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Conserved domains on  [gi|77020020|ref|YP_337799|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Lates calcarifer]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 545.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    1 MNPYVLITLLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   81 TGQWEIQQMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPADPFILITLGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  241 SLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYAMALTLSPNNATGTTPWRLSSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 77020020  321 SNLPLALSTTTSILLLPLAPAAMALFT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 545.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    1 MNPYVLITLLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   81 TGQWEIQQMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPADPFILITLGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  241 SLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYAMALTLSPNNATGTTPWRLSSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 77020020  321 SNLPLALSTTTSILLLPLAPAAMALFT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 2.12e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 89.68  E-value: 2.12e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    23 SSHWLLAWMGLEINTLAIIPLMT-QHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWEIQQ------MTHPFPT 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDElskaltGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    96 TM-----IILALALKVGLAPMHSWLPEVLQGLSLTTGLIL-STWQKLAPFAL---LLQIQPADPF---ILITLGLTSTLV 163
Cdd:pfam00361  81 LLllfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLirrSLLYLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   164 GGWGGLNQTQLRKILAYSSIAHLGWMMLIL----QFSPTITLLTLITYLLMTTSTFLVFKL-----NKATNIATLAISWT 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 77020020   235 KTPALTSLTPLILLSLGGLPPLTGFMPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 7-336 4.42e-13

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 69.98  E-value: 4.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020     7 ITLLFGLgLGTTITFTSSHWLLAWMGLEINTLAIIPLMT-QHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWE 85
Cdd:TIGR01770 106 ILLLFAL-LGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    86 IQQMTHPFPTTM------------IILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPADPF-- 151
Cdd:TIGR01770 185 FEDLLLFLSNGMlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYILFgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   152 ------ILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITL----------LTLITYLLMTTSTF 215
Cdd:TIGR01770 265 seawqiFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkavlfyifiyALMSLGAFGVLSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   216 LVFKLNKATNIATLAISWTKTPALTSLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRL 295
Cdd:TIGR01770 345 RSYKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 77020020   296 SYAMALTlSPNNATGTTPWRLSstqSNLPLALSTTTSILLL 336
Cdd:TIGR01770 425 VKVMYFD-KPERRIPSNPQSKA---QSLLLSISALFILFLG 461
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-299 4.61e-13

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 69.76  E-value: 4.61e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   4 YVLitLLFGLgLGTTITFTSSHWLLAWMGLEINTLAIIPL-MTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTG 82
Cdd:COG1007 105 YAL--LLFAT-LGMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATG 181

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  83 QWEIQQMTHPFPTT------------MIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQI----- 145
Cdd:COG1007 182 SLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveaf 261

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020 146 QPADPF---ILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQ-FSPTITLLTLITYLLMTTSTFLVF--- 218
Cdd:COG1007 262 PGLAADwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAaGTPLGVSAALFYLLAYLFMNLGAFavi 341

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020 219 -----KLNKATNIATLAISWTKTPALT--------SLT--PlillslgglpPLTGFMPKWLILQELTKQDLSTLATLTAL 283
Cdd:COG1007 342 lllsrKGGEAEEIEDLAGLARRSPLLAlamtifllSLAgiP----------PTAGFFGKFYVFSAAVEAGLYWLAVIAVL 411

                       330
                ....*....|....*.
gi 77020020 284 TALLSLFFYLRLSYAM 299
Cdd:COG1007 412 NSVISAYYYLRVVKAM 427
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 545.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    1 MNPYVLITLLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   81 TGQWEIQQMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPADPFILITLGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  241 SLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYAMALTLSPNNATGTTPWRLSSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 77020020  321 SNLPLALSTTTSILLLPLAPAAMALFT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 3.44e-137

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 393.52  E-value: 3.44e-137
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    1 MNPYVLITLLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWL 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   81 TGQWEIQQMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPA-DPFILITLGLT 159
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLlNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPAL 239
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  240 TSLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYAMALTLSPNNATGTTPWRLsST 319
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                        330       340
                 ....*....|....*....|....*..
gi 77020020  320 QSNLPLALSTTTSILLLPLAPAAMALF 346
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 6.75e-118

