|
Name |
Accession |
Description |
Interval |
E-value |
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
112-296 |
3.41e-43 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 154.94 E-value: 3.41e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 112 LYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENL 191
Cdd:cd21340 7 LYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 192 SCLPVLNTLQM------------------------------AHNHLETVEDIQHLQeclRLCVLDLSHNKLSD-PEILSI 240
Cdd:cd21340 87 ENLTNLEELHIenqrlppgekltfdprslaalsnslrvlniSGNNIDSLEPLAPLR---NLEQLDASNNQISDlEELLDL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2462547415 241 LESMPDLRVLNLMGNPVIRQiPNYRRTVTVRLKHLTYLDDRPVFPKDRACAEAWAR 296
Cdd:cd21340 164 LSSWPSLRELDLTGNPVCKK-PKYRDKIILASKSLEVLDGKEITDTERQFLKRLKA 218
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
111-279 |
1.13e-19 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 91.92 E-value: 1.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 111 TLYLHFKGFDRI-ENLEEYTGLRCLWLQSNGIQKI-ENLEAQTELRCLFLQMNLLRKI-ENLEPLQKLDALNLSNNYIKT 187
Cdd:COG4886 117 SLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSNNQITD 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 188 I-ENLSCLPVLNTLQMAHNHLETVEDIqhLQECLRLCVLDLSHNKLSDpeiLSILESMPDLRVLNLMGNPvIRQIPNyrr 266
Cdd:COG4886 197 LpEPLGNLTNLEELDLSGNQLTDLPEP--LANLTNLETLDLSNNQLTD---LPELGNLTNLEELDLSNNQ-LTDLPP--- 267
|
170
....*....|...
gi 2462547415 267 tvTVRLKHLTYLD 279
Cdd:COG4886 268 --LANLTNLKTLD 278
|
|
| LRR_9 |
pfam14580 |
Leucine-rich repeat; |
166-302 |
1.46e-11 |
|
Leucine-rich repeat;
Pssm-ID: 405295 [Multi-domain] Cd Length: 175 Bit Score: 63.63 E-value: 1.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 166 IENL-EPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNH-LETVEDIQHLQECLRlcVLDLSHNKLSDPEILSILES 243
Cdd:pfam14580 34 IENLgATLDQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRiCRIGEGLGEALPNLT--ELILTNNNLQELGDLDPLAS 111
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 2462547415 244 MPDLRVLNLMGNPVIRQiPNYRRTVTVRLKHLTYLDDRPVFPKDRACAEAWARGGYAAE 302
Cdd:pfam14580 112 LKKLTFLSLLRNPVTNK-PHYRLYVIYKVPQLRLLDFRKVKQKERQAAEKMFRSKQGKQ 169
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
173-274 |
6.58e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 42.91 E-value: 6.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 173 QKLDALNLSNNYIKTI--ENLSCLPVLNTLQMAHNHLeTVEDIQHLQECLRLCVLDLSHNKLSDpEILSILESMPDLRVL 250
Cdd:PLN00113 475 KRLENLDLSRNQFSGAvpRKLGSLSELMQLKLSENKL-SGEIPDELSSCKKLVSLDLSHNQLSG-QIPASFSEMPVLSQL 552
|
90 100
....*....|....*....|....*...
