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Conserved domains on  [gi|2462571778|ref|XP_054197317|]
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glucosylceramide transporter ABCA12 isoform X1 [Homo sapiens]

Protein Classification

ABC transporter A family member( domain architecture ID 1000606)

ABC transporter A family member (ABCA) may mediate the transport of a variety of lipid compounds

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
rim_protein super family cl31083
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
752-2579 0e+00

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


The actual alignment was detected with superfamily member TIGR01257:

Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 1233.73  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  752 NHTKDFLTYKLTKEQIAskYGIPINTTPFCFSLYKDIINMPAGPVIWAFLKPMLLGRILYAPYNPVTKAIMEKSNVTLRQ 831
Cdd:TIGR01257  343 NNYKAFLGIDSTRKDPI--YSYDKRTTSFCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARRILKNANSTFEE 420
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  832 LAELREKSQEWMDKSPLFMNSFHLLNQaIPMLQNTLRNPFVQVFVKFSVGLDAV--ELL----------KQIDELDILRL 899
Cdd:TIGR01257  421 LERVRKLVKAWEEVGPQIWYFFDKSTQ-MTMIRDTLQNPTVKDFINRQLGEEGItaEAVlnflyngpreKQADDMTNFDW 499
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  900 KlenniDIIDQLNTLSSLTVNISSCVLYDRIQAAKTIDEMEREAKRLYKSNELFGSVIFklPSNRSWHRGydsgnvfLPP 979
Cdd:TIGR01257  500 R-----DIFNITDRFLRLANQYLECLVLDKFESYDDEVQLTQRALSLLEENRFWAGVVF--PDMYPWTSS-------LPP 565
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  980 VIKYTIRMSLKTAQTTRSLRTKIWAPGPHNSPSHN--QIYGrAFIYLQDSIERAIIELQTgRNSQEIAVQVQAIPYPCFM 1057
Cdd:TIGR01257  566 HVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDfrYIWG-GFAYLQDMVEQGITRSQM-QAEPPVGIYLQQMPYPCFV 643
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1058 KDNFLTSVSYSLPIVLMVAWVVFIAAFVKKLVYEKDLRLHEYMKMMGVNSCSHFFAWLIESVGFLLVTIVILIIILKFGN 1137
Cdd:TIGR01257  644 DDSFMIILNRCFPIFMVLAWIYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR 723
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1138 ILPKTNGFILFLYFSDYSFSVIAMSYLISVFFNNTNIAALIGSLIYIIAFFPFIVLVTVENELSYVLKVFMSLLSPTAFS 1217
Cdd:TIGR01257  724 ILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQDRMTADLKTAVSLLSPVAFG 803
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1218 YASQYIARYEEQGIGLQWENMYTSPVQDDTTSFGWLCCLILADSFIYFLIAWYVRNVFPGTYGMAAPWYFPILPSYWKER 1297
Cdd:TIGR01257  804 FGTEYLVRFEEQGLGLQWSNIGNSPLEGDEFSFLLSMKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGG 883
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1298 FGCAeVKPEKSnglmftnimMQNTNPSASKTS----PEYMFSSNIEPEPKDLTVGVALHGVTKIY--GSKVAVDNLNLNF 1371
Cdd:TIGR01257  884 EGCS-TREERA---------LEKTEPLTEEMEdpehPEGINDSFFERELPGLVPGVCVKNLVKIFepSGRPAVDRLNITF 953
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1372 YEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVP 1451
Cdd:TIGR01257  954 YENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGR 1033
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1452 HWTKKQLheEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTAR 1531
Cdd:TIGR01257 1034 SWEEAQL--EMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGR 1111
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1532 TIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFGDGYHLTLTKK----KSPNLNANAVC-------------- 1593
Cdd:TIGR01257 1112 TIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKmkniQSQRGGCEGTCsctskgfstrcpar 1191
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1594 ------------DTMAVTAMIQSHLPEAYLKEDIGGELVYVLPPFSTKvSGAYLSLLRALDNGMGDLNIGCYGISDTTVE 1661
Cdd:TIGR01257 1192 vdeitpeqvldgDVNELMDLVYHHVPEAKLVECIGQELIFLLPNKNFK-QRAYASLFRELEETLADLGLSSFGISDTPLE 1270
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1662 EVFLNLTKES-----------QKNSAMSLEH----LTQKKIGNSNANGISTPDDLSVSSSN--FTDRDDKiltrGERLD- 1723
Cdd:TIGR01257 1271 EIFLKVTEDAdsgslfaggaqQKRENANLRHpcsgPTEKAGQTPQASHTCSPGQPAAHPEGqpPPEPEDP----GVPLNt 1346
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1724 GFGLLLKKIMAILIKRFHHTRRNWKGLIAQVILPIVFVTTAMGLGTLRNSSNSYPEIQISPSLYGtsEQTAFYANYHPST 1803
Cdd:TIGR01257 1347 GARLILQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPALTLHPWMYG--QQYTFFSMDEPNS 1424
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1804 E---ALVSAMWDFPGIDNMCLNTS---DLQCLNKDSL---------------EKWnTSGEPITNfgvCSCSEN-----VQ 1857
Cdd:TIGR01257 1425 EhleVLADVLLNKPGFGNRCLKEEwlpEYPCGNSTPWktpsvspnithlfqkQKW-TAAHPSPS---CRCSTRekltmLP 1500
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1858 ECPK--FNYSPPHRRTYSSQVIYNLTGQRVENYLISTANEFV-----------QKRYGGWSFG-----LPLT-------- 1911
Cdd:TIGR01257 1501 ECPEgaGGLPPPQRTQRSTEILQDLTDRNISDFLVKTYPALIrsslkskfwvnEQRYGGISIGgklpaIPITgealvgfl 1580
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1912 KDL--RFDITGVPANRTLA----------------KVWYDPEGYHSLPAYLNSLNNFLLRVNMSK-YDAARHGIIMYSHP 1972
Cdd:TIGR01257 1581 SDLgqMMNVSGGPVTREASkempdflkhletedniKVWFNNKGWHALVSFLNVAHNAILRASLPKdRDPEEYGITVISQP 1660
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1973 YPGVQDQ--EQATISSLIDILVALSILMGYSVTTASFVTYVVREHQTKAKQLQHISGIGVTCYWVTNFIYDMVFYLVPVA 2050
Cdd:TIGR01257 1661 LNLTKEQlsEITVLTTSVDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFISGVSPTTYWLTNFLWDIMNYAVSAG 1740
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2051 FSIGIIAIFKLPAFYSENNLGAVSLLLLLFGYATFSWMYLLAGLFHETGMAFITYVCVNLFFGINSivslSVVYFLSKEK 2130
Cdd:TIGR01257 1741 LVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINS----SAITFVLELF 1816
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2131 PNDPTLELISETLKRIFLIFPQFCFGYGLIELSQQQSVLDFLKAYGVEYPNETFEMNKLGAMFVALVSQGTMFFSLRLLI 2210
Cdd:TIGR01257 1817 ENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDVYAQFGEEHSANPFQWDLIGKNLVAMAVEGVVYFLLTLLI 1896
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2211 NEslikklRLFFRKFNSSHVRETI-DEDEDVRAERLRVESGAAEFDLVQLYCLTKTYQLIHKKiiAVNNISIGIPAGECF 2289
Cdd:TIGR01257 1897 QH------HFFLSRWIAEPAKEPIfDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGTSSP--AVDRLCVGVRPGECF 1968
                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2290 GLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLvGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDI 2369
Cdd:TIGR01257 1969 GLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVHQNM-GYCPQFDAIDDLLTGREHLYLYARLRGVPAEEI 2047
                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2370 KETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTS 2449
Cdd:TIGR01257 2048 EKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTS 2127
                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2450 HSMEECEALCTRLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNK----VTMETLTKFMQLHFPKTYLKDQHLSMLE 2525
Cdd:TIGR01257 2128 HSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSPKddllPDLNPVEQFFQGNFPGSVQRERHYNMLQ 2207
                         1930      1940      1950      1960      1970
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 2526 YHVPVTAggVANIFDLLETNKTALNITNFLVSQTTLEEVFINFAKDQKsyETAD 2579
Cdd:TIGR01257 2208 FQVSSSS--LARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQT--ETYD 2257
rim_protein super family cl31083
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
7-86 1.00e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


The actual alignment was detected with superfamily member TIGR01257:

Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 71.20  E-value: 1.00e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778    7 QLQILVWKNWLGVKRQPLWTLVLILWPVIIFIILAITRTKFPPTAKPTCYLAPRNLPSTGFFPFLQTLLCDTDSKCKDTP 86
Cdd:TIGR01257    6 QIQLLLWKNWTLRKRQKIRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCFQSP 85
 
Name Accession Description Interval E-value
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
752-2579 0e+00

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 1233.73  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  752 NHTKDFLTYKLTKEQIAskYGIPINTTPFCFSLYKDIINMPAGPVIWAFLKPMLLGRILYAPYNPVTKAIMEKSNVTLRQ 831
Cdd:TIGR01257  343 NNYKAFLGIDSTRKDPI--YSYDKRTTSFCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARRILKNANSTFEE 420
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  832 LAELREKSQEWMDKSPLFMNSFHLLNQaIPMLQNTLRNPFVQVFVKFSVGLDAV--ELL----------KQIDELDILRL 899
Cdd:TIGR01257  421 LERVRKLVKAWEEVGPQIWYFFDKSTQ-MTMIRDTLQNPTVKDFINRQLGEEGItaEAVlnflyngpreKQADDMTNFDW 499
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  900 KlenniDIIDQLNTLSSLTVNISSCVLYDRIQAAKTIDEMEREAKRLYKSNELFGSVIFklPSNRSWHRGydsgnvfLPP 979
Cdd:TIGR01257  500 R-----DIFNITDRFLRLANQYLECLVLDKFESYDDEVQLTQRALSLLEENRFWAGVVF--PDMYPWTSS-------LPP 565
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  980 VIKYTIRMSLKTAQTTRSLRTKIWAPGPHNSPSHN--QIYGrAFIYLQDSIERAIIELQTgRNSQEIAVQVQAIPYPCFM 1057
Cdd:TIGR01257  566 HVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDfrYIWG-GFAYLQDMVEQGITRSQM-QAEPPVGIYLQQMPYPCFV 643
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1058 KDNFLTSVSYSLPIVLMVAWVVFIAAFVKKLVYEKDLRLHEYMKMMGVNSCSHFFAWLIESVGFLLVTIVILIIILKFGN 1137
Cdd:TIGR01257  644 DDSFMIILNRCFPIFMVLAWIYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR 723
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1138 ILPKTNGFILFLYFSDYSFSVIAMSYLISVFFNNTNIAALIGSLIYIIAFFPFIVLVTVENELSYVLKVFMSLLSPTAFS 1217
Cdd:TIGR01257  724 ILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQDRMTADLKTAVSLLSPVAFG 803
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1218 YASQYIARYEEQGIGLQWENMYTSPVQDDTTSFGWLCCLILADSFIYFLIAWYVRNVFPGTYGMAAPWYFPILPSYWKER 1297
Cdd:TIGR01257  804 FGTEYLVRFEEQGLGLQWSNIGNSPLEGDEFSFLLSMKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGG 883
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1298 FGCAeVKPEKSnglmftnimMQNTNPSASKTS----PEYMFSSNIEPEPKDLTVGVALHGVTKIY--GSKVAVDNLNLNF 1371
Cdd:TIGR01257  884 EGCS-TREERA---------LEKTEPLTEEMEdpehPEGINDSFFERELPGLVPGVCVKNLVKIFepSGRPAVDRLNITF 953
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1372 YEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVP 1451
Cdd:TIGR01257  954 YENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGR 1033
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1452 HWTKKQLheEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTAR 1531
Cdd:TIGR01257 1034 SWEEAQL--EMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGR 1111
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1532 TIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFGDGYHLTLTKK----KSPNLNANAVC-------------- 1593
Cdd:TIGR01257 1112 TIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKmkniQSQRGGCEGTCsctskgfstrcpar 1191
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1594 ------------DTMAVTAMIQSHLPEAYLKEDIGGELVYVLPPFSTKvSGAYLSLLRALDNGMGDLNIGCYGISDTTVE 1661
Cdd:TIGR01257 1192 vdeitpeqvldgDVNELMDLVYHHVPEAKLVECIGQELIFLLPNKNFK-QRAYASLFRELEETLADLGLSSFGISDTPLE 1270
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1662 EVFLNLTKES-----------QKNSAMSLEH----LTQKKIGNSNANGISTPDDLSVSSSN--FTDRDDKiltrGERLD- 1723
Cdd:TIGR01257 1271 EIFLKVTEDAdsgslfaggaqQKRENANLRHpcsgPTEKAGQTPQASHTCSPGQPAAHPEGqpPPEPEDP----GVPLNt 1346
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1724 GFGLLLKKIMAILIKRFHHTRRNWKGLIAQVILPIVFVTTAMGLGTLRNSSNSYPEIQISPSLYGtsEQTAFYANYHPST 1803
Cdd:TIGR01257 1347 GARLILQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPALTLHPWMYG--QQYTFFSMDEPNS 1424
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1804 E---ALVSAMWDFPGIDNMCLNTS---DLQCLNKDSL---------------EKWnTSGEPITNfgvCSCSEN-----VQ 1857
Cdd:TIGR01257 1425 EhleVLADVLLNKPGFGNRCLKEEwlpEYPCGNSTPWktpsvspnithlfqkQKW-TAAHPSPS---CRCSTRekltmLP 1500
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1858 ECPK--FNYSPPHRRTYSSQVIYNLTGQRVENYLISTANEFV-----------QKRYGGWSFG-----LPLT-------- 1911
Cdd:TIGR01257 1501 ECPEgaGGLPPPQRTQRSTEILQDLTDRNISDFLVKTYPALIrsslkskfwvnEQRYGGISIGgklpaIPITgealvgfl 1580
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1912 KDL--RFDITGVPANRTLA----------------KVWYDPEGYHSLPAYLNSLNNFLLRVNMSK-YDAARHGIIMYSHP 1972
Cdd:TIGR01257 1581 SDLgqMMNVSGGPVTREASkempdflkhletedniKVWFNNKGWHALVSFLNVAHNAILRASLPKdRDPEEYGITVISQP 1660
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1973 YPGVQDQ--EQATISSLIDILVALSILMGYSVTTASFVTYVVREHQTKAKQLQHISGIGVTCYWVTNFIYDMVFYLVPVA 2050
Cdd:TIGR01257 1661 LNLTKEQlsEITVLTTSVDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFISGVSPTTYWLTNFLWDIMNYAVSAG 1740
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2051 FSIGIIAIFKLPAFYSENNLGAVSLLLLLFGYATFSWMYLLAGLFHETGMAFITYVCVNLFFGINSivslSVVYFLSKEK 2130
Cdd:TIGR01257 1741 LVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINS----SAITFVLELF 1816
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2131 PNDPTLELISETLKRIFLIFPQFCFGYGLIELSQQQSVLDFLKAYGVEYPNETFEMNKLGAMFVALVSQGTMFFSLRLLI 2210
Cdd:TIGR01257 1817 ENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDVYAQFGEEHSANPFQWDLIGKNLVAMAVEGVVYFLLTLLI 1896
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2211 NEslikklRLFFRKFNSSHVRETI-DEDEDVRAERLRVESGAAEFDLVQLYCLTKTYQLIHKKiiAVNNISIGIPAGECF 2289
Cdd:TIGR01257 1897 QH------HFFLSRWIAEPAKEPIfDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGTSSP--AVDRLCVGVRPGECF 1968
                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2290 GLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLvGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDI 2369
Cdd:TIGR01257 1969 GLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVHQNM-GYCPQFDAIDDLLTGREHLYLYARLRGVPAEEI 2047
                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2370 KETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTS 2449
Cdd:TIGR01257 2048 EKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTS 2127
                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2450 HSMEECEALCTRLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNK----VTMETLTKFMQLHFPKTYLKDQHLSMLE 2525
Cdd:TIGR01257 2128 HSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSPKddllPDLNPVEQFFQGNFPGSVQRERHYNMLQ 2207
                         1930      1940      1950      1960      1970
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 2526 YHVPVTAggVANIFDLLETNKTALNITNFLVSQTTLEEVFINFAKDQKsyETAD 2579
Cdd:TIGR01257 2208 FQVSSSS--LARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQT--ETYD 2257
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
2257-2480 6.87e-98

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 314.83  E-value: 6.87e-98
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2257 VQLYCLTKTYqliHKKI-IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrNKTGSLGHVDSHSSL 2335
Cdd:cd03263      1 LQIRNLTKTY---KKGTkPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYI-NGYSIRTDRKAARQS 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2336 VGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILL 2415
Cdd:cd03263     77 LGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLL 156
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2416 LDEPSSGMDPKSKRHLWKIISEEVQNKcSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIK 2480
Cdd:cd03263    157 LDEPTSGLDPASRRAIWDLILEVRKGR-SIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
1349-1584 1.47e-78

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 260.00  E-value: 1.47e-78
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQ 1428
Cdd:COG1131      1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRRIGYVPQ 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHLLLYGSIK-VPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDE 1507
Cdd:COG1131     81 EPALYPDLTVRENLRFFARLYgLP---RKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDE 157
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1508 PSTGVDPCSRRSIWDVISKNKTA-RTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFGDGYHLTLTKKKS 1584
Cdd:COG1131    158 PTSGLDPEARRELWELLRELAAEgKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARLLEDVFLELTGEEA 235
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
1346-1567 4.45e-42

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 158.84  E-value: 4.45e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1346 TVGVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGV 1425
Cdd:PRK13536    39 TVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLARARIGV 118
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1426 CMQHDVLFSYLTTKEHLLLYGsiKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVIL 1505
Cdd:PRK13536   119 VPQFDNLDLEFTVRENLLVFG--RYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLIL 196
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1506 DEPSTGVDPCSRRSIWDVI-SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYL 1567
Cdd:PRK13536   197 DEPTTGLDPHARHLIWERLrSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHAL 259
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
2276-2421 1.68e-35

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 133.16  E-value: 1.68e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDDLVTVEEHL 2355
Cdd:pfam00005    1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENL 80
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2356 YFYARVHGIPEKDIKETVHKLLRRLHLMPFKDR----ATSMCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:pfam00005   81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
1338-1572 6.26e-28

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 123.70  E-value: 6.26e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1338 IEPEPKDLTVGVAL--HGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTD 1415
Cdd:NF033858   254 IPPRPADDDDEPAIeaRGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAG 333
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1416 LHTVRKNMGVCMQHDVLFSYLTTKEHLLLYGsiKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIA 1495
Cdd:NF033858   334 DIATRRRVGYMSQAFSLYGELTVRQNLELHA--RLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVA 411
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1496 LIGGSRVVILDEPSTGVDPCSRRSIWDVISknKTAR----TIILSTHHLDEAEvLSDRIAFLEQGGLRCCGSPFYLKEAF 1571
Cdd:NF033858   412 VIHKPELLILDEPTSGVDPVARDMFWRLLI--ELSRedgvTIFISTHFMNEAE-RCDRISLMHAGRVLASDTPAALVAAR 488

                   .
gi 2462571778 1572 G 1572
Cdd:NF033858   489 G 489
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
2275-2469 9.69e-26

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 116.76  E-value: 9.69e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrnktgsLGH-VDSHS----SLVGYCPQEDALDDLV 2349
Cdd:NF033858   281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWL------FGQpVDAGDiatrRRVGYMSQAFSLYGEL 354
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2350 TVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKR 2429
Cdd:NF033858   355 TVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARD 434
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 2462571778 2430 HLWKIISE-EVQNKCSVILTSHSMEECEaLCTRLAIMVNGK 2469
Cdd:NF033858   435 MFWRLLIElSREDGVTIFISTHFMNEAE-RCDRISLMHAGR 474
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
1349-1544 1.83e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 109.06  E-value: 1.83e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVR-------- 1420
Cdd:NF033858     2 ARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRRAvcpriaym 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1421 -----KNmgvcmqhdvLFSYLTTKEHLL----LYGsikvpHwTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLS 1491
Cdd:NF033858    82 pqglgKN---------LYPTLSVFENLDffgrLFG-----Q-DAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLG 146
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 1492 ISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTAR---TIILSTHHLDEAE 1544
Cdd:NF033858   147 LCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERpgmSVLVATAYMEEAE 202
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
2272-2491 8.00e-21

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 96.73  E-value: 8.00e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2272 KIIAVNNISIGIPAGECFGLLGVNGAG--KTTIFKMLTGdiiPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDDLV 2349
Cdd:NF000106    25 EVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGRRPWRF*TWCANRRALRRTIG*HRPVR*GRRESF 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2350 TVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKR 2429
Cdd:NF000106   102 SGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRN 181
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2430 HLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKSRFGrGFTVKV 2491
Cdd:NF000106   182 EVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG-GRTLQI 242
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
1358-1543 2.47e-16

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 79.59  E-value: 2.47e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI------KTDLH-----TVRK--NMG 1424
Cdd:NF040873     2 YGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARvayvpqRSEVPdslplTVRDlvAMG 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1425 VcMQHDVLFSYLTTKEHLllygsikvphwtkkqlheEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:NF040873    82 R-WARRGLWRRLTRDDRA------------------AVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLL 142
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEA 1543
Cdd:NF040873   143 LDEPTTGLDAESRERIIALLAEeHARGATVVVVTHDLELV 182
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
1348-1572 5.68e-16

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 82.09  E-value: 5.68e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1348 GVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTiSMLTGLFGASAGT----IFVYGKDIKTDLHTVRKNM 1423
Cdd:NF000106    13 AVEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRrpwrF*TWCANRRALRRTIG*HR 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1424 GVCMQHDVLFSyltTKEHLLLYGsiKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVV 1503
Cdd:NF000106    92 PVR*GRRESFS---GRENLYMIG--R*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVL 166
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1504 ILDEPSTGVDPCSRRSIWD-VISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFG 1572
Cdd:NF000106   167 YLDEPTTGLDPRTRNEVWDeVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG 236
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
2272-2484 1.71e-15

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 83.25  E-value: 1.71e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2272 KIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIL-----IRNKtgslGHVDSHSSLVGYCPQedALD 2346
Cdd:NF033858    13 KTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEvlggdMADA----RHRRAVCPRIAYMPQ--GLG 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2347 -----DLvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:NF033858    87 knlypTL-SVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTT 165
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2422 GMDPKSKRHLWKIISE--EVQNKCSVILTSHSMEECEAlCTRLAIMVNGKFQCIGSLQHIKSRFG 2484
Cdd:NF033858   166 GVDPLSRRQFWELIDRirAERPGMSVLVATAYMEEAER-FDWLVAMDAGRVLATGTPAELLARTG 229
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
7-86 1.00e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 71.20  E-value: 1.00e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778    7 QLQILVWKNWLGVKRQPLWTLVLILWPVIIFIILAITRTKFPPTAKPTCYLAPRNLPSTGFFPFLQTLLCDTDSKCKDTP 86
Cdd:TIGR01257    6 QIQLLLWKNWTLRKRQKIRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCFQSP 85
GguA NF040905
sugar ABC transporter ATP-binding protein;
1353-1556 3.64e-06

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 52.10  E-value: 3.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGL--FGASAGTIFVYG-----KDIKTDLHtvrknMGV 1425
Cdd:NF040905     6 GITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVypHGSYEGEILFDGevcrfKDIRDSEA-----LGI 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1426 CMQHD--VLFSYLTTKEHLLL------YGSIkvpHWtkKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALI 1497
Cdd:NF040905    81 VIIHQelALIPYLSIAENIFLgnerakRGVI---DW--NETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALS 155
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1498 GGSRVVILDEPSTGVDPCSRRSIWDVIS--KNKTARTIILStHHLDEAEVLSDRIAFLEQG 1556
Cdd:NF040905   156 KDVKLLILDEPTAALNEEDSAALLDLLLelKAQGITSIIIS-HKLNEIRRVADSITVLRDG 215
 
Name Accession Description Interval E-value
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
752-2579 0e+00