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 344.50  E-value: 6.75e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    1 MNPYVLITLLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWL 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   81 TGQWEIQQMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPA-DPFILITLGLT 159
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSlNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPAL 239
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  240 TSLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYAMALTLSPNNATGTTPWRLSST 319
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*..
gi 77020020  320 QSNLpLALSTTTSILLLPLAPAAMALF 346
Cdd:MTH00112 321 KNTL-TATLTTLSTLLLPLSPMILTII 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-346 1.27e-116

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 341.44  E-value: 1.27e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    1 MNPYVLITLLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWL 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   81 TGQWEIQQMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPA-DPFILITLGLT 159
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSiNPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPAL 239
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  240 TSLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYAMALTLSPNNATGTTPWRLSST 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 77020020  320 QSNLPLALSTTTSILLLPLAPAAMALF 346
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-347 2.56e-105

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 312.67  E-value: 2.56e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    1 MNPYVLITLLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWL 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   81 TGQWEIQQMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPA-DPFILITLGLT 159
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPAlNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPAL 239
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  240 TSLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYAMALTLSPNNATGTTPWRLSST 319
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*...
gi 77020020  320 qSNLPLALSTTTSILLLPLAPAAMALFT 347
Cdd:MTH00200 321 -SNLLVGLLLLLSILGLPLTPQLLFLFF 347
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-340 7.47e-83

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 255.24  E-value: 7.47e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    1 MNPYVLITLLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWL 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   81 TGQWEIQQMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQI-QPADPFILITLGLT 159
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISIsNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPAL 239
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  240 TSLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYAMALTLSPNNATGTTPWRLSST 319
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                        330       340
                 ....*....|....*....|.
gi 77020020  320 QSNLPLALSTTTSILLLPLAP 340
Cdd:MTH00041 321 ITVYGVILSILSSISILGLLL 341
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 9.37e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 174.63  E-value: 9.37e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    1 MNPYVLITLLFgLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWL 80
Cdd:MTH00160   3 MNSSKLLFLST-LIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   81 TGqweiqqMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPadPFILITLGLTS 160
Cdd:MTH00160  82 LM------LFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN--NNFIIIIIILS 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPALT 240
Cdd:MTH00160 154 AIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIK 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  241 SLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYAMALTLSPNNatgttPWRLSSTQ 320
Cdd:MTH00160 234 FLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKN-----KWNLKKKK 308

                        330
                 ....*....|....*...
gi 77020020  321 SNLPLALSTTTSILLLPL 338
Cdd:MTH00160 309 NKFSLILNFLSFISLFGL 326
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 10-318 5.89e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 159.28  E-value: 5.89e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   10 LFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWEIqqm 89
Cdd:MTH00144  10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS--- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   90 thpfpTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPADP--FILITLGLTSTLVGGWG 167
Cdd:MTH00144  87 -----MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWlaYLLCVISVLSALVGSIG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  168 GLNQTQLRKILAYSSIAHLGWMMLILQFSPtiTLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPALTSLTPLIL 247
Cdd:MTH00144 162 GLNQTQVRALLAYSSISHTGWMLVAILHGS--WLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISL 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77020020  248 LSLGG-LPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYAMALTLSPNNATGTTPWRLSS 318
Cdd:MTH00144 240 LLSLGgLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSS 311
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 15-298 4.00e-40

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 144.15  E-value: 4.00e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   15 LGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTnawltgQWEIQQMTHPFP 94
Cdd:MTH00011  17 LGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM------MWSFPSLLKNIT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   95 TTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPADPFILIT-LGLTSTLVGGWGGLNQTQ 173
Cdd:MTH00011  91 ALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTsMAAMSALAGGLGGMNQTQ 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  174 LRKILAYSSIAHLGWMMLILQFSPTITLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPALTSLTPLILLSLGGL 253
Cdd:MTH00011 171 LRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGL 250

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 77020020  254 PPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYA 298
Cdd:MTH00011 251 PPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN 295
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-338 5.64e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 130.18  E-value: 5.64e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    9 LLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLF---ASTTNAWLTgqwe 85
Cdd:MTH00197   3 FLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMggsLSFSNLYLS---- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   86 iqqmthPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQpADPFILITLGLTSTLVGG 165
Cdd:MTH00197  79 ------LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNS-SSFMGLLICSVLSSLIGG 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  166 WGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITLLTLITYLLMTTSTFLVFKLNKATNIATLAISWTKTPALTSLTPL 245
Cdd:MTH00197 152 IGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  246 ILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRLSYAmalTLSPNNATGTTPWRLSSTQSNLPL 325
Cdd:MTH00197 232 SFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYK---SLILSNWMINFLMKINLLYSGLFI 308

