NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2749600198|ref|XP_502292|]
View 

Cell pattern formation-associated protein StuA [Yarrowia lipolytica]

Protein Classification

KilA-N domain-containing protein( domain architecture ID 10516234)

KilA-N domain-containing protein is a DNA-binding protein such as Saccharomyces cerevisiae transcription factor PHD1 that functions in pseudohyphal growth

CATH:  3.10.260.10
Gene Ontology:  GO:0003700|GO:0043565
PubMed:  11897024
SCOP:  4001103

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
KilA-N pfam04383
KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved ...
 287-361 1.47e-09

KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.


:

Pssm-ID: 367917  Cd Length: 107  Bit Score: 55.41  E-value: 1.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749600198 287 RREDNDMINGTKLLNVAGMTRGRRDGILKGEKLRHVVKAGAMH------------------LKGVWIPYDRALEFAnkeK 348
Cdd:pfam04383  11 RRDKDGYINATKLCKAAGEKTKRFRNWLRLESTKELIEELEEEnnipkiitiigrkgkggrLQGTYVHPDLALAIA---S 87

                          90
                  ....*....|...
gi 2749600198 349 IIDLLFPLFVRDI 361
Cdd:pfam04383  88 WISPEFALKVSKI 100
PTZ00395 super family cl33180
Sec24-related protein; Provisional
 96-223 8.56e-03

Sec24-related protein; Provisional


The actual alignment was detected with superfamily member PTZ00395:

Pssm-ID: 185594 [Multi-domain]  Cd Length: 1560  Bit Score: 39.29  E-value: 8.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749600198   96 SFAAEQHASASHISNSSFPSAAGYPTSASYSSTQNSNTSNSNTSSNMYPYSQQPQYSSYYGNASHQYPGYQQANPSGSPQ 175
Cdd:PTZ00395   395 SNAAQSNAAQSNAGFSNAGYSNPGNSNPGYNNAPNSNTPYNNPPNSNTPYSNPPNSNPPYSNLPYSNTPYSNAPLSNAPP 474

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749600198  176 ATASPQ--------QHAPGGQPGG--ANTHLMYQQPMYGYSQPHV--PASSQSGGSAPYG 223
Cdd:PTZ00395   475 SSAKDHhsayhaayQHRAANQPAAnlPTANQPAANNFHGAAGNSVgnPFASRPFGSAPYG 534
 
Name Accession Description Interval E-value
KilA-N pfam04383
KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved ...
 287-361 1.47e-09

KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.


Pssm-ID: 367917  Cd Length: 107  Bit Score: 55.41  E-value: 1.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749600198 287 RREDNDMINGTKLLNVAGMTRGRRDGILKGEKLRHVVKAGAMH------------------LKGVWIPYDRALEFAnkeK 348
Cdd:pfam04383  11 RRDKDGYINATKLCKAAGEKTKRFRNWLRLESTKELIEELEEEnnipkiitiigrkgkggrLQGTYVHPDLALAIA---S 87

                          90
                  ....*....|...
gi 2749600198 349 IIDLLFPLFVRDI 361
Cdd:pfam04383  88 WISPEFALKVSKI 100
PTZ00395 PTZ00395
Sec24-related protein; Provisional
 96-223 8.56e-03

Sec24-related protein; Provisional


Pssm-ID: 185594 [Multi-domain]  Cd Length: 1560  Bit Score: 39.29  E-value: 8.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749600198   96 SFAAEQHASASHISNSSFPSAAGYPTSASYSSTQNSNTSNSNTSSNMYPYSQQPQYSSYYGNASHQYPGYQQANPSGSPQ 175
Cdd:PTZ00395   395 SNAAQSNAAQSNAGFSNAGYSNPGNSNPGYNNAPNSNTPYNNPPNSNTPYSNPPNSNPPYSNLPYSNTPYSNAPLSNAPP 474

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749600198  176 ATASPQ--------QHAPGGQPGG--ANTHLMYQQPMYGYSQPHV--PASSQSGGSAPYG 223
Cdd:PTZ00395   475 SSAKDHhsayhaayQHRAANQPAAnlPTANQPAANNFHGAAGNSVgnPFASRPFGSAPYG 534
 
Name Accession Description Interval E-value
KilA-N pfam04383
KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved ...
 287-361 1.47e-09

KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.


Pssm-ID: 367917  Cd Length: 107  Bit Score: 55.41  E-value: 1.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749600198 287 RREDNDMINGTKLLNVAGMTRGRRDGILKGEKLRHVVKAGAMH------------------LKGVWIPYDRALEFAnkeK 348
Cdd:pfam04383  11 RRDKDGYINATKLCKAAGEKTKRFRNWLRLESTKELIEELEEEnnipkiitiigrkgkggrLQGTYVHPDLALAIA---S 87

                          90
                  ....*....|...
gi 2749600198 349 IIDLLFPLFVRDI 361
Cdd:pfam04383  88 WISPEFALKVSKI 100
PTZ00395 PTZ00395
Sec24-related protein; Provisional
 96-223 8.56e-03

Sec24-related protein; Provisional


Pssm-ID: 185594 [Multi-domain]  Cd Length: 1560  Bit Score: 39.29  E-value: 8.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749600198   96 SFAAEQHASASHISNSSFPSAAGYPTSASYSSTQNSNTSNSNTSSNMYPYSQQPQYSSYYGNASHQYPGYQQANPSGSPQ 175
Cdd:PTZ00395   395 SNAAQSNAAQSNAGFSNAGYSNPGNSNPGYNNAPNSNTPYNNPPNSNTPYSNPPNSNPPYSNLPYSNTPYSNAPLSNAPP 474

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749600198  176 ATASPQ--------QHAPGGQPGG--ANTHLMYQQPMYGYSQPHV--PASSQSGGSAPYG 223
Cdd:PTZ00395   475 SSAKDHhsayhaayQHRAANQPAAnlPTANQPAANNFHGAAGNSVgnPFASRPFGSAPYG 534
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH