|
Name |
Accession |
Description |
Interval |
E-value |
| COMPASS-Shg1 |
pfam05205 |
COMPASS (Complex proteins associated with Set1p) component shg1; The Shg1 subunit is one of ... |
57-150 |
2.94e-28 |
|
COMPASS (Complex proteins associated with Set1p) component shg1; The Shg1 subunit is one of the eight subunits of the COMPASS complex, complex associated with SET1, conserved in yeasts and in other eukaryotes up to humans. It is associated with the region of the Set1 protein that is N-terminal to the C-terminus, ie Set1-560-900. The function of Shg1 seems to be to slightly inhibit histone 3 lysine 4 (H3K4) di- and tri-methylation, and it is a pioneer protein. The COMPASS complex functions to methylate the fourth lysine of Histone 3 and for silencing of genes close to the telomeres of chromosomes.
Pssm-ID: 461586 [Multi-domain] Cd Length: 100 Bit Score: 110.75 E-value: 2.94e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 57 IVNHLKSQGLFDQFRRDCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGML---ESGIDR 133
Cdd:pfam05205 2 LVHEFKKKGGFDKLRKDILADFDTSDAYQNLLQRLEEIVESEVERDPSLLSKNRGKAAALIEGAIDRSDVYkkaEAGVDR 81
|
90
....*....|....*....
gi 2462596362 134 IISQVV--DPKINHTFRPQ 150
Cdd:pfam05205 82 LIDQVLdiEPKIREIRRPE 100
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
213-1059 |
3.81e-17 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 89.43 E-value: 3.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 213 QEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKE-------RTSEDMADKEKSTADSGGEGLETAPKSEEFSDlpc 285
Cdd:PTZ00121 1161 EDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDarkaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKK--- 1237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 286 PVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEktekkfDHSKKSEDTQKVKDEKQAK 365
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA------DEAKKAEEKKKADEAKKKA 1311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 366 E--KEVESLKLPSEKNSNKAKTVEGTKEDFSLIDsdvdgltditvssvhtsdlssfEEDTEEEVVTSDSMEEGEITSDDE 443
Cdd:PTZ00121 1312 EeaKKADEAKKKAEEAKKKADAAKKKAEEAKKAA----------------------EAAKAEAEAAADEAEAAEEKAEAA 1369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 444 EKNKQNKTKtqTSDSSEGKTKSVRHAYvhkpylYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKA 523
Cdd:PTZ00121 1370 EKKKEEAKK--KADAAKKKAEEKKKAD------EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE 1441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 524 EKTKSSKTKGQGRSSVDLEESSTKSLEP-KAARIKEVLKERKVLE--KKVALSKKRKKDSRNVEENSKKKQQYEEDSKET 600
Cdd:PTZ00121 1442 EAKKADEAKKKAEEAKKAEEAKKKAEEAkKADEAKKKAEEAKKADeaKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEA 1521
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 601 LKTSEHCEKEKISSSKELKhvhaKSEPSKPARRLSESLHVvdeNKNESKIEREHKRRTSTPVIMEGVQEETDTRDVKRQV 680
Cdd:PTZ00121 1522 KKADEAKKAEEAKKADEAK----KAEEKKKADELKKAEEL---KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI 1594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 681 ERSEICTEEPQKQKStlkneKHLKKDDSETPHLKSLlkkevksSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELH 760
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKA-----EEAKKAEEAKIKAEEL-------KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 761 SSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDEnVRKENNKKERRLSAEKTKAEH 840
Cdd:PTZ00121 1663 AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEE-LKKAEEENKIKAEEAKKEAEE 1741
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 841 KSRRSSDSKIQKDSLGSKQHgitLQRRSESYSEDKcdmdstnmdsnLKPEEVVHKEKRRTKsllEEKLVLKSKSKTqgKQ 920
Cdd:PTZ00121 1742 DKKKAEEAKKDEEEKKKIAH---LKKEEEKKAEEI-----------RKEKEAVIEEELDEE---DEKRRMEVDKKI--KD 1802
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 921 VKVVETELQEGatkqattpkpDKEKNTEENDSekqrkskvedkpfEETGVEPVLETASSSahSTQKDSSHraklplAKEK 1000
Cdd:PTZ00121 1803 IFDNFANIIEG----------GKEGNLVINDS-------------KEMEDSAIKEVADSK--NMQLEEAD------AFEK 1851
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 1001 YKSDKDSTSTRLERKLSDGHKSRSLKHS-SKDIKKKDENKSDDKDGKEVDSSHEKARGNS 1059
Cdd:PTZ00121 1852 HKFNKNNENGEDGNKEADFNKEKDLKEDdEEEIEEADEIEKIDKDDIEREIPNNNMAGKN 1911
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
349-1168 |