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 1233.73  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  752 NHTKDFLTYKLTKEQIAskYGIPINTTPFCFSLYKDIINMPAGPVIWAFLKPMLLGRILYAPYNPVTKAIMEKSNVTLRQ 831
Cdd:TIGR01257  343 NNYKAFLGIDSTRKDPI--YSYDKRTTSFCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARRILKNANSTFEE 420
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  832 LAELREKSQEWMDKSPLFMNSFHLLNQaIPMLQNTLRNPFVQVFVKFSVGLDAV--ELL----------KQIDELDILRL 899
Cdd:TIGR01257  421 LERVRKLVKAWEEVGPQIWYFFDKSTQ-MTMIRDTLQNPTVKDFINRQLGEEGItaEAVlnflyngpreKQADDMTNFDW 499
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  900 KlenniDIIDQLNTLSSLTVNISSCVLYDRIQAAKTIDEMEREAKRLYKSNELFGSVIFklPSNRSWHRGydsgnvfLPP 979
Cdd:TIGR01257  500 R-----DIFNITDRFLRLANQYLECLVLDKFESYDDEVQLTQRALSLLEENRFWAGVVF--PDMYPWTSS-------LPP 565
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778  980 VIKYTIRMSLKTAQTTRSLRTKIWAPGPHNSPSHN--QIYGrAFIYLQDSIERAIIELQTgRNSQEIAVQVQAIPYPCFM 1057
Cdd:TIGR01257  566 HVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDfrYIWG-GFAYLQDMVEQGITRSQM-QAEPPVGIYLQQMPYPCFV 643
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1058 KDNFLTSVSYSLPIVLMVAWVVFIAAFVKKLVYEKDLRLHEYMKMMGVNSCSHFFAWLIESVGFLLVTIVILIIILKFGN 1137
Cdd:TIGR01257  644 DDSFMIILNRCFPIFMVLAWIYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR 723
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1138 ILPKTNGFILFLYFSDYSFSVIAMSYLISVFFNNTNIAALIGSLIYIIAFFPFIVLVTVENELSYVLKVFMSLLSPTAFS 1217
Cdd:TIGR01257  724 ILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQDRMTADLKTAVSLLSPVAFG 803
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1218 YASQYIARYEEQGIGLQWENMYTSPVQDDTTSFGWLCCLILADSFIYFLIAWYVRNVFPGTYGMAAPWYFPILPSYWKER 1297
Cdd:TIGR01257  804 FGTEYLVRFEEQGLGLQWSNIGNSPLEGDEFSFLLSMKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGG 883
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1298 FGCAeVKPEKSnglmftnimMQNTNPSASKTS----PEYMFSSNIEPEPKDLTVGVALHGVTKIY--GSKVAVDNLNLNF 1371
Cdd:TIGR01257  884 EGCS-TREERA---------LEKTEPLTEEMEdpehPEGINDSFFERELPGLVPGVCVKNLVKIFepSGRPAVDRLNITF 953
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1372 YEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVP 1451
Cdd:TIGR01257  954 YENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGR 1033
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1452 HWTKKQLheEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTAR 1531
Cdd:TIGR01257 1034 SWEEAQL--EMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGR 1111
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1532 TIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFGDGYHLTLTKK----KSPNLNANAVC-------------- 1593
Cdd:TIGR01257 1112 TIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKmkniQSQRGGCEGTCsctskgfstrcpar 1191
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1594 ------------DTMAVTAMIQSHLPEAYLKEDIGGELVYVLPPFSTKvSGAYLSLLRALDNGMGDLNIGCYGISDTTVE 1661
Cdd:TIGR01257 1192 vdeitpeqvldgDVNELMDLVYHHVPEAKLVECIGQELIFLLPNKNFK-QRAYASLFRELEETLADLGLSSFGISDTPLE 1270
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1662 EVFLNLTKES-----------QKNSAMSLEH----LTQKKIGNSNANGISTPDDLSVSSSN--FTDRDDKiltrGERLD- 1723
Cdd:TIGR01257 1271 EIFLKVTEDAdsgslfaggaqQKRENANLRHpcsgPTEKAGQTPQASHTCSPGQPAAHPEGqpPPEPEDP----GVPLNt 1346
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1724 GFGLLLKKIMAILIKRFHHTRRNWKGLIAQVILPIVFVTTAMGLGTLRNSSNSYPEIQISPSLYGtsEQTAFYANYHPST 1803
Cdd:TIGR01257 1347 GARLILQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPALTLHPWMYG--QQYTFFSMDEPNS 1424
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1804 E---ALVSAMWDFPGIDNMCLNTS---DLQCLNKDSL---------------EKWnTSGEPITNfgvCSCSEN-----VQ 1857
Cdd:TIGR01257 1425 EhleVLADVLLNKPGFGNRCLKEEwlpEYPCGNSTPWktpsvspnithlfqkQKW-TAAHPSPS---CRCSTRekltmLP 1500
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1858 ECPK--FNYSPPHRRTYSSQVIYNLTGQRVENYLISTANEFV-----------QKRYGGWSFG-----LPLT-------- 1911
Cdd:TIGR01257 1501 ECPEgaGGLPPPQRTQRSTEILQDLTDRNISDFLVKTYPALIrsslkskfwvnEQRYGGISIGgklpaIPITgealvgfl 1580
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1912 KDL--RFDITGVPANRTLA----------------KVWYDPEGYHSLPAYLNSLNNFLLRVNMSK-YDAARHGIIMYSHP 1972
Cdd:TIGR01257 1581 SDLgqMMNVSGGPVTREASkempdflkhletedniKVWFNNKGWHALVSFLNVAHNAILRASLPKdRDPEEYGITVISQP 1660
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1973 YPGVQDQ--EQATISSLIDILVALSILMGYSVTTASFVTYVVREHQTKAKQLQHISGIGVTCYWVTNFIYDMVFYLVPVA 2050
Cdd:TIGR01257 1661 LNLTKEQlsEITVLTTSVDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFISGVSPTTYWLTNFLWDIMNYAVSAG 1740
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2051 FSIGIIAIFKLPAFYSENNLGAVSLLLLLFGYATFSWMYLLAGLFHETGMAFITYVCVNLFFGINSivslSVVYFLSKEK 2130
Cdd:TIGR01257 1741 LVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINS----SAITFVLELF 1816
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2131 PNDPTLELISETLKRIFLIFPQFCFGYGLIELSQQQSVLDFLKAYGVEYPNETFEMNKLGAMFVALVSQGTMFFSLRLLI 2210
Cdd:TIGR01257 1817 ENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDVYAQFGEEHSANPFQWDLIGKNLVAMAVEGVVYFLLTLLI 1896
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2211 NEslikklRLFFRKFNSSHVRETI-DEDEDVRAERLRVESGAAEFDLVQLYCLTKTYQLIHKKiiAVNNISIGIPAGECF 2289
Cdd:TIGR01257 1897 QH------HFFLSRWIAEPAKEPIfDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGTSSP--AVDRLCVGVRPGECF 1968
                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2290 GLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLvGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDI 2369
Cdd:TIGR01257 1969 GLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVHQNM-GYCPQFDAIDDLLTGREHLYLYARLRGVPAEEI 2047
                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2370 KETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTS 2449
Cdd:TIGR01257 2048 EKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTS 2127
                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2450 HSMEECEALCTRLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNK----VTMETLTKFMQLHFPKTYLKDQHLSMLE 2525
Cdd:TIGR01257 2128 HSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSPKddllPDLNPVEQFFQGNFPGSVQRERHYNMLQ 2207
                         1930      1940      1950      1960      1970
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 2526 YHVPVTAggVANIFDLLETNKTALNITNFLVSQTTLEEVFINFAKDQKsyETAD 2579
Cdd:TIGR01257 2208 FQVSSSS--LARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQT--ETYD 2257
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
2257-2480 6.87e-98

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 314.83  E-value: 6.87e-98
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2257 VQLYCLTKTYqliHKKI-IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrNKTGSLGHVDSHSSL 2335
Cdd:cd03263      1 LQIRNLTKTY---KKGTkPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYI-NGYSIRTDRKAARQS 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2336 VGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILL 2415
Cdd:cd03263     77 LGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLL 156
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2416 LDEPSSGMDPKSKRHLWKIISEEVQNKcSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIK 2480
Cdd:cd03263    157 LDEPTSGLDPASRRAIWDLILEVRKGR-SIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
1353-1568 1.45e-97

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 313.67  E-value: 1.45e-97
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIYGS--KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHD 1430
Cdd:cd03263      5 NLTKTYKKgtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQSLGYCPQFD 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSYLTTKEHLLLYGSIK-VPHWTKKqlhEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPS 1509
Cdd:cd03263     85 ALFDELTVREHLRFYARLKgLPKSEIK---EEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPT 161
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1510 TGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLK 1568
Cdd:cd03263    162 SGLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
1349-1584 1.47e-78

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 260.00  E-value: 1.47e-78
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQ 1428
Cdd:COG1131      1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRRIGYVPQ 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHLLLYGSIK-VPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDE 1507
Cdd:COG1131     81 EPALYPDLTVRENLRFFARLYgLP---RKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDE 157
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1508 PSTGVDPCSRRSIWDVISKNKTA-RTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFGDGYHLTLTKKKS 1584
Cdd:COG1131    158 PTSGLDPEARRELWELLRELAAEgKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARLLEDVFLELTGEEA 235
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
2262-2483 4.41e-73

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 244.20  E-value: 4.41e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrnktgsLGH-VDSHS----SLV 2336
Cdd:COG1131      6 LTKRY----GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRV------LGEdVARDPaevrRRI 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2337 GYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLL 2416
Cdd:COG1131     76 GYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLIL 155
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 2417 DEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKSRF 2483
Cdd:COG1131    156 DEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARL 222
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
1349-1558 8.31e-62

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 209.56  E-value: 8.31e-62
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQ 1428
Cdd:cd03230      1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVKRRIGYLPE 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHLllygsikvphwtkkqlheevkrtlkdtglyshrhkrvgTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:cd03230     81 EPSLYENLTVRENL--------------------------------------KLSGGMKQRLALAQALLHDPELLILDEP 122
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1509 STGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGL 1558
Cdd:cd03230    123 TSGLDPESRREFWELLRElKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
1356-1573 1.56e-58

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 205.32  E-value: 1.56e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1356 KIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSY 1435
Cdd:TIGR01188    1 KVYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVVREPRKVRRSIGIVPQYASVDED 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 LTTKEHLLLYGSIK-VPHWTKKQLHEEVkrtLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDP 1514
Cdd:TIGR01188   81 LTGRENLEMMGRLYgLPKDEAEERAEEL---LELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDP 157
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1515 CSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFGD 1573
Cdd:TIGR01188  158 RTRRAIWDYIRAlKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLGK 217
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
1353-1568 2.76e-58

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 201.44  E-value: 2.76e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVL 1432
Cdd:cd03265      5 NLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREVRRRIGIVFQDLSV 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1433 FSYLTTKEHLLLYGSIK-VPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTG 1511
Cdd:cd03265     85 DDELTGWENLYIHARLYgVP---GAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIG 161
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1512 VDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLK 1568
Cdd:cd03265    162 LDPQTRAHVWEYIEKlkEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
1351-1573 5.30e-56

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 195.46  E-value: 5.30e-56
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHD 1430
Cdd:COG4555      4 VENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREARRQIGVLPDER 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSYLTTKEHLLLYGSIKvpHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:COG4555     84 GLYDRLTVRENIRYFAELY--GLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTN 161
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1511 GVDPCSRRSIWDVISKNKTA-RTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFGD 1573
Cdd:COG4555    162 GLDVMARRLLREILRALKKEgKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGE 225
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
2262-2485 4.51e-55

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 192.77  E-value: 4.51e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtGSLGHVDSHSSLVGYCPQ 2341
Cdd:COG4555      7 LSKKY----GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGE-DVRKEPREARRQIGVLPD 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:COG4555     82 ERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTN 161
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 2422 GMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKSRFGR 2485
Cdd:COG4555    162 GLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGE 225
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
2262-2470 7.74e-55

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 189.53  E-value: 7.74e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrNKTGSLGHVDSHSSLVGYCPQ 2341
Cdd:cd03230      6 LSKRY----GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKV-LGKDIKKEPEEVKRRIGYLPE 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLVTVEEHLYFyarvhgipekdiketvhkllrrlhlmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:cd03230     81 EPSLYENLTVRENLKL------------------------------------SGGMKQRLALAQALLHDPELLILDEPTS 124
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 2422 GMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKF 2470
Cdd:cd03230    125 GLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
1351-1679 3.50e-51

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 201.40  E-value: 3.50e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYG--SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQ 1428
Cdd:TIGR01257 1940 LNELTKVYSgtSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVHQNMGYCPQ 2019
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHLLLYGSIK-VPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDE 1507
Cdd:TIGR01257 2020 FDAIDDLLTGREHLYLYARLRgVP---AEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDE 2096
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1508 PSTGVDPCSRRSIWDVI-SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFGDGYHLTLtKKKSPN 1586
Cdd:TIGR01257 2097 PTTGMDPQARRMLWNTIvSIIREGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTM-KIKSPK 2175
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1587 lnANAVCDTMAVTAMIQSHLPEAYLKEDIGGELVYVLPpfstkvSGAYLSLLRALDNGMGDLNIGCYGISDTTVEEVFLN 1666
Cdd:TIGR01257 2176 --DDLLPDLNPVEQFFQGNFPGSVQRERHYNMLQFQVS------SSSLARIFQLLISHKDSLLIEEYSVTQTTLDQVFVN 2247
                          330
                   ....*....|...
gi 2462571778 1667 LTKESQKNSAMSL 1679
Cdd:TIGR01257 2248 FAKQQTETYDLPL 2260
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
1349-1562 1.24e-50

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 178.93  E-value: 1.24e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGhITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQ 1428
Cdd:cd03264      1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRRIGYLPQ 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHL----LLYGsikVPHwtkKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:cd03264     80 EFGVYPNFTVREFLdyiaWLKG---IPS---KEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILI 153
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCG 1562
Cdd:cd03264    154 VDEPTAGLDPEERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
2275-2480 2.91e-50

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 178.33  E-value: 2.91e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNilirnktgslGHVDSHSSL---------VGYCPQEDAL 2345
Cdd:cd03265     15 AVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGR----------ATVAGHDVVreprevrrrIGIVFQDLSV 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2346 DDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDP 2425
Cdd:cd03265     85 DDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDP 164
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 2426 KSKRHLWKIISEEVQ-NKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIK 2480
Cdd:cd03265    165 QTRAHVWEYIEKLKEeFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
2262-2572 6.26e-49

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 177.22  E-value: 6.26e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDshssLVGYCPQ 2341
Cdd:COG4152      7 LTKRF----GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPEDRR----RIGYLPE 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:COG4152     79 ERGLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFS 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2422 GMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK--FQciGSLQHIKSRFGRGfTVKVHLKNNKVT 2499
Cdd:COG4152    159 GLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRkvLS--GSVDEIRRQFGRN-TLRLEADGDAGW 235
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 2500 METLTKfmqlhfpktyLKDQHLSMLEYHVPVTAGGVANifDLLETNKTALNITNFLVSQTTLEEVFINFAKDQ 2572
Cdd:COG4152    236 LRALPG----------VTVVEEDGDGAELKLEDGADAQ--ELLRALLARGPVREFEEVRPSLNEIFIEVVGEK 296
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
1353-1559 1.11e-48

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 173.17  E-value: 1.11e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGVCMQHDVL 1432
Cdd:cd03268      5 DLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSY-QKNIEALRRIGALIEAPGF 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1433 FSYLTTKEHLLLYGSIkvphwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGV 1512
Cdd:cd03268     84 YPNLTARENLRLLARL------LGIRKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGL 157
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 1513 DPCSRRSIWDVI-SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLR 1559
Cdd:cd03268    158 DPDGIKELRELIlSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
2257-2471 2.45e-47

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 169.30  E-value: 2.45e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2257 VQLYCLTKTYqlihKKIIAVNNISIGIPAGeCFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrNKTGSLGHVDSHSSLV 2336
Cdd:cd03264      1 LQLENLTKRY----GKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRI-DGQDVLKQPQKLRRRI 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2337 GYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLL 2416
Cdd:cd03264     75 GYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIV 154
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2417 DEPSSGMDPKSK---RHLwkiISEEVQNKCsVILTSHSMEECEALCTRLAIMVNGKFQ 2471
Cdd:cd03264    155 DEPTAGLDPEERirfRNL---LSELGEDRI-VILSTHIVEDVESLCNQVAVLNKGKLV 208
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
1349-1577 4.23e-47

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 169.44  E-value: 4.23e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIY-GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-KTDLHTVRKNMGVC 1426
Cdd:COG1122      1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDItKKNLRELRRKVGLV 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 MQH------------DVLFSylttkehLLLYGsikvphWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISI 1494
Cdd:COG1122     81 FQNpddqlfaptveeDVAFG-------PENLG------LPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAG 147
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1495 ALIGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPfylKEAFGD 1573
Cdd:COG1122    148 VLAMEPEVLVLDEPTAGLDPRGRRELLELLKRlNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTP---REVFSD 224

                   ....
gi 2462571778 1574 GYHL 1577
Cdd:COG1122    225 YELL 228
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
1351-1556 3.83e-45

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 163.02  E-value: 3.83e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGS--KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-KTDLHTVRKNMGVCM 1427
Cdd:cd03225      2 LKNLSFSYPDgaRPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLtKLSLKELRRKVGLVF 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QH-DVLFSYLTTKE----HLLLYGsikvphWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRV 1502
Cdd:cd03225     82 QNpDDQFFGPTVEEevafGLENLG------LPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDI 155
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1503 VILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03225    156 LLLDEPTAGLDPAGRRELLELLKKlKAEGKTIIIVTHDLDLLLELADRVIVLEDG 210
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
2262-2469 2.58e-44

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 160.91  E-value: 2.58e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgslGHVDSHSSLVGYCPQ 2341
Cdd:cd03269      6 VTKRF----GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGK----PLDIAARNRIGYLPE 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:cd03269     78 ERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFS 157
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 2422 GMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03269    158 GLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGR 205
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1351-1572 2.66e-44

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 163.74  E-value: 2.66e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKtdlHTVRKNMGvcmqhd 1430
Cdd:COG4152      4 LKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLD---PEDRRRIG------ 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 vlfsYL----------TTKEHLLLYGSIKvpHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGS 1500
Cdd:COG4152     75 ----YLpeerglypkmKVGEQLVYLARLK--GLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDP 148
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1501 RVVILDEPSTGVDPCSRRSIWDVI-SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFG 1572
Cdd:COG4152    149 ELLILDEPFSGLDPVNVELLKDVIrELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFG 221
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
2275-2479 8.53e-44

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 159.81  E-value: 8.53e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQeDALDDLV--TVE 2352
Cdd:COG1122     16 ALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRKVGLVFQ-NPDDQLFapTVE 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2353 EHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLW 2432
Cdd:COG1122     95 EDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELL 174
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2462571778 2433 KIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:COG1122    175 ELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREV 221
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
2257-2469 2.50e-43

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 157.76  E-value: 2.50e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2257 VQLYCLTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSHSSLV 2336
Cdd:cd03268      1 LKTNDLTKTY----GKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGK--SYQKNIEALRRI 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2337 GYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETvhklLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLL 2416
Cdd:cd03268     75 GALIEAPGFYPNLTARENLRLLARLLGIRKKRIDEV----LDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLIL 150
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 2417 DEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03268    151 DEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGK 203
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
1351-1556 4.53e-43

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 157.30  E-value: 4.53e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGVCMQHD 1430
Cdd:cd03259      3 LKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDV-TGVPPERRNIGMVFQDY 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSYLTTKEHlLLYGsIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:cd03259     82 ALFPHLTVAEN-IAFG-LKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLS 159
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 1511 GVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03259    160 ALDAKLREELREELKElqRELGITTIYVTHDQEEALALADRIAVMNEG 207
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
2262-2469 1.79e-42

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 155.32  E-value: 1.79e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQliHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQ 2341
Cdd:cd03225      5 LSFSYP--DGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKVGLVFQ 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 eDALDDLV--TVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEP 2419
Cdd:cd03225     83 -NPDDQFFgpTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEP 161
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2420 SSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03225    162 TAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
2256-2469 3.28e-42

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 155.22  E-value: 3.28e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2256 LVQLYCLTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNktgslghVDSHSS- 2334
Cdd:cd03266      1 MITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDG-------FDVVKEp 73
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2335 -----LVGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIG 2409
Cdd:cd03266     74 aearrRLGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVH 153
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2410 KPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03266    154 DPPVLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGR 213
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
1346-1567 4.45e-42

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 158.84  E-value: 4.45e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1346 TVGVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGV 1425
Cdd:PRK13536    39 TVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLARARIGV 118
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1426 CMQHDVLFSYLTTKEHLLLYGsiKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVIL 1505
Cdd:PRK13536   119 VPQFDNLDLEFTVRENLLVFG--RYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLIL 196
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1506 DEPSTGVDPCSRRSIWDVI-SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYL 1567
Cdd:PRK13536   197 DEPTTGLDPHARHLIWERLrSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHAL 259
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
1349-1570 1.04e-41

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 156.89  E-value: 1.04e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQ 1428
Cdd:PRK13537     8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQRVGVVPQ 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHLLLYGsiKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:PRK13537    88 FDNLDPDFTVRENLLVFG--RYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEP 165
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1509 STGVDPCSRRSIWDVI-SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEA 1570
Cdd:PRK13537   166 TTGLDPQARHLMWERLrSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIES 228
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
1349-1577 2.35e-41

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 153.71  E-value: 2.35e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVrknmG-VCM 1427
Cdd:COG1121      7 IELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRRI----GyVPQ 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QHDVLFSY-LTTKEHLL--LYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:COG1121     83 RAEVDWDFpITVRDVVLmgRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLLL 162
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEqGGLRCCGSP------FYLKEAFGDGYHL 1577
Cdd:COG1121    163 LDEPFAGVDAATEEALYELLRElRREGKTILVVTHDLGAVREYFDRVLLLN-RGLVAHGPPeevltpENLSRAYGGPVAL 241
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
1349-1564 3.87e-41

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 152.83  E-value: 3.87e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT----DLHTVRKNMG 1424
Cdd:COG1127      6 IEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGlsekELYELRRRIG 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1425 VCMQHDVLFSYLTT--------KEHLLLygsikvphwTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIAL 1496
Cdd:COG1127     86 MLFQGGALFDSLTVfenvafplREHTDL---------SEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARAL 156
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1497 IGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTAR--TIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:COG1127    157 ALDPEILLYDEPTAGLDPITSAVIDELIRELRDELglTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTP 226
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
1349-1556 4.80e-41

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 151.28  E-value: 4.80e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDlhtVRKNMGVCMQ 1428
Cdd:cd03269      1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIA---ARNRIGYLPE 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHLLLYGSIKvpHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:cd03269     78 ERGLYPKMKVIDQLVYLAQLK--GLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEP 155
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 1509 STGVDPCSRRSIWDVISKNKTA-RTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03269    156 FSGLDPVNVELLKDVIRELARAgKTVILSTHQMELVEELCDRVLLLNKG 204
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
2262-2509 6.60e-40

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 152.16  E-value: 6.60e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQlIHKK------------------IIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRnkt 2323
Cdd:COG4586      7 LSKTYR-VYEKepglkgalkglfrreyreVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVL--- 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2324 gslghvdshsslvGYCPQEDALD-----------------DLvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFK 2386
Cdd:COG4586     83 -------------GYVPFKRRKEfarrigvvfgqrsqlwwDL-PAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELL 148
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2387 DRATsmcsygtkRKLS--------TALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQ-NKCSVILTSHSMEECEA 2457
Cdd:COG4586    149 DTPV--------RQLSlgqrmrceLAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNReRGTTILLTSHDMDDIEA 220
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2458 LCTRLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNkVTMETLTKFMQL 2509
Cdd:COG4586    221 LCDRVIVIDHGRIIYDGSLEELKERFGPYKTIVLELAEP-VPPLELPRGGEV 271
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
2278-2450 7.51e-40

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 147.63  E-value: 7.51e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLgHVDSHSSLVGYCPQEDALDDLVTVEEHLYF 2357
Cdd:COG4133     20 GLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRD-AREDYRRRLAYLGHADGLKPELTVRENLRF 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2358 YARVHGIPEKDikETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISE 2437
Cdd:COG4133     99 WAALYGLRADR--EAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAA 176
                          170
                   ....*....|...
gi 2462571778 2438 EVQNKCSVILTSH 2450
Cdd:COG4133    177 HLARGGAVLLTTH 189
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
1353-1564 1.09e-39

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 148.35  E-value: 1.09e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCM--QHD 1430
Cdd:cd03219      5 GLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARLGIGRtfQIP 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSYLTTKEHLLLYGSIKVPHWT--------KKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRV 1502
Cdd:cd03219     85 RLFPELTVLENVMVAAQARTGSGLllararreEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKL 164
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1503 VILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:cd03219    165 LLLDEPAAGLNPEETEELAELIRElRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTP 227
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
1349-1559 2.00e-39

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 147.13  E-value: 2.00e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSK----VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMG 1424
Cdd:cd03266      2 ITADALTKRFRDVkktvQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEARRRLG 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1425 VCMQHDVLFSYLTTKEHLLLYGSIkvpHWTKK-QLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVV 1503
Cdd:cd03266     82 FVSDSTGLYDRLTARENLEYFAGL---YGLKGdELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVL 158
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1504 ILDEPSTGVDPCSRRSIWDVISKNKTA-RTIILSTHHLDEAEVLSDRIAFLEQGGLR 1559
Cdd:cd03266    159 LLDEPTTGLDVMATRALREFIRQLRALgKCILFSTHIMQEVERLCDRVVVLHRGRVV 215
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
1349-1553 6.25e-39

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 145.69  E-value: 6.25e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSK----VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKtdlhTVRKNMG 1424
Cdd:cd03293      1 LEVRNVSKTYGGGggavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVT----GPGPDRG 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1425 VCMQHDVLFSYLTTKEHLLLygSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:cd03293     77 YVFQQDALLPWLTVLDNVAL--GLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLL 154
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFL 1553
Cdd:cd03293    155 LDEPFSALDALTREQLQEELLDiwRETGKTVLLVTHDIDEAVFLADRVVVL 205
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
1351-1544 1.27e-38

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 144.16  E-value: 1.27e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHD 1430
Cdd:COG4133      5 AENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDYRRRLAYLGHAD 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSYLTTKEHLLLYGSIKVPHWTkkqlHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:COG4133     85 GLKPELTVRENLRFWAALYGLRAD----REAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFT 160
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2462571778 1511 GVDPCSRRSIWDVISKNKTA-RTIILSTHHLDEAE 1544
Cdd:COG4133    161 ALDAAGVALLAELIAAHLARgGAVLLTTHQPLELA 195
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
2257-2469 2.32e-38

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 148.06  E-value: 2.32e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2257 VQLYCLTKTYQlihKKIIaVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrnktgsLG-HVDSHSSL 2335
Cdd:PRK13536    42 IDLAGVSKSYG---DKAV-VNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITV------LGvPVPARARL 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2336 ----VGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKP 2411
Cdd:PRK13536   112 ararIGVVPQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDP 191
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2412 SILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK13536   192 QLLILDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGR 249
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
1351-1564 2.37e-38

