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Conserved domains on  [gi|48122105|ref|XP_396504|]
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serine-threonine kinase receptor-associated protein [Apis mellifera]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
5-297 2.60e-66

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 213.62  E-value: 2.60e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105   5 RQTPLTCSGHTRPVVHLAFSDiteSGYYLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWGVALNPQATRAASGAADFNA 84
Cdd:COG2319 110 GLLLRTLTGHTGAVRSVAFSP---DGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTV 186

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105  85 KVWDAIKGEEIHSFQ-HKHIVKSVNFSTDSNYLCTGSNEKLVRIYDLNKPdAAPQVFSGHKNGIRHVTFFNNNTALITCG 163
Cdd:COG2319 187 RLWDLATGKLLRTLTgHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATG-KLLRTLTGHSGSVRSVAFSPDGRLLASGS 265

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 164 DDKTLRVWDRNSGQEVKRLD-FPAIPNSMEVSRDGN-IITTTHSNIVTFWNSRELTKLREYTAPTQM-NSASLHPDCSIF 240
Cdd:COG2319 266 ADGTVRLWDLATGELLRTLTgHSGGVNSVAFSPDGKlLASGSDDGTVRLWDLATGKLLRTLTGHTGAvRSVAFSPDGKTL 345

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 48122105 241 VCGGEDLKMYKFDYTTGAEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTT 297
Cdd:COG2319 346 ASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLA 402
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
5-297 2.60e-66

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 213.62  E-value: 2.60e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105   5 RQTPLTCSGHTRPVVHLAFSDiteSGYYLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWGVALNPQATRAASGAADFNA 84
Cdd:COG2319 110 GLLLRTLTGHTGAVRSVAFSP---DGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTV 186

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105  85 KVWDAIKGEEIHSFQ-HKHIVKSVNFSTDSNYLCTGSNEKLVRIYDLNKPdAAPQVFSGHKNGIRHVTFFNNNTALITCG 163
Cdd:COG2319 187 RLWDLATGKLLRTLTgHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATG-KLLRTLTGHSGSVRSVAFSPDGRLLASGS 265

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 164 DDKTLRVWDRNSGQEVKRLD-FPAIPNSMEVSRDGN-IITTTHSNIVTFWNSRELTKLREYTAPTQM-NSASLHPDCSIF 240
Cdd:COG2319 266 ADGTVRLWDLATGELLRTLTgHSGGVNSVAFSPDGKlLASGSDDGTVRLWDLATGKLLRTLTGHTGAvRSVAFSPDGKTL 345

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 48122105 241 VCGGEDLKMYKFDYTTGAEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTT 297
Cdd:COG2319 346 ASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLA 402
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 10-295 1.16e-55

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 182.92  E-value: 1.16e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105  10 TCSGHTRPVVHLAFSDITEsgyYLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWGVALNPQATRAASGAADFNAKVWDA 89
Cdd:cd00200   4 TLKGHTGGVTCVAFSPDGK---LLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105  90 IKGEEIHSF-QHKHIVKSVNFSTDSNYLCTGSNEKLVRIYDLNKPDAApQVFSGHKNGIRHVTFFNNNTALITCGDDKTL 168
Cdd:cd00200  81 ETGECVRTLtGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCL-TTLRGHTDWVNSVAFSPDGTFVASSSQDGTI 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 169 RVWDRNSGQEVKRLDFPAIP-NSMEVSRDGN-IITTTHSNIVTFWNSRELTKLREYTAPTQ-MNSASLHPDCSIFVCGGE 245
Cdd:cd00200 160 KLWDLRTGKCVATLTGHTGEvNSVAFSPDGEkLLSSSSDGTIKLWDLSTGKCLGTLRGHENgVNSVAFSPDGYLLASGSE 239

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|
gi 48122105 246 DLKMYKFDYTTGAEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQ 295
Cdd:cd00200 240 DGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 256-294 3.86e-10

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 54.24  E-value: 3.86e-10
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 48122105    256 TGAEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 294
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 59-172 1.24e-09

