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Conserved domains on  [gi|66276042|ref|YP_238253|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Chlorocebus aethiops]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-173 2.33e-77

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 228.15  E-value: 2.33e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042    1 MTYILFALSVLLVMGFVGFSSKPSPIYGGLALIVSGVVGCMVILGFGGAYMGLMLFLIYLGGMMIVFGYTTAMAIEEYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042   81 TWGSGFEVLGGLLVGLMMEAGLVLWVSSSD-GVVVVSFNSMGSWVIFEGEGPGLVRGDSIGAGALYDYGRWLVVVAGWTL 159
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDeVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|....
gi 66276042  160 FVGVYIVIEITRGN 173
Cdd:MTH00109 162 FIGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-173 2.33e-77

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 228.15  E-value: 2.33e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042    1 MTYILFALSVLLVMGFVGFSSKPSPIYGGLALIVSGVVGCMVILGFGGAYMGLMLFLIYLGGMMIVFGYTTAMAIEEYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042   81 TWGSGFEVLGGLLVGLMMEAGLVLWVSSSD-GVVVVSFNSMGSWVIFEGEGPGLVRGDSIGAGALYDYGRWLVVVAGWTL 159
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDeVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|....
gi 66276042  160 FVGVYIVIEITRGN 173
Cdd:MTH00109 162 FIGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-169 4.29e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.12  E-value: 4.29e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042    17 VGFSSKPSPIYGGLALIVSGVVGCMVILGFGGAYMGLMLFLIYLGGMMIVFGYTTAMAIEEYPETWGSGFEVLGGLLVGL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 66276042    97 MMEAGLVLWVSSSDGVVVvsfnsmgswviFEGEGPGLVRGDSIGAGALYDYGrWLVVVAGWTLFVGVYIVIEI 169
Cdd:pfam00499  81 LLLALLLLVLLSASLTPA-----------AAAAAPDVGNIEAIGELLFTDYL-LPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-173 2.33e-77

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 228.15  E-value: 2.33e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042    1 MTYILFALSVLLVMGFVGFSSKPSPIYGGLALIVSGVVGCMVILGFGGAYMGLMLFLIYLGGMMIVFGYTTAMAIEEYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042   81 TWGSGFEVLGGLLVGLMMEAGLVLWVSSSD-GVVVVSFNSMGSWVIFEGEGPGLVRGDSIGAGALYDYGRWLVVVAGWTL 159
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDeVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|....
gi 66276042  160 FVGVYIVIEITRGN 173
Cdd:MTH00109 162 FIGVFVIIEITRGN 175
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 2.89e-32

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 113.31  E-value: 2.89e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042    1 MTYILFALSVLLVMGFVGFSSKPSPIYGGLALIVSGVVGCMVILGFGGAYMGLMLFLIYLGGMMIVFGYTTAMAIEEYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042   81 TWGSG--FEVLGGLLVGLMMEAGLVLWVSSSdgvvvvsfnsmGSWVIF-EGEGPGLVRGDSIGAGALYDYGRWLVVVAGW 157
Cdd:MTH00138  81 SWGSWsvLGYVVGYLVGVVLAAGLFWGGWYE-----------GSWVVVdELKEFSVLRGDVGGVALMYSSGGGMLVICAW 149

                        170
                 ....*....|....*
gi 66276042  158 TLFVGVYIVIEITRG 172
Cdd:MTH00138 150 VLLLTLFVVLELTRG 164
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 1.82e-27

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 101.08  E-value: 1.82e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042    1 MTYILFALSVLLVMGFVGFSSKPSPIYGGLALIVSGVVGCMVILGFGGAYMGLMLFLIYLGGMMIVFGYTTAMAIEEYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042   81 TWGSGFEVLGGLLVGLMMEAGLVLWVSSSdgvvvvsfnSMGSWVIFEGEGPGLVRGDSIGAGALYDYGRWLVVVAGWTLF 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNF---------SLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLL 151

                        170
                 ....*....|..
gi 66276042  161 VGVYIVIEITRG 172
Cdd:MTH00065 152 LTLFVVLEVTRG 163
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.77e-23

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 90.96  E-value: 1.77e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042    1 MTYILFALSVLLVMGFVGFSSKPSPIYGGLALIVSGVVGCMVILGFGGAYMGLMLFLIYLGGMMIVFGYTTAMAIEEYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042   81 TWGSGFEVLGGLLVGLMMeagLVLWVSSSDGVVVVSFNSmgswVIFEGEGPGLVRGDSIGAGALYDYGRWLVVVAGWTLF 160
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVV---VVVGVVVGGLWGMEGVGV----VTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLL 153

                        170
                 ....*....|..
gi 66276042  161 VGVYIVIEITRG 172
Cdd:MTH00115 154 LTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 4.87e-13

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 63.47  E-value: 4.87e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042    1 MTYILFALSVLLVMGFVGFSSKPSPIYGGLALIVSGVVGCMVILGFGGAYMGLMLFLIYLGGMMIVFGYTTAMAIEEYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042   81 TWGSGfevlggllvGLMMEAGLVLWVSSSDGVVVVSFNSMGSWVIFEGEGpglvRGDSIGAGALYDYGRWLVVVAGWTLF 160
Cdd:MTH00214  81 SWGGW---------SVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEAN----NLDLSGVSDLYSRGFFLLLLGGVVLF 147

                        170
                 ....*....|..
gi 66276042  161 VGVYIVIEITRG 172
Cdd:MTH00214 148 LVLFVVLELVRG 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-173 6.58e-12

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 60.30  E-value: 6.58e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042    1 MTYILFALSVLLVMGFVGFSSkpSPIYGGLALIVSGVVGCMVILGFGGAYMGLMLFLIYLGGMMIVFGYTTAMAIEEYPE 80
Cdd:MTH00045   1 MVFYLFLILMLFGSTLVFYSL--SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042   81 TWGSGfEVLGGLLVglmmeagLVLWVSSSDGVVVVSFNSMGSWVIFEGEgpglvrgdsIGAGALYDYGRWLVVVAGWTLF 160
Cdd:MTH00045  79 VSNLG-EVLVLSLL-------LSLWVFISFDNFLELSNNNWSLVSLSDL---------VGSSELYNSGGLYLLLGGFILL 141

                        170
                 ....*....|...
gi 66276042  161 VGVYIVIEITRGN 173
Cdd:MTH00045 142 VALVVALVISFGH 154
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-169 4.29e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.12  E-value: 4.29e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276042    17 VGFSSKPSPIYGGLALIVSGVVGCMVILGFGGAYMGLMLFLIYLGGMMIVFGYTTAMAIEEYPETWGSGFEVLGGLLVGL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 66276042    97 MMEAGLVLWVSSSDGVVVvsfnsmgswviFEGEGPGLVRGDSIGAGALYDYGrWLVVVAGWTLFVGVYIVIEI 169
Cdd:pfam00499  81 LLLALLLLVLLSASLTPA-----------AAAAAPDVGNIEAIGELLFTDYL-LPFELASVLLLVALVGAIVL 141
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 8-74 1.81e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 36.91  E-value: 1.81e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 66276042    8 LSVLLVMGFVgFSSKPSPIYGGLALIVSGVVGCMVILGFGGAYMGLMLFLIYLGGMMIVFGYTTAMA 74
Cdd:MTH00212   7 LSLLLLLMLL-FPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALS 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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