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 145.18  E-value: 2.37e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHT---VRKNMGVCM 1427
Cdd:COG0411      7 VRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDI-TGLPPhriARLGIARTF 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QHDVLFSYLTTKEHLLL-----------YGSIKVPHWTK--KQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISI 1494
Cdd:COG0411     86 QNPRLFPELTVLENVLVaaharlgrgllAALLRLPRARReeREARERAEELLERVGLADRADEPAGNLSYGQQRRLEIAR 165
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1495 ALIGGSRVVILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:COG0411    166 ALATEPKLLLLDEPAAGLNPEETEELAELIRRlrDERGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTP 237
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
1351-1564 3.07e-38

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 144.18  E-value: 3.07e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI----KTDLHTVRKNMGVC 1426
Cdd:cd03261      3 LRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDIsglsEAELYRLRRRMGML 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 MQHDVLFSYLTT--------KEHLLLygsikvphwTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIG 1498
Cdd:cd03261     83 FQSGALFDSLTVfenvafplREHTRL---------SEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALAL 153
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1499 GSRVVILDEPSTGVDPCSRRSIWDVIS--KNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:cd03261    154 DPELLLYDEPTAGLDPIASGVIDDLIRslKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTP 221
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
1349-1564 1.71e-37

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 141.99  E-value: 1.71e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGVCMQ 1428
Cdd:cd03300      1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDI-TNLPPHKRPVNTVFQ 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHlLLYGsIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:cd03300     80 NYALFPHLTVFEN-IAFG-LRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEP 157
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1509 STGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:cd03300    158 LGALDLKLRKDMQLELKRlqKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTP 215
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
2274-2469 2.15e-37

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 144.18  E-value: 2.15e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSlGHVDSHSSLVGYCPQEDALDDLVTVEE 2353
Cdd:PRK13537    21 LVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVP-SRARHARQRVGVVPQFDNLDPDFTVRE 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 HLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWK 2433
Cdd:PRK13537   100 NLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWE 179
                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 2462571778 2434 IISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK13537   180 RLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGR 215
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
1351-1556 3.36e-37

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 138.15  E-value: 3.36e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-KTDLHTVRKNMGVCMQh 1429
Cdd:cd00267      2 IENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIaKLPLEELRRRIGYVPQ- 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 dvlfsylttkehlllygsikvphwtkkqlheevkrtlkdtglyshrhkrvgtLSGGMKRKLSISIALIGGSRVVILDEPS 1509
Cdd:cd00267     81 ----------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPT 108
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 1510 TGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd00267    109 SGLDPASRERLLELLRElAEEGRTVIIVTHDPELAELAADRVIVLKDG 156
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
1349-1564 4.47e-37

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 141.28  E-value: 4.47e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIY-GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIK-TDLHTVRKNMGVC 1426
Cdd:cd03295      1 IEFENVTKRYgGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIReQDPVELRRKIGYV 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 MQHDVLFSYLTTKEHLLLygsikVP---HWTKKQLHEEVKRTLKDTGL----YSHRHKRvgTLSGGMKRKLSISIALIGG 1499
Cdd:cd03295     81 IQQIGLFPHMTVEENIAL-----VPkllKWPKEKIRERADELLALVGLdpaeFADRYPH--ELSGGQQQRVGVARALAAD 153
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1500 SRVVILDEPSTGVDPCSRRSIWDVISKNKTA--RTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:cd03295    154 PPLLLMDEPFGALDPITRDQLQEEFKRLQQElgKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTP 220
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
1349-1564 7.88e-37

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 140.95  E-value: 7.88e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCM 1427
Cdd:COG1120      2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASlSRRELARRIAYVP 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QHDVLFSYLTTKEhLLLYGsiKVPH-----WTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRV 1502
Cdd:COG1120     82 QEPPAPFGLTVRE-LVALG--RYPHlglfgRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPL 158
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1503 VILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:COG1120    159 LLLDEPTSHLDLAHQLEVLELLRRlaRERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPP 222
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
1343-1556 3.30e-36

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 137.66  E-value: 3.30e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1343 KDLTVGvalhgvtkiYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDlhtvRKN 1422
Cdd:cd03235      3 EDLTVS---------YGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKE----RKR 69
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1423 MG-VCMQHDVLFSY-LTTKEHLL--LYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIG 1498
Cdd:cd03235     70 IGyVPQRRSIDRDFpISVRDVVLmgLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQ 149
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1499 GSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03235    150 DPDLLLLDEPFAGVDPKTQEDIYELLRElRREGMTILVVTHDLGLVLEYFDRVLLLNRT 208
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
2262-2469 5.40e-36

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 137.67  E-value: 5.40e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSL-VGYCP 2340
Cdd:cd03218      6 LSKRY----GKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLgIGYLP 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2341 QEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPS 2420
Cdd:cd03218     82 QEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEPF 161
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 2421 SGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03218    162 AGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGK 210
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
2262-2474 7.56e-36

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 136.50  E-value: 7.56e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQlihkKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgsLGHVDSHSSLVGYCPQ 2341
Cdd:cd03259      6 LSKTYG----SVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRD--VTGVPPERRNIGMVFQ 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:cd03259     80 DYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLS 159
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 2422 GMDPKSKRHLWKIISE-EVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIG 2474
Cdd:cd03259    160 ALDAKLREELREELKElQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
1349-1553 9.54e-36

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 137.91  E-value: 9.54e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIY----GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIktdlHTVRKNMG 1424
Cdd:COG1116      8 LELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPV----TGPGPDRG 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1425 VCMQHDVLFSYLTTKEHLLLygSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:COG1116     84 VVFQEPALLPWLTVLDNVAL--GLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLL 161
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFL 1553
Cdd:COG1116    162 MDEPFGALDALTRERLQDELLRlwQETGKTVLFVTHDVDEAVFLADRVVVL 212
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
2276-2421 1.68e-35

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 133.16  E-value: 1.68e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDDLVTVEEHL 2355
Cdd:pfam00005    1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENL 80
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2356 YFYARVHGIPEKDIKETVHKLLRRLHLMPFKDR----ATSMCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:pfam00005   81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
1351-1556 4.23e-35

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 133.08  E-value: 4.23e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTV---RKNMGVCM 1427
Cdd:cd03229      3 LKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELpplRRRIGMVF 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QHDVLFSYLTTKEHLLLygsikvphwtkkqlheevkrtlkdtglyshrhkrvgTLSGGMKRKLSISIALIGGSRVVILDE 1507
Cdd:cd03229     83 QDFALFPHLTVLENIAL------------------------------------GLSGGQQQRVALARALAMDPDVLLLDE 126
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1508 PSTGVDPCSRRSIWDVISKNKT--ARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03229    127 PTSALDPITRREVRALLKSLQAqlGITVVLVTHDLDEAARLADRVVVLRDG 177
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
2262-2469 6.32e-35

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 131.98  E-value: 6.32e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQ 2341
Cdd:cd00267      5 LSFRY----GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRIGYVPQ 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 edalddlvtveehlyfyarvhgipekdiketvhkllrrlhlmpfkdratsmCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:cd00267     81 ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTS 109
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 2422 GMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd00267    110 GLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
1364-1510 1.91e-34

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 130.08  E-value: 1.91e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1364 VDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-KTDLHTVRKNMGVCMQHDVLFSYLTTKEHL 1442
Cdd:pfam00005    1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLtDDERKSLRKEIGYVFQDPQLFPRLTVRENL 80
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1443 LLYGSIKvpHWTKKQLHEEVKRTLKDTGLYSHRHKRVG----TLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:pfam00005   81 RLGLLLK--GLSKREKDARAEEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
1349-1564 2.93e-34

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 136.38  E-value: 2.93e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGVCMQ 1428
Cdd:COG3842      6 LELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDV-TGLPPEKRNVGMVFQ 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHlLLYGsIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:COG3842     85 DYALFPHLTVAEN-VAFG-LRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEP 162
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1509 STGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:COG3842    163 LSALDAKLREEMREELRRlqRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTP 220
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
1351-1556 3.81e-34

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 131.79  E-value: 3.81e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-KTDLHT-VRKNMGVCMQ 1428
Cdd:cd03224      3 VENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDItGLPPHErARAGIGYVPE 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHLLLYGSIKVPHWTKKQLhEEVKRTLKDtgLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:cd03224     83 GRRIFPELTVEENLLLGAYARRRAKRKARL-ERVYELFPR--LKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEP 159
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 1509 STGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03224    160 SEGLAPKIVEEIFEAIRElRDEGVTILLVEQNARFALEIADRAYVLERG 208
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
1353-1564 4.77e-34

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 131.90  E-value: 4.77e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHT---VRKNMGVCMQH 1429
Cdd:cd03218      5 NLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDI-TKLPMhkrARLGIGYLPQE 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYLTTKEHLLLYGSIKVPhwTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPS 1509
Cdd:cd03218     84 ASIFRKLTVEENILAVLEIRGL--SKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEPF 161
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1510 TGVDPCSRRSIWDVIsKNKTARTI-ILST-HHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:cd03218    162 AGVDPIAVQDIQKII-KILKDRGIgVLITdHNVRETLSITDRAYIIYEGKVLAEGTP 217
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
1349-1556 6.80e-34

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 131.53  E-value: 6.80e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGA-----SAGTIFVYGKDI---KTDLHTVR 1420
Cdd:cd03260      1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKDIydlDVDVLELR 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1421 KNMGVCMQHDVLFSyLTTKEHLL----LYGSikvphWTKKQLHEEVKRTLKDTGL--YSHRHKRVGTLSGGMKRKLSISI 1494
Cdd:cd03260     81 RRVGMVFQKPNPFP-GSIYDNVAyglrLHGI-----KLKEELDERVEEALRKAALwdEVKDRLHALGLSGGQQQRLCLAR 154
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1495 ALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03260    155 ALANEPEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNG 216
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
1349-1556 2.20e-33

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 130.01  E-value: 2.20e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSK----VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT----DLHTVR 1420
Cdd:cd03258      2 IELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLlsgkELRKAR 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1421 KNMGVCMQHDVLFSYLTTKEHLLLygSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGS 1500
Cdd:cd03258     82 RRIGMIFQHFNLLSSRTVFENVAL--PLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNP 159
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1501 RVVILDEPSTGVDPCSRRSIWDVISK-NKTAR-TIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03258    160 KVLLCDEATSALDPETTQSILALLRDiNRELGlTIVLITHEMEVVKRICDRVAVMEKG 217
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
2275-2475 2.24e-33

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 130.59  E-value: 2.24e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgslgHVDSHSSLVGYCPQEDALDDL--VTVE 2352
Cdd:COG1121     21 VLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGK-----PPRRARRRIGYVPQRAEVDWDfpITVR 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2353 E----HLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSK 2428
Cdd:COG1121     96 DvvlmGRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATE 175
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2462571778 2429 RHLWKIISEEVQNKCSVILTSHSMEECEALCTRLaIMVNGKFQCIGS 2475
Cdd:COG1121    176 EALYELLRELRREGKTILVVTHDLGAVREYFDRV-LLLNRGLVAHGP 221
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
1349-1556 3.61e-33

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 128.80  E-value: 3.61e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI---KTDLHTVRKNMGV 1425
Cdd:cd03262      1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLtddKKNINELRQKVGM 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1426 CMQHDVLFSYLTTKEHLLLyGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVIL 1505
Cdd:cd03262     81 VFQQFNLFPHLTVLENITL-APIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLF 159
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1506 DEPSTGVDPCSRRSIWDVIsKN--KTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03262    160 DEPTSALDPELVGEVLDVM-KDlaEEGMTMVVVTHEMGFAREVADRVIFMDDG 211
galliderm_ABC TIGR03740
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ...
1352-1559 4.92e-33

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.


Pssm-ID: 163452 [Multi-domain]  Cd Length: 223  Bit Score: 128.67  E-value: 4.92e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1352 HGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKD-IKTDLHtvrkNMGVCMQHD 1430
Cdd:TIGR03740    4 KNLSKRFGKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPwTRKDLH----KIGSLIESP 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSYLTTKEHLllygsiKVpHWTKKQLHE-EVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPS 1509
Cdd:TIGR03740   80 PLYENLTARENL------KV-HTTLLGLPDsRIDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLILDEPT 152
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1510 TGVDPCSRRSIWDVI-SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLR 1559
Cdd:TIGR03740  153 NGLDPIGIQELRELIrSFPEQGITVILSSHILSEVQQLADHIGIISEGVLG 203
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
1350-1562 1.19e-32

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 126.01  E-value: 1.19e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1350 ALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVcmq 1428
Cdd:cd03214      1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASlSPKELARKIAY--- 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 hdvlfsylttkehlllygsikVPhwtkkQLheevkrtLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:cd03214     78 ---------------------VP-----QA-------LELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEP 124
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 1509 STGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCG 1562
Cdd:cd03214    125 TSHLDIAHQIELLELLRRlaRERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
1349-1556 1.78e-32

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 127.89  E-value: 1.78e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTG-LFGASAGTIFVYGKDI-KTDLHTVRKNMGVC 1426
Cdd:COG1119      4 LELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGdLPPTYGNDVRLFGERRgGEDVWELRKRIGLV 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 ---MQHDvlFSYLTTKEHLLL---YGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGS 1500
Cdd:COG1119     84 spaLQLR--FPRDETVLDVVLsgfFDSIGLYREPTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDP 161
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1501 RVVILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDE--AEVlsDRIAFLEQG 1556
Cdd:COG1119    162 ELLILDEPTAGLDLGARELLLALLDKlaAEGAPTLVLVTHHVEEipPGI--THVLLLKDG 219
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
1349-1582 2.61e-32

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 134.26  E-value: 2.61e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSK-----VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT----DLHTV 1419
Cdd:COG1123    261 LEVRNLSKRYPVRgkggvRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKlsrrSLREL 340
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1420 RKNMGVCMQH--DVLFSYLTTKEH----LLLYGsikvpHWTKKQLHEEVKRTLKDTGL-YSHRHKRVGTLSGGMKRKLSI 1492
Cdd:COG1123    341 RRRVQMVFQDpySSLNPRMTVGDIiaepLRLHG-----LLSRAERRERVAELLERVGLpPDLADRYPHELSGGQRQRVAI 415
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1493 SIALIGGSRVVILDEPSTGVDPCSRRSIWDVIS--KNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPfylKEA 1570
Cdd:COG1123    416 ARALALEPKLLILDEPTSALDVSVQAQILNLLRdlQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPT---EEV 492
                          250
                   ....*....|..
gi 2462571778 1571 FGDGYHLtLTKK 1582
Cdd:COG1123    493 FANPQHP-YTRA 503
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
2257-2465 3.24e-32

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 126.43  E-value: 3.24e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2257 VQLYCLTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgslghVDSHSSLV 2336
Cdd:cd03293      1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEP-----VTGPGPDR 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2337 GYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLL 2416
Cdd:cd03293     76 GYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLL 155
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 2417 DEPSSGMDPKSKRH----LWKIISEEVQnkcSVILTSHSMEECEALCTRLAIM 2465
Cdd:cd03293    156 DEPFSALDALTREQlqeeLLDIWRETGK---TVLLVTHDIDEAVFLADRVVVL 205
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
1334-1564 4.49e-32

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 127.76  E-value: 4.49e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1334 FSSNIEPEPKDLTVGVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI- 1412
Cdd:cd03294     10 FGKNPQKAFKLLAKGKSKEEILKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIa 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1413 ---KTDLHTVR-KNMGVCMQHDVLFSYLTTKEHLLlYGsIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKR 1488
Cdd:cd03294     90 amsRKELRELRrKKISMVFQSFALLPHRTVLENVA-FG-LEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQ 167
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1489 KLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:cd03294    168 RVGLARALAVDPDILLMDEAFSALDPLIRREMQDELLRlqAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTP 245
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
2262-2479 6.71e-32

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 125.91  E-value: 6.71e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK--TG-------SLGhvdsh 2332
Cdd:COG1137      9 LVKSY----GKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEdiTHlpmhkraRLG----- 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2333 sslVGYCPQEDAL-DDLvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKP 2411
Cdd:COG1137     80 ---IGYLPQEASIfRKL-TVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNP 155
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2412 SILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:COG1137    156 KFILLDEPFAGVDPIAVADIQKIIRHLKERGIGVLITDHNVRETLGICDRAYIISEGKVLAEGTPEEI 223
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
1349-1556 6.88e-32

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 123.65  E-value: 6.88e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGS--KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGV 1425
Cdd:cd03228      1 IEFKNVSFSYPGrpKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDlDLESLRKNIAY 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1426 CMQHDVLFSylttkehlllyGSIKvphwtkkqlhEEVkrtlkdtglyshrhkrvgtLSGGMKRKLSISIALIGGSRVVIL 1505
Cdd:cd03228     81 VPQDPFLFS-----------GTIR----------ENI-------------------LSGGQRQRIAIARALLRDPPILIL 120
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1506 DEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEvLSDRIAFLEQG 1556
Cdd:cd03228    121 DEATSALDPETEALILEALRALAKGKTVIVIAHRLSTIR-DADRIIVLDDG 170
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
2270-2469 1.24e-31

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 125.14  E-value: 1.24e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2270 HKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI---RNKTGSLGHVDSHSSLVGycpQEDALD 2346
Cdd:cd03267     31 YREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVaglVPWKRRKKFLRRIGVVFG---QKTQLW 107
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2347 DLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPK 2426
Cdd:cd03267    108 WDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVV 187
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 2462571778 2427 SKRHLWKIISEEVQN-KCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03267    188 AQENIRNFLKEYNRErGTTVLLTSHYMKDIEALARRVLVIDKGR 231
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
2262-2479 2.75e-31

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 124.31  E-value: 2.75e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSL-VGYCP 2340
Cdd:TIGR04406    7 LIKSY----KKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLPMHERARLgIGYLP 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2341 QEDALDDLVTVEEHLY-FYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEP 2419
Cdd:TIGR04406   83 QEASIFRKLTVEENIMaVLEIRKDLDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDEP 162
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2420 SSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:TIGR04406  163 FAGVDPIAVGDIKKIIKHLKERGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEI 222
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
1351-1556 5.44e-31

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 123.45  E-value: 5.44e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGS-KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI----KTDLHTVRKNMGV 1425
Cdd:cd03256      3 VENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDInklkGKALRQLRRQIGM 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1426 CMQHDVLFSYLTTKEHLLlygSIKVPHWTK-----KQLHEEVKR----TLKDTGLYSHRHKRVGTLSGGMKRKLSISIAL 1496
Cdd:cd03256     83 IFQQFNLIERLSVLENVL---SGRLGRRSTwrslfGLFPKEEKQralaALERVGLLDKAYQRADQLSGGQQQRVAIARAL 159
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1497 IGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTAR--TIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03256    160 MQQPKLILADEPVASLDPASSRQVMDLLKRINREEgiTVIVSLHQVDLAREYADRIVGLKDG 221
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
2273-2481 6.81e-31

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 122.93  E-value: 6.81e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2273 IIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgslghvdshsSLVGYCPQEDA-------- 2344
Cdd:cd03219     13 LVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGE-----------DITGLPPHEIArlgigrtf 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2345 -----LDDLvTVEE----------HLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIG 2409
Cdd:cd03219     82 qiprlFPEL-TVLEnvmvaaqartGSGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALAT 160
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2410 KPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKS 2481
Cdd:cd03219    161 DPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRN 232
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
1349-1556 9.11e-31

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 122.21  E-value: 9.11e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGS----KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-------KTDLh 1417
Cdd:cd03255      1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDIsklsekeLAAF- 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1418 tVRKNMGVCMQHDVLFSYLTTKEHLLLYGSI-KVPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIAL 1496
Cdd:cd03255     80 -RRRHIGFVFQSFNLLPDLTALENVELPLLLaGVP---KKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARAL 155
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1497 IGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTA-RTIILSTHHLDEAEvLSDRIAFLEQG 1556
Cdd:cd03255    156 ANDPKIILADEPTGNLDSETGKEVMELLRElNKEAgTTIVVVTHDPELAE-YADRIIELRDG 216
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
1343-1556 3.61e-30

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 120.86  E-value: 3.61e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1343 KDLTVGvalhgvtkiYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHT---V 1419
Cdd:COG0410      7 ENLHAG---------YGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDI-TGLPPhriA 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1420 RKNMGVCMQHDVLFSYLTTKEHLLL----YGSIKVPHWTKKQLHEEVKRtlkdtgLYSHRHKRVGTLSGGMKRKLSISIA 1495
Cdd:COG0410     77 RLGIGYVPEGRRIFPSLTVEENLLLgayaRRDRAEVRADLERVYELFPR------LKERRRQRAGTLSGGEQQMLAIGRA 150
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1496 LIGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:COG0410    151 LMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRlNREGVTILLVEQNARFALEIADRAYVLERG 212
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
1349-1559 6.35e-30

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 119.67  E-value: 6.35e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGVCMQ 1428
Cdd:cd03301      1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDV-TDLPPKDRDIAMVFQ 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHLLLygSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:cd03301     80 NYALYPHMTVYDNIAF--GLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEP 157
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1509 STGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLR 1559
Cdd:cd03301    158 LSNLDAKLRVQMRAELKRlqQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQ 210
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
2275-2469 1.04e-29

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 120.14  E-value: 1.04e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSH-------------SSLvgycpq 2341
Cdd:COG0411     19 AVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGR--DITGLPPHriarlgiartfqnPRL------ 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 edaLDDLvTVEEHL----------YFYARVHGIP-----EKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALA 2406
Cdd:COG0411     91 ---FPEL-TVLENVlvaaharlgrGLLAALLRLPrarreEREARERAEELLERVGLADRADEPAGNLSYGQQRRLEIARA 166
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2407 LIGKPSILLLDEPSSGMDPKSKRHLWKIIsEEV--QNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:COG0411    167 LATEPKLLLLDEPAAGLNPEETEELAELI-RRLrdERGITILLIEHDMDLVMGLADRIVVLDFGR 230
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
1356-1556 1.16e-29

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 118.51  E-value: 1.16e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1356 KIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKtdLHTVRKNMGVCMQH--DVLF 1433
Cdd:cd03226      8 SYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIK--AKERRKSIGYVMQDvdYQLF 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1434 SYlTTKEHLLLygsikvphwTKKQLHEEVKRT---LKDTGLYS--HRHKRvgTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:cd03226     86 TD-SVREELLL---------GLKELDAGNEQAetvLKDLDLYAlkERHPL--SLSGGQKQRLAIAAALLSGKDLLIFDEP 153
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 1509 STGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03226    154 TSGLDYKNMERVGELIRElAAQGKAVIVITHDYEFLAKVCDRVLLLANG 202
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
2274-2474 1.61e-29

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 118.40  E-value: 1.61e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgslgHVDSHSSLVGYCPQEDALD-DL-VTV 2351
Cdd:cd03235     13 PVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGK-----PLEKERKRIGYVPQRRSIDrDFpISV 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 EE----HLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKS 2427
Cdd:cd03235     88 RDvvlmGLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKT 167
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2462571778 2428 KRHLWKIISEEVQNKCSVILTSHSMEECEALCTRlAIMVNGKFQCIG 2474
Cdd:cd03235    168 QEDIYELLRELRREGMTILVVTHDLGLVLEYFDR-VLLLNRTVVASG 213
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
2262-2469 2.13e-29

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 118.38  E-value: 2.13e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK---TGSLGHVDSHSSLVGY 2338
Cdd:cd03257      7 LSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKdllKLSRRLRKIRRKEIQM 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2339 CPQE--DALDDLVTVEEHLYFYARVHGIPEKD--IKETVHKLLRRLHLMP-FKDRATSMCSYGTKRKLSTALALIGKPSI 2413
Cdd:cd03257     87 VFQDpmSSLNPRMTIGEQIAEPLRIHGKLSKKeaRKEAVLLLLVGVGLPEeVLNRYPHELSGGQRQRVAIARALALNPKL 166
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 2414 LLLDEPSSGMDPKSKRHLWKIISE-EVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03257    167 LIADEPTSALDVSVQAQILDLLKKlQEELGLTLLFITHDLGVVAKIADRVAVMYAGK 223
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
2262-2479 2.27e-29

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 125.40  E-value: 2.27e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLIHKKII-AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK-TGSLGHVD--SHSSLVG 2337
Cdd:COG1123    266 LSKRYPVRGKGGVrAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKdLTKLSRRSlrELRRRVQ 345
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2338 YCPQ--EDALDDLVTVEEHLYFYARVHGI-PEKDIKETVHKLLRRLHLMP-FKDRATSMCSYGTKRKLSTALALIGKPSI 2413
Cdd:COG1123    346 MVFQdpYSSLNPRMTVGDIIAEPLRLHGLlSRAERRERVAELLERVGLPPdLADRYPHELSGGQRQRVAIARALALEPKL 425
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2414 LLLDEPSSGMDPKSKRHLWKIIsEEVQNK--CSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:COG1123    426 LILDEPTSALDVSVQAQILNLL-RDLQRElgLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEV 492
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
2274-2487 5.83e-29

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 117.34  E-value: 5.83e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSHSSLVGYCPQEDALDDLVTVEE 2353
Cdd:cd03300     14 VALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGK--DITNLPPHKRPVNTVFQNYALFPHLTVFE 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 HLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLwK 2433
Cdd:cd03300     92 NIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLKLRKDM-Q 170
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2434 IISEEVQNKC--SVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI----KSRFGRGF 2487
Cdd:cd03300    171 LELKRLQKELgiTFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIyeepANRFVADF 230
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
1352-1571 6.32e-29