gi 2462547415 251 NLMGNPVIRQIP----NYRRTVTVRLKH 274
Cdd:PLN00113 553 DLSQNQLSGEIPknlgNVESLVQVNISH 580
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
296-508 |
8.03e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 42.27 E-value: 8.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 296 RGGYAAEKEERQQWESRERK-KITDSIEALAMIKQRAEERKRQRESQERGmrsAEDNSPRVPLRLGEMTSSDDGENvpas 374
Cdd:PHA03169 26 HGGTREQAGRRRGTAARAAKpAPPAPTTSGPQVRAVAEQGHRQTESDTET---AEESRHGEKEERGQGGPSGSGSE---- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 375 aEGKEEPPGDRETRQkmELFVKESFEAKEELCPEKPSGEEPPvEAKREDGGP----EPEGTLPAETLLLSSPVEVKGEDG 450
Cdd:PHA03169 99 -SVGSPTPSPSGSAE--ELASGLSPENTSGSSPESPASHSPP-PSPPSHPGPhepaPPESHNPSPNQQPSSFLQPSHEDS 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2462547415 451 DGEPEGtlPAEAPPPPPPVEVKGEDGDQEPEGTLPAETlllsppvkvKGEDGDREPEG 508
Cdd:PHA03169 175 PEEPEP--PTSEPEPDSPGPPQSETPTSSPPPQSPPDE---------PGEPQSPTPQQ 221
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
112-296 |
3.41e-43 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 154.94 E-value: 3.41e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 112 LYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENL 191
Cdd:cd21340 7 LYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 192 SCLPVLNTLQM------------------------------AHNHLETVEDIQHLQeclRLCVLDLSHNKLSD-PEILSI 240
Cdd:cd21340 87 ENLTNLEELHIenqrlppgekltfdprslaalsnslrvlniSGNNIDSLEPLAPLR---NLEQLDASNNQISDlEELLDL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2462547415 241 LESMPDLRVLNLMGNPVIRQiPNYRRTVTVRLKHLTYLDDRPVFPKDRACAEAWAR 296
Cdd:cd21340 164 LSSWPSLRELDLTGNPVCKK-PKYRDKIILASKSLEVLDGKEITDTERQFLKRLKA 218
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
111-279 |
1.13e-19 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 91.92 E-value: 1.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 111 TLYLHFKGFDRI-ENLEEYTGLRCLWLQSNGIQKI-ENLEAQTELRCLFLQMNLLRKI-ENLEPLQKLDALNLSNNYIKT 187
Cdd:COG4886 117 SLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSNNQITD 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 188 I-ENLSCLPVLNTLQMAHNHLETVEDIqhLQECLRLCVLDLSHNKLSDpeiLSILESMPDLRVLNLMGNPvIRQIPNyrr 266
Cdd:COG4886 197 LpEPLGNLTNLEELDLSGNQLTDLPEP--LANLTNLETLDLSNNQLTD---LPELGNLTNLEELDLSNNQ-LTDLPP--- 267
|
170
....*....|...
gi 2462547415 267 tvTVRLKHLTYLD 279
Cdd:COG4886 268 --LANLTNLKTLD 278
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
89-279 |
8.00e-19 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 89.22 E-value: 8.00e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 89 TKSSLQKLCKQHKLYITPALNDTLYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKI-ENLEAQTELRCLFLQMNLLRKI- 166
Cdd:COG4886 73 LLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLp 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 167 ENLEPLQKLDALNLSNNYIKTI-ENLSCLPVLNTLQMAHNHLETVEDiqHLQECLRLCVLDLSHNKLSDpeILSILESMP 245
Cdd:COG4886 153 EPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSNNQITDLPE--PLGNLTNLEELDLSGNQLTD--LPEPLANLT 228
|
170 180 190
....*....|....*....|....*....|....
gi 2462547415 246 DLRVLNLMGNPvIRQIPNYRrtvtvRLKHLTYLD 279
Cdd:COG4886 229 NLETLDLSNNQ-LTDLPELG-----NLTNLEELD 256
|
|
| LRR_9 |
pfam14580 |
Leucine-rich repeat; |
166-302 |
1.46e-11 |
|
Leucine-rich repeat;
Pssm-ID: 405295 [Multi-domain] Cd Length: 175 Bit Score: 63.63 E-value: 1.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 166 IENL-EPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNH-LETVEDIQHLQECLRlcVLDLSHNKLSDPEILSILES 243
Cdd:pfam14580 34 IENLgATLDQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRiCRIGEGLGEALPNLT--ELILTNNNLQELGDLDPLAS 111
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 2462547415 244 MPDLRVLNLMGNPVIRQiPNYRRTVTVRLKHLTYLDDRPVFPKDRACAEAWARGGYAAE 302
Cdd:pfam14580 112 LKKLTFLSLLRNPVTNK-PHYRLYVIYKVPQLRLLDFRKVKQKERQAAEKMFRSKQGKQ 169
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
111-263 |
1.45e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 63.80 E-value: 1.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 111 TLYLHFKGFDRI-ENLEEYTGLRCLWLQSNGIQKI-ENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTI 188
Cdd:COG4886 186 ELDLSNNQITDLpEPLGNLTNLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDL 265
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462547415 189 ENLSCLPVLNTLQMAHNHLETVEdIQHLQECLRLCVLDLSHNKLSDPEILSILESMPDLRVLNLMGNPVIRQIPN 263
Cdd:COG4886 266 PPLANLTNLKTLDLSNNQLTDLK-LKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTT 339
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
91-279 |