5.31e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 62.30 E-value: 5.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 349 SKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSdvdGLTDITVSSVHTSDLSSFEEDTEEEVV 428
Cdd:pfam02463 175 LKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE---YLLYLDYLKLNEERIDLLQELLRDEQE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 429 TSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKsvrhayvhkpylyskyysdsDDELTVEQRRQSIAKEKEERLLRR 508
Cdd:pfam02463 252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEE--------------------LKLLAKEEEELKSELLKLERRKVD 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 509 QINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSK 588
Cdd:pfam02463 312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 589 KKQQYEEDSKETLKTSEhcEKEKISSSKELkhvHAKSEPSKPARRLSESLHVVDENKNESKIEREHKRrtstpvimegVQ 668
Cdd:pfam02463 392 LKEEELELKSEEEKEAQ--LLLELARQLED---LLKEEKKEELEILEEEEESIELKQGKLTEEKEELE----------KQ 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 669 EETDTRDvKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLK-----SLLKKEVKSSKEKPEREKTPSEDKLSVKH 743
Cdd:pfam02463 457 ELKLLKD-ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKeskarSGLKVLLALIKDGVGGRIISAHGRLGDLG 535
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 744 KYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLssdDKTERKSKHRNERKLSVLGKDGKPVSEYI---IKTDENV 820
Cdd:pfam02463 536 VAVENYKVAISTAVIVEVSATADEVEERQKLVRALTEL---PLGARKLRLLIPKLKLPLKSIAVLEIDPIlnlAQLDKAT 612
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 821 RKENNKKERRLSAEKTKAEHKSRRSSDSKiqKDSLGSKQHGITLQRRSESYSEDKcdMDSTNMDSNLKPEEVVHKEKRRT 900
Cdd:pfam02463 613 LEADEDDKRAKVVEGILKDTELTKLKESA--KAKESGLRKGVSLEEGLAEKSEVK--ASLSELTKELLEIQELQEKAESE 688
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 901 KSLLEEKLVLKSKSKTQGKQ-----------VKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETG 969
Cdd:pfam02463 689 LAKEEILRRQLEIKKKEQREkeelkklkleaEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSE 768
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 970 VEPVLETASSSAHSTQKDS----SHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDG 1045
Cdd:pfam02463 769 LSLKEKELAEEREKTEKLKveeeKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKL 848
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 1046 KEVDSshEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSG----DMTLIPEQEPME 1121
Cdd:pfam02463 849 EKLAE--EELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNlleeKENEIEERIKEE 926
|
810 820 830 840
....*....|....*....|....*....|....*....|....*..
gi 2462596362 1122 IDSEPGVENVFEVSKTQDNRNNNSQQDIDSENMKQKTSATVQKDELR 1168
Cdd:pfam02463 927 AEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
499-709 |
2.43e-03 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 43.46 E-value: 2.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 499 KEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKgqgrsSVDLEESST--KSLEPKAARIKEVlKERKVLEKKVALSKKR 576
Cdd:NF033838 186 KKAELELVKEEAKEPRDEEKIKQAKAKVESKKAE-----ATRLEKIKTdrEKAEEEAKRRADA-KLKEAVEKNVATSEQD 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 577 KKDSRnVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKhvhaksepskPARRLSESLHVVDENKNESKIEREHKR 656
Cdd:NF033838 260 KPKRR-AKRGVLGEPATPDKKENDAKSSDSSVGEETLPSPSLK----------PEKKVAEAEKKVEEAKKKAKDQKEEDR 328
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2462596362 657 RTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQkstlKNEKHLKKDDSE 709
Cdd:NF033838 329 RNYPTNTYKTLELEIAESDVKVKEAELELVKEEAKEP----RNEEKIKQAKAK 377
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COMPASS-Shg1 |
pfam05205 |
COMPASS (Complex proteins associated with Set1p) component shg1; The Shg1 subunit is one of ... |
57-150 |
2.94e-28 |
|
COMPASS (Complex proteins associated with Set1p) component shg1; The Shg1 subunit is one of the eight subunits of the COMPASS complex, complex associated with SET1, conserved in yeasts and in other eukaryotes up to humans. It is associated with the region of the Set1 protein that is N-terminal to the C-terminus, ie Set1-560-900. The function of Shg1 seems to be to slightly inhibit histone 3 lysine 4 (H3K4) di- and tri-methylation, and it is a pioneer protein. The COMPASS complex functions to methylate the fourth lysine of Histone 3 and for silencing of genes close to the telomeres of chromosomes.