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 59.33  E-value: 1.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105   59 HKGAVWGVALNP-QATRAASGAADFNAKVWDAIKGEEIHSFQHKHIVKSVNFSTDSNY-LCTGSNEKLVRIYDLNKPDAA 136
Cdd:PLN00181 574 HEKRVWSIDYSSaDPTLLASGSDDGSVKLWSINQGVSIGTIKTKANICCVQFPSESGRsLAFGSADHKVYYYDLRNPKLP 653

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 48122105  137 PQVFSGHKNGIRHVTFFNNNTaLITCGDDKTLRVWD 172
Cdd:PLN00181 654 LCTMIGHSKTVSYVRFVDSST-LVSSSTDNTLKLWD 688
WD40 pfam00400
WD domain, G-beta repeat;
257-294 2.99e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 51.96  E-value: 2.99e-09
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 48122105   257 GAEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 294
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
5-297 2.60e-66

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 213.62  E-value: 2.60e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105   5 RQTPLTCSGHTRPVVHLAFSDiteSGYYLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWGVALNPQATRAASGAADFNA 84
Cdd:COG2319 110 GLLLRTLTGHTGAVRSVAFSP---DGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTV 186

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105  85 KVWDAIKGEEIHSFQ-HKHIVKSVNFSTDSNYLCTGSNEKLVRIYDLNKPdAAPQVFSGHKNGIRHVTFFNNNTALITCG 163
Cdd:COG2319 187 RLWDLATGKLLRTLTgHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATG-KLLRTLTGHSGSVRSVAFSPDGRLLASGS 265

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 164 DDKTLRVWDRNSGQEVKRLD-FPAIPNSMEVSRDGN-IITTTHSNIVTFWNSRELTKLREYTAPTQM-NSASLHPDCSIF 240
Cdd:COG2319 266 ADGTVRLWDLATGELLRTLTgHSGGVNSVAFSPDGKlLASGSDDGTVRLWDLATGKLLRTLTGHTGAvRSVAFSPDGKTL 345

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 48122105 241 VCGGEDLKMYKFDYTTGAEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTT 297
Cdd:COG2319 346 ASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLA 402
WD40 COG2319
WD40 repeat [General function prediction only];
5-300 2.68e-61

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 200.91  E-value: 2.68e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105   5 RQTPLTCSGHTRPVVHLAFSDiteSGYYLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWGVALNPQATRAASGAADFNA 84
Cdd:COG2319  68 GALLATLLGHTAAVLSVAFSP---DGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTV 144

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105  85 KVWDAIKGEEIHSFQ-HKHIVKSVNFSTDSNYLCTGSNEKLVRIYDLNKpDAAPQVFSGHKNGIRHVTFFNNNTALITCG 163
Cdd:COG2319 145 RLWDLATGKLLRTLTgHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLAT-GKLLRTLTGHTGAVRSVAFSPDGKLLASGS 223

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 164 DDKTLRVWDRNSGQEVKRLDFPAIP-NSMEVSRDGNII-TTTHSNIVTFWNSRELTKLREYTAPTQ-MNSASLHPDCSIF 240
Cdd:COG2319 224 ADGTVRLWDLATGKLLRTLTGHSGSvRSVAFSPDGRLLaSGSADGTVRLWDLATGELLRTLTGHSGgVNSVAFSPDGKLL 303

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 241 VCGGEDLKMYKFDYTTGAEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTVGK 300
Cdd:COG2319 304 ASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGE 363
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 10-295 1.16e-55

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 182.92  E-value: 1.16e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105  10 TCSGHTRPVVHLAFSDITEsgyYLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWGVALNPQATRAASGAADFNAKVWDA 89
Cdd:cd00200   4 TLKGHTGGVTCVAFSPDGK---LLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105  90 IKGEEIHSF-QHKHIVKSVNFSTDSNYLCTGSNEKLVRIYDLNKPDAApQVFSGHKNGIRHVTFFNNNTALITCGDDKTL 168
Cdd:cd00200  81 ETGECVRTLtGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCL-TTLRGHTDWVNSVAFSPDGTFVASSSQDGTI 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 169 RVWDRNSGQEVKRLDFPAIP-NSMEVSRDGN-IITTTHSNIVTFWNSRELTKLREYTAPTQ-MNSASLHPDCSIFVCGGE 245
Cdd:cd00200 160 KLWDLRTGKCVATLTGHTGEvNSVAFSPDGEkLLSSSSDGTIKLWDLSTGKCLGTLRGHENgVNSVAFSPDGYLLASGSE 239