2.26e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 59.95 E-value: 2.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 91 SSLQKLCKQHKLYITPALNDTLYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLE 170
Cdd:COG4886 14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 171 PLQKLDALNLSNNyiktiENLSCLPVLNTLQMAHNHLETV-EDIQHLQEcLRlcVLDLSHNKLSDpeILSILESMPDLRV 249
Cdd:COG4886 94 DLTNLTELDLSGN-----EELSNLTNLESLDLSGNQLTDLpEELANLTN-LK--ELDLSNNQLTD--LPEPLGNLTNLKS 163
|
170 180 190
....*....|....*....|....*....|
gi 2462547415 250 LNLMGNPvIRQIPNyrrtVTVRLKHLTYLD 279
Cdd:COG4886 164 LDLSNNQ-LTDLPE----ELGNLTNLKELD 188
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
221-265 |
3.19e-07 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 47.24 E-value: 3.19e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 2462547415 221 RLCVLDLSHNKLSDpeiLSILESMPDLRVLNLMGNPVIRQIPNYR 265
Cdd:pfam12799 2 NLEVLDLSNNQITD---IPPLAKLPNLETLDLSGNNKITDLSDLA 43
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
151-207 |
1.10e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 1.10e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462547415 151 TELRCLFLQMNLLRKI--ENLEPLQKLDALNLSNNYIKTIEN--LSCLPVLNTLQMAHNHL 207
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLddGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
151-192 |
1.18e-05 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 42.62 E-value: 1.18e-05
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 2462547415 151 TELRCLFLQMNLLRKIENLEPLQKLDALNLS-NNYIKTIENLS 192
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSgNNKITDLSDLA 43
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
122-255 |
1.39e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.86 E-value: 1.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 122 IENLEEYTGLRCLWLQSNGIQK------IENLEAQTELRCLFLQMN------LLRKIENLEPLQKLDALNLSNNYIKT-- 187
Cdd:COG5238 229 AEALKGNKSLTTLDLSNNQIGDegvialAEALKNNTTVETLYLSGNqigaegAIALAKALQGNTTLTSLDLSVNRIGDeg 308
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462547415 188 ----IENLSCLPVLNTLQMAHNHLETVEDI---QHLQECLRLCVLDLSHNKLSDP---EILSILESMPDLRVLNLMGN 255
Cdd:COG5238 309 aialAEGLQGNKTLHTLNLAYNGIGAQGAIalaKALQENTTLHSLDLSDNQIGDEgaiALAKYLEGNTTLRELNLGKN 386
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
102-279 |
1.45e-05 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 48.01 E-value: 1.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 102 LYITPALNDTLYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLS 181
Cdd:COG4886 6 LSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 182 NNYIKTIENLSCLPVLNtlqmahnhLETVEDIQHLQEclrLCVLDLSHNKLSD-PEILSileSMPDLRVLNLMGNPvIRQ 260
Cdd:COG4886 86 LLGLTDLGDLTNLTELD--------LSGNEELSNLTN---LESLDLSGNQLTDlPEELA---NLTNLKELDLSNNQ-LTD 150
|
170
....*....|....*....
gi 2462547415 261 IPnyrrTVTVRLKHLTYLD 279
Cdd:COG4886 151 LP----EPLGNLTNLKSLD 165
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
195-257 |
2.13e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.51 E-value: 2.13e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462547415 195 PVLNTLQMAHNHLETVED--IQHLQeclRLCVLDLSHNKLS--DPEILSileSMPDLRVLNLMGNPV 257
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDgaFKGLS---NLKVLDLSNNLLTtlSPGAFS---GLPSLRYLDLSGNRL 61
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
173-218 |
3.84e-05 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 41.08 E-value: 3.84e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 2462547415 173 QKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLetVEDIQHLQE 218
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNNK--ITDLSDLAN 44
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
129-174 |
1.36e-04 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 39.54 E-value: 1.36e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 2462547415 129 TGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNllRKIENLEPLQK 174
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGN--NKITDLSDLAN 44
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
122-257 |
3.42e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 43.11 E-value: 3.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 122 IENLEEYTGLRCLWLQSNGIQK-----IENLEAQTELRCLFLQMNLLRK------IENLEPLQ-KLDALNLSNNyikTIE 189
Cdd:cd00116 74 LQGLTKGCGLQELDLSDNALGPdgcgvLESLLRSSSLQELKLNNNGLGDrglrllAKGLKDLPpALEKLVLGRN---RLE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 190 NLSC---------LPVLNTLQMAHNHLeTVEDIQHLQECLR----LCVLDLSHNKLSDPEILSI---LESMPDLRVLNLM 253
Cdd:cd00116 151 GASCealakalraNRDLKELNLANNGI-GDAGIRALAEGLKancnLEVLDLNNNGLTDEGASALaetLASLKSLEVLNLG 229
|
....