Pssm-ID: 461586 [Multi-domain] Cd Length: 100 Bit Score: 110.75 E-value: 2.94e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 57 IVNHLKSQGLFDQFRRDCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGML---ESGIDR 133
Cdd:pfam05205 2 LVHEFKKKGGFDKLRKDILADFDTSDAYQNLLQRLEEIVESEVERDPSLLSKNRGKAAALIEGAIDRSDVYkkaEAGVDR 81
|
90
....*....|....*....
gi 2462596362 134 IISQVV--DPKINHTFRPQ 150
Cdd:pfam05205 82 LIDQVLdiEPKIREIRRPE 100
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
213-1059 |
3.81e-17 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 89.43 E-value: 3.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 213 QEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKE-------RTSEDMADKEKSTADSGGEGLETAPKSEEFSDlpc 285
Cdd:PTZ00121 1161 EDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDarkaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKK--- 1237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 286 PVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEktekkfDHSKKSEDTQKVKDEKQAK 365
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA------DEAKKAEEKKKADEAKKKA 1311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 366 E--KEVESLKLPSEKNSNKAKTVEGTKEDFSLIDsdvdgltditvssvhtsdlssfEEDTEEEVVTSDSMEEGEITSDDE 443
Cdd:PTZ00121 1312 EeaKKADEAKKKAEEAKKKADAAKKKAEEAKKAA----------------------EAAKAEAEAAADEAEAAEEKAEAA 1369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 444 EKNKQNKTKtqTSDSSEGKTKSVRHAYvhkpylYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKA 523
Cdd:PTZ00121 1370 EKKKEEAKK--KADAAKKKAEEKKKAD------EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE 1441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 524 EKTKSSKTKGQGRSSVDLEESSTKSLEP-KAARIKEVLKERKVLE--KKVALSKKRKKDSRNVEENSKKKQQYEEDSKET 600
Cdd:PTZ00121 1442 EAKKADEAKKKAEEAKKAEEAKKKAEEAkKADEAKKKAEEAKKADeaKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEA 1521
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 601 LKTSEHCEKEKISSSKELKhvhaKSEPSKPARRLSESLHVvdeNKNESKIEREHKRRTSTPVIMEGVQEETDTRDVKRQV 680
Cdd:PTZ00121 1522 KKADEAKKAEEAKKADEAK----KAEEKKKADELKKAEEL---KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI 1594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 681 ERSEICTEEPQKQKStlkneKHLKKDDSETPHLKSLlkkevksSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELH 760
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKA-----EEAKKAEEAKIKAEEL-------KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 761 SSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDEnVRKENNKKERRLSAEKTKAEH 840
Cdd:PTZ00121 1663 AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEE-LKKAEEENKIKAEEAKKEAEE 1741
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 841 KSRRSSDSKIQKDSLGSKQHgitLQRRSESYSEDKcdmdstnmdsnLKPEEVVHKEKRRTKsllEEKLVLKSKSKTqgKQ 920
Cdd:PTZ00121 1742 DKKKAEEAKKDEEEKKKIAH---LKKEEEKKAEEI-----------RKEKEAVIEEELDEE---DEKRRMEVDKKI--KD 1802
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 921 VKVVETELQEGatkqattpkpDKEKNTEENDSekqrkskvedkpfEETGVEPVLETASSSahSTQKDSSHraklplAKEK 1000
Cdd:PTZ00121 1803 IFDNFANIIEG----------GKEGNLVINDS-------------KEMEDSAIKEVADSK--NMQLEEAD------AFEK 1851
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 1001 YKSDKDSTSTRLERKLSDGHKSRSLKHS-SKDIKKKDENKSDDKDGKEVDSSHEKARGNS 1059
Cdd:PTZ00121 1852 HKFNKNNENGEDGNKEADFNKEKDLKEDdEEEIEEADEIEKIDKDDIEREIPNNNMAGKN 1911
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
437-1157 |
8.05e-17 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 88.27 E-value: 8.05e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 437 EITSDDEEKNKQNKTKtqtSDSSEGKTKSVRHAYVHKPYLYSKyysdSDDELTVEQRRQSIAKEKEERLlRRQINREKLE 516
Cdd:PTZ00121 1234 EAKKDAEEAKKAEEER---NNEEIRKFEEARMAHFARRQAAIK----AEEARKADELKKAEEKKKADEA-KKAEEKKKAD 1305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 517 EKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEED 596
Cdd:PTZ00121 1306 EAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK 1385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 597 SKETLKTSEHCEK---EKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKIEREHKRRTSTPVIMEGVQEETDT 673
Cdd:PTZ00121 1386 KAEEKKKADEAKKkaeEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 674 RDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSEtphLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKT 753
Cdd:PTZ00121 1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADE---AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKA 1542
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 754 gdeTELHSSEKGLKVEEniQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSA 833
Cdd:PTZ00121 1543 ---EEKKKADELKKAEE--LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE 1617
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 834 EKTKAEH----KSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSllEEKLV 909
Cdd:PTZ00121 1618 AKIKAEElkkaEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKA--AEALK 1695
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 910 LKSKSKTQGKQVKVVETElqegatkqattpkpDKEKNTEENDSEKQRKSKVEDKPFEEtgvepvlETASSSAHSTQKDSS 989