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 117.44  E-value: 6.32e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1352 HGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDL--HT-VRKNMGVCMQ 1428
Cdd:COG1137      7 ENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDI-THLpmHKrARLGIGYLPQ 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHLLLYGSIKVPhwTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:COG1137     86 EASIFRKLTVEDNILAVLELRKL--SKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFILLDEP 163
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 1509 STGVDPCSRRSIWDVISKNKTaRTI-ILST-HHLDEAEVLSDRIAFLEQGGLRCCGSP-----------FYLKEAF 1571
Cdd:COG1137    164 FAGVDPIAVADIQKIIRHLKE-RGIgVLITdHNVRETLGICDRAYIISEGKVLAEGTPeeilnnplvrkVYLGEDF 238
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
2269-2470 2.79e-28

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 114.66  E-value: 2.79e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2269 IHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGhvdSHSSLVGYCPQEdaLDD- 2347
Cdd:cd03226      9 YKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAK---ERRKSIGYVMQD--VDYq 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2348 --LVTVEEHLYFyarvhGIPEK-DIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:cd03226     84 lfTDSVREELLL-----GLKELdAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLD 158
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462571778 2425 PKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKF 2470
Cdd:cd03226    159 YKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAI 204
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
1339-1577 2.93e-28

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 122.57  E-value: 2.93e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1339 EPEPKDLTVGVALHGVTKIY--GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-D 1415
Cdd:COG4987    324 EPAPAPGGPSLELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDlD 403
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1416 LHTVRKNMGVCMQHDVLFSylTT-KEHLLLygsikvphwTKKQL-HEEVKRTLKDTGLyshrHK-----------RVG-- 1480
Cdd:COG4987    404 EDDLRRRIAVVPQRPHLFD--TTlRENLRL---------ARPDAtDEELWAALERVGL----GDwlaalpdgldtWLGeg 468
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1481 --TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEvLSDRIAFLEQGGL 1558
Cdd:COG4987    469 grRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLLITHRLAGLE-RMDRILVLEDGRI 547
                          250
                   ....*....|....*....
gi 2462571778 1559 RCCGSPFYLKEAFGDGYHL 1577
Cdd:COG4987    548 VEQGTHEELLAQNGRYRQL 566
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
2244-2493 2.95e-28

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 119.55  E-value: 2.95e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2244 RLRVESGAAEFDLVQLYCLTKTYQLIHkkiiAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKt 2323
Cdd:PRK11607     7 RPQAKTRKALTPLLEIRNLTKSFDGQH----AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGV- 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2324 gSLGHVDSHSSLVGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLST 2403
Cdd:PRK11607    82 -DLSHVPPYQRPINMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2404 ALALIGKPSILLLDEPSSGMDPKSK-RHLWKI--ISEEVQNKCsvILTSHSMEECEALCTRLAIMVNGKFQCIGS----L 2476
Cdd:PRK11607   161 ARSLAKRPKLLLLDEPMGALDKKLRdRMQLEVvdILERVGVTC--VMVTHDQEEAMTMAGRIAIMNRGKFVQIGEpeeiY 238
                          250
                   ....*....|....*..
gi 2462571778 2477 QHIKSRFGRGFTVKVHL 2493
Cdd:PRK11607   239 EHPTTRYSAEFIGSVNV 255
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
1349-1556 3.22e-28

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 121.67  E-value: 3.22e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKdiKTDLHTVRK--NMGVC 1426
Cdd:COG3845      6 LELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGK--PVRIRSPRDaiALGIG 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 M--QHDVLFSYLTTKEHLLL-YGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVV 1503
Cdd:COG3845     84 MvhQHFMLVPNLTVAENIVLgLEPTKGGRLDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGARIL 163
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1504 ILDEPSTGVDPCSRRSIWDVIsKNKTA--RTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:COG3845    164 ILDEPTAVLTPQEADELFEIL-RRLAAegKSIIFITHKLREVMAIADRVTVLRRG 217
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
1339-1564 6.14e-28

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 121.79  E-value: 6.14e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1339 EPEPKDLTVGVALHGVTKIY-GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DL 1416
Cdd:COG4988    327 APLPAAGPPSIELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDlDP 406
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1417 HTVRKNMGVCMQHDVLFsYLTTKEHLLLYGsikvPHWTKKQLHE--------EVKRTLKDtGLyshrHKRVG----TLSG 1484
Cdd:COG4988    407 ASWRRQIAWVPQNPYLF-AGTIRENLRLGR----PDASDEELEAaleaagldEFVAALPD-GL----DTPLGeggrGLSG 476
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1485 GMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEvLSDRIAFLEQGGLRCCGSP 1564
Cdd:COG4988    477 GQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKGRTVILITHRLALLA-QADRILVLDDGRIVEQGTH 555
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
1338-1572 6.26e-28

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 123.70  E-value: 6.26e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1338 IEPEPKDLTVGVAL--HGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTD 1415
Cdd:NF033858   254 IPPRPADDDDEPAIeaRGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAG 333
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1416 LHTVRKNMGVCMQHDVLFSYLTTKEHLLLYGsiKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIA 1495
Cdd:NF033858   334 DIATRRRVGYMSQAFSLYGELTVRQNLELHA--RLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVA 411
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1496 LIGGSRVVILDEPSTGVDPCSRRSIWDVISknKTAR----TIILSTHHLDEAEvLSDRIAFLEQGGLRCCGSPFYLKEAF 1571
Cdd:NF033858   412 VIHKPELLILDEPTSGVDPVARDMFWRLLI--ELSRedgvTIFISTHFMNEAE-RCDRISLMHAGRVLASDTPAALVAAR 488

                   .
gi 2462571778 1572 G 1572
Cdd:NF033858   489 G 489
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
1364-1564 1.67e-27

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 113.20  E-value: 1.67e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1364 VDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGVCMQHDVLFSYLTTKEHLL 1443
Cdd:cd03299     15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDI-TNLPPEKRDISYVPQNYALFPHMTVYKNIA 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1444 lYGsIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIW-- 1521
Cdd:cd03299     94 -YG-LKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLRee 171
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2462571778 1522 --DVISKNKTarTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:cd03299    172 lkKIRKEFGV--TVLHVTHDFEEAWALADKVAIMLNGKLIQVGKP 214
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
1353-1564 2.01e-27

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 113.14  E-value: 2.01e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDL--HT-VRKNMGVCMQH 1429
Cdd:TIGR04406    6 NLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDI-THLpmHErARLGIGYLPQE 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYLTTKEHLLLYGSIkVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPS 1509
Cdd:TIGR04406   85 ASIFRKLTVEENIMAVLEI-RKDLDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDEPF 163
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1510 TGVDPCSRRSIWDVISKNKtARTI-ILST-HHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:TIGR04406  164 AGVDPIAVGDIKKIIKHLK-ERGIgVLITdHNVRETLDICDRAYIISDGKVLAEGTP 219
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
1349-1564 3.59e-27

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 115.56  E-value: 3.59e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGvcM- 1427
Cdd:COG3839      4 LELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDV-TDLPPKDRNIA--Mv 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 -QHDVLFSYLTTKEHlLLYGsIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILD 1506
Cdd:COG3839     81 fQSYALYPHMTVYEN-IAFP-LKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLD 158
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1507 EPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:COG3839    159 EPLSNLDAKLRVEMRAEIKRlhRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTP 218
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
2262-2475 4.63e-27

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 115.20  E-value: 4.63e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgsLGHVDSHSSLVGYCPQ 2341
Cdd:COG3842     11 VSKRY----GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRD--VTGLPPEKRNVGMVFQ 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTK-RklsTALA--LIGKPSILLLDE 2418
Cdd:COG3842     85 DYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQqR---VALAraLAPEPRVLLLDE 161
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2419 PSSGMDPKSKRHLWkiisEEV-----QNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGS 2475
Cdd:COG3842    162 PLSALDAKLREEMR----EELrrlqrELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGT 219
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
1366-1562 4.68e-27

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 111.59  E-value: 4.68e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1366 NLNLNFYEGHITSLLGPNGAGKTTTISMLTGLF---GASAGTIFVYGKDIKTdlHTVRKNMGVCMQHDVLFSYLTTKEHL 1442
Cdd:cd03234     25 DVSLHVESGQVMAILGSSGSGKTTLLDAISGRVeggGTTSGQILFNGQPRKP--DQFQKCVAYVRQDDILLPGLTVRETL 102
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1443 LLYGSIKVP-HWTKKQLHEEVKRT-LKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSI 1520
Cdd:cd03234    103 TYTAILRLPrKSSDAIRKKRVEDVlLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTALNL 182
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2462571778 1521 WDVISK-NKTARTIILSTHHlDEAEV--LSDRIAFLEQGGLRCCG 1562
Cdd:cd03234    183 VSTLSQlARRNRIVILTIHQ-PRSDLfrLFDRILLLSSGEIVYSG 226
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1349-1575 4.81e-27

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 111.89  E-value: 4.81e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHT---VRKNMGV 1425
Cdd:PRK11614     6 LSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDI-TDWQTakiMREAVAI 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1426 CMQHDVLFSYLTTKEHLLLYGSIKvphwTKKQLHEEVKRTLK-DTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:PRK11614    85 VPEGRRVFSRMTVEENLAMGGFFA----ERDQFQERIKWVYElFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLL 160
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGG--LRCCGSPFYLKEAFGDGY 1575
Cdd:PRK11614   161 LDEPSLGLAPIIIQQIFDTIEQlREQGMTIFLVEQNANQALKLADRGYVLENGHvvLEDTGDALLANEAVRSAY 234
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1349-1558 8.39e-27

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 110.90  E-value: 8.39e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSK----VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT----DLHTVR 1420
Cdd:COG1136      5 LELRNLTKSYGTGegevTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSlserELARLR 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1421 -KNMGVCMQHDVLFSYLTTKEHL---LLYGSIKvphwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIAL 1496
Cdd:COG1136     85 rRHIGFVFQFFNLLPELTALENValpLLLAGVS-----RKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARAL 159
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1497 IGGSRVVILDEPsTG-VDPCSRRSIWDVISK-NKTA-RTIILSTHHLDEAEvLSDRIAFLEQGGL 1558
Cdd:COG1136    160 VNRPKLILADEP-TGnLDSKTGEEVLELLRElNRELgTTIVMVTHDPELAA-RADRVIRLRDGRI 222
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
1348-1564 9.06e-27

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 111.28  E-value: 9.06e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1348 GVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGVCM 1427
Cdd:cd03296      2 SIEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDA-TDVPVQERNVGFVF 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QHDVLFSYLTTKEHLLLYGSIK--VPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVIL 1505
Cdd:cd03296     81 QHYALFRHMTVFDNVAFGLRVKprSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLL 160
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1506 DEPSTGVDPCSRRSI--WDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:cd03296    161 DEPFGALDAKVRKELrrWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTP 221
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
2269-2469 9.70e-27

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 108.67  E-value: 9.70e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2269 IHKK---IIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgslghVDSHSslvgycPQEdal 2345
Cdd:cd03216      6 ITKRfggVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKE-----VSFAS------PRD--- 71
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2346 ddlvtveehlyfyARVHGIpekdikETVHKLlrrlhlmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEPSSGMDP 2425
Cdd:cd03216     72 -------------ARRAGI------AMVYQL-----------------SVGERQMVEIARALARNARLLILDEPTAALTP 115
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 2462571778 2426 KSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03216    116 AEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGR 159
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
2278-2482 1.26e-26

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 110.89  E-value: 1.26e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSslVGYCPQEDALDDLVTVEEHLYF 2357
Cdd:cd03299     17 NVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKRD--ISYVPQNYALFPHMTVYKNIAY 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2358 YARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSK---RHLWKI 2434
Cdd:cd03299     95 GLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKeklREELKK 174
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 2435 ISEEvqNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKSR 2482
Cdd:cd03299    175 IRKE--FGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKK 220
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
2276-2475 1.43e-26

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 111.29  E-value: 1.43e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSH--SSLVGYCPQEDALDDLVTVEE 2353
Cdd:COG1120     17 LDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGR--DLASLSRRelARRIAYVPQEPPAPFGLTVRE 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 --------HLYFYARVhgiPEKDiKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDP 2425
Cdd:COG1120     95 lvalgrypHLGLFGRP---SAED-REAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLLDEPTSHLDL 170
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 2426 KSKRHLWKIISEEVQNK-CSVILTSHSMEECEALCTRLAIMVNGKFQCIGS 2475
Cdd:COG1120    171 AHQLEVLELLRRLARERgRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGP 221
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
1351-1558 1.48e-26

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 109.52  E-value: 1.48e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQH 1429
Cdd:COG4619      3 LEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAmPPPEWRRQVAYVPQE 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYlTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLyshRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPS 1509
Cdd:COG4619     83 PALWGG-TVRDNLPFPFQLRERKFDRERALELLERLGLPPDI---LDKPVERLSGGERQRLALIRALLLQPDVLLLDEPT 158
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1510 TGVDPCSRRSIWDVISKNKTA--RTIILSTHHLDEAEVLSDRIAFLEQGGL 1558
Cdd:COG4619    159 SALDPENTRRVEELLREYLAEegRAVLWVSHDPEQIERVADRVLTLEAGRL 209
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
1351-1556 1.87e-26

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 109.90  E-value: 1.87e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIY----GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI----KTDLHTVRKN 1422
Cdd:cd03257      4 VKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLlklsRRLRKIRRKE 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1423 MGVCMQhDVLFS---YLTTKEHL---LLygsIKVPHWTKKQLHEEVKRTLKDTGLYSHR-HKRVGTLSGGMKRKLSISIA 1495
Cdd:cd03257     84 IQMVFQ-DPMSSlnpRMTIGEQIaepLR---IHGKLSKKEARKEAVLLLLVGVGLPEEVlNRYPHELSGGQRQRVAIARA 159
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1496 LIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTAR--TIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03257    160 LALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELglTLLFITHDLGVVAKIADRVAVMYAG 222
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
1362-1573 2.01e-26

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 111.32  E-value: 2.01e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1362 VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTD---LHTVRKNMGVCMQH--DVLFSyl 1436
Cdd:PRK13639    16 EALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDkksLLEVRKTVGIVFQNpdDQLFA-- 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1437 TTKEHLLLYG--SIKVPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDP 1514
Cdd:PRK13639    94 PTVEEDVAFGplNLGLS---KEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDP 170
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1515 CSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPfylKEAFGD 1573
Cdd:PRK13639   171 MGASQIMKLLYDlNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTP---KEVFSD 227
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
2271-2469 2.49e-26

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 110.17  E-value: 2.49e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2271 KKIIavNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGN---IL-----------IRNKtgsLGHVDShsSLV 2336
Cdd:COG1119     16 KTIL--DDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNdvrLFgerrggedvweLRKR---IGLVSP--ALQ 88
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2337 GYCPQEDalddlvTVEEHLY--FYARVhGI---PEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKP 2411
Cdd:COG1119     89 LRFPRDE------TVLDVVLsgFFDSI-GLyrePTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDP 161
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 2412 SILLLDEPSSGMDPKSKRHLWKIISEEVQN-KCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:COG1119    162 ELLILDEPTAGLDLGARELLLALLDKLAAEgAPTLVLVTHHVEEIPPGITHVLLLKDGR 220
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
2262-2469 6.18e-26

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 108.82  E-value: 6.18e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI-------------RNKTGSLGH 2328
Cdd:cd03258      7 VSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVdgtdltllsgkelRKARRRIGM 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2329 VDSHSSLvgycpqedaLDDLvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALI 2408
Cdd:cd03258     87 IFQHFNL---------LSSR-TVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALA 156
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 2409 GKPSILLLDEPSSGMDPKSKRHLWKIISeEVQNK--CSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03258    157 NNPKVLLCDEATSALDPETTQSILALLR-DINRElgLTIVLITHEMEVVKRICDRVAVMEKGE 218
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
2275-2479 7.66e-26

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 114.62  E-value: 7.66e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGdIIPS----SGNILIRNKTGSLGHVDSHSSLVGYCPQE-DALDDLV 2349
Cdd:COG1123     21 AVDGVSLTIAPGETVALVGESGSGKSTLALALMG-LLPHggriSGEVLLDGRDLLELSEALRGRRIGMVFQDpMTQLNPV 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2350 TVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKR 2429
Cdd:COG1123    100 TVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALDVTTQA 179
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 2430 HLWKIISEEVQNK-CSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:COG1123    180 EILDLLRELQRERgTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEI 230
cbiO PRK13637
energy-coupling factor transporter ATPase;
2275-2475 9.16e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 109.75  E-value: 9.16e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRN-----KTGSLGHVDSHSSLVGYCPQEDALDDlv 2349
Cdd:PRK13637    22 ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGvditdKKVKLSDIRKKVGLVFQYPEYQLFEE-- 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2350 TVEEHLYFYARVHGIPEKDIKETVHKLLR--RLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKS 2427
Cdd:PRK13637   100 TIEKDIAFGPINLGLSEEEIENRVKRAMNivGLDYEDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKG 179
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 2428 KRHLWKIISE-EVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGS 2475
Cdd:PRK13637   180 RDEILNKIKElHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGT 228
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
2275-2469 9.69e-26

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 116.76  E-value: 9.69e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrnktgsLGH-VDSHS----SLVGYCPQEDALDDLV 2349
Cdd:NF033858   281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWL------FGQpVDAGDiatrRRVGYMSQAFSLYGEL 354
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2350 TVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKR 2429
Cdd:NF033858   355 TVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARD 434
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 2462571778 2430 HLWKIISE-EVQNKCSVILTSHSMEECEaLCTRLAIMVNGK 2469
Cdd:NF033858   435 MFWRLLIElSREDGVTIFISTHFMNEAE-RCDRISLMHAGR 474
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
1359-1564 1.27e-25

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 113.84  E-value: 1.27e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1359 GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLF---GASAGTIFVYGKDIKTDLHTVR-KNMGVCMQH-DVLF 1433
Cdd:COG1123     17 GDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLphgGRISGEVLLDGRDLLELSEALRgRRIGMVFQDpMTQL 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1434 SYLTTKEHLLLygSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVD 1513
Cdd:COG1123     97 NPVTVGDQIAE--ALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALD 174
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1514 PCSRRSIWDVISKNKTAR--TIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:COG1123    175 VTTQAEILDLLRELQRERgtTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPP 227
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
1349-1556 1.36e-25

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 105.20  E-value: 1.36e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIktDLHTVR--KNMGVC 1426
Cdd:cd03216      1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEV--SFASPRdaRRAGIA 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 MQHdvlfsylttkehlllygsikvphwtkkQlheevkrtlkdtglyshrhkrvgtLSGGMKRKLSISIALIGGSRVVILD 1506
Cdd:cd03216     79 MVY---------------------------Q------------------------LSVGERQMVEIARALARNARLLILD 107
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1507 EPSTGVDPCSRRSIWDVISKNKTA-RTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03216    108 EPTAALTPAEVERLFKVIRRLRAQgVAVIFISHRLDEVFEIADRVTVLRDG 158
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
2275-2469 1.47e-25

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 107.27  E-value: 1.47e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTG--DII---PSSGNILIRNKT--GSLGHVDSHSSLVGYCPQEDALDD 2347
Cdd:cd03260     15 ALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRlnDLIpgaPDEGEVLLDGKDiyDLDVDVLELRRRVGMVFQKPNPFP 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2348 LvTVEEHLYFYARVHGI-PEKDIKETVHKLLRRLHLMP-FKDRATSM-CSYGTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:cd03260     95 G-SIYDNVAYGLRLHGIkLKEELDERVEEALRKAALWDeVKDRLHALgLSGGQQQRLCLARALANEPEVLLLDEPTSALD 173
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2462571778 2425 PKSKRHLWKIIsEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03260    174 PISTAKIEELI-AELKKEYTIVIVTHNMQQAARVADRTAFLLNGR 217
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
2264-2469 1.85e-25

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 106.85  E-value: 1.85e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2264 KTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgslghvdshSSLVGYcpqED 2343
Cdd:cd03220     26 LGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRV---------SSLLGL---GG 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2344 ALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGM 2423
Cdd:cd03220     94 GFNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVG 173
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462571778 2424 DPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03220    174 DAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGK 219
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
2257-2453 1.94e-25

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 106.68  E-value: 1.94e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2257 VQLYCLTKTYQlihKKIIAVNNISIGIPAGE-CFgLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVdSHSSL 2335
Cdd:COG2884      2 IRFENVSKRYP---GGREALSDVSLEIEKGEfVF-LTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQ--DLSRL-KRREI 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2336 ------VGYCPQeDA--LDDLvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLmpfKDRATSMC---SYGTKRKLSTA 2404
Cdd:COG2884     75 pylrrrIGVVFQ-DFrlLPDR-TVYENVALPLRVTGKSRKEIRRRVREVLDLVGL---SDKAKALPhelSGGEQQRVAIA 149
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 2405 LALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSME 2453
Cdd:COG2884    150 RALVNRPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLE 198
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
1341-1577 2.92e-25

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 114.55  E-value: 2.92e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1341 EPKDLTVGVALHGVTKIYG--SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLH 1417
Cdd:COG2274    466 SLPRLKGDIELENVSFRYPgdSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQiDPA 545
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1418 TVRKNMGVCMQHDVLFSylttkehlllyGSIK------VPHWTKkqlhEEVKRTLKDTGLYS--HRHK-----RVG---- 1480
Cdd:COG2274    546 SLRRQIGVVLQDVFLFS-----------GTIRenitlgDPDATD----EEIIEAARLAGLHDfiEALPmgydtVVGeggs 610
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1481 TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEvLSDRIAFLEQGGLRC 1560
Cdd:COG2274    611 NLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVIIIAHRLSTIR-LADRIIVLDKGRIVE 689
                          250
                   ....*....|....*..
gi 2462571778 1561 CGSPFYLKEAFGDGYHL 1577
Cdd:COG2274    690 DGTHEELLARKGLYAEL 706
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
1351-1556 3.15e-25

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 109.85  E-value: 3.15e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHD 1430
Cdd:COG1118      5 VRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFTNLPPRERRVGFVFQHY 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSYLTTKEHlLLYGsIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:COG1118     85 ALFPHMTVAEN-IAFG-LRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPFG 162
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 1511 GVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:COG1118    163 ALDAKVRKELRRWLRRlhDELGGTTVFVTHDQEEALELADRVVVMNQG 210
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
2275-2479 5.39e-25

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 106.27  E-value: 5.39e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSlgHVDSHSSLVGYCPQEDALDDLVTVEEH 2354
Cdd:cd03296     17 ALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDAT--DVPVQERNVGFVFQHYALFRHMTVFDN 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 LYFYARVHGI----PEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRH 2430
Cdd:cd03296     95 VAFGLRVKPRserpPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAKVRKE 174
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2431 L--W-KIISEEVqNKCSVILTsHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:cd03296    175 LrrWlRRLHDEL-HVTTVFVT-HDQEEALEVADRVVVMNKGRIEQVGTPDEV 224
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
2262-2479 8.64e-25

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 105.46  E-value: 8.64e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLIHKkiiAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK-TGSLGHVDSHSSLvGYCP 2340
Cdd:cd03295      6 VTKRYGGGKK---AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEdIREQDPVELRRKI-GYVI 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2341 QEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMP--FKDRATSMCSYGTKRKLSTALALIGKPSILLLDE 2418
Cdd:cd03295     82 QQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDPaeFADRYPHELSGGQQQRVGVARALAADPPLLLMDE 161
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 2419 PSSGMDPKSKRHL---WKIISEEVqNKcSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:cd03295    162 PFGALDPITRDQLqeeFKRLQQEL-GK-TIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEI 223
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
2276-2479 1.35e-24

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 104.98  E-value: 1.35e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSL-VGYCPQEDALDDLVTVEEH 2354
Cdd:PRK10895    19 VEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRgIGYLPQEASIFRRLSVYDN 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 LYFYARV-HGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWK 2433
Cdd:PRK10895    99 LMAVLQIrDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKR 178
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462571778 2434 IISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:PRK10895   179 IIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEI 224
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
2277-2480 1.44e-24

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 104.89  E-value: 1.44e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2277 NNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK-TGSLghvdSHSSL------VGYCPQEDALDDLV 2349
Cdd:cd03261     17 KGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEdISGL----SEAELyrlrrrMGMLFQSGALFDSL 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2350 TVEEHLYFYARVHGI-PEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSK 2428
Cdd:cd03261     93 TVFENVAFPLREHTRlSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLYDEPTAGLDPIAS 172
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2429 R---HLwkIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIK 2480
Cdd:cd03261    173 GvidDL--IRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELR 225
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
2276-2474 1.52e-24

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 102.90  E-value: 1.52e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSH--SSLVGYCPQedalddlvtvee 2353
Cdd:cd03214     15 LDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGK--DLASLSPKelARKIAYVPQ------------ 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 hlyfyarvhgipekdiketvhkLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWK 2433
Cdd:cd03214     81 ----------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQIELLE 138
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 2462571778 2434 IISEEVQNK-CSVILTSHSMEECEALCTRLAIMVNGKFQCIG 2474
Cdd:cd03214    139 LLRRLARERgKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
2262-2469 1.54e-24