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|
gi 48122105 246 DLKMYKFDYTTGAEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQ 295
Cdd:cd00200 240 DGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 53-301 5.98e-51

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 170.59  E-value: 5.98e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105  53 IGTFEGHKGAVWGVALNPQATRAASGAADFNAKVWDAIKGEEIHSFQ-HKHIVKSVNFSTDSNYLCTGSNEKLVRIYDLN 131
Cdd:cd00200   2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKgHTGPVRDVAASADGTYLASGSSDKTIRLWDLE 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 132 KPDAApQVFSGHKNGIRHVTFFNNNTALITCGDDKTLRVWDRNSGQEVKRLDFPAIP-NSMEVSRDGNIITT-THSNIVT 209
Cdd:cd00200  82 TGECV-RTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWvNSVAFSPDGTFVASsSQDGTIK 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 210 FWNSRELTKLREYTAPT-QMNSASLHPDCSIFVCGGEDLKMYKFDYTTGAEIESFKGHFGPVHCVRFSPDGELYASGSED 288
Cdd:cd00200 161 LWDLRTGKCVATLTGHTgEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSED 240

                       250
                ....*....|...
gi 48122105 289 GTLRLWQTTVGKT 301
Cdd:cd00200 241 GTIRVWDLRTGEC 253
WD40 COG2319
WD40 repeat [General function prediction only];
44-300 2.11e-45

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 159.31  E-value: 2.11e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105  44 LRQGDTGDWIGTFEGHKGAVWGVALNPQATRAASGAADFNAKVWDAIKGEEIHSFQ-HKHIVKSVNFSTDSNYLCTGSNE 122
Cdd:COG2319  20 LLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLgHTAAVLSVAFSPDGRLLASASAD 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 123 KLVRIYDLNKPdAAPQVFSGHKNGIRHVTFFNNNTALITCGDDKTLRVWDRNSGQEVKRLDFPAIP-NSMEVSRDGNIIT 201
Cdd:COG2319 100 GTVRLWDLATG-LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAvTSVAFSPDGKLLA 178

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 202 TTHS-NIVTFWNSRELTKLREYTAPTQM-NSASLHPDCSIFVCGGED--LKMYkfDYTTGAEIESFKGHFGPVHCVRFSP 277
Cdd:COG2319 179 SGSDdGTVRLWDLATGKLLRTLTGHTGAvRSVAFSPDGKLLASGSADgtVRLW--DLATGKLLRTLTGHSGSVRSVAFSP 256

                       250       260
                ....*....|....*....|...
gi 48122105 278 DGELYASGSEDGTLRLWQTTVGK 300
Cdd:COG2319 257 DGRLLASGSADGTVRLWDLATGE 279
WD40 COG2319
WD40 repeat [General function prediction only];
5-175 1.36e-34

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 130.42  E-value: 1.36e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105   5 RQTPLTCSGHTRPVVHLAFSDiteSGYYLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWGVALNPQATRAASGAADFNA 84
Cdd:COG2319 236 GKLLRTLTGHSGSVRSVAFSP---DGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTV 312

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105  85 KVWDAIKGEEIHSFQ-HKHIVKSVNFSTDSNYLCTGSNEKLVRIYDLNKPdAAPQVFSGHKNGIRHVTFFNNNTALITCG 163
Cdd:COG2319 313 RLWDLATGKLLRTLTgHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATG-ELLRTLTGHTGAVTSVAFSPDGRTLASGS 391

                       170
                ....*....|..
gi 48122105 164 DDKTLRVWDRNS 175
Cdd:COG2319 392 ADGTVRLWDLAT 403
WD40 COG2319
WD40 repeat [General function prediction only];
2-89 6.68e-12

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 65.70  E-value: 6.68e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105   2 ANLRQTPLTCSGHTRPVVHLAFSDiteSGYYLISACKDGKPMLRQGDTGDWIGTFEGHKGAVWGVALNPQATRAASGAAD 81
Cdd:COG2319 317 LATGKLLRTLTGHTGAVRSVAFSP---DGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSAD 393