Cdd:PTZ00121 1696 KEAEEAKKAEELKKKEAE--------------EKKKAEELKKAEEENKIKAEEAKKEA-------EEDKKKAEEAKKDEE 1754
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 990 HRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRR 1069
Cdd:PTZ00121 1755 EKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKE 1834
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 1070 LCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSGDMTlipeqepmeidsEPGVENVFEVSKTQDNRNNNSQQDI 1149
Cdd:PTZ00121 1835 VADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLK------------EDDEEEIEEADEIEKIDKDDIEREI 1902
|
....*...
gi 2462596362 1150 DSENMKQK 1157
Cdd:PTZ00121 1903 PNNNMAGK 1910
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
495-1182 |
3.61e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 79.41 E-value: 3.61e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 495 QSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSK 574
Cdd:PTZ00121 1022 QNFNIEKIEELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAE 1101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 575 KRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVH-----AKSEPSKPARRLSESLHVVDENKNESK 649
Cdd:PTZ00121 1102 EAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEdakrvEIARKAEDARKAEEARKAEDAKKAEAA 1181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 650 IEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHL-KSLLKKEVKSSKEKP 728
Cdd:PTZ00121 1182 RKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAeEERNNEEIRKFEEAR 1261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 729 EREKTPSEDKLSVKHKYKGDCMHKTGDET---ELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNErklsvlgkD 805
Cdd:PTZ00121 1262 MAHFARRQAAIKAEEARKADELKKAEEKKkadEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAD--------A 1333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 806 GKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHgitlQRRSESYSEDKCDMDSTnmds 885
Cdd:PTZ00121 1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAE----EKKKADEAKKKAEEDKK---- 1405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 886 nlKPEEVVHKEKRRTKSlLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKE--KNTEENDSEKQRKSKVEDK 963
Cdd:PTZ00121 1406 --KADELKKAAAAKKKA-DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEakKKAEEAKKADEAKKKAEEA 1482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 964 PFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDK 1043
Cdd:PTZ00121 1483 KKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEE 1562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 1044 DGKEVDSSHEKARGNSSLMEKKLSRRLcENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKksgdmtLIPEQEPMEID 1123
Cdd:PTZ00121 1563 KKKAEEAKKAEEDKNMALRKAEEAKKA-EEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE------LKKAEEEKKKV 1635
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 1124 SEPGVENVFEVSKTQDNRNNNSQQDIDSENMKQKTSATVQK-DELRTCTADSKATAPAYK 1182
Cdd:PTZ00121 1636 EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKaEEAKKAEEDEKKAAEALK 1695
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
491-1087 |
1.48e-12 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 74.41 E-value: 1.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 491 EQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSvdlEESSTKSLEPKAARIKEVLKERKVLEKKV 570
Cdd:PTZ00121 1113 EARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKA---EDARKAEEARKAEDAKKAEAARKAEEVRK 1189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 571 ALSKKRKKDSRNVEENSKkkqqYEEDSK-ETLKTSEhcEKEKISSSKELKHVHAKSEPSKPAR--------RLSESLHVV 641
Cdd:PTZ00121 1190 AEELRKAEDARKAEAARK----AEEERKaEEARKAE--DAKKAEAVKKAEEAKKDAEEAKKAEeernneeiRKFEEARMA 1263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 642 DENKNESKIEREHKRRTSTPVIMEGVQ--EETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSEtphLKSLLKK 719
Cdd:PTZ00121 1264 HFARRQAAIKAEEARKADELKKAEEKKkaDEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADA---AKKKAEE 1340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 720 EVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKglKVEENIQKQSQQTKLSSDDKTERKSKHRNERKL 799
Cdd:PTZ00121 1341 AKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK--KAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 800 SvlGKDGKPVSEYIIKTDENVRKENNKKE----RRLSAEKTKAEHKSRRSSDSKIQ---KDSLGSKQHGITLQRRSESyS 872
Cdd:PTZ00121 1419 K--ADEAKKKAEEKKKADEAKKKAEEAKKadeaKKKAEEAKKAEEAKKKAEEAKKAdeaKKKAEEAKKADEAKKKAEE-A 1495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 873 EDKCDMDSTNMDSNLKPEEVVH-KEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEEND 951
Cdd:PTZ00121 1496 KKKADEAKKAAEAKKKADEAKKaEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED 1575
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 952 SEKQRKSKVEDKPFEETGVEPVL----ETASSSAHSTQKDSSHRAKLPLAKeKYKSDKDSTSTRLERKLSDGHKSRSLKH 1027
Cdd:PTZ00121 1576 KNMALRKAEEAKKAEEARIEEVMklyeEEKKMKAEEAKKAEEAKIKAEELK-KAEEEKKKVEQLKKKEAEEKKKAEELKK 1654
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462596362 1028 SSKD--IKKKDENKSDDKDGKEVD----SSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEE 1087
Cdd:PTZ00121 1655 AEEEnkIKAAEEAKKAEEDKKKAEeakkAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEE 1720
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
213-879 |
6.36e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 65.55 E-value: 6.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 213 QEASAARASTETSNA----KTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVE 288
Cdd:PTZ00121 1290 KKADEAKKAEEKKKAdeakKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA 1369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 289 EIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKvKDEKQAKEKE 368
Cdd:PTZ00121 1370 EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK-KAEEAKKADE 1448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 369 VESLKLPSEKNSNKAKTVEGTKEdfslidsdVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDD----EE 444
Cdd:PTZ00121 1449 AKKKAEEAKKAEEAKKKAEEAKK--------ADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEakkaEE 1520
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 445 KNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQsiAKEKEERLLRRQINREKLEEKRKQKAE 524
Cdd:PTZ00121 1521 AKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKK--AEEDKNMALRKAEEAKKAEEARIEEVM 1598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 525 KTKSSKTKGQGRSSVDLEESSTKSLEPKAAriKEVLKERKVLEKKVALSKKRKKDSRNVEENSK-KKQQYEEDSKETLKT 603
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKA--EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKiKAAEEAKKAEEDKKK 1676
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 604 SEHCEKEKISSSKELKHVHAKSEPSKPARRLseslhvvdenkneSKIEREHKRRtSTPVIMEGVQEETDTRDVKRQVERS 683
Cdd:PTZ00121 1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEEL-------------KKKEAEEKKK-AEELKKAEEENKIKAEEAKKEAEED 1742
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 684 EICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKY-----------KGDCMHK 752
Cdd:PTZ00121 1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFdnfaniieggkEGNLVIN 1822
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 753 TGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKP-VSEYIIKTDENVRKENNKKERRL 831
Cdd:PTZ00121 1823 DSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEdDEEEIEEADEIEKIDKDDIEREI 1902
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 2462596362 832 SAEKTKAehKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMD 879
Cdd:PTZ00121 1903 PNNNMAG--KNNDIIDDKLDKDEYIKRDAEETREEIIKISKKDMCIND 1948
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
349-1168 |
5.31e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 62.30 E-value: 5.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 349 SKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSdvdGLTDITVSSVHTSDLSSFEEDTEEEVV 428
Cdd:pfam02463 175 LKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE---YLLYLDYLKLNEERIDLLQELLRDEQE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 429 TSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKsvrhayvhkpylyskyysdsDDELTVEQRRQSIAKEKEERLLRR 508
Cdd:pfam02463 252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEE--------------------LKLLAKEEEELKSELLKLERRKVD 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 509 QINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSK 588
Cdd:pfam02463 312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 589 KKQQYEEDSKETLKTSEhcEKEKISSSKELkhvHAKSEPSKPARRLSESLHVVDENKNESKIEREHKRrtstpvimegVQ 668
Cdd:pfam02463 392 LKEEELELKSEEEKEAQ--LLLELARQLED---LLKEEKKEELEILEEEEESIELKQGKLTEEKEELE----------KQ 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 669 EETDTRDvKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLK-----SLLKKEVKSSKEKPEREKTPSEDKLSVKH 743
Cdd:pfam02463 457 ELKLLKD-ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKeskarSGLKVLLALIKDGVGGRIISAHGRLGDLG 535
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 744 KYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLssdDKTERKSKHRNERKLSVLGKDGKPVSEYI---IKTDENV 820
Cdd:pfam02463 536 VAVENYKVAISTAVIVEVSATADEVEERQKLVRALTEL---PLGARKLRLLIPKLKLPLKSIAVLEIDPIlnlAQLDKAT 612
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 821 RKENNKKERRLSAEKTKAEHKSRRSSDSKiqKDSLGSKQHGITLQRRSESYSEDKcdMDSTNMDSNLKPEEVVHKEKRRT 900
Cdd:pfam02463 613 LEADEDDKRAKVVEGILKDTELTKLKESA--KAKESGLRKGVSLEEGLAEKSEVK--ASLSELTKELLEIQELQEKAESE 688
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 901 KSLLEEKLVLKSKSKTQGKQ-----------VKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETG 969
Cdd:pfam02463 689 LAKEEILRRQLEIKKKEQREkeelkklkleaEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSE 768
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 970 VEPVLETASSSAHSTQKDS----SHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDG 1045
Cdd:pfam02463 769 LSLKEKELAEEREKTEKLKveeeKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKL 848
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 1046 KEVDSshEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSG----DMTLIPEQEPME 1121
Cdd:pfam02463 849 EKLAE--EELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNlleeKENEIEERIKEE 926
|
810 820 830 840
....*....|....*....|....*....|....*....|....*..
gi 2462596362 1122 IDSEPGVENVFEVSKTQDNRNNNSQQDIDSENMKQKTSATVQKDELR 1168
Cdd:pfam02463 927 AEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
476-1089 |
1.02e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 51.26 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 476 LYSKYYSDSDdelTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKssktkGQGRSSVDLEESSTKSlepkaar 555
Cdd:pfam05483 79 LYSKLYKEAE---KIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQF-----ENEKVSLKLEEEIQEN------- 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 556 iKEVLKERKVLEKKVALSKKrkKDSRNVEENskKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLS 635
Cdd:pfam05483 144 -KDLIKENNATRHLCNLLKE--TCARSAEKT--KKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLK 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 636 ESLHVVDENKNESKIEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEicTEEPQKQKSTLKNEKHLKKDDSETPHLKS 715
Cdd:pfam05483 219 EDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESR--DKANQLEEKTKLQDENLKELIEKKDHLTK 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 716 LLKKEVKSSKEKPEREKTPSEDklsVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDD--KTERKSKH 793
Cdd:pfam05483 297 ELEDIKMSLQRSMSTQKALEED---LQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEllRTEQQRLE 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 794 RNERKLSVLGKDGKPVSEyiiKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQK--DSLGSKQHGIT--LQRRSE 869
Cdd:pfam05483 374 KNEDQLKIITMELQKKSS---ELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKiaEELKGKEQELIflLQAREK 450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 870 SYSEDKCDMDSTNMDsnlkpEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEE 949
Cdd:pfam05483 451 EIHDLEIQLTAIKTS-----EEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINC 525
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 950 NDSEKQRKSKVEDKPFEETGVEPVLETASSSAhsTQKDSSHRAKLPlakekyKSDKDSTSTRLErKLSDGHKSRSLKHSS 1029
Cdd:pfam05483 526 KKQEERMLKQIENLEEKEMNLRDELESVREEF--IQKGDEVKCKLD------KSEENARSIEYE-VLKKEKQMKILENKC 596
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 1030 KDIKKKDENKSddKDGKEVDSSHEKARGNSSLMEKKLSrrLCENRRGSLSQEMAKGEEKL 1089
Cdd:pfam05483 597 NNLKKQIENKN--KNIEELHQENKALKKKGSAENKQLN--AYEIKVNKLELELASAKQKF 652
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
494-1081 |
1.31e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 51.13 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 494 RQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKgqgrssvDLEESSTKSLEPKAARIKEVLKERKVLEKKVALS 573
Cdd:pfam02463 145 EIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETE-------NLAELIIDLEELKLQELKLKEQAKKALEYYQLKE 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 574 KKRKKDS-----RNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNES 648
Cdd:pfam02463 218 KLELEEEyllylDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEE 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 649 KIErehkrrtstpvimEGVQEETDTRDVKRQVERSEictEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKP 728
Cdd:pfam02463 298 LKS-------------ELLKLERRKVDDEEKLKESE---KEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEEL 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 729 EREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKP 808
Cdd:pfam02463 362 EKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIEL 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 809 VSEYIIKTDENVRKENNKK-ERRLSAEKTKAEHKSRRSSDSKIQKDslgsKQHGITLQRRSESYSEDKCDMDSTNMDSNL 887
Cdd:pfam02463 442 KQGKLTEEKEELEKQELKLlKDELELKKSEDLLKETQLVKLQEQLE----LLLSRQKLEERSQKESKARSGLKVLLALIK 517
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 888 KPEEVVHKEKRRTKSLLEEKLVLKS--KSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPF 965
Cdd:pfam02463 518 DGVGGRIISAHGRLGDLGVAVENYKvaISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVL 597
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 966 EetgVEPVLETASSSAHSTQKDS-SHRAKLPLAKEKYKsDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKD 1044
Cdd:pfam02463 598 E---IDPILNLAQLDKATLEADEdDKRAKVVEGILKDT-ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTK 673
|
570 580 590
....*....|....*....|....*....|....*..
gi 2462596362 1045 GKEVdSSHEKARGNSSLMEKKLSRRLCENRRGSLSQE 1081
Cdd:pfam02463 674 ELLE-IQELQEKAESELAKEEILRRQLEIKKKEQREK 709
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
767-1054 |
3.01e-05 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 50.04 E-value: 3.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 767 KVEENIQKQSQQtklssDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDenvrkenNKKERRLSAEKTKAEHKSRRSS 846
Cdd:PTZ00108 1136 KFEEALEEQEEV-----EEKEIAKEQRLKSKTKGKASKLRKPKLKKKEKKK-------KKSSADKSKKASVVGNSKRVDS 1203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 847 DSKIQKDSLGSKqhgiTLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVET 926
Cdd:PTZ00108 1204 DEKRKLDDKPDN----KKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVS 1279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 927 ELQEGATKQATTPKPDKEKNTEENDSEKQRKskveDKPFEETGVEPVLETASSSAHSTQKDSshraklplaKEKYKSDKD 1006
Cdd:PTZ00108 1280 AVQYSPPPPSKRPDGESNGGSKPSSPTKKKV----KKRLEGSLAALKKKKKSEKKTARKKKS---------KTRVKQASA 1346
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2462596362 1007 STSTRLERKLSdghksrslKHSSKDIKKKDENKSDDKDGKEVDSSHEK 1054
Cdd:PTZ00108 1347 SQSSRLLRRPR--------KKKSDSSSEDDDDSEVDDSEDEDDEDDED 1386
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
288-999 |
1.61e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 44.19 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 288 EEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEkkfdhSKKSEDTQKVKDEKQAKEK 367
Cdd:pfam02463 278 EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE-----KEEIEELEKELKELEIKRE 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 368 EVESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTsdLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNK 447
Cdd:pfam02463 353 AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE--LKSEEEKEAQLLLELARQLEDLLKEEKKEELE 430
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 448 QNKTKTQTSDSSEGKTKSVRHayvHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTK 527
Cdd:pfam02463 431 ILEEEEESIELKQGKLTEEKE---ELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARS 507
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 528 SSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALS--KKRKKDSRNVEENSKKKQQYEEDSKETLKTSE 605
Cdd:pfam02463 508 GLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVsaTADEVEERQKLVRALTELPLGARKLRLLIPKL 587
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 606 HCEKEKISsskELKHVHAKSEPSKPARRLSESLHVVDENKNE--SKIEREHKRRTSTPVIMEGVQEetDTRDVKRQVERS 683
Cdd:pfam02463 588 KLPLKSIA---VLEIDPILNLAQLDKATLEADEDDKRAKVVEgiLKDTELTKLKESAKAKESGLRK--GVSLEEGLAEKS 662
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 684 EICTEEPQKQKSTLKNEKHLKKDDSETphLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKykgdcmhktGDETELHSSE 763
Cdd:pfam02463 663 EVKASLSELTKELLEIQELQEKAESEL--AKEEILRRQLEIKKKEQREKEELKKLKLEAEE---------LLADRVQEAQ 731
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 764 KGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEhKSR 843
Cdd:pfam02463 732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE-EEL 810
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 844 RSSDSKIQKDSLGSKQHG-----ITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQG 918
Cdd:pfam02463 811 KEEAELLEEEQLLIEQEEkikeeELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELES 890
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 919 KQVKVV-ETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLA 997
Cdd:pfam02463 891 KEEKEKeEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKE 970
|
..
gi 2462596362 998 KE 999
Cdd:pfam02463 971 EL 972
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
486-1068 |
2.01e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.90 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 486 DELTVEQRRQSIAKEKEERLLRRQIN--REKLE--EKRKQKAEKTKSSKTKGQGRssvdleessTKSLEPKAARIKEVLK 561
Cdd:PRK03918 192 EELIKEKEKELEEVLREINEISSELPelREELEklEKEVKELEELKEEIEELEKE---------LESLEGSKRKLEEKIR 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 562 E-RKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSK---ETLKTSEHCEKEKISSSKELKHVHAK-SEPSKPARRLSE 636
Cdd:PRK03918 263 ElEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEfyeEYLDELREIEKRLSRLEEEINGIEERiKELEEKEERLEE 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 637 SLhvvdenKNESKIEREHKRrtstpvIMEGVQEETDTRDVKRQVER--SEICTEEPQKQKSTLKNEKHLKKDDSEtpHLK 714
Cdd:PRK03918 343 LK------KKLKELEKRLEE------LEERHELYEEAKAKKEELERlkKRLTGLTPEKLEKELEELEKAKEEIEE--EIS 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 715 SLLKKEVKSSKEKPEREKTPSEDKlsvkhKYKGDCMHKTGDETELHssEKGLKVEENIQKQSQQTKLSSDDKTERKSKhR 794
Cdd:PRK03918 409 KITARIGELKKEIKELKKAIEELK-----KAKGKCPVCGRELTEEH--RKELLEEYTAELKRIEKELKEIEEKERKLR-K 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 795 NERKLsvlgkdgkpvseyiiktdENVRkennKKERRLSAEKTKAEH-KSRRSSDSKIQKDSlgskqhgitLQRRSESYSE 873
Cdd:PRK03918 481 ELREL------------------EKVL----KKESELIKLKELAEQlKELEEKLKKYNLEE---------LEKKAEEYEK 529
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 874 -----DKCDMDSTNMDSNLKPEEVVHKEKR---RTKSLLEEKL--VLKSKSKTQGKQVKVVETELQ--EGATKQATTPKP 941
Cdd:PRK03918 530 lkeklIKLKGEIKSLKKELEKLEELKKKLAeleKKLDELEEELaeLLKELEELGFESVEELEERLKelEPFYNEYLELKD 609
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 942 DKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSShraklplaKEKYKSDKDSTsTRLERKLSdghk 1021
Cdd:PRK03918 610 AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS--------EEEYEELREEY-LELSRELA---- 676
|
570 580 590 600
....*....|....*....|....*....|....*....|....*...
gi 2462596362 1022 srSLKHSSKDIKK-KDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSR 1068
Cdd:PRK03918 677 --GLRAELEELEKrREEIKKTLEKLKEELEEREKAKKELEKLEKALER 722
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
499-709 |
2.43e-03 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 43.46 E-value: 2.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 499 KEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKgqgrsSVDLEESST--KSLEPKAARIKEVlKERKVLEKKVALSKKR 576
Cdd:NF033838 186 KKAELELVKEEAKEPRDEEKIKQAKAKVESKKAE-----ATRLEKIKTdrEKAEEEAKRRADA-KLKEAVEKNVATSEQD 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 577 KKDSRnVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKhvhaksepskPARRLSESLHVVDENKNESKIEREHKR 656
Cdd:NF033838 260 KPKRR-AKRGVLGEPATPDKKENDAKSSDSSVGEETLPSPSLK----------PEKKVAEAEKKVEEAKKKAKDQKEEDR 328
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2462596362 657 RTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQkstlKNEKHLKKDDSE 709
Cdd:NF033838 329 RNYPTNTYKTLELEIAESDVKVKEAELELVKEEAKEP----RNEEKIKQAKAK 377
|
|
| CR6_interact |
pfam10147 |
Growth arrest and DNA-damage-inducible proteins-interacting protein 1; Members of this family ... |
489-589 |
8.05e-03 |
|
Growth arrest and DNA-damage-inducible proteins-interacting protein 1; Members of this family of proteins act as negative regulators of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occur also in the absence of GADD45 proteins. Furthermore, they act as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity.
Pssm-ID: 431088 [Multi-domain] Cd Length: 204 Bit Score: 40.22 E-value: 8.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462596362 489 TVEQRRQSIAKEKEERLLRRQINREKLEEK-------------RKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAAR 555
Cdd:pfam10147 88 SLAQMLESNRAQKAEKEARRQAREQEIAKKmakmpqwiadwnaQKAKREAEAQAAKERKERLVAEAREHFGFKVDPRDER 167
|
90 100 110
....*....|....*....|....*....|....*
gi 2462596362 556 IKEVLKERKVLEKK-VALSKKRKKDSRNVEENSKK 589
Cdd:pfam10147 168 FKEMLQQKEKEDKKkVKEAKRKEKEEKRMAKLVEA 202
|
|
| |