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 102.65  E-value: 1.54e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK--TGSLGHVDSHSSLVGYC 2339
Cdd:cd03229      6 VSKRY----GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEdlTDLEDELPPLRRRIGMV 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2340 PQEDALddlvtveehlyfyarvhgIPEKDIKETVHKLLrrlhlmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEP 2419
Cdd:cd03229     82 FQDFAL------------------FPHLTVLENIALGL----------------SGGQQQRVALARALAMDPDVLLLDEP 127
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 2420 SSGMDPKSKRHLWKIISEEVQN-KCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03229    128 TSALDPITRREVRALLKSLQAQlGITVVLVTHDLDEAARLADRVVVLRDGK 178
cbiO PRK13637
energy-coupling factor transporter ATPase;
1353-1564 2.48e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 105.51  E-value: 2.48e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIY--GS---KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI---KTDLHTVRKNMG 1424
Cdd:PRK13637     7 NLTHIYmeGTpfeKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDItdkKVKLSDIRKKVG 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1425 VCMQHDVLFSYLTTKEHLLLYGSIKVpHWTKKQLHEEVKRTLKDTGL-YS-HRHKRVGTLSGGMKRKLSISIALIGGSRV 1502
Cdd:PRK13637    87 LVFQYPEYQLFEETIEKDIAFGPINL-GLSEEEIENRVKRAMNIVGLdYEdYKDKSPFELSGGQKRRVAIAGVVAMEPKI 165
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1503 VILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK13637   166 LILDEPTAGLDPKGRDEILNKIKElhKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTP 229
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
1363-1556 2.62e-24

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 105.20  E-value: 2.62e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-KTDLHTVRKNMGVCMQ--HDVLFSylTTK 1439
Cdd:PRK13647    20 ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVnAENEKWVRSKVGLVFQdpDDQVFS--STV 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1440 EHLLLYGSIKVpHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRS 1519
Cdd:PRK13647    98 WDDVAFGPVNM-GLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQET 176
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 2462571778 1520 IWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK13647   177 LMEILDRlHNQGKTVIVATHDVDLAAEWADQVIVLKEG 214
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
2257-2474 2.74e-24

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 103.10  E-value: 2.74e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2257 VQLYCLTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgslghvdshssLV 2336
Cdd:cd03301      1 VELENVTKRF----GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGR------------DV 64
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2337 GYCPQED----------ALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALA 2406
Cdd:cd03301     65 TDLPPKDrdiamvfqnyALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRA 144
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 2407 LIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQN-KCSVILTSHSMEECEALCTRLAIMVNGKFQCIG 2474
Cdd:cd03301    145 IVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRlGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
2270-2475 3.95e-24

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 103.62  E-value: 3.95e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2270 HKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSL---GhvdshsslVGYCPqedald 2346
Cdd:COG1134     36 REEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRVSALlelG--------AGFHP------ 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2347 DLvTVEEHLYFYARVHGIPEKDIKETVHK------LLRRLHlMPFKdratsMCSYGTKRKLSTALALIGKPSILLLDEPS 2420
Cdd:COG1134    102 EL-TGRENIYLNGRLLGLSRKEIDEKFDEivefaeLGDFID-QPVK-----TYSSGMRARLAFAVATAVDPDILLVDEVL 174
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 2421 SGMDP----KSKRHlwkiISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGS 2475
Cdd:COG1134    175 AVGDAafqkKCLAR----IRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGD 229
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
1353-1556 4.61e-24

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 103.92  E-value: 4.61e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIK--TDLHTVRKNMGVCMQHD 1430
Cdd:PRK11300    10 GLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEglPGHQIARMGVVRTFQHV 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSYLTTKEHLL-----------LYGSIKVPHWTKKQlHEEVKRT---LKDTGLYSHRHKRVGTLSGGMKRKLSISIAL 1496
Cdd:PRK11300    90 RLFREMTVIENLLvaqhqqlktglFSGLLKTPAFRRAE-SEALDRAatwLERVGLLEHANRQAGNLAYGQQRRLEIARCM 168
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1497 IGGSRVVILDEPSTGVDPCSRRSIWDVIS--KNKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK11300   169 VTQPEILMLDEPAAGLNPKETKELDELIAelRNEHNVTVLLIEHDMKLVMGISDRIYVVNQG 230
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
1364-1556 6.10e-24

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 102.93  E-value: 6.10e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1364 VDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKnmgVCMQHDVLFSYLTTKEHLL 1443
Cdd:TIGR01184    1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQI-TEPGPDRM---VVFQNYSLLPWLTVRENIA 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1444 LYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDV 1523
Cdd:TIGR01184   77 LAVDRVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEE 156
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2462571778 1524 ISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:TIGR01184  157 LMQiwEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
2270-2469 6.42e-24

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 102.51  E-value: 6.42e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2270 HKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSHSSL---VGYCPQEDALD 2346
Cdd:cd03224     10 YGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGR--DITGLPPHERAragIGYVPEGRRIF 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2347 DLVTVEEHL--YFYARVHGIPEKDIKEtVHKLLRRLHLMpFKDRATSMcSYGTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:cd03224     88 PELTVEENLllGAYARRRAKRKARLER-VYELFPRLKER-RKQLAGTL-SGGEQQMLAIARALMSRPKLLLLDEPSEGLA 164
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2462571778 2425 PKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03224    165 PKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGR 209
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
1338-1558 8.99e-24

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 101.09  E-value: 8.99e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1338 IEPEPKDLTVGVAlHGVTKiyGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGL--FGASAGTIFVYGKDIktD 1415
Cdd:cd03213      2 VTLSFRNLTVTVK-SSPSK--SGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRrtGLGVSGEVLINGRPL--D 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1416 LHTVRKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVphwtkkqlheevkrtlkdtglyshrhkrvgtLSGGMKRKLSISIA 1495
Cdd:cd03213     77 KRSFRKIIGYVPQDDILHPTLTVRETLMFAAKLRG-------------------------------LSGGERKRVSIALE 125
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1496 LIGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHL-DEAEVLSDRIAFLEQGGL 1558
Cdd:cd03213    126 LVSNPSLLFLDEPTSGLDSSSALQVMSLLRRlADTGRTIICSIHQPsSEIFELFDKLLLLSQGRV 190
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
2275-2469 9.83e-24

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 103.77  E-value: 9.83e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgslghVDShsSLVGYCPQEDALDDLVTVEEH 2354
Cdd:PRK13636    21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKP-----IDY--SRKGLMKLRESVGMVFQDPDN 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 LYFYARVH----------GIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:PRK13636    94 QLFSASVYqdvsfgavnlKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLD 173
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462571778 2425 PKSKRHLWKIISEEVQN-KCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK13636   174 PMGVSEIMKLLVEMQKElGLTIIIATHDIDIVPLYCDNVFVMKEGR 219
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
1349-1556 9.84e-24

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 102.57  E-value: 9.84e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSK----VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-KTDLHTVRKNM 1423
Cdd:COG1124      2 LEVRNLSVSYGQGgrrvPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVtRRRRKAFRRRV 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1424 GVCMQHDvlfsylttkehlllYGSIKvPHWT-KKQLHE------------EVKRTLKDTGLY-SHRHKRVGTLSGGMKRK 1489
Cdd:COG1124     82 QMVFQDP--------------YASLH-PRHTvDRILAEplrihglpdreeRIAELLEQVGLPpSFLDRYPHQLSGGQRQR 146
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1490 LSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTAR--TIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:COG1124    147 VAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERglTYLFVSHDLAVVAHLCDRVAVMQNG 215
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
2262-2469 1.00e-23

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 101.80  E-value: 1.00e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI----------------RNKTgs 2325
Cdd:cd03255      6 LSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVdgtdisklsekelaafRRRH-- 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2326 lghvdshsslVGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLmpfKDRATSMC---SYGTKRKLS 2402
Cdd:cd03255     84 ----------IGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGL---GDRLNHYPselSGGQQQRVA 150
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2403 TALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNK-CSVILTSHSMEEcEALCTRLAIMVNGK 2469
Cdd:cd03255    151 IARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAgTTIVVVTHDPEL-AEYADRIIELRDGK 217
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
1349-1556 1.01e-23

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 102.05  E-value: 1.01e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIY-GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT----DLHTVRKNM 1423
Cdd:COG2884      2 IRFENVSKRYpGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRlkrrEIPYLRRRI 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1424 GVCMQhDV-LFSYLTTKEHLLLygSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRV 1502
Cdd:COG2884     82 GVVFQ-DFrLLPDRTVYENVAL--PLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPEL 158
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1503 VILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:COG2884    159 LLADEPTGNLDPETSWEIMELLEEiNRRGTTVLIATHDLELVDRMPKRVLELEDG 213
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
1349-1544 1.83e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 109.06  E-value: 1.83e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVR-------- 1420
Cdd:NF033858     2 ARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRRAvcpriaym 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1421 -----KNmgvcmqhdvLFSYLTTKEHLL----LYGsikvpHwTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLS 1491
Cdd:NF033858    82 pqglgKN---------LYPTLSVFENLDffgrLFG-----Q-DAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLG 146
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 1492 ISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTAR---TIILSTHHLDEAE 1544
Cdd:NF033858   147 LCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERpgmSVLVATAYMEEAE 202
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
1349-1556 2.68e-23

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 103.62  E-value: 2.68e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSK----VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT----DLHTVR 1420
Cdd:COG1135      2 IELENLSKTFPTKggpvTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTAlserELRAAR 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1421 KNMGVCMQHDVLFSYLTTkehlllYGSI----KVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIAL 1496
Cdd:COG1135     82 RKIGMIFQHFNLLSSRTV------AENValplEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARAL 155
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1497 IGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTAR-TIILSTHhldEAEV---LSDRIAFLEQG 1556
Cdd:COG1135    156 ANNPKVLLCDEATSALDPETTRSILDLLKDiNRELGlTIVLITH---EMDVvrrICDRVAVLENG 217
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
1351-1564 2.71e-23

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 101.70  E-value: 2.71e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-KTDLHTVRKNMGVCMQH 1429
Cdd:COG4604      4 IKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVaTTPSRELAKRLAILRQE 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYLTTKEhLLLYGsiKVPHwTKKQL----HEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVIL 1505
Cdd:COG4604     84 NHINSRLTVRE-LVAFG--RFPY-SKGRLtaedREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLL 159
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1506 DEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:COG4604    160 DEPLNNLDMKHSVQMMKLLRRlaDELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTP 220
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
1363-1573 2.76e-23

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 102.62  E-value: 2.76e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI---KTDLHTVRKNMGVCMQH--DVLFSYLT 1437
Cdd:PRK13636    21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIdysRKGLMKLRESVGMVFQDpdNQLFSASV 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1438 TKEhlLLYG--SIKVPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPC 1515
Cdd:PRK13636   101 YQD--VSFGavNLKLP---EDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPM 175
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1516 SRRSIWDVI--SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPfylKEAFGD 1573
Cdd:PRK13636   176 GVSEIMKLLveMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNP---KEVFAE 232
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1349-1564 4.49e-23

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 103.87  E-value: 4.49e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI------KTDLHTVrkn 1422
Cdd:PRK09452    15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDIthvpaeNRHVNTV--- 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1423 mgvcMQHDVLFSYLTTKEHlLLYG--SIKVPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGS 1500
Cdd:PRK09452    92 ----FQSYALFPHMTVFEN-VAFGlrMQKTP---AAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKP 163
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 1501 RVVILDEPSTGVDPCSRRSIWDVIS--KNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK09452   164 KVLLLDESLSALDYKLRKQMQNELKalQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTP 229
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
1363-1558 5.06e-23

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 99.97  E-value: 5.06e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFsYLTTKEH 1441
Cdd:cd03245     19 ALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQlDPADLRRNIGYVPQDVTLF-YGTLRDN 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1442 LLLygsiKVPHWTKkqlhEEVKRTLKDTGL--YSHRHKR-----VG----TLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:cd03245     98 ITL----GAPLADD----ERILRAAELAGVtdFVNKHPNgldlqIGergrGLSGGQRQAVALARALLNDPPILLLDEPTS 169
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1511 GVDPCSRRSIWDVISKNKTARTIILSTHH---LDeaevLSDRIAFLEQGGL 1558
Cdd:cd03245    170 AMDMNSEERLKERLRQLLGDKTLIIITHRpslLD----LVDRIIVMDSGRI 216
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
1354-1564 5.87e-23

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 100.35  E-value: 5.87e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1354 VTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHT-VRKNMGVCMQHDV 1431
Cdd:PRK10895     9 LAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLlPLHArARRGIGYLPQEAS 88
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1432 LFSYLTTKEHLLLYGSIKvPHWTKKQLHEEVKRTLKDTGLySHRHKRVG-TLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:PRK10895    89 IFRRLSVYDNLMAVLQIR-DDLSAEQREDRANELMEEFHI-EHLRDSMGqSLSGGERRRVEIARALAANPKFILLDEPFA 166
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1511 GVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK10895   167 GVDPISVIDIKRIIEHlRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTP 221
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
1349-1564 8.60e-23

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 99.78  E-value: 8.60e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYG---KDIKTDLHTVRKNMGV 1425
Cdd:PRK09493     2 IEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGlkvNDPKVDERLIRQEAGM 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1426 CMQHDVLFSYLTTKEHlLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVIL 1505
Cdd:PRK09493    82 VFQQFYLFPHLTALEN-VMFGPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLF 160
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1506 DEPSTGVDPCSRRSIWDVI-SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK09493   161 DEPTSALDPELRHEVLKVMqDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDP 220
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
2256-2479 1.35e-22

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 102.33  E-value: 1.35e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2256 LVQLYCLTKTYQliHKKIIavNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgsLGHVDSHSSL 2335
Cdd:PRK09452    14 LVELRGISKSFD--GKEVI--SNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQD--ITHVPAENRH 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2336 VGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILL 2415
Cdd:PRK09452    88 VNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLL 167
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 2416 LDEPSSGMDPKskrhLWKIISEEV---QNKCSV--ILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:PRK09452   168 LDESLSALDYK----LRKQMQNELkalQRKLGItfVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREI 232
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
1349-1564 2.51e-22

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 101.33  E-value: 2.51e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKtdlHTVRKNMGVCM- 1427
Cdd:PRK11432     7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVT---HRSIQQRDICMv 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 -QHDVLFSYLTTKEHlLLYGsIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILD 1506
Cdd:PRK11432    84 fQSYALFPHMSLGEN-VGYG-LKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFD 161
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1507 EPSTGVDPCSRRSIWDVISKNKTARTI--ILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK11432   162 EPLSNLDANLRRSMREKIRELQQQFNItsLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSP 221
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
1354-1556 2.60e-22

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 97.48  E-value: 2.60e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1354 VTKIYGSKV-AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHT-----VRKNMGVCM 1427
Cdd:cd03292      6 VTKTYPNGTaALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDV-SDLRGraipyLRRKIGVVF 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QHDVLFSYLTTKEHLLLygSIKVPHWTKKQLHEEVKRTLKDTGLySHRHKRVGT-LSGGMKRKLSISIALIGGSRVVILD 1506
Cdd:cd03292     85 QDFRLLPDRNVYENVAF--ALEVTGVPPREIRKRVPAALELVGL-SHKHRALPAeLSGGEQQRVAIARAIVNSPTILIAD 161
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1507 EPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03292    162 EPTGNLDPDTTWEIMNLLKKiNKAGTTVVVATHAKELVDTTRHRVIALERG 212
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
2273-2481 3.07e-22

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 98.52  E-value: 3.07e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2273 IIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK--TGSLGHVDSHSSLVGYCPQEDALDDLVT 2350
Cdd:PRK11300    18 LLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQhiEGLPGHQIARMGVVRTFQHVRLFREMTV 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2351 VE-----EHLYFYARV-HGI--------PEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLL 2416
Cdd:PRK11300    98 IEnllvaQHQQLKTGLfSGLlktpafrrAESEALDRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILML 177
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 2417 DEPSSGMDPKSKRHLWKIISE-EVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKS 2481
Cdd:PRK11300   178 DEPAAGLNPKETKELDELIAElRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIRN 243
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
2276-2469 3.48e-22

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 96.47  E-value: 3.48e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPS--SGNILIRNKTGSLghvDSHSSLVGYCPQEDALDDLVTVEE 2353
Cdd:cd03213     25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLgvSGEVLINGRPLDK---RSFRKIIGYVPQDDILHPTLTVRE 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 HLYFYARVHGIpekdiketvhkllrrlhlmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWK 2433
Cdd:cd03213    102 TLMFAAKLRGL-----------------------------SGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMS 152
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2462571778 2434 IISEEVQNKCSVILTSHSM-EECEALCTRLAIMVNGK 2469
Cdd:cd03213    153 LLRRLADTGRTIICSIHQPsSEIFELFDKLLLLSQGR 189
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1361-1556 4.42e-22

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 99.78  E-value: 4.42e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1361 KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCM-QHDVLFSYLTTK 1439
Cdd:COG4586     35 VEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYVPFKRRKEFARRIGVVFgQRSQLWWDLPAI 114
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1440 EHLLLYGSI-KVPHWTKKQLHEEVKRTLKDTGLYshrHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRR 1518
Cdd:COG4586    115 DSFRLLKAIyRIPDAEYKKRLDELVELLDLGELL---DTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKE 191
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2462571778 1519 SIWDVISK-NKTAR-TIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:COG4586    192 AIREFLKEyNRERGtTILLTSHDMDDIEALCDRVIVIDHG 231
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
1358-1558 4.86e-22

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 97.92  E-value: 4.86e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTT---TISMLTGLFG--ASAGTIFVYGKDI---KTDLHTVRKNMGVCMQH 1429
Cdd:PRK14239    15 YNKKKALNSVSLDFYPNEITALIGPSGSGKSTllrSINRMNDLNPevTITGSIVYNGHNIyspRTDTVDLRKEIGMVFQQ 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSyLTTKEHLLlYG----SIKvphwTKKQLHEEVKRTLKDTGLYS----HRHKRVGTLSGGMKRKLSISIALIGGSR 1501
Cdd:PRK14239    95 PNPFP-MSIYENVV-YGlrlkGIK----DKQVLDEAVEKSLKGASIWDevkdRLHDSALGLSGGQQQRVCIARVLATSPK 168
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1502 VVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGL 1558
Cdd:PRK14239   169 IILLDEPTSALDPISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDL 225
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
2269-2474 6.35e-22

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 96.60  E-value: 6.35e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2269 IHKKIIAVN-NISIGIPaGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI--------RNKTgslgHVDSHSSLVGYC 2339
Cdd:cd03297      6 IEKRLPDFTlKIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLngtvlfdsRKKI----NLPPQQRKIGLV 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2340 PQEDALDDLVTVEEHLYFYARVHgiPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEP 2419
Cdd:cd03297     81 FQQYALFPHLNVRENLAFGLKRK--RNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEP 158
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 2420 SSGMDPKSKRHLWKIISEEVQN-KCSVILTSHSMEECEALCTRLAIMVNGKFQCIG 2474
Cdd:cd03297    159 FSALDRALRLQLLPELKQIKKNlNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
1349-1550 8.84e-22

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 101.63  E-value: 8.84e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKtdLHTVR--KNMGVC 1426
Cdd:COG1129      5 LEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVR--FRSPRdaQAAGIA 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 M--QHDVLFSYLTTKEHLLL------YGSIKvphwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIG 1498
Cdd:COG1129     83 IihQELNLVPNLSVAENIFLgreprrGGLID-----WRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSR 157
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1499 GSRVVILDEPSTGVDPCSRRSIWDVISKNKTA-RTIILSTHHLDEAEVLSDRI 1550
Cdd:COG1129    158 DARVLILDEPTASLTEREVERLFRIIRRLKAQgVAIIYISHRLDEVFEIADRV 210
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
2272-2469 1.20e-21

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 96.20  E-value: 1.20e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2272 KIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSHSSL---VGYCPQEDAL-DD 2347
Cdd:COG0410     15 GIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGE--DITGLPPHRIArlgIGYVPEGRRIfPS 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2348 LvTVEEHLY--FYARVHGIPEKDIKETVHKLLRRLHLMpFKDRATSMcSYGTKRKLSTALALIGKPSILLLDEPSSGMDP 2425
Cdd:COG0410     93 L-TVEENLLlgAYARRDRAEVRADLERVYELFPRLKER-RRQRAGTL-SGGEQQMLAIGRALMSRPKLLLLDEPSLGLAP 169
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 2462571778 2426 KSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:COG0410    170 LIVEEIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGR 213
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
1358-1556 1.20e-21

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 96.14  E-value: 1.20e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKV-AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSY 1435
Cdd:cd03254     12 YDEKKpVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDiSRKSLRSMIGVVLQDTFLFSG 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 lTTKEHLLLYGSI----KVPHWTK-KQLHEEVKRtLKDtGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:cd03254     92 -TIMENIRLGRPNatdeEVIEAAKeAGAHDFIMK-LPN-GYDTVLGENGGNLSQGERQLLAIARAMLRDPKILILDEATS 168
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462571778 1511 GVDPCSRRSIWDVISKNKTARTIILSTHHLDEAeVLSDRIAFLEQG 1556
Cdd:cd03254    169 NIDTETEKLIQEALEKLMKGRTSIIIAHRLSTI-KNADKILVLDDG 213
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
2271-2469 1.28e-21

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 95.80  E-value: 1.28e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2271 KKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPS---SGNILIRNKTGSLGHVDSHsslVGYCPQEDALDD 2347
Cdd:cd03234     18 KYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGgttSGQILFNGQPRKPDQFQKC---VAYVRQDDILLP 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2348 LVTVEEHLYFYARVHGiPEK-----DIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSG 2422
Cdd:cd03234     95 GLTVRETLTYTAILRL-PRKssdaiRKKRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSG 173
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 2423 MDPKSKRHLWKIISEEVQNKCSVILTSHS-MEECEALCTRLAIMVNGK 2469
Cdd:cd03234    174 LDSFTALNLVSTLSQLARRNRIVILTIHQpRSDLFRLFDRILLLSSGE 221
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
1367-1556 1.29e-21

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 95.64  E-value: 1.29e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1367 LNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGVCMQHDVLFSYLTTKEHLLLyG 1446
Cdd:cd03298     17 FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDV-TAAPPADRPVSMLFQENNLFAHLTVEQNVGL-G 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1447 SIKVPHWTKKQlHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK 1526
Cdd:cd03298     95 LSPGLKLTAED-RQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLD 173
                          170       180       190
                   ....*....|....*....|....*....|..
gi 2462571778 1527 --NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03298    174 lhAETKMTVLMVTHQPEDAKRLAQRVVFLDNG 205
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
1360-1585 1.42e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 96.98  E-value: 1.42e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1360 SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTD-LHTVRKNMGVCMQH-DVLFSYLT 1437
Cdd:PRK13632    21 ENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKEnLKEIRKKIGIIFQNpDNQFIGAT 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1438 TKEHlLLYG--SIKVPHWTKKQLHEEVKrtlKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPC 1515
Cdd:PRK13632   101 VEDD-IAFGleNKKVPPKKMKDIIDDLA---KKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPK 176
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1516 SRRSIWDVIS--KNKTARTIILSTHHLDEAeVLSDRIAFLEQGGLRCCGSPfylKEAFGDGYHLTLTKKKSP 1585
Cdd:PRK13632   177 GKREIKKIMVdlRKTRKKTLISITHDMDEA-ILADKVIVFSEGKLIAQGKP---KEILNNKEILEKAKIDSP 244
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
1358-1558 1.45e-21

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 96.25  E-value: 1.45e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCM-QHDVLFSYL 1436
Cdd:cd03267     31 YREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKFLRRIGVVFgQKTQLWWDL 110
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1437 TTKEHLLLYGSI-KVPHWTKKQLHEEVKRTLKDTGLYshrHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPC 1515
Cdd:cd03267    111 PVIDSFYLLAAIyDLPPARFKKRLDELSELLDLEELL---DTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVV 187
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2462571778 1516 SRRSIWDVISK-NK-TARTIILSTHHLDEAEVLSDRIAFLEQGGL 1558
Cdd:cd03267    188 AQENIRNFLKEyNReRGTTVLLTSHYMKDIEALARRVLVIDKGRL 232
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
2275-2469 2.01e-21

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 102.22  E-value: 2.01e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSHS--SLVGYCPQEDAL-DDlvTV 2351
Cdd:COG2274    490 VLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGI--DLRQIDPASlrRQIGVVLQDVFLfSG--TI 565
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 EEHLYFYARvhGIPEKDIKET-----VHKLLRRLHL---MPFKDRATSMcSYGTKRKLSTALALIGKPSILLLDEPSSGM 2423
Cdd:COG2274    566 RENITLGDP--DATDEEIIEAarlagLHDFIEALPMgydTVVGEGGSNL-SGGQRQRLAIARALLRNPRILILDEATSAL 642
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462571778 2424 DPKSKRHLWKIISEEVQNkCSVILTSHSMeECEALCTRLAIMVNGK 2469
Cdd:COG2274    643 DAETEAIILENLRRLLKG-RTVIIIAHRL-STIRLADRIIVLDKGR 686
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
1360-1571 2.04e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 96.70  E-value: 2.04e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1360 SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHT--VRKNMGVCMQH-------- 1429
Cdd:PRK13633    22 EKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENLwdIRNKAGMVFQNpdnqivat 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 ----DVLFSylttKEHLllygsiKVPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVIL 1505
Cdd:PRK13633   102 iveeDVAFG----PENL------GIP---PEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIF 168
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1506 DEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAeVLSDRIAFLEQGGLRCCGSPfylKEAF 1571
Cdd:PRK13633   169 DEPTAMLDPSGRREVVNTIKElnKKYGITIILITHYMEEA-VEADRIIVMDSGKVVMEGTP---KEIF 232
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
2262-2465 2.35e-21