                        330
                 ....*....|...
gi 77020020  326 ALSTTTSILLLPL 338
Cdd:MTH00197 309 LLMMMLPLLMIFT 321
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 15-191 1.09e-21

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 94.33  E-value: 1.09e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   15 LGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHP-RAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWEIQ------ 87
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLSyinlvl 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   88 -------QMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPADPFILItLGLTS 160
Cdd:MTH00196  84 nsgqsfsSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLI-GGLFS 162

                        170       180       190
                 ....*....|....*....|....*....|.
gi 77020020  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMML 191
Cdd:MTH00196 163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLW 193
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 2.12e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 89.68  E-value: 2.12e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    23 SSHWLLAWMGLEINTLAIIPLMT-QHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWEIQQ------MTHPFPT 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDElskaltGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    96 TM-----IILALALKVGLAPMHSWLPEVLQGLSLTTGLIL-STWQKLAPFAL---LLQIQPADPF---ILITLGLTSTLV 163
Cdd:pfam00361  81 LLllfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLirrSLLYLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   164 GGWGGLNQTQLRKILAYSSIAHLGWMMLIL----QFSPTITLLTLITYLLMTTSTFLVFKL-----NKATNIATLAISWT 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 77020020   235 KTPALTSLTPLILLSLGGLPPLTGFMPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-191 7.74e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 90.08  E-value: 7.74e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   13 LGLGTTITFTSSHWLLAWMGLEINTLAI-IPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWEIQQ--- 88
Cdd:MTH00199 106 VALGSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGins 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   89 -MTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPADPFILITLGLtSTLVGGWG 167
Cdd:MTH00199 186 iLTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVL-SIIYGAIG 264

                        170       180
                 ....*....|....*....|....
gi 77020020  168 GLNQTQLRKILAYSSIAHLGWMML 191
Cdd:MTH00199 265 ALNQTKIKRLLAYSGIGHMGFILF 288
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 7-336 4.42e-13

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 69.98  E-value: 4.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020     7 ITLLFGLgLGTTITFTSSHWLLAWMGLEINTLAIIPLMT-QHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWE 85
Cdd:TIGR01770 106 ILLLFAL-LGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    86 IQQMTHPFPTTM------------IILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPADPF-- 151
Cdd:TIGR01770 185 FEDLLLFLSNGMlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYILFgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   152 ------ILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQFSPTITL----------LTLITYLLMTTSTF 215
Cdd:TIGR01770 265 seawqiFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkavlfyifiyALMSLGAFGVLSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   216 LVFKLNKATNIATLAISWTKTPALTSLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFYLRL 295
Cdd:TIGR01770 345 RSYKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 77020020   296 SYAMALTlSPNNATGTTPWRLSstqSNLPLALSTTTSILLL 336
Cdd:TIGR01770 425 VKVMYFD-KPERRIPSNPQSKA---QSLLLSISALFILFLG 461
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-299 4.61e-13

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 69.76  E-value: 4.61e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   4 YVLitLLFGLgLGTTITFTSSHWLLAWMGLEINTLAIIPL-MTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTG 82
Cdd:COG1007 105 YAL--LLFAT-LGMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATG 181

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  83 QWEIQQMTHPFPTT------------MIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQI----- 145
Cdd:COG1007 182 SLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveaf 261

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020 146 QPADPF---ILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILQ-FSPTITLLTLITYLLMTTSTFLVF--- 218
Cdd:COG1007 262 PGLAADwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAaGTPLGVSAALFYLLAYLFMNLGAFavi 341

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020 219 -----KLNKATNIATLAISWTKTPALT--------SLT--PlillslgglpPLTGFMPKWLILQELTKQDLSTLATLTAL 283
Cdd:COG1007 342 lllsrKGGEAEEIEDLAGLARRSPLLAlamtifllSLAgiP----------PTAGFFGKFYVFSAAVEAGLYWLAVIAVL 411

                       330
                ....*....|....*.
gi 77020020 284 TALLSLFFYLRLSYAM 299
Cdd:COG1007 412 NSVISAYYYLRVVKAM 427
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 9-191 4.87e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 66.81  E-value: 4.87e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    9 LLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAV---------EATTKYFLTQATAAAMLLFASTTNAW 79
Cdd:MTH00198 193 LVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFG 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   80 LTGQ--------------WEIQQMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQI 145
Cdd:MTH00198 273 FTGNegmlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL 352

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 77020020  146 QPADPfILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMML 191
Cdd:MTH00198 353 VITSK-LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILI 397
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-340 3.74e-11

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 57.65  E-value: 3.74e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 77020020   290 FFYLRLSYAMALTLSPNNATGTTPWRLSSTQSNLPLALSTTTSILLLPLAP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
4-299 4.92e-11

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 63.69  E-value: 4.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    4 YVLItlLFGLgLGTTITFTSSHWLLAWMGLEINTLAIIPL-MTQHHHPRAVEATTKYFLTQATAAAMLLF--------AS 74
Cdd:PRK05777 106 YLLV--LFAL-LGMMVMVSANDLLTLFLGLELLSLPLYALaALRRDRRRSLEAAIKYFVLGALASGFLLYgmsllygaTG 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   75 TTN----AWLTGQWEIQQMTHPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQI----- 145
Cdd:PRK05777 183 SLSfagiAKALADGSGNSLLLLFGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLlvvaf 262

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  146 QPADPF---ILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMML-ILQFSPTITLLTLITYLLMTTSTFLVF--- 218
Cdd:PRK05777 263 GGLSEDwqqVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVgLAAGTAEGYSAVLFYLLAYLFMTLGAFgvi 342

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  219 -----KLNKATNIATLA-ISWTKtPALTSLTPLILLSLGGLPPLTGFMPKWLILQELTKQDLSTLATLTALTALLSLFFY 292
Cdd:PRK05777 343 sllrrKGGEAESISDFAgLSKRS-PLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYY 421


                 ....*..
gi 77020020  293 LRLSYAM 299
Cdd:PRK05777 422 LRVIKLM 428
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 8-267 6.47e-10

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 60.16  E-value: 6.47e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   8 TLLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWEIQ 87
Cdd:COG0651 111 PLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMA 190

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  88 QMTHPFPT----------TMIILALALKVGLAPMHSWLPE-----------VLQGLSLTTGL--ILSTWQKLAPFALLLQ 144
Cdd:COG0651 191 DLAARLAEldpglllaafALLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALF 270

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020 145 IQPadpfILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMMLILqfsptitlltlITYLLMTTSTFLVFKLNKAT 224
Cdd:COG0651 271 LGT----LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGL-----------GLGTPLGLAGALFHLLNHAL 335

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77020020 225 NIATL------AISWTKTPALTSLTPLILLSLGGLPPLT-------------GFMPKWLILQ 267
Cdd:COG0651 336 AKALLflaagaIERATGTRDLDKLGGLGKRMPLTAAAFLigalalaglpplsGFVSKWLLLQ 397
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-191 6.85e-08

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 53.93  E-value: 6.85e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  49 HPRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQW--EIQQ-MTHPFPTTM-------IILALALKVGLAPMHSWLPEV 118
Cdd:COG1008 156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAElAAAPLPLTAqlllflaFFIAFAVKVPMFPFHTWLPDA 235

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020 119 LQGLSLTTGLILS-TWQKLAPFALL---LQIQP--ADPF--ILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMM 190
Cdd:COG1008 236 HVEAPTAGSVLLAgVLLKMGGYGLLrfaLPLFPeaSAYFapLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVL 315


                .
gi 77020020 191 L 191
Cdd:COG1008 316 L 316
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-191 1.61e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 52.79  E-value: 1.61e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   33 LEINTLAIIPLMTQHHH-PRAVEATTKYFLTQATAAAMLLFASttnAWLTGQWEIQQMTH--------PFPTTMIILA-- 101
Cdd:PRK08376 150 LEIMSIASYALVAFRNDtWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYlavkmsenPTVVAKIALAlf 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  102 ---LALKVGLAPMHSWLPEVLQGL--SLTTGLILSTWQKLAPFALLL------QIQPAD-PFILITLGLTSTLVGGWGGL 169
Cdd:PRK08376 227 iagLAMKSGAVPVHMWLPDAYPAApsSISAMLLVIKQAGLYALARVLfsiygpAINLATvGWVIIILGCLTMFVGVAMAV 306

                        170       180
                 ....*....|....*....|..
gi 77020020  170 NQTQLRKILAYSSIAHLGWMML 191
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYMLL 328
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 20-191 2.14e-07

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 52.24  E-value: 2.14e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   20 TFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFL------TQATAAAMLLFAS----TTNAWLTGQW-EIQQ 88
Cdd:PRK06458 124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANaatvMGDGEMAILWtELLK 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   89 MTHPFPTTMIILALAL-------KVGLAPMHSWLPE-----------VLQGLSLTTGLILstwqkLAPFALLLQIQPADP 150
Cdd:PRK06458 204 HASLLDPTLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYA-----VLRYYILIDAAIGSD 278

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 77020020  151 F---ILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMML 191
Cdd:PRK06458 279 FpgrLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-191 2.43e-07

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 52.25  E-value: 2.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    50 PRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQ-WEIQQ-MTHPFPTTM-------IILALALKVGLAPMHSWLPEV-L 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLElLNLPLPFGVqtwlflaFFIAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 77020020   120 QGLSLTTGLILSTWQKLAPFALLLQIQPADP-------FILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMML 191
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTYGFLRFNLPLFPdaslyfaPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLL 310
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-191 2.99e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 51.80  E-value: 2.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   33 LEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWEIQQMTHPFP--------TTMIILALAL 104
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGALAenptvvtaFGFVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  105 KVGLAPMHSWLPEVLQGLSLTTGLILS-TWQKLAPFALL----------LQIQPADPFILITLGLTSTLVGGWGGLNQTQ 173
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAAPPVVTALLSgLVTKVAVYALIriyftvfggdFRFALGLGWLLAVLALLSMLVGSLAALGQDD 294

                        170
                 ....*....|....*...
gi 77020020  174 LRKILAYSSIAHLGWMML 191
Cdd:PRK08375 295 VKRVLAYSTVSQMGYILL 312
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-191 5.38e-07

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 50.97  E-value: 5.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   50 PRAVEATTKYFL-TQATAAAML---LFASTTNAWLTGQWEIQQ-MTHPFPTTM-------IILALALKVGLAPMHSWLPE 117
Cdd:PRK05846 157 KNRIYAATKFFLyTLLGSLLMLvaiIYLVVVYYNATGTFDIADlLNLPLPPGVqywlflaFFIAFAVKMPMFPLHTWLPD 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  118 VLQ-----GLSLTTGLILstwqKLAPFALL---LQIQPADP----FILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAH 185
Cdd:PRK05846 237 AHVqaptaGSVLLAGILL----KMGAYGLLrfsLPLFPDAShefaPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISH 312


                 ....*.
gi 77020020  186 LGWMML 191
Cdd:PRK05846 313 MGFVTL 318
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 48-191 1.43e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 49.97  E-value: 1.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   48 HHPRAVEATTKYFLTQATAAAMLLFA--------STTN-----AWLTGQWEIQQMT---HPFPTTMIILALAL-----KV 106
Cdd:PRK12667 158 DRGDAVEAAIKYALIGAVGTTLYFLAlaflyatfGTLNmadlsAKIRGLSFPLTGGlagNPPLALGVALALALwaftiKA 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  107 GLAPMHSWLPEV-----------LQGLSLTTG---------LILSTWQKLAPFALLLQiqpadpFILITLGLTSTLVGGW 166
Cdd:PRK12667 238 AIFPNHFWLPDAhpaapspvsamLSGLVVNVGayaiirflyTIFGISPSLIDFRAALS------PILIILGAVSAIIGAL 311

                        170       180
                 ....*....|....*....|....*
gi 77020020  167 GGLNQTQLRKILAYSSIAHLGWMML 191
Cdd:PRK12667 312 MMVVQKDVKRLLAYSTISHMGYIFM 336
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-191 3.03e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 45.52  E-value: 3.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   17 TTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATA------AAMLLFASTTNAWLTG--QW-EIQ 87
Cdd:PRK08676 115 ITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGtlNWtELA 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   88 QMTHPFPTTMIILA-------LALKVGLAPMHSWLPE-----------VLQGLSLTTGLilstWQKLAPFALLLQIQPAD 149
Cdd:PRK08676 195 AHASLLSPSVLGASflfifigFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGI----YGILRLSALLRQSGAAE 270

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 77020020  150 PF--ILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMML 191
Cdd:PRK08676 271 QFsnVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLL 314
PRK12668 PRK12668
Na(+)/H(+) antiporter subunit D;
50-190 3.22e-05

Na(+)/H(+) antiporter subunit D;


Pssm-ID: 237168 [Multi-domain]  Cd Length: 581  Bit Score: 45.66  E-value: 3.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   50 PRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWEIQQM--THPFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTG 127
Cdd:PRK12668 139 KAAVRAGFRYLLVHVLGGVLLLAGILLHYAETGSFAFGAIagLGGTAAWLILIGFGVNAAFPPLHAWLPDAYPEATVTGS 218

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 77020020  128 LILSTW-QKLAPFALLLQIQPADpfILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMM 190
Cdd:PRK12668 219 VFLSAFtTKTAVYALARAFPGTE--LLIYIGAAMAVYGVFFALLENDLRRLLSYHIVSQVGYMV 280
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
9-191 3.84e-05

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 45.46  E-value: 3.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020    9 LLFGLGLGTTITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWEI-- 86
Cdd:PRK06473 112 LLLLLNAGVSGAFLAQDLLLFFLFYELELIPLYLLIAIWGGQRRGYAATKFLLYTAISGILILVSFLGLVWLSGASSFdy 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   87 -QQMTHPFPTTM-------IILALALKVGLAPMHSWLPE-----------VLQGLSLTTG----------LILSTWQKLA 137
Cdd:PRK06473 192 ePLRSHTLPLSTqllllapILVGFGIKIPLVPFHTWLPDahveastpvsvLLAGVLLKLGtygllrfgvgLFPEAWVYLA 271

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 77020020  138 PFalllqiqpadpfiLITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMML 191
Cdd:PRK06473 272 PW-------------LATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILL 312
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
55-191 1.52e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 43.55  E-value: 1.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   55 ATTKYFLTQATAAAMLLFASTTNAWLTGQWEI---QQMTHPFPT-------TMIILALALKVGLAPMHSWLPEVLQGLSL 124
Cdd:PRK07363 158 ASIKFLIYTAVSGLLVLAAFLGIVWLSGSTSFdydAISTQNLSLntqlillTGLLLGFGIKIPLVPLHTWLPDAYTEASP 237

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 77020020  125 TTGLILS-TWQKLAPFALL---LQIQPADPFI----LITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMML 191
Cdd:PRK07363 238 AVAILLGgVLAKLGTYGLLrfgLQLFPQTWSLvapgLAIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYILV 312
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 152-193 1.98e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 43.22  E-value: 1.98e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|..
gi 77020020 152 ILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMMLIL 193
Cdd:COG1009 277 VVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 98-193 3.35e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 42.22  E-value: 3.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   98 IILALALKVGLAPMHSWLPEV-----LQGLSLTTGLILstwqKLAPFALLLQIQPADPF-------ILITLGLTSTLVGG 165
Cdd:MTH00226 236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILL----KLGGYGLVRLSWPILPLgaqnlapAVIAMGIVGIVYGS 311

                         90       100
                 ....*....|....*....|....*...
gi 77020020  166 WGGLNQTQLRKILAYSSIAHLGWMMLIL 193
Cdd:MTH00226 312 FATCRQIDVKRLVAYSSVAHMGLVSITL 339
ND5 MTH00066
NADH dehydrogenase subunit 5; Provisional
 78-190 4.65e-04

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214416 [Multi-domain]  Cd Length: 598  Bit Score: 41.82  E-value: 4.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   78 AWL---TGQWEIQQMTHPFPTTMI-----ILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQP-- 147
Cdd:MTH00066 185 AWLamnTNSWELQQIFLLNDNSTLpllglILAAAGKSAQFGLHPWLPAAMEGPTPVSALLHSSTMVVAGIFLLIRFHPll 264