gi 2462547415 254 GNPV 257
Cdd:cd00116 230 DNNL 233
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
173-274 |
6.58e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 42.91 E-value: 6.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 173 QKLDALNLSNNYIKTI--ENLSCLPVLNTLQMAHNHLeTVEDIQHLQECLRLCVLDLSHNKLSDpEILSILESMPDLRVL 250
Cdd:PLN00113 475 KRLENLDLSRNQFSGAvpRKLGSLSELMQLKLSENKL-SGEIPDELSSCKKLVSLDLSHNQLSG-QIPASFSEMPVLSQL 552
|
90 100
....*....|....*....|....*...
gi 2462547415 251 NLMGNPVIRQIP----NYRRTVTVRLKH 274
Cdd:PLN00113 553 DLSQNQLSGEIPknlgNVESLVQVNISH 580
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
296-508 |
8.03e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 42.27 E-value: 8.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 296 RGGYAAEKEERQQWESRERK-KITDSIEALAMIKQRAEERKRQRESQERGmrsAEDNSPRVPLRLGEMTSSDDGENvpas 374
Cdd:PHA03169 26 HGGTREQAGRRRGTAARAAKpAPPAPTTSGPQVRAVAEQGHRQTESDTET---AEESRHGEKEERGQGGPSGSGSE---- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 375 aEGKEEPPGDRETRQkmELFVKESFEAKEELCPEKPSGEEPPvEAKREDGGP----EPEGTLPAETLLLSSPVEVKGEDG 450
Cdd:PHA03169 99 -SVGSPTPSPSGSAE--ELASGLSPENTSGSSPESPASHSPP-PSPPSHPGPhepaPPESHNPSPNQQPSSFLQPSHEDS 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2462547415 451 DGEPEGtlPAEAPPPPPPVEVKGEDGDQEPEGTLPAETlllsppvkvKGEDGDREPEG 508
Cdd:PHA03169 175 PEEPEP--PTSEPEPDSPGPPQSETPTSSPPPQSPPDE---------PGEPQSPTPQQ 221
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
302-508 |
1.19e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 41.88 E-value: 1.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 302 EKEERQQWESRERKKITDSIEALAMIKQRAEERKRQ--------RESQERGMRSAEDNSPRVPLRLGEMTSSDDGENVPA 373
Cdd:PHA03169 53 TSGPQVRAVAEQGHRQTESDTETAEESRHGEKEERGqggpsgsgSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPA 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 374 SAEGKEEPPGDRETRQKMElfvKESFEAKEELCPE---KPSGEEPPVEAKREDGGPEPEGTLPAET-LLLSSPVEVKGED 449
Cdd:PHA03169 133 SHSPPPSPPSHPGPHEPAP---PESHNPSPNQQPSsflQPSHEDSPEEPEPPTSEPEPDSPGPPQSeTPTSSPPPQSPPD 209
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2462547415 450 GDGEPEGTLPAEAPPPPPPVEVKGEDGDQEPEGTLPAETLLLSPPVKVKGEDGDREPEG 508
Cdd:PHA03169 210 EPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGPPFPGHRSHSYTVVGWKPSTRPGG 268
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
173-279 |
1.97e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 40.93 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 173 QKLDALNLSNNYIKTI------ENLSCLPVLNTLQMAHNHL---ETVEDIQHLQECLRLCVLDLSHNKLSDPEILSILES 243
Cdd:COG5238 180 NSVETVYLGCNQIGDEgieelaEALTQNTTVTTLWLKRNPIgdeGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEA 259
|
90 100 110
....*....|....*....|....*....|....*....
gi 2462547415 244 MPD---LRVLNLMGNPVIRQIPNYRRTVTVRLKHLTYLD 279
Cdd:COG5238 260 LKNnttVETLYLSGNQIGAEGAIALAKALQGNTTLTSLD 298
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
122-275 |
2.41e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 40.93 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 122 IENLEEYTGLRCLWLQSNGIQK------IENLEAQTELRCLFLQMNLLRK------IENLEPLQKLDALNLSNNYIKT-- 187
Cdd:COG5238 257 AEALKNNTTVETLYLSGNQIGAegaialAKALQGNTTLTSLDLSVNRIGDegaialAEGLQGNKTLHTLNLAYNGIGAqg 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547415 188 ----IENLSCLPVLNTLQMAHNHL--ETVEDI-QHLQECLRLCVLDLSHNKLSDPEILSILESM--PDLRVLNLMGNPVI 258
Cdd:COG5238 337 aialAKALQENTTLHSLDLSDNQIgdEGAIALaKYLEGNTTLRELNLGKNNIGKQGAEALIDALqtNRLHTLILDGNLIG 416
|
170
....*....|....*..
gi 2462547415 259 RQIpnyRRTVTVRLKHL 275
Cdd:COG5238 417 AEA---QQRLEQLLERI 430
|
|
|