|
Name |
Accession |
Description |
Interval |
E-value |
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
1-992 |
0e+00 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 1361.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 1 MGKLIRMGPQERWLLRTKRLHWSRLLFLLGMLIIGSTYQHLRRPRGLSSLWAAVSSHQPIKLASRDLSSEEMMMMSSSPS 80
Cdd:TIGR00927 1 MGKLIRMGTQERRLLRPKRLHWSRLLFLLGMLIIGSTYQHLRRPQGLPSLWAAVSSQQPIKLASRDLSNDEMMMVSSDPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 81 KPSSEMGGKMLVPQASVGSDEATLSMTVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTS-SRTLTYYTSTSS 159
Cdd:TIGR00927 81 KSSSEMEGEMLAPQATVGRDEATPSIAMENTPSPPRRTAKITPTTPKNNYSPTAAGTERVKEDTPATpSRALNHYISTSG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 160 RQIVKKYTPTPRGEMKSYSPTQVREKV-KYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKILETNSLK 238
Cdd:TIGR00927 161 RQRVKSYTPKPRGEVKSSSPTQTREKVrKYTPSPLGRMVNSYAPSTFMTMPRSHGITPRTTVKDSEITATYKMLETNPSK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 239 RIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPRRVESNSSAHPWGLVGKSNPKTPQGTVLLHTPAT 318
Cdd:TIGR00927 241 RTAGKTTPTPLKGMTDNTPTFLTREVETDLLTSPRSVVEKNTLTTPRRVESNSSTNHWGLVGKNNLTTPQGTVLEHTPAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 319 SEGQVTISTMTGSSPAETKAFTAAWSLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVK 398
Cdd:TIGR00927 321 SEGQVTISIMTGSSPAETKASTAAWKIRNPLSRTSAPAVRIASATFRGLEKNPSTAPSTPATPRVRAVLTTQVHHCVVVK 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 399 PTPAMLTTPSPSLTTALLPEELSPSPSVLPPSLPDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFV 478
Cdd:TIGR00927 401 PAPAVPTTPSPSLTTALFPEAPSPSPSALPPGQPDLHPKAEYPPDLFSVEERRQGWVVLHIFGMMYVFVALAIVCDEYFV 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 479 PALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPL 558
Cdd:TIGR00927 481 PALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 559 FRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVKEQLSRRPVAKVMALEDLSKpgdgaiav 638
Cdd:TIGR00927 561 FRDVSFYILDLMMLILFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIELWVKEQLSRRPVAKVMALGDLSK-------- 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 639 delqdnkklklpslltrgssstslhnstirstiyqlmlhsldplrevrlakekeeeslnqGARAQPQAKAESKPEEEEPA 718
Cdd:TIGR00927 633 ------------------------------------------------------------GDVAEAEHTGERTGEEGERP 652
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 719 klpavTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPG---------------EEGETAGEGETEEKSGGETQPEG-- 781
Cdd:TIGR00927 653 -----TEAEGENGEESGGEAEQEGETETKGENESEGEIPAerkgeqegegeieakEADHKGETEAEEVEHEGETEAEGte 727
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 782 -EGETETQGKGEE--------CEDENEAEGKGDN--------------EGEDEGEIHA-EDGEMKGNEG----------- 826
Cdd:TIGR00927 728 dEGEIETGEEGEEvedegegeAEGKHEVETEGDRketehegeteaegkEDEDEGEIQAgEDGEMKGDEGaegkveheget 807
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 827 -----------------------ETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEE 883
Cdd:TIGR00927 808 eagekdehegqsetqaddtevkdETGEQELNAENQGEAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEE 887
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 884 EEeeeeekgNEEPLSLDWPETRQKQAIYLFLLPIVFPLWLTVPDVRR------------------------------QVG 933
Cdd:TIGR00927 888 EE-------NEEPLSLEWPETRQKQAIYLFLLPIVFPLWLTVPDVRRqearkffvitflgsimwiamfsylmvwwahQVG 960
|
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462546698 934 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGV---WLLL 992
Cdd:TIGR00927 961 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLpvpWLLF 1022
|
|
| Na_Ca_ex |
pfam01699 |
Sodium/calcium exchanger protein; This is a family of sodium/calcium exchanger integral ... |
458-602 |
2.66e-32 |
|
Sodium/calcium exchanger protein; This is a family of sodium/calcium exchanger integral membrane proteins. This family covers the integral membrane regions of the proteins. Sodium/calcium exchangers regulate intracellular Ca2+ concentrations in many cells; cardiac myocytes, epithelial cells, neurons retinal rod photoreceptors and smooth muscle cells. Ca2+ is moved into or out of the cytosol depending on Na+ concentration. In humans and rats there are 3 isoforms; NCX1 NCX2 and NCX3.
