NCBI Conserved Domain Search

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1150-1635

1.76e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 95.77 E-value: 1.76e-19

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1150 EQLSEAALKAMEEAVAQV--LEQDQRHLLESKQEKMQQLREKlcQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARM 1227
Cdd:COG1196    280 ELELEEAQAEEYELLAELarLEQDIARLEERRRELEERLEEL--EEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1228 REEESQRLSwlRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM-LEQLKEEIEASEKSEQAALN 1306
Cdd:COG1196    358 AELAEAEEA--LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErLERLEEELEELEEALAELEE 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1307 AAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ--------------L 1372
Cdd:COG1196    436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEadyegflegvkaalL 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1373 QKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEH-QQVMAKAREQYEAEERKQRAELLGHLTG 1451
Cdd:COG1196    516 LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLkAAKAGRATFLPLDKIRARAALAAALARG 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1452 ELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQV 1531
Cdd:COG1196    596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1532 ALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQsqqlqkhfssLEAEAQKKQHLLREV 1611
Cdd:COG1196    676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL----------EAEREELLEELLEEE 745

                          490       500
                   ....*....|....*....|....
gi 2462523724 1612 TVEENNASPHFEPDLHIEDLRKSL 1635
Cdd:COG1196    746 ELLEEEALEELPEPPDLEELEREL 769

PTZ00121

MAEBL; Provisional

1000-1610

1.31e-18

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 93.67 E-value: 1.31e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1000 RQAQQPLGIED-KDDSQSSQDELQSKQSKglEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPE---GQPEWKEAEEL 1075
Cdd:PTZ00121  1218 RKAEDAKKAEAvKKAEEAKKDAEEAKKAE--EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADelkKAEEKKKADEA 1295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1076 GEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEkvavsptppvspeVRSTEPVAPPEQLSEA 1155
Cdd:PTZ00121  1296 KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAE-------------AAKAEAEAAADEAEAA 1362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1156 ALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKlcqeeeeeilrlhQQKEQSLSSLRERLQKAieeeearmrEEESQRL 1235
Cdd:PTZ00121  1363 EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA-------------KKKAEEDKKKADELKKA---------AAAKKKA 1420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1236 SWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNA--AKEKAl 1313
Cdd:PTZ00121  1421 DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAeeAKKKA- 1499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1314 QQLREQLEgERKEAVATLEKEHSAELERLCSSLEAKHREVVsslqKKIQEAQQKEEAQLQKCLGQVEHRvhQKSYHVAGY 1393
Cdd:PTZ00121  1500 DEAKKAAE-AKKKADEAKKAEEAKKADEAKKAEEAKKADEA----KKAEEKKKADELKKAEELKKAEEK--KKAEEAKKA 1572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1394 EHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQ-EQH 1472
Cdd:PTZ00121  1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKaEEL 1652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1473 KRLEDLRRRHREQERKlqdleldletRAKDVKARLALLEVQEETARREKQQLLDvqrqvalKSEEAtathQQLEEAQKEH 1552
Cdd:PTZ00121  1653 KKAEEENKIKAAEEAK----------KAEEDKKKAEEAKKAEEDEKKAAEALKK-------EAEEA----KKAEELKKKE 1711

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462523724 1553 THLLQSNQQLREildELQARKLKLEsQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLRE 1610
Cdd:PTZ00121  1712 AEEKKKAEELKK---AEEENKIKAE-EAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKE 1765

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1170-1765

3.24e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 85.49 E-value: 3.24e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1170 QDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQAD 1249
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEK-LEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1250 E-DQIRaEQEASLQKLREELESQQKAERASLEqKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEgeRKEAV 1328
Cdd:TIGR02168  387 KvAQLE-LQIASLNNEIERLEARLERLEDRRE-RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE--RLEEA 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1329 ATLEKEHSAELERLCSSLEAKHREVVSslQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV----------AGYEHELS 1398
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQA--RLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvdEGYEAAIE 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1399 SLLREKRQEVEGEHE----------------------------------RRLDKMKEEHQQVMAKAREQYEAEERKQRAE 1444
Cdd:TIGR02168  541 AALGGRLQAVVVENLnaakkaiaflkqnelgrvtflpldsikgteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKALSY 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1445 LLGH------LTGELERLQRAHEREL----------------------ETVRQEQHKRLEDLRRRHREQERKLQDLEL-- 1494
Cdd:TIGR02168  621 LLGGvlvvddLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKal 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1495 -DLETRAKDVKARLALLEVQEETARRE----KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDEL 1569
Cdd:TIGR02168  701 aELRKELEELEEELEQLRKELEELSRQisalRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1570 QARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQK-KQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLS 1648
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAELTLlNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1649 QSKEDLYLDSLSSHNVWHL-----LSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVakdppgIKAL 1723
Cdd:TIGR02168  861 IEELEELIEELESELEALLnerasLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR------LEGL 934

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 2462523724 1724 EDMRKNL-----EKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSL 1765
Cdd:TIGR02168  935 EVRIDNLqerlsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

1256-1573

1.11e-14

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 79.78 E-value: 1.11e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1256 EQEASLQKLREELESQQKAERASLEQKNRQMLE-----QLKEEIEASEKSEQAALNAAKEKALQQLREQ-----LEGERK 1325
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEaekarQAEMDRQAAIYAEQERMAMERERELERIRQEerkreLERIRQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1326 EAVAtLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQlqkclgqveHRVHQKSYHVAGYEHELSSLLREKR 1405
Cdd:pfam17380  368 EEIA-MEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQ---------RKIQQQKVEMEQIRAEQEEARQREV 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1406 QEVEGEHERRLDKMKEEH---QQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQHKRLEDLRRRH 1482
Cdd:pfam17380  438 RRLEEERAREMERVRLEEqerQQQVERLRQQEEERKRKKL---------ELEKEKRDRKRAEEQRRKILEKELEERKQAM 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1483 REQERKLQDLELDLETRAKDVKARLALLEVQEEtarREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHthllqsnQQL 1562
Cdd:pfam17380  509 IEEERKRKLLEKEMEERQKAIYEEERRREAEEE---RRKQQEMEERRRIQEQMRKATEERSRLEAMERER-------EMM 578

                          330
                   ....*....|.
gi 2462523724 1563 REILDELQARK 1573
Cdd:pfam17380  579 RQIVESEKARA 589

cd00201

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ...

59-89

7.01e-06

Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 44.44 E-value: 7.01e-06

                           10        20        30
                   ....*....|....*....|....*....|.
gi 2462523724   59 PGEWKPCQDITGDIYYFNFANGQSMWDHPCD 89
Cdd:cd00201      1 PPGWEERWDPDGRVYYYNHNTKETQWEDPRE 31

pfam00397

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ...

58-87

1.73e-05

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro.

Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 43.26 E-value: 1.73e-05

                           10        20        30
                   ....*....|....*....|....*....|
gi 2462523724   58 LPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:pfam00397    1 LPPGWEERWDPDGRVYYYNHETGETQWEKP 30

smart00456

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...

57-87

4.29e-05

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.

Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 42.20 E-value: 4.29e-05

                            10        20        30
                    ....*....|....*....|....*....|.
gi 2462523724    57 PLPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:smart00456    1 PLPPGWEERKDPDGRPYYYNHETKETQWEKP 31

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

1251-1444

7.57e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 48.29 E-value: 7.57e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1251 DQIRAEQEASLQ--KLREELESQQKAERASLEQK----NRQMLEQLKEEIEASEKSEQAALNAAKEKAL----QQLREQL 1320
Cdd:NF012221  1532 DNVVATSESSQQadAVSKHAKQDDAAQNALADKEraeaDRQRLEQEKQQQLAAISGSQSQLESTDQNALetngQAQRDAI 1611

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1321 EGERKEAVATLEK------------EHSAEL---------ERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgQV 1379
Cdd:NF012221  1612 LEESRAVTKELTTlaqgldaldsqaTYAGESgdqwrnpfaGGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQ----KV 1687

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462523724 1380 EHRVHQKSYHVA-GYEHELSSLLREKRQEVEGEhERRLDKMKEEHQQVMAKAREQYEAEERKQRAE 1444
Cdd:NF012221  1688 KDAVAKSEAGVAqGEQNQANAEQDIDDAKADAE-KRKDDALAKQNEAQQAESDANAAANDAQSRGE 1752

PHA03307

transcriptional regulator ICP4; Provisional

823-1173

1.59e-04

transcriptional regulator ICP4; Provisional

Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.09 E-value: 1.59e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  823 SQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAvgkgRQGSGARPGLPEKEENEKSEPKicRNLVTPKADPTGSEPA 902
Cdd:PHA03307    45 SDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAP----ANESRSTPTWSLSTLAPASPAR--EGSPTPPGPSSPDPPP 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  903 KASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEleiSEHMKEPQLSDSIASDPKSFHGL-----DFGF 977
Cdd:PHA03307   119 PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVA---SDAASSRQAALPLSSPEETARAPssppaEPPP 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  978 RSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERyHRLSPPLPHEERAQSPPRSLATEE 1057
Cdd:PHA03307   196 STPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWG-PENECPLPRPAPITLPTRIWEASG 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1058 EPPQGPEGQPEWKEAEELGEDSAAS--------LSLQLSLQREQAPSPPAACEKGKEQHSQAEELG--PGQEEAEDPEEK 1127
Cdd:PHA03307   275 WNGPSSRPGPASSSSSPRERSPSPSpsspgsgpAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAvsPGPSPSRSPSPS 354

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 2462523724 1128 VAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQR 1173
Cdd:PHA03307   355 RPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARR 400

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

1357-1528

2.08e-04

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 45.65 E-value: 2.08e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1357 LQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV-AGY------------------------EHELSSLLREKrqEVEGE 1411
Cdd:cd16269    107 CKQNEEASSKRCQALLQELSAPLEEKISQGSYSVpGGYqlyledreklvekyrqvprkgvkaEEVLQEFLQSK--EAEAE 184

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1412 HERRLDKMKEEHQQVMAKAREQYEAEErkQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQD 1491
Cdd:cd16269    185 AILQADQALTEKEKEIEAERAKAEAAE--QERKLLEEQQRELEQKLEDQERSYEEHLRQLKEKMEEERENLLKEQERALE 262

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2462523724 1492 LELDLETRakdvkarlALLEVQEETARREKQQLLDVQ 1528
Cdd:cd16269    263 SKLKEQEA--------LLEEGFKEQAELLQEEIRSLK 291

OmpH

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

1262-1367

5.90e-04

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 42.19 E-value: 5.90e-04

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  1262 QKLREELESQQKAERASLEQKNRQmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKehsaeler 1341
Cdd:smart00935   17 KAAQKQLEKEFKKRQAELEKLEKE-LQKLKEKLQKDAATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQK-------- 87

                            90       100
                    ....*....|....*....|....*.
gi 2462523724  1342 lcssleaKHREVVSSLQKKIQEAQQK 1367
Cdd:smart00935   88 -------RQQEELQKILDKINKAIKE 106

growth_prot_Scy

NF041483

polarized growth protein Scy;

1232-1556

6.47e-03

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 41.74 E-value: 6.47e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1232 SQRLSWLRAQVQSSTQAdedQIRAEQEASLQKLREEL-ESQQKAE-------------RASLEQKNRQMLEQLKEEIEAS 1297
Cdd:NF041483   103 TQRILQEHAEHQARLQA---ELHTEAVQRRQQLDQELaERRQTVEshvnenvawaeqlRARTESQARRLLDESRAEAEQA 179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1298 EKSEQAALNAAKEKALQQLREQLEGERKEAVATLEK-----------------EHSAELERLCSSL-----EAKHR--EV 1353
Cdd:NF041483   180 LAAARAEAERLAEEARQRLGSEAESARAEAEAILRRarkdaerllnaastqaqEATDHAEQLRSSTaaesdQARRQaaEL 259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1354 VSSLQKKIQEAQQK---EEAQLQKCLGQVEHRVHQKsyhVAGYEHELSSLLREKRQEVE---GEHERRLDKMKEEHQQVM 1427
Cdd:NF041483   260 SRAAEQRMQEAEEAlreARAEAEKVVAEAKEAAAKQ---LASAESANEQRTRTAKEEIArlvGEATKEAEALKAEAEQAL 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1428 AKAREQYE-----AEERKQRA-----------------ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQ 1485
Cdd:NF041483   337 ADARAEAEklvaeAAEKARTVaaedtaaqlakaartaeEVLTKASEDAKATTRAAAEEAERIRREAEAEADRLRGEAADQ 416

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462523724 1486 ERKLQDLELD--LETRAKDVkarlallEVQEEtARR---EKQQLLD--VQRQVALKSEEATATHQQLEEAQKEHTHLL 1556
Cdd:NF041483   417 AEQLKGAAKDdtKEYRAKTV-------ELQEE-ARRlrgEAEQLRAeaVAEGERIRGEARREAVQQIEEAARTAEELL 486

Treacle

pfam03546

Treacher Collins syndrome protein Treacle;

823-1181

6.58e-03

Treacher Collins syndrome protein Treacle;

Pssm-ID: 460967 [Multi-domain] Cd Length: 531 Bit Score: 41.21 E-value: 6.58e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  823 SQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKGRQGSGARPGLPEK--------------EENEKSEPKICRN 888
Cdd:pfam03546   26 SSSEEESDSEEETPAAKTPLQAKPSGKTPQVRAASAPAKESPRKGAPPVPPGKtgpaaaqaqagkpeEDSESSSEESDSD 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  889 LVTPKADPTGSEPAKA--SEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQElEISEHMKEPQLSDSIASD 966
Cdd:pfam03546  106 GETPAAATLTTSPAQVkpLGKNSQVRPASTVGKGPSGKGANPAPPGKAGSAAPLVQVGKKE-EDSESSSEESDSEGEAPP 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  967 PKSfhgldfgfRSRISEHLLDVDVLSPVLGGACRQAQQPLGI--------EDKDDSQSSQDELQSKQSKGLEERYHRLSP 1038
Cdd:pfam03546  185 AAT--------QAKPSGKILQVRPASGPAKGAAPAPPQKAGPvatqvkaeRSKEDSESSEESSDSEEEAPAAATPAQAKP 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1039 PLPHEERAQSP----PRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEEL 1114
Cdd:pfam03546  257 ALKTPQTKASPrkgtPITPTSAKVPPVRVGTPAPWKAGTVTSPACASSPAVARGAQRPEEDSSSSEESESEEETAPAAAV 336

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462523724 1115 GPGQEEAEDPEEKVAVSPTPpvSPEVRSTEPVAPpeqlseaalKAMEEAVAQVLEQDQRHLLESKQE 1181
Cdd:pfam03546  337 GQAKSVGKGLQGKAASAPTK--GPSGQGTAPVPP---------GKTGPAVAQVKAEAQEDSESSEEE 392

Name

Accession

Description

Interval

E-value

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1150-1635

1.76e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 95.77 E-value: 1.76e-19

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1150 EQLSEAALKAMEEAVAQV--LEQDQRHLLESKQEKMQQLREKlcQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARM 1227
Cdd:COG1196    280 ELELEEAQAEEYELLAELarLEQDIARLEERRRELEERLEEL--EEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1228 REEESQRLSwlRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM-LEQLKEEIEASEKSEQAALN 1306
Cdd:COG1196    358 AELAEAEEA--LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErLERLEEELEELEEALAELEE 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1307 AAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ--------------L 1372
Cdd:COG1196    436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEadyegflegvkaalL 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1373 QKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEH-QQVMAKAREQYEAEERKQRAELLGHLTG 1451
Cdd:COG1196    516 LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLkAAKAGRATFLPLDKIRARAALAAALARG 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1452 ELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQV 1531
Cdd:COG1196    596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1532 ALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQsqqlqkhfssLEAEAQKKQHLLREV 1611
Cdd:COG1196    676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL----------EAEREELLEELLEEE 745

                          490       500
                   ....*....|....*....|....
gi 2462523724 1612 TVEENNASPHFEPDLHIEDLRKSL 1635
Cdd:COG1196    746 ELLEEEALEELPEPPDLEELEREL 769

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1200-1769

6.96e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 93.85 E-value: 6.96e-19

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1200 RLHQQKEQSLS--SLRERLQKAIEEEEARMREEESQRLSWLRAQVQSsTQADEDQIRAEQEAsLQKLREELESQQKAERA 1277
Cdd:COG1196    204 PLERQAEKAERyrELKEELKELEAELLLLKLRELEAELEELEAELEE-LEAELEELEAELAE-LEAELEELRLELEELEL 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1278 SLEQKNRQmLEQLKEEIEASEKseQAALNAAKEKALQQLREQLEGERKEAVATLEkEHSAELERLCSSLEAkhrevvssl 1357
Cdd:COG1196    282 ELEEAQAE-EYELLAELARLEQ--DIARLEERRRELEERLEELEEELAELEEELE-ELEEELEELEEELEE--------- 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1358 QKKIQEAQQKEEAQLQKclgqvehrvhqksyhvagyehELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAE 1437
Cdd:COG1196    349 AEEELEEAEAELAEAEE---------------------ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1438 ERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETA 1517
Cdd:COG1196    408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1518 RREKQQLLDvqrqvalksEEATATHQQLEEAQKEhTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSL 1597
Cdd:COG1196    488 EAAARLLLL---------LEAEADYEGFLEGVKA-ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1598 EAEAQ----KKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEvssslsqskEDLYLDSLSSHNVWHLLSAEGV 1673
Cdd:COG1196    558 VAAAAieylKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS---------DLREADARYYVLGDTLLGRTLV 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1674 ALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKK 1753
Cdd:COG1196    629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          570
                   ....*....|....*.
gi 2462523724 1754 KEEKLNQLESSLWEEA 1769
Cdd:COG1196    709 LAEAEEERLEEELEEE 724

PTZ00121

MAEBL; Provisional

1000-1610

1.31e-18

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 93.67 E-value: 1.31e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1000 RQAQQPLGIED-KDDSQSSQDELQSKQSKglEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPE---GQPEWKEAEEL 1075
Cdd:PTZ00121  1218 RKAEDAKKAEAvKKAEEAKKDAEEAKKAE--EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADelkKAEEKKKADEA 1295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1076 GEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEkvavsptppvspeVRSTEPVAPPEQLSEA 1155
Cdd:PTZ00121  1296 KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAE-------------AAKAEAEAAADEAEAA 1362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1156 ALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKlcqeeeeeilrlhQQKEQSLSSLRERLQKAieeeearmrEEESQRL 1235
Cdd:PTZ00121  1363 EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA-------------KKKAEEDKKKADELKKA---------AAAKKKA 1420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1236 SWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNA--AKEKAl 1313
Cdd:PTZ00121  1421 DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAeeAKKKA- 1499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1314 QQLREQLEgERKEAVATLEKEHSAELERLCSSLEAKHREVVsslqKKIQEAQQKEEAQLQKCLGQVEHRvhQKSYHVAGY 1393
Cdd:PTZ00121  1500 DEAKKAAE-AKKKADEAKKAEEAKKADEAKKAEEAKKADEA----KKAEEKKKADELKKAEELKKAEEK--KKAEEAKKA 1572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1394 EHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQ-EQH 1472
Cdd:PTZ00121  1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKaEEL 1652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1473 KRLEDLRRRHREQERKlqdleldletRAKDVKARLALLEVQEETARREKQQLLDvqrqvalKSEEAtathQQLEEAQKEH 1552
Cdd:PTZ00121  1653 KKAEEENKIKAAEEAK----------KAEEDKKKAEEAKKAEEDEKKAAEALKK-------EAEEA----KKAEELKKKE 1711

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462523724 1553 THLLQSNQQLREildELQARKLKLEsQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLRE 1610
Cdd:PTZ00121  1712 AEEKKKAEELKK---AEEENKIKAE-EAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKE 1765

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1154-1733

2.43e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 88.84 E-value: 2.43e-17

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1154 EAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQ 1233
Cdd:COG1196    228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1234 RLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLE--QKNRQMLEQLKEEIEASEKSEQAALNAAKEK 1311
Cdd:COG1196    308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEeaEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1312 ALQQLREQLEGERKEA-VATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV 1390
Cdd:COG1196    388 LLEALRAAAELAAQLEeLEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1391 AGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLtGELERLQRAHERELETVRQE 1470
Cdd:COG1196    468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV-AVLIGVEAAYEAALEAALAA 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1471 QhkrledLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEAtathqqLEEAQK 1550
Cdd:COG1196    547 A------LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL------READAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1551 EHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENnasphfepdlhIED 1630
Cdd:COG1196    615 YYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE-----------LEE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1631 LRKSLGTNQTKEVSSSLSQSKEDLyldslsshnvwHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASA 1710
Cdd:COG1196    684 LAERLAEEELELEEALLAEEEEER-----------ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                          570       580
                   ....*....|....*....|...
gi 2462523724 1711 QEVAKDPPGIKALEDMRKNLEKE 1733
Cdd:COG1196    753 LEELPEPPDLEELERELERLERE 775

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1151-1581

2.71e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 88.84 E-value: 2.71e-17

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1151 QLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKlcQEEEEEILRLhQQKEQSLSSLRERLQKAIEEEEARMREE 1230
Cdd:COG1196    357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA--AELAAQLEEL-EEAEEALLERLERLEEELEELEEALAEL 433

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1231 ESQRLSWLRAQVQ-SSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRqmLEQLKEEIEASEKSEQAALNAAK 1309
Cdd:COG1196    434 EEEEEEEEEALEEaAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLEGVK 511

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1310 EKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKC-LGQVEHRVHQKSY 1388
Cdd:COG1196    512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLpLDKIRARAALAAA 591

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1389 HVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEhqqVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVR 1468
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGR---TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1469 QEQHKRLEDLRRRhREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEAtatHQQLEEA 1548
Cdd:COG1196    669 ELLAALLEAEAEL-EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL---LEELLEE 744

                          410       420       430
                   ....*....|....*....|....*....|...
gi 2462523724 1549 QKEHTHLLQSNQQLREILDELQARKLKLESQVD 1581
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLEREIE 777

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1170-1765

3.24e-16

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 85.49 E-value: 3.24e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1170 QDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQAD 1249
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEK-LEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1250 E-DQIRaEQEASLQKLREELESQQKAERASLEqKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEgeRKEAV 1328
Cdd:TIGR02168  387 KvAQLE-LQIASLNNEIERLEARLERLEDRRE-RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE--RLEEA 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1329 ATLEKEHSAELERLCSSLEAKHREVVSslQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV----------AGYEHELS 1398
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQA--RLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvdEGYEAAIE 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1399 SLLREKRQEVEGEHE----------------------------------RRLDKMKEEHQQVMAKAREQYEAEERKQRAE 1444
Cdd:TIGR02168  541 AALGGRLQAVVVENLnaakkaiaflkqnelgrvtflpldsikgteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKALSY 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1445 LLGH------LTGELERLQRAHEREL----------------------ETVRQEQHKRLEDLRRRHREQERKLQDLEL-- 1494
Cdd:TIGR02168  621 LLGGvlvvddLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKal 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1495 -DLETRAKDVKARLALLEVQEETARRE----KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDEL 1569
Cdd:TIGR02168  701 aELRKELEELEEELEQLRKELEELSRQisalRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1570 QARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQK-KQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLS 1648
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAELTLlNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1649 QSKEDLYLDSLSSHNVWHL-----LSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVakdppgIKAL 1723
Cdd:TIGR02168  861 IEELEELIEELESELEALLnerasLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR------LEGL 934

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 2462523724 1724 EDMRKNL-----EKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSL 1765
Cdd:TIGR02168  935 EVRIDNLqerlsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1313-1611

4.37e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.60 E-value: 4.37e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1313 LQQLREQLEGERKEAVATLE-KEHSAELERLCSSLEAKHREVVSSLQKKIQ---EAQQKEEAQLQKCLGQVEHRVHQksy 1388
Cdd:COG1196    195 LGELERQLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEaelEELEAELEELEAELAELEAELEE--- 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1389 hvAGYEHELSSLLREKRQEVEGEHERRLDKM--KEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHE----- 1461
Cdd:COG1196    272 --LRLELEELELELEEAQAEEYELLAELARLeqDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEeleea 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1462 ----RELETVRQEQHKRLEDLRRRHREQERKLQDL---ELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALK 1534
Cdd:COG1196    350 eeelEEAEAELAEAEEALLEAEAELAEAEEELEELaeeLLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1535 SEEAT----ATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLRE 1610
Cdd:COG1196    430 LAELEeeeeEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509


                   .
gi 2462523724 1611 V 1611
Cdd:COG1196    510 V 510

PTZ00121

MAEBL; Provisional

1057-1768

7.50e-16

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 84.42 E-value: 7.50e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1057 EEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVsptppv 1136
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAE------ 1185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1137 spEVRSTEPVAPPEQL--SEAALKAMEEAVAqvlEQDQRHLLESKQEKMQQLREklcqeeeeeilrLHQQKEQSLSSLRE 1214
Cdd:PTZ00121  1186 --EVRKAEELRKAEDArkAEAARKAEEERKA---EEARKAEDAKKAEAVKKAEE------------AKKDAEEAKKAEEE 1248

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1215 RLQKAIEEEEARMREEESQRLSWLRAQvqSSTQADEDQiRAEQEASLQKLREElESQQKAERASLEQKNRQMLEQLKEEI 1294
Cdd:PTZ00121  1249 RNNEEIRKFEEARMAHFARRQAAIKAE--EARKADELK-KAEEKKKADEAKKA-EEKKKADEAKKKAEEAKKADEAKKKA 1324

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1295 EASEKSEQAALNAAKE--KALQQLREQLEGERKEAVATLEKEHSAELERLcsslEAKHRevVSSLQKKIQEAQQKEEAQl 1372
Cdd:PTZ00121  1325 EEAKKKADAAKKKAEEakKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE----EAKKK--ADAAKKKAEEKKKADEAK- 1397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1373 qkclgqvehrvhQKSYHVAGYEHELSSLLREKRQEVE----GEHERRLDKMKEehqqvmaKAREQYEAEERKQRAELLGH 1448
Cdd:PTZ00121  1398 ------------KKAEEDKKKADELKKAAAAKKKADEakkkAEEKKKADEAKK-------KAEEAKKADEAKKKAEEAKK 1458

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1449 LTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLAllevqeETARREKQqlldvq 1528
Cdd:PTZ00121  1459 AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA------EEAKKADE------ 1526

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1529 rqvALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQvdllqaqsqqlQKHFSSLEAEAQKKqhlL 1608
Cdd:PTZ00121  1527 ---AKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEE-----------DKNMALRKAEEAKK---A 1589

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1609 REVTVEENNASPHFEPDLHIEDLRKSlgtNQTKEVSSSLSQSKEDlyldslsSHNVWHLLSAEGVALRSAKEFL-VQQTR 1687
Cdd:PTZ00121  1590 EEARIEEVMKLYEEEKKMKAEEAKKA---EEAKIKAEELKKAEEE-------KKKVEQLKKKEAEEKKKAEELKkAEEEN 1659

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1688 SMRRRQTALKAAQQHWRHELA---------SAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA----MRKGHNLLKKK 1754
Cdd:PTZ00121  1660 KIKAAEEAKKAEEDKKKAEEAkkaeedekkAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAeeenKIKAEEAKKEA 1739

                          730
                   ....*....|....
gi 2462523724 1755 EEKLNQLESSLWEE 1768
Cdd:PTZ00121  1740 EEDKKKAEEAKKDE 1753

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1150-1740

1.63e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.06 E-value: 1.63e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1150 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEeilrlHQQKEQSLSSLRERLQKAieeeeaRMRe 1229
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAE-----LEELRLELEELELELEEA------QAE- 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1230 eesqrlswLRAQVQSSTQADEDQIRA-EQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAA 1308
Cdd:COG1196    290 --------EYELLAELARLEQDIARLeERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1309 KEKALQQLREQLEGERKEAVATLEKEHSAELERlcsslEAKHREVVSSLQKKIQEAQQKEEAQLQKclgqvehrvhqksy 1388
Cdd:COG1196    362 EAEEALLEAEAELAEAEEELEELAEELLEALRA-----AAELAAQLEELEEAEEALLERLERLEEE-------------- 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1389 hVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVR 1468
Cdd:COG1196    423 -LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1469 QEQHKRLEDLRRRHREQERKLQ---DLELDLETRAKDV---KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATH 1542
Cdd:COG1196    502 DYEGFLEGVKAALLLAGLRGLAgavAVLIGVEAAYEAAleaALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDK 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1543 QQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHfSSLEAEAQKKQHLLREVTVEENNASPHF 1622
Cdd:COG1196    582 IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL-EAALRRAVTLAGRLREVTLEGEGGSAGG 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1623 EPDLHIE-DLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQ 1701
Cdd:COG1196    661 SLTGGSRrELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 2462523724 1702 HWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEM 1740
Cdd:COG1196    741 LLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

1161-1769

7.89e-15

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 80.78 E-value: 7.89e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1161 EEAVAQVLEQDQRHLLESKQEKMQQLREKLCQeeeeeILRLHQQKEQSLSSLRERLQKAieeeeaRMREEESQRLSWLRA 1240
Cdd:TIGR00618  199 LTLRSQLLTLCTPCMPDTYHERKQVLEKELKH-----LREALQQTQQSHAYLTQKREAQ------EEQLKKQQLLKQLRA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1241 QVQSSTQadedqiraeQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALnaakEKALQQLREQL 1320
Cdd:TIGR00618  268 RIEELRA---------QEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSR----AKLLMKRAAHV 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1321 egerkeavatlekEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSL 1400
Cdd:TIGR00618  335 -------------KQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1401 lrekrqevegeherrLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRR 1480
Cdd:TIGR00618  402 ---------------LDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQ 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1481 RHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLL--DVQRQVALKSEEATATHQQLEEaqkEHTHLLQS 1558
Cdd:TIGR00618  467 SLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIhpNPARQDIDNPGPLTRRMQRGEQ---TYAQLETS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1559 NQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREV---TVEENNASPHFEPDLHIEDLRKSL 1635
Cdd:TIGR00618  544 EEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLqdlTEKLSEAEDMLACEQHALLRKLQP 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1636 GTNQtKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGV--ALRSAKEFlvqQTRSMRRRQTALKAAQQ------HWRHEL 1707
Cdd:TIGR00618  624 EQDL-QDVRLHLQQCSQELALKLTALHALQLTLTQERVreHALSIRVL---PKELLASRQLALQKMQSekeqltYWKEML 699

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462523724 1708 ASAQEvakdppgikALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEA 1769
Cdd:TIGR00618  700 AQCQT---------LLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA 752

PRK02224

DNA double-strand break repair Rad50 ATPase;

1155-1580

8.40e-15

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 80.47 E-value: 8.40e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1155 AALKAMEEAVAQVLEQDQRhlLESKQEKMQQLREKLcqeeeEEILRLHQQKEQSLSSLR---ERLQKAIEEEEARMREEe 1231
Cdd:PRK02224   206 ERLNGLESELAELDEEIER--YEEQREQARETRDEA-----DEVLEEHEERREELETLEaeiEDLRETIAETEREREEL- 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1232 SQRLSWLRAQVQ------SSTQADEDQIRAEQEASLQKlREELESQQKAERASLEQKnRQMLEQLKEEIE---------- 1295
Cdd:PRK02224   278 AEEVRDLRERLEeleeerDDLLAEAGLDDADAEAVEAR-REELEDRDEELRDRLEEC-RVAAQAHNEEAEslredaddle 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1296 --ASEKSEQAAlnaAKEKALQQLREQLEgERKEAVATLEKE-----------------HSAELERLCSSLEAKHREV--- 1353
Cdd:PRK02224   356 erAEELREEAA---ELESELEEAREAVE-DRREEIEELEEEieelrerfgdapvdlgnAEDFLEELREERDELREREael 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1354 ---VSSLQKKIQEAQQKEEAQlqKC--LGQ-VEHRVH-----QKSYHVAGYEHELSSLlREKRQEVEGEHER-------- 1414
Cdd:PRK02224   432 eatLRTARERVEEAEALLEAG--KCpeCGQpVEGSPHvetieEDRERVEELEAELEDL-EEEVEEVEERLERaedlveae 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1415 -RLDKMKEEHQQVMAKAREQYE-AEERKQRAELLGHLTGELErlqrAHERELETVRQEQHKRLEDLRRRHREQERKLQDL 1492
Cdd:PRK02224   509 dRIERLEERREDLEELIAERREtIEEKRERAEELRERAAELE----AEAEEKREAAAEAEEEAEEAREEVAELNSKLAEL 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1493 ELDLEtRAKDVKARLALLEVQEETA-----RREKQQLLDVQRQVALKSE-------EATATHQQLEEAQKEHTHLLQSNQ 1560
Cdd:PRK02224   585 KERIE-SLERIRTLLAAIADAEDEIerlreKREALAELNDERRERLAEKrerkrelEAEFDEARIEEAREDKERAEEYLE 663

                          490       500
                   ....*....|....*....|
gi 2462523724 1561 QLREILDELQARKLKLESQV 1580
Cdd:PRK02224   664 QVEEKLDELREERDDLQAEI 683

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

1256-1573

1.11e-14

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 79.78 E-value: 1.11e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1256 EQEASLQKLREELESQQKAERASLEQKNRQMLE-----QLKEEIEASEKSEQAALNAAKEKALQQLREQ-----LEGERK 1325
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEaekarQAEMDRQAAIYAEQERMAMERERELERIRQEerkreLERIRQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1326 EAVAtLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQlqkclgqveHRVHQKSYHVAGYEHELSSLLREKR 1405
Cdd:pfam17380  368 EEIA-MEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQ---------RKIQQQKVEMEQIRAEQEEARQREV 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1406 QEVEGEHERRLDKMKEEH---QQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQHKRLEDLRRRH 1482
Cdd:pfam17380  438 RRLEEERAREMERVRLEEqerQQQVERLRQQEEERKRKKL---------ELEKEKRDRKRAEEQRRKILEKELEERKQAM 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1483 REQERKLQDLELDLETRAKDVKARLALLEVQEEtarREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHthllqsnQQL 1562
Cdd:pfam17380  509 IEEERKRKLLEKEMEERQKAIYEEERRREAEEE---RRKQQEMEERRRIQEQMRKATEERSRLEAMERER-------EMM 578

                          330
                   ....*....|.
gi 2462523724 1563 REILDELQARK 1573
Cdd:pfam17380  579 RQIVESEKARA 589

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1250-1579

4.07e-14

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.56 E-value: 4.07e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1250 EDQIRAEQE--ASLQKLREELESQQKaeraSLEQKNRQMlEQLKEeIEASEKSEQAALNAAKEKALQQLREQLEGERKEA 1327
Cdd:TIGR02168  178 ERKLERTREnlDRLEDILNELERQLK----SLERQAEKA-ERYKE-LKAELRELELALLVLRLEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1328 VaTLEKEHSAELERLCSSLEAkHREVVSSLQKKIQEAQQKEEA---QLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREK 1404
Cdd:TIGR02168  252 E-EELEELTAELQELEEKLEE-LRLEVSELEEEIEELQKELYAlanEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1405 RQEVE-GEHERRLDKMKEEHQQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQH---KRLEDLRR 1480
Cdd:TIGR02168  330 SKLDElAEELAELEEKLEELKEELESLEAELEELEAELE---------ELESRLEELEEQLETLRSKVAqleLQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1481 RHREQERKLQDLEldlETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATH-QQLEEAQKEHTHLLQSN 1559
Cdd:TIGR02168  401 EIERLEARLERLE---DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLeEALEELREELEEAEQAL 477

                          330       340
                   ....*....|....*....|
gi 2462523724 1560 QQLREILDELQARKLKLESQ 1579
Cdd:TIGR02168  478 DAAERELAQLQARLDSLERL 497

PTZ00121

MAEBL; Provisional

1043-1526

7.54e-14

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.87 E-value: 7.54e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1043 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAE 1122
Cdd:PTZ00121  1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1123 DPEEkvavspTPPVSPEVRSTEPVappEQLSEAALKAmEEAVAQVLEQDQRHLLESKQE---KMQQLREKLCQEEEEEIL 1199
Cdd:PTZ00121  1419 KADE------AKKKAEEKKKADEA---KKKAEEAKKA-DEAKKKAEEAKKAEEAKKKAEeakKADEAKKKAEEAKKADEA 1488

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1200 RLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRaQVQSSTQADEDQiRAEQEASLQKLR--EEL---ESQQKA 1274
Cdd:PTZ00121  1489 KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-KAEEAKKADEAK-KAEEKKKADELKkaEELkkaEEKKKA 1566

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1275 ERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKeavatlEKEHSAELERlcsslEAKHREVV 1354
Cdd:PTZ00121  1567 EEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE------AKIKAEELKK-----AEEEKKKV 1635

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1355 SSLQKKIQEAQQKEEaQLQKclgqvehrvhqksyhvagyEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQY 1434
Cdd:PTZ00121  1636 EQLKKKEAEEKKKAE-ELKK-------------------AEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALK 1695

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1435 EAEERKQRAEllghltgELERLQRAHERELETVRQEQHKR---LEDLRRRHREQERKLQDLELDlETRAKDVKARLALLE 1511
Cdd:PTZ00121  1696 KEAEEAKKAE-------ELKKKEAEEKKKAEELKKAEEENkikAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEE 1767

                          490
                   ....*....|....*
gi 2462523724 1512 VQEETARREKQQLLD 1526
Cdd:PTZ00121  1768 KKAEEIRKEKEAVIE 1782

PTZ00121

MAEBL; Provisional

1102-1768

1.29e-13

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.10 E-value: 1.29e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1102 EKGKEQHSQAEELGPGQEEAEDPEEKVAvsptppvSPEVRSTEPVAPPEQLSEAalkamEEAvaQVLEQDQRHLLESKQE 1181
Cdd:PTZ00121  1096 AFGKAEEAKKTETGKAEEARKAEEAKKK-------AEDARKAEEARKAEDARKA-----EEA--RKAEDAKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1182 KMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAqvqsstqadEDQIRAEQEASL 1261
Cdd:PTZ00121  1162 DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKA---------EDAKKAEAVKKA 1232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1262 QKLREELESQQKAEraslEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGER-KEAVATLEKEHSAELE 1340
Cdd:PTZ00121  1233 EEAKKDAEEAKKAE----EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKaDEAKKAEEKKKADEAK 1308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1341 RlcsslEAKHREVVSSLQKKIQEAQQKEEAQLQKClgqvehRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMK 1420
Cdd:PTZ00121  1309 K-----KAEEAKKADEAKKKAEEAKKKADAAKKKA------EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAK 1377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1421 EEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRA 1500
Cdd:PTZ00121  1378 KKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK 1457

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1501 KDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHthllQSNQQLREILDELQARKLKLESQV 1580
Cdd:PTZ00121  1458 KAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAEEA 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1581 DLLQAQSQQLQKHfsslEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKslgtnqtkevSSSLSQSKEDLYLDSLS 1660
Cdd:PTZ00121  1534 KKADEAKKAEEKK----KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK----------AEEAKKAEEARIEEVMK 1599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1661 SHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAK--DPPGIKALEDMRKNlEKETRHLD 1738
Cdd:PTZ00121  1600 LYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKaeEENKIKAAEEAKKA-EEDKKKAE 1678

                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 2462523724 1739 EMKSA---MRKGHNLLKKKEE---KLNQLESSLWEE 1768
Cdd:PTZ00121  1679 EAKKAeedEKKAAEALKKEAEeakKAEELKKKEAEE 1714

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1157-1654

1.66e-13

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 76.49 E-value: 1.66e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1157 LKAMEEAVAQVLEQdQRHL--LESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKaieeeearmreeesqr 1234
Cdd:COG4913    237 LERAHEALEDAREQ-IELLepIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEE---------------- 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1235 lswLRAQVQSsTQADEDQIRAEQEASLQKLREelesqqkAERASLEQKNRQmLEQLKEEIEASEKSEQAALNAAK--EKA 1312
Cdd:COG4913    300 ---LRAELAR-LEAELERLEARLDALREELDE-------LEAQIRGNGGDR-LEQLEREIERLERELEERERRRArlEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1313 LQQLREQLEGERkEAVATLEKEHSAELERLcSSLEAKHREVVSSLQKKIQEAQqKEEAQLQKCLGQVEHRVHQKSYHVAG 1392
Cdd:COG4913    368 LAALGLPLPASA-EEFAALRAEAAALLEAL-EEELEALEEALAEAEAALRDLR-RELRELEAEIASLERRKSNIPARLLA 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1393 YEHELSSLLREKRQE---------------------------------VEGEHERR----LDKMKEEHQQVMAKAREQYE 1435
Cdd:COG4913    445 LRDALAEALGLDEAElpfvgelievrpeeerwrgaiervlggfaltllVPPEHYAAalrwVNRLHLRGRLVYERVRTGLP 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1436 AEERKQRAEllGHLTGELE------------RLQR-------AHERELETVRQ---------EQHKRLE-DLRRRHREQ- 1485
Cdd:COG4913    525 DPERPRLDP--DSLAGKLDfkphpfrawleaELGRrfdyvcvDSPEELRRHPRaitragqvkGNGTRHEkDDRRRIRSRy 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1486 ------ERKLQDLELD---LETRAKDVKARLALLEVQEETARREKQQLLDVQrQVALKSEEATATHQQLEEAQKEHTHLL 1556
Cdd:COG4913    603 vlgfdnRAKLAALEAElaeLEEELAEAEERLEALEAELDALQERREALQRLA-EYSWDEIDVASAEREIAELEAELERLD 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1557 QSN---QQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVtveENNASPHFEPDLhIEDLRK 1633
Cdd:COG4913    682 ASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA---EDLARLELRALL-EERFAA 757

                          570       580
                   ....*....|....*....|.
gi 2462523724 1634 SLGTNQTKEVSSSLSQSKEDL 1654
Cdd:COG4913    758 ALGDAVERELRENLEERIDAL 778

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1086-1611

2.04e-13

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 76.25 E-value: 2.04e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1086 QLSLQREQAPSppAACEKGKEQHSQAEELGPGQEEAEDPEEKVAvsptppvspEVRSTEPVAppEQLSEAALKAMEE--- 1162
Cdd:TIGR02168  320 ELEAQLEELES--KLDELAEELAELEEKLEELKEELESLEAELE---------ELEAELEEL--ESRLEELEEQLETlrs 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1163 AVAQVLEQ-----DQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEEsQRLSW 1237
Cdd:TIGR02168  387 KVAQLELQiaslnNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLE-EALEE 465

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1238 LRAQVQSSTQA------DEDQIRAEQeASLQKLREELESQQKAERASLEQKNR--QMLEQLKEEIEASEKSEqAALNAAK 1309
Cdd:TIGR02168  466 LREELEEAEQAldaaerELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGlsGILGVLSELISVDEGYE-AAIEAAL 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1310 EKALQQLREQLEGERKEAVATLEKEHS-----AELERLC-SSLEAKHRE------------------------------- 1352
Cdd:TIGR02168  544 GGRLQAVVVENLNAAKKAIAFLKQNELgrvtfLPLDSIKgTEIQGNDREilkniegflgvakdlvkfdpklrkalsyllg 623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1353 ---VVSSLQ------KKIQE------------------------------AQQKEEAQLQKCLGQVEHRVHQKSYHVAGY 1393
Cdd:TIGR02168  624 gvlVVDDLDnalelaKKLRPgyrivtldgdlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELEKALAEL 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1394 EHELSSLLREKRQevegeherrLDKMKEEHQQVMAKAREQYEAEERKQRAellghLTGELERLQRAHErELETVRQEQHK 1473
Cdd:TIGR02168  704 RKELEELEEELEQ---------LRKELEELSRQISALRKDLARLEAEVEQ-----LEERIAQLSKELT-ELEAEIEELEE 768

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1474 RLEDLRRRHREQERKLQDLELDLETRAKDVKA-RLALLEVQEEtARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEH 1552
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKAlREALDELRAE-LTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462523724 1553 THLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREV 1611
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL 906

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1161-1572

4.48e-13

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.09 E-value: 4.48e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1161 EEAVAQVLEQDQRHL-LESKQEKMQQLREKLcQEEEEEILRLHQQKEQSLSSLRERLQkaieeeearmreEESQRLSWLR 1239
Cdd:TIGR02168  666 AKTNSSILERRREIEeLEEKIEELEEKIAEL-EKALAELRKELEELEEELEQLRKELE------------ELSRQISALR 732

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1240 AQVQSSTQadEDQIRAEQEASLQKLREELEsQQKAERASLEQKNRQMLEQLKEEIEasekSEQAALNAAKEkALQQLREQ 1319
Cdd:TIGR02168  733 KDLARLEA--EVEQLEERIAQLSKELTELE-AEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKE-ELKALREA 804

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1320 LEGERKEavATLEKEHSAELERLCSSLEAKHREVVSSLQkkiQEAQQKEEAQLQkclgqvehrvhqksyhVAGYEHELSS 1399
Cdd:TIGR02168  805 LDELRAE--LTLLNEEAANLRERLESLERRIAATERRLE---DLEEQIEELSED----------------IESLAAEIEE 863

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1400 lLREKRQEVEGEHErRLDKMKEEHQQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQHK---RLE 1476
Cdd:TIGR02168  864 -LEELIEELESELE-ALLNERASLEEALALLRSELEELSEELR---------ELESKRSELRRELEELREKLAQlelRLE 932

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1477 DLR-RRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRqVALKS-EEATATHQQLEEAQKEHTH 1554
Cdd:TIGR02168  933 GLEvRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP-VNLAAiEEYEELKERYDFLTAQKED 1011

                          410
                   ....*....|....*...
gi 2462523724 1555 LLQSNQQLREILDELQAR 1572
Cdd:TIGR02168 1012 LTEAKETLEEAIEEIDRE 1029

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

1013-1569

6.71e-13

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 74.23 E-value: 6.71e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1013 DSQSSQDELQSKQSKGLEERYHR---LSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKE-AEELGEDSAASLSLQLS 1088
Cdd:TIGR00618  308 QAQRIHTELQSKMRSRAKLLMKRaahVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREiSCQQHTLTQHIHTLQQQ 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1089 LQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVL 1168
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQS 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1169 EQDQRHLLESKQEKMQQLREKlcQEEEEEILRLHQQKEQSL-SSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQ 1247
Cdd:TIGR00618  468 LKEREQQLQTKEQIHLQETRK--KAVVLARLLELQEEPCPLcGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE 545

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1248 ADEDQIRAEQEaSLQKLREELESQQKAERASLEQKNR--QMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK 1325
Cdd:TIGR00618  546 DVYHQLTSERK-QRASLKEQMQEIQQSFSILTQCDNRskEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPE 624

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1326 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEA-----QQKEE--AQLQKCLGQVEHRVHQKSYHVAGYEHELS 1398
Cdd:TIGR00618  625 QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHalsirVLPKEllASRQLALQKMQSEKEQLTYWKEMLAQCQT 704

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1399 sLLREkrqevEGEHERRLDKMKEEHQQVMAKAREQYEAEE----------RKQRAELLGHLTGELERLQRAHERELETVR 1468
Cdd:TIGR00618  705 -LLRE-----LETHIEEYDREFNEIENASSSLGSDLAAREdalnqslkelMHQARTVLKARTEAHFNNNEEVTAALQTGA 778

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1469 QEQHKRlEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEA 1548
Cdd:TIGR00618  779 ELSHLA-AEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEEC 857

                          570       580
                   ....*....|....*....|.
gi 2462523724 1549 QKEHTHLLQSNQQLREILDEL 1569
Cdd:TIGR00618  858 SKQLAQLTQEQAKIIQLSDKL 878

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1154-1527

4.69e-12

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 71.63 E-value: 4.69e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1154 EAALKAMEEAVAQVleQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQsLSSLRERLQKAieeeearmreeeSQ 1233
Cdd:TIGR02168  683 EEKIEELEEKIAEL--EKALAELRKELEELEEELEQLRKELEELSRQISALRKD-LARLEAEVEQL------------EE 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1234 RLSWLRAQVQSSTQADEDQIRAEQEASLQKLREElesqqkAERASLEQKNRQMLEQLKEEIEASeKSEQAALNAAKEKAl 1313
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAE------AEIEELEAQIEQLKEELKALREAL-DELRAELTLLNEEA- 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1314 QQLREQLEGERKEAVATlekehSAELERLCSSLEAKhREVVSSLQKKIQEAQQKEEAQlqkclgQVEHRVHQKSYHVAGY 1393
Cdd:TIGR02168  820 ANLRERLESLERRIAAT-----ERRLEDLEEQIEEL-SEDIESLAAEIEELEELIEEL------ESELEALLNERASLEE 887

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1394 EHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKareQYEAEERKQRAELLghLTGELERLQRAHERELETVRQEQHK 1473
Cdd:TIGR02168  888 ALALLRSELEELSEELRELESKRSELRRELEELREK---LAQLELRLEGLEVR--IDNLQERLSEEYSLTLEEAEALENK 962

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1474 RLED---LRRRHREQERKLQDL---ELDLETRAKDVKARLALLEVQEETARREKQQLLDV 1527
Cdd:TIGR02168  963 IEDDeeeARRRLKRLENKIKELgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1154-1569

5.19e-12

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 70.95 E-value: 5.19e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1154 EAALKAMEEAVAQVLE-QDQRHLLESKQEKMQQLREKLCQEEEE-EILRLHQQKEQSLSSLRERLQkaieeeearmreEE 1231
Cdd:COG4717     77 EEELKEAEEKEEEYAElQEELEELEEELEELEAELEELREELEKlEKLLQLLPLYQELEALEAELA------------EL 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1232 SQRLSWLRAQVQSSTQADEDQIRAEQEasLQKLREELESQQKAERASLEQKNRQMLEQLkEEIEASEKSEQAALNAAKEK 1311
Cdd:COG4717    145 PERLEELEERLEELRELEEELEELEAE--LAELQEELEELLEQLSLATEEELQDLAEEL-EELQQRLAELEEELEEAQEE 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1312 aLQQLREQLEGERKEAVATLEKEHSAELERL-------------------------------------CSSLEAKHREVV 1354
Cdd:COG4717    222 -LEELEEELEQLENELEAAALEERLKEARLLlliaaallallglggsllsliltiagvlflvlgllalLFLLLAREKASL 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1355 SSLQKKIQEAQQK---EEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKA- 1430
Cdd:COG4717    301 GKEAEELQALPALeelEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAg 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1431 ----------------REQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLEL 1494
Cdd:COG4717    381 vedeeelraaleqaeeYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEA 460

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462523724 1495 DLETRAKDvkARLALLEVQEETARREKQQLldVQRQVALKseeatATHQQLEEAQKEHTHLLQS--NQQLREILDEL 1569
Cdd:COG4717    461 ELEQLEED--GELAELLQELEELKAELREL--AEEWAALK-----LALELLEEAREEYREERLPpvLERASEYFSRL 528

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

1176-1764

5.88e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 71.30 E-value: 5.88e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1176 LESKQEKMQQLREKLCQeeeeeilrLHQQKEQSLSSLRERLQKAIEEEEARMReeesqrlswLRAQVQSSTQADEDQIRA 1255
Cdd:pfam15921  115 LQTKLQEMQMERDAMAD--------IRRRESQSQEDLRNQLQNTVHELEAAKC---------LKEDMLEDSNTQIEQLRK 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1256 ---EQEASLQKLR------EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLrEQLEGERKE 1326
Cdd:pfam15921  178 mmlSHEGVLQEIRsilvdfEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQL-EALKSESQN 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1327 AVATLEKEHSAELERLCSSLE----------AKHREVVSSLQKK---IQEAQQKEEAQLQKCLGQVEHRVHQksyhvagy 1393
Cdd:pfam15921  257 KIELLLQQHQDRIEQLISEHEveitgltekaSSARSQANSIQSQleiIQEQARNQNSMYMRQLSDLESTVSQ-------- 328

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1394 eheLSSLLREKRQEVEgeherrlDKMKEEHQQVMAKAREQYEAE-ERKQRAELLGHLTGELERL-QRAHERELE-TVRQE 1470
Cdd:pfam15921  329 ---LRSELREAKRMYE-------DKIEELEKQLVLANSELTEARtERDQFSQESGNLDDQLQKLlADLHKREKElSLEKE 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1471 QHKRLEDlrrRHREQERKLQDLELDLETRAKDVKARLALLE-VQEETARREKQQLLDVQrqvalkseeatATHQQLEEAQ 1549
Cdd:pfam15921  399 QNKRLWD---RDTGNSITIDHLRRELDDRNMEVQRLEALLKaMKSECQGQMERQMAAIQ-----------GKNESLEKVS 464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1550 KEHTHLLQSNQQLREILDELQARKLKLESqvdllqaqsqqLQKHFSSLEAEAQKKQHLLR----EVTVEENNASPHFEPD 1625
Cdd:pfam15921  465 SLTAQLESTKEMLRKVVEELTAKKMTLES-----------SERTVSDLTASLQEKERAIEatnaEITKLRSRVDLKLQEL 533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1626 LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSH--NVWHLLSAEGvalRSAKEFLVQQTRsmrrrqtaLKAAQQHW 1703
Cdd:pfam15921  534 QHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQieNMTQLVGQHG---RTAGAMQVEKAQ--------LEKEINDR 602

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462523724 1704 RHELASAQEVA-KDPPGIKALEDMRKNLEKETRHLDEMKSA-MRKGHNLLKKKEEKLNQLESS 1764
Cdd:pfam15921  603 RLELQEFKILKdKKDAKIRELEARVSDLELEKVKLVNAGSErLRAVKDIKQERDQLLNEVKTS 665

PRK02224

DNA double-strand break repair Rad50 ATPase;

1102-1493

9.52e-12

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 70.45 E-value: 9.52e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1102 EKGKEQHSQAEELGpgqEEAEDPEEKVavsptppvspEVRSTEPVAPPEQLsEAALKAMEEAVAQVLEQDQRhlLESKQE 1181
Cdd:PRK02224   356 ERAEELREEAAELE---SELEEAREAV----------EDRREEIEELEEEI-EELRERFGDAPVDLGNAEDF--LEELRE 419

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1182 KMQQLREKLCQEeeeeilrlhqqkEQSLSSLRERLQKAIEEEEARMREEESQrlswlraQVQSSTQADEDQIRAEQEASL 1261
Cdd:PRK02224   420 ERDELREREAEL------------EATLRTARERVEEAEALLEAGKCPECGQ-------PVEGSPHVETIEEDRERVEEL 480

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1262 QKLREELESQQ-----KAERASLEQKNRQMLEQLKEEIEASEK--SEQAALNAAKEKALQQLREQLEGERKEAVATLEKE 1334
Cdd:PRK02224   481 EAELEDLEEEVeeveeRLERAEDLVEAEDRIERLEERREDLEEliAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1335 HSAELErlcsslEAKHREVVSSLQKKIQEAQQKEEAqlqkcLGQVEHRVHQksyhVAGYEHELSSLlREKR---QEVEGE 1411
Cdd:PRK02224   561 AEAEEE------AEEAREEVAELNSKLAELKERIES-----LERIRTLLAA----IADAEDEIERL-REKRealAELNDE 624

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1412 HERRLDKMKEEHQQVMAKAREQY--EAEERKQRAE-LLGHLTGELERLqRAHERELET----VRQEQhKRLEDLRRRHRE 1484
Cdd:PRK02224   625 RRERLAEKRERKRELEAEFDEARieEAREDKERAEeYLEQVEEKLDEL-REERDDLQAeigaVENEL-EELEELRERREA 702


                   ....*....
gi 2462523724 1485 QERKLQDLE 1493
Cdd:PRK02224   703 LENRVEALE 711

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1176-1580

1.27e-11

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 69.80 E-value: 1.27e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1176 LESKQEKMQQLREKLcqeeeeeilRLHQQKEQSLSSLRERLQKAieeeeARMREEESQRLSWLRAQVQsstQADEDQIRA 1255
Cdd:COG4717     73 LKELEEELKEAEEKE---------EEYAELQEELEELEEELEEL-----EAELEELREELEKLEKLLQ---LLPLYQELE 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1256 EQEASLQKLREELES--QQKAERASLEQKNRQMLEQLkEEIEASEKSEQAALNAAKEKALQQLREQLEgERKEAVATLEK 1333
Cdd:COG4717    136 ALEAELAELPERLEEleERLEELRELEEELEELEAEL-AELQEELEELLEQLSLATEEELQDLAEELE-ELQQRLAELEE 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1334 EhSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQV------EHRVHQKSYHVAGYEHELSSLLREKRQE 1407
Cdd:COG4717    214 E-LEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALlallglGGSLLSLILTIAGVLFLVLGLLALLFLL 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1408 VEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQER 1487
Cdd:COG4717    293 LAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEI 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1488 KlqdlELDLETRAKDVKARLALLEvQEETARREKQQLLDVQRQVA--LKSEEATATHQQLEEAQKEHTHLLQSNQQLREI 1565
Cdd:COG4717    373 A----ALLAEAGVEDEEELRAALE-QAEEYQELKEELEELEEQLEelLGELEELLEALDEEELEEELEELEEELEELEEE 447

                          410
                   ....*....|....*
gi 2462523724 1566 LDELQARKLKLESQV 1580
Cdd:COG4717    448 LEELREELAELEAEL 462

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1150-1527

1.54e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 69.97 E-value: 1.54e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1150 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLcQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMRE 1229
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL-AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1230 EESQRLSW---LRAQVQSSTQADEDQIRAEQEASLQKLREELEsQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALN 1306
Cdd:COG1196    525 AVAVLIGVeaaYEAALEAALAAALQNIVVEDDEVAAAAIEYLK-AAKAGRATFLPLDKIRARAALAAALARGAIGAAVDL 603

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1307 AAKEKALQQLREQLEGERkEAVATLEKEHSAELERLCSSLEAKHREVvSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQK 1386
Cdd:COG1196    604 VASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREV-TLEGEGGSAGGSLTGGSRRELLAALLEAEAEL 681

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1387 SyhvagyehELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELET 1466
Cdd:COG1196    682 E--------ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL 753

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462523724 1467 VRQEQHKRLEDLRRRHREQERKLQDLE---LDLETRAKDVKARLALLEVQEETARREKQQLLDV 1527
Cdd:COG1196    754 EELPEPPDLEELERELERLEREIEALGpvnLLAIEEYEELEERYDFLSEQREDLEEARETLEEA 817

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1297-1635

1.71e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 69.71 E-value: 1.71e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1297 SEKSEQAALNAAKEKA-LQQLREQLEGERKEAVATLEKEHSAELER--LCSSLEAKHREVvSSLQKKIQEAQQKEEAQLQ 1373
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAeLQRLRERLEGLKRELSSLQSELRRIENRLdeLSQELSDASRKI-GEIEKEIEQLEQEEEKLKE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1374 KcLGQVEHRVHQKSyhvagyehelssllrEKRQEVEGEHERrLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGEL 1453
Cdd:TIGR02169  738 R-LEELEEDLSSLE---------------QEIENVKSELKE-LEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAEL 800

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1454 erlqraheRELETVRQEQHKRLEDLrrrhreqERKLQDLELDLEtrakdvkarLALLEVQEETARRE--KQQLLDVQRQV 1531
Cdd:TIGR02169  801 --------SKLEEEVSRIEARLREI-------EQKLNRLTLEKE---------YLEKEIQELQEQRIdlKEQIKSIEKEI 856

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1532 ALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREV 1611
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI 936

                          330       340
                   ....*....|....*....|....
gi 2462523724 1612 TVEENNASPHFEPDLHIEDLRKSL 1635
Cdd:TIGR02169  937 EDPKGEDEEIPEEELSLEDVQAEL 960

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1150-1772

1.95e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 69.62 E-value: 1.95e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1150 EQLSEAALKAMEEAVAQVLEQDQRHLLEsKQEKMQQLREKLCQ--EEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARM 1227
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELK-LQELKLKEQAKKALeyYQLKEKLELEEEYLL-YLDYLKLNEERIDLLQELL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1228 REEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM------LEQLKEEIEASEKSE 1301
Cdd:pfam02463  247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLerrkvdDEEKLKESEKEKKKA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1302 QAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkCLGQVEH 1381
Cdd:pfam02463  327 EKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-LKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1382 RVHQKSYHVAGYEHELSSLLREKRQEVEGEhERRLDKMKEEHQQVMAKAREQYEAEERKQRAEllghltgELERLQRAHE 1461
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEE-EESIELKQGKLTEEKEELEKQELKLLKDELEL-------KKSEDLLKET 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1462 RELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALkSEEATAT 1541
Cdd:pfam02463  478 QLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV-IVEVSAT 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1542 HQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKhfsSLEAEAQKKQHLLREVTVEEnNASPH 1621
Cdd:pfam02463  557 ADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQ---LDKATLEADEDDKRAKVVEG-ILKDT 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1622 FEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSshnvwhLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQ 1701
Cdd:pfam02463  633 ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSEL------TKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462523724 1702 HWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEASDE 1772
Cdd:pfam02463  707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1410-1778

2.60e-11

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 69.32 E-value: 2.60e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1410 GEHERRLDKMKEEHQQVMaKAREQYEAEERKQRAELLGHLT---GELERLQRAHER------ELETVRQEQHKRLEDLRR 1480
Cdd:TIGR02168  196 NELERQLKSLERQAEKAE-RYKELKAELRELELALLVLRLEelrEELEELQEELKEaeeeleELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1481 RHREQERKLQDLEldleTRAKDVKARLALLEVQEETARREKQQLldvQRQVALKSEEATATHQQLEEAQKEHThllqsnq 1560
Cdd:TIGR02168  275 EVSELEEEIEELQ----KELYALANEISRLEQQKQILRERLANL---ERQLEELEAQLEELESKLDELAEELA------- 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1561 QLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEP-DLHIEDLRKSLgtNQ 1639
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERlEARLERLEDRR--ER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1640 TKEVSSSLSQSKEDLYLDSLSSHNVwhLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEvakdppG 1719
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAELE--ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA------R 490

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462523724 1720 IKALEDMRKNLEKETRhldemksamrkGHNLLKKKEEKLNQLESSLWE--------EASDEGTLGGS 1778
Cdd:TIGR02168  491 LDSLERLQENLEGFSE-----------GVKALLKNQSGLSGILGVLSElisvdegyEAAIEAALGGR 546

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

1271-1579

5.99e-11

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 66.10 E-value: 5.99e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1271 QQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEgerkeavatlEKEHSAELERLcssLEAKH 1350
Cdd:pfam13868   33 RIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIE----------EREQKRQEEYE---EKLQE 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1351 REVVSSLQKKIQEAQQKEEAQLQKclgqvehRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKA 1430
Cdd:pfam13868  100 REQMDEIVERIQEEDQAEAEEKLE-------KQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEERE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1431 REQYEAEERKQR-AELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDlETRAKDVKARLAL 1509
Cdd:pfam13868  173 AEREEIEEEKEReIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQ-QAREEQIELKERR 251

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462523724 1510 LEVQEETARREKQQLLDVQR-QVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR--EILDELQARKLKLESQ 1579
Cdd:pfam13868  252 LAEEAEREEEEFERMLRKQAeDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRaaEREEELEEGERLREEE 324

PRK03918

DNA double-strand break repair ATPase Rad50;

1244-1762

1.01e-10

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 67.01 E-value: 1.01e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1244 SSTQADEDQIRAEQEASLQKLRE--ELESQQKAERASLE--QKNRQMLEQLKEEIEASEKSEQAALNAAK--EKALQQLR 1317
Cdd:PRK03918   186 KRTENIEELIKEKEKELEEVLREinEISSELPELREELEklEKEVKELEELKEEIEELEKELESLEGSKRklEEKIRELE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1318 EQLEGERKE-------------------AVATLEKEHSAELERL--CSSLEAKHREVVSSLQKKIQEAQQKEE--AQLQK 1374
Cdd:PRK03918   266 ERIEELKKEieeleekvkelkelkekaeEYIKLSEFYEEYLDELreIEKRLSRLEEEINGIEERIKELEEKEErlEELKK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1375 CLGQVEHRVHQKSYHVAGYEhELSSLLREKRQEVEGEHERRLDKMKEEHQQVmAKAREQYEAEERKQRAELlGHLTGELE 1454
Cdd:PRK03918   346 KLKELEKRLEELEERHELYE-EAKAKKEELERLKKRLTGLTPEKLEKELEEL-EKAKEEIEEEISKITARI-GELKKEIK 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1455 RLQRAHErELETVRQ---------EQHKRLEDLRRRHREQERKLQDLElDLETRAKDVKARLALLEVQeetarREKQQLL 1525
Cdd:PRK03918   423 ELKKAIE-ELKKAKGkcpvcgrelTEEHRKELLEEYTAELKRIEKELK-EIEEKERKLRKELRELEKV-----LKKESEL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1526 DVQRQVA--LKSEEATATHQQLEEAQKEHTHLlqsnQQLREILDELQARKLKLESQVdllqaqsqqlqkhfSSLEAEAQK 1603
Cdd:PRK03918   496 IKLKELAeqLKELEEKLKKYNLEELEKKAEEY----EKLKEKLIKLKGEIKSLKKEL--------------EKLEELKKK 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1604 KQHLLREV-TVEENNASphfepdlhIEDLRKSLGTNQTKEVSSSLsQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFL 1682
Cdd:PRK03918   558 LAELEKKLdELEEELAE--------LLKELEELGFESVEELEERL-KELEPFYNEYLELKDAEKELEREEKELKKLEEEL 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1683 VQ----------QTRSMRRRQTALKAAQQHWRHE------LASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRK 1746
Cdd:PRK03918   629 DKafeelaetekRLEELRKELEELEKKYSEEEYEelreeyLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708

                          570
                   ....*....|....*.
gi 2462523724 1747 GHNLLKKKEEKLNQLE 1762
Cdd:PRK03918   709 AKKELEKLEKALERVE 724

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

1010-1537

2.36e-10

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 65.90 E-value: 2.36e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1010 DKDDSQSSQDELQSKQSKGLEERYHRLSPPLphEERAQSPPRSLATEEEPPQgpEGQPEWKEAEELGEDSAASLSlqlSL 1089
Cdd:pfam05483  268 DKANQLEEKTKLQDENLKELIEKKDHLTKEL--EDIKMSLQRSMSTQKALEE--DLQIATKTICQLTEEKEAQME---EL 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1090 QREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSpTPPVSPEVRSTEPVAPPEQLSEAALkameEAVAQVLE 1169
Cdd:pfam05483  341 NKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKII-TMELQKKSSELEEMTKFKNNKEVEL----EELKKILA 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1170 QDQRHLLESKQekMQQLREKLcqeeeeeilrlhQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQAD 1249
Cdd:pfam05483  416 EDEKLLDEKKQ--FEKIAEEL------------KGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELE 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1250 EDQIR-AEQEASLQKLR-EELESQQKAERASLEQKNRQ------------MLEQLkEEIEASEKSEQAALNAAKEKALQQ 1315
Cdd:pfam05483  482 KEKLKnIELTAHCDKLLlENKELTQEASDMTLELKKHQediinckkqeerMLKQI-ENLEEKEMNLRDELESVREEFIQK 560

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1316 -------LREQLEGERKEAVATLEKEHSAE-LERLCSSLeakhREVVSSLQKKIQEAQQKEEAQLQKC------LGQVEH 1381
Cdd:pfam05483  561 gdevkckLDKSEENARSIEYEVLKKEKQMKiLENKCNNL----KKQIENKNKNIEELHQENKALKKKGsaenkqLNAYEI 636

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1382 RVHQKSYHVAGYEHELSSLLREKRQEVEGE---HERRLDKMKEEHQQVMAKAREQYEAEERKQraellgHLTGELERLQR 1458
Cdd:pfam05483  637 KVNKLELELASAKQKFEEIIDNYQKEIEDKkisEEKLLEEVEKAKAIADEAVKLQKEIDKRCQ------HKIAEMVALME 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1459 AHERELETVRQEQHKRLEDLRRRHREQerklQDLELDLETRAKDVKARLALLEVQEETARREKQQL-LDVQRQVALKSEE 1537
Cdd:pfam05483  711 KHKHQYDKIIEERDSELGLYKNKEQEQ----SSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLkMEAKENTAILKDK 786

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1198-1769

2.50e-10

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 66.15 E-value: 2.50e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1198 ILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERA 1277
Cdd:pfam02463  164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQ 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1278 SLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQlreQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSL 1357
Cdd:pfam02463  244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEK---KLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1358 QKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYE-A 1436
Cdd:pfam02463  321 KEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELElK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1437 EERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEET 1516
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1517 ARREKQQLLDvqrqvaLKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSS 1596
Cdd:pfam02463  481 KLQEQLELLL------SRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVS 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1597 -LEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTnqtkevssslsqsKEDLYLDSLSSHNVWHLLSAEGVAL 1675
Cdd:pfam02463  555 aTADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAV-------------LEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1676 RSAKEFLVQQTRSMRRRQTALKAAQ--QHWRHELASAQEVAKDPPGIKALEDMRKN--LEKETRHLDEMKSAMRKGHNLL 1751
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESglRKGVSLEEGLAEKSEVKASLSELTKELLEiqELQEKAESELAKEEILRRQLEI 701

                          570
                   ....*....|....*...
gi 2462523724 1752 KKKEEKLNQLESSLWEEA 1769
Cdd:pfam02463  702 KKKEQREKEELKKLKLEA 719

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

1165-1507

2.52e-10

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 64.17 E-value: 2.52e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1165 AQVLEQDQRHLLESKQEK-----MQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLR 1239
Cdd:pfam13868   26 AQIAEKKRIKAEEKEEERrldemMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1240 AQVQssTQADEDQIRAEQEASLQKLREELEsQQKAERASLEQKNRQMLEQL----------KEEIEASEKSEQAALNAAK 1309
Cdd:pfam13868  106 IVER--IQEEDQAEAEEKLEKQRQLREEID-EFNEEQAEWKELEKEEEREEderileylkeKAEREEEREAEREEIEEEK 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1310 EKALQQLREQLEGERKeavatlEKEHSAEL--ERLCSSLEAKHRevvsslQKKIQEAQQKEEAQLQKCLGQVEHRVHqks 1387
Cdd:pfam13868  183 EREIARLRAQQEKAQD------EKAERDELraKLYQEEQERKER------QKEREEAEKKARQRQELQQAREEQIEL--- 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1388 yhvagyehelssllREKRQEVEGEHERRLDKMKEEHQQVMAKaREQYEAEERKQRaellghltgelerlQRAHERELETV 1467
Cdd:pfam13868  248 --------------KERRLAEEAEREEEEFERMLRKQAEDEE-IEQEEAEKRRMK--------------RLEHRRELEKQ 298

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 2462523724 1468 RQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARL 1507
Cdd:pfam13868  299 IEEREEQRAAEREEELEEGERLREEEAERRERIEEERQKK 338

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1151-1526

3.03e-10

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.86 E-value: 3.03e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1151 QLSEAALKAMEEAVAQVLE--QDQRHLLESKQEKMQQLREKLCQEeeeeiLRLHQQKEQSLSSLRERLQKaieeeearMR 1228
Cdd:TIGR02169  666 ILFSRSEPAELQRLRERLEglKRELSSLQSELRRIENRLDELSQE-----LSDASRKIGEIEKEIEQLEQ--------EE 732

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1229 EEESQRLSWLRAQVQSSTQADEDQIR---------AEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIeaSEK 1299
Cdd:TIGR02169  733 EKLKERLEELEEDLSSLEQEIENVKSelkeleariEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEV--SRI 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1300 SEQAALNAAKEKALQQLREQLEGERKEAVATLEkehsaelerlcssleakhrevvsSLQKKIQEAQQKEEAqLQKCLGQV 1379
Cdd:TIGR02169  811 EARLREIEQKLNRLTLEKEYLEKEIQELQEQRI-----------------------DLKEQIKSIEKEIEN-LNGKKEEL 866

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1380 EHRVHQKSYHVAGYEHELSSLLREKRqevegEHERRLDKMKEEHQQvmAKAREQYEAEERKQRAELLGHLTGELERLQRA 1459
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERD-----ELEAQLRELERKIEE--LEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462523724 1460 HERELETVRQEQhkRLEDLRRRHREQERKLQDLElDLETRA----KDVKARLALLEVQEETARREKQQLLD 1526
Cdd:TIGR02169  940 KGEDEEIPEEEL--SLEDVQAELQRVEEEIRALE-PVNMLAiqeyEEVLKRLDELKEKRAKLEEERKAILE 1007

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1237-1551

2.20e-09

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 62.78 E-value: 2.20e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1237 WLRAQVQSSTQADEDQIRAeQEASLQKLREELESQQKAERASLEQKNrQMLEQLKEEIEASEKSEQAALnaaKEKALQQL 1316
Cdd:TIGR02169  226 YELLKEKEALERQKEAIER-QLASLEEELEKLTEEISELEKRLEEIE-QLLEELNKKIKDLGEEEQLRV---KEKIGELE 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1317 REQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEaQQKEEAQLQKCLGQVEHRVHQKSYHVAgyehE 1396
Cdd:TIGR02169  301 AEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEE-ERKRRDKLTEEYAELKEELEDLRAELE----E 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1397 LSSLLREKRQEVEgEHERRLDKMKEEHQQVMakaREQYEAEERKQRAEL-LGHLTGELERLQRAHeRELETvrqeqhkRL 1475
Cdd:TIGR02169  376 VDKEFAETRDELK-DYREKLEKLKREINELK---RELDRLQEELQRLSEeLADLNAAIAGIEAKI-NELEE-------EK 443

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462523724 1476 EDLRRRHREQERKLQDLELDLEtrakdvKARLALLEVQEETARREKQqlldvQRQVALKSEEATATHQQLEEAQKE 1551
Cdd:TIGR02169  444 EDKALEIKKQEWKLEQLAADLS------KYEQELYDLKEEYDRVEKE-----LSKLQRELAEAEAQARASEERVRG 508

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1154-1770

3.06e-09

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 62.39 E-value: 3.06e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1154 EAALKAMEEAVAQVLEQ--DQRHLLESKQEKMQQLREKLCQEEEEEILRLhQQKEQSLSSLRERLQKAIEEEEarmreee 1231
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEisELEKRLEEIEQLLEELNKKIKDLGEEEQLRV-KEKIGELEAEIASLERSIAEKE------- 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1232 sQRLSWLRAQVQsstQADEDqiRAEQEASLQKLREELESQQKaERASLE---QKNRQMLEQLKEEIEASEKSEQAA---L 1305
Cdd:TIGR02169  315 -RELEDAEERLA---KLEAE--IDKLLAEIEELEREIEEERK-RRDKLTeeyAELKEELEDLRAELEEVDKEFAETrdeL 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1306 NAAKEK--ALQQLREQLEGERKEAVATLEKEHS--AELERLCSSLEAKHREVVS---SLQKKIQEAQQKEEaQLQKCLGQ 1378
Cdd:TIGR02169  388 KDYREKleKLKREINELKRELDRLQEELQRLSEelADLNAAIAGIEAKINELEEekeDKALEIKKQEWKLE-QLAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1379 VEHRVHQKSYHVAGYEHELSSLLRE-------KRQEVEGEHERR-------------------LDKMKEEHQ---QVMAK 1429
Cdd:TIGR02169  467 YEQELYDLKEEYDRVEKELSKLQRElaeaeaqARASEERVRGGRaveevlkasiqgvhgtvaqLGSVGERYAtaiEVAAG 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1430 AREQY---EAEERKQRA-ELL-----GHLTGELERLQRAHERELETVRQ-----------EQHKRLE------------- 1476
Cdd:TIGR02169  547 NRLNNvvvEDDAVAKEAiELLkrrkaGRATFLPLNKMRDERRDLSILSEdgvigfavdlvEFDPKYEpafkyvfgdtlvv 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1477 ---DLRRRHREQERkLQDLELDL-----------------ETRAKDVKARLALLEVQEETARREKQQLLD----VQRQVA 1532
Cdd:TIGR02169  627 ediEAARRLMGKYR-MVTLEGELfeksgamtggsraprggILFSRSEPAELQRLRERLEGLKRELSSLQSelrrIENRLD 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1533 LKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVt 1612
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL- 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1613 veENNASPHFEPDL--HIEDLRKSLGTNQtkEVSSSLSQSKEDLYLDSLSshnvwhllsaegvaLRSAKEFLVQQTRSMR 1690
Cdd:TIGR02169  785 --EARLSHSRIPEIqaELSKLEEEVSRIE--ARLREIEQKLNRLTLEKEY--------------LEKEIQELQEQRIDLK 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1691 RRQTALKAAQQHWRHELAS-AQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEA 1769
Cdd:TIGR02169  847 EQIKSIEKEIENLNGKKEElEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926


                   .
gi 2462523724 1770 S 1770
Cdd:TIGR02169  927 E 927

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

1157-1776

8.34e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 61.22 E-value: 8.34e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1157 LKAMEEAVAQVLE-QDQRHLLESKQEKMQQLREKLCQEEEE----------EILRLHQQKEQSLSSLRERLQKAIEEEEA 1225
Cdd:TIGR00606  254 LKEIEHNLSKIMKlDNEIKALKSRKKQMEKDNSELELKMEKvfqgtdeqlnDLYHNHQRTVREKERELVDCQRELEKLNK 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1226 RMREEESQRLSWLRAQVQSSTQAD--EDQIRAEQEASLQ-KLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQ 1302
Cdd:TIGR00606  334 ERRLLNQEKTELLVEQGRLQLQADrhQEHIRARDSLIQSlATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1303 AALNAAKEKALQQLREQLEGERKEAVATLEKEhSAELERLCSSLeakhREVVSSLQK---------KIQEAQQKEEAQLQ 1373
Cdd:TIGR00606  414 CADLQSKERLKQEQADEIRDEKKGLGRTIELK-KEILEKKQEEL----KFVIKELQQlegssdrilELDQELRKAERELS 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1374 KClgQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHErrLDKMKEEHQQVMAKAREQYEAEER------KQRAELLG 1447
Cdd:TIGR00606  489 KA--EKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQ--LNHHTTTRTQMEMLTKDKMDKDEQirkiksRHSDELTS 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1448 HL-----TGELERLQRAHERELETVR------QEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARlallEVQEET 1516
Cdd:TIGR00606  565 LLgyfpnKKQLEDWLHSKSKEINQTRdrlaklNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS----QDEESD 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1517 ARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSS 1596
Cdd:TIGR00606  641 LERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKK 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1597 LEAEaqkKQHLLREVTVEENnasphfEPDLHIEDLRKSlgTNQTKEVSSSLSQSKEDLYLDSlsshnvwHLLSAEGVALR 1676
Cdd:TIGR00606  721 KEKR---RDEMLGLAPGRQS------IIDLKEKEIPEL--RNKLQKVNRDIQRLKNDIEEQE-------TLLGTIMPEEE 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1677 SAKEFLVQQTrSMRRRQTALKAAQQHWRHELASAQEVAKDppgiKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEE 1756
Cdd:TIGR00606  783 SAKVCLTDVT-IMERFQMELKDVERKIAQQAAKLQGSDLD----RTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQE 857

                          650       660
                   ....*....|....*....|
gi 2462523724 1757 KLNQLESSLWEEASDEGTLG 1776
Cdd:TIGR00606  858 QIQHLKSKTNELKSEKLQIG 877

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1460-1777

9.20e-09

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.84 E-value: 9.20e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1460 HERELETVR-----QEQHKRLEDLRRrhrEQERKLQDLEL---------DLETRAKDVKARLALLEVQEETARRE--KQQ 1523
Cdd:TIGR02168  171 KERRKETERklertRENLDRLEDILN---ELERQLKSLERqaekaerykELKAELRELELALLVLRLEELREELEelQEE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1524 LLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAE--- 1600
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQlee 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1601 -AQKKQHLLREVT-VEENNASphFEPDlhIEDLRKSLGT-NQTKEVSSSLSQSKEDLYLDslsshnvwhlLSAEGVALRS 1677
Cdd:TIGR02168  328 lESKLDELAEELAeLEEKLEE--LKEE--LESLEAELEElEAELEELESRLEELEEQLET----------LRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1678 AKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPpgikALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEK 1757
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA----ELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          330       340
                   ....*....|....*....|
gi 2462523724 1758 LNQLESSLWEEASDEGTLGG 1777
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQA 489

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

1022-1580

1.14e-08

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 60.37 E-value: 1.14e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1022 QSKQSKG----LEERYHRLSPPLPheERAQSPPRSLAT-EEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQaps 1096
Cdd:TIGR00618  188 KKKSLHGkaelLTLRSQLLTLCTP--CMPDTYHERKQVlEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLL--- 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1097 ppaacekgKEQHSQAEELGPGQEEAEDPEEKVAVSP-TPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHL 1175
Cdd:TIGR00618  263 --------KQLRARIEELRAQEAVLEETQERINRARkAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHV 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1176 -----LESKQEKMQQL-----------------REKLCQEEEEE--ILRLHQQKE------QSLSSLRERLQK------- 1218
Cdd:TIGR00618  335 kqqssIEEQRRLLQTLhsqeihirdahevatsiREISCQQHTLTqhIHTLQQQKTtltqklQSLCKELDILQReqatidt 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1219 --------AIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELE--------SQQKAERASLEQK 1282
Cdd:TIGR00618  415 rtsafrdlQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQqlqtkeqiHLQETRKKAVVLA 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1283 NRQMLEQLKEEIEASEKSEQAALNAAKE-KALQQLREQLEGERK---EAVATLEKEHSAELERLcSSLEAKHREVVSSLQ 1358
Cdd:TIGR00618  495 RLLELQEEPCPLCGSCIHPNPARQDIDNpGPLTRRMQRGEQTYAqleTSEEDVYHQLTSERKQR-ASLKEQMQEIQQSFS 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1359 KKIQEAQQ-KEEAQ-LQKCLGQVEHRVHQKSyhvagyEHELSSLLREKRQEVEGEHERRL--------DKMKEEHQQVMA 1428
Cdd:TIGR00618  574 ILTQCDNRsKEDIPnLQNITVRLQDLTEKLS------EAEDMLACEQHALLRKLQPEQDLqdvrlhlqQCSQELALKLTA 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1429 KAREQYEAEERKQRAELLGHLTGELERLQR--AHERELE-----------------TVRQEQHKRLEDLRRRHREQERKL 1489
Cdd:TIGR00618  648 LHALQLTLTQERVREHALSIRVLPKELLASrqLALQKMQsekeqltywkemlaqcqTLLRELETHIEEYDREFNEIENAS 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1490 QDLELDLETRAKdvkarlALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQkehtHLLQSNQQLREILDEL 1569
Cdd:TIGR00618  728 SSLGSDLAARED------ALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELS----HLAAEIQFFNRLREED 797

                          650
                   ....*....|.
gi 2462523724 1570 QARKLKLESQV 1580
Cdd:TIGR00618  798 THLLKTLEAEI 808

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1154-1619

1.21e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 60.57 E-value: 1.21e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1154 EAALKAMEEAVAQVLEQDQRHLLESKQekmqqLREKLCQEEEEeiLRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQ 1233
Cdd:pfam01576  130 EAKIKKLEEDILLLEDQNSKLSKERKL-----LEERISEFTSN--LAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1234 RLSWLRAQVQSSTQADE--DQIR------AEQEASLQKLREELES------QQKAERASLEQKNRQMLEQLKEEIEASEk 1299
Cdd:pfam01576  203 RQELEKAKRKLEGESTDlqEQIAelqaqiAELRAQLAKKEEELQAalarleEETAQKNNALKKIRELEAQISELQEDLE- 281

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1300 SEQAALNAAkEKALQQLREQLEGERKEAVATL-----EKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK 1374
Cdd:pfam01576  282 SERAARNKA-EKQRRDLGEELEALKTELEDTLdttaaQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1375 CLGQVEHRVHQKS---YHVAGYEHELSSLLREKR--QEVEGEHERRLDKMKEEHQQVMAKAREQyeAEERKQRAELLGHL 1449
Cdd:pfam01576  361 LTEQLEQAKRNKAnleKAKQALESENAELQAELRtlQQAKQDSEHKRKKLEGQLQELQARLSES--ERQRAELAEKLSKL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1450 TGELERLQRAHErELETVRQEQHKRLEDLrrrhreqERKLQDLE--LDLETRAK------------DVKARLALLEVQEE 1515
Cdd:pfam01576  439 QSELESVSSLLN-EAEGKNIKLSKDVSSL-------ESQLQDTQelLQEETRQKlnlstrlrqledERNSLQEQLEEEEE 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1516 TARREKQQLLDVQRQVA---LKSEEATATHQQLEEAQKEHTHLLQS-NQQLRE---ILDELQARKLKLESQVDLLQAQSQ 1588
Cdd:pfam01576  511 AKRNVERQLSTLQAQLSdmkKKLEEDAGTLEALEEGKKRLQRELEAlTQQLEEkaaAYDKLEKTKNRLQQELDDLLVDLD 590

                          490       500       510
                   ....*....|....*....|....*....|.
gi 2462523724 1589 QLQKHFSSLEaeaqKKQHLLREVTVEENNAS 1619
Cdd:pfam01576  591 HQRQLVSNLE----KKQKKFDQMLAEEKAIS 617

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1302-1540

1.83e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.62 E-value: 1.83e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1302 QAALNAAKEKALQQLREQLEgERKEAVATLEKEHSAELERLcssleAKHREVVSSLQKKIQEAQQkEEAQLQKCLGQVEH 1381
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIA-ELEKELAALKKEEKALLKQL-----AALERRIAALARRIRALEQ-ELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1382 RVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRahe 1461
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA--- 167

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462523724 1462 rELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATA 1540
Cdd:COG4942    168 -ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245

PRK02224

DNA double-strand break repair Rad50 ATPase;

1275-1772

2.24e-08

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 59.67 E-value: 2.24e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1275 ERAS--------LEQKNRQMLEQLKEEIEASEKSE-QAALNAAkEKALQQLREQL---EGERKEAVATLEK------EHS 1336
Cdd:PRK02224   169 ERASdarlgverVLSDQRGSLDQLKAQIEEKEEKDlHERLNGL-ESELAELDEEIeryEEQREQARETRDEadevleEHE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1337 AELERLcSSLEAKHREvvssLQKKIQEAQQKEEAqlqkclgqVEHRVHQKSYHVAGYEHELSSLLREkrQEVEGEHERRL 1416
Cdd:PRK02224   248 ERREEL-ETLEAEIED----LRETIAETEREREE--------LAEEVRDLRERLEELEEERDDLLAE--AGLDDADAEAV 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1417 DKMKEEHQQVMAKAREQYEaEERKQRAELLGHLTGELERLQRAHER--ELETVRQEQHKRLEDLRRRHREQERKLQDLEL 1494
Cdd:PRK02224   313 EARREELEDRDEELRDRLE-ECRVAAQAHNEEAESLREDADDLEERaeELREEAAELESELEEAREAVEDRREEIEELEE 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1495 DLEtrakDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQS------NQQLR----- 1563
Cdd:PRK02224   392 EIE----ELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecGQPVEgsphv 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1564 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLE--AEAQKKQHLLREV--TVEEnnasphfepdlHIEDLRKSLgtNQ 1639
Cdd:PRK02224   468 ETIEEDRERVEELEAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERreDLEE-----------LIAERRETI--EE 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1640 TKEVSSSLSQSKEDlyldslsshnvwhlLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPG 1719
Cdd:PRK02224   535 KRERAEELRERAAE--------------LEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAA 600

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462523724 1720 IKALEDMRKNLEKETRHLDEMKSAMRKghnLLKKKEEKLNQLESSLWEEASDE 1772
Cdd:PRK02224   601 IADAEDEIERLREKREALAELNDERRE---RLAEKRERKRELEAEFDEARIEE 650

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1392-1740

2.50e-08

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 59.31 E-value: 2.50e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1392 GYEHELSSLLREKRqEVEGEHERRLDKMKEEHQQV--MAKAREQYEAEERKQRAELlghltGELERLQRAHERELETVRQ 1469
Cdd:TIGR02169  685 GLKRELSSLQSELR-RIENRLDELSQELSDASRKIgeIEKEIEQLEQEEEKLKERL-----EELEEDLSSLEQEIENVKS 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1470 EqhkrLEDLRRRHREQERKLQDLELDLEtrakDVKARLALLEVQEETARREKQQLlDVQRQVAlkseeatathqQLEEAQ 1549
Cdd:TIGR02169  759 E----LKELEARIEELEEDLHKLEEALN----DLEARLSHSRIPEIQAELSKLEE-EVSRIEA-----------RLREIE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1550 KEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEennasphfepdlhIE 1629
Cdd:TIGR02169  819 QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR-------------LG 885

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1630 DLRKslgtnQTKEVSSSLSQSKEdlyldslsshnvwhllsaegvALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELAS 1709
Cdd:TIGR02169  886 DLKK-----ERDELEAQLRELER---------------------KIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939

                          330       340       350
                   ....*....|....*....|....*....|.
gi 2462523724 1710 AQEVAKDPPGIKALEDMRKNLEKETRHLDEM 1740
Cdd:TIGR02169  940 KGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970

PRK02224

DNA double-strand break repair Rad50 ATPase;

1234-1579

2.74e-08

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 59.28 E-value: 2.74e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1234 RLSWLRAQVQSSTQADEDQIRAEQEASLQKLREEL---ESQQKAERASLEQKN---------RQMLEQLKEEIEASEKSE 1301
Cdd:PRK02224   188 SLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIeryEEQREQARETRDEADevleeheerREELETLEAEIEDLRETI 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1302 qaalnAAKEKALQQLREQLEgERKEAVATLEKEHSAELERlcSSLEAKHREVVSSLqkkiQEAQQKEEAQLQKCLGQVEH 1381
Cdd:PRK02224   268 -----AETEREREELAEEVR-DLRERLEELEEERDDLLAE--AGLDDADAEAVEAR----REELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1382 RVHQKSYHVAGYEHELSSL------LREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEER-----KQRAELLGHLT 1450
Cdd:PRK02224   336 AAQAHNEEAESLREDADDLeeraeeLREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdapVDLGNAEDFLE 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1451 GELERLQRAHER--ELETVRQEQHKRLEDLRR------------------------RHREQERKLQDLELDLETRAKDVK 1504
Cdd:PRK02224   416 ELREERDELREReaELEATLRTARERVEEAEAlleagkcpecgqpvegsphvetieEDRERVEELEAELEDLEEEVEEVE 495

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462523724 1505 ARLALLEVQEETARR---EKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREildelQARKLKLESQ 1579
Cdd:PRK02224   496 ERLERAEDLVEAEDRierLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKRE-----AAAEAEEEAE 568

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1150-1768

2.87e-08

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 59.21 E-value: 2.87e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1150 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMRE 1229
Cdd:pfam02463  287 ELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQE 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1230 EESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERAS--LEQKNRQMLEQLKEEIEASEKSEQAALNA 1307
Cdd:pfam02463  367 KLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARqlEDLLKEEKKEELEILEEEEESIELKQGKL 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1308 AKEKALQQLRE------QLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK---CLGQ 1378
Cdd:pfam02463  447 TEEKEELEKQElkllkdELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGvggRIIS 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1379 VEHRVHQKSYHVAGYEHELSSLL-----REKRQEVEGEHERR---------------LDKMKEEHQQVMAKAREQYEAEE 1438
Cdd:pfam02463  527 AHGRLGDLGVAVENYKVAISTAVivevsATADEVEERQKLVRaltelplgarklrllIPKLKLPLKSIAVLEIDPILNLA 606

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1439 RKQRAELLGHLTGELERLQRAHERE-LETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEetA 1517
Cdd:pfam02463  607 QLDKATLEADEDDKRAKVVEGILKDtELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQE--K 684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1518 RREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQvDLLQAQSQQLQKHFSSL 1597
Cdd:pfam02463  685 AESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKID-EEEEEEEKSRLKKEEKE 763

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1598 EAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLG-TNQTKEVSSSLSQSKEDLYLDSLSSH---NVWHLLSAEGV 1673
Cdd:pfam02463  764 EEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEElRALEEELKEEAELLEEEQLLIEQEEKikeEELEELALELK 843

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1674 ALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKK 1753
Cdd:pfam02463  844 EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          650
                   ....*....|....*
gi 2462523724 1754 KEEKLNQLESSLWEE 1768
Cdd:pfam02463  924 KEEAEILLKYEEEPE 938

PRK03918

DNA double-strand break repair ATPase Rad50;

1255-1514

4.15e-08

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.54 E-value: 4.15e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1255 AEQEASLQKLREELESQQKA-ERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKaLQQLREQLEGERKEaVATLEK 1333
Cdd:PRK03918   469 KEIEEKERKLRKELRELEKVlKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEE-YEKLKEKLIKLKGE-IKSLKK 546

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1334 EHS--AELERLCSSLEAKHREV---VSSLQKKIQEAQQKEEAQLQKCLGQVEhRVHQKSYHVAGYEHELSSLLREKRQEv 1408
Cdd:PRK03918   547 ELEklEELKKKLAELEKKLDELeeeLAELLKELEELGFESVEELEERLKELE-PFYNEYLELKDAEKELEREEKELKKL- 624

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1409 egehERRLDKMKEEHQQVMAKARE----------QYEAEERKQRAELLGHLTGELERLqRAHERELETVRQEQHKRLEDL 1478
Cdd:PRK03918   625 ----EEELDKAFEELAETEKRLEElrkeleelekKYSEEEYEELREEYLELSRELAGL-RAELEELEKRREEIKKTLEKL 699

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 2462523724 1479 RRRHREQERKLQDLEL---------DLETRAKDVKARL---ALLEVQE 1514
Cdd:PRK03918   700 KEELEEREKAKKELEKlekalerveELREKVKKYKALLkerALSKVGE 747

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1412-1581

4.26e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.24 E-value: 4.26e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1412 HERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELEtvRQEQHKRLEDLRRRHREQERKLQD 1491
Cdd:COG4717     66 PELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE--KLEKLLQLLPLYQELEALEAELAE 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1492 LEldleTRAKDVKARLALLEVQEETARREKQQLLDVQRQVA-LKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQ 1570
Cdd:COG4717    144 LP----ERLEELEERLEELRELEEELEELEAELAELQEELEeLLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219

                          170
                   ....*....|.
gi 2462523724 1571 ARKLKLESQVD 1581
Cdd:COG4717    220 EELEELEEELE 230

PRK03918

DNA double-strand break repair ATPase Rad50;

1352-1768

4.75e-08

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.54 E-value: 4.75e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1352 EVVSSLQKKIQEAQQ--KEEAQLQKCLGQVEHRVHQKSYHVagyeHELSSLLREKRQEVEGEHER--RLDKMKEEhqqvM 1427
Cdd:PRK03918   169 EVIKEIKRRIERLEKfiKRTENIEELIKEKEKELEEVLREI----NEISSELPELREELEKLEKEvkELEELKEE----I 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1428 AKAREQYEAEERKQRA--ELLGHLTGELERLqRAHERELETVRQE---------QHKRLEDLRRRHREQERKLQDLELDL 1496
Cdd:PRK03918   241 EELEKELESLEGSKRKleEKIRELEERIEEL-KKEIEELEEKVKElkelkekaeEYIKLSEFYEEYLDELREIEKRLSRL 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1497 ETRAKDVKARLALLEVQEETARREKQQLLDVQRQV------ALKSEEATATHQQLEEAQKEHTHLlqSNQQLREILDELQ 1570
Cdd:PRK03918   320 EEEINGIEERIKELEEKEERLEELKKKLKELEKRLeeleerHELYEEAKAKKEELERLKKRLTGL--TPEKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1571 ARKLKLESQVDLLQAQSQQLQKHFSSLEA------EAQKKQHLL-REVTveennasphfepdlhiEDLRKSLGTNQTKEV 1643
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKaieelkKAKGKCPVCgRELT----------------EEHRKELLEEYTAEL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1644 SSSLSQSKEdlyLDSLSSHnvwhlLSAEGVALRSakeFLVQQTRSMRRRQTA--LKAAQQHWR-HELASAQEVAKDPPGI 1720
Cdd:PRK03918   462 KRIEKELKE---IEEKERK-----LRKELRELEK---VLKKESELIKLKELAeqLKELEEKLKkYNLEELEKKAEEYEKL 530

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462523724 1721 K----ALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEE 1768
Cdd:PRK03918   531 KekliKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEEL 582

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1260-1518

5.15e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 58.39 E-value: 5.15e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1260 SLQKLREELES-QQKAERAsleQKNRQMLEQLKEEIE--ASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHS 1336
Cdd:COG4913    229 ALVEHFDDLERaHEALEDA---REQIELLEPIRELAEryAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1337 AELERL--CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLlrekrQEVEGEHER 1414
Cdd:COG4913    306 RLEAELerLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAAL-----GLPLPASAE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1415 RLDKMKEEHQQvmakAREQYEAEERKQRAELlghltGELERLQRAHERELETVRQEqhkrLEDLRRRHREQERKLQDLEL 1494
Cdd:COG4913    381 EFAALRAEAAA----LLEALEEELEALEEAL-----AEAEAALRDLRRELRELEAE----IASLERRKSNIPARLLALRD 447

                          250       260
                   ....*....|....*....|....*...
gi 2462523724 1495 DLETRAKDVKARLA----LLEVQEETAR 1518
Cdd:COG4913    448 ALAEALGLDEAELPfvgeLIEVRPEEER 475

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1167-1537

5.24e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 58.39 E-value: 5.24e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1167 VLEQDQRHLLESKQEKMQQLREKLcQEEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARMREEESQR-LSWLRAQVQSS 1245
Cdd:COG4913    603 VLGFDNRAKLAALEAELAELEEEL-AEAEERLEALEAELDA-LQERREALQRLAEYSWDEIDVASAEReIAELEAELERL 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1246 TQADED-----QIRAEQEASLQKLREELEsQQKAERASLEQKnrqmLEQLKEEIEASekseQAALNAAKEKALQQLREQL 1320
Cdd:COG4913    681 DASSDDlaaleEQLEELEAELEELEEELD-ELKGEIGRLEKE----LEQAEEELDEL----QDRLEAAEDLARLELRALL 751

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1321 EGERKEA-VATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgqvEHRVHQKSYHvaGYEHELSS 1399
Cdd:COG4913    752 EERFAAAlGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETA------DLDADLESLP--EYLALLDR 823

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1400 LLREKRQEVEGEHERRLDKMKEEH----QQVMAKAREqyEAEERkqraelLGHLTGELERLQRAHERELE-TVRQEQHKR 1474
Cdd:COG4913    824 LEEDGLPEYEERFKELLNENSIEFvadlLSKLRRAIR--EIKER------IDPLNDSLKRIPFGPGRYLRlEARPRPDPE 895

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462523724 1475 LEDLRRRHREQERKLQDLELDL-ETRAKDVKARLALLEVQE-ETARREKQQLLDVQRQVALKSEE 1537
Cdd:COG4913    896 VREFRQELRAVTSGASLFDEELsEARFAALKRLIERLRSEEeESDRRWRARVLDVRNHLEFDAEE 960

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

1258-1492

5.30e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 58.43 E-value: 5.30e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1258 EASLQKLRE---ELESQQKAERASlEQKNRQMLEQLKEEIEASEK-SEQAALNAAKEKA--LQQLREQLEgERKEAVATL 1331
Cdd:COG3096    835 EAELAALRQrrsELERELAQHRAQ-EQQLRQQLDQLKEQLQLLNKlLPQANLLADETLAdrLEELREELD-AAQEAQAFI 912

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1332 EK--EHSAELERLCSSLEAKhREVVSSLQKKIQEAQQKEEAQLQKC--LGQVEHRVHQKSYHVA----GYEHELSSLLRE 1403
Cdd:COG3096    913 QQhgKALAQLEPLVAVLQSD-PEQFEQLQADYLQAKEQQRRLKQQIfaLSEVVQRRPHFSYEDAvgllGENSDLNEKLRA 991

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1404 KRQEVEGEHERRLDKMK------EEHQQVMAKAREQYEAeerkqRAELLGHLTGELERL---------QRAHER------ 1462
Cdd:COG3096    992 RLEQAEEARREAREQLRqaqaqySQYNQVLASLKSSRDA-----KQQTLQELEQELEELgvqadaeaeERARIRrdelhe 1066

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2462523724 1463 ----------ELETVRQEQHKRLEDLRRRHREQERKLQDL 1492
Cdd:COG3096   1067 elsqnrsrrsQLEKQLTRCEAEMDSLQKRLRKAERDYKQE 1106

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1357-1764

5.46e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.86 E-value: 5.46e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1357 LQKKIQEAQQKEE--AQLQKCLGQVEHRVHQKSYHVAGYEHELSSL-----LREKRQEVEgEHERRLDKMKEEHQQVMAK 1429
Cdd:COG4717     76 LEEELKEAEEKEEeyAELQEELEELEEELEELEAELEELREELEKLekllqLLPLYQELE-ALEAELAELPERLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1430 AREQYEAEERKQRAEllghltGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLET---RAKDVKAR 1506
Cdd:COG4717    155 LEELRELEEELEELE------AELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEaqeELEELEEE 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1507 LALLEVQEETArREKQQLLDVQRQVALKSE--EATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQvdllq 1584
Cdd:COG4717    229 LEQLENELEAA-ALEERLKEARLLLLIAAAllALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGK----- 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1585 aqsqqlqkhfSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGT-NQTKEVSSSLSQSKEDLYLDSLSSHN 1663
Cdd:COG4717    303 ----------EAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRiEELQELLREAEELEEELQLEELEQEI 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1664 VwHLLSAEGVALRSAKEFLVQQTrsmrRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA 1743
Cdd:COG4717    373 A-ALLAEAGVEDEEELRAALEQA----EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEE 447

                          410       420
                   ....*....|....*....|.
gi 2462523724 1744 MRKGHNLLKKKEEKLNQLESS 1764
Cdd:COG4717    448 LEELREELAELEAELEQLEED 468

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1235-1470

7.91e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 56.70 E-value: 7.91e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1235 LSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQknrqmLEQLKEEIEASEK------SEQAALNA- 1307
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ-----LAALERRIAALARriraleQELAALEAe 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1308 -----AKEKALQQLREQLEGERKEAVATLEKEHSA-ELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEH 1381
Cdd:COG4942     85 laeleKEIAELRAELEAQKEELAELLRALYRLGRQpPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1382 RVHQKSYHVAgyehELSSLLREKRQEvegehERRLDKMKEEHQQVMAKAREQYEAEErkQRAELLGHLTGELERLQRAHE 1461
Cdd:COG4942    165 LRAELEAERA----ELEALLAELEEE-----RAALEALKAERQKLLARLEKELAELA--AELAELQQEAEELEALIARLE 233


                   ....*....
gi 2462523724 1462 RELETVRQE 1470
Cdd:COG4942    234 AEAAAAAER 242

HEC1

COG5185

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...

1157-1535

8.36e-08

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 57.27 E-value: 8.36e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1157 LKAMEEAVAQVLEQDQrhllESKQEKMQQLREKlcqeeeeeILRLHQQKEQ---SLSSLRERLQKAIeeeearmreeesQ 1233
Cdd:COG5185    248 LAQTSDKLEKLVEQNT----DLRLEKLGENAES--------SKRLNENANNlikQFENTKEKIAEYT------------K 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1234 RLSWLRAQVQSSTQADedqiRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKE----------EIEASEKSEQA 1303
Cdd:COG5185    304 SIDIKKATESLEEQLA----AAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAikeeienivgEVELSKSSEEL 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1304 -----ALNAAKEKALQQLREQlEGERKEAVATLE---KEHSAELERLCSSLEAKHREVvsslqkkiqEAQQKEEAQLQKC 1375
Cdd:COG5185    380 dsfkdTIESTKESLDEIPQNQ-RGYAQEILATLEdtlKAADRQIEELQRQIEQATSSN---------EEVSKLLNELISE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1376 LGQVEHRVhqksyhvagyEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREqyeaeerkqraellghLTGELER 1455
Cdd:COG5185    450 LNKVMREA----------DEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVST----------------LKATLEK 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1456 LQRAHERELETVRQEQHKRLEDLRRRHREQErklQDLELDLETRAKDVKARLALLE--VQEETARREKQQLLDVQRQVAL 1533
Cdd:COG5185    504 LRAKLERQLEGVRSKLDQVAESLKDFMRARG---YAHILALENLIPASELIQASNAktDGQAANLRTAVIDELTQYLSTI 580


                   ..
gi 2462523724 1534 KS 1535
Cdd:COG5185    581 ES 582

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

1044-1368

8.52e-08

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 57.46 E-value: 8.52e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1044 ERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDsaaslslqlslqreQAPSPPAACEKGKEQHSQAEELGPgQEEAED 1123
Cdd:pfam09731   76 TGESKEPKEEKKQVKIPRQSGVSSEVAEEEKEATK--------------DAAEAKAQLPKSEQEKEKALEEVL-KEAISK 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1124 PEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLeqdqrHLLESKQEKMQQLREKLCQEEEEEILRLHQ 1203
Cdd:pfam09731  141 AESATAVAKEAKDDAIQAVKAHTDSLKEASDTAEISREKATDSAL-----QKAEALAEKLKEVINLAKQSEEEAAPPLLD 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1204 QKEQSLSSLRERLQKAIEEEEArmreeeSQRLSWLRAQVQSSTqADEDQIRAEQEAS----------------------- 1260
Cdd:pfam09731  216 AAPETPPKLPEHLDNVEEKVEK------AQSLAKLVDQYKELV-ASERIVFQQELVSifpdiipvlkednllsnddlnsl 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1261 -------LQKLREELESQQKAERASLEQKnrqmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEK 1333
Cdd:pfam09731  289 iahahreIDQLSKKLAELKKREEKHIERA----LEKQKEELDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEE 364

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 2462523724 1334 EHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKE 1368
Cdd:pfam09731  365 KLRTELERQAEAHEEHLKDVLVEQEIELQREFLQD 399

PRK12704

phosphodiesterase; Provisional

1152-1340

1.93e-07

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 55.94 E-value: 1.93e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1152 LSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKlcqeeeeeILRLHQQKEQSLSSLRERLQkaieeeearmreee 1231
Cdd:PRK12704    28 IAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEE--------IHKLRNEFEKELRERRNELQ-------------- 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1232 sqrlswlraQVQSSTQADEDQIRAEQEaSLQKLREELESQQKaeraSLEQKNRQmLEQLKEEIEASEKSEQAAL----NA 1307
Cdd:PRK12704    86 ---------KLEKRLLQKEENLDRKLE-LLEKREEELEKKEK----ELEQKQQE-LEKKEEELEELIEEQLQELerisGL 150

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2462523724 1308 AKEKALQQLREQLEGE-RKEAVATL-EKEHSAELE 1340
Cdd:PRK12704   151 TAEEAKEILLEKVEEEaRHEAAVLIkEIEEEAKEE 185

PspA_IM30

pfam04012

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ...

1238-1377

2.03e-07

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.

Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 53.92 E-value: 2.03e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1238 LRAQVQSSTQADED------QIRAEQEASLQKLREELEsQQKAERASLEQKnrqmLEQLKEEIEASEKSEQAALNAAKE- 1310
Cdd:pfam04012    9 VRANIHEGLDKAEDpekmleQAIRDMQSELVKARQALA-QTIARQKQLERR----LEQQTEQAKKLEEKAQAALTKGNEe 83

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462523724 1311 ---KALQQlREQLEG--ERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQK-KIQEAQQKEEAQLQKCLG 1377
Cdd:pfam04012   84 larEALAE-KKSLEKqaEALETQLAQQRSAVEQLRKQLAALETKIQQLKAKKNLlKARLKAAKAQEAVQTSLG 155

PTZ00121

MAEBL; Provisional

1291-1769

2.74e-07

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 56.30 E-value: 2.74e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1291 KEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAElerlcsslEAKHREVVsslqKKIQEAQQKEEA 1370
Cdd:PTZ00121  1084 KEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAE--------EARKAEDA----RKAEEARKAEDA 1151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1371 QLQKCLGQVEhrvhqksyhvagyEHELSSLLREKRQEVEGEHERRLDKMKEEHQqvMAKAREQYEAEERKQRAELLghlt 1450
Cdd:PTZ00121  1152 KRVEIARKAE-------------DARKAEEARKAEDAKKAEAARKAEEVRKAEE--LRKAEDARKAEAARKAEEER---- 1212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1451 gELERLQRAHE-RELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQR 1529
Cdd:PTZ00121  1213 -KAEEARKAEDaKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKK 1291

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1530 QVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLR 1609
Cdd:PTZ00121  1292 ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK 1371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1610 EVTVEENNASphfEPDLHIEDLRKSlgtNQTKEVSSSLSQSKEDLYLDSLSSHNVwHLLSAEGVALRSAKEfLVQQTRSM 1689
Cdd:PTZ00121  1372 KKEEAKKKAD---AAKKKAEEKKKA---DEAKKKAEEDKKKADELKKAAAAKKKA-DEAKKKAEEKKKADE-AKKKAEEA 1443

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1690 RRRQTALKAAQqhwrhELASAQEVAKDPPGIKALEDMRKNLEkETRHLDEMK----SAMRKGHNLLKKKEEKLNQLESSL 1765
Cdd:PTZ00121  1444 KKADEAKKKAE-----EAKKAEEAKKKAEEAKKADEAKKKAE-EAKKADEAKkkaeEAKKKADEAKKAAEAKKKADEAKK 1517


                   ....
gi 2462523724 1766 WEEA 1769
Cdd:PTZ00121  1518 AEEA 1521

Mplasa_alph_rch

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

1168-1580

2.74e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 55.80 E-value: 2.74e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1168 LEQDQRHLLESKQEKMQQLREKlcqeeEEEILRLHQQKEQSLSSL---RERLQKAIEEEEARmreeeSQRLSWLRAQVQS 1244
Cdd:TIGR04523  223 LKKQNNQLKDNIEKKQQEINEK-----TTEISNTQTQLNQLKDEQnkiKKQLSEKQKELEQN-----NKKIKELEKQLNQ 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1245 STQADEDQIRAEQEASLQKLREELESQQKAERASLEQ--KNRQMLEQLKEEIEASEKSEQAalnaaKEKALQQLREQLEg 1322
Cdd:TIGR04523  293 LKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQisQNNKIISQLNEQISQLKKELTN-----SESENSEKQRELE- 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1323 ERKEAVATLEKEHSAELERLcSSLEAKHREVVSSLQKKIQEAQQKEE--AQLQKCLGQVEHRVHQKSYHVAGYEHELSSL 1400
Cdd:TIGR04523  367 EKQNEIEKLKKENQSYKQEI-KNLESQINDLESKIQNQEKLNQQKDEqiKKLQQEKELLEKEIERLKETIIKNNSEIKDL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1401 lREKRQEVEGEHERrLDKMKEEHQQVMAKAREQYEAEER--KQRAELLGHLTGELERLQRaHERELE------TVRQEQH 1472
Cdd:TIGR04523  446 -TNQDSVKELIIKN-LDNTRESLETQLKVLSRSINKIKQnlEQKQKELKSKEKELKKLNE-EKKELEekvkdlTKKISSL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1473 K-RLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQE---------------ETARREKQQLL--------DVQ 1528
Cdd:TIGR04523  523 KeKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEknkeieelkqtqkslKKKQEEKQELIdqkekekkDLI 602

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462523724 1529 RQVALKSEEATATHQQLEEAQKEhthllqsNQQLREILDELQARKLKLESQV 1580
Cdd:TIGR04523  603 KEIEEKEKKISSLEKELEKAKKE-------NEKLSSIIKNIKSKKNKLKQEV 647

PRK12704

phosphodiesterase; Provisional

1255-1444

3.45e-07

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 55.17 E-value: 3.45e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1255 AEQEASLQKLREELESQQKAERASLEQKnrQMLEQLKEEIEAsEKSEQAALNAAKEKALQQLREQLEgERKEAvatLEKE 1334
Cdd:PRK12704    36 AEEEAKRILEEAKKEAEAIKKEALLEAK--EEIHKLRNEFEK-ELRERRNELQKLEKRLLQKEENLD-RKLEL---LEKR 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1335 hSAELERLCSSLEAKHREvvssLQKKIQEAQQKEEAQLQKCLgqvehrvhqksyHVAGYEHElssllrEKRQEVegeher 1414
Cdd:PRK12704   109 -EEELEKKEKELEQKQQE----LEKKEEELEELIEEQLQELE------------RISGLTAE------EAKEIL------ 159

                          170       180       190
                   ....*....|....*....|....*....|
gi 2462523724 1415 rLDKMKEEHQQVMAKAREQYEaEERKQRAE 1444
Cdd:PRK12704   160 -LEKVEEEARHEAAVLIKEIE-EEAKEEAD 187

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1172-1380

4.25e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.38 E-value: 4.25e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1172 QRHLLESKQEKMQQLREKLcqEEEEEILRLHQQKEQSLSSLRERLQKAIEeEEARMREEESQRLSWLRAQVQsSTQADED 1251
Cdd:COG4942     18 QADAAAEAEAELEQLQQEI--AELEKELAALKKEEKALLKQLAALERRIA-ALARRIRALEQELAALEAELA-ELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1252 QIRAEQEASLQKLREELESQQKAERASLEQ------------KNRQMLEQLKEEIEaseksEQAALNAAKEKALQQLREQ 1319
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldavRRLQYLKYLAPARR-----EQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462523724 1320 LEGERKEaVATLEKEHSAELERLcSSLEAKHREVVSSLQKKIQEAQ------QKEEAQLQKCLGQVE 1380
Cdd:COG4942    169 LEAERAE-LEALLAELEEERAAL-EALKAERQKLLARLEKELAELAaelaelQQEAEELEALIARLE 233

mukB

chromosome partition protein MukB;

1170-1581

4.31e-07

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 55.35 E-value: 4.31e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1170 QDQRHLLESKQEKMQQLREKLcqeeeEEILRLHQQKEQSLSSLRERLQKaieeeearmreeesqrlswlraqVQSSTQAD 1249
Cdd:PRK04863   296 YTSRRQLAAEQYRLVEMAREL-----AELNEAESDLEQDYQAASDHLNL-----------------------VQTALRQQ 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1250 EDQIRAEqeASLQKLREELESQQKAERASLEQK--NRQMLEQLKEEIEaSEKSE----QAALNAAKEKALQQlreqlege 1323
Cdd:PRK04863   348 EKIERYQ--ADLEELEERLEEQNEVVEEADEQQeeNEARAEAAEEEVD-ELKSQladyQQALDVQQTRAIQY-------- 416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1324 rKEAVATLEKehsaeLERLC--SSLEAKhrevvsSLQKKIQEAQQKEEAQLQKCLgQVEHRVHQKSYHVAGYEHELSSLL 1401
Cdd:PRK04863   417 -QQAVQALER-----AKQLCglPDLTAD------NAEDWLEEFQAKEQEATEELL-SLEQKLSVAQAAHSQFEQAYQLVR 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1402 RekrqeVEGEHERrldkmKEEHQQVMAKAREqyeAEERKQRAELLGHLTGELERLQRahereletvRQEQHKRLEDLRR- 1480
Cdd:PRK04863   484 K-----IAGEVSR-----SEAWDVARELLRR---LREQRHLAEQLQQLRMRLSELEQ---------RLRQQQRAERLLAe 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1481 ------RHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQL-LDVQR-----------QVAL-----KSEE 1537
Cdd:PRK04863   542 fckrlgKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLqARIQRlaarapawlaaQDALarlreQSGE 621

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 2462523724 1538 ATATHQQLEEAQKEHTHLLQSNQQLReilDELQARKLKLESQVD 1581
Cdd:PRK04863   622 EFEDSQDVTEYMQQLLERERELTVER---DELAARKQALDEEIE 662

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

1239-1599

4.39e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 55.34 E-value: 4.39e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1239 RAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERAsLE---QKNRQMLEQLKEEIEASEKSE--QAALNAAKEKAL 1313
Cdd:COG3096    286 RALELRRELFGARRQLAEEQYRLVEMARELEELSARESD-LEqdyQAASDHLNLVQTALRQQEKIEryQEDLEELTERLE 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1314 QQ--LREQLEGERKEAVATLEkEHSAELERLCSSLeAKHREVVSSLQKKIQEAQQKEEAqlqkcLGQVEHRVHQKSYHVA 1391
Cdd:COG3096    365 EQeeVVEEAAEQLAEAEARLE-AAEEEVDSLKSQL-ADYQQALDVQQTRAIQYQQAVQA-----LEKARALCGLPDLTPE 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1392 GYEHELSSLlREKRQEVegeHERRLDKmkEEHQQVMAKAREQYEaeerkQRAELLGHLTGELERLQrAHE--RE-LETVR 1468
Cdd:COG3096    438 NAEDYLAAF-RAKEQQA---TEEVLEL--EQKLSVADAARRQFE-----KAYELVCKIAGEVERSQ-AWQtaRElLRRYR 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1469 QEQH--KRLEDLRRRHREQERKL---QDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQ 1543
Cdd:COG3096    506 SQQAlaQRLQQLRAQLAELEQRLrqqQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQ 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1544 QLEE-----------------AQKEHTHL-------LQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEA 1599
Cdd:COG3096    586 QLEQlrarikelaarapawlaAQDALERLreqsgeaLADSQEVTAAMQQLLEREREATVERDELAARKQALESQIERLSQ 665

CHASE3

COG5278

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

1150-1565

5.03e-07

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 54.91 E-value: 5.03e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1150 EQLSEAALKAMEEAVAQVLEQD-----QRHLLESKQEKMQQLREKLCQ-EEEEEILRLHQQKEQSLSSLRERLQKAIEEE 1223
Cdd:COG5278    113 EALIDQWLAELEQVIALRRAGGleaalALVRSGEGKALMDEIRARLLLlALALAALLLAAAALLLLLLALAALLALAELL 192

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1224 EARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQA 1303
Cdd:COG5278    193 LLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALALLLAALLLALLAALALAALLAAALLALAA 272

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1304 ALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgQVEHRV 1383
Cdd:COG5278    273 LLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAAALAALLALALATALAAAAA----ALALLA 348

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1384 HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERE 1463
Cdd:COG5278    349 ALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAAAAEAAAAAAAAAAASAAEALELAEAL 428

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1464 LETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQ 1543
Cdd:COG5278    429 AEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAAALAEAEAAAALAAAAALSLALALAAL 508

                          410       420
                   ....*....|....*....|..
gi 2462523724 1544 QLEEAQKEHTHLLQSNQQLREI 1565
Cdd:COG5278    509 LLAAAEAALAAALAAALASAEL 530

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1203-1760

5.10e-07

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 55.18 E-value: 5.10e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1203 QQKEQSLSSLRERLQKAieeeearmrEEESQRLSWLRAQVQSSTQADEDQIRAEQeaslqklreELESQQKAERASLEQK 1282
Cdd:pfam01576    8 QAKEEELQKVKERQQKA---------ESELKELEKKHQQLCEEKNALQEQLQAET---------ELCAEAEEMRARLAAR 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1283 nRQMLEQLKEEIEA--SEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHsaeLERLcsSLEAKhrevvsslQKK 1360
Cdd:pfam01576   70 -KQELEEILHELESrlEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQ---LEKV--TTEAK--------IKK 135

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1361 IQEAQQKEEAQ---LQKCLGQVEHRVHQKSYHVAGYEHELSSL--LREKRQEVEGEHERRLDKmKEEHQQVMAKAREQYE 1435
Cdd:pfam01576  136 LEEDILLLEDQnskLSKERKLLEERISEFTSNLAEEEEKAKSLskLKNKHEAMISDLEERLKK-EEKGRQELEKAKRKLE 214

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1436 AEE----------RKQRAELLGHLTGELERLQRAHER-ELETVRQEQhkrledLRRRHREQERKLQDLELDLET----RA 1500
Cdd:pfam01576  215 GEStdlqeqiaelQAQIAELRAQLAKKEEELQAALARlEEETAQKNN------ALKKIRELEAQISELQEDLESeraaRN 288

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1501 KDVKARLALLE-----------------VQEETARREKQQLLDVQRQValkSEEATATHQQLEEAQKEHThllQSNQQLR 1563
Cdd:pfam01576  289 KAEKQRRDLGEelealkteledtldttaAQQELRSKREQEVTELKKAL---EEETRSHEAQLQEMRQKHT---QALEELT 362

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1564 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLR--EVTVEENNASpHFEPDLHIEDLRKSLGTNQTK 1641
Cdd:pfam01576  363 EQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKklEGQLQELQAR-LSESERQRAELAEKLSKLQSE 441

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1642 --EVSSSLSQSKEDLY-----LDSLSSHnvwhllsaegvaLRSAKEFLVQQTR-----SMRRRQTALKAA--QQHWRHEL 1707
Cdd:pfam01576  442 leSVSSLLNEAEGKNIklskdVSSLESQ------------LQDTQELLQEETRqklnlSTRLRQLEDERNslQEQLEEEE 509

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462523724 1708 ASAQEVAKDPPGIKA-LEDMRKNLEKETRHLDEMKSAMRKghnlLKKKEEKLNQ 1760
Cdd:pfam01576  510 EAKRNVERQLSTLQAqLSDMKKKLEEDAGTLEALEEGKKR----LQRELEALTQ 559

DUF4659

pfam15558

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...

1286-1610

6.98e-07

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.

Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 53.89 E-value: 6.98e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1286 MLEQLKEEIEASEKSEQAALNAAKEK-ALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEA 1364
Cdd:pfam15558   13 MLARHKEEQRMRELQQQAALAWEELRrRDQKRQETLERERRLLLQQSQEQWQAEKEQRKARLGREERRRADRREKQVIEK 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1365 QQKEEAQLQKclgqVEHRVHQKsyhvagyehelsslLREKRQEVEG---EHERRLdKMKEEHQQVMaKAREQYEAEERKQ 1441
Cdd:pfam15558   93 ESRWREQAED----QENQRQEK--------------LERARQEAEQrkqCQEQRL-KEKEEELQAL-REQNSLQLQERLE 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1442 RAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLqDLELDLeTRAKDVKARLALLEVQE--ETARR 1519
Cdd:pfam15558  153 EACHKRQLKEREEQKKVQENNLSELLNHQARKVLVDCQAKAEELLRRL-SLEQSL-QRSQENYEQLVEERHRElrEKAQK 230

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1520 EKQQLLDVQRQVALKSEEatathqqleeaQKEHthllqsnqqlREILDELQARKLKLESQVdlLQAQSQQLQKHFSSLEA 1599
Cdd:pfam15558  231 EEEQFQRAKWRAEEKEEE-----------RQEH----------KEALAELADRKIQQARQV--AHKTVQDKAQRARELNL 287

                          330
                   ....*....|.
gi 2462523724 1600 EAQKKQHLLRE 1610
Cdd:pfam15558  288 EREKNHHILKL 298

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

1157-1527

7.83e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 54.46 E-value: 7.83e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1157 LKAMEEAVAQ------VLEQDQRHLLESKQEKMQQLREKLCQ-----EEEEEILRLHQQKEQSLSSLRERLQKAIEEEEA 1225
Cdd:pfam12128  310 LSAADAAVAKdrseleALEDQHGAFLDADIETAAADQEQLPSwqselENLEERLKALTGKHQDVTAKYNRRRSKIKEQNN 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1226 RMREEESQRLSWLR-------AQVQSSTQADEDQIRAEQEASLQKLREE-LESQQKAERASLEQKNRQMLEQLKEEIEAS 1297
Cdd:pfam12128  390 RDIAGIKDKLAKIReardrqlAVAEDDLQALESELREQLEAGKLEFNEEeYRLKSRLGELKLRLNQATATPELLLQLENF 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1298 E------KSEQAALNAAKEkALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHreVVSSLQKKIQEAQQKEEAQ 1371
Cdd:pfam12128  470 DerieraREEQEAANAEVE-RLQSELRQARKRRDQASEALRQASRRLEERQSALDELEL--QLFPQAGTLLHFLRKEAPD 546

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1372 LQKCLGQVE-----HRVHQKSYHVAGYEHELSSL----LREKRQEV------EGEHERRLDKMKEEHQQVMAKAREQYEA 1436
Cdd:pfam12128  547 WEQSIGKVIspellHRTDLDPEVWDGSVGGELNLygvkLDLKRIDVpewaasEEELRERLDKAEEALQSAREKQAAAEEQ 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1437 eerkqraelLGHLTGELERLQRAHERELETV--------------RQEQHKRLEDLRRRHREQERKLQDLELDLETRAKD 1502
Cdd:pfam12128  627 ---------LVQANGELEKASREETFARTALknarldlrrlfdekQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKK 697

                          410       420
                   ....*....|....*....|....*
gi 2462523724 1503 VKARLALLEVQEETARREKQQLLDV 1527
Cdd:pfam12128  698 HQAWLEEQKEQKREARTEKQAYWQV 722

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1172-1612

1.03e-06

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 54.03 E-value: 1.03e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1172 QRHLLESKQEKMQQLREKLCQEEEE--EILRLHQQKEQSLSSLRERLQKAIE--------------------------EE 1223
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESElkELEKKHQQLCEEKNALQEQLQAETElcaeaeemrarlaarkqeleeilhelES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1224 EARMREEESQRLSWLRAQVQSSTQADEDQIrAEQEASLQKLREE---LESQQKAERASL----EQKNRQMLEQLKEEIEA 1296
Cdd:pfam01576   83 RLEEEEERSQQLQNEKKKMQQHIQDLEEQL-DEEEAARQKLQLEkvtTEAKIKKLEEDIllleDQNSKLSKERKLLEERI 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1297 SEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSA--ELERLCSSLEAKH---REVVSSLQKKIQEAQ---QKE 1368
Cdd:pfam01576  162 SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGrqELEKAKRKLEGEStdlQEQIAELQAQIAELRaqlAKK 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1369 EAQLQKCLGQVEHRVHQKSyHVAGYEHELSSLLREKRQEVEGEHERR-------------LDKMKEEHQQVMAKAREQYE 1435
Cdd:pfam01576  242 EEELQAALARLEEETAQKN-NALKKIRELEAQISELQEDLESERAARnkaekqrrdlgeeLEALKTELEDTLDTTAAQQE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1436 AeeRKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLEldletrakdvKARLALlevqeE 1515
Cdd:pfam01576  321 L--RSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLE----------KAKQAL-----E 383

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1516 TARREKQQLLDVQRQVALKSEEA-TATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHF 1594
Cdd:pfam01576  384 SENAELQAELRTLQQAKQDSEHKrKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDV 463

                          490
                   ....*....|....*...
gi 2462523724 1595 SSLEAEAQKKQHLLREVT 1612
Cdd:pfam01576  464 SSLESQLQDTQELLQEET 481

mukB

chromosome partition protein MukB;

1255-1505

1.20e-06

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 54.19 E-value: 1.20e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1255 AEQEASLQKLREELeSQQKAERASLEQKNRQM---LEQLKEEIEASEKSE-QAAL--NAAKEKALQQLREQLEgERKEAV 1328
Cdd:PRK04863   833 ADPEAELRQLNRRR-VELERALADHESQEQQQrsqLEQAKEGLSALNRLLpRLNLlaDETLADRVEEIREQLD-EAEEAK 910

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1329 ATLEK--EHSAELERLCSSLEAKHREVvSSLQKKIQEAQQKEEAQLQKC--LGQVEHRVHQKSYHVA----GYEHELSSL 1400
Cdd:PRK04863   911 RFVQQhgNALAQLEPIVSVLQSDPEQF-EQLKQDYQQAQQTQRDAKQQAfaLTEVVQRRAHFSYEDAaemlAKNSDLNEK 989

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1401 LREKRQEVEGEherrLDKMKEEHQQ----------VMAKAREQYEA-----EERKQRAELLG-HLTGELERLQRAHEREL 1464
Cdd:PRK04863   990 LRQRLEQAEQE----RTRAREQLRQaqaqlaqynqVLASLKSSYDAkrqmlQELKQELQDLGvPADSGAEERARARRDEL 1065

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 2462523724 1465 etvrqeqHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA 1505
Cdd:PRK04863  1066 -------HARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRK 1099

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

1313-1690

1.22e-06

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 53.57 E-value: 1.22e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1313 LQQLREQLEGERKEAVATLEKEHSAELERLCS--------------SLEAKHREVVSSLQ--KKIQEAQQKEEAQLQ--- 1373
Cdd:pfam05483   50 LEQVANSGDCHYQEGLKDSDFENSEGLSRLYSklykeaekikkwkvSIEAELKQKENKLQenRKIIEAQRKAIQELQfen 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1374 -KCLGQVEHRVHQKSYHVA--GYEHELSSLLRE---------KRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQ 1441
Cdd:pfam05483  130 eKVSLKLEEEIQENKDLIKenNATRHLCNLLKEtcarsaektKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENA 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1442 RAELLGHLTGELERLQRAhERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARR-- 1519
Cdd:pfam05483  210 RLEMHFKLKEDHEKIQHL-EEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKEli 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1520 EKQQLL---------DVQRQVALKS--EE----ATATHQQL---EEAQKEHTHLLQSNQQLreILDELQARKLKLESQVD 1581
Cdd:pfam05483  289 EKKDHLtkeledikmSLQRSMSTQKalEEdlqiATKTICQLteeKEAQMEELNKAKAAHSF--VVTEFEATTCSLEELLR 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1582 LLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNAsphfepDLHIEDLRKSLGTNQT--------KEVSSSLSQSKED 1653
Cdd:pfam05483  367 TEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNK------EVELEELKKILAEDEKlldekkqfEKIAEELKGKEQE 440

                          410       420       430
                   ....*....|....*....|....*....|....*..
gi 2462523724 1654 LYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMR 1690
Cdd:pfam05483  441 LIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLK 477

PRK00106

ribonuclease Y;

1240-1438

1.35e-06

ribonuclease Y;

Pssm-ID: 178867 [Multi-domain] Cd Length: 535 Bit Score: 53.33 E-value: 1.35e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1240 AQVQSSTQADEDQIRAEQEAslQKLREELESQQKAERasleQKNRQMLEQLKEEIEASEKSEQAALNaaKEKALQQLREQ 1319
Cdd:PRK00106    62 AKRESKALKKELLLEAKEEA--RKYREEIEQEFKSER----QELKQIESRLTERATSLDRKDENLSS--KEKTLESKEQS 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1320 LE------GERKEAVATLEKEHSAELERLCSSLEAKHREVVsslqkkiqeaqqkeeaqlqkcLGQVEHRVhqksyhvagy 1393
Cdd:PRK00106   134 LTdkskhiDEREEQVEKLEEQKKAELERVAALSQAEAREII---------------------LAETENKL---------- 182

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462523724 1394 EHELSSLLREKRQEVegehERRLDKM-KEEHQQVMAKAREQYEAEE 1438
Cdd:PRK00106   183 THEIATRIREAEREV----KDRSDKMaKDLLAQAMQRLAGEYVTEQ 224

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1415-1635

1.51e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 1.51e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1415 RLDKMKEEHQQVMAkAREqyEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLEL 1494
Cdd:COG4913    226 AADALVEHFDDLER-AHE--ALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRA 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1495 D---LETRAKDVKARLALLEVQEETARREKQQlLDVQRQVALKSEEATAThQQLEEAQKEHTHLlqsNQQLREI------ 1565
Cdd:COG4913    303 ElarLEAELERLEARLDALREELDELEAQIRG-NGGDRLEQLEREIERLE-RELEERERRRARL---EALLAALglplpa 377

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462523724 1566 -LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVE----ENNASPHfepDLHIEDLRKSL 1635
Cdd:COG4913    378 sAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEiaslERRKSNI---PARLLALRDAL 449

PRK12704

phosphodiesterase; Provisional

1390-1568

1.62e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.86 E-value: 1.62e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1390 VAGYEHELSSLLREKRQEVEGEHERRLDKMKEEhqqvMAKAREQYEAEERKQRAELlghltGELERLQRAHERELEtvrq 1469
Cdd:PRK12704    33 IKEAEEEAKRILEEAKKEAEAIKKEALLEAKEE----IHKLRNEFEKELRERRNEL-----QKLEKRLLQKEENLD---- 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1470 eqhKRLEDLRRRhreqERKLQDLELDLETRAKDVKARlallevQEETARREKQQLLDVQRQVALKSEEATAthQQLEEAQ 1549
Cdd:PRK12704   100 ---RKLELLEKR----EEELEKKEKELEQKQQELEKK------EEELEELIEEQLQELERISGLTAEEAKE--ILLEKVE 164

                          170
                   ....*....|....*....
gi 2462523724 1550 KEHTHllQSNQQLREILDE 1568
Cdd:PRK12704   165 EEARH--EAAVLIKEIEEE 181

PRK12704

phosphodiesterase; Provisional

1413-1578

1.67e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.86 E-value: 1.67e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1413 ERRLDKMKEEHQQVMAKAREqyEAEERKQRAELlghltgelerlqrahereleTVRQEQHKRLEDLRRRHREQERKLQDL 1492
Cdd:PRK12704    30 EAKIKEAEEEAKRILEEAKK--EAEAIKKEALL--------------------EAKEEIHKLRNEFEKELRERRNELQKL 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1493 EldletraKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHthllqsNQQLREI--LDELQ 1570
Cdd:PRK12704    88 E-------KRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQ------LQELERIsgLTAEE 154


                   ....*...
gi 2462523724 1571 ARKLKLES 1578
Cdd:PRK12704   155 AKEILLEK 162

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1401-1604

1.91e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.46 E-value: 1.91e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1401 LREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEER-KQRAELLGHLTGELERLQR---AHERELETVRQEQHKRLE 1476
Cdd:COG4942     25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiAALARRIRALEQELAALEAelaELEKEIAELRAELEAQKE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1477 DLRRRHREQERKLQDLELDLETRAKDVKA---RLALL----EVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQ 1549
Cdd:COG4942    105 ELAELLRALYRLGRQPPLALLLSPEDFLDavrRLQYLkylaPARREQAEELRADLAELAALRAELEAERAELEALLAELE 184

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462523724 1550 KEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKK 1604
Cdd:COG4942    185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1154-1572

2.46e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.00 E-value: 2.46e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1154 EAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEeeeilRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQ 1233
Cdd:COG4913    311 LERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLE-----RELEERERRRARLEALLAALGLPLPASAEEFAAL 385

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1234 RLSW--LRAQVQSSTQADEDQiRAEQEASLQKLREELEsQQKAERASLEQKN-------RQMLEQLKEEIEASE------ 1298
Cdd:COG4913    386 RAEAaaLLEALEEELEALEEA-LAEAEAALRDLRRELR-ELEAEIASLERRKsniparlLALRDALAEALGLDEaelpfv 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1299 ------KSEQAALNAAKEKAL-----------------------QQLREQLEGERKEAVATLEKEHSAELERLCSSLEAK 1349
Cdd:COG4913    464 gelievRPEEERWRGAIERVLggfaltllvppehyaaalrwvnrLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFK 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1350 ----HREVVSSLQKKIQEAQQKEEAQLQKC------LGQV--EHRVHQK-------SYHVAGYE-----HELSSLLREKR 1405
Cdd:COG4913    544 phpfRAWLEAELGRRFDYVCVDSPEELRRHpraitrAGQVkgNGTRHEKddrrrirSRYVLGFDnraklAALEAELAELE 623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1406 QEVEgEHERRLDKMKEEHQQvMAKAREQYEAEERKQRAEL--------LGHLTGELERLQRAHE--RELETVRQEQHKRL 1475
Cdd:COG4913    624 EELA-EAEERLEALEAELDA-LQERREALQRLAEYSWDEIdvasaereIAELEAELERLDASSDdlAALEEQLEELEAEL 701

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1476 EDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQ-KEHTH 1554
Cdd:COG4913    702 EELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIdALRAR 781

                          490
                   ....*....|....*...
gi 2462523724 1555 LLQSNQQLREILDELQAR 1572
Cdd:COG4913    782 LNRAEEELERAMRAFNRE 799

FAM184

pfam15665

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

1256-1489

2.69e-06

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

Pssm-ID: 464788 [Multi-domain] Cd Length: 211 Bit Score: 50.43 E-value: 2.69e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1256 EQEASLQKLREelesQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAAlnaakeKALQQLREQLEGERKEAVATLEK-E 1334
Cdd:pfam15665   11 EHEAEIQALKE----AHEEEIQQILAETREKILQYKSKIGEELDLKRRI------QTLEESLEQHERMKRQALTEFEQyK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1335 HSAELERLCssLEAKHREVVSSLQKKIQEAQQKEEAQLQKclgqvehrvhqksyhvagyehelsslLREKRQEVEGEHER 1414
Cdd:pfam15665   81 RRVEERELK--AEAEHRQRVVELSREVEEAKRAFEEKLES--------------------------FEQLQAQFEQEKRK 132

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462523724 1415 RLDKMKEEHQQVMAKAREQYEAEERKqraellghLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKL 1489
Cdd:pfam15665  133 ALEELRAKHRQEIQELLTTQRAQSAS--------SLAEQEKLEELHKAELESLRKEVEDLRKEKKKLAEEYEQKL 199

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1438-1718

2.72e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.61 E-value: 2.72e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1438 ERKQRAELLGHLTGELERLQRAHErELETVRqEQHKRLEDLRRRHREQERKLQDLEL--DLETRAKDVKA--RLALLEVQ 1513
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHE-ALEDAR-EQIELLEPIRELAERYAAARERLAEleYLRAALRLWFAqrRLELLEAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1514 EETARREKQQLldvQRQVALKSEEATATHQQLEEAQKEHthLLQSNQQLREILDELQARKLKLESQvdllqaqsqqlqkh 1593
Cdd:COG4913    297 LEELRAELARL---EAELERLEARLDALREELDELEAQI--RGNGGDRLEQLEREIERLERELEER-------------- 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1594 fsslEAEAQKKQHLLREVtveennaspHFEPDLHIEDLRKSLgtNQTKEVSSSLSQSKEDLyldslssHNVWHLLSAEGV 1673
Cdd:COG4913    358 ----ERRRARLEALLAAL---------GLPLPASAEEFAALR--AEAAALLEALEEELEAL-------EEALAEAEAALR 415

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 2462523724 1674 ALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPP 1718
Cdd:COG4913    416 DLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAEL 460

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

1240-1371

2.79e-06

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 51.77 E-value: 2.79e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1240 AQVQSSTQADEDQIRAEQEAslQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQ 1319
Cdd:TIGR02794   50 QQANRIQQQKKPAAKKEQER--QKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAK 127

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462523724 1320 LEGERK-------EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ 1371
Cdd:TIGR02794  128 QAAEAKakaeaeaERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAE 186

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

1332-1610

3.15e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 52.43 E-value: 3.15e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1332 EKEHSAELERLCSSLEAKHREVvsSLQKKIQEAQQKEEAQLQKclgqvehrvhQKSYHVagyEHELSSLlrekrqevegE 1411
Cdd:pfam17380  291 EKFEKMEQERLRQEKEEKAREV--ERRRKLEEAEKARQAEMDR----------QAAIYA---EQERMAM----------E 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1412 HERRLDKMK-EEHQQVMAKAREQYEAEERKQraellghlTGELERLQRAHERELETVRQE-----QHKRLEDlrrrhrEQ 1485
Cdd:pfam17380  346 RERELERIRqEERKRELERIRQEEIAMEISR--------MRELERLQMERQQKNERVRQEleaarKVKILEE------ER 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1486 ERKLQDLELDLET-RAKDVKARLALLEVQEETARREKQQLldvqRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLRE 1564
Cdd:pfam17380  412 QRKIQQQKVEMEQiRAEQEEARQREVRRLEEERAREMERV----RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRK 487

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 2462523724 1565 ILDELqaRKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLRE 1610
Cdd:pfam17380  488 RAEEQ--RRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYE 531

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1253-1618

3.45e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.08 E-value: 3.45e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1253 IRAEQEASLQKLREELESQQkaerASLEQKNRQMLEQLKEEIEASEksEQAALNAAKEKALQQLREQLEGERKEavatlE 1332
Cdd:COG4717     43 IRAMLLERLEKEADELFKPQ----GRKPELNLKELKELEEELKEAE--EKEEEYAELQEELEELEEELEELEAE-----L 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1333 KEHSAELERLcssleakhrEVVSSLQKKIQEAQQKEE--AQLQKCLGQVEHRVHQksyhVAGYEHELSSlLREKRQEVEG 1410
Cdd:COG4717    112 EELREELEKL---------EKLLQLLPLYQELEALEAelAELPERLEELEERLEE----LRELEEELEE-LEAELAELQE 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1411 EHERRLDKMKEEHQQVMAKAREQYEA--EERKQRAELLGHLTGELERLQRAHER-ELETVRQEQHKRLEDLRR------- 1480
Cdd:COG4717    178 ELEELLEQLSLATEEELQDLAEELEElqQRLAELEEELEEAQEELEELEEELEQlENELEAAALEERLKEARLllliaaa 257

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1481 -----------------------------------------RHREQERKLQDLELDLETRAKDVKARLALLEVQEETARR 1519
Cdd:COG4717    258 llallglggsllsliltiagvlflvlgllallflllarekaSLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPE 337

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1520 EKQQLLDVQRQVALKSEEATATHQQL--EEAQKEHTHLLQSNQ-----QLREILD------ELQARKLKLESQVDLLQAQ 1586
Cdd:COG4717    338 ELLELLDRIEELQELLREAEELEEELqlEELEQEIAALLAEAGvedeeELRAALEqaeeyqELKEELEELEEQLEELLGE 417

                          410       420       430
                   ....*....|....*....|....*....|....
gi 2462523724 1587 SQQLQKHFS--SLEAEAQKKQHLLREVTVEENNA 1618
Cdd:COG4717    418 LEELLEALDeeELEEELEELEEELEELEEELEEL 451

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

1267-1564

3.64e-06

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 52.03 E-value: 3.64e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1267 ELESQQKAERASLEQKNRQMlEQLKEEIEASEKSEQAALNAAKE---------KALQQLREQLEGERKEA---------- 1327
Cdd:pfam05483  272 QLEEKTKLQDENLKELIEKK-DHLTKELEDIKMSLQRSMSTQKAleedlqiatKTICQLTEEKEAQMEELnkakaahsfv 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1328 -------VATLEKEHSAELERLCSSlEAKHREVVSSLQKKIQEAQQK---------EEAQLQKCLGQVEHRVHQK----- 1386
Cdd:pfam05483  351 vtefeatTCSLEELLRTEQQRLEKN-EDQLKIITMELQKKSSELEEMtkfknnkevELEELKKILAEDEKLLDEKkqfek 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1387 -SYHVAGYEHELSSLLREKRQEVEG-EHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGH---LTGELERL-QRAH 1460
Cdd:pfam05483  430 iAEELKGKEQELIFLLQAREKEIHDlEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHcdkLLLENKELtQEAS 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1461 ERELETVRQEQH------------KRLEDLRRRHREQERKLQDLELDLETRAKDVKARLallEVQEETARREKQQLLDVQ 1528
Cdd:pfam05483  510 DMTLELKKHQEDiinckkqeermlKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKL---DKSEENARSIEYEVLKKE 586

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 2462523724 1529 RQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLRE 1564
Cdd:pfam05483  587 KQMKILENKCNNLKKQIENKNKNIEELHQENKALKK 622

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

1402-1574

4.01e-06

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 51.07 E-value: 4.01e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1402 REKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRR 1481
Cdd:pfam13868   31 KKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVERI 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1482 HREQERKLQD-LELDLETR---AKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHT---- 1553
Cdd:pfam13868  111 QEEDQAEAEEkLEKQRQLReeiDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEEREAEREEIEEEKEREIarlr 190

                          170       180
                   ....*....|....*....|.
gi 2462523724 1554 HLLQSNQQLREILDELQARKL 1574
Cdd:pfam13868  191 AQQEKAQDEKAERDELRAKLY 211

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

1233-1572

4.19e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 51.82 E-value: 4.19e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1233 QRLSWLRAQVQSSTQADEDQIRAEQEA-SLQKLREELESQ---QKAERASLEQKNRQMLEQLKEEIEASE--KSEQAALN 1306
Cdd:pfam07888   42 ERAELLQAQEAANRQREKEKERYKRDReQWERQRRELESRvaeLKEELRQSREKHEELEEKYKELSASSEelSEEKDALL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1307 AAKEKALQQLREQLEGERKEAVATLEKEhsAELERLcssleaKHREVVSSLQKKIQEAQQKeeaQLQKCLGQVEHRVHQK 1386
Cdd:pfam07888  122 AQRAAHEARIRELEEDIKTLTQRVLERE--TELERM------KERAKKAGAQRKEEEAERK---QLQAKLQQTEEELRSL 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1387 SYHVAGYEHEL----SSLLR-----EKRQEVEGEHERRLDKMKEEHQQvMAKAREQYEAEERKqrAELLGHLTGELERLQ 1457
Cdd:pfam07888  191 SKEFQELRNSLaqrdTQVLQlqdtiTTLTQKLTTAHRKEAENEALLEE-LRSLQERLNASERK--VEGLGEELSSMAAQR 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1458 RAHERELETVRQEQHK---RLEDLRRRHRE------QERK--LQDLELDLETRAKDVKARLALLE-VQEETARREKQQL- 1524
Cdd:pfam07888  268 DRTQAELHQARLQAAQltlQLADASLALREgrarwaQEREtlQQSAEADKDRIEKLSAELQRLEErLQEERMEREKLEVe 347

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462523724 1525 ----LDVQR-QVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQAR 1572
Cdd:pfam07888  348 lgreKDCNRvQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQR 400

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

1252-1368

5.12e-06

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 51.75 E-value: 5.12e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1252 QIRAEQEA-SLQKLREELESQQKaeraSLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVAT 1330
Cdd:PRK00409   529 ERELEQKAeEAEALLKEAEKLKE----ELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYASV 604

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 2462523724 1331 LEKEHSAELERLCSSLEAKHREvvsslqKKIQEAQQKE 1368
Cdd:PRK00409   605 KAHELIEARKRLNKANEKKEKK------KKKQKEKQEE 636

EzrA

pfam06160

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...

1241-1573

6.52e-06

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.

Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 51.01 E-value: 6.52e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1241 QVQSSTQADEDQIRAEQEASLQKLREELESqqkaeraslEQKNRQMLEQLKEEIEASEKsEQAALNAAKEKALQQLREQL 1320
Cdd:pfam06160   86 KALDEIEELLDDIEEDIKQILEELDELLES---------EEKNREEVEELKDKYRELRK-TLLANRFSYGPAIDELEKQL 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1321 EgerkeavaTLEKEHSaELERLCSS---LEAkhREVVSSLQKKIQEAQQKEE------AQLQKCL-GQVEhrvhqksyhv 1390
Cdd:pfam06160  156 A--------EIEEEFS-QFEELTESgdyLEA--REVLEKLEEETDALEELMEdipplyEELKTELpDQLE---------- 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1391 agyehELSSLLRE-KRQEVEGEH---ERRLDKMKEEHQQVMA--KAREQYEAEerkqraELLGHLTGELERLQRAHEREL 1464
Cdd:pfam06160  215 -----ELKEGYREmEEEGYALEHlnvDKEIQQLEEQLEENLAllENLELDEAE------EALEEIEERIDQLYDLLEKEV 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1465 ETvRQEQHKRLEDLRRRHREQERKLQDLELDLETrakdVKARLALLEVQEETARREKQQLLDVQRQVAL---KSEEATAT 1541
Cdd:pfam06160  284 DA-KKYVEKNLPEIEDYLEHAEEQNKELKEELER----VQQSYTLNENELERVRGLEKQLEELEKRYDEiveRLEEKEVA 358

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 2462523724 1542 H-----------QQLEEAQKEHTHLLQSNQQLREilDELQARK 1573
Cdd:pfam06160  359 YselqeeleeilEQLEEIEEEQEEFKESLQSLRK--DELEARE 399

cd00201

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ...

59-89

7.01e-06

Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 44.44 E-value: 7.01e-06

                           10        20        30
                   ....*....|....*....|....*....|.
gi 2462523724   59 PGEWKPCQDITGDIYYFNFANGQSMWDHPCD 89
Cdd:cd00201      1 PPGWEERWDPDGRVYYYNHNTKETQWEDPRE 31

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

1154-1415

7.55e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 51.28 E-value: 7.55e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1154 EAALKAMEEAVAQVLEQD-QRHLLESKQEKMQQLREKLCQEEEEEIL---RLHQQKEQSLSSLRERL-----QKAIEEEE 1224
Cdd:pfam17380  332 QAAIYAEQERMAMERERElERIRQEERKRELERIRQEEIAMEISRMReleRLQMERQQKNERVRQELeaarkVKILEEER 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1225 ARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR-EELESQQKAE--RASLEQKNRQMLEQLKEEIEASEKSE 1301
Cdd:pfam17380  412 QRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRlEEQERQQQVErlRQQEEERKRKKLELEKEKRDRKRAEE 491

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1302 QAALNAAKEKALQQlREQLEGERKEAVatLEKEhsaelerlcssLEAKHREVVSSLQKKIQEAQQKEEAQLQKclgqvEH 1381
Cdd:pfam17380  492 QRRKILEKELEERK-QAMIEEERKRKL--LEKE-----------MEERQKAIYEEERRREAEEERRKQQEMEE-----RR 552

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 2462523724 1382 RVHQKSYHVAGYEHELSSLLREK---RQEVEGEHERR 1415
Cdd:pfam17380  553 RIQEQMRKATEERSRLEAMERERemmRQIVESEKARA 589

tolA

PRK09510

cell envelope integrity inner membrane protein TolA; Provisional

1239-1374

8.32e-06

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 50.58 E-value: 8.32e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1239 RAQVQSSTQADEDQIR--AEQEASLQKLREELESQQKAERAslEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKAlqql 1316
Cdd:PRK09510    80 QRKKKEQQQAEELQQKqaAEQERLKQLEKERLAAQEQKKQA--EEAAKQAALKQKQAEEAAAKAAAAAKAKAEAEA---- 153

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462523724 1317 rEQLEGERKEAVATLEKEHSAELERLCSSlEAKHREVVSSLQKKIQEAQQKEEAQLQK 1374
Cdd:PRK09510   154 -KRAAAAAKKAAAEAKKKAEAEAAKKAAA-EAKKKAEAEAAAKAAAEAKKKAEAEAKK 209

CHASE3

COG5278

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

1254-1650

8.69e-06

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 50.68 E-value: 8.69e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1254 RAEQEASLQKLREEL--ESQQKAERASLEQKNRQMLEQLKEEIEAS-EKSEQAALNAAKEKALQQLREQLEGERKEAVAT 1330
Cdd:COG5278     85 RAEIDELLAELRSLTadNPEQQARLDELEALIDQWLAELEQVIALRrAGGLEAALALVRSGEGKALMDEIRARLLLLALA 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1331 LEKEHSAELERLcsSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEG 1410
Cdd:COG5278    165 LAALLLAAAALL--LLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALAL 242

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1411 EHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQ 1490
Cdd:COG5278    243 ALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAA 322

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1491 DLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQ 1570
Cdd:COG5278    323 AALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAA 402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1571 ARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQS 1650
Cdd:COG5278    403 AAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAA 482

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1327-1572

1.20e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 1.20e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1327 AVATLEKEHSAELERLcssleakhREVVSSLQKKIQEaQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSL---LRE 1403
Cdd:COG4942     17 AQADAAAEAEAELEQL--------QQEIAELEKELAA-LKKEEKALLKQLAALERRIAALARRIRALEQELAALeaeLAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1404 KRQEVEgEHERRLDKMKEEHQQVMAKAREQyeaeERKQRAELLGHLTGELERLQRAheRELETVRQEQHKRLEDLRRrhr 1483
Cdd:COG4942     88 LEKEIA-ELRAELEAQKEELAELLRALYRL----GRQPPLALLLSPEDFLDAVRRL--QYLKYLAPARREQAEELRA--- 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1484 eqerKLQDLElDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEeatathQQLEEAQKEHTHLLQSNQQLR 1563
Cdd:COG4942    158 ----DLAELA-ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLE------KELAELAAELAELQQEAEELE 226


                   ....*....
gi 2462523724 1564 EILDELQAR 1572
Cdd:COG4942    227 ALIARLEAE 235

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1438-1579

1.27e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 48.77 E-value: 1.27e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1438 ERKQRAELLGHLTGELERLqrahERELETVRqeqhKRLEDLRRRHREQERKLQDLELDLET---RAKDVKARLAL----- 1509
Cdd:COG1579     18 ELDRLEHRLKELPAELAEL----EDELAALE----ARLEAAKTELEDLEKEIKRLELEIEEveaRIKKYEEQLGNvrnnk 89

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462523724 1510 ----LEVQEETARREKQQL----LDVQRQVALKSEEATATHQQLEEAQKEHTHLLqsnQQLREILDELQARKLKLESQ 1579
Cdd:COG1579     90 eyeaLQKEIESLKRRISDLedeiLELMERIEELEEELAELEAELAELEAELEEKK---AELDEELAELEAELEELEAE 164

PLN03229

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional

1123-1411

1.37e-05

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional

Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 50.24 E-value: 1.37e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1123 DPEEKVAVSPTPPVSPEVRSTEPVAP--PEQLSEA----------ALKAMEEAVAQVLEQDQRHLLESK--QEKMQQLRE 1188
Cdd:PLN03229   414 DPERKVNMKKREAVKTPVRELEGEVEklKEQILKAkessskpselALNEMIEKLKKEIDLEYTEAVIAMglQERLENLRE 493

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1189 KLCQEEEE----------EILRLHQQKEQSLS------SLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDq 1252
Cdd:PLN03229   494 EFSKANSQdqlmhpvlmeKIEKLKDEFNKRLSrapnylSLKYKLDMLNEFSRAKALSEKKSKAEKLKAEINKKFKEVMD- 572

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1253 iRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASE----KSEQAALNAAKEKALQQLREQLEGERKEAV 1328
Cdd:PLN03229   573 -RPEIKEKMEALKAEVASSGASSGDELDDDLKEKVEKMKKEIELELagvlKSMGLEVIGVTKKNKDTAEQTPPPNLQEKI 651

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1329 ATLEKEHSAELERLCSSLEAKHRevVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGyehelSSLLREKRQEV 1408
Cdd:PLN03229   652 ESLNEEINKKIERVIRSSDLKSK--IELLKLEVAKASKTPDVTEKEKIEALEQQIKQKIAEALN-----SSELKEKFEEL 724


                   ...
gi 2462523724 1409 EGE 1411
Cdd:PLN03229   725 EAE 727

PRK10929

putative mechanosensitive channel protein; Provisional

1235-1603

1.43e-05

putative mechanosensitive channel protein; Provisional

Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 50.44 E-value: 1.43e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1235 LSWLRAQ-VQSSTQADEDQIRAE-QEASLQKlreeleSQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAakEKA 1312
Cdd:PRK10929     9 MAWLLSWgAYAATAPDEKQITQElEQAKAAK------TPAQAEIVEALQSALNWLEERKGSLERAKQYQQVIDNF--PKL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1313 LQQLREQLEGERKE--------AVATLEKE------HSAELERLCSSLEAKHREVVSSLQkkiQEAQQKEEAqlQKCLGQ 1378
Cdd:PRK10929    81 SAELRQQLNNERDEprsvppnmSTDALEQEilqvssQLLEKSRQAQQEQDRAREISDSLS---QLPQQQTEA--RRQLNE 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1379 VEHRVH-------------------QKSYHVAGY-EHELSSLLREKRQEVEgehERRLDKMKEEHQQVMAK--------- 1429
Cdd:PRK10929   156 IERRLQtlgtpntplaqaqltalqaESAALKALVdELELAQLSANNRQELA---RLRSELAKKRSQQLDAYlqalrnqln 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1430 AREQYEAEERKQRAELLGHLTGEL-----ERLQRahERELETVRQEQHKRLEDLRRRHReqerklqdleldlETRAKDVK 1504
Cdd:PRK10929   233 SQRQREAERALESTELLAEQSGDLpksivAQFKI--NRELSQALNQQAQRMDLIASQQR-------------QAASQTLQ 297

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1505 ARLALlevqeeTARREKQQLLDVQRQV--ALKSEEAtathqQLEEAQKEhthllqsnQQLREILDELQARKLKLESQVDL 1582
Cdd:PRK10929   298 VRQAL------NTLREQSQWLGVSNALgeALRAQVA-----RLPEMPKP--------QQLDTEMAQLRVQRLRYEDLLNK 358

                          410       420
                   ....*....|....*....|.
gi 2462523724 1583 LQAQSQQLQKHFSSLEAEAQK 1603
Cdd:PRK10929   359 QPQLRQIRQADGQPLTAEQNR 379

pfam00397

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ...

58-87

1.73e-05

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro.

Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 43.26 E-value: 1.73e-05

                           10        20        30
                   ....*....|....*....|....*....|
gi 2462523724   58 LPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:pfam00397    1 LPPGWEERWDPDGRVYYYNHETGETQWEKP 30

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

1235-1533

2.06e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 49.13 E-value: 2.06e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1235 LSWLRAQVQSSTQADEDQIRAEqeasLQKLREELESQQK---AERASLEQKNRQmLEQLKEEIEASEKSEQAALN--AAK 1309
Cdd:COG4372     25 LIAALSEQLRKALFELDKLQEE----LEQLREELEQAREeleQLEEELEQARSE-LEQLEEELEELNEQLQAAQAelAQA 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1310 EKALQQLREQLEGERKEaVATLEKEhSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEE--AQLQKCLGQVEHRVHQKS 1387
Cdd:COG4372    100 QEELESLQEEAEELQEE-LEELQKE-RQDLEQQRKQLEAQIAELQSEIAEREEELKELEEqlESLQEELAALEQELQALS 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1388 yhVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETV 1467
Cdd:COG4372    178 --EAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEV 255

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462523724 1468 RQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVAL 1533
Cdd:COG4372    256 ILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAAL 321

PTZ00121

MAEBL; Provisional

903-1374

2.06e-05

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.14 E-value: 2.06e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  903 KASEKEAPEDTVDAGEEGSRREEAAK--EPKKKASALEEGSSDASQELEISEHMKEPQlsdsiasdpksfhgldfgfrsr 980
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKkaEEAKKADEAKKKAEEAKKKADEAKKAAEAK---------------------- 1509

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  981 isehlldvdvlspvlggacRQAQQPLGIEDK---DDSQSSQDELQSKQSKGLEERyhRLSPPLPHEERAQSPPRSLATEE 1057
Cdd:PTZ00121  1510 -------------------KKADEAKKAEEAkkaDEAKKAEEAKKADEAKKAEEK--KKADELKKAEELKKAEEKKKAEE 1568

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1058 EPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEkvavsPTPPVS 1137
Cdd:PTZ00121  1569 AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQ-----LKKKEA 1643

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1138 PEVRSTEPVAPPEQlsEAALKAMEEAVAQvlEQDQRHLLESKQEKMQQlreklcqeeeeeilrlhQQKEQSLSSLRERLQ 1217
Cdd:PTZ00121  1644 EEKKKAEELKKAEE--ENKIKAAEEAKKA--EEDKKKAEEAKKAEEDE-----------------KKAAEALKKEAEEAK 1702

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1218 KAIEEEEARMREEesqrlswlRAQVQSSTQADEDQIRAEQEAslqklREELESQQKAERASLEQKNRQMLEQLKEEIEAS 1297
Cdd:PTZ00121  1703 KAEELKKKEAEEK--------KKAEELKKAEEENKIKAEEAK-----KEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1298 EKSEQAALNAAKEKALQQ--LREQLEGERK--------EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQK 1367
Cdd:PTZ00121  1770 AEEIRKEKEAVIEEELDEedEKRRMEVDKKikdifdnfANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAF 1849


                   ....*..
gi 2462523724 1368 EEAQLQK 1374
Cdd:PTZ00121  1850 EKHKFNK 1856

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

1437-1644

2.13e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 49.13 E-value: 2.13e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1437 EERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEET 1516
Cdd:COG4372      9 GKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQ 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1517 ARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSS 1596
Cdd:COG4372     89 LQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAA 168

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462523724 1597 LEAEAQ-----KKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVS 1644
Cdd:COG4372    169 LEQELQalseaEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELL 221

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

1126-1522

2.59e-05

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 49.37 E-value: 2.59e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1126 EKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLcqeeeeeilrlhQQK 1205
Cdd:pfam09731   99 SEVAEEEKEATKDAAEAKAQLPKSEQEKEKALEEVLKEAISKAESATAVAKEAKDDAIQAVKAHT------------DSL 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1206 EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIrAEQEASLQKLREELESQQKAERAslEQKNRQ 1285
Cdd:pfam09731  167 KEASDTAEISREKATDSALQKAEALAEKLKEVINLAKQSEEEAAPPLL-DAAPETPPKLPEHLDNVEEKVEK--AQSLAK 243

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1286 MLEQLKEEIEASEkseqaalnaakekalQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVvSSLQKKIQEAQ 1365
Cdd:pfam09731  244 LVDQYKELVASER---------------IVFQQELVSIFPDIIPVLKEDNLLSNDDLNSLIAHAHREI-DQLSKKLAELK 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1366 QKEEAQLQKCLGQVEHrvhqksyhvagyehELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEerkqrael 1445
Cdd:pfam09731  308 KREEKHIERALEKQKE--------------ELDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEK-------- 365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1446 lghLTGELERLQRAHERELETVRQEQHkrlEDLRRRHR-------EQERKLQDLELD-LETRAKDVKARLALLEVQEETA 1517
Cdd:pfam09731  366 ---LRTELERQAEAHEEHLKDVLVEQE---IELQREFLqdikekvEEERAGRLLKLNeLLANLKGLEKATSSHSEVEDEN 439


                   ....*
gi 2462523724 1518 RREKQ 1522
Cdd:pfam09731  440 RKAQQ 444

PRK11637

AmiB activator; Provisional

1155-1367

3.07e-05

AmiB activator; Provisional

Pssm-ID: 236942 [Multi-domain] Cd Length: 428 Bit Score: 48.54 E-value: 3.07e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1155 AALKAMEEAVAQVLEQdqrhlLESKQEKMQQLrEKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMRE----- 1229
Cdd:PRK11637    75 AQLKKQEEAISQASRK-----LRETQNTLNQL-NKQIDELNASIAKLEQQQAAQERLLAAQLDAAFRQGEHTGLQlilsg 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1230 EESQRLSWLRAQVQSSTQADEDQIraeqeASLQKLREELeSQQKAErasLEQKNRQMLEQLKEEIEASEKSEQA------ 1303
Cdd:PRK11637   149 EESQRGERILAYFGYLNQARQETI-----AELKQTREEL-AAQKAE---LEEKQSQQKTLLYEQQAQQQKLEQArnerkk 219

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462523724 1304 ---ALNAAKEKALQQLRE--QLEGERKEAVATLEKEHSAELERlcsslEAKHREVVsslQKKIQEAQQK 1367
Cdd:PRK11637   220 tltGLESSLQKDQQQLSElrANESRLRDSIARAEREAKARAER-----EAREAARV---RDKQKQAKRK 280

GumC

COG3206

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

1268-1549

3.13e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 49.24 E-value: 3.13e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1268 LESQQKAERASLEQKNRQMLEQLKEeieASEKSEQAalnaakEKALQQLREQlegerkEAVATLEKEHSAELERLcSSLE 1347
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPE---LRKELEEA------EAALEEFRQK------NGLVDLSEEAKLLLQQL-SELE 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1348 AKHREvvssLQKKIQEAQQKEEaQLQKCLGQVEHRVHQKSyhvagyEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVM 1427
Cdd:COG3206    226 SQLAE----ARAELAEAEARLA-ALRAQLGSGPDALPELL------QSPVIQQLRAQLAELEAELAELSARYTPNHPDVI 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1428 AKareqyeaeeRKQRAELLGHLTGELERLQRAHERELETVRQeqhkRLEDLRRRHREQERKLQDLeldletrakdvkarl 1507
Cdd:COG3206    295 AL---------RAQIAALRAQLQQEAQRILASLEAELEALQA----REASLQAQLAQLEARLAEL--------------- 346

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2462523724 1508 allevqeetARREkQQLLDVQRQVALKSEEATATHQQLEEAQ 1549
Cdd:COG3206    347 ---------PELE-AELRRLEREVEVARELYESLLQRLEEAR 378

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1161-1772

3.33e-05

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.20 E-value: 3.33e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1161 EEAVAQVLEQDQRHLLESKQEKMQQLREKLcQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMreeeSQRLSWLRA 1240
Cdd:pfam02463  234 LNEERIDLLQELLRDEQEEIESSKQEIEKE-EEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK----SELLKLERR 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1241 QVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEqknRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQL 1320
Cdd:pfam02463  309 KVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELE---IKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1321 EGERKEAV-------------ATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKs 1387
Cdd:pfam02463  386 LSSAAKLKeeelelkseeekeAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDE- 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1388 yhvagYEHELSSLLREKRQEVEGE--HERRLDKMKEEHQQVMA-KAREQYEAEERKQRAELLGHLTGELERLQRAHERE- 1463
Cdd:pfam02463  465 -----LELKKSEDLLKETQLVKLQeqLELLLSRQKLEERSQKEsKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVe 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1464 --------LETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQE--ETARREKQQLLDVQRQVAL 1533
Cdd:pfam02463  540 nykvaistAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidPILNLAQLDKATLEADEDD 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1534 KSEEATATHQQLEEAQKEHTHLLQSNQQLREI--LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREV 1611
Cdd:pfam02463  620 KRAKVVEGILKDTELTKLKESAKAKESGLRKGvsLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQL 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1612 TVEENNASPHFEP-DLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSA-EGVALRSAKEFLVQQTRSM 1689
Cdd:pfam02463  700 EIKKKEQREKEELkKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKeEKEEEKSELSLKEKELAEE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1690 RRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEA 1769
Cdd:pfam02463  780 REKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERL 859


                   ...
gi 2462523724 1770 SDE 1772
Cdd:pfam02463  860 EEE 862

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1150-1477

3.74e-05

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.90 E-value: 3.74e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1150 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAieEEEARMRE 1229
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA--EEELAEAE 781

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1230 EESQRLSWLRAQVQSSTQADEDQIRAEQEA------SLQKLREELESQQKAERAS------LEQKNRQMLEQLkEEIEAS 1297
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAEltllneEAANLRERLESLERRIAATerrledLEEQIEELSEDI-ESLAAE 860

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1298 EKSEQAALNAAKE--KALQQLREQLEGERKEAVATLEK------EHSAELERLCSSLEAKhREVVSSLQKKIQEAQQKEE 1369
Cdd:TIGR02168  861 IEELEELIEELESelEALLNERASLEEALALLRSELEElseelrELESKRSELRRELEEL-REKLAQLELRLEGLEVRID 939

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1370 AQLQKC--LGQVEHRVHQKSYhvagyehelssllrEKRQEVEGEHERRLDKMKEEHQQ---VMAKAREQYEAEErkqraE 1444
Cdd:TIGR02168  940 NLQERLseEYSLTLEEAEALE--------------NKIEDDEEEARRRLKRLENKIKElgpVNLAAIEEYEELK-----E 1000

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 2462523724 1445 LLGHLTGELERLQRAHERELETVRQ---EQHKRLED 1477
Cdd:TIGR02168 1001 RYDFLTAQKEDLTEAKETLEEAIEEidrEARERFKD 1036

Mplasa_alph_rch

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

1234-1765

4.13e-05

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 48.86 E-value: 4.13e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1234 RLSWLRAQVQSSTQADEDQIR--AEQEASLQKLREELESQQKA------ERASLEQKnrqmLEQLKEEIEaSEKSEQAAL 1305
Cdd:TIGR04523  146 EIKKKEKELEKLNNKYNDLKKqkEELENELNLLEKEKLNIQKNidkiknKLLKLELL----LSNLKKKIQ-KNKSLESQI 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1306 NAAKEKAlQQLREQLEGERKEAVATLEKEHSAElERLcSSLEAKHREVVSSLQKKIQEAQQKEeaqlqKCLGQVEHRVHQ 1385
Cdd:TIGR04523  221 SELKKQN-NQLKDNIEKKQQEINEKTTEISNTQ-TQL-NQLKDEQNKIKKQLSEKQKELEQNN-----KKIKELEKQLNQ 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1386 ksyhvagYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEA-----EERKQRAELLGHLTGELERLQRah 1460
Cdd:TIGR04523  293 -------LKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIisqlnEQISQLKKELTNSESENSEKQR-- 363

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1461 erELEtvrqEQHKRLEDLRRrhrEQERKLQDLElDLETRAKDVKARLallEVQEETARREKQQLLDVQRQVALKSEEATA 1540
Cdd:TIGR04523  364 --ELE----EKQNEIEKLKK---ENQSYKQEIK-NLESQINDLESKI---QNQEKLNQQKDEQIKKLQQEKELLEKEIER 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1541 THQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVT-----VEE 1615
Cdd:TIGR04523  431 LKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNeekkeLEE 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1616 NNASPHFEPDLHIEDLRKSlgTNQTKEVSSSLSQSKEDLylDSLSSHNVWHLLsaEGVALRSAKEfLVQqtrsMRRRQTA 1695
Cdd:TIGR04523  511 KVKDLTKKISSLKEKIEKL--ESEKKEKESKISDLEDEL--NKDDFELKKENL--EKEIDEKNKE-IEE----LKQTQKS 579

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1696 LKAAQQHwrhelasAQEVAKDppgikaLEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSL 1765
Cdd:TIGR04523  580 LKKKQEE-------KQELIDQ------KEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNI 636

mukB

chromosome partition protein MukB;

1171-1610

4.21e-05

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 48.80 E-value: 4.21e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1171 DQRHLLESKQEKMQQLREklcqeeeeeiLRLHQQKEQSLSSLRERLQKaieeeearmreeesqrlswlRAQVQSSTQADE 1250
Cdd:PRK04863   507 EQRHLAEQLQQLRMRLSE----------LEQRLRQQQRAERLLAEFCK--------------------RLGKNLDDEDEL 556

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1251 DQIRAEQEASLQKLREELESQqkAERASLEqknRQMLEQLKEEIEASEKSEQAALNAakEKALQQLREQLEGERKEAVA- 1329
Cdd:PRK04863   557 EQLQEELEARLESLSESVSEA--RERRMAL---RQQLEQLQARIQRLAARAPAWLAA--QDALARLREQSGEEFEDSQDv 629

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1330 ------TLEKEHSAELERlcSSLEAKHRevvsSLQKKIQEAQQKEEAQLQKCLGQVEH-------------RVHQKSYHV 1390
Cdd:PRK04863   630 teymqqLLERERELTVER--DELAARKQ----ALDEEIERLSQPGGSEDPRLNALAERfggvllseiyddvSLEDAPYFS 703

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1391 AGY--------------------------------EHELSSLlREKRQEVE----------GEHERRLDKMKEEhqQVMA 1428
Cdd:PRK04863   704 ALYgparhaivvpdlsdaaeqlagledcpedlyliEGDPDSF-DDSVFSVEelekavvvkiADRQWRYSRFPEV--PLFG 780

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1429 K-AREQYEAE---ERKQRAELLGHLTGELERLQRAHERELETVRQ--------EQHKRLEDLRRRHREQERKLQDLE--- 1493
Cdd:PRK04863   781 RaAREKRIEQlraEREELAERYATLSFDVQKLQRLHQAFSRFIGShlavafeaDPEAELRQLNRRRVELERALADHEsqe 860

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1494 LDLETRAKDVKARLALL--------------------EVQEETARRE--------------------------------- 1520
Cdd:PRK04863   861 QQQRSQLEQAKEGLSALnrllprlnlladetladrveEIREQLDEAEeakrfvqqhgnalaqlepivsvlqsdpeqfeql 940

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1521 -------KQQLLDVQRQV-ALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQK 1592
Cdd:PRK04863   941 kqdyqqaQQTQRDAKQQAfALTEVVQRRAHFSYEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQ 1020

                          570
                   ....*....|....*...
gi 2462523724 1593 HFSSLEAEAQKKQHLLRE 1610
Cdd:PRK04863  1021 VLASLKSSYDAKRQMLQE 1038

smart00456

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...

57-87

4.29e-05

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.

Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 42.20 E-value: 4.29e-05

                            10        20        30
                    ....*....|....*....|....*....|.
gi 2462523724    57 PLPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:smart00456    1 PLPPGWEERKDPDGRPYYYNHETKETQWEKP 31

AtpF

COG0711

FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]; FoF1-type ...

1247-1319

4.59e-05

FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit b or b' is part of the Pathway/BioSystem: FoF1-type ATP synthase

Pssm-ID: 440475 [Multi-domain] Cd Length: 152 Bit Score: 45.55 E-value: 4.59e-05

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462523724 1247 QADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQ 1319
Cdd:COG0711     47 KEEAEAALAEYEEKLAEARAEAAEIIAEARKEAEAIAEEAKAEAEAEAERIIAQAEAEIEQERAKALAELRAE 119

Filament

pfam00038

Intermediate filament protein;

1251-1539

5.11e-05

Intermediate filament protein;

Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 47.61 E-value: 5.11e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1251 DQIRA--EQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKsEQAALNAAKEKA---LQQLREQLE---G 1322
Cdd:pfam00038   18 DKVRFleQQNKLLETKISELRQKKGAEPSRLYSLYEKEIEDLRRQLDTLTV-ERARLQLELDNLrlaAEDFRQKYEdelN 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1323 ERKEA---VATLEKE-HSAELERLcssleakhrevvsSLQKKIQEAQqkEEAQLQKCLGQVEHRvhqksyhvagyehELS 1398
Cdd:pfam00038   97 LRTSAendLVGLRKDlDEATLARV-------------DLEAKIESLK--EELAFLKKNHEEEVR-------------ELQ 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1399 SLLREKRQEVEGEHERRLDKmkeehQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKrLEDL 1478
Cdd:pfam00038  149 AQVSDTQVNVEMDAARKLDL-----TSALAEIRAQYEEIAAKNREEAEEWYQSKLEELQQAAARNGDALRSAKEE-ITEL 222

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1479 RRR----------HREQ----ERKLQDLELDLETRAKDVKARLALLEVQ-----EETAR--REKQQLLDVqrQVALKSEE 1537
Cdd:pfam00038  223 RRTiqsleielqsLKKQkaslERQLAETEERYELQLADYQELISELEAElqetrQEMARqlREYQELLNV--KLALDIEI 300


                   ..
gi 2462523724 1538 AT 1539
Cdd:pfam00038  301 AT 302

HCR

pfam07111

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...

1267-1573

5.29e-05

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.

Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 48.21 E-value: 5.29e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1267 ELESQQKAERASLEQKNRQMLEqLKEEIeASEKSEQAALnaakEKALQQLREQLEGERKEAVA-TLEKEHSAELER---- 1341
Cdd:pfam07111  321 QLKAQDLEHRDSVKQLRGQVAE-LQEQV-TSQSQEQAIL----QRALQDKAAEVEVERMSAKGlQMELSRAQEARRrqqq 394

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1342 LCSSLEAKHREVVSSLqKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYeHELSSLLREK------RQE-------- 1407
Cdd:pfam07111  395 QTASAEEQLKFVVNAM-SSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKV-HTIKGLMARKvalaqlRQEscpppppa 472

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1408 --VEGEHERRLDKMKEEH--------------QQVMAKAREQYEAEeRKQRAELLGHLTGELERLQRAHE---RELETVR 1468
Cdd:pfam07111  473 ppVDADLSLELEQLREERnrldaelqlsahliQQEVGRAREQGEAE-RQQLSEVAQQLEQELQRAQESLAsvgQQLEVAR 551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1469 QEQHKRLED---LRRRHREQE----RKLQDLELDLETRAKDvkaRLALLEVQEETARREKQQLLDVQRQVALKSEEATAT 1541
Cdd:pfam07111  552 QGQQESTEEaasLRQELTQQQeiygQALQEKVAEVETRLRE---QLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKER 628

                          330       340       350
                   ....*....|....*....|....*....|..
gi 2462523724 1542 HQQLEEAQKEHTHllQSNQQLREILDELQARK 1573
Cdd:pfam07111  629 NQELRRLQDEARK--EEGQRLARRVQELERDK 658

PspA

COG1842

Phage shock protein A [Transcription, Signal transduction mechanisms];

1251-1370

5.36e-05

Phage shock protein A [Transcription, Signal transduction mechanisms];

Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 46.36 E-value: 5.36e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1251 DQIRAEQEASLQKLREELeSQQKAERASLEQKnrqmLEQLKEEIEASEKSEQAALNAAKE----KALQQlREQLEGERKE 1326
Cdd:COG1842     29 DQAIRDMEEDLVEARQAL-AQVIANQKRLERQ----LEELEAEAEKWEEKARLALEKGREdlarEALER-KAELEAQAEA 102

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2462523724 1327 AVATLEkEHSAELERLcssleakhREVVSSLQKKIQEAQQKEEA 1370
Cdd:COG1842    103 LEAQLA-QLEEQVEKL--------KEALRQLESKLEELKAKKDT 137

DUF4670

pfam15709

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

1244-1444

5.45e-05

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 48.02 E-value: 5.45e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1244 SSTQADEDQIRAEQeASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE 1323
Cdd:pfam15709  329 EQEKASRDRLRAER-AEMRRLEVERKRREQEEQRRLQQEQLERAEKMREELELEQQRRFEEIRLRKQRLEEERQRQEEEE 407

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1324 RKEAVatlekEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgqvehrvhqksyhvagyehelssllRE 1403
Cdd:pfam15709  408 RKQRL-----QLQAAQERARQQQEEFRRKLQELQRKKQQEEAERAEAEKQ----------------------------RQ 454

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462523724 1404 KRQEVE-GEHERRLDKMKEEH------QQVMAKAREQYEAEERKQRAE 1444
Cdd:pfam15709  455 KELEMQlAEEQKRLMEMAEEErleyqrQKQEAEEKARLEAEERRQKEE 502

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

1233-1603

6.53e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 48.19 E-value: 6.53e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1233 QRLSWLRAQVQSSTQADEDQiraeQEASLQKLREELE--SQQKAERASLEQKNRQMLEQL---KEEIEASEK--SEQAAL 1305
Cdd:pfam15921  429 QRLEALLKAMKSECQGQMER----QMAAIQGKNESLEkvSSLTAQLESTKEMLRKVVEELtakKMTLESSERtvSDLTAS 504

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1306 NAAKEKALQQLREQLEGERKEAVATL--------EKEHSAELERLCSSLE---AKHREVVSSLQKKIQE----------- 1363
Cdd:pfam15921  505 LQEKERAIEATNAEITKLRSRVDLKLqelqhlknEGDHLRNVQTECEALKlqmAEKDKVIEILRQQIENmtqlvgqhgrt 584

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1364 --AQQKEEAQLQKCLGqvEHRVHQKSYHVagyehelsslLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEA--EER 1439
Cdd:pfam15921  585 agAMQVEKAQLEKEIN--DRRLELQEFKI----------LKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAvkDIK 652

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1440 KQRAELLGHLtgelerlqRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARR 1519
Cdd:pfam15921  653 QERDQLLNEV--------KTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGH 724

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1520 EKQQLLDVQRQVALKSEEATATH---QQLEE----AQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQK 1592
Cdd:pfam15921  725 AMKVAMGMQKQITAKRGQIDALQskiQFLEEamtnANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKE 804

                          410
                   ....*....|.
gi 2462523724 1593 HFSSLEAEAQK 1603
Cdd:pfam15921  805 KVANMEVALDK 815

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

1251-1444

7.57e-05

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 48.29 E-value: 7.57e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1251 DQIRAEQEASLQ--KLREELESQQKAERASLEQK----NRQMLEQLKEEIEASEKSEQAALNAAKEKAL----QQLREQL 1320
Cdd:NF012221  1532 DNVVATSESSQQadAVSKHAKQDDAAQNALADKEraeaDRQRLEQEKQQQLAAISGSQSQLESTDQNALetngQAQRDAI 1611

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1321 EGERKEAVATLEK------------EHSAEL---------ERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgQV 1379
Cdd:NF012221  1612 LEESRAVTKELTTlaqgldaldsqaTYAGESgdqwrnpfaGGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQ----KV 1687

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462523724 1380 EHRVHQKSYHVA-GYEHELSSLLREKRQEVEGEhERRLDKMKEEHQQVMAKAREQYEAEERKQRAE 1444
Cdd:NF012221  1688 KDAVAKSEAGVAqGEQNQANAEQDIDDAKADAE-KRKDDALAKQNEAQQAESDANAAANDAQSRGE 1752

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

1424-1553

7.98e-05

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 47.90 E-value: 7.98e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1424 QQVMAKAREQYEAEERK-----QRAEllghltgELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLEt 1498
Cdd:PRK00409   501 ENIIEEAKKLIGEDKEKlneliASLE-------ELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAE- 572

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462523724 1499 rakdVKARLALLEVQEETARREKQ-QLLDVQRQVALKSEEATATHQQLEEAQKEHT 1553
Cdd:PRK00409   573 ----KEAQQAIKEAKKEADEIIKElRQLQKGGYASVKAHELIEARKRLNKANEKKE 624

Cast

pfam10174

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...

1171-1530

8.85e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.

Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.51 E-value: 8.85e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1171 DQRHLLESKQEKMQQLREKlcqeeeeeILRLHQQ---KEQSLSSLRERLQKaieeeearmreeesqrlswlrAQVQSSTQ 1247
Cdd:pfam10174  384 DLKDMLDVKERKINVLQKK--------IENLQEQlrdKDKQLAGLKERVKS---------------------LQTDSSNT 434

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1248 ----ADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQmLEQLKEEIEAS--EKSEQ-AALNAAKEKA-------- 1312
Cdd:pfam10174  435 dtalTTLEEALSEKERIIERLKEQREREDRERLEELESLKKE-NKDLKEKVSALqpELTEKeSSLIDLKEHAsslassgl 513

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1313 -----LQQLREQLEGERKEAVAT---LEKEHSAEL-ERLCSSLEAKHREVVSSLQKKIQEAQ--QKEEAQLQKCLGQVEH 1381
Cdd:pfam10174  514 kkdskLKSLEIAVEQKKEECSKLenqLKKAHNAEEaVRTNPEINDRIRLLEQEVARYKEESGkaQAEVERLLGILREVEN 593

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1382 RVHQKSYHVAgyEHELSSLLREKRQEVEGEHERRLDK-MKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERL---- 1456
Cdd:pfam10174  594 EKNDKDKKIA--ELESLTLRQMKEQNKKVANIKHGQQeMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTrqel 671

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1457 -----------QRAHERE--LETVRQEqhkrledlRRRHREQERKLQDLELDLETRAKDvkARLALLEV--------QEE 1515
Cdd:pfam10174  672 datkarlsstqQSLAEKDghLTNLRAE--------RRKQLEEILEMKQEALLAAISEKD--ANIALLELssskkkktQEE 741

                          410
                   ....*....|....*..
gi 2462523724 1516 TA--RREKQQLLDVQRQ 1530
Cdd:pfam10174  742 VMalKREKDRLVHQLKQ 758

COG4995

Uncharacterized conserved protein, contains CHAT domain [Function unknown];

1163-1580

1.05e-04

Uncharacterized conserved protein, contains CHAT domain [Function unknown];

Pssm-ID: 444019 [Multi-domain] Cd Length: 711 Bit Score: 47.27 E-value: 1.05e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1163 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQV 1242
Cdd:COG4995     12 ALLAALALALLALALLLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALALAALALALLA 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1243 QSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAkEKALQQLREQLEG 1322
Cdd:COG4995     92 AALALALAAAALAALALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAA-AAAAAAALLALAL 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1323 ERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR 1402
Cdd:COG4995    171 ALAAAALALLALLLAALAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALLALAAAAAAL 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1403 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELET----VRQEQHKRLEDL 1478
Cdd:COG4995    251 AAAAAALLALAAALLLLAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAAlallLLAALLLLLAAL 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1479 RRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQ----VALKSEEATATHQQLEEAQKEHTH 1554
Cdd:COG4995    331 ALLALLLLLAAAALLAAALAAALALAAALALALLAALLLLLAALLALLLEALllllLALLAALLLLAAALLALAAAQLLR 410

                          410       420
                   ....*....|....*....|....*.
gi 2462523724 1555 LLQSNQQLREILDELQARKLKLESQV 1580
Cdd:COG4995    411 LLLAALALLLALAAYAAARLALLALI 436

Cast

pfam10174

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...

1235-1761

1.14e-04

Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.12 E-value: 1.14e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1235 LSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQqkaerasLEQKNRQMLeQLKEEIEaseKSEQAALNAAKEKALQ 1314
Cdd:pfam10174  164 LEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVL-------LDQKEKENI-HLREELH---RRNQLQPDPAKTKALQ 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1315 QLREQLE---GERKEAVATLEKE-----HSAELERLCSSLEAKHREVVSSLQK----KIQEAQQ---KEEAQLQKCLGQV 1379
Cdd:pfam10174  233 TVIEMKDtkiSSLERNIRDLEDEvqmlkTNGLLHTEDREEEIKQMEVYKSHSKfmknKIDQLKQelsKKESELLALQTKL 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1380 EHRVHQKS---YHVAGYEHELSSllREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYE--AEERkqraellGHLTGELE 1454
Cdd:pfam10174  313 ETLTNQNSdckQHIEVLKESLTA--KEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQdlTEEK-------STLAGEIR 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1455 RLQR---AHERELETVrqeqHKRLEDLRRRHREQERKLQDLE---LDLETRAKDVKARLALLEvqeeTARREKQQLLDvq 1528
Cdd:pfam10174  384 DLKDmldVKERKINVL----QKKIENLQEQLRDKDKQLAGLKervKSLQTDSSNTDTALTTLE----EALSEKERIIE-- 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1529 rqvALKSEEATATHQQLEEAQKehthLLQSNQQLREILDELQARKLKLES-------QVDLLQAQSQQLQKHFSSLEAEA 1601
Cdd:pfam10174  454 ---RLKEQREREDRERLEELES----LKKENKDLKEKVSALQPELTEKESslidlkeHASSLASSGLKKDSKLKSLEIAV 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1602 QKK---------QHLLREVTVEENNASPHFepDLHIEDLRKSLGTNQTKevsSSLSQSKEDLYLDSLSSHNVWHLLSAEG 1672
Cdd:pfam10174  527 EQKkeecsklenQLKKAHNAEEAVRTNPEI--NDRIRLLEQEVARYKEE---SGKAQAEVERLLGILREVENEKNDKDKK 601

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1673 VAlrSAKEFLVQQTRSMRRRQTALKAAQQHWRHELAS-------AQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR 1745
Cdd:pfam10174  602 IA--ELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQlleearrREDNLADNSQQLQLEELMGALEKTRQELDATKARLS 679

                          570
                   ....*....|....*.
gi 2462523724 1746 KGHNLLKKKEEKLNQL 1761
Cdd:pfam10174  680 STQQSLAEKDGHLTNL 695

mukB

chromosome partition protein MukB;

1238-1581

1.18e-04

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 47.64 E-value: 1.18e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1238 LRAQVQSStqadEDQIRAEQEAsLQKLREELEsQQKAERASLEQKNRQMLEQLKEEIEA---SEKSEQAalnaakEKALQ 1314
Cdd:PRK04863   291 LRRELYTS----RRQLAAEQYR-LVEMARELA-ELNEAESDLEQDYQAASDHLNLVQTAlrqQEKIERY------QADLE 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1315 QLREQLEgERKEAVAtLEKEHSAELERLCSSLEakhrEVVSSLQKKIQEAQQKEEAQlQKCLGQVEHRVH-----QKSYH 1389
Cdd:PRK04863   359 ELEERLE-EQNEVVE-EADEQQEENEARAEAAE----EEVDELKSQLADYQQALDVQ-QTRAIQYQQAVQaleraKQLCG 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1390 VAGYEHE-LSSLLREKRQEVEGEHERRLDKmkeEHQQVMAK-AREQYEaeerkQRAELLGHLTGELERlQRAHERELETV 1467
Cdd:PRK04863   432 LPDLTADnAEDWLEEFQAKEQEATEELLSL---EQKLSVAQaAHSQFE-----QAYQLVRKIAGEVSR-SEAWDVARELL 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1468 RQ-EQHK----RLEDLRRRHREQERKLQdLELDLETRAKDVKARLAL-----LEVQEETARREkQQLLDVQRQVALKSEE 1537
Cdd:PRK04863   503 RRlREQRhlaeQLQQLRMRLSELEQRLR-QQQRAERLLAEFCKRLGKnlddeDELEQLQEELE-ARLESLSESVSEARER 580

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 2462523724 1538 ATATHQQLEEaqkehthllqsnqqlreildelqarklkLESQVD 1581
Cdd:PRK04863   581 RMALRQQLEQ----------------------------LQARIQ 596

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

1397-1551

1.43e-04

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 46.40 E-value: 1.43e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1397 LSSLLREKRQEV-EGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRaellghltgELERLQRAH-ERELETVRQEQHKR 1474
Cdd:COG2268    186 LDALGRRKIAEIiRDARIAEAEAERETEIAIAQANREAEEAELEQER---------EIETARIAEaEAELAKKKAEERRE 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1475 LEDLRRR-----HREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLL--DVQRQVALKSEEATATHQQlEE 1547
Cdd:COG2268    257 AETARAEaeaayEIAEANAEREVQRQLEIAEREREIELQEKEAEREEAELEADVRKpaEAEKQAAEAEAEAEAEAIR-AK 335


                   ....
gi 2462523724 1548 AQKE 1551
Cdd:COG2268    336 GLAE 339

PHA03307

transcriptional regulator ICP4; Provisional

823-1173

1.59e-04

transcriptional regulator ICP4; Provisional

Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.09 E-value: 1.59e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  823 SQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAvgkgRQGSGARPGLPEKEENEKSEPKicRNLVTPKADPTGSEPA 902
Cdd:PHA03307    45 SDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAP----ANESRSTPTWSLSTLAPASPAR--EGSPTPPGPSSPDPPP 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  903 KASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEleiSEHMKEPQLSDSIASDPKSFHGL-----DFGF 977
Cdd:PHA03307   119 PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVA---SDAASSRQAALPLSSPEETARAPssppaEPPP 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  978 RSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERyHRLSPPLPHEERAQSPPRSLATEE 1057
Cdd:PHA03307   196 STPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWG-PENECPLPRPAPITLPTRIWEASG 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1058 EPPQGPEGQPEWKEAEELGEDSAAS--------LSLQLSLQREQAPSPPAACEKGKEQHSQAEELG--PGQEEAEDPEEK 1127
Cdd:PHA03307   275 WNGPSSRPGPASSSSSPRERSPSPSpsspgsgpAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAvsPGPSPSRSPSPS 354

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 2462523724 1128 VAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQR 1173
Cdd:PHA03307   355 RPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARR 400

Caldesmon

pfam02029

Caldesmon;

1249-1559

1.72e-04

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 46.40 E-value: 1.72e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1249 DEDQIRAEQEASlQKLREELESQQKAERASLEQKNRQMLEQ---------LKEEIEASEKSEQAALN---AAKEKALQQL 1316
Cdd:pfam02029    1 IEDEEEAARERR-RRAREERRRQKEEEEPSGQVTESVEPNEhnsyeedseLKPSGQGGLDEEEAFLDrtaKREERRQKRL 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1317 REQLEGE----------------RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQlqkclgQVE 1380
Cdd:pfam02029   80 QEALERQkefdptiadekesvaeRKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVR------QAE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1381 HRVHQKSYHVAgyEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAkaREQYEAEERKQRAELLGHLTGELERLQRAH 1460
Cdd:pfam02029  154 EEGEEEEDKSE--EAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLD--QKRGHPEVKSQNGEEEVTKLKVTTKRRQGG 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1461 ERELETVRQEQH------KRLEDLRRRHREQER--------KLQDLELDLETRAKDVKARLALLEvqEETARREKQQLld 1526
Cdd:pfam02029  230 LSQSQEREEEAEvfleaeQKLEELRRRRQEKESeefeklrqKQQEAELELEELKKKREERRKLLE--EEEQRRKQEEA-- 305

                          330       340       350
                   ....*....|....*....|....*....|...
gi 2462523724 1527 vQRQVAlKSEEATATHQQLEEAQKEHTHLLQSN 1559
Cdd:pfam02029  306 -ERKLR-EEEEKRRMKEEIERRRAEAAEKRQKL 336

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

1357-1528

2.08e-04

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 45.65 E-value: 2.08e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1357 LQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV-AGY------------------------EHELSSLLREKrqEVEGE 1411
Cdd:cd16269    107 CKQNEEASSKRCQALLQELSAPLEEKISQGSYSVpGGYqlyledreklvekyrqvprkgvkaEEVLQEFLQSK--EAEAE 184

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1412 HERRLDKMKEEHQQVMAKAREQYEAEErkQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQD 1491
Cdd:cd16269    185 AILQADQALTEKEKEIEAERAKAEAAE--QERKLLEEQQRELEQKLEDQERSYEEHLRQLKEKMEEERENLLKEQERALE 262

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2462523724 1492 LELDLETRakdvkarlALLEVQEETARREKQQLLDVQ 1528
Cdd:cd16269    263 SKLKEQEA--------LLEEGFKEQAELLQEEIRSLK 291

Mplasa_alph_rch

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

1168-1504

2.27e-04

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 46.17 E-value: 2.27e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1168 LEQDQRHLLESKQEKMQQLREKlcQEEEEEILRLHQQKEQSLSSLRERLQKaieeeearmreeesqrlswLRAQVQSSTQ 1247
Cdd:TIGR04523  347 LKKELTNSESENSEKQRELEEK--QNEIEKLKKENQSYKQEIKNLESQIND-------------------LESKIQNQEK 405

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1248 adEDQIRAEQEASLQKLREELESQQKAERASLEqKNRQMLEQLKEEIEASEKsEQAALNAAKEKALQQLrEQLEGERKEA 1327
Cdd:TIGR04523  406 --LNQQKDEQIKKLQQEKELLEKEIERLKETII-KNNSEIKDLTNQDSVKEL-IIKNLDNTRESLETQL-KVLSRSINKI 480

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1328 VATLEKEhSAELERLCSSLEAKHREV------VSSLQKKIQEAQQKEEaQLQKCLGQVEHRVHQKsyhvagyEHELSS-- 1399
Cdd:TIGR04523  481 KQNLEQK-QKELKSKEKELKKLNEEKkeleekVKDLTKKISSLKEKIE-KLESEKKEKESKISDL-------EDELNKdd 551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1400 --LLREKRQEVEGEHERRLDKMKEEHQQVMAKARE------QYEAEERKQRAELLghltgELERLQRAHERELETVRQEq 1471
Cdd:TIGR04523  552 feLKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEkqelidQKEKEKKDLIKEIE-----EKEKKISSLEKELEKAKKE- 625

                          330       340       350
                   ....*....|....*....|....*....|...
gi 2462523724 1472 HKRLEdlrrrhrEQERKLQDLELDLETRAKDVK 1504
Cdd:TIGR04523  626 NEKLS-------SIIKNIKSKKNKLKQEVKQIK 651

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1348-1524

2.39e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.92 E-value: 2.39e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1348 AKHREVVSSLQKKIQEAQQkEEAQLQKCLGQVEHRVHqksyhvagyehELSSLLREKRQEVEgEHERRLDKMKEehQQVM 1427
Cdd:COG1579     20 DRLEHRLKELPAELAELED-ELAALEARLEAAKTELE-----------DLEKEIKRLELEIE-EVEARIKKYEE--QLGN 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1428 AKAREQYEAeerkqraellghLTGELERLQRAHErELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARL 1507
Cdd:COG1579     85 VRNNKEYEA------------LQKEIESLKRRIS-DLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEEL 151

                          170
                   ....*....|....*..
gi 2462523724 1508 ALLEVQEETARREKQQL 1524
Cdd:COG1579    152 AELEAELEELEAEREEL 168

GumC

COG3206

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

1397-1578

3.46e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.78 E-value: 3.46e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1397 LSSLLREKRQEVEgEHERRLDKMKEEHQQVMAKAREQYEAEE----RKQRAELLGHLTgELERLQRAHERELETVRQE-- 1470
Cdd:COG3206    180 LEEQLPELRKELE-EAEAALEEFRQKNGLVDLSEEAKLLLQQlselESQLAEARAELA-EAEARLAALRAQLGSGPDAlp 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1471 ---QHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLL-DVQRQVALKSEEATATHQQLE 1546
Cdd:COG3206    258 ellQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILaSLEAELEALQAREASLQAQLA 337

                          170       180       190
                   ....*....|....*....|....*....|..
gi 2462523724 1547 EAQKEHTHLLQSNQQLREILDELQARKLKLES 1578
Cdd:COG3206    338 QLEARLAELPELEAELRRLEREVEVARELYES 369

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1065-1353

3.52e-04

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.83 E-value: 3.52e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1065 GQPEWKEAEELgEDSAASLSlQLSLQREQAPSPPAACEKGKEQhsQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTE 1144
Cdd:TIGR02169  729 EQEEEKLKERL-EELEEDLS-SLEQEIENVKSELKELEARIEE--LEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLE 804

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1145 pvappEQLS--EAALKAMEEAVaQVLEQDQRHLLESKQEKMQQLRE------KLCQEEEEEILRL---------HQQKEQ 1207
Cdd:TIGR02169  805 -----EEVSriEARLREIEQKL-NRLTLEKEYLEKEIQELQEQRIDlkeqikSIEKEIENLNGKKeeleeeleeLEAALR 878

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1208 SLSSLRERLQKAIEEEEARMREEEsQRLSWLRAQVQsstqaDEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM- 1286
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELE-RKIEELEAQIE-----KKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELs 952

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462523724 1287 LEQLKEEIEASEKsEQAALNAAKEKALQQLREQLE--GERKEAVATLEKEHSAELERLcSSLEAKHREV 1353
Cdd:TIGR02169  953 LEDVQAELQRVEE-EIRALEPVNMLAIQEYEEVLKrlDELKEKRAKLEEERKAILERI-EEYEKKKREV 1019

PRK12704

phosphodiesterase; Provisional

1344-1551

3.55e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.54 E-value: 3.55e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1344 SSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHqksyhvagyehelssllrEKRQEVEGEHERRLDKMKEEH 1423
Cdd:PRK12704    27 KIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIH------------------KLRNEFEKELRERRNELQKLE 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1424 QQVMAKareqyeaEER-KQRAELLGHLTGELErlqrAHERELETVRQEQHKRLEDLRRRHREQERKLQDL-ELDLEtrak 1501
Cdd:PRK12704    89 KRLLQK-------EENlDRKLELLEKREEELE----KKEKELEQKQQELEKKEEELEELIEEQLQELERIsGLTAE---- 153

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1502 dvKARLALLEVQEETARREKQQLLdvqRQValkSEEATathqqlEEAQKE 1551
Cdd:PRK12704   154 --EAKEILLEKVEEEARHEAAVLI---KEI---EEEAK------EEADKK 189

HlpA

COG2825

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ...

1262-1364

3.85e-04

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 442073 [Multi-domain] Cd Length: 171 Bit Score: 43.29 E-value: 3.85e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1262 QKLREELESQQKAERASLEQKNRQmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAvatlEKEhsaeler 1341
Cdd:COG2825     42 KAAQKKLEKEFKKRQAELQKLEKE-LQALQEKLQKEAATLSEEERQKKERELQKKQQELQRKQQEA----QQD------- 109

                           90       100
                   ....*....|....*....|...
gi 2462523724 1342 lcssLEAKHREVVSSLQKKIQEA 1364
Cdd:COG2825    110 ----LQKRQQELLQPILEKIQKA 128

DUF4659

pfam15558

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...

1157-1519

4.30e-04

Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 45.03 E-value: 4.30e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1157 LKAMEEAVAQVLEQDQRHLL----ESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKaieeeearMREEES 1232
Cdd:pfam15558   37 LRRRDQKRQETLERERRLLLqqsqEQWQAEKEQRKARLGREERRRADRREKQVIEKESRWREQAED--------QENQRQ 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1233 QRLSWLRAQVQSSTQADEDQIRaEQEASLQKLRE--ELESQQKAERASLEQKNRQMLEQLKeeIEASEKSEQAALNAAKE 1310
Cdd:pfam15558  109 EKLERARQEAEQRKQCQEQRLK-EKEEELQALREqnSLQLQERLEEACHKRQLKEREEQKK--VQENNLSELLNHQARKV 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1311 KALQQLREQLEGERKeavaTLEKEHSAELERLCSSLEAKHREvvsslqkkIQEAQQKEEAQLQKclgqvehrvhqksyhv 1390
Cdd:pfam15558  186 LVDCQAKAEELLRRL----SLEQSLQRSQENYEQLVEERHRE--------LREKAQKEEEQFQR---------------- 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1391 agyehelsslLREKRQEVEGEHERRLDKMKEEHQQVMAKAReQYEAEERKQRAELLGHLTGELERLQRAHERELEtvRQE 1470
Cdd:pfam15558  238 ----------AKWRAEEKEEERQEHKEALAELADRKIQQAR-QVAHKTVQDKAQRARELNLEREKNHHILKLKVE--KEE 304

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462523724 1471 QHKR---LEDLRRRHREQERKLQDLELDLETRAKDVKARLALLE-VQEETARR 1519
Cdd:pfam15558  305 KCHRegiKEAIKKKEQRSEQISREKEATLEEARKTARASFHMREkVREETNNR 357

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

1154-1366

4.49e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 45.71 E-value: 4.49e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1154 EAALKAMEEAVAQVleqdqrhlleSKQEKMQQLREKLCQeeeeeiLRLHQQKEQSLSSLRERLQKAieeeearmreeeSQ 1233
Cdd:COG3096    475 EKAYELVCKIAGEV----------ERSQAWQTARELLRR------YRSQQALAQRLQQLRAQLAEL------------EQ 526

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1234 RLswlRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKN----------RQMLEQLKEEIEASEKSEQA 1303
Cdd:COG3096    527 RL---RQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAaeaveqrselRQQLEQLRARIKELAARAPA 603

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1304 ALNAAkeKALQQLREQLEGERKEAVA-------TLEKEHSAELERlcSSLEAKHREvvssLQKKIQEAQQ 1366
Cdd:COG3096    604 WLAAQ--DALERLREQSGEALADSQEvtaamqqLLEREREATVER--DELAARKQA----LESQIERLSQ 665

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1250-1374

4.68e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.76 E-value: 4.68e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1250 EDQIRAEQEA--SLQKLREELESQQKAERASLEQKNRQM--------LEQLKEEIEASEKSEQAAlnaakEKALQQLREQ 1319
Cdd:COG1579     44 EARLEAAKTEleDLEKEIKRLELEIEEVEARIKKYEEQLgnvrnnkeYEALQKEIESLKRRISDL-----EDEILELMER 118

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462523724 1320 LEgERKEAVATLEKEHsAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK 1374
Cdd:COG1579    119 IE-ELEEELAELEAEL-AELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171

DUF4515

pfam14988

Domain of unknown function (DUF4515); This family of proteins is found in bacteria and ...

1416-1579

5.08e-04

Domain of unknown function (DUF4515); This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 198 and 469 amino acids in length. There are two completely conserved L residues that may be functionally important.

Pssm-ID: 405647 [Multi-domain] Cd Length: 206 Bit Score: 43.60 E-value: 5.08e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1416 LDKMKEEHQQVMAKAREQY-----EAEERKQRAEL-LGHLTGELERLQRAHERELETVRQeQHKRLEDLRRRHREQERKL 1489
Cdd:pfam14988    9 LAKKTEEKQKKIEKLWNQYvqeceEIERRRQELASrYTQQTAELQTQLLQKEKEQASLKK-ELQALRPFAKLKESQEREI 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1490 QDLELDLET--RAKDVKARLALLEVQEETARREKQ-QLLDVQRQVALKSEEATATHQQLEEAQK----EHTHLL-QSNQQ 1561
Cdd:pfam14988   88 QDLEEEKEKvrAETAEKDREAHLQFLKEKALLEKQlQELRILELGERATRELKRKAQALKLAAKqalsEFCRSIkRENRQ 167

                          170       180
                   ....*....|....*....|....*
gi 2462523724 1562 LREIL-------DELQARKLKLESQ 1579
Cdd:pfam14988  168 LQKELlqliqetQALEAIKSKLENR 192

Taxilin

pfam09728

Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ...

1266-1581

5.15e-04

Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.

Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 44.17 E-value: 5.15e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1266 EELESQQKAERASLEQKNrQMLEQLKEEIEASEKSEQAALNAAKEKA--LQQLREQLEGERKEAVATLEKehsaeLERLC 1343
Cdd:pfam09728    3 ARELMQLLNKLDSPEEKL-AALCKKYAELLEEMKRLQKDLKKLKKKQdqLQKEKDQLQSELSKAILAKSK-----LEKLC 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1344 SSLEAKHREVVSSLQKKIQEAQQKEE---AQLQKCLGQVEHRVHQKSYHVAGYEHElSSLLREKRQEVEGEHERR----- 1415
Cdd:pfam09728   77 RELQKQNKKLKEESKKLAKEEEEKRKelsEKFQSTLKDIQDKMEEKSEKNNKLREE-NEELREKLKSLIEQYELRelhfe 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1416 -LDKMKEEHQQ-VMAKAREQYEAEERKQRaellghltgelerlqrahERELETVRQEQhKRLEDLRrrhrEQERKLQD-L 1492
Cdd:pfam09728  156 kLLKTKELEVQlAEAKLQQATEEEEKKAQ------------------EKEVAKARELK-AQVQTLS----ETEKELREqL 212

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1493 ELDLEtRAKDVKARLALLEVQEETARREKQQLLDVQRQValkSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQAR 1572
Cdd:pfam09728  213 NLYVE-KFEEFQDTLNKSNEVFTTFKKEMEKMSKKIKKL---EKENLTWKRKWEKSNKALLEMAEERQKLKEELEKLQKK 288


                   ....*....
gi 2462523724 1573 KLKLESQVD 1581
Cdd:pfam09728  289 LEKLENLCR 297

OmpH

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

1262-1367

5.90e-04

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 42.19 E-value: 5.90e-04

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  1262 QKLREELESQQKAERASLEQKNRQmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKehsaeler 1341
Cdd:smart00935   17 KAAQKQLEKEFKKRQAELEKLEKE-LQKLKEKLQKDAATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQK-------- 87

                            90       100
                    ....*....|....*....|....*.
gi 2462523724  1342 lcssleaKHREVVSSLQKKIQEAQQK 1367
Cdd:smart00935   88 -------RQQEELQKILDKINKAIKE 106

CCDC22

pfam05667

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...

1246-1526

6.70e-04

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.

Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 44.63 E-value: 6.70e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1246 TQADEDQIRAEQEASLQKLREELESQQKAERasleqKNRQMLEQLKEEIEASEKSEQAALNAAKEkaLQQLREQLEGERK 1325
Cdd:pfam05667  217 AAAQEWEEEWNSQGLASRLTPEEYRKRKRTK-----LLKRIAEQLRSAALAGTEATSGASRSAQD--LAELLSSFSGSST 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1326 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKK----IQEAQQKEEAQLQKCLGQVEHRVHQksyhvagYEHELSSLL 1401
Cdd:pfam05667  290 TDTGLTKGSRFTHTEKLQFTNEAPAATSSPPTKVEteeeLQQQREEELEELQEQLEDLESSIQE-------LEKEIKKLE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1402 REKRQ-EVEGEHERRLDKMKEEHQQVMAKAREQY-EAEER--------KQRAELLGHLTGELERLQRAHERELETVRQEQ 1471
Cdd:pfam05667  363 SSIKQvEEELEELKEQNEELEKQYKVKKKTLDLLpDAEENiaklqalvDASAQRLVELAGQWEKHRVPLIEEYRALKEAK 442

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462523724 1472 HKRLEdlrrrhrEQERKLQDLEldlETRAKdvkarlaLLEVQEETARRE--KQQLLD 1526
Cdd:pfam05667  443 SNKED-------ESQRKLEEIK---ELREK-------IKEVAEEAKQKEelYKQLVA 482

Ax_dynein_light

pfam10211

Axonemal dynein light chain; Axonemal dynein light chain proteins play a dynamic role in ...

1251-1322

7.14e-04

Axonemal dynein light chain; Axonemal dynein light chain proteins play a dynamic role in flagellar and cilia motility. Eukaryotic cilia and flagella are complex organelles consisting of a core structure, the axoneme, which is composed of nine microtubule doublets forming a cylinder that surrounds a pair of central singlet microtubules. This ultra-structural arrangement seems to be one of the most stable micro-tubular assemblies known and is responsible for the flagellar and ciliary movement of a large number of organizms ranging from protozoan to mammals. This light chain interacts directly with the N-terminal half of the heavy chains.

Pssm-ID: 463000 [Multi-domain] Cd Length: 187 Bit Score: 42.56 E-value: 7.14e-04

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462523724 1251 DQIRAEQEASLQKLREELESQQKaERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKeKALQQLREQLEG 1322
Cdd:pfam10211  118 EQGKAELEKKIADLEEEKEELEK-QVAELKAKCEAIEKREEERRQAEEKKHAEEIAFLK-KTNQQLKAQLER 187

GumC

COG3206

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

1453-1617

7.75e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.62 E-value: 7.75e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1453 LERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLE-----LDLETRAKDVKARLALLEVQEETARRE------- 1520
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRqknglVDLSEEAKLLLQQLSELESQLAEARAElaeaear 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1521 ---------------------------KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQS-NQQLREILDELQAR 1572
Cdd:COG3206    242 laalraqlgsgpdalpellqspviqqlRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQlQQEAQRILASLEAE 321

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2462523724 1573 KLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENN 1617
Cdd:COG3206    322 LEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVAREL 366

PRK04778

septation ring formation regulator EzrA; Provisional

1279-1573

9.82e-04

septation ring formation regulator EzrA; Provisional

Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 44.06 E-value: 9.82e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1279 LEQKNRQMLEQLKEEIEASEKSeQAALNAAKEKaLQQLREQLEGERK---EAVATLEKEHS------AELERLCSS---L 1346
Cdd:PRK04778   117 IEEDIEQILEELQELLESEEKN-REEVEQLKDL-YRELRKSLLANRFsfgPALDELEKQLEnleeefSQFVELTESgdyV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1347 EAkhREVVSSLQKKIQEAQQKEE------AQLQKCL-GQVEhrvhqksyhvagyehELSSLLREkrQEVEGEH------E 1413
Cdd:PRK04778   195 EA--REILDQLEEELAALEQIMEeipellKELQTELpDQLQ---------------ELKAGYRE--LVEEGYHldhldiE 255

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1414 RRLDKMKEEHQQVMAkareQYEAEERKQRAELLGHLTGELERLQRAHERELETvRQEQHKRLEDLRRRHREQERKLQDLE 1493
Cdd:PRK04778   256 KEIQDLKEQIDENLA----LLEELDLDEAEEKNEEIQERIDQLYDILEREVKA-RKYVEKNSDTLPDFLEHAKEQNKELK 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1494 LDLETrakdVKARLALLEVQEETARREKQQLLDVQRQVaLKSEEATATHQ---------------QLEEAQKEHTHLLQS 1558
Cdd:PRK04778   331 EEIDR----VKQSYTLNESELESVRQLEKQLESLEKQY-DEITERIAEQEiayselqeeleeilkQLEEIEKEQEKLSEM 405

                          330
                   ....*....|....*
gi 2462523724 1559 NQQLREilDELQARK 1573
Cdd:PRK04778   406 LQGLRK--DELEARE 418

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1453-1636

1.02e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.99 E-value: 1.02e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1453 LERLQRAHER--ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDV--Q 1528
Cdd:COG1579      9 LLDLQELDSEldRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnN 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1529 RQV-ALKSEEATATHQQ--LEEAQKEHTHLLqsnQQLREILDELQARKLKLESQVDLLQaqsqqlqkhfSSLEAEAQKKQ 1605
Cdd:COG1579     89 KEYeALQKEIESLKRRIsdLEDEILELMERI---EELEEELAELEAELAELEAELEEKK----------AELDEELAELE 155

                          170       180       190
                   ....*....|....*....|....*....|...
gi 2462523724 1606 HLLREVTVEENNASPHFEPDL--HIEDLRKSLG 1636
Cdd:COG1579    156 AELEELEAEREELAAKIPPELlaLYERIRKRKN 188

OmpH

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

1288-1374

1.04e-03

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 41.42 E-value: 1.04e-03

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  1288 EQLKEEIEASEKSEQAALNAaKEKALQQLREQLEGERkeavATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQK 1367
Cdd:smart00935   17 KAAQKQLEKEFKKRQAELEK-LEKELQKLKEKLQKDA----ATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQKRQQE 91


                    ....*..
gi 2462523724  1368 EEAQLQK 1374
Cdd:smart00935   92 ELQKILD 98

PRK12705

hypothetical protein; Provisional

1393-1551

1.15e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 43.93 E-value: 1.15e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1393 YEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEllghLTGELERLQRAHEreletVRQEQH 1472
Cdd:PRK12705    27 KRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREE----LQREEERLVQKEE-----QLDARA 97

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462523724 1473 KRLEDLRRRHREQERKLQDLELDLETRAKDVKARlaLLEVQEETARREKQQLLDvQRQVALKSEEATATHQQLEEAQKE 1551
Cdd:PRK12705    98 EKLDNLENQLEEREKALSARELELEELEKQLDNE--LYRVAGLTPEQARKLLLK-LLDAELEEEKAQRVKKIEEEADLE 173

HCR

pfam07111

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...

1207-1546

1.26e-03

Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 43.97 E-value: 1.26e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1207 QSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQ---QKAERASLEQKN 1283
Cdd:pfam07111   59 QALSQQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAAlagAEMVRKNLEEGS 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1284 RQMLEqlkeEIEASEKSEQAALNAAKEKALQQLREQLEGERKeAVATLEKEHSAELERLcsSLEAKHREVvssLQKKIQE 1363
Cdd:pfam07111  139 QRELE----EIQRLHQEQLSSLTQAHEEALSSLTSKAEGLEK-SLNSLETKRAGEAKQL--AEAQKEAEL---LRKQLSK 208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1364 AQQKEEAQ------LQKCLG-QVEHRVHQKSYHVAGYEH-ELSSLLREKRQEVEGEHE---------RRLDKMKEEHQQV 1426
Cdd:pfam07111  209 TQEELEAQvtlvesLRKYVGeQVPPEVHSQTWELERQELlDTMQHLQEDRADLQATVEllqvrvqslTHMLALQEEELTR 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1427 MAKAREQYEAEERKQRAELLGH-------LTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQ---ERKLQDLELDL 1496
Cdd:pfam07111  289 KIQPSDSLEPEFPKKCRSLLNRwrekvfaLMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQEQailQRALQDKAAEV 368

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1497 ETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLE 1546
Cdd:pfam07111  369 EVERMSAKGLQMELSRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLE 418

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

1067-1507

1.32e-03

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.06 E-value: 1.32e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1067 PEWKEAEELGEDSAASLSLQLslQREQAPSPPAACEKGKEQHSQAEE-LGPGQEEAEDPEEKVAVsptppVSPEVrstEP 1145
Cdd:pfam12128  567 PEVWDGSVGGELNLYGVKLDL--KRIDVPEWAASEEELRERLDKAEEaLQSAREKQAAAEEQLVQ-----ANGEL---EK 636

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1146 VAPPEQLSEAALKAMEEAVAQ---VLEQDQRHLLES-------KQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRER 1215
Cdd:pfam12128  637 ASREETFARTALKNARLDLRRlfdEKQSEKDKKNKAlaerkdsANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEK 716

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1216 LQKaiEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKL--REELESQQKAERASLEQK------NRQML 1287
Cdd:pfam12128  717 QAY--WQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLgvDPDVIAKLKREIRTLERKieriavRRQEV 794

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1288 ---EQLKEEIEASEKSEQAALNAAKEKALQQLREQL---EGERKEAVATLEKEHSAeLERLCSSLEAKHREVVSSLQK-- 1359
Cdd:pfam12128  795 lryFDWYQETWLQRRPRLATQLSNIERAISELQQQLarlIADTKLRRAKLEMERKA-SEKQQVRLSENLRGLRCEMSKla 873

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1360 KIQEAQQKEEAQLQ--KCLGQVEHRVHQKSYHVAGYEHELS---SLLREKRQEVEGEHERRLdkMKEEHQQVMAKAREQY 1434
Cdd:pfam12128  874 TLKEDANSEQAQGSigERLAQLEDLKLKRDYLSESVKKYVEhfkNVIADHSGSGLAETWESL--REEDHYQNDKGIRLLD 951

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462523724 1435 EAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQ---DLELDLEtRAKDVKARL 1507
Cdd:pfam12128  952 YRKLVPYLEQWFDVRVPQSIMVLREQVSILGVDLTEFYDVLADFDRRIASFSRELQrevGEEAFFE-GVSESAVRI 1026

Lebercilin

pfam15619

Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ...

1356-1551

1.36e-03

Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.

Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 41.81 E-value: 1.36e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1356 SLQKKIQEAQQK-EEAQL-QKCLGQVEHRvHQKSYH-VAGYEHELSSLLREKRQEVEgeherrldKMKEEHQQVMAKARE 1432
Cdd:pfam15619   15 ELQNELAELQSKlEELRKeNRLLKRLQKR-QEKALGkYEGTESELPQLIARHNEEVR--------VLRERLRRLQEKERD 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1433 QyEAEERKQRAELLgHLTGELERLQR-AHERELETvRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLAlle 1511
Cdd:pfam15619   86 L-ERKLKEKEAELL-RLRDQLKRLEKlSEDKNLAE-REELQKKLEQLEAKLEDKDEKIQDLERKLELENKSFRRQLA--- 159

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2462523724 1512 vqeetarREKQQLLDVQRQVALKSEEATATHQQLEEAQKE 1551
Cdd:pfam15619  160 -------AEKKKHKEAQEEVKILQEEIERLQQKLKEKERE 192

Nop53

pfam07767

Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ...

1454-1574

1.49e-03

Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ribosomal biogenesis. They are specifically involved in the processing beyond the 27S stage of 25S rRNA maturation. This family contains sequences that bear similarity to the glioma tumour suppressor candidate region gene 2 protein (p60). This protein has been found to interact with herpes simplex type 1 regulatory proteins.

Pssm-ID: 462259 [Multi-domain] Cd Length: 353 Bit Score: 43.05 E-value: 1.49e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1454 ERLQRAHERELETVRQEQHkrLEDLRRRHREQERKLQDLELDLETRAKDVKA-RLALLEVQEETARREKQQLLDVQRQVA 1532
Cdd:pfam07767  199 ELLQKAVEAEKKRLKEEEK--LERVLEKIAESAATAEAREEKRKTKAQRNKEkRRKEEEREAKEEKALKKKLAQLERLKE 276

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 2462523724 1533 LKSEEAtathQQLEEAQKEHTHLLQSNQQLREILDELQARKL 1574
Cdd:pfam07767  277 IAKEIA----EKEKEREEKAEARKREKRKKKKEEKKLRPRKL 314

Taxilin

pfam09728

Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ...

1311-1555

1.51e-03

Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 43.02 E-value: 1.51e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1311 KALQQLREQLEGerkeaVATLEkEHSAELERLCSSLEAKHREVVSSLQKkiqeaQQKEEAQLQKCLGQVEHrvhqksyhv 1390
Cdd:pfam09728    1 KAARELMQLLNK-----LDSPE-EKLAALCKKYAELLEEMKRLQKDLKK-----LKKKQDQLQKEKDQLQS--------- 60

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1391 agyEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMakareqyeAEERKQRAELLGHLTGELErlqraherELETVRQE 1470
Cdd:pfam09728   61 ---ELSKAILAKSKLEKLCRELQKQNKKLKEESKKLA--------KEEEEKRKELSEKFQSTLK--------DIQDKMEE 121

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1471 QHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLAL--LEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEA 1548
Cdd:pfam09728  122 KSEKNNKLREENEELREKLKSLIEQYELRELHFEKLLKTkeLEVQLAEAKLQQATEEEEKKAQEKEVAKARELKAQVQTL 201


                   ....*..
gi 2462523724 1549 QKEHTHL 1555
Cdd:pfam09728  202 SETEKEL 208

dnaK

PRK00290

molecular chaperone DnaK; Provisional

1242-1371

1.59e-03

molecular chaperone DnaK; Provisional

Pssm-ID: 234715 [Multi-domain] Cd Length: 627 Bit Score: 43.55 E-value: 1.59e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1242 VQSSTQADEDQI-RAEQEASL-----QKLREELESQQKAEraSLEQKNRQMLEQLKEEIEASEKSEQaalnaakEKALQQ 1315
Cdd:PRK00290   494 ITASSGLSDEEIeRMVKDAEAnaeedKKRKELVEARNQAD--SLIYQTEKTLKELGDKVPADEKEKI-------EAAIKE 564

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462523724 1316 LREQLEGERKEAVatleKEHSAELErlcssleakhrEVVSSLQKKIQEAQQKEEAQ 1371
Cdd:PRK00290   565 LKEALKGEDKEAI----KAKTEELT-----------QASQKLGEAMYQQAQAAQGA 605

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1154-1342

1.62e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.22 E-value: 1.62e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1154 EAALKAMEEAVAQVLEQdqrhlLESKQEKMQQLREKLcqeeeEEILRLHQQKEQSLSSLRERLQkaieeeearmreeesq 1233
Cdd:COG1579     23 EHRLKELPAELAELEDE-----LAALEARLEAAKTEL-----EDLEKEIKRLELEIEEVEARIK---------------- 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1234 rlswlRAQVQSSTQADEDQIRA--EQEASLQKLREELESQQKAERASLEQKNRQmLEQLKEEIEASEK---SEQAALNAA 1308
Cdd:COG1579     77 -----KYEEQLGNVRNNKEYEAlqKEIESLKRRISDLEDEILELMERIEELEEE-LAELEAELAELEAeleEKKAELDEE 150

                          170       180       190
                   ....*....|....*....|....*....|....
gi 2462523724 1309 KEKaLQQLREQLEGERKEAVATLEKEHSAELERL 1342
Cdd:COG1579    151 LAE-LEAELEELEAEREELAAKIPPELLALYERI 183

CCCAP

pfam15964

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...

1251-1572

1.62e-03

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.

Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 43.36 E-value: 1.62e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1251 DQIRAEQEASLQKLREELESQQ--------------KAERASLEQK------NRQMLEQLKEEIEASEKSEQAALNAAKE 1310
Cdd:pfam15964  359 EQLKSELERQKERLEKELASQQekraqekealrkemKKEREELGATmlalsqNVAQLEAQVEKVTREKNSLVSQLEEAQK 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1311 KALQQ----------LREQLEG---ERKEAvatlEKEHSAELERLCSSLEAKHREV------VSSLQKKIQEAQQK---- 1367
Cdd:pfam15964  439 QLASQemdvtkvcgeMRYQLNQtkmKKDEA----EKEHREYRTKTGRQLEIKDQEIeklgleLSESKQRLEQAQQDaara 514

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1368 --EEAQLQKCLGQVEHRVHqksyhvagyeheLSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL 1445
Cdd:pfam15964  515 reECLKLTELLGESEHQLH------------LTRLEKESIQQSFSNEAKAQALQAQQREQELTQKMQQMEAQHDKTVNEQ 582

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1446 LGHLTGelerlQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLL 1525
Cdd:pfam15964  583 YSLLTS-----QNTFIAKLKEECCTLAKKLEEITQKSRSEVEQLSQEKEYLQDRLEKLQKRNEELEEQCVQHGRMHERMK 657

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 2462523724 1526 DVQRQVALKSEeatATHQQLEEAQKEHTHLLQSNQQLREILDELQAR 1572
Cdd:pfam15964  658 QRLRQLDKHCQ---ATAQQLVQLLSKQNQLFKERQNLTEEVQSLRSQ 701

DUF1978

pfam09321

Domain of unknown function (DUF1978); Members of this family are found in various hypothetical ...

1402-1579

1.72e-03

Domain of unknown function (DUF1978); Members of this family are found in various hypothetical proteins produced by the bacterium Chlamydia pneumoniae. Their exact function has not, as yet, been identified.

Pssm-ID: 312723 [Multi-domain] Cd Length: 244 Bit Score: 42.22 E-value: 1.72e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1402 REKRQEVEgEHERRLDKMKEEHQQ-VMAKAREQYEAEERKQRAELLGHLTGELER-LQRAHERELETVRQeqhkRLEDLR 1479
Cdd:pfam09321   53 RDALSEIS-RHELWEKKAHLKHLEsLYTQARDRFEKQSSKKNQKELEEAEQEYLSsWEDVKDQEIERVQE----RLQALQ 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1480 RRH-----REQERKLQD---LELDLETRAKDVKARL-ALLEVQEETARREKQQLLDV-----QRQVALKSEEATATHQQL 1545
Cdd:pfam09321  128 ALYpevsvSEEETEGQEtvtPTVDLETALGRIEESYrECVRDQEDYWKEEESKEVEMsaefrEEGGKKKSEEFQEQLGSL 207

                          170       180       190
                   ....*....|....*....|....*....|....
gi 2462523724 1546 EEAQKEHThllqsnqqlrEILDELQARKLKLESQ 1579
Cdd:pfam09321  208 ERFLKEHS----------EELEVLEKHILKHESE 231

COG2433

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

1424-1574

1.78e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 43.31 E-value: 1.78e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1424 QQVMAKAREQYEAEERKQR-------AELLGHLTgelERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLE--- 1493
Cdd:COG2433    353 ERVEKKVPPDVDRDEVKARvirglsiEEALEELI---EKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEaev 429

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1494 LDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARK 1573
Cdd:COG2433    430 EELEAELEEKDERIERLERELSEARSEERREIRKDREISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGE 509


                   .
gi 2462523724 1574 L 1574
Cdd:COG2433    510 L 510

PRK11281

mechanosensitive channel MscK;

1254-1581

1.89e-03

mechanosensitive channel MscK;

Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 43.36 E-value: 1.89e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1254 RAEQEASLQKL--REELESQQKAERASLEQ---------KNRQMLEQLKEEIEASE---KSEQAALNAAKEKALQQLREQ 1319
Cdd:PRK11281    38 EADVQAQLDALnkQKLLEAEDKLVQQDLEQtlalldkidRQKEETEQLKQQLAQAPaklRQAQAELEALKDDNDEETRET 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1320 LEgerKEAVATLEK---EHSAELERLCSSLEAKHREVVSS------LQKKIQEAQQkeeaQLQkclgqvehrvhqksyhv 1390
Cdd:PRK11281   118 LS---TLSLRQLESrlaQTLDQLQNAQNDLAEYNSQLVSLqtqperAQAALYANSQ----RLQ----------------- 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1391 agyehELSSLLreKRQEVEGEHERRLDKMKEEHQQVMAKAREQYeaeerkQRAELLGH--LTgELERLQraheRELETVR 1468
Cdd:PRK11281   174 -----QIRNLL--KGGKVGGKALRPSQRVLLQAEQALLNAQNDL------QRKSLEGNtqLQ-DLLQKQ----RDYLTAR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1469 QEQhkrledlrrrhreQERKLQDL-ELDLETRAKDVKARLALLEVQEETARREKQQLldVQRQvalkSEEATATHQQLEE 1547
Cdd:PRK11281   236 IQR-------------LEHQLQLLqEAINSKRLTLSEKTVQEAQSQDEAARIQANPL--VAQE----LEINLQLSQRLLK 296

                          330       340       350
                   ....*....|....*....|....*....|....
gi 2462523724 1548 AQKEHTHLLQSNQQLREILDELQARKLKLESQVD 1581
Cdd:PRK11281   297 ATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQIS 330

OmpH

pfam03938

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

1262-1367

1.92e-03

Pssm-ID: 461098 [Multi-domain] Cd Length: 140 Bit Score: 40.64 E-value: 1.92e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1262 QKLREELESQQKAERASLEQKNRQmLEQLKEEIEAsEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKehsaeler 1341
Cdd:pfam03938   18 KAAQAQLEKKFKKRQAELEAKQKE-LQKLYEELQK-DGALLEEEREEKEQELQKKEQELQQLQQKAQQELQK-------- 87

                           90       100
                   ....*....|....*....|....*.
gi 2462523724 1342 lcssleaKHREVVSSLQKKIQEAQQK 1367
Cdd:pfam03938   88 -------KQQELLQPIQDKINKAIKE 106

ClpA

COG0542

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...

1277-1370

1.94e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 43.15 E-value: 1.94e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1277 ASLEQKNRQmLEQLKEEIEASEKsEQAALNAAKEKALQQLREQLEGERKEAVA--TLEKEHSAELERLCSSLEAKHrEVV 1354
Cdd:COG0542    411 EELDELERR-LEQLEIEKEALKK-EQDEASFERLAELRDELAELEEELEALKArwEAEKELIEEIQELKEELEQRY-GKI 487

                           90
                   ....*....|....*.
gi 2462523724 1355 SSLQKKIQEAQQKEEA 1370
Cdd:COG0542    488 PELEKELAELEEELAE 503

PRK11091

aerobic respiration control sensor protein ArcB; Provisional

1462-1535

2.09e-03

aerobic respiration control sensor protein ArcB; Provisional

Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 43.01 E-value: 2.09e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1462 RELETVRQEQHK---RLEDLRRRHREQERKLQD----LELDLETRAKDVKARLALL-EVQEETARREKQQLLDVQRQVAL 1533
Cdd:PRK11091    78 EQLEESRQRLSRlvaKLEEMRERDLELNVQLKDniaqLNQEIAEREKAEEARQEAFeQLKNEIKEREETQIELEQQSSLL 157


                   ..
gi 2462523724 1534 KS 1535
Cdd:PRK11091   158 RS 159

MAD

pfam05557

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...

1397-1570

2.17e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.

Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 43.19 E-value: 2.17e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1397 LSSLLREKRQEvEGEHERRLDKMKEEhqqvmAKAREQYEAEERKQRAELLGHLTGELERLQRAHE---RELETVRQEQhK 1473
Cdd:pfam05557   11 LSQLQNEKKQM-ELEHKRARIELEKK-----ASALKRQLDRESDRNQELQKRIRLLEKREAEAEEalrEQAELNRLKK-K 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1474 RLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHT 1553
Cdd:pfam05557   84 YLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQS 163

                          170
                   ....*....|....*..
gi 2462523724 1554 HLLQSNQQLREILDELQ 1570
Cdd:pfam05557  164 SLAEAEQRIKELEFEIQ 180

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1307-1482

2.26e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 2.26e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1307 AAKEKALQQLREQLeGERKEAVATLEKEHsAELERLCSSLEAKHREV---VSSLQKKIQEAQQKEEaQLQKCLGQVehrv 1383
Cdd:COG1579     13 QELDSELDRLEHRL-KELPAELAELEDEL-AALEARLEAAKTELEDLekeIKRLELEIEEVEARIK-KYEEQLGNV---- 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1384 hQKSYHVAGYEHELSSLlrEKRQEVEGEHERRLDKMKEEHQQVMAKAREQYE------AEERKQRAELLGHLTGELERLQ 1457
Cdd:COG1579     86 -RNNKEYEALQKEIESL--KRRISDLEDEILELMERIEELEEELAELEAELAeleaelEEKKAELDEELAELEAELEELE 162

                          170       180
                   ....*....|....*....|....*
gi 2462523724 1458 RAHERELETVRQEQHKRLEDLRRRH 1482
Cdd:COG1579    163 AEREELAAKIPPELLALYERIRKRK 187

PLC-beta_C

pfam08703

PLC-beta C terminal; This domain corresponds to the alpha helical C terminal domain of ...

1252-1411

2.30e-03

PLC-beta C terminal; This domain corresponds to the alpha helical C terminal domain of phospholipase C beta.

Pssm-ID: 462571 [Multi-domain] Cd Length: 176 Bit Score: 41.20 E-value: 2.30e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1252 QIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATL 1331
Cdd:pfam08703    2 QVRELKERLEQELLELREEQYEQEKKRKEQHLTEQIQKLKELAREKQAAELKALKESSESEKKEMKKKLERKRLESIQEA 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1332 EK--EHSAELERLCSSLEAKH-REVVSS---LQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV-AGYEHELSSLLREK 1404
Cdd:pfam08703   82 KKrtSDKAAQERLKKEINNSHiQEVVQSikqLEEKQKRRQEKLEEKQAECLQQIKEEEPQLQAELnAEYEEKLKGLPAEV 161


                   ....*..
gi 2462523724 1405 RQEVEGE 1411
Cdd:pfam08703  162 RESVKSC 168

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

1154-1502

2.31e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.58 E-value: 2.31e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1154 EAALKAMEEAVAQVleQDQRHLLESKQEKMQQLREKLCQEEEEEilrlhQQKEQSLSSLRERLQKAieeeearmreeeSQ 1233
Cdd:COG4372     34 RKALFELDKLQEEL--EQLREELEQAREELEQLEEELEQARSEL-----EQLEEELEELNEQLQAA------------QA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1234 RLSWLRAQVQSsTQADEDQIRAEQEAsLQKLREELESQQKAERASLEQKNRQM-------------LEQLKEEIEASEKS 1300
Cdd:COG4372     95 ELAQAQEELES-LQEEAEELQEELEE-LQKERQDLEQQRKQLEAQIAELQSEIaereeelkeleeqLESLQEELAALEQE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1301 EQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVE 1380
Cdd:COG4372    173 LQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELL 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1381 HRVHQKSYHVAGYEhelssLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAH 1460
Cdd:COG4372    253 EEVILKEIEELELA-----ILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKK 327

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 2462523724 1461 ERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKD 1502
Cdd:COG4372    328 LELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGVAD 369

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

1257-1651

2.58e-03

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.11 E-value: 2.58e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1257 QEASLQKLREELESQQKAERASLEQKNR------QMLEQLKEEIEASEKSEQAALNAAKEKALQ--------QLREQLEG 1322
Cdd:TIGR00606  502 EVKSLQNEKADLDRKLRKLDQEMEQLNHhtttrtQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpnkkQLEDWLHS 581

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1323 ERKEAVATleKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKC--------LGQVEHRVHQKSYH---VA 1391
Cdd:TIGR00606  582 KSKEINQT--RDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCgsqdeesdLERLKEEIEKSSKQramLA 659

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1392 GYEHELSSLLREKRQEVEGEHE--RRLDKMKEEHQQVMAKAREQYEAEERKQRAellghLTGELERLQRAHERELETVRQ 1469
Cdd:TIGR00606  660 GATAVYSQFITQLTDENQSCCPvcQRVFQTEAELQEFISDLQSKLRLAPDKLKS-----TESELKKKEKRRDEMLGLAPG 734

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1470 EQH------KRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEE------TARREKQQLLDVQRQVA----- 1532
Cdd:TIGR00606  735 RQSiidlkeKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVcltdvtIMERFQMELKDVERKIAqqaak 814

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1533 LKSEEATATHQQL----EEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLL 1608
Cdd:TIGR00606  815 LQGSDLDRTVQQVnqekQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELS 894

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 2462523724 1609 REVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQSK 1651
Cdd:TIGR00606  895 TEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNK 937

CCDC154

pfam15450

Coiled-coil domain-containing protein 154; CCDC154 is an osteopetrosis-related protein that ...

1243-1470

2.92e-03

Coiled-coil domain-containing protein 154; CCDC154 is an osteopetrosis-related protein that suppresses cell proliferation by inducing G2/M arrest.

Pssm-ID: 464723 [Multi-domain] Cd Length: 526 Bit Score: 42.51 E-value: 2.92e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1243 QSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKE------EIEASEKSEQAALN---AAKEKAl 1313
Cdd:pfam15450  213 ESTRLKAESSLREELEGRWQKLQELTEERLRALQGQREQEEGHLLEQCRGldaavvQLTKFVRQNQVSLNrvlLAEQKA- 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1314 QQLREQLEGERKEAVATLEKEhsaELERLCSSLEAKHREVVSSLQKKIQEAQQKEE--AQLQKCLGQVEHRVHQKSYHVA 1391
Cdd:pfam15450  292 RDAKGQLEESQAGELASYVQE---NLEAVQLAGELAQQETQGALELLQEKSQVLEGsvAELVRQVKDLSDHFLALSWRLD 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1392 GYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA------ELLGHLTGELERLQ---RAHER 1462
Cdd:pfam15450  369 LQEQTLGLKLSEAKKEWEGAERKSLEDLAQWQKEVAAHLREVQEKVDSLPRQieavsdKCVLHKSDSDLKISaegKAREF 448


                   ....*...
gi 2462523724 1463 ELETVRQE 1470
Cdd:pfam15450  449 EVEAMRQE 456

ATP-synt_Fo_b

cd06503

F-type ATP synthase, membrane subunit b; Membrane subunit b is a component of the Fo complex ...

1251-1319

2.98e-03

F-type ATP synthase, membrane subunit b; Membrane subunit b is a component of the Fo complex of FoF1-ATP synthase. The F-type ATP synthases (FoF1-ATPase) consist of two structural domains: the F1 (assembly factor one) complex containing the soluble catalytic core, and the Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F1 is composed of alpha (or A), beta (B), gamma (C), delta (D) and epsilon (E) subunits with a stoichiometry of 3:3:1:1:1, while Fo consists of the three subunits a, b, and c (1:2:10-14). An oligomeric ring of 10-14 c subunits (c-ring) make up the Fo rotor. The flux of protons through the ATPase channel (Fo) drives the rotation of the c-ring, which in turn is coupled to the rotation of the F1 complex gamma subunit rotor due to the permanent binding between the gamma and epsilon subunits of F1 and the c-ring of Fo. The F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. The F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis. This group also includes F-ATP synthase that has also been found in the archaea Candidatus Methanoperedens.

Pssm-ID: 349951 [Multi-domain] Cd Length: 132 Bit Score: 39.73 E-value: 2.98e-03

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1251 DQIRAEQEASLQKLREELESQ-QKAERASLEQKNrQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQ 1319
Cdd:cd06503     50 EELLAEYEEKLAEARAEAQEIiEEARKEAEKIKE-EILAEAKEEAERILEQAKAEIEQEKEKALAELRKE 118

hsdR

PRK11448

type I restriction enzyme EcoKI subunit R; Provisional

1398-1518

3.13e-03

type I restriction enzyme EcoKI subunit R; Provisional

Pssm-ID: 236912 [Multi-domain] Cd Length: 1123 Bit Score: 42.63 E-value: 3.13e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1398 SSLLREKRQEVEgeherRLDKMKEEHQQvmAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQE-QHKRLE 1476
Cdd:PRK11448   141 ENLLHALQQEVL-----TLKQQLELQAR--EKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKaAETSQE 213

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2462523724 1477 DLRRRHREQERKLQDLELD-LETRAK-DVKARLALLEVQEETAR 1518
Cdd:PRK11448   214 RKQKRKEITDQAAKRLELSeEETRILiDQQLRKAGWEADSKTLR 257

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

1436-1653

3.53e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.81 E-value: 3.53e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1436 AEERKQRAELLGHLTGELERLQRaherELETVRQEQHKRLEDLRRRHREQER---KLQDLELDLETRAKDVKARLALLEV 1512
Cdd:COG4372     30 SEQLRKALFELDKLQEELEQLRE----ELEQAREELEQLEEELEQARSELEQleeELEELNEQLQAAQAELAQAQEELES 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1513 QEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQK 1592
Cdd:COG4372    106 LQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQAL 185

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462523724 1593 HFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQSKED 1653
Cdd:COG4372    186 DELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEE 246

PspA_IM30

pfam04012

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ...

1453-1572

3.72e-03

Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 40.82 E-value: 3.72e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1453 LERLQRAHERELETVRQEqhkrLEDLRRRHREQERKLQDLELDLETRAKdvKARLALLEVQEETARREKQQLLDVQRQVA 1532
Cdd:pfam04012   27 LEQAIRDMQSELVKARQA----LAQTIARQKQLERRLEQQTEQAKKLEE--KAQAALTKGNEELAREALAEKKSLEKQAE 100

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 2462523724 1533 LKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQAR 1572
Cdd:pfam04012  101 ALETQLAQQRSAVEQLRKQLAALETKIQQLKAKKNLLKAR 140

PRK02292

V-type ATP synthase subunit E; Provisional

1242-1379

3.96e-03

V-type ATP synthase subunit E; Provisional

Pssm-ID: 235026 [Multi-domain] Cd Length: 188 Bit Score: 40.37 E-value: 3.96e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1242 VQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSE--QAALNAAKEkALQQLREQ 1319
Cdd:PRK02292    10 IRDEARARASEIRAEADEEAEEIIAEAEADAEEILEDREAEAEREIEQLREQELSSAKLEakRERLNARKE-VLEDVRNQ 88

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462523724 1320 LEgerkEAVATLEKEHSAELER-LCSSLEAKHREVVSS------LQKKIQEAQQKEEAQLQKCLGQV 1379
Cdd:PRK02292    89 VE----DEIASLDGDKREELTKsLLDAADADGVRVYSRkddedlVKSLLSDYDGLEYAGNIDCLGGV 151

4HB_MCP_1

pfam12729

Four helix bundle sensory module for signal transduction; This family is a four helix bundle ...

1249-1333

4.35e-03

Four helix bundle sensory module for signal transduction; This family is a four helix bundle that operates as a ubiquitous sensory module in prokaryotic signal-transduction. The 4HB_MCP is always found between two predicted transmembrane helices indicating that it detects only extracellular signals. In many cases the domain is associated with a cytoplasmic HAMP domain suggesting that most proteins carrying the bundle might share the mechanism of transmembrane signalling which is well-characterized in E coli chemoreceptors. This domain recognizes citrate and TCA cycle intermediates, cis-aconitate, boric acid, Phenanthrene, pyrene and benzopyrene (Matilla et el., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).

Pssm-ID: 432749 [Multi-domain] Cd Length: 181 Bit Score: 40.31 E-value: 4.35e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1249 DEDQiRAEQEASLQKLREELESQQKA-ERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAK----EKALQQLREQLEGE 1323
Cdd:pfam12729   73 DPAE-RDELLKDIEELRAEIDKLLEKyEKTILTDEEKKLFAEFKENLNAYRAVRNKVLELAKagnkDEAYQLYKTEGRPA 151

                           90
                   ....*....|
gi 2462523724 1324 RKEAVATLEK 1333
Cdd:pfam12729  152 REAMIEALEE 161

CusB_dom_1

pfam00529

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...

1247-1373

4.79e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.

Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 41.25 E-value: 4.79e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1247 QADEDQIRAEQeASLQKLREELesQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEkALQQLREQLEGERKE 1326
Cdd:pfam00529   57 QAALDSAEAQL-AKAQAQVARL--QAELDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQA-QLAQAQIDLARRRVL 132

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2462523724 1327 AVATL-EKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQ 1373
Cdd:pfam00529  133 APIGGiSRESLVTAGALVAQAQANLLATVAQLDQIYVQITQSAAENQA 180

PRK13895

conjugal transfer protein TraM; Provisional

1281-1351

4.87e-03

conjugal transfer protein TraM; Provisional

Pssm-ID: 184378 Cd Length: 144 Bit Score: 39.66 E-value: 4.87e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1281 QKNRQ-MLEQLKEEIE---------ASEKSEQ---AALNAAKEKALQQLREQLegerKEAVATLEKEHSAELERLCSSLE 1347
Cdd:PRK13895    41 AKAQQeMLDQFKEELEsiasrwgddAKEKAERilnAALAASKEAMAKGMQEGA----KAAAEAVRREISASLAELAAPVR 116


                   ....
gi 2462523724 1348 AKHR 1351
Cdd:PRK13895   117 EARR 120

OmpH

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

1236-1335

5.31e-03

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 39.10 E-value: 5.31e-03

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  1236 SWLRAQVQSSTQADEDQIRAE---QEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKA 1312
Cdd:smart00935   13 SPAGKAAQKQLEKEFKKRQAElekLEKELQKLKEKLQKDAATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQKRQQEE 92

                            90       100
                    ....*....|....*....|...
gi 2462523724  1313 LQQLREQLegerKEAVATLEKEH 1335
Cdd:smart00935   93 LQKILDKI----NKAIKEVAKKK 111

Mplasa_alph_rch

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

1263-1765

5.55e-03

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.93 E-value: 5.55e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1263 KLREELESQQKAERASLEQKNRQMLEQLKE-EIEASEKSEQAALNAAKEKALQQLREQLEGER----------KEAVATL 1331
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKLEKQKKENKKNIDKfLTEIKKKEKELEKLNNKYNDLKKQKEELENELnllekeklniQKNIDKI 192

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1332 EKEHSAeLERLCSSLEAKHREVvSSLQKKIQEAQQKEEaQLQKCLGQVEHRVHQKsyhvagyEHELSSLlREKRQEVEGE 1411
Cdd:TIGR04523  193 KNKLLK-LELLLSNLKKKIQKN-KSLESQISELKKQNN-QLKDNIEKKQQEINEK-------TTEISNT-QTQLNQLKDE 261

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1412 HERRLDKMKEEHQQVmakareqyeaeerKQRAELLGHLTGELERLqrahERELETVRQE-QHKRLEDLRRRHREQERKLQ 1490
Cdd:TIGR04523  262 QNKIKKQLSEKQKEL-------------EQNNKKIKELEKQLNQL----KSEISDLNNQkEQDWNKELKSELKNQEKKLE 324

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1491 DLELDLETrakdvkarlallevQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQ 1570
Cdd:TIGR04523  325 EIQNQISQ--------------NNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLE 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1571 ARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQK--KQHLLREVTVEENNASphfepdlhIEDLRKslgTNQTKEVS-SSL 1647
Cdd:TIGR04523  391 SQINDLESKIQNQEKLNQQKDEQIKKLQQEKELleKEIERLKETIIKNNSE--------IKDLTN---QDSVKELIiKNL 459

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1648 SQSKEDL--YLDSLSshnvwhllsaegvalrsakeflvqqtRSMRRRQTALKAAQqhwrhelasaQEVAKDPPGIKALED 1725
Cdd:TIGR04523  460 DNTRESLetQLKVLS--------------------------RSINKIKQNLEQKQ----------KELKSKEKELKKLNE 503

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 2462523724 1726 MRKNLEKETRHL----DEMKSAMRKGHNLLKKKEEKLNQLESSL 1765
Cdd:TIGR04523  504 EKKELEEKVKDLtkkiSSLKEKIEKLESEKKEKESKISDLEDEL 547

PRK12705

hypothetical protein; Provisional

1414-1557

5.65e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 41.62 E-value: 5.65e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1414 RRLDKMKEEHQQVMAKAREqyeaEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQER---KLQ 1490
Cdd:PRK12705    26 KKRQRLAKEAERILQEAQK----EAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDAraeKLD 101

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462523724 1491 DLELDLETRAKDVKARLALLEVQEETARREKQQLL----DVQRQVALKSEEATATHQ--QLEEAQKEHTHLLQ 1557
Cdd:PRK12705   102 NLENQLEEREKALSARELELEELEKQLDNELYRVAgltpEQARKLLLKLLDAELEEEkaQRVKKIEEEADLEA 174

MPS2

pfam17060

Monopolar spindle protein 2; Is a fungal transmembrane protein which is part of the component ...

1238-1384

5.80e-03

Monopolar spindle protein 2; Is a fungal transmembrane protein which is part of the component of the spindle pole body (SPB) required for the insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication. It seems that Mps2-Spc24 interaction may contribute to the localization of Spc24 and other kinetochore components to the inner plaque of the SPB.

Pssm-ID: 407228 [Multi-domain] Cd Length: 340 Bit Score: 41.11 E-value: 5.80e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1238 LRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM-LEQLKEEIEASEKseqaaLNAAKEKALQQL 1316
Cdd:pfam17060  106 LKEDVKSSPRSEADSLGTPIKVDLLRNLKPQESPETPRRINRKYKSLELrVESMKDELEFKDE-----TIMEKDRELTEL 180

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462523724 1317 REQLeGERKEAVATLEKEHS-----AELERLCSSLEA-KHREVVSSLQKKIQEaQQKEEAQLQKCLGQVEHRVH 1384
Cdd:pfam17060  181 TSTI-SKLKDKYDFLSREFEfykqhHEHGGNNSIKTAtKHEFIISELKRKLQE-QNRLIRILQEQIQFDPGALH 252

ARGLU

pfam15346

Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is ...

1394-1525

5.84e-03

Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is required for the oestrogen-dependent expression of ESR1 target genes. It functions in cooperation with MED1. The family of proteins is found in eukaryotes.

Pssm-ID: 405931 [Multi-domain] Cd Length: 151 Bit Score: 39.26 E-value: 5.84e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1394 EHELSSLLREKRQEVEGEHERRLDKMKEE-HQQVMAKAREQYEAEERKQRAEllghltgelERLQRAHERELETVRQEQH 1472
Cdd:pfam15346   21 AKRVEEELEKRKDEIEAEVERRVEEARKImEKQVLEELEREREAELEEERRK---------EEEERKKREELERILEENN 91

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462523724 1473 KRLEDLRRRHREQERKlqdlELDLETRAKDVKARLAllEVQEETARREKQQLL 1525
Cdd:pfam15346   92 RKIEEAQRKEAEERLA----MLEEQRRMKEERQRRE--KEEEEREKREQQKIL 138

Apolipoprotein

pfam01442

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...

1313-1507

5.88e-03

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.

Pssm-ID: 460211 [Multi-domain] Cd Length: 175 Bit Score: 39.94 E-value: 5.88e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1313 LQQLREQLEGERKEAVATLEKEhsaeLERLCSSLEAKHREVVSSLQKKIQEAQQKeeaqlqkcLGQvehrvhqksyHVAG 1392
Cdd:pfam01442   13 AEELQEQLGPVAQELVDRLEKE----TEALRERLQKDLEEVRAKLEPYLEELQAK--------LGQ----------NVEE 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1393 YEHELSSLLREKRQEVEgeheRRLDKMKEEHQQVMAKAREQYEAEERKQRAellgHLTGELERLQRAHERELETVRQEQH 1472
Cdd:pfam01442   71 LRQRLEPYTEELRKRLN----ADAEELQEKLAPYGEELRERLEQNVDALRA----RLAPYAEELRQKLAERLEELKESLA 142

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2462523724 1473 KRLEDLRRRHREQerkLQDLELDLETRAKDVKARL 1507
Cdd:pfam01442  143 PYAEEVQAQLSQR---LQELREKLEPQAEDLREKL 174

PRK07352

F0F1 ATP synthase subunit B; Validated

1238-1321

6.32e-03

F0F1 ATP synthase subunit B; Validated

Pssm-ID: 180941 [Multi-domain] Cd Length: 174 Bit Score: 39.55 E-value: 6.32e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1238 LRAQVQSSTQADEDQIRAEQEAslQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQA---------ALNAA 1308
Cdd:PRK07352    66 LRQAAQALAEAQQKLAQAQQEA--ERIRADAKARAEAIRAEIEKQAIEDMARLKQTAAADLSAEQErviaqlrreAAELA 143

                           90
                   ....*....|...
gi 2462523724 1309 KEKALQQLREQLE 1321
Cdd:PRK07352   144 IAKAESQLPGRLD 156

PRK11637

AmiB activator; Provisional

1424-1610

6.33e-03

AmiB activator; Provisional

Pssm-ID: 236942 [Multi-domain] Cd Length: 428 Bit Score: 41.22 E-value: 6.33e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1424 QQVMAkAREQYEAEERKQRAELLGHLTGELE------RLQRAHERELETVRQEQHK---RLEDLRRRHREQERKLQDlEL 1494
Cdd:PRK11637    53 QQDIA-AKEKSVRQQQQQRASLLAQLKKQEEaisqasRKLRETQNTLNQLNKQIDElnaSIAKLEQQQAAQERLLAA-QL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1495 DLETRAKDVKArLALLEVQEETARREKQQ----LLDVQRQVALksEEATATHQQLEEAQKEhthLLQSNQQLREILDELQ 1570
Cdd:PRK11637   131 DAAFRQGEHTG-LQLILSGEESQRGERILayfgYLNQARQETI--AELKQTREELAAQKAE---LEEKQSQQKTLLYEQQ 204

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2462523724 1571 ARKLKLESqvdllqaQSQQLQKHFSSLEAEAQKKQHLLRE 1610
Cdd:PRK11637   205 AQQQKLEQ-------ARNERKKTLTGLESSLQKDQQQLSE 237

PKK

pfam12474

Polo kinase kinase; This domain family is found in eukaryotes, and is approximately 140 amino ...

1423-1556

6.35e-03

Polo kinase kinase; This domain family is found in eukaryotes, and is approximately 140 amino acids in length. The family is found in association with pfam00069. Polo-like kinase 1 (Plx1) is essential during mitosis for the activation of Cdc25C, for spindle assembly, and for cyclin B degradation. This family is Polo kinase kinase (PKK) which phosphorylates Polo kinase and Polo-like kinase to activate them. PKK is a serine/threonine kinase.

Pssm-ID: 463600 [Multi-domain] Cd Length: 139 Bit Score: 39.08 E-value: 6.35e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1423 HQQVMAKAREQYEAEerkqRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHR-EQERKLQDLELDLETRAK 1501
Cdd:pfam12474    1 HQLQKEQQKDRFEQE----RQQLKKRYEKELEQLERQQKQQIEKLEQRQTQELRRLPKRIRaEQKKRLKMFRESLKQEKK 76

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462523724 1502 DVKA---RLALLEVQEET-ARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLL 1556
Cdd:pfam12474   77 ELKQeveKLPKFQRKEAKrQRKEELELEQKHEELEFLQAQSEALERELQQLQNEKRKEL 135

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

1144-1426

6.37e-03

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.57 E-value: 6.37e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1144 EPVAPPEQLSEAALKAMeeavaQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLR------ERLQ 1217
Cdd:TIGR00606  775 GTIMPEEESAKVCLTDV-----TIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDtvvskiELNR 849

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1218 KAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREEL--ESQQKAERASLEQKNRQMLEQLKEEI- 1294
Cdd:TIGR00606  850 KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLirEIKDAKEQDSPLETFLEKDQQEKEELi 929

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1295 ---EASEKSEQAALNAAKEKALQQL--REQLEGERKEAVATLEKEHSAELERLCSSLEAKHREvvsslQKKIQEAQQKEE 1369
Cdd:TIGR00606  930 sskETSNKKAQDKVNDIKEKVKNIHgyMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKH-----QEKINEDMRLMR 1004

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462523724 1370 AQLQKclGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQV 1426
Cdd:TIGR00606 1005 QDIDT--QKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKL 1059

ClyA_Cry6Aa-like

cd22656

Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ...

1249-1333

6.42e-03

Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.

Pssm-ID: 439154 [Multi-domain] Cd Length: 309 Bit Score: 40.82 E-value: 6.42e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1249 DEDQIRAEQEasLQKLREELESQQKAERASLEQKnrqmLEQLKEEIEASEKSEQAA------LNAAKeKALQQLREQLEg 1322
Cdd:cd22656    171 DEGGAIARKE--IKDLQKELEKLNEEYAAKLKAK----IDELKALIADDEAKLAAAlrliadLTAAD-TDLDNLLALIG- 242

                           90
                   ....*....|.
gi 2462523724 1323 erkEAVATLEK 1333
Cdd:cd22656    243 ---PAIPALEK 250

growth_prot_Scy

NF041483

polarized growth protein Scy;

1232-1556

6.47e-03

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 41.74 E-value: 6.47e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1232 SQRLSWLRAQVQSSTQAdedQIRAEQEASLQKLREEL-ESQQKAE-------------RASLEQKNRQMLEQLKEEIEAS 1297
Cdd:NF041483   103 TQRILQEHAEHQARLQA---ELHTEAVQRRQQLDQELaERRQTVEshvnenvawaeqlRARTESQARRLLDESRAEAEQA 179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1298 EKSEQAALNAAKEKALQQLREQLEGERKEAVATLEK-----------------EHSAELERLCSSL-----EAKHR--EV 1353
Cdd:NF041483   180 LAAARAEAERLAEEARQRLGSEAESARAEAEAILRRarkdaerllnaastqaqEATDHAEQLRSSTaaesdQARRQaaEL 259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1354 VSSLQKKIQEAQQK---EEAQLQKCLGQVEHRVHQKsyhVAGYEHELSSLLREKRQEVE---GEHERRLDKMKEEHQQVM 1427
Cdd:NF041483   260 SRAAEQRMQEAEEAlreARAEAEKVVAEAKEAAAKQ---LASAESANEQRTRTAKEEIArlvGEATKEAEALKAEAEQAL 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1428 AKAREQYE-----AEERKQRA-----------------ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQ 1485
Cdd:NF041483   337 ADARAEAEklvaeAAEKARTVaaedtaaqlakaartaeEVLTKASEDAKATTRAAAEEAERIRREAEAEADRLRGEAADQ 416

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462523724 1486 ERKLQDLELD--LETRAKDVkarlallEVQEEtARR---EKQQLLD--VQRQVALKSEEATATHQQLEEAQKEHTHLL 1556
Cdd:NF041483   417 AEQLKGAAKDdtKEYRAKTV-------ELQEE-ARRlrgEAEQLRAeaVAEGERIRGEARREAVQQIEEAARTAEELL 486

Treacle

pfam03546

Treacher Collins syndrome protein Treacle;

823-1181

6.58e-03

Treacher Collins syndrome protein Treacle;

Pssm-ID: 460967 [Multi-domain] Cd Length: 531 Bit Score: 41.21 E-value: 6.58e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  823 SQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKGRQGSGARPGLPEK--------------EENEKSEPKICRN 888
Cdd:pfam03546   26 SSSEEESDSEEETPAAKTPLQAKPSGKTPQVRAASAPAKESPRKGAPPVPPGKtgpaaaqaqagkpeEDSESSSEESDSD 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  889 LVTPKADPTGSEPAKA--SEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQElEISEHMKEPQLSDSIASD 966
Cdd:pfam03546  106 GETPAAATLTTSPAQVkpLGKNSQVRPASTVGKGPSGKGANPAPPGKAGSAAPLVQVGKKE-EDSESSSEESDSEGEAPP 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724  967 PKSfhgldfgfRSRISEHLLDVDVLSPVLGGACRQAQQPLGI--------EDKDDSQSSQDELQSKQSKGLEERYHRLSP 1038
Cdd:pfam03546  185 AAT--------QAKPSGKILQVRPASGPAKGAAPAPPQKAGPvatqvkaeRSKEDSESSEESSDSEEEAPAAATPAQAKP 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1039 PLPHEERAQSP----PRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEEL 1114
Cdd:pfam03546  257 ALKTPQTKASPrkgtPITPTSAKVPPVRVGTPAPWKAGTVTSPACASSPAVARGAQRPEEDSSSSEESESEEETAPAAAV 336

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462523724 1115 GPGQEEAEDPEEKVAVSPTPpvSPEVRSTEPVAPpeqlseaalKAMEEAVAQVLEQDQRHLLESKQE 1181
Cdd:pfam03546  337 GQAKSVGKGLQGKAASAPTK--GPSGQGTAPVPP---------GKTGPAVAQVKAEAQEDSESSEEE 392

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

1266-1446

7.30e-03

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 41.35 E-value: 7.30e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1266 EELESQQKaeraSLEQKNRQmLEQLKEEIEAsekseqaalnaaKEKALQQLREQLEGERKEAVATLEKEhsaelerlcss 1345
Cdd:PRK00409   523 ASLEELER----ELEQKAEE-AEALLKEAEK------------LKEELEEKKEKLQEEEDKLLEEAEKE----------- 574

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1346 leakhrevvssLQKKIQEAqQKEEAQLQKCLgqvehRVHQKSYHVAGYEHELSsllrEKRQEVEGEHErrldkMKEEHQQ 1425
Cdd:PRK00409   575 -----------AQQAIKEA-KKEADEIIKEL-----RQLQKGGYASVKAHELI----EARKRLNKANE-----KKEKKKK 628

                          170       180
                   ....*....|....*....|....*..
gi 2462523724 1426 VMAKAREQYEAEER------KQRAELL 1446
Cdd:PRK00409   629 KQKEKQEELKVGDEvkylslGQKGEVL 655

CCDC154

pfam15450

Coiled-coil domain-containing protein 154; CCDC154 is an osteopetrosis-related protein that ...

1257-1540

7.53e-03

Coiled-coil domain-containing protein 154; CCDC154 is an osteopetrosis-related protein that suppresses cell proliferation by inducing G2/M arrest.

Pssm-ID: 464723 [Multi-domain] Cd Length: 526 Bit Score: 41.36 E-value: 7.53e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1257 QEASLQKLREELE-----SQQKAERASLEQKNRQMLEQL-KEEIEASEKSEQAALNAAkEKALQQLREQL-EGERKEAVA 1329
Cdd:pfam15450   40 EHATLSLLRELLQvrahvQLQDSELKQLRQEVQQAARAPeKEALEFPGPQNQNQMQAL-DKRLVEVREALtQIRRKQALQ 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1330 TLEKEHSAE-----LERLCSSL--EAKHREVV-SSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLL 1401
Cdd:pfam15450  119 DSERKGAEQeanlrLTKLTGKLkqEEQGREAAcSALQKSQEEASQKVDHEVARMQAQVTKLGEEMSLRFLKREAKLCSFL 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1402 R------EKRQEVEG----EHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQ 1471
Cdd:pfam15450  199 QksflalEKRMKASEstrlKAESSLREELEGRWQKLQELTEERLRALQGQREQEEGHLLEQCRGLDAAVVQLTKFVRQNQ 278

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462523724 1472 HKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATA 1540
Cdd:pfam15450  279 VSLNRVLLAEQKARDAKGQLEESQAGELASYVQENLEAVQLAGELAQQETQGALELLQEKSQVLEGSVA 347

PspA

COG1842

Phage shock protein A [Transcription, Signal transduction mechanisms];

1461-1579

7.77e-03

Phage shock protein A [Transcription, Signal transduction mechanisms];

Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 39.81 E-value: 7.77e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1461 ERELETVRQE------QHKRLEDLRRRHREQERKLQDleldletrakdvKARLALLEVQEETARR--EKQQLLDvqrqva 1532
Cdd:COG1842     36 EEDLVEARQAlaqviaNQKRLERQLEELEAEAEKWEE------------KARLALEKGREDLAREalERKAELE------ 97

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 2462523724 1533 lksEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQ 1579
Cdd:COG1842     98 ---AQAEALEAQLAQLEEQVEKLKEALRQLESKLEELKAKKDTLKAR 141

WEMBL

pfam05701

Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required ...

1243-1444

8.11e-03

Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required for the chloroplast avoidance response under high intensity blue light. This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells. Acts in association with PMI2 to maintain the velocity of chloroplast photo-relocation movement via the regulation of cp-actin filaments. Thus several member-sequences are described as "myosin heavy chain-like".

Pssm-ID: 461718 [Multi-domain] Cd Length: 562 Bit Score: 41.17 E-value: 8.11e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1243 QSSTQADEDQIRAEQ-EASLQKLREELEsQQKAERASLEQKnrqmLEQLKEEIEASEKSEQAALNAAkeKALQQLREQLE 1321
Cdd:pfam05701  388 QAAQEAEEAKSLAQAaREELRKAKEEAE-QAKAAASTVESR----LEAVLKEIEAAKASEKLALAAI--KALQESESSAE 460

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1322 GERKEAVA---TLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQqkeeaqlqkclgqvehrvhqksyhvagyEHELS 1398
Cdd:pfam05701  461 STNQEDSPrgvTLSLEEYYELSKRAHEAEELANKRVAEAVSQIEEAK----------------------------ESELR 512

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462523724 1399 SLlrEKRQEVEGEHERRLDKMKEEHQQVmAKARE---QYEAEERKQRAE 1444
Cdd:pfam05701  513 SL--EKLEEVNREMEERKEALKIALEKA-EKAKEgklAAEQELRKWRAE 558

PTZ00491

major vault protein; Provisional

1279-1474

8.13e-03

major vault protein; Provisional

Pssm-ID: 240439 [Multi-domain] Cd Length: 850 Bit Score: 41.16 E-value: 8.13e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1279 LEQKNRQMLEQ-LKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELErlcssLEAKHREVVSSL 1357
Cdd:PTZ00491   641 VDERTRDSLQKsVQLAIEITTKSQEAAARHQAELLEQEARGRLERQKMHDKAKAEEQRTKLLE-----LQAESAAVESSG 715

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1358 QKKiQEAQQKEEAQLQKClgqvehrvhQKSYHVAGyehelsslLREKRQEVEGEHErrLDKMKEEHQQvmakareqyEAE 1437
Cdd:PTZ00491   716 QSR-AEALAEAEARLIEA---------EAEVEQAE--------LRAKALRIEAEAE--LEKLRKRQEL---------ELE 766

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2462523724 1438 ERKQRAELlghltgELERlqrahERELETVRQEQHKR 1474
Cdd:PTZ00491   767 YEQAQNEL------EIAK-----AKELADIEATKFER 792

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

1170-1580

8.41e-03

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.19 E-value: 8.41e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1170 QDQRHLLESKQEKMQQLREKLC--QEEEEEILRLHQQKEQSLSSLRERLQ----------------KAIEEEEARMREEE 1231
Cdd:TIGR00606  206 QMELKYLKQYKEKACEIRDQITskEAQLESSREIVKSYENELDPLKNRLKeiehnlskimkldneiKALKSRKKQMEKDN 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1232 SQrLSWLRAQVQSSTQADEDQI-RAEQEASLQKLREELESQQKAERASleqKNRQMLEQLKEEIEASEKSEQAALNAAKE 1310
Cdd:TIGR00606  286 SE-LELKMEKVFQGTDEQLNDLyHNHQRTVREKERELVDCQRELEKLN---KERRLLNQEKTELLVEQGRLQLQADRHQE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1311 KALQ--------QLREQLEGERKEAVATLEKEHSAELERLCSSLEAKH-REVVSSLQKKIQEAqQKEEAQLQKCLGQVEH 1381
Cdd:TIGR00606  362 HIRArdsliqslATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTaAQLCADLQSKERLK-QEQADEIRDEKKGLGR 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1382 RVHQKSYHVAGYEHELSSLLREKrQEVEGEHERRLDKMKE--EHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRA 1459
Cdd:TIGR00606  441 TIELKKEILEKKQEELKFVIKEL-QQLEGSSDRILELDQElrKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRK 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1460 HERELETVRQEQHKrledlrrrhREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQvalKSEEAT 1539
Cdd:TIGR00606  520 LDQEMEQLNHHTTT---------RTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHS---KSKEIN 587

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 2462523724 1540 ATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQV 1580
Cdd:TIGR00606  588 QTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKL 628

PTZ00491

major vault protein; Provisional

1245-1378

8.56e-03

major vault protein; Provisional

Pssm-ID: 240439 [Multi-domain] Cd Length: 850 Bit Score: 41.16 E-value: 8.56e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1245 STQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKE--EIEASEKSEQAALNAAK------EKALQQL 1316
Cdd:PTZ00491   660 TTKSQEAAARHQAELLEQEARGRLERQKMHDKAKAEEQRTKLLELQAEsaAVESSGQSRAEALAEAEarlieaEAEVEQA 739

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462523724 1317 REQLEGERKEAVATLEKEHsAELErlcssLEAKHREVVSSL----QKKIQEAQQKEEAQLQKCLGQ 1378
Cdd:PTZ00491   740 ELRAKALRIEAEAELEKLR-KRQE-----LELEYEQAQNELeiakAKELADIEATKFERIVEALGR 799

PRK12705

hypothetical protein; Provisional

1426-1580

8.89e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 40.85 E-value: 8.89e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1426 VMAKAREQY--EAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEdlRRRHREQERKLQDLELDLETRAKDV 1503
Cdd:PRK12705    23 VLLKKRQRLakEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARRE--REELQREEERLVQKEEQLDARAEKL 100

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462523724 1504 KARLALLEVQEETARREKQQLLDVQRQVALKSEEATAthqqleeaqkehthlLQSNQQLREILDELQArKLKLESQV 1580
Cdd:PRK12705   101 DNLENQLEEREKALSARELELEELEKQLDNELYRVAG---------------LTPEQARKLLLKLLDA-ELEEEKAQ 161

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

1247-1363

9.12e-03

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 40.25 E-value: 9.12e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1247 QADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEeieasekseqaalnaAKEKALQQLREQLEGERKE 1326
Cdd:cd16269    188 QADQALTEKEKEIEAERAKAEAAEQERKLLEEQQRELEQKLEDQER---------------SYEEHLRQLKEKMEEEREN 252

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2462523724 1327 AVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQE 1363
Cdd:cd16269    253 LLKEQERALESKLKEQEALLEEGFKEQAELLQEEIRS 289

Sfi1

pfam08457

Sfi1 spindle body protein; This is a family of fungal spindle pole body proteins that play a ...

1235-1571

9.37e-03

Sfi1 spindle body protein; This is a family of fungal spindle pole body proteins that play a role in spindle body duplication. They contain binding sites for calmodulin-like proteins called centrins which are present in microtubule-organizing centres.

Pssm-ID: 430007 [Multi-domain] Cd Length: 570 Bit Score: 40.74 E-value: 9.37e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1235 LSWLRA---QVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEaseksEQAALNAA--- 1308
Cdd:pfam08457  141 LTWLRKfrtLREREQEAEAKRKRLLLSSALQIWSERTEAVQAAEQEADSFRRRKLLRRALDEWR-----IQARLEPAlrq 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1309 ---------KEKALQQLREQLEGERKEA-VATLEKEHSA----ELERLCSSLEAK--HREVVSSLQK-----------KI 1361
Cdd:pfam08457  216 vsakvdrriLRSALSVWKLRARMSRQAReVDRARILRNAwttwNDELRCKALRERidERLKLEALYKwvleerlrlfqRI 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1362 QEAQQKEEA------QLQKCLGQV-----EHRVHQKSYHVAGYEHELSSLLREKRQE---VEGEHERR-----LDKMKEE 1422
Cdd:pfam08457  296 REQRLKREVlstwvtNTRDTRTRLlrheeEFEEHRNRKLLRSKLLKWRDQLAEQREReiaANEFYAPRllqeaLDAWRER 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1423 HQQVmakarEQYEAEERKQRAELLghLTGELER-----LQRAHERELETVRQEQHKRLEDLRRRH----REQERKLQDLE 1493
Cdd:pfam08457  376 HQHV-----QKLEKWARDARFYFL--ATRTLKKwraatEESRRERRQDAYAQVRRKVKINLARRAlskwRSKAAEVADLE 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1494 ldletrakdvkarlallevQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQ--QLREILDELQA 1571
Cdd:pfam08457  449 -------------------QQADQLRQNRLLEDAIELFDRWRERTAKRKQRAEDADQFYAEQLLRSYlaRWRERLRELRE 509

EVC2_like

pfam12297

Ellis van Creveld protein 2 like protein; This family of proteins is found in eukaryotes. ...

1394-1607

9.45e-03

Ellis van Creveld protein 2 like protein; This family of proteins is found in eukaryotes. Proteins in this family are typically between 571 and 1310 amino acids in length. There are two conserved sequence motifs: LPA and ELH. EVC2 is implicated in Ellis van Creveld chondrodysplastic dwarfism in humans. Mutations in this protein can give rise to this congenital condition. LIMBIN is a protein which shares around 80% sequence homology with EVC2 and it is implicated in a similar condition in bovine chondrodysplastic dwarfism.

Pssm-ID: 463525 [Multi-domain] Cd Length: 428 Bit Score: 40.84 E-value: 9.45e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1394 EHELSSLLREKRQEVEGE-HERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLghltgELERL-QRAHER---ELETVR 1468
Cdd:pfam12297  193 EKRMSSVFNKQFLAMEGRlQEEYERKMAALAAECNLETREKMEAQHQREMAEKE-----EAEELlKHADEQealECSSLL 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1469 QEQHK-RLEDLRR----RHREQERKLQdleldletRAKDVKARLALLEVQEEtarrekqQLLDVQRQVALKSEEATATHQ 1543
Cdd:pfam12297  268 DKLHKlEQEHLQRslllRQEEDFAKAQ--------RQLAVFQRVELHKIFFT-------QLKEATRKGELKPEAAKRLLQ 332

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462523724 1544 QLEEAQkehthllqsnQQLREILDELQARKLKLESqvdllqaqsqqlqKHFSSLEAEAQKKQHL 1607
Cdd:pfam12297  333 DYSKIQ----------EQIEELMDFFQANQRYHLS-------------ERFAQREYLVQSLQSL 373

mukB

chromosome partition protein MukB;

1459-1771

9.45e-03

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.10 E-value: 9.45e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1459 AHERELETVRQEQHK---RLEDLRRRHREQERKLQDLELDLEtrakDVKARLALleVQEETARREKQQlldvQRQVALks 1535
Cdd:PRK04863   290 ELRRELYTSRRQLAAeqyRLVEMARELAELNEAESDLEQDYQ----AASDHLNL--VQTALRQQEKIE----RYQADL-- 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1536 EEATAthqQLEEAQkehthllQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEA---QKKQHLLREVt 1612
Cdd:PRK04863   358 EELEE---RLEEQN-------EVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAiqyQQAVQALERA- 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1613 vEENNASPHFEPDlHIEDLRKSLgTNQTKEVSSSLSQSKEDLylDSLSSHNVWHLLSAEGV-----------ALRSAKEF 1681
Cdd:PRK04863   427 -KQLCGLPDLTAD-NAEDWLEEF-QAKEQEATEELLSLEQKL--SVAQAAHSQFEQAYQLVrkiagevsrseAWDVAREL 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1682 L---------VQQTRSMRRRQTALK---AAQQHWRHELASAQEVA-KDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGH 1748
Cdd:PRK04863   502 LrrlreqrhlAEQLQQLRMRLSELEqrlRQQQRAERLLAEFCKRLgKNLDDEDELEQLQEELEARLESLSESVSEARERR 581

                          330       340
                   ....*....|....*....|....*....
gi 2462523724 1749 NLLKKKEEKLNQLESSL------WEEASD 1771
Cdd:PRK04863   582 MALRQQLEQLQARIQRLaarapaWLAAQD 610

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

1166-1610

9.55e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.09 E-value: 9.55e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1166 QVLEQ--DQRHLLESKQEKMQQLREkLCQeeeeeilRLHQQkeQSLSSLRERLQKAIEEEEARMREEESQrLSWLRAQVQ 1243
Cdd:COG3096    499 ELLRRyrSQQALAQRLQQLRAQLAE-LEQ-------RLRQQ--QNAERLLEEFCQRIGQQLDAAEELEEL-LAELEAQLE 567

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1244 SSTQADEDQIraEQEASLQKLREELESQQK--AERASLEQKNRQMLEQLKEEIEASEKSEQAALNA-----AKEKALQQL 1316
Cdd:COG3096    568 ELEEQAAEAV--EQRSELRQQLEQLRARIKelAARAPAWLAAQDALERLREQSGEALADSQEVTAAmqqllEREREATVE 645

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1317 REQLEgERKEAvatLEKE----------HSAELERLCSSL-------------------------EAKHREVVSSLqkki 1361
Cdd:COG3096    646 RDELA-ARKQA---LESQierlsqpggaEDPRLLALAERLggvllseiyddvtledapyfsalygPARHAIVVPDL---- 717

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1362 qEAQQKEEAQLQKCLGQV--------------------EHRVHQKS---------------YHVAGYEHELSSLLREKRQ 1406
Cdd:COG3096    718 -SAVKEQLAGLEDCPEDLyliegdpdsfddsvfdaeelEDAVVVKLsdrqwrysrfpevplFGRAAREKRLEELRAERDE 796

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1407 EVEGEHERRLDKMKEE--HQQV-------MAKA-REQYEAEERKQRAELlghltGELERLQRAHERELetvrQEQHKRLE 1476
Cdd:COG3096    797 LAEQYAKASFDVQKLQrlHQAFsqfvgghLAVAfAPDPEAELAALRQRR-----SELERELAQHRAQE----QQLRQQLD 867

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1477 DLRRRhREQERKLQDL-----ELDLETRAKDVKARL-ALLEVQEETAR-----REKQQLLDVQRQVALKSEEATATHQQL 1545
Cdd:COG3096    868 QLKEQ-LQLLNKLLPQanllaDETLADRLEELREELdAAQEAQAFIQQhgkalAQLEPLVAVLQSDPEQFEQLQADYLQA 946

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462523724 1546 EEAQKE--------------HTHLLQS------------NQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEA 1599
Cdd:COG3096    947 KEQQRRlkqqifalsevvqrRPHFSYEdavgllgensdlNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKS 1026

                          570
                   ....*....|.
gi 2462523724 1600 EAQKKQHLLRE 1610
Cdd:COG3096   1027 SRDAKQQTLQE 1037

Myosin_tail_1