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 95.19  E-value: 2.35e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLIH---KKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGS--LGHVDSHSSL- 2335
Cdd:COG4778     10 LSKTFTLHLqggKRLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGGWvdLAQASPREILa 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2336 -----VGYC-------PQEDALDdlvTVEEHLyfyaRVHGIPEKDIKETVHKLLRRL-------HLMPfkdrATSmcSYG 2396
Cdd:COG4778     90 lrrrtIGYVsqflrviPRVSALD---VVAEPL----LERGVDREEARARARELLARLnlperlwDLPP----ATF--SGG 156
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 2397 TKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIM 2465
Cdd:COG4778    157 EQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGIFHDEEVREAVADRVVDV 225
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
1358-1564 2.35e-21

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 95.85  E-value: 2.35e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTdlHTVR---KNMGVCMQHDVLFS 1434
Cdd:PRK11231    12 YGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISM--LSSRqlaRRLALLPQHHLTPE 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1435 YLTTKEhLLLYG-SIKVPHWTK--KQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTG 1511
Cdd:PRK11231    90 GITVRE-LVAYGrSPWLSLWGRlsAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTY 168
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1512 VDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK11231   169 LDINHQVELMRLMRElNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTP 222
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
2275-2469 2.35e-21

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 93.22  E-value: 2.35e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSHS--SLVGYCPQEDAL-DDlvTV 2351
Cdd:cd03228     17 VLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGV--DLRDLDLESlrKNIAYVPQDPFLfSG--TI 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 EEHLYfyarvhgipekdiketvhkllrrlhlmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHL 2431
Cdd:cd03228     93 RENIL-------------------------------------SGGQRQRIAIARALLRDPPILILDEATSALDPETEALI 135
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 2462571778 2432 WKIISEEVQNKcSVILTSHSMEECEaLCTRLAIMVNGK 2469
Cdd:cd03228    136 LEALRALAKGK-TVIVIAHRLSTIR-DADRIIVLDDGR 171
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
1363-1578 2.80e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 96.36  E-value: 2.80e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQ------------H 1429
Cdd:PRK13648    24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDdNFEKLRKHIGIVFQnpdnqfvgsivkY 103
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYlttKEHLllygsikVPHwtkKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPS 1509
Cdd:PRK13648   104 DVAFGL---ENHA-------VPY---DEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEAT 170
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1510 TGVDPCSRRSIWDVISKNKTAR--TIILSTHHLDEAeVLSDRIAFLEQGGLRCCGSPfylKEAFGDGYHLT 1578
Cdd:PRK13648   171 SMLDPDARQNLLDLVRKVKSEHniTIISITHDLSEA-MEADHVIVMNKGTVYKEGTP---TEIFDHAEELT 237
cbiO PRK13650
energy-coupling factor transporter ATPase;
2276-2486 3.87e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 95.95  E-value: 3.87e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQeDALDDLV--TVEE 2353
Cdd:PRK13650    23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDIRHKIGMVFQ-NPDNQFVgaTVED 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 HLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWK 2433
Cdd:PRK13650   102 DVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIK 181
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 2434 IISE-EVQNKCSVILTSHSMEECeALCTRLAIMVNGKFQCIGSLQHIksrFGRG 2486
Cdd:PRK13650   182 TIKGiRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPREL---FSRG 231
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
2256-2479 3.90e-21

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 99.86  E-value: 3.90e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2256 LVQLYCLTKTYQLIHkkiiAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGS-LGHVDSHSS 2334
Cdd:PRK09700     5 YISMAGIGKSFGPVH----ALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNkLDHKLAAQL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2335 LVGYCPQEDALDDLVTVEEHLYF----YARVHGIPEKDIKETVHK---LLRRLHLMPFKDRATSMCSYGTKRKLSTALAL 2407
Cdd:PRK09700    81 GIGIIYQELSVIDELTVLENLYIgrhlTKKVCGVNIIDWREMRVRaamMLLRVGLKVDLDEKVANLSISHKQMLEIAKTL 160
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2408 IGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:PRK09700   161 MLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDV 232
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
1358-1558 3.97e-21

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 95.49  E-value: 3.97e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLF----GASA-GTIFVYGKDI---KTDLHTVRKNMGVCMQH 1429
Cdd:COG1117     21 YGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNdlipGARVeGEILLDGEDIydpDVDVVELRRRVGMVFQK 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLF--------SYLttkehLLLYGsIKvphwTKKQLHEEVKRTLKDTGLY---SHR-HKRVGTLSGGMKRKLSISIALI 1497
Cdd:COG1117    101 PNPFpksiydnvAYG-----LRLHG-IK----SKSELDEIVEESLRKAALWdevKDRlKKSALGLSGGQQQRLCIARALA 170
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1498 GGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGL 1558
Cdd:COG1117    171 VEPEVLLMDEPTSALDPISTAKIEELILELKKDYTIVIVTHNMQQAARVSDYTAFFYLGEL 231
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
1354-1556 5.01e-21

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 95.46  E-value: 5.01e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1354 VTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLF---GASAGTIFVYGKDIKT------DLHTVRKNMG 1424
Cdd:PRK09984    10 LAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLItgdKSAGSHIELLGRTVQRegrlarDIRKSRANTG 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1425 VCMQHDVLFSYLTTKEHLLLYGSIKVPHWT------KKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIG 1498
Cdd:PRK09984    90 YIFQQFNLVNRLSVLENVLIGALGSTPFWRtcfswfTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAIARALMQ 169
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1499 GSRVVILDEPSTGVDPCSRRSIWDVISK-NKT-ARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK09984   170 QAKVILADEPIASLDPESARIVMDTLRDiNQNdGITVVVTLHQVDYALRYCERIVALRQG 229
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
1359-1599 5.51e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 95.64  E-value: 5.51e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1359 GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-KTDLHTVRKNMGVCMQH--DVLFSy 1435
Cdd:PRK13652    15 GSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPItKENIREVRKFVGLVFQNpdDQIFS- 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 lTTKEHLLLYGSIKVPHWTKKQLHEeVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPC 1515
Cdd:PRK13652    94 -PTVEQDIAFGPINLGLDEETVAHR-VSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQ 171
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1516 SRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP--FYLKEAFGDGYHLTL--TKKKSPNLNA 1589
Cdd:PRK13652   172 GVKELIDFLNDlpETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVeeIFLQPDLLARVHLDLpsLPKLIRSLQA 251
                          250
                   ....*....|
gi 2462571778 1590 NAVCDTMAVT 1599
Cdd:PRK13652   252 QGIAIDMAYT 261
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
2272-2491 8.00e-21

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 96.73  E-value: 8.00e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2272 KIIAVNNISIGIPAGECFGLLGVNGAG--KTTIFKMLTGdiiPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDDLV 2349
Cdd:NF000106    25 EVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGRRPWRF*TWCANRRALRRTIG*HRPVR*GRRESF 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2350 TVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKR 2429
Cdd:NF000106   102 SGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRN 181
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2430 HLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKSRFGrGFTVKV 2491
Cdd:NF000106   182 EVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG-GRTLQI 242
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
1311-1556 1.17e-20

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 99.08  E-value: 1.17e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1311 LMFTNIMMQNTNPSASK-----TSPEYMFSSNIEPEPKDLTVGVALHGVTKIY-GSKVAVDNLNLNFYEGHITSLLGPNG 1384
Cdd:COG1132    297 LANVLNQLQRALASAERifellDEPPEIPDPPGAVPLPPVRGEIEFENVSFSYpGDRPVLKDISLTIPPGETVALVGPSG 376
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1385 AGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSyLTTKEHlLLYGSIKVPhwtkkqlHEEVK 1463
Cdd:COG1132    377 SGKSTLVNLLLRFYDPTSGRILIDGVDIRDlTLESLRRQIGVVPQDTFLFS-GTIREN-IRYGRPDAT-------DEEVE 447
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1464 RTLKDTGL----------YSHrhkRVG----TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKT 1529
Cdd:COG1132    448 EAAKAAQAhefiealpdgYDT---VVGergvNLSGGQRQRIAIARALLKDPPILILDEATSALDTETEALIQEALERLMK 524
                          250       260
                   ....*....|....*....|....*..
gi 2462571778 1530 ARTIILSTHHLDEAEvLSDRIAFLEQG 1556
Cdd:COG1132    525 GRTTIVIAHRLSTIR-NADRILVLDDG 550
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
2271-2469 1.79e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 94.00  E-value: 1.79e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2271 KKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRN----KTGSLGHVDSHSSLVGYCPQedalD 2346
Cdd:PRK13633    21 TEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGldtsDEENLWDIRNKAGMVFQNPD----N 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2347 DLVT--VEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:PRK13633    97 QIVAtiVEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLD 176
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 2425 PKSKRHLWKIISEevQNK---CSVILTSHSMEECeALCTRLAIMVNGK 2469
Cdd:PRK13633   177 PSGRREVVNTIKE--LNKkygITIILITHYMEEA-VEADRIIVMDSGK 221
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
1351-1556 2.26e-20

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 92.51  E-value: 2.26e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAvdNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGVCMQHD 1430
Cdd:COG3840      4 LDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDL-TALPPAERPVSMLFQEN 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSYLTTKEHLLLyG---SIKVphwTKKQlHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDE 1507
Cdd:COG3840     81 NLFPHLTVAQNIGL-GlrpGLKL---TAEQ-RAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDE 155
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1508 PSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:COG3840    156 PFSALDPALRQEMLDLVDElcRERGLTVLMVTHDPEDAARIADRVLLVADG 206
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
2275-2482 2.62e-20

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 93.71  E-value: 2.62e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDalDDLV---TV 2351
Cdd:PRK13652    19 ALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKFVGLVFQNP--DDQIfspTV 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 EEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHL 2431
Cdd:PRK13652    97 EQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKEL 176
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2432 WKIISEEVQN-KCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKSR 2482
Cdd:PRK13652   177 IDFLNDLPETyGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQ 228
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
1349-1556 4.94e-20

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 89.68  E-value: 4.94e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYG--SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVC 1426
Cdd:cd03247      1 LSINNVSFSYPeqEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSLISVL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 MQHDVLFsylttkehlllygsikvphwtkkqlheevkrtlkDTGLYSHRHKRvgtLSGGMKRKLSISIALIGGSRVVILD 1506
Cdd:cd03247     81 NQRPYLF----------------------------------DTTLRNNLGRR---FSGGERQRLALARILLQDAPIVLLD 123
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1507 EPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLsDRIAFLEQG 1556
Cdd:cd03247    124 EPTVGLDPITERQLLSLIFEVLKDKTLIWITHHLTGIEHM-DKILFLENG 172
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
1358-1558 7.57e-20

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 91.44  E-value: 7.57e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLF-----GASAGTIFVYGKDI---KTDLHTVRKNMGVCMQH 1429
Cdd:PRK14267    14 YGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLelneeARVEGEVRLFGRNIyspDVDPIEVRREVGMVFQY 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRV----GTLSGGMKRKLSISIALIGGSRVVIL 1505
Cdd:PRK14267    94 PNPFPHLTIYDNVAIGVKLNGLVKSKKELDERVEWALKKAALWDEVKDRLndypSNLSGGQRQRLVIARALAMKPKILLM 173
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1506 DEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGL 1558
Cdd:PRK14267   174 DEPTANIDPVGTAKIEELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKL 226
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
2277-2483 9.01e-20

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 93.61  E-value: 9.01e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2277 NNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIliRNKTGSLGHVDSHSSLVGYCPQEDALDDLVTVEEHLY 2356
Cdd:PRK10851    19 NDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHI--RFHGTDVSRLHARDRKVGFVFQHYALFRHMTVFDNIA 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2357 FYARVhgIPEKD------IKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRH 2430
Cdd:PRK10851    97 FGLTV--LPRRErpnaaaIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRKE 174
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2431 L--W-KIISEEVqnKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI----KSRF 2483
Cdd:PRK10851   175 LrrWlRQLHEEL--KFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVwrepATRF 232
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
2262-2419 1.19e-19

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 95.52  E-value: 1.19e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQliHKKIIavNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGslghvdshsslVGYCPQ 2341
Cdd:COG0488      4 LSKSFG--GRPLL--DDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGLR-----------IGYLPQ 68
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLVTV----------------------------EEHLYFYARVHGIPEK----DIKETVHKLLRRLHLMPFK-DR 2388
Cdd:COG0488     69 EPPLDDDLTVldtvldgdaelraleaeleeleaklaepDEDLERLAELQEEFEAlggwEAEARAEEILSGLGFPEEDlDR 148
                          170       180       190
                   ....*....|....*....|....*....|.
gi 2462571778 2389 ATSMCSYGTKRKLSTALALIGKPSILLLDEP 2419
Cdd:COG0488    149 PVSELSGGWRRRVALARALLSEPDLLLLDEP 179
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
1361-1563 1.21e-19

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 91.26  E-value: 1.21e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1361 KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFG------ASAGTIFVYGKDI-KTDLHTVRKNMGVCMQHDVLF 1433
Cdd:PRK14246    23 KAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiydskiKVDGKVLYFGKDIfQIDAIKLRKEVGMVFQQPNPF 102
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1434 SylttkeHLLLYGSIKVPHWT-----KKQLHEEVKRTLKDTGLYSHRHKRVGT----LSGGMKRKLSISIALIGGSRVVI 1504
Cdd:PRK14246   103 P------HLSIYDNIAYPLKShgikeKREIKKIVEECLRKVGLWKEVYDRLNSpasqLSGGQQQRLTIARALALKPKVLL 176
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGS 1563
Cdd:PRK14246   177 MDEPTSMIDIVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGS 235
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
2275-2469 1.95e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 90.91  E-value: 1.95e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKT-----GSLGHVDSHSSLVGYCPqedalDDLV 2349
Cdd:PRK13639    17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPikydkKSLLEVRKTVGIVFQNP-----DDQL 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2350 ---TVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPK 2426
Cdd:PRK13639    92 fapTVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPM 171
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 2462571778 2427 SKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK13639   172 GASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGK 214
cbiO PRK13644
energy-coupling factor transporter ATPase;
1363-1564 2.01e-19

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 90.82  E-value: 2.01e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIK--TDLHTVRKNMGVCMQHDVLFSYLTTKE 1440
Cdd:PRK13644    17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGdfSKLQGIRKLVGIVFQNPETQFVGRTVE 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1441 HLLLYG--SIKVPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRR 1518
Cdd:PRK13644    97 EDLAFGpeNLCLP---PIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGI 173
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2462571778 1519 SIWDVISK-NKTARTIILSTHHLDEAEVlSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK13644   174 AVLERIKKlHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGEP 219
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
1366-1559 2.26e-19

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 88.89  E-value: 2.26e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1366 NLNLNF-YEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGK-----DIKTDLHTVRKNMGVCMQHDVLFSYLTTK 1439
Cdd:cd03297     14 TLKIDFdLNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTvlfdsRKKINLPPQQRKIGLVFQQYALFPHLNVR 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1440 EHLLlYGSIKVPHWTKKQLHEEVKRTLKDTGLyshRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRS 1519
Cdd:cd03297     94 ENLA-FGLKRKRNREDRISVDELLDLLGLDHL---LNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQ 169
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 2462571778 1520 IWDVISKNKTARTI--ILSTHHLDEAEVLSDRIAFLEQGGLR 1559
Cdd:cd03297    170 LLPELKQIKKNLNIpvIFVTHDLSEAEYLADRIVVMEDGRLQ 211
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
2275-2479 2.64e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 90.44  E-value: 2.64e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDalDDL---VTV 2351
Cdd:PRK13632    24 ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEIRKKIGIIFQNP--DNQfigATV 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 EEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHL 2431
Cdd:PRK13632   102 EDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREI 181
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2432 WKIISE--EVQNKCsVILTSHSMEECeALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:PRK13632   182 KKIMVDlrKTRKKT-LISITHDMDEA-ILADKVIVFSEGKLIAQGKPKEI 229
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
2262-2469 3.07e-19

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 91.79  E-value: 3.07e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI--RNKTG-----------SLGH 2328
Cdd:PRK11153     7 ISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVdgQDLTAlsekelrkarrQIGM 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2329 VDSH----SSLvgycpqedalddlvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTA 2404
Cdd:PRK11153    87 IFQHfnllSSR--------------TVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIA 152
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2405 LALIGKPSILLLDEPSSGMDPKSKR---HLWKIISEEVqnKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK11153   153 RALASNPKVLLCDEATSALDPATTRsilELLKDINREL--GLTIVLITHEMDVVKRICDRVAVIDAGR 218
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
2263-2469 4.50e-19

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 88.23  E-value: 4.50e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2263 TKTYQlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSL---VGYC 2339
Cdd:cd03292      7 TKTYP---NGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLrrkIGVV 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2340 PQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEP 2419
Cdd:cd03292     84 FQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEP 163
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2420 SSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03292    164 TGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGK 213
COG4674 COG4674
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1350-1511 5.07e-19

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443710 [Multi-domain]  Cd Length: 250  Bit Score: 89.02  E-value: 5.07e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1350 ALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-KTDLHTVrKNMGVC-- 1426
Cdd:COG4674     12 YVEDLTVSFDGFKALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLtGLDEHEI-ARLGIGrk 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 MQHDVLFSYLTTKEHLLL--------YGSIKvpHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIG 1498
Cdd:COG4674     91 FQKPTVFEELTVFENLELalkgdrgvFASLF--ARLTAEERDRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIGMLLAQ 168
                          170
                   ....*....|...
gi 2462571778 1499 GSRVVILDEPSTG 1511
Cdd:COG4674    169 DPKLLLLDEPVAG 181
cbiO PRK13645
energy-coupling factor transporter ATPase;
1344-1587 5.17e-19

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 90.07  E-value: 5.17e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1344 DLTVGVALHGVTKIYGSKV-----AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHT 1418
Cdd:PRK13645     2 DFSKDIILDNVSYTYAKKTpfefkALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIPANLKK 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1419 V------RKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHwTKKQLHEEVKRTLKDTGLYSHRHKRVG-TLSGGMKRKLS 1491
Cdd:PRK13645    82 IkevkrlRKEIGLVFQFPEYQLFQETIEKDIAFGPVNLGE-NKQEAYKKVPELLKLVQLPEDYVKRSPfELSGGQKRRVA 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1492 ISIALIGGSRVVILDEPSTGVDPCSRR---SIWDVISKNKTARtIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFylk 1568
Cdd:PRK13645   161 LAGIIAMDGNTLVLDEPTGGLDPKGEEdfiNLFERLNKEYKKR-IIMVTHNMDQVLRIADEVIVMHEGKVISIGSPF--- 236
                          250
                   ....*....|....*....
gi 2462571778 1569 EAFGDGYHLTLTKKKSPNL 1587
Cdd:PRK13645   237 EIFSNQELLTKIEIDPPKL 255
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
2278-2450 5.32e-19

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 87.41  E-value: 5.32e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVgYCPQEDALDDLVTVEEHLYF 2357
Cdd:TIGR01189   18 GLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEPHENIL-YLGHLPGLKPELSALENLHF 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2358 YARVHGipekDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISE 2437
Cdd:TIGR01189   97 WAAIHG----GAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVALLAGLLRA 172
                          170
                   ....*....|...
gi 2462571778 2438 EVQNKCSVILTSH 2450
Cdd:TIGR01189  173 HLARGGIVLLTTH 185
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
1371-1576 6.72e-19

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 93.57  E-value: 6.72e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1371 FYEGHITSLLGPNGAGKTTTISML-----TGLFGAsaGTIFVYGKDIktDLHTVRKNMGVCMQHDVLFSYLTTKEHLLLY 1445
Cdd:TIGR00955   48 AKPGELLAVMGSSGAGKTTLMNALafrspKGVKGS--GSVLLNGMPI--DAKEMRAISAYVQQDDLFIPTLTVREHLMFQ 123
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1446 GSIKVP-HWTKKQLHEEVKRTLKDTGLYSHRHKRVGT------LSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRR 1518
Cdd:TIGR00955  124 AHLRMPrRVTKKEKRERVDEVLQALGLRKCANTRIGVpgrvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAY 203
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1519 SIWDVISKNKTARTIILSTHHLDEAEV--LSDRIAFLEQGGLRCCGSPFYLKEAFGDGYH 1576
Cdd:TIGR00955  204 SVVQVLKGLAQKGKTIICTIHQPSSELfeLFDKIILMAEGRVAYLGSPDQAVPFFSDLGH 263
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
2275-2470 6.79e-19

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 92.77  E-value: 6.79e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHV-DSHSSLVGYCPQEDAL-DDLvTVE 2352
Cdd:COG1129     19 ALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPrDAQAAGIAIIHQELNLvPNL-SVA 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2353 EHLYF--YARVHG-IPEKDIKETVHKLLRRLHLM--PfkDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKS 2427
Cdd:COG1129     98 ENIFLgrEPRRGGlIDWRAMRRRARELLARLGLDidP--DTPVGDLSVAQQQLVEIARALSRDARVLILDEPTASLTERE 175
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 2462571778 2428 KRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKF 2470
Cdd:COG1129    176 VERLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRL 218
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
2238-2479 8.05e-19

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 92.94  E-value: 8.05e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2238 EDVRAERlRVESGAaefDLVQLYCLTKTYQLIHKKII-AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGN 2316
Cdd:TIGR03269  265 SEVEKEC-EVEVGE---PIIKVRNVSKRYISVDRGVVkAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGE 340
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2317 ILIR--------NKTGSLGHvDSHSSLVGYCPQEDALDDLVTVEEHL-----------------YFYARVHGIPEKDIKE 2371
Cdd:TIGR03269  341 VNVRvgdewvdmTKPGPDGR-GRAKRYIGILHQEYDLYPHRTVLDNLteaiglelpdelarmkaVITLKMVGFDEEKAEE 419
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2372 TVHKLlrrlhlmpfkdraTSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKII--SEEVQNKCSVILtS 2449
Cdd:TIGR03269  420 ILDKY-------------PDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSIlkAREEMEQTFIIV-S 485
                          250       260       270
                   ....*....|....*....|....*....|
gi 2462571778 2450 HSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:TIGR03269  486 HDMDFVLDVCDRAALMRDGKIVKIGDPEEI 515
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
2275-2510 8.60e-19

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 88.92  E-value: 8.60e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQE-DalDDLV--TV 2351
Cdd:PRK13635    22 ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDVRRQVGMVFQNpD--NQFVgaTV 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 EEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHL 2431
Cdd:PRK13635   100 QDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREV 179
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2432 WKIISEEVQNK-CSVILTSHSMEECeALCTRLAIMVNGKFQCIGSLQHIksrFGRG-----------FTVK--------- 2490
Cdd:PRK13635   180 LETVRQLKEQKgITVLSITHDLDEA-AQADRVIVMNKGEILEEGTPEEI---FKSGhmlqeigldvpFSVKlkellkrng 255
                          250       260
                   ....*....|....*....|.
gi 2462571778 2491 VHLKNNKVTMETLTKFM-QLH 2510
Cdd:PRK13635   256 ILLPNTYLTMESLVDELwTLH 276
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
1358-1582 9.35e-19

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 88.43  E-value: 9.35e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLF-----GASAGTIFVYGKDI-KTDLHTVRKNMGVCMQHDV 1431
Cdd:PRK14247    13 FGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIelypeARVSGEVYLDGQDIfKMDVIELRRRVQMVFQIPN 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1432 LFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRV----GTLSGGMKRKLSISIALIGGSRVVILDE 1507
Cdd:PRK14247    93 PIPNLSIFENVALGLKLNRLVKSKKELQERVRWALEKAQLWDEVKDRLdapaGKLSGGQQQRLCIARALAFQPEVLLADE 172
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1508 PSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSpfyLKEAFGDGYHlTLTKK 1582
Cdd:PRK14247   173 PTANLDPENTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGP---TREVFTNPRH-ELTEK 243
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
1358-1564 1.07e-18

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 88.50  E-value: 1.07e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSYL 1436
Cdd:PRK10253    17 YGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHyASKEVARRIGLLAQNATTPGDI 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1437 TTKEhllLYGSIKVPH------WtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:PRK10253    97 TVQE---LVARGRYPHqplftrW-RKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTT 172
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 1511 GVDPCSRRSIWDVISK-NKT-ARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK10253   173 WLDISHQIDLLELLSElNREkGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAP 228
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
1340-1540 1.62e-18

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 92.04  E-value: 1.62e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1340 PEPKDLTVGVA---LHGVTKIY-GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTD 1415
Cdd:TIGR02868  323 PAAGAVGLGKPtleLRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSL 402
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1416 LHT-VRKNMGVCMQHDVLFSyLTTKEHLLLyGSIKVPHwtkkqlhEEVKRTLKDTGLYSH-------RHKRVG----TLS 1483
Cdd:TIGR02868  403 DQDeVRRRVSVCAQDAHLFD-TTVRENLRL-ARPDATD-------EELWAALERVGLADWlralpdgLDTVLGeggaRLS 473
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1484 GGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHL 1540
Cdd:TIGR02868  474 GGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLAALSGRTVVLITHHL 530
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
1359-1564 1.99e-18

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 86.39  E-value: 1.99e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1359 GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSylt 1437
Cdd:cd03244     15 NLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKiGLHDLRSRISIIPQDPVLFS--- 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1438 tkehlllyGSIKV---PHwtkkQLH--EEVKRTLKDTGLYSH----------RHKRVGT-LSGGMKRKLSISIALIGGSR 1501
Cdd:cd03244     92 --------GTIRSnldPF----GEYsdEELWQALERVGLKEFveslpggldtVVEEGGEnLSVGQRQLLCLARALLRKSK 159
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1502 VVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDeaEVL-SDRIAFLEQGGLRCCGSP 1564
Cdd:cd03244    160 ILVLDEATASVDPETDALIQKTIREAFKDCTVLTIAHRLD--TIIdSDRILVLDKGRVVEFDSP 221
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
2275-2469 2.05e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 87.87  E-value: 2.05e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDalDDLV---TV 2351
Cdd:PRK13647    20 ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSKVGLVFQDP--DDQVfssTV 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 EEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHL 2431
Cdd:PRK13647    98 WDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETL 177
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 2462571778 2432 WKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK13647   178 MEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGR 215
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
1351-1556 2.11e-18

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 89.09  E-value: 2.11e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSK----VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI----KTDLHTVRKN 1422
Cdd:PRK11153     4 LKNISKVFPQGgrtiHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLtalsEKELRKARRQ 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1423 MGVCMQHdvlFSYLTTKEhllLYGSIKVP----HWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIG 1498
Cdd:PRK11153    84 IGMIFQH---FNLLSSRT---VFDNVALPlelaGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALAS 157
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1499 GSRVVILDEPSTGVDPCSRRSIWDVISK-NKTAR-TIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK11153   158 NPKVLLCDEATSALDPATTRSILELLKDiNRELGlTIVLITHEMDVVKRICDRVAVIDAG 217
ABC2_membrane_3 pfam12698
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ...
1916-2177 2.23e-18

ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.