                ....*...
gi 48122105  82 FNAKVWDA 89
Cdd:COG2319 394 GTVRLWDL 401
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 256-294 3.86e-10

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 54.24  E-value: 3.86e-10
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 48122105    256 TGAEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 294
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 59-172 1.24e-09

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 59.33  E-value: 1.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105   59 HKGAVWGVALNP-QATRAASGAADFNAKVWDAIKGEEIHSFQHKHIVKSVNFSTDSNY-LCTGSNEKLVRIYDLNKPDAA 136
Cdd:PLN00181 574 HEKRVWSIDYSSaDPTLLASGSDDGSVKLWSINQGVSIGTIKTKANICCVQFPSESGRsLAFGSADHKVYYYDLRNPKLP 653

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 48122105  137 PQVFSGHKNGIRHVTFFNNNTaLITCGDDKTLRVWD 172
Cdd:PLN00181 654 LCTMIGHSKTVSYVRFVDSST-LVSSSTDNTLKLWD 688
WD40 pfam00400
WD domain, G-beta repeat;
257-294 2.99e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 51.96  E-value: 2.99e-09
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 48122105   257 GAEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 294
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
146-290 3.01e-09

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 56.63  E-value: 3.01e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105 146 GIRHVTFFNNNTALITCGDDKTLRVWDRNSGQEVKRLDFPAIPNSMEVSRDGN--IITTTHSNIVTFWNSRELTKLREYT 223
Cdd:COG3391  70 ADGADAGADGRRLYVANSGSGRVSVIDLATGKVVATIPVGGGPRGLAVDPDGGrlYVADSGNGRVSVIDTATGKVVATIP 149

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 48122105 224 APTQMNSASLHPDCS-IFVCGGEDLKM----YKFDYTTGAEIESFKGHFGPVHcVRFSPDG-ELYASGSEDGT 290
Cdd:COG3391 150 VGAGPHGIAVDPDGKrLYVANSGSNTVsvivSVIDTATGKVVATIPVGGGPVG-VAVSPDGrRLYVANRGSNT 221
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 138-172 3.88e-07

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 45.77  E-value: 3.88e-07
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 48122105    138 QVFSGHKNGIRHVTFFNNNTALITCGDDKTLRVWD 172
Cdd:smart00320   6 KTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
138-172 1.45e-06

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 44.26  E-value: 1.45e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 48122105   138 QVFSGHKNGIRHVTFFNNNTALITCGDDKTLRVWD 172
Cdd:pfam00400   5 KTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 49-88 1.00e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 41.91  E-value: 1.00e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 48122105     49 TGDWIGTFEGHKGAVWGVALNPQATRAASGAADFNAKVWD 88
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
53-88 2.00e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 41.18  E-value: 2.00e-05
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 48122105    53 IGTFEGHKGAVWGVALNPQATRAASGAADFNAKVWD 88
Cdd:pfam00400   4 LKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 91-129 6.41e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 39.60  E-value: 6.41e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 48122105     91 KGEEIHSFQ-HKHIVKSVNFSTDSNYLCTGSNEKLVRIYD 129
Cdd:smart00320   1 SGELLKTLKgHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
PTZ00421 PTZ00421
coronin; Provisional
 13-129 2.22e-04

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 42.96  E-value: 2.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48122105   13 GHTRPVVHLAFSDITESGyyLISACKDGKPM--------LRQgDTGDWIGTFEGHKGAVWGVALNPQATRA-ASGAADFN 83
Cdd:PTZ00421  73 GQEGPIIDVAFNPFDPQK--LFTASEDGTIMgwgipeegLTQ-NISDPIVHLQGHTKKVGIVSFHPSAMNVlASAGADMV 149

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 48122105   84 AKVWDAIKGEEIHSFQ-HKHIVKSVNFSTDSNYLCTGSNEKLVRIYD 129
Cdd:PTZ00421 150 VNVWDVERGKAVEVIKcHSDQITSLEWNLDGSLLCTTSKDKKLNIID 196
WD40 pfam00400
WD domain, G-beta repeat;
92-129 3.97e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 37.32  E-value: 3.97e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 48122105    92 GEEIHSFQ-HKHIVKSVNFSTDSNYLCTGSNEKLVRIYD 129
Cdd:pfam00400   1 GKLLKTLEgHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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