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 77020020  148 -ADPFILIT---LGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMM 190
Cdd:MTH00066 265 eNNQTALTIclcLGALTTLFTAACALTQNDIKKIVAFSTSSQLGLMM 311
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-262 5.97e-04

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 41.53  E-value: 5.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   51 RAVEATTKYFLTQATAAAMLLFASTtnaWLTGQ-------WEI------QQMTHPFPT----TMIILALALKVGLAPMHS 113
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGFS---WLYGLsggeielQEIvnglinTQMYNSPGIsialIFITVGIGFKLSLAPFHQ 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  114 WLPEVLQGLSLTTGLILSTWQKLAPFALLLQI--------QPADPFILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAH 185
Cdd:CHL00049 236 WTPDVYEGSPTPVVAFLSVTSKVAASALATRIfdipfyfsSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQ 315

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  186 LGWMML-ILQFSP----TITLLTLITYLLMTTSTF---LVFKLNKAT-NIATLAISWTKTPALTSLTPLILLSLGGLPPL 256
Cdd:CHL00049 316 IGYVIIgIIVGDSndgyASMITYMLFYIFMNLGTFaciVLFGLRTGTdNIRDYAGLYTKDPFLALSLALCLLSLGGIPPL 395


                 ....*.
gi 77020020  257 TGFMPK 262
Cdd:CHL00049 396 AGFFGK 401
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 19-191 1.06e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 40.71  E-value: 1.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   19 ITFTSSHWLLAWMGLEINTLAIIPLMTQHHHPRAVEATTKYFLTQATA------AAMLLFASTTNAWLTGQweiqQMTHP 92
Cdd:PRK07234 109 AAFVCADLISLYVALEVLSIATFLLVAYPRTDRAIWVGLRYLFYSNVAmlfyliGAVLVYQANGTFAFSGL----ATADP 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   93 FPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILS-TWQKLAPFALL---LQIQPADPfILITLGLTSTLVGGWGG 168
Cdd:PRK07234 185 EAFALIALGLLVKGGIFVSGLWLPLTHSEAEPPVSALLSgVVVKAGVFPLVrcaLDVPGLDL-IVRIFGVGTALLGVLFA 263

                        170       180
                 ....*....|....*....|...
gi 77020020  169 LNQTQLRKILAYSSIAHLGWMML 191
Cdd:PRK07234 264 LLEKDLKRMLAFSTISQLGFILA 286
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 48-196 1.34e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 40.58  E-value: 1.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   48 HHPRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQWEIQQM-----------THPFPTTMIILAL---ALKVGLAPMHS 113
Cdd:PRK12649 156 HRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATIlqdselienikGHPLFLITLILIFigaAAKSAQGPFYI 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  114 WLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQP-----ADPFILIT-LGLTSTLVGGWGGLNQTQLRKILAYSSIAHLG 187
Cdd:PRK12649 236 WLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPifsgtEAWFILVSgTGMITMVLAGFLAFRQTDIKAILAYSTISQLA 315


                 ....*....
gi 77020020  188 WMMLILQFS 196
Cdd:PRK12649 316 YLMTMYGYT 324
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 99-193 1.60e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 40.29  E-value: 1.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   99 ILALAL-KVGLAPMHSWLPE-----------------VLQGLSLTTglilstwqKLAP-FALLLQIQPadpfILITLGLT 159
Cdd:PRK12644 209 ILVGALsKSAIVPFHFWLPGamaaptpvsaylhaaamVKAGIYLVA--------RLAPgFADVPVWRP----TVLVLGLA 276

                         90       100       110
                 ....*....|....*....|....*....|....
gi 77020020  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMMLIL 193
Cdd:PRK12644 277 TMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
110-191 1.89e-03

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 40.01  E-value: 1.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  110 PMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPAD---PFILITLGLTSTL---VGGWGGLNQTQLRKILAYSSI 183
Cdd:PRK07376 245 PLHVWLPDAMEGPTPISALIHAATMVAAGVFLVARMYPVFeqfPAVMTVIAWTGAItafLGASIALTQNDIKKGLAYSTI 324


                 ....*...
gi 77020020  184 AHLGWMML 191
Cdd:PRK07376 325 SQLGYMVM 332
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-191 3.40e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 39.26  E-value: 3.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  100 LALALKVGLAPMHSWLPE-----------VLQGLSLTTG---LILSTWqKLAPFAlllqIQPADPFILiTLGLTSTLVGG 165
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQahveapvagsvILAGVLLKLGgygFIRFSW-PLLPEA----SEYFSPLIQ-TLSLLAIIYGS 287

                         90       100
                 ....*....|....*....|....*.
gi 77020020  166 WGGLNQTQLRKILAYSSIAHLGWMML 191
Cdd:MTH00217 288 LTTCRQVDLKRIIAYSSVAHMGLVTL 313
PRK12646 PRK12646
DUF4040 family protein;
92-190 3.81e-03

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 39.35  E-value: 3.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   92 PFPTTMIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQP----ADPFILI--TLGLTSTLVGG 165
Cdd:PRK12646 210 IPMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLFRFTPllglSNMYIYIvtFVGLITMLFGS 289

                         90       100
                 ....*....|....*....|....*
gi 77020020  166 WGGLNQTQLRKILAYSSIAHLGWMM 190
Cdd:PRK12646 290 ITALKQWDLKGILAYSTISQLGMIM 314
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 111-196 4.65e-03

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 38.90  E-value: 4.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  111 MHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQP---ADPFILITLGLTSTL---VGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00020 229 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLLIRSSPlfeQAPLALIIVTIVGSLtvfFAATVGLVQNDLKKVIAYSTCS 308

                         90
                 ....*....|..
gi 77020020  185 HLGWMMLILQFS 196
Cdd:MTH00020 309 QLGYMVVACGLS 320
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-191 5.49e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 38.47  E-value: 5.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   55 ATTKYFLTQATAAAMLLFASTTNAWLTGQ--WEIQQMTH-PFPTTMIILALA-------LKVGLAPMHSWLPEVLQGLSL 124
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAkSYPLALELLLYAgfliafgVKLPIFPLHTWLPDAHGEASA 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 77020020  125 TTGLILS-TWQKLAPFALL---LQIQPADPF----ILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMML 191
Cdd:PRK12561 218 PVSMILAgVLLKMGGYALIrfnVQMLPDAHVyfapALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLL 292
PRK12650 PRK12650
DUF4040 family protein;
110-189 8.23e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 38.10  E-value: 8.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  110 PMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPA---DP---FILITLGLTSTLVGGWGGLNQTQLRKILAYSSI 183
Cdd:PRK12650 226 PFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVfhdVAvwnWLLIIVGMITALMGAVFAVQKTDLKKLTAYSTV 305


                 ....*.
gi 77020020  184 AHLGWM 189
Cdd:PRK12650 306 SQLGWI 311
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-262 8.90e-03

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 37.72  E-value: 8.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   50 PRAVEATTKYFLTQATAAAMLLFASTTNAWLTGQW----EIQQMTHPFPTTMIILAL-------ALKVGLAPMHSWLPEV 118
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYGSSLLYGLSGGStqlsAIALALITSPSLGLALALvfviagiAFKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  119 LQGLSLTTGLILSTWQKLAPFALLLQI-QPADP-------FILITLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMM 190
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAGFALAIRLlVTAFPsfdeqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020  191 LILQF-------SPTITLLTLITYLLMTTSTFLVFKLNKATN-IATLAISWTKTPALTSLTPLILLSLGGLPPLTGFMPK 262
Cdd:PRK02504 317 IGLVAgteagyaSMVFYLLAYLFMNLGAFACVILFSLRTGTDqISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 97-196 9.98e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 37.16  E-value: 9.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77020020   97 MIILALALKVGLAPMHSWLPEVLQGLSLTTGLILSTWQKLAPFALLLQIQPADPFILITLGLTSTLVGGWgglNQTQLRK 176
Cdd:MTH00091  62 FQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQMF---LLKSYKN 138

                         90       100
                 ....*....|....*....|
gi 77020020  177 ILAYSSIAHLGWMMLILQFS 196
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFS 158
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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