Pssm-ID: 463674 [Multi-domain]  Cd Length: 345  Bit Score: 89.37  E-value: 2.23e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1916 FDITGVPANRTLAKVWYDPEGYHSLPAYLNSLNNFLLRVNMSKyDAARHGIIMYSHPYPGVQDQEQATISSLIDILVALS 1995
Cdd:pfam12698   89 FSKDLLKGESATVTVYINSSNLLVSKLILNALQSLLQQLNASA-LVLLLEALSTSAPIPVESTPLFNPQSGYAYYLVGLI 167
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1996 ILMGYSVTTASFVTYVVREHQTKAKQLQHISGIGVTCYWVTNFIYDMVFYLVPVAFSIGIIAIFKLPAfyseNNLGAVSL 2075
Cdd:pfam12698  168 LMIIILIGAAIIAVSIVEEKESRIKERLLVSGVSPLQYWLGKILGDFLVGLLQLLIILLLLFGIGIPF----GNLGLLLL 243
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2076 LLLLFGYATFSWMYLLAGLFHETGMAFITYVCVNLFFGINSIVSLsvvyflskekpndpTLELISETLKRIFLIFPQFCF 2155
Cdd:pfam12698  244 LFLLYGLAYIALGYLLGSLFKNSEDAQSIIGIVILLLSGFFGGLF--------------PLEDPPSFLQWIFSIIPFFSP 309
                          250       260
                   ....*....|....*....|..
gi 2462571778 2156 GYGLIELSQQQSVLDFLKAYGV 2177
Cdd:pfam12698  310 IDGLLRLIYGDSLWEIAPSLII 331
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
1348-1558 3.07e-18

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 86.61  E-value: 3.07e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1348 GVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGK--DIKTDLHT-----VR 1420
Cdd:COG4161      2 SIQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHqfDFSQKPSEkairlLR 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1421 KNMGVCMQHDVLFSYLTTKEHLLlYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGS 1500
Cdd:COG4161     82 QKVGMVFQQYNLWPHLTVMENLI-EAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEP 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1501 RVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGL 1558
Cdd:COG4161    161 QVLLFDEPTAALDPEITAQVVEIIRElSQTGITQVIVTHEVEFARKVASQVVYMEKGRI 219
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
2272-2469 3.51e-18

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 85.72  E-value: 3.51e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2272 KIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALddlvtv 2351
Cdd:cd03245     16 EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRNIGYVPQDVTL------ 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 eehlyFYARVH-----GIPEKDIKE--------TVHKLLRRLHL---MPFKDRATSMcSYGTKRKLSTALALIGKPSILL 2415
Cdd:cd03245     90 -----FYGTLRdnitlGAPLADDERilraaelaGVTDFVNKHPNgldLQIGERGRGL-SGGQRQAVALARALLNDPPILL 163
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 2416 LDEPSSGMDPKSKRHLWKIISEEVQNKcSVILTSH--SMEEceaLCTRLAIMVNGK 2469
Cdd:cd03245    164 LDEPTSAMDMNSEERLKERLRQLLGDK-TLIIITHrpSLLD---LVDRIIVMDSGR 215
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1359-1559 3.95e-18

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 86.84  E-value: 3.95e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1359 GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT---DlhtvRknmGVCMQHDVLFSY 1435
Cdd:COG4525     18 QPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGpgaD----R---GVVFQKDALLPW 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 LTTKEH----LLLYGsikVPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTG 1511
Cdd:COG4525     91 LNVLDNvafgLRLRG---VP---KAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGA 164
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1512 VDPCSRRS-------IWdviskNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLR 1559
Cdd:COG4525    165 LDALTREQmqellldVW-----QRTGKGVFLITHSVEEALFLATRLVVMSPGPGR 214
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
1354-1556 5.21e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 87.45  E-value: 5.21e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1354 VTKIYGSKV-----AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTI-FVYgKDIKTDLHT--------- 1418
Cdd:PRK13651     8 IVKIFNKKLptelkALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIeWIF-KDEKNKKKTkekekvlek 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1419 ----------------VRKNMGVCMQHDVLFSYLTTKEHLLLYG--SIKVPhwtKKQLHEEVKRTLKDTGL-YSHRHKRV 1479
Cdd:PRK13651    87 lviqktrfkkikkikeIRRRVGVVFQFAEYQLFEQTIEKDIIFGpvSMGVS---KEEAKKRAAKYIELVGLdESYLQRSP 163
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1480 GTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK13651   164 FELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNlNKQGKTIILVTHDLDNVLEWTKRTIFFKDG 241
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
1365-1564 5.23e-18

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 85.74  E-value: 5.23e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1365 DNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSylTTKEHLL 1443
Cdd:cd03253     18 KDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREvTLDSLRRAIGVVPQDTVLFN--DTIGYNI 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1444 LYGSIKVphwTKKQ---------LHEEVKRTLK--DT-----GLYshrhkrvgtLSGGMKRKLSISIALIGGSRVVILDE 1507
Cdd:cd03253     96 RYGRPDA---TDEEvieaakaaqIHDKIMRFPDgyDTivgerGLK---------LSGGEKQRVAIARAILKNPPILLLDE 163
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1508 PSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAeVLSDRIAFLEQGGLRCCGSP 1564
Cdd:cd03253    164 ATSALDTHTEREIQAALRDVSKGRTTIVIAHRLSTI-VNADKIIVLKDGRIVERGTH 219
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
1349-1557 5.46e-18

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 85.75  E-value: 5.46e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKV--AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGV 1425
Cdd:cd03251      1 VEFKNVTFRYPGDGppVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDyTLASLRRQIGL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1426 CMQHDVLFSylTTKEHLLLYGSIKVPhwtkkqlHEEVKRTLK-----------DTGLYSHRHKRVGTLSGGMKRKLSISI 1494
Cdd:cd03251     81 VSQDVFLFN--DTVAENIAYGRPGAT-------REEVEEAARaanahefimelPEGYDTVIGERGVKLSGGQRQRIAIAR 151
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1495 ALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVlSDRIAFLEQGG 1557
Cdd:cd03251    152 ALLKDPPILILDEATSALDTESERLVQAALERLMKNRTTFVIAHRLSTIEN-ADRIVVLEDGK 213
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
1333-1564 6.63e-18

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 88.55  E-value: 6.63e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1333 MFSSNIEPEPKDLTVGVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI 1412
Cdd:PRK10070    13 IFGEHPQRAFKYIEQGLSKEQILEKTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDI 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1413 ----KTDLHTVR-KNMGVCMQHDVLFSYLTTKEHLLLygSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMK 1487
Cdd:PRK10070    93 akisDAELREVRrKKIAMVFQSFALMPHMTVLDNTAF--GMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMR 170
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1488 RKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK10070   171 QRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKlqAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTP 249
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
1317-1577 9.92e-18

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 90.17  E-value: 9.92e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1317 MMQNTnpSASKTSPEYM-----FSSNIEPEPKDLTVGVALHGVTKIYGSKVAV---DNLNLNFYEGHITSLLGPNGAGKT 1388
Cdd:TIGR00958  444 MMQAV--GASEKVFEYLdrkpnIPLTGTLAPLNLEGLIEFQDVSFSYPNRPDVpvlKGLTFTLHPGEVVALVGPSGSGKS 521
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1389 TTISMLTGLFGASAGTIFVYGKDI-KTDLHTVRKNMGVCMQHDVLFSylTTKEHLLLYGSIKVPhwtKKQLHEEVKRTLK 1467
Cdd:TIGR00958  522 TVAALLQNLYQPTGGQVLLDGVPLvQYDHHYLHRQVALVGQEPVLFS--GSVRENIAYGLTDTP---DEEIMAAAKAANA 596
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1468 D---TGLYSHRHKRVGT----LSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDviSKNKTARTIILSTHHL 1540
Cdd:TIGR00958  597 HdfiMEFPNGYDTEVGEkgsqLSGGQKQRIAIARALVRKPRVLILDEATSALDAECEQLLQE--SRSRASRTVLLIAHRL 674
                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 2462571778 1541 DEAEVlSDRIAFLEQGGLRCCGSPFYLKEAFGDGYHL 1577
Cdd:TIGR00958  675 STVER-ADQILVLKKGSVVEMGTHKQLMEDQGCYKHL 710
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
2262-2469 1.08e-17

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 87.06  E-value: 1.08e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK-TGSLghvdSHSSL----- 2335
Cdd:COG1135      7 LSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVdLTAL----SERELraarr 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2336 -VGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLmpfKDRATsmcSY------GTKRKLSTALALI 2408
Cdd:COG1135     83 kIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGL---SDKAD---AYpsqlsgGQKQRVGIARALA 156
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 2409 GKPSILLLDEPSSGMDPKSKR---HLWKIISEEVqnKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:COG1135    157 NNPKVLLCDEATSALDPETTRsilDLLKDINREL--GLTIVLITHEMDVVRRICDRVAVLENGR 218
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
2275-2469 1.19e-17

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 84.68  E-value: 1.19e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSL------VGYCPQEDALDDL 2348
Cdd:PRK11124    17 ALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFSKTPSDKAIrelrrnVGMVFQQYNLWPH 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2349 VTVEEHLyFYA--RVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPK 2426
Cdd:PRK11124    97 LTVQQNL-IEApcRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPE 175
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 2462571778 2427 SKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK11124   176 ITAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGH 218
cbiO PRK13646
energy-coupling factor transporter ATPase;
1361-1581 1.22e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 85.99  E-value: 1.22e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1361 KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI--KTD---LHTVRKNMGVCMQHDVLFSY 1435
Cdd:PRK13646    20 HQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITIthKTKdkyIRPVRKRIGMVFQFPESQLF 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 LTTKEHLLLYGsikvPHWTKKQLhEEVK----RTLKDTGLYSH-RHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:PRK13646   100 EDTVEREIIFG----PKNFKMNL-DEVKnyahRLLMDLGFSRDvMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTA 174
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1511 GVDPCSRRSIWDVISKNKTA--RTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPfylKEAFGDG-----YHLTLTK 1581
Cdd:PRK13646   175 GLDPQSKRQVMRLLKSLQTDenKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSP---KELFKDKkkladWHIGLPE 249
cbiO PRK13643
energy-coupling factor transporter ATPase;
1363-1564 1.25e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 85.94  E-value: 1.25e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGT-----IFVYGKDIKTDLHTVRKNMGVCMQ--HDVLFSY 1435
Cdd:PRK13643    21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKvtvgdIVVSSTSKQKEIKPVRKKVGVVFQfpESQLFEE 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 LTTKEHLLLYGSIKVphwTKKQLHEEVKRTLKDTGLYSH-RHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDP 1514
Cdd:PRK13643   101 TVLKDVAFGPQNFGI---PKEKAEKIAAEKLEMVGLADEfWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDP 177
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1515 CSRRSIWDVI-SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK13643   178 KARIEMMQLFeSIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTP 228
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
1358-1559 1.85e-17

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 84.83  E-value: 1.85e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTI---SMLTGLF-GASA-GTIFVYGKDI---KTDLHTVRKNMGVCMQH 1429
Cdd:PRK14243    20 YGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILrcfNRLNDLIpGFRVeGKVTFHGKNLyapDVDPVEVRRRIGMVFQK 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYlTTKEHlLLYGSiKVPHWtKKQLHEEVKRTLKDTGLYSH---RHKRVG-TLSGGMKRKLSISIALIGGSRVVIL 1505
Cdd:PRK14243   100 PNPFPK-SIYDN-IAYGA-RINGY-KGDMDELVERSLRQAALWDEvkdKLKQSGlSLSGGQQQRLCIARAIAVQPEVILM 175
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1506 DEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAF----LEQGGLR 1559
Cdd:PRK14243   176 DEPCSALDPISTLRIEELMHELKEQYTIIIVTHNMQQAARVSDMTAFfnveLTEGGGR 233
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
2279-2450 2.29e-17

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 82.93  E-value: 2.29e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2279 ISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrNKTGSLGHVDSHSSLVGYCPQEDALDDLVTVEEHLYFY 2358
Cdd:cd03231     19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLL-NGGPLDFQRDSIARGLLYLGHAPGIKTTLSVLENLRFW 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2359 ARVHGipekdiKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEE 2438
Cdd:cd03231     98 HADHS------DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAGH 171
                          170
                   ....*....|..
gi 2462571778 2439 VQNKCSVILTSH 2450
Cdd:cd03231    172 CARGGMVVLTTH 183
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
1349-1550 2.45e-17

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 88.11  E-value: 2.45e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIY-GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVC 1426
Cdd:TIGR02857  322 LEFSGVSVAYpGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADaDADSWRDQIAWV 401
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 MQHDVLFsYLTTKEHLLLYgsikvphwTKKQLHEEVKRTLKDTGLYS-------HRHKRVGT----LSGGMKRKLSISIA 1495
Cdd:TIGR02857  402 PQHPFLF-AGTIAENIRLA--------RPDASDAEIREALERAGLDEfvaalpqGLDTPIGEggagLSGGQAQRLALARA 472
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1496 LIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEvLSDRI 1550
Cdd:TIGR02857  473 FLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQGRTVLLVTHRLALAA-LADRI 526
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
1358-1562 2.49e-17

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 83.35  E-value: 2.49e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKdIKTDLhtvrkNMGVCMQHDvlfsyLT 1437
Cdd:cd03220     32 VGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGR-VSSLL-----GLGGGFNPE-----LT 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1438 TKEHLLLYGSIKvpHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSR 1517
Cdd:cd03220    101 GRENIYLNGRLL--GLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQ 178
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462571778 1518 RSIWDVI-SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCG 1562
Cdd:cd03220    179 EKCQRRLrELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
2275-2470 2.82e-17

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 82.09  E-value: 2.82e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSL-VGYCPqEDALDDLVtvee 2353
Cdd:cd03215     15 AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAIRAgIAYVP-EDRKREGL---- 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 hlyfyarvhgIPEKDIKETVhkLLRRLhLmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWK 2433
Cdd:cd03215     90 ----------VLDLSVAENI--ALSSL-L-----------SGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYR 145
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2462571778 2434 IISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKF 2470
Cdd:cd03215    146 LIRELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
1367-1564 3.17e-17

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 85.93  E-value: 3.17e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1367 LNLNF-YEGH-ITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-----KTDLHTVRKNMGVCMQHDVLFSYLTTK 1439
Cdd:TIGR02142   14 LDADFtLPGQgVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLfdsrkGIFLPPEKRRIGYVFQEARLFPHLSVR 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1440 EHLLlYGSIKVPHWTKKQLHEEVKRTLkdtGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRS 1519
Cdd:TIGR02142   94 GNLR-YGMKRARPSERRISFERVIELL---GIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYE 169
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 1520 IWDVIsKNKTART---IILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:TIGR02142  170 ILPYL-ERLHAEFgipILYVSHSLQEVLRLADRVVVLEDGRVAAAGPI 216
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
2247-2479 4.06e-17

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 83.56  E-value: 4.06e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2247 VESGAAEFDLvqlYCLTKTYQLIHKKIIaVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSL 2326
Cdd:PRK14246     1 MEAGKSAEDV---FNISRLYLYINDKAI-LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYF 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2327 G----HVDSHS--SLVGYCPQEDALDDLVTVEEHLYFYARVHGIPEK-DIKETVHKLLRRLHLMP-FKDR---ATSMCSY 2395
Cdd:PRK14246    77 GkdifQIDAIKlrKEVGMVFQQPNPFPHLSIYDNIAYPLKSHGIKEKrEIKKIVEECLRKVGLWKeVYDRlnsPASQLSG 156
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2396 GTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISeEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGS 2475
Cdd:PRK14246   157 GQQQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLIT-ELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGS 235

                   ....
gi 2462571778 2476 LQHI 2479
Cdd:PRK14246   236 SNEI 239
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
2212-2469 4.33e-17

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 87.43  E-value: 4.33e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2212 ESLIKKLRLFFRKFNSSHVRET-----IDEDEDVRAERLRVESGAAEF----------DLVQLYCLTKTYQliHKKIIav 2276
Cdd:COG0488    256 QKKIAKEEEFIRRFRAKARKAKqaqsrIKALEKLEREEPPRRDKTVEIrfppperlgkKVLELEGLSKSYG--DKTLL-- 331
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2277 NNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIlirnKTGSlgHVDshsslVGYCPQE-DALDDLVTVEEHL 2355
Cdd:COG0488    332 DDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTV----KLGE--TVK-----IGYFDQHqEELDPDKTVLDEL 400
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2356 YFYArvhgipEKDIKETVHKLLRRlhlMPFK-DRA---TSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHL 2431
Cdd:COG0488    401 RDGA------PGGTEQEVRGYLGR---FLFSgDDAfkpVGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIETLEAL 471
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2462571778 2432 wkiisEEV-QN-KCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:COG0488    472 -----EEAlDDfPGTVLLVSHDRYFLDRVATRILEFEDGG 506
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
1351-1556 4.66e-17

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 83.14  E-value: 4.66e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTI------FVYGKDIKT-DLHTVRKNM 1423
Cdd:PRK11124     5 LNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLniagnhFDFSKTPSDkAIRELRRNV 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1424 GVCMQHDVLFSYLTTKEHlLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVV 1503
Cdd:PRK11124    85 GMVFQQYNLWPHLTVQQN-LIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVL 163
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1504 ILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK11124   164 LFDEPTAALDPEITAQIVSIIRElAETGITQVIVTHEVEVARKTASRVVYMENG 217
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
2276-2469 4.89e-17

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 81.11  E-value: 4.89e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALddlvtveehl 2355
Cdd:cd03246     18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDHVGYLPQDDEL---------- 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2356 yfyarvhgipekdiketvhkllrrlhlmpFKDR-ATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKI 2434
Cdd:cd03246     88 -----------------------------FSGSiAENILSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQA 138
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2462571778 2435 ISEEVQNKCSVILTSHSMEECEAlCTRLAIMVNGK 2469
Cdd:cd03246    139 IAALKAAGATRIVIAHRPETLAS-ADRILVLEDGR 172
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
1349-1563 6.56e-17

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 82.53  E-value: 6.56e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYG--SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGV 1425
Cdd:cd03252      1 ITFEHVRFRYKpdGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALaDPAWLRRQVGV 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1426 CMQHDVLFS-------YLT----TKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGlyshrhkrVGtLSGGMKRKLSISI 1494
Cdd:cd03252     81 VLQENVLFNrsirdniALAdpgmSMERVIEAAKLAGAHDFISELPEGYDTIVGEQG--------AG-LSGGQRQRIAIAR 151
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1495 ALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVlSDRIAFLEQGGLRCCGS 1563
Cdd:cd03252    152 ALIHNPRILIFDEATSALDYESEHAIMRNMHDICAGRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGS 219
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
1358-1556 6.72e-17

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 82.83  E-value: 6.72e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDlhtvRKNMGVCMQHDVLFSYLT 1437
Cdd:PRK11248    11 YGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGP----GAERGVVFQNEGLLPWRN 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1438 TKEH----LLLYGsikVPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVD 1513
Cdd:PRK11248    87 VQDNvafgLQLAG---VE---KMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD 160
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2462571778 1514 PCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK11248   161 AFTREQMQTLLLKlwQETGKQVLLITHDIEEAVFMATELVLLSPG 205
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
1342-1558 8.01e-17

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 82.13  E-value: 8.01e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1342 PKDLTVGVALHGVTKIYGSKVAV---DNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHT 1418
Cdd:cd03248      5 PDHLKGIVKFQNVTFAYPTRPDTlvlQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHK 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1419 -VRKNMGVCMQHDVLFSYLTTKEhlLLYGSIKVPHWTKKQL----HEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSIS 1493
Cdd:cd03248     85 yLHSKVSLVGQEPVLFARSLQDN--IAYGLQSCSFECVKEAaqkaHAHSFISELASGYDTEVGEKGSQLSGGQKQRVAIA 162
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1494 IALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEvLSDRIAFLEQGGL 1558
Cdd:cd03248    163 RALIRNPQVLILDEATSALDAESEQQVQQALYDWPERRTVLVIAHRLSTVE-RADQILVLDGGRI 226
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
2255-2483 8.50e-17

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 84.77  E-value: 8.50e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2255 DLVQLYCLTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRnktgslGHVDSHSS 2334
Cdd:PRK11432     5 NFVVLKNITKRF----GSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFID------GEDVTHRS 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2335 LvgycPQED--------ALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALA 2406
Cdd:PRK11432    75 I----QQRDicmvfqsyALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARA 150
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2407 LIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQ--NKCSVILTsHSMEECEALCTRLAIMVNGKFQCIGSLQ----HIK 2480
Cdd:PRK11432   151 LILKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVT-HDQSEAFAVSDTVIVMNKGKIMQIGSPQelyrQPA 229

                   ...
gi 2462571778 2481 SRF 2483
Cdd:PRK11432   230 SRF 232
cbiO PRK13644
energy-coupling factor transporter ATPase;
2275-2481 9.60e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 83.11  E-value: 9.60e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRN-KTGSLGHVDSHSSLVGYCPQEDALDDL-VTVE 2352
Cdd:PRK13644    17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGiDTGDFSKLQGIRKLVGIVFQNPETQFVgRTVE 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2353 EHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLW 2432
Cdd:PRK13644    97 EDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVL 176
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 2433 KIISEEVQNKCSVILTSHSMEECEAlCTRLAIMVNGKFQCIGSLQHIKS 2481
Cdd:PRK13644   177 ERIKKLHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGEPENVLS 224
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
1349-1562 1.35e-16

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 85.61  E-value: 1.35e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCM- 1427
Cdd:PRK09700     6 ISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLGIGIi 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 -QHDVLFSYLTTKEHLLL-------YGSIKVPHWTKKQLHEEVkrTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGG 1499
Cdd:PRK09700    86 yQELSVIDELTVLENLYIgrhltkkVCGVNIIDWREMRVRAAM--MLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLD 163
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1500 SRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCG 1562
Cdd:PRK09700   164 AKVIIMDEPTSSLTNKEVDYLFLIMNQlRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSG 227
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
1349-1585 1.35e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 83.36  E-value: 1.35e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSK-----VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTI----FVYGKDIKTDLHT- 1418
Cdd:PRK13631    22 LRVKNLYCVFDEKqenelVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIqvgdIYIGDKKNNHELIt 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1419 ------------VRKNMGVCMQHDVLFSYLTTKEHLLLYGSI--KVPhwtKKQLHEEVKRTLKDTGL-YSHRHKRVGTLS 1483
Cdd:PRK13631   102 npyskkiknfkeLRRRVSMVFQFPEYQLFKDTIEKDIMFGPValGVK---KSEAKKLAKFYLNKMGLdDSYLERSPFGLS 178
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1484 GGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNK-TARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCG 1562
Cdd:PRK13631   179 GGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKaNNKTVFVITHTMEHVLEVADEVIVMDKGKILKTG 258
                          250       260
                   ....*....|....*....|...
gi 2462571778 1563 SPFylkEAFGDGYHLTLTKKKSP 1585
Cdd:PRK13631   259 TPY---EIFTDQHIINSTSIQVP 278
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
1340-1556 1.64e-16

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 85.78  E-value: 1.64e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1340 PEPKDLTVGVALHGVTKIY-GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLH 1417
Cdd:PRK13657   326 IDLGRVKGAVEFDDVSFSYdNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTvTRA 405
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1418 TVRKNMGVCMQHDVLFSYlTTKEHLllygSIKVPHWTKKQLHEEVKRT-------LKDTGLYSHRHKRVGTLSGGMKRKL 1490
Cdd:PRK13657   406 SLRRNIAVVFQDAGLFNR-SIEDNI----RVGRPDATDEEMRAAAERAqahdfieRKPDGYDTVVGERGRQLSGGERQRL 480
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1491 SISIALIGGSRVVILDEPSTGVDPCSRRSI---WDVISKNKTARTII--LSThhLDEAevlsDRIAFLEQG 1556
Cdd:PRK13657   481 AIARALLKDPPILILDEATSALDVETEAKVkaaLDELMKGRTTFIIAhrLST--VRNA----DRILVFDNG 545
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
1356-1587 1.65e-16

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 81.94  E-value: 1.65e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1356 KIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI--------------KTDLHTVRK 1421
Cdd:PRK10619    13 KRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTInlvrdkdgqlkvadKNQLRLLRT 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1422 NMGVCMQHDVLFSYLTTKEHlLLYGSIKVPHWTKKQLHEEVKRTLKDTGL-YSHRHKRVGTLSGGMKRKLSISIALIGGS 1500
Cdd:PRK10619    93 RLTMVFQHFNLWSHMTVLEN-VMEAPIQVLGLSKQEARERAVKYLAKVGIdERAQGKYPVHLSGGQQQRVSIARALAMEP 171
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1501 RVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPfylKEAFGDgyhltl 1579
Cdd:PRK10619   172 EVLLFDEPTSALDPELVGEVLRIMQQlAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAP---EQLFGN------ 242

                   ....*...
gi 2462571778 1580 tkKKSPNL 1587
Cdd:PRK10619   243 --PQSPRL 248
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
1350-1556 1.67e-16

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 85.44  E-value: 1.67e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1350 ALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI--KTDLHTVRKNMGVCM 1427
Cdd:PRK10762     6 QLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVtfNGPKSSQEAGIGIIH 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QHDVLFSYLTTKEHLLL-------YGSIKvphWtkKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGS 1500
Cdd:PRK10762    86 QELNLIPQLTIAENIFLgrefvnrFGRID---W--KKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFES 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1501 RVVILDEPSTGVDPCSRRSIWDVISKNKTA-RTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK10762   161 KVIIMDEPTDALTDTETESLFRVIRELKSQgRGIVYISHRLKEIFEICDDVTVFRDG 217
cbiO PRK13646
energy-coupling factor transporter ATPase;
2275-2472 1.78e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 82.52  E-value: 1.78e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGN-----ILIRNKTGS--LGHVDSHSSLVGYCPQEDALDD 2347
Cdd:PRK13646    22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTvtvddITITHKTKDkyIRPVRKRIGMVFQFPESQLFED 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2348 lvTVEEHLYFYARVHGIPEKDIKETVHKLLRRL-------HLMPFKdratsmCSYGTKRKLSTALALIGKPSILLLDEPS 2420
Cdd:PRK13646   102 --TVEREIIFGPKNFKMNLDEVKNYAHRLLMDLgfsrdvmSQSPFQ------MSGGQMRKIAIVSILAMNPDIIVLDEPT 173
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 2421 SGMDPKSKRHLWKIISE--EVQNKcSVILTSHSMEECEALCTRLAIMVNGK--FQC 2472
Cdd:PRK13646   174 AGLDPQSKRQVMRLLKSlqTDENK-TIILVSHDMNEVARYADEVIVMKEGSivSQT 228
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
1342-1564 2.07e-16

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 83.73  E-value: 2.07e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1342 PKDLTVGVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRK 1421
Cdd:PRK11607    13 RKALTPLLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDL-SHVPPYQR 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1422 NMGVCMQHDVLFSYLTTKEHLLLygSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSR 1501
Cdd:PRK11607    92 PINMMFQSYALFPHMTVEQNIAF--GLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPK 169
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1502 VVILDEPSTGVDPCSRR----SIWDVISknKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK11607   170 LLLLDEPMGALDKKLRDrmqlEVVDILE--RVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEP 234
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
1358-1543 2.47e-16

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 79.59  E-value: 2.47e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI------KTDLH-----TVRK--NMG 1424
Cdd:NF040873     2 YGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARvayvpqRSEVPdslplTVRDlvAMG 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1425 VcMQHDVLFSYLTTKEHLllygsikvphwtkkqlheEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:NF040873    82 R-WARRGLWRRLTRDDRA------------------AVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLL 142
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEA 1543
Cdd:NF040873   143 LDEPTTGLDAESRERIIALLAEeHARGATVVVVTHDLELV 182
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
1349-1547 2.60e-16

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 81.74  E-value: 2.60e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI----KTDLHTVRKNMG 1424
Cdd:PRK11831     8 VDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIpamsRSRLYTVRKRMS 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1425 VCMQHDVLFSYLTtkehllLYGSIKVPHWTKKQLHEEVKRT-----LKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGG 1499
Cdd:PRK11831    88 MLFQSGALFTDMN------VFDNVAYPLREHTQLPAPLLHStvmmkLEAVGLRGAAKLMPSELSGGMARRAALARAIALE 161
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1500 SRVVILDEPSTGVDPCSRRSIWDVISKNKTAR--TIILSTHhlDEAEVLS 1547
Cdd:PRK11831   162 PDLIMFDEPFVGQDPITMGVLVKLISELNSALgvTCVVVSH--DVPEVLS 209
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
2261-2469 2.63e-16

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 80.69  E-value: 2.63e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2261 CLTKTYQLIHKkiiAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIR-NKTGSLGHVD--SHSSLVG 2337
Cdd:cd03256      5 NLSKTYPNGKK---ALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDgTDINKLKGKAlrQLRRQIG 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2338 YCPQEDALDDLVTVEE---------HLYFYARVHGIPEKDIKETVHkLLRRLHLmpfKDRATSMCSY---GTKRKLSTAL 2405
Cdd:cd03256     82 MIFQQFNLIERLSVLEnvlsgrlgrRSTWRSLFGLFPKEEKQRALA-ALERVGL---LDKAYQRADQlsgGQQQRVAIAR 157
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 2406 ALIGKPSILLLDEPSSGMDPKSKR---HLWKIISEEVQnkCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03256    158 ALMQQPKLILADEPVASLDPASSRqvmDLLKRINREEG--ITVIVSLHQVDLAREYADRIVGLKDGR 222
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
2278-2451 2.86e-16

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 79.92  E-value: 2.86e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRnktGSLGHVDSHSSLVGYCPQEDALDDLVTVEEHLYF 2357
Cdd:PRK13539    20 GLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLD---GGDIDDPDVAEACHYLGHRNAMKPALTVAENLEF 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2358 YARVHGIPEKDIKETvhklLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISE 2437
Cdd:PRK13539    97 WAAFLGGEELDIAAA----LEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRA 172
                          170
                   ....*....|....
gi 2462571778 2438 EVQNKCSVILTSHS 2451
Cdd:PRK13539   173 HLAQGGIVIAATHI 186
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
1363-1551 4.39e-16

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 82.02  E-value: 4.39e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGL---FGASAGTIFVYGKDI----KTDLHTVR-KNMGVCMQhDVLFS 1434
Cdd:COG0444     20 AVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLlppPGITSGEILFDGEDLlklsEKELRKIRgREIQMIFQ-DPMTS 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1435 ---YLTTKEH----LLLYGSIkvphwTKKQLHEEVKRTLKDTGL---------YSHRhkrvgtLSGGMKRKLSISIALIG 1498
Cdd:COG0444     99 lnpVMTVGDQiaepLRIHGGL-----SKAEARERAIELLERVGLpdperrldrYPHE------LSGGMRQRVMIARALAL 167
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1499 GSRVVILDEPSTGVDPCSRRSIWDVIS--KNKTARTIILSTHHLDEAEVLSDRIA 1551
Cdd:COG0444    168 EPKLLIADEPTTALDVTIQAQILNLLKdlQRELGLAILFITHDLGVVAEIADRVA 222
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
1358-1564 4.64e-16

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 82.97  E-value: 4.64e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIK-TDLHTVRKNMGVCMQhDVLFSYL 1436
Cdd:PRK09536    13 FGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEaLSARAASRRVASVPQ-DTSLSFE 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1437 TTKEHLLLYGsiKVPHWTKKQLHEE-----VKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTG 1511
Cdd:PRK09536    92 FDVRQVVEMG--RTPHRSRFDTWTEtdraaVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTAS 169
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1512 VDPCSR-RSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK09536   170 LDINHQvRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPP 223
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
1363-1564 4.70e-16

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 84.08  E-value: 4.70e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHT--------VRKNMGVCMQHDVLFS 1434
Cdd:TIGR03269  299 AVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRVGDEWVDMTKpgpdgrgrAKRYIGILHQEYDLYP 378
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1435 YLTTKEHLLLYGSIKVPhwtkkqlhEEVKR-----TLKDTGLYSHRHKRV-----GTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:TIGR03269  379 HRTVLDNLTEAIGLELP--------DELARmkaviTLKMVGFDEEKAEEIldkypDELSEGERHRVALAQVLIKEPRIVI 450
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVI--SKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:TIGR03269  451 LDEPTGTMDPITKVDVTHSIlkAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDP 512
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
2275-2454 4.87e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 80.95  E-value: 4.87e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK---TGSLGHVDSHSSLVGYCPQEDALDDlvTV 2351
Cdd:PRK13648    24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQaitDDNFEKLRKHIGIVFQNPDNQFVGS--IV 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 EEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHL 2431
Cdd:PRK13648   102 KYDVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNL 181
                          170       180
                   ....*....|....*....|....
gi 2462571778 2432 WKIISEEVQNK-CSVILTSHSMEE 2454
Cdd:PRK13648   182 LDLVRKVKSEHnITIISITHDLSE 205
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
2275-2453 4.93e-16

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 84.04  E-value: 4.93e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSHS--SLVGYCPQEDAL-DDlvTV 2351
Cdd:COG4988    352 ALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGV--DLSDLDPASwrRQIAWVPQNPYLfAG--TI 427
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 EEHLYFYArvhgiPEKDiKETVHKLLRRLHLMPF------------KDRATSMcSYGTKRKLSTALALIGKPSILLLDEP 2419
Cdd:COG4988    428 RENLRLGR-----PDAS-DEELEAALEAAGLDEFvaalpdgldtplGEGGRGL-SGGQAQRLALARALLRDAPLLLLDEP 500
                          170       180       190
                   ....*....|....*....|....*....|....
gi 2462571778 2420 SSGMDPKSKRHLWKIISEEVQNKCsVILTSHSME 2453
Cdd:COG4988    501 TAHLDAETEAEILQALRRLAKGRT-VILITHRLA 533
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
1348-1572 5.68e-16

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 82.09  E-value: 5.68e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1348 GVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTiSMLTGLFGASAGT----IFVYGKDIKTDLHTVRKNM 1423
Cdd:NF000106    13 AVEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRrpwrF*TWCANRRALRRTIG*HR 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1424 GVCMQHDVLFSyltTKEHLLLYGsiKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVV 1503
Cdd:NF000106    92 PVR*GRRESFS---GRENLYMIG--R*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVL 166
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1504 ILDEPSTGVDPCSRRSIWD-VISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFG 1572
Cdd:NF000106   167 YLDEPTTGLDPRTRNEVWDeVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG 236
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
1365-1557 5.99e-16

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 79.89  E-value: 5.99e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1365 DNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSyLTTKEHlL 1443
Cdd:cd03249     20 KGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDlNLRWLRSQIGLVSQEPVLFD-GTIAEN-I 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1444 LYGSIKVPhwtkkqlHEEVKRTLKDTGLYS------HR-HKRVG----TLSGGMKRKLSISIALIGGSRVVILDEPSTGV 1512
Cdd:cd03249     98 RYGKPDAT-------DEEVEEAAKKANIHDfimslpDGyDTLVGergsQLSGGQKQRIAIARALLRNPKILLLDEATSAL 170
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2462571778 1513 DPCSRRSIWDVISKNKTARTIILSTHHLDEAEVlSDRIAFLEQGG 1557
Cdd:cd03249    171 DAESEKLVQEALDRAMKGRTTIVIAHRLSTIRN-ADLIAVLQNGQ 214
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
2265-2470 7.43e-16

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 77.74  E-value: 7.43e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2265 TYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRnktgslghvDSHSSLVgycpqEDA 2344
Cdd:cd03247      7 SFSYPEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLD---------GVPVSDL-----EKA 72
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2345 LDDLVTV---EEHLYfyarvhgipEKDIKETVHkllRRLhlmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:cd03247     73 LSSLISVlnqRPYLF---------DTTLRNNLG---RRF-------------SGGERQRLALARILLQDAPIVLLDEPTV 127
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 2422 GMDPKSKRHLWKIISEEVQNKCSVILTSH--SMEECEALCtrlaIMVNGKF 2470
Cdd:cd03247    128 GLDPITERQLLSLIFEVLKDKTLIWITHHltGIEHMDKIL----FLENGKI 174
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
2280-2469 7.68e-16

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 78.69  E-value: 7.68e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2280 SIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSHSSLVGYCPQEDALDDLVTVEEH--LYF 2357
Cdd:cd03298     18 DLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGV--DVTAAPPADRPVSMLFQENNLFAHLTVEQNvgLGL 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2358 YARVHGIPEKdiKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISE 2437
Cdd:cd03298     96 SPGLKLTAED--RQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLD 173
                          170       180       190
                   ....*....|....*....|....*....|...
gi 2462571778 2438 -EVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03298    174 lHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGR 206
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
1348-1576 7.68e-16

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 82.00  E-value: 7.68e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1348 GVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGVCM 1427
Cdd:PRK11000     3 SVTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRM-NDVPPAERGVGMVF 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QHDVLFSYLTTKEH----LLLYGSIKVphwTKKQLHEEVKRTLKDTGLYSHRHKrvgTLSGGMKRKLSISIALIGGSRVV 1503
Cdd:PRK11000    82 QSYALYPHLSVAENmsfgLKLAGAKKE---EINQRVNQVAEVLQLAHLLDRKPK---ALSGGQRQRVAIGRTLVAEPSVF 155
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1504 ILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLkeafgdgYH 1576
Cdd:PRK11000   156 LLDEPLSNLDAALRVQMRIEISRlhKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLEL-------YH 223
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
2262-2469 7.82e-16

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 83.15  E-value: 7.82e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKT---GS--------LGHVD 2330
Cdd:COG3845     11 ITKRF----GGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPvriRSprdaialgIGMVH 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2331 SHSSLVgycpqeDALddlvTVEEHLYFYA---RVHGIPEKDIKETVHKLLRRLHL-MPFKDRATSMcSYGTKRKLSTALA 2406
Cdd:COG3845     87 QHFMLV------PNL----TVAENIVLGLeptKGGRLDRKAARARIRELSERYGLdVDPDAKVEDL-SVGEQQRVEILKA 155
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 2407 LIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:COG3845    156 LYRGARILILDEPTAVLTPQEADELFEILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRGK 218
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
2262-2468 8.21e-16

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 80.31  E-value: 8.21e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLIHKkiiAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrnktgsLGHVDSHS---SLVGY 2338
Cdd:PRK15056    12 VTVTWRNGHT---ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISI------LGQPTRQAlqkNLVAY 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2339 CPQEDALD--------DLVTVEE--HLYFYARvhgiPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALI 2408
Cdd:PRK15056    83 VPQSEEVDwsfpvlveDVVMMGRygHMGWLRR----AKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIA 158
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2409 GKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTrLAIMVNG 2468
Cdd:PRK15056   159 QQGQVILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHNLGSVTEFCD-YTVMVKG 217
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
1376-1564 8.31e-16

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 81.69  E-value: 8.31e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1376 ITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGK-----DIKTDLHTVRKNMGVCMQHDVLFSYLTTKEHLLlYGSIKV 1450
Cdd:COG4148     27 VTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEvlqdsARGIFLPPHRRRIGYVFQEARLFPHLSVRGNLL-YGRKRA 105
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1451 PHWTKKQLHEEVKRTLkdtGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK--NK 1528
Cdd:COG4148    106 PRAERRISFDEVVELL---GIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILPYLERlrDE 182
                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 2462571778 1529 TARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:COG4148    183 LDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPL 218
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
1348-1540 9.99e-16

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 79.93  E-value: 9.99e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1348 GVALHGVTKIY-GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLhtvRKNM--G 1424
Cdd:PRK15056     6 GIVVNDVTVTWrNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQAL---QKNLvaY 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1425 VCMQHDVLFSYLTTKEHLLL---YGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSR 1501
Cdd:PRK15056    83 VPQSEEVDWSFPVLVEDVVMmgrYGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQ 162
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2462571778 1502 VVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHL 1540
Cdd:PRK15056   163 VILLDEPFTGVDVKTEARIISLLRElRDEGKTMLVSTHNL 202
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
1358-1564 1.29e-15

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 79.67  E-value: 1.29e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI---KTDLHTVRKNMGVCMQHDVLFS 1434
Cdd:PRK13638    11 YQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLdysKRGLLALRQQVATVFQDPEQQI 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1435 YLTTKEHLLLYgSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDP 1514
Cdd:PRK13638    91 FYTDIDSDIAF-SLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDP 169
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1515 CSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK13638   170 AGRTQMIAIIRRiVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAP 220
cbiO PRK13640
energy-coupling factor transporter ATPase;
1361-1564 1.30e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 79.84  E-value: 1.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1361 KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLF---GASAGTIFVYGKDIKTD-LHTVRKNMGVCMQH-DVLFSY 1435
Cdd:PRK13640    20 KPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLlpdDNPNSKITVDGITLTAKtVWDIREKVGIVFQNpDNQFVG 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 LTTKEHLLlYG--SIKVPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVD 1513
Cdd:PRK13640   100 ATVGDDVA-FGleNRAVP---RPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLD 175
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1514 PCSRRSIWDVISK--NKTARTIILSTHHLDEAEvLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK13640   176 PAGKEQILKLIRKlkKKNNLTVISITHDIDEAN-MADQVLVLDDGKLLAQGSP 227
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
1360-1577 1.31e-15

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 79.67  E-value: 1.31e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1360 SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGkdIKTDLHTV---RKNMGVCMQH-DVLFSY 1435
Cdd:PRK13635    19 ATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGG--MVLSEETVwdvRRQVGMVFQNpDNQFVG 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 lTTKEHLLLYG--SIKVPHwtkKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVD 1513
Cdd:PRK13635    97 -ATVQDDVAFGleNIGVPR---EEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLD 172
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 1514 PCSRRSIWDVIS--KNKTARTIILSTHHLDEAeVLSDRIAFLEQGGLRCCGSPfylKEAFGDGYHL 1577
Cdd:PRK13635   173 PRGRREVLETVRqlKEQKGITVLSITHDLDEA-AQADRVIVMNKGEILEEGTP---EEIFKSGHML 234
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
2274-2479 1.44e-15

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 81.62  E-value: 1.44e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRN----KTGSLGHVDSHSSLVGYCPQEDALDDLV 2349
Cdd:PRK10070    42 LGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGvdiaKISDAELREVRRKKIAMVFQSFALMPHM 121
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2350 TVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKR 2429
Cdd:PRK10070   122 TVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRT 201
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 2430 HLW-KIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:PRK10070   202 EMQdELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEI 252
cbiO PRK13642
energy-coupling factor transporter ATPase;
1358-1623 1.60e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 79.37  E-value: 1.60e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLN---LNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTD-LHTVRKNMGVCMQH-DVL 1432
Cdd:PRK13642    14 YEKESDVNQLNgvsFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAEnVWNLRRKIGMVFQNpDNQ 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1433 FSYLTTKEHLLLygSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGV 1512
Cdd:PRK13642    94 FVGATVEDDVAF--GMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSML 171
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1513 DPCSRRSIWDVIS--KNKTARTIILSTHHLDEAEVlSDRIAFLEQGGLRCCGSPFYLKEAFGDGYHLTLTKKKSPNLNAN 1590
Cdd:PRK13642   172 DPTGRQEIMRVIHeiKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFATSEDMVEIGLDVPFSSNLMKD 250
                          250       260       270
                   ....*....|....*....|....*....|...
gi 2462571778 1591 AVCDTMavtamiqsHLPEAYLKEDiggELVYVL 1623
Cdd:PRK13642   251 LRKNGF--------DLPEKYLSED---ELVELL 272
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
1358-1558 1.60e-15

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 82.87  E-value: 1.60e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVaVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSYl 1436
Cdd:TIGR01193  485 YGSNI-LSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDiDRHTLRQFINYLPQEPYIFSG- 562
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1437 TTKEHLLLYGSIKVPHWTKKQLHE--EVKRTLKD--TGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGV 1512
Cdd:TIGR01193  563 SILENLLLGAKENVSQDEIWAACEiaEIKDDIENmpLGYQTELSEEGSSISGGQKQRIALARALLTDSKVLILDESTSNL 642
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462571778 1513 DPCSRRSIWDVISkNKTARTIILSTHHLDEAEvLSDRIAFLEQGGL 1558
Cdd:TIGR01193  643 DTITEKKIVNNLL-NLQDKTIIFVAHRLSVAK-QSDKIIVLDHGKI 686
cbiO PRK13650
energy-coupling factor transporter ATPase;
1364-1577 1.64e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 79.39  E-value: 1.64e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1364 VDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGK--------DIKTDLHTVRKN-----MGVCMQHD 1430
Cdd:PRK13650    23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDllteenvwDIRHKIGMVFQNpdnqfVGATVEDD 102
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSyLTTKehlllygsiKVPHwtkKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:PRK13650   103 VAFG-LENK---------GIPH---EEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATS 169
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1511 GVDPCSRRSIWDVIS--KNKTARTIILSTHHLDEAeVLSDRIAFLEQGGLRCCGSPfylKEAFGDGYHL 1577
Cdd:PRK13650   170 MLDPEGRLELIKTIKgiRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTP---RELFSRGNDL 234
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
2290-2453 1.66e-15

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 79.28  E-value: 1.66e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2290 GLLGVNGAGKTTIFKMLTGDIIPSSGNILIR------NKTGSLGhVDSHSSLVGYCPQEDALddLVTVEEHLYFYARVHG 2363
Cdd:PRK13638    31 GLVGANGCGKSTLFMNLSGLLRPQKGAVLWQgkpldySKRGLLA-LRQQVATVFQDPEQQIF--YTDIDSDIAFSLRNLG 107
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2364 IPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKC 2443
Cdd:PRK13638   108 VPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIRRIVAQGN 187
                          170
                   ....*....|
gi 2462571778 2444 SVILTSHSME 2453
Cdd:PRK13638   188 HVIISSHDID 197
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
2272-2484 1.71e-15

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 83.25  E-value: 1.71e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2272 KIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIL-----IRNKtgslGHVDSHSSLVGYCPQedALD 2346
Cdd:NF033858    13 KTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEvlggdMADA----RHRRAVCPRIAYMPQ--GLG 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2347 -----DLvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:NF033858    87 knlypTL-SVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTT 165
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2422 GMDPKSKRHLWKIISE--EVQNKCSVILTSHSMEECEAlCTRLAIMVNGKFQCIGSLQHIKSRFG 2484
Cdd:NF033858   166 GVDPLSRRQFWELIDRirAERPGMSVLVATAYMEEAER-FDWLVAMDAGRVLATGTPAELLARTG 229
cbiO PRK13641
energy-coupling factor transporter ATPase;
1361-1573 1.98e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 79.49  E-value: 1.98e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1361 KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTD-----LHTVRKNMGVCMQ--HDVLF 1433
Cdd:PRK13641    20 KKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPEtgnknLKKLRKKVSLVFQfpEAQLF 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1434 SYLTTKEhlLLYGSIKVpHWTKKQLHEEVKRTLKDTGLYSH-RHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGV 1512
Cdd:PRK13641   100 ENTVLKD--VEFGPKNF-GFSEDEAKEKALKWLKKVGLSEDlISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGL 176
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1513 DPCSRRSIWDV-ISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPfylKEAFGD 1573
Cdd:PRK13641   177 DPEGRKEMMQLfKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASP---KEIFSD 235
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
2278-2450 2.23e-15

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 77.15  E-value: 2.23e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVgYCPQEDALDDLVTVEEHLYF 2357
Cdd:PRK13538    19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEYHQDLL-YLGHQPGIKTELTALENLRF 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2358 YARVHGIPEKDikeTVHKLLRRLHLMPFKDRATSMCSYGTKRKlsTALA--LIGKPSILLLDEPSSGMDPKSKRHLWKII 2435
Cdd:PRK13538    98 YQRLHGPGDDE---ALWEALAQVGLAGFEDVPVRQLSAGQQRR--VALArlWLTRAPLWILDEPFTAIDKQGVARLEALL 172
                          170
                   ....*....|....*
gi 2462571778 2436 SEEVQNKCSVILTSH 2450
Cdd:PRK13538   173 AQHAEQGGMVILTTH 187
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
1361-1578 2.58e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 78.91  E-value: 2.58e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1361 KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTI------FVYGKDIKtDLHTVRKNMGVCMQ---HDv 1431
Cdd:PRK13634    20 RRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVtigervITAGKKNK-KLKPLRKKVGIVFQfpeHQ- 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1432 LFSylTTKEHLLLYGSIK--VPhwtKKQLHEEVKRTLKDTGL-YSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:PRK13634    98 LFE--ETVEKDICFGPMNfgVS---EEDAKQKAREMIELVGLpEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEP 172
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1509 STGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPfylKEAFGDGYHLT 1578
Cdd:PRK13634   173 TAGLDPKGRKEMMEMFYKlhKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTP---REIFADPDELE 241
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
1358-1554 2.68e-15

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 78.54  E-value: 2.68e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASA-----GTIFVYGKDI---KTDLHTVRKNMGVCMQH 1429
Cdd:PRK14258    17 YDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESevrveGRVEFFNQNIyerRVNLNRLRRQVSMVHPK 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYLTTKEhlLLYGsIKVPHWTKK-QLHEEVKRTLKDTGLY---SHR-HKRVGTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:PRK14258    97 PNLFPMSVYDN--VAYG-VKIVGWRPKlEIDDIVESALKDADLWdeiKHKiHKSALDLSGGQQQRLCIARALAVKPKVLL 173
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISKN--KTARTIILSTHHLDEAEVLSDRIAFLE 1554
Cdd:PRK14258   174 MDEPCFGLDPIASMKVESLIQSLrlRSELTMVIVSHNLHQVSRLSDFTAFFK 225
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
1340-1556 2.68e-15

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 78.18  E-value: 2.68e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1340 PEPKDLTVG--VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVyGKdikTDLH 1417
Cdd:PRK11247     2 MNTARLNQGtpLLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLA-GT---APLA 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1418 TVRKNMGVCMQHDVLFSