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Conserved domains on  [gi|2490696982|ref|XP_054964656|]
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complement decay-accelerating factor isoform X9 [Pan paniscus]

Protein Classification

beta-2-glycoprotein 1( domain architecture ID 13884057)

beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 98-280 8.62e-36

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 132.08  E-value: 8.62e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982  98 CEVPTRLNSASLK---QPYITQNYfPVGTVVEYECRPGYRREPSLSTKLTCLQNlKWsTAVEFCKKKSCPNPGEIRNGQI 174
Cdd:PHA02927   21 CTIPSRPINMKFKnsvETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GW-TLFNQCIKRRCPSPRDIDNGQL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 175 DVpDGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQWSDPLPECREIHCPAPPQIDNGIIQGERDHYGYRQSVTYAC 253
Cdd:PHA02927   98 DI-GGVDFGSSITYSCNSGYQLIGESKSYCeLGSTGSMVWNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSC 176

                         170       180
                  ....*....|....*....|....*..
gi 2490696982 254 NKGFTMIGEHSIYCTvnndEGEWSGPP 280
Cdd:PHA02927  177 NSGYSLIGNSGVLCS----GGEWSDPP 199
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 36-94 7.03e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 40.20  E-value: 7.03e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2490696982   36 CGLPPEVPNAQPALeGRTSFPEDTVITYKCEESFVKIPGEkdSVICLKGSQWSDIEEFC 94
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPGYTLIGSS--TITCLENGTWSPPPPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 98-280 8.62e-36

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 132.08  E-value: 8.62e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982  98 CEVPTRLNSASLK---QPYITQNYfPVGTVVEYECRPGYRREPSLSTKLTCLQNlKWsTAVEFCKKKSCPNPGEIRNGQI 174
Cdd:PHA02927   21 CTIPSRPINMKFKnsvETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GW-TLFNQCIKRRCPSPRDIDNGQL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 175 DVpDGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQWSDPLPECREIHCPAPPQIDNGIIQGERDHYGYRQSVTYAC 253
Cdd:PHA02927   98 DI-GGVDFGSSITYSCNSGYQLIGESKSYCeLGSTGSMVWNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSC 176

                         170       180
                  ....*....|....*....|....*..
gi 2490696982 254 NKGFTMIGEHSIYCTvnndEGEWSGPP 280
Cdd:PHA02927  177 NSGYSLIGNSGVLCS----GGEWSDPP 199
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 225-284 7.42e-16

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 71.34  E-value: 7.42e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNndeGEWSGPPPECR 284
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN---GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 225-283 5.55e-13

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 63.31  E-value: 5.55e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2490696982  225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTvnnDEGEWSGPPPEC 283
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL---ENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
225-283 3.87e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 60.98  E-value: 3.87e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2490696982 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTvnnDEGEWSGPPPEC 283
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQ---EDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 36-94 7.03e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 40.20  E-value: 7.03e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2490696982   36 CGLPPEVPNAQPALeGRTSFPEDTVITYKCEESFVKIPGEkdSVICLKGSQWSDIEEFC 94
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPGYTLIGSS--TITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 36-94 2.50e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 38.60  E-value: 2.50e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2490696982  36 CGLPPEVPNAQPALeGRTSFPEDTVITYKCEESFVKIPgeKDSVICLKGSQWSDIEEFC 94
Cdd:cd00033     1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 98-280 8.62e-36

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 132.08  E-value: 8.62e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982  98 CEVPTRLNSASLK---QPYITQNYfPVGTVVEYECRPGYRREPSLSTKLTCLQNlKWsTAVEFCKKKSCPNPGEIRNGQI 174
Cdd:PHA02927   21 CTIPSRPINMKFKnsvETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GW-TLFNQCIKRRCPSPRDIDNGQL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 175 DVpDGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQWSDPLPECREIHCPAPPQIDNGIIQGERDHYGYRQSVTYAC 253
Cdd:PHA02927   98 DI-GGVDFGSSITYSCNSGYQLIGESKSYCeLGSTGSMVWNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSC 176

                         170       180
                  ....*....|....*....|....*..
gi 2490696982 254 NKGFTMIGEHSIYCTvnndEGEWSGPP 280
Cdd:PHA02927  177 NSGYSLIGNSGVLCS----GGEWSDPP 199
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 225-284 7.42e-16

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 71.34  E-value: 7.42e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNndeGEWSGPPPECR 284
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN---GGWSPPPPTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
 159-284 1.29e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 70.85  E-value: 1.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 159 KKKSCPNPGEIRNGQI-DVPDGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIHCPAPPQIDNGIIQ 237
Cdd:PHA02639   18 KSIYCDKPDDISNGFItELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIY 97

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2490696982 238 GERDHYGYRQSVTYACN--KG--FTMIGEHSIYCTvnnDEGEWSGPPPECR 284
Cdd:PHA02639   98 NKREMYKVGDEIYYVCNehKGvqYSLVGNEKITCI---QDKSWKPDPPICK 145
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 225-283 5.55e-13

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 63.31  E-value: 5.55e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2490696982  225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTvnnDEGEWSGPPPEC 283
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL---ENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
225-283 3.87e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 60.98  E-value: 3.87e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2490696982 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTvnnDEGEWSGPPPEC 283
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQ---EDGTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 119-291 1.13e-11

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 65.07  E-value: 1.13e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 119 FPVGTVVEYECRPGYrrePSLSTKL-TCLQ---NLKWSTAVEFCKKKSCPNPGEIRNGQI-DVPDGILFGATISFSCN-- 191
Cdd:PHA02639   40 YEIGKLIEYTCNTDY---ALIGDRFrTCIKdknNAIWSNKAPFCMLKECNDPPSIINGKIyNKREMYKVGDEIYYVCNeh 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 192 --TGYKLFGSTSSFCLISGSsvqWSDPLPECREIHCPApPQIDNGIIQG--ERDHYGYRQSVTYACNKGFTMIGEHSIYC 267
Cdd:PHA02639  117 kgVQYSLVGNEKITCIQDKS---WKPDPPICKMINCRF-PALQNGYINGipSNKKFYYKTRVGFSCKSGFDLVGEKYSTC 192

                         170       180
                  ....*....|....*....|....
gi 2490696982 268 TVNndeGEWSGPPPECraTRSTPV 291
Cdd:PHA02639  193 NIN---ATWFPSIPTC--VRNKPI 211
PHA02831 PHA02831
EEV host range protein; Provisional
 125-283 2.74e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 63.47  E-value: 2.74e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 125 VEYECRPGYRrepslSTKLTClQNLKWSTAVEFCKKKSCPNPGEIRNGQI-DVPDGILFGATISFSCNTG----YKLFGS 199
Cdd:PHA02831   46 LEYKCNNNFD-----KVFVTC-NNGSWSTKNMCIGKRNCKDPVTILNGYIkNKKDQYSFGDSVTYACKVNklekYSIVGN 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 200 TSSFClISGssvQWSDPLPECREIHCPAPPqIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNdegEWSGP 279
Cdd:PHA02831  120 ETVKC-INK---QWVPKYPVCKLIRCKYPA-LQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINS---IWYPG 191


                  ....
gi 2490696982 280 PPEC 283
Cdd:PHA02831  192 IPKC 195
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 163-221 1.63e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.32  E-value: 1.63e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 163 CPNPGEIRNGQIDVPDGI-LFGATISFSCNTGYKLFGSTSSFCLISGssvQWSDPLPECR 221
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSySYGSTVTYSCNEGYTLVGSSTITCTENG---GWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
98-158 2.91e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 55.58  E-value: 2.91e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2490696982  98 CEVPTRLNSASLkqpYITQNYFPVGTVVEYECRPGYRREPSLstKLTCLQNLKWSTAVEFC 158
Cdd:pfam00084   1 CPPPPDIPNGKV---SATKNEYNYGASVSYECDPGYRLVGSP--TITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 163-220 2.39e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.91  E-value: 2.39e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2490696982  163 CPNPGEIRNGQIDVPDG-ILFGATISFSCNTGYKLFGSTSSFCLISGssvQWSDPLPEC 220
Cdd:smart00032   1 CPPPPDIENGTVTSSSGtYSYGDTVTYSCDPGYTLIGSSTITCLENG---TWSPPPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 157-283 1.73e-08

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 54.56  E-value: 1.73e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 157 FCKKKSCPNPGEIRNGQI-DVPDGILFGATISFSCNTG-----YKLFGSTSSFCLISGssvQWSDPLPECREIHCPAPPq 230
Cdd:PHA02817   18 LCDLNKCCYPPSIKNGYIyNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDG---KWNKEFPVCKIIRCRFPA- 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2490696982 231 IDNGIIQGERDH--YGYRQSVTYACNKGFTMIGEHSIYCTVNNdegEWSGPPPEC 283
Cdd:PHA02817   94 LQNGFVNGIPDSkkFYYESEVSFSCKPGFVLIGTKYSVCGINS---SWIPKVPIC 145
Sushi pfam00084
Sushi repeat (SCR repeat);
163-220 5.00e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.64  E-value: 5.00e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2490696982 163 CPNPGEIRNGQIDVPDGI-LFGATISFSCNTGYKLFGSTSSFCLISGssvQWSDPLPEC 220
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEyNYGASVSYECDPGYRLVGSPTITCQEDG---TWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 98-159 5.30e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.61  E-value: 5.30e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2490696982  98 CEVPTRLNSASLKqpyITQNYFPVGTVVEYECRPGYRREPslSTKLTCLQNLKWSTAVEFCK 159
Cdd:cd00033     1 CPPPPVPENGTVT---GSKGSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
 220-287 7.53e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.86  E-value: 7.53e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2490696982 220 CREIHCPAPPQIDNGIIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCtvnNDEGEWSGPPPECRATR 287
Cdd:PHA02817   19 CDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIIC---EKDGKWNKEFPVCKIIR 88
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 115-158 2.46e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 41.74  E-value: 2.46e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 2490696982  115 TQNYFPVGTVVEYECRPGYRREPslSTKLTCLQNLKWSTAVEFC 158
Cdd:smart00032  15 SSGTYSYGDTVTYSCDPGYTLIG--SSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 36-94 7.03e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 40.20  E-value: 7.03e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2490696982   36 CGLPPEVPNAQPALeGRTSFPEDTVITYKCEESFVKIPGEkdSVICLKGSQWSDIEEFC 94
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPGYTLIGSS--TITCLENGTWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 186-287 2.16e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 42.67  E-value: 2.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 186 ISFSCNTGYKlfgstSSFCLISGSSvqWSDPLPECREIHCPAPPQIDNGIIQGERDHYGYRQSVTYAC--NK--GFTMIG 261
Cdd:PHA02831   46 LEYKCNNNFD-----KVFVTCNNGS--WSTKNMCIGKRNCKDPVTILNGYIKNKKDQYSFGDSVTYACkvNKleKYSIVG 118

                          90       100
                  ....*....|....*....|....*.
gi 2490696982 262 EHSIYCTvnndEGEWSGPPPECRATR 287
Cdd:PHA02831  119 NETVKCI----NKQWVPKYPVCKLIR 140
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 36-94 2.50e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 38.60  E-value: 2.50e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2490696982  36 CGLPPEVPNAQPALeGRTSFPEDTVITYKCEESFVKIPgeKDSVICLKGSQWSDIEEFC 94
Cdd:cd00033     1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 97-271 5.35e-04

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 41.61  E-value: 5.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982  97 SCEVPTrLNSASLKQpyiTQNYFPVGTVVEYECRPGYRrepSLSTKLTClQNLKWStaVEFCKKKSCPNPGEIRngqiDV 176
Cdd:PHA02954   20 TCTVPT-MNNAKLTS---TETSFNDKQKVTFTCDSGYY---SLDPNAVC-ETDKWK--YENPCKKMCTVSDYVS----EL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490696982 177 PDGILF--GATISFSCNTGYKLFGstssfCLISGSSVQWSDPLpECREIHCpAPPQIDNGIIQGERDHYGYRQSVTYACN 254
Cdd:PHA02954   86 YDKPLYevNSTITLICKDETKYFR-----CEEKNGNTSWNDTV-TCPNAEC-QPLQLEHGSCQPVKEKYSFGEHITINCD 158

                         170
                  ....*....|....*..
gi 2490696982 255 KGFTMIGEHSIYCTVNN 271
Cdd:PHA02954  159 VGYEVIGASYISCTANS 175
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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