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1001849807 226 FHALAMIDYKGVVTFESFSSTVVNEQLSnalaiWRNLW 263
Cdd:PRK09989  225 FRLFDEVGYQGWIGCEYKPRGLTEEGLG-----WFDAW 257
PRK09856 PRK09856
fructoselysine 3-epimerase; Provisional
 97-241 1.69e-06

fructoselysine 3-epimerase; Provisional


Pssm-ID: 182116  Cd Length: 275  Bit Score: 48.29  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  97 ELGGNYFggILYGAMAKYSAPITPQGRRhAVDSLKRIADFALKKGVTLGLEVVNRYESNLLNTASQALDMLDEVDAPNVV 176
Cdd:PRK09856  101 EMNAGYT--LISAAHAGYLTPPNVIWGR-LAENLSELCEYAENIGMDLILEPLTPYESNVVCNANDVLHALALVPSPRLF 177

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 177 VHLDTYHMNIEESDFMQPVLACGKRLGYVHIGESNRG----YL-GSGTIDFAQFFHALAMIDYKGVVTFE 241
Cdd:PRK09856  178 SMVDICAPYVQAEPVMSYFDKLGDKLRHLHIVDSDGAsdthYIpGEGKMPLRELMRDIIDRGYEGYCTVE 247
PRK13210 PRK13210
L-ribulose-5-phosphate 3-epimerase;
24-241 2.41e-05

L-ribulose-5-phosphate 3-epimerase;


Pssm-ID: 237308  Cd Length: 284  Bit Score: 44.90  E-value: 2.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  24 ISQTKAAGFDLVELS----------LHGPKVMDLSLtRDLLQEHGLEIgcsRGLTFDAD----VSSDDPAAVSRGLALLE 89
Cdd:PRK13210   22 LVFAKELGFDFVEMSvdesderlarLDWSKEERLSL-VKAIYETGVRI---PSMCLSGHrrfpFGSRDPATRERALEIMK 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807  90 EGVSITAELGgnyfggILYGAMAKYSA---PITPQGRRHAVDSLKRIADFALKKGVTLGLEVVnryESNLLNTASQALDM 166
Cdd:PRK13210   98 KAIRLAQDLG------IRTIQLAGYDVyyeEKSEETRQRFIEGLAWAVEQAAAAQVMLAVEIM---DTPFMNSISKWKKW 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1001849807 167 LDEVDAPNVVVHLDT-----YHMNIEEsDFmqpvlacgkRLGYVHI-----------GESNRGY-----LGSGTIDFAQF 225
Cdd:PRK13210  169 DKEIDSPWLTVYPDVgnlsaWGNDVWS-EL---------KLGIDHIaaihlkdtyavTETSKGQfrdvpFGEGCVDFVGI 238

                         250
                  ....*....|....*.
gi 1001849807 226 FHALAMIDYKGVVTFE 241
Cdd:PRK13210  239 FKTLKELNYRGPFLIE 254
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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