Pssm-ID: 426387 [Multi-domain] Cd Length: 149 Bit Score: 122.71 E-value: 2.66e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 458 HVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNIL 537
Cdd:pfam01699 1 LSLLLFILGLLLISVAADLLVDSAEVLARVLGISGTVLGLTILALGTSLPELVSSIIAALRGEPDLALGNVIGSNIFNIL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 538 FVIGTCSLFS-----REILNLTwWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKW 602
Cdd:pfam01699 81 LVLGLSALIGpvkvdSLLLKLD-LGVLLLVALLLLLLLLLLLLPLFGRLSRFEGLVLLLLYIVYLVFQIV 149
|
|
| ECM27 |
COG0530 |
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; |
475-600 |
9.78e-25 |
|
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 440296 [Multi-domain] Cd Length: 293 Bit Score: 105.60 E-value: 9.78e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 475 EYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSReiLNLT 554
Cdd:COG0530 2 DLLVRGADALARRLGISPLVIGLTIVAFGTSLPELAVSVTAALDGSPDIAVGNVVGSNIANILLILGLAALIRP--LAVD 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2462546698 555 WWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTM 600
Cdd:COG0530 80 RRVLRRDLPFLLLASLLLLALLLDGTLSRIDGVILLLLYVLYLYYL 125
|
|
| PRK10734 |
PRK10734 |
putative calcium/sodium:proton antiporter; Provisional |
937-1004 |
2.85e-13 |
|
putative calcium/sodium:proton antiporter; Provisional
Pssm-ID: 182684 [Multi-domain] Cd Length: 325 Bit Score: 71.99 E-value: 2.85e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462546698 937 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITvgVWLLLPRLVCNGVISAH 1004
Cdd:PRK10734 205 AISELTIGLTVIAIGTSLPELATAIAGARKGENDIAVGNIIGSNIFNIV--IVLGLPALISPGEINPL 270
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
1-992 |
0e+00 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 1361.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 1 MGKLIRMGPQERWLLRTKRLHWSRLLFLLGMLIIGSTYQHLRRPRGLSSLWAAVSSHQPIKLASRDLSSEEMMMMSSSPS 80
Cdd:TIGR00927 1 MGKLIRMGTQERRLLRPKRLHWSRLLFLLGMLIIGSTYQHLRRPQGLPSLWAAVSSQQPIKLASRDLSNDEMMMVSSDPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 81 KPSSEMGGKMLVPQASVGSDEATLSMTVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTS-SRTLTYYTSTSS 159
Cdd:TIGR00927 81 KSSSEMEGEMLAPQATVGRDEATPSIAMENTPSPPRRTAKITPTTPKNNYSPTAAGTERVKEDTPATpSRALNHYISTSG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 160 RQIVKKYTPTPRGEMKSYSPTQVREKV-KYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKILETNSLK 238
Cdd:TIGR00927 161 RQRVKSYTPKPRGEVKSSSPTQTREKVrKYTPSPLGRMVNSYAPSTFMTMPRSHGITPRTTVKDSEITATYKMLETNPSK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 239 RIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPRRVESNSSAHPWGLVGKSNPKTPQGTVLLHTPAT 318
Cdd:TIGR00927 241 RTAGKTTPTPLKGMTDNTPTFLTREVETDLLTSPRSVVEKNTLTTPRRVESNSSTNHWGLVGKNNLTTPQGTVLEHTPAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 319 SEGQVTISTMTGSSPAETKAFTAAWSLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVK 398
Cdd:TIGR00927 321 SEGQVTISIMTGSSPAETKASTAAWKIRNPLSRTSAPAVRIASATFRGLEKNPSTAPSTPATPRVRAVLTTQVHHCVVVK 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 399 PTPAMLTTPSPSLTTALLPEELSPSPSVLPPSLPDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFV 478
Cdd:TIGR00927 401 PAPAVPTTPSPSLTTALFPEAPSPSPSALPPGQPDLHPKAEYPPDLFSVEERRQGWVVLHIFGMMYVFVALAIVCDEYFV 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 479 PALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPL 558
Cdd:TIGR00927 481 PALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 559 FRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVKEQLSRRPVAKVMALEDLSKpgdgaiav 638
Cdd:TIGR00927 561 FRDVSFYILDLMMLILFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIELWVKEQLSRRPVAKVMALGDLSK-------- 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 639 delqdnkklklpslltrgssstslhnstirstiyqlmlhsldplrevrlakekeeeslnqGARAQPQAKAESKPEEEEPA 718
Cdd:TIGR00927 633 ------------------------------------------------------------GDVAEAEHTGERTGEEGERP 652
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 719 klpavTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPG---------------EEGETAGEGETEEKSGGETQPEG-- 781
Cdd:TIGR00927 653 -----TEAEGENGEESGGEAEQEGETETKGENESEGEIPAerkgeqegegeieakEADHKGETEAEEVEHEGETEAEGte 727
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 782 -EGETETQGKGEE--------CEDENEAEGKGDN--------------EGEDEGEIHA-EDGEMKGNEG----------- 826
Cdd:TIGR00927 728 dEGEIETGEEGEEvedegegeAEGKHEVETEGDRketehegeteaegkEDEDEGEIQAgEDGEMKGDEGaegkveheget 807
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 827 -----------------------ETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEE 883
Cdd:TIGR00927 808 eagekdehegqsetqaddtevkdETGEQELNAENQGEAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEE 887
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 884 EEeeeeekgNEEPLSLDWPETRQKQAIYLFLLPIVFPLWLTVPDVRR------------------------------QVG 933
Cdd:TIGR00927 888 EE-------NEEPLSLEWPETRQKQAIYLFLLPIVFPLWLTVPDVRRqearkffvitflgsimwiamfsylmvwwahQVG 960
|
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462546698 934 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGV---WLLL 992
Cdd:TIGR00927 961 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLpvpWLLF 1022
|
|
| TIGR00367 |
TIGR00367 |
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and ... |
457-611 |
2.77e-45 |
|
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and archaeal proteins that is homologous, except for lacking a central region of ~ 250 amino acids and an N-terminal region of > 100 residues, to a functionally proven potassium-dependent sodium-calcium exchanger of the rat. [Unknown function, General]
Pssm-ID: 273039 [Multi-domain] Cd Length: 307 Bit Score: 165.57 E-value: 2.77e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 457 LHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNI 536
Cdd:TIGR00367 1 LLLIGYLILGLILLIYGADLFVKSSVRIARHLGISPLIIGVTVVAIGTSLPELFTSLIASLMGQPDIGVGNVIGSNIFNI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462546698 537 LFVIGTCSLFSrEILNLTWWpLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYvftMKWNKHIEVWVK 611
Cdd:TIGR00367 81 LLILGLSAIFS-PIIVDKDW-LRRDILFYLLVSILLLFFGLDGQISRIDGVVLLILYIVY---LLFLVKNERWVK 150
|
|
| Na_Ca_ex |
pfam01699 |
Sodium/calcium exchanger protein; This is a family of sodium/calcium exchanger integral ... |
458-602 |
2.66e-32 |
|
Sodium/calcium exchanger protein; This is a family of sodium/calcium exchanger integral membrane proteins. This family covers the integral membrane regions of the proteins. Sodium/calcium exchangers regulate intracellular Ca2+ concentrations in many cells; cardiac myocytes, epithelial cells, neurons retinal rod photoreceptors and smooth muscle cells. Ca2+ is moved into or out of the cytosol depending on Na+ concentration. In humans and rats there are 3 isoforms; NCX1 NCX2 and NCX3.
Pssm-ID: 426387 [Multi-domain] Cd Length: 149 Bit Score: 122.71 E-value: 2.66e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 458 HVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNIL 537
Cdd:pfam01699 1 LSLLLFILGLLLISVAADLLVDSAEVLARVLGISGTVLGLTILALGTSLPELVSSIIAALRGEPDLALGNVIGSNIFNIL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 538 FVIGTCSLFS-----REILNLTwWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKW 602
Cdd:pfam01699 81 LVLGLSALIGpvkvdSLLLKLD-LGVLLLVALLLLLLLLLLLLPLFGRLSRFEGLVLLLLYIVYLVFQIV 149
|
|
| TIGR00367 |
TIGR00367 |
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and ... |
905-996 |
4.41e-26 |
|
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and archaeal proteins that is homologous, except for lacking a central region of ~ 250 amino acids and an N-terminal region of > 100 residues, to a functionally proven potassium-dependent sodium-calcium exchanger of the rat. [Unknown function, General]
Pssm-ID: 273039 [Multi-domain] Cd Length: 307 Bit Score: 109.72 E-value: 4.41e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 905 RQKQAIYLFLLPIVFPLWLTVP-----DVRRQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGS 979
Cdd:TIGR00367 164 RRPQIFFSLVLLIIGLIGLVVGsrllvDGAVKIAEILGISEKIIGLTLLAIGTSLPELVVSLAAARKGLGDIAVGNVIGS 243
|
90 100
....*....|....*....|
gi 2462546698 980 NIFDITVGV---WLLLPRLV 996
Cdd:TIGR00367 244 NIFNILVGLgvpSLFMPIPV 263
|
|
| ECM27 |
COG0530 |
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; |
475-600 |
9.78e-25 |
|
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 440296 [Multi-domain] Cd Length: 293 Bit Score: 105.60 E-value: 9.78e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 475 EYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSReiLNLT 554
Cdd:COG0530 2 DLLVRGADALARRLGISPLVIGLTIVAFGTSLPELAVSVTAALDGSPDIAVGNVVGSNIANILLILGLAALIRP--LAVD 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2462546698 555 WWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTM 600
Cdd:COG0530 80 RRVLRRDLPFLLLASLLLLALLLDGTLSRIDGVILLLLYVLYLYYL 125
|
|
| Na_Ca_ex |
pfam01699 |
Sodium/calcium exchanger protein; This is a family of sodium/calcium exchanger integral ... |
931-996 |
3.44e-18 |
|
Sodium/calcium exchanger protein; This is a family of sodium/calcium exchanger integral membrane proteins. This family covers the integral membrane regions of the proteins. Sodium/calcium exchangers regulate intracellular Ca2+ concentrations in many cells; cardiac myocytes, epithelial cells, neurons retinal rod photoreceptors and smooth muscle cells. Ca2+ is moved into or out of the cytosol depending on Na+ concentration. In humans and rats there are 3 isoforms; NCX1 NCX2 and NCX3.
Pssm-ID: 426387 [Multi-domain] Cd Length: 149 Bit Score: 82.27 E-value: 3.44e-18
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462546698 931 QVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGV---WLLLPRLV 996
Cdd:pfam01699 26 VLARVLGISGTVLGLTILALGTSLPELVSSIIAALRGEPDLALGNVIGSNIFNILLVLglsALIGPVKV 94
|
|
| ECM27 |
COG0530 |
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; |
462-600 |
6.00e-18 |
|
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 440296 [Multi-domain] Cd Length: 293 Bit Score: 85.57 E-value: 6.00e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 462 MMYVFVALA--IVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFV 539
Cdd:COG0530 154 LLLLVLGLAllVVGARLLVDGAVEIARALGVSELVIGLTIVAIGTSLPELATSIVAARKGEDDLAVGNIIGSNIFNILLV 233
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462546698 540 IGTCSLFSReiLNLTWWPLFRDVSFYILDLIMLILFFL-DSLIAWWESLLLLLAYAFYVFTM 600
Cdd:COG0530 234 LGIGALITP--IPVDPAVLSFDLPVMLAATLLLLGLLRtGGRIGRWEGLLLLALYLAYLALL 293
|
|
| ECM27 |
COG0530 |
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; |
931-986 |
1.73e-17 |
|
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 440296 [Multi-domain] Cd Length: 293 Bit Score: 84.03 E-value: 1.73e-17
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2462546698 931 QVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITV 986
Cdd:COG0530 177 EIARALGVSELVIGLTIVAIGTSLPELATSIVAARKGEDDLAVGNIIGSNIFNILL 232
|
|
| PRK10734 |
PRK10734 |
putative calcium/sodium:proton antiporter; Provisional |
937-1004 |
2.85e-13 |
|
putative calcium/sodium:proton antiporter; Provisional
Pssm-ID: 182684 [Multi-domain] Cd Length: 325 Bit Score: 71.99 E-value: 2.85e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462546698 937 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITvgVWLLLPRLVCNGVISAH 1004
Cdd:PRK10734 205 AISELTIGLTVIAIGTSLPELATAIAGARKGENDIAVGNIIGSNIFNIV--IVLGLPALISPGEINPL 270
|
|
| TIGR00367 |
TIGR00367 |
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and ... |
465-586 |
6.73e-13 |
|
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and archaeal proteins that is homologous, except for lacking a central region of ~ 250 amino acids and an N-terminal region of > 100 residues, to a functionally proven potassium-dependent sodium-calcium exchanger of the rat. [Unknown function, General]
Pssm-ID: 273039 [Multi-domain] Cd Length: 307 Bit Score: 70.82 E-value: 6.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 465 VFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCS 544
Cdd:TIGR00367 177 IGLIGLVVGSRLLVDGAVKIAEILGISEKIIGLTLLAIGTSLPELVVSLAAARKGLGDIAVGNVIGSNIFNILVGLGVPS 256
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2462546698 545 LFSR-EILNLTwwpLFRDVSFYILDLIMLILFF-LDSLIAWWES 586
Cdd:TIGR00367 257 LFMPiPVEPLA---YNLDAPVMVIVTLLLMLFFkTSMKLGRWEG 297
|
|
| ECM27 |
COG0530 |
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; |
937-986 |
3.38e-11 |
|
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 440296 [Multi-domain] Cd Length: 293 Bit Score: 65.15 E-value: 3.38e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 2462546698 937 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITV 986
Cdd:COG0530 16 GISPLVIGLTIVAFGTSLPELAVSVTAALDGSPDIAVGNVVGSNIANILL 65
|
|
| TIGR00367 |
TIGR00367 |
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and ... |
910-984 |
6.05e-10 |
|
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and archaeal proteins that is homologous, except for lacking a central region of ~ 250 amino acids and an N-terminal region of > 100 residues, to a functionally proven potassium-dependent sodium-calcium exchanger of the rat. [Unknown function, General]
Pssm-ID: 273039 [Multi-domain] Cd Length: 307 Bit Score: 61.57 E-value: 6.05e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462546698 910 IYLFLLPIVFPLWLTVPDVRRqVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 984
Cdd:TIGR00367 7 LILGLILLIYGADLFVKSSVR-IARHLGISPLIIGVTVVAIGTSLPELFTSLIASLMGQPDIGVGNVIGSNIFNI 80
|
|
| caca |
TIGR00845 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
462-543 |
1.07e-09 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 62.50 E-value: 1.07e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 462 MMYVFVALAIVCDEyFVPALGVITDK-----------------LQI-SEDVAGATFMAAGGSAPELFTSLIGV----FIS 519
Cdd:TIGR00845 82 MVYMFLGVSIIADR-FMASIEVITSQekeitikkpngettvttVRIwNETVSNLTLMALGSSAPEILLSVIEVcghnFEA 160
|
90 100
....*....|....*....|....
gi 2462546698 520 hSNVGIGTIVGSAVFNILFVIGTC 543
Cdd:TIGR00845 161 -GDLGPSTIVGSAAFNMFIIIAIC 183
|
|
| PRK10734 |
PRK10734 |
putative calcium/sodium:proton antiporter; Provisional |
483-547 |
1.23e-07 |
|
putative calcium/sodium:proton antiporter; Provisional
Pssm-ID: 182684 [Multi-domain] Cd Length: 325 Bit Score: 54.65 E-value: 1.23e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462546698 483 VITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFS 547
Cdd:PRK10734 199 VLANYFAISELTIGLTVIAIGTSLPELATAIAGARKGENDIAVGNIIGSNIFNIVIVLGLPALIS 263
|
|
| PRK10734 |
PRK10734 |
putative calcium/sodium:proton antiporter; Provisional |
935-984 |
3.16e-07 |
|
putative calcium/sodium:proton antiporter; Provisional
Pssm-ID: 182684 [Multi-domain] Cd Length: 325 Bit Score: 53.50 E-value: 3.16e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 2462546698 935 TIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 984
Cdd:PRK10734 32 TFGIPPLIIGMTVVGIGTSLPEIIVSVAASLHGQRDLAVGTALGSNITNI 81
|
|
| PLN03151 |
PLN03151 |
cation/calcium exchanger; Provisional |
453-605 |
1.07e-06 |
|
cation/calcium exchanger; Provisional
Pssm-ID: 215604 [Multi-domain] Cd Length: 650 Bit Score: 52.84 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 453 GWVVLHVFgMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSlIGVFISHS--NVGIGTIVG 530
Cdd:PLN03151 139 GYAVLGVW-LVALFYLLGNTAADYFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAPDVFAS-IAAFVGKDagEVGLNSVLG 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 531 SAVFNILFVIGTCSL-FSREILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWN----KH 605
Cdd:PLN03151 217 GAVFVTCVVVGIVSLcVADKEVQIDKRCFIRDLCFFLFTLVSLLVILMVGKVTVGGAIAFVSIYVVYAFLVAANeilrKH 296
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
103-360 |
6.67e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 40.67 E-value: 6.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 103 TLSMTVENIPSMPK-----RTAKMIPTTT----------KNNYSPTAAGTERRKEDT----PTSSRTLTYYTSTSSR--- 160
Cdd:pfam05109 388 TFDITVSGLGTAPKtliitRTATNATTTThkvifskapeSTTTSPTLNTTGFAAPNTttglPSSTHVPTNLTAPASTgpt 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 161 -QIVKKYTPTPRGEMKSYSPTqvrekvkyTPSPRGRRVGTYVPSTFMTMETSHAITPrtTVKDSDITATYKILETNSLKR 239
Cdd:pfam05109 468 vSTADVTSPTPAGTTSGASPV--------TPSPSPRDNGTESKAPDMTSPTSAVTTP--TPNATSPTPAVTTPTPNATSP 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 240 IMEETTPTTLKgmfdSTPTfltheveanvltsprsvmeKNNLFPPRRVESNSSAHPWGLVGKSNPKTpqgTVLLHTPATS 319
Cdd:pfam05109 538 TLGKTSPTSAV----TTPT-------------------PNATSPTPAVTTPTPNATIPTLGKTSPTS---AVTTPTPNAT 591
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2462546698 320 EGQVTISTMTGSSPAETKAFTAAWSLRNPSPRTSVSAIKTA 360
Cdd:pfam05109 592 SPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTG 632
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
490-582 |
6.92e-03 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 40.36 E-value: 6.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462546698 490 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPLFRDVSFYILDL 569
Cdd:TIGR00927 965 ISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVSSNGLFCAIVL 1044
|
90
....*....|...
gi 2462546698 570 IMLILFFLDSLIA 582
Cdd:TIGR00927 1045 LFLMLLFVISSIA 1057
|
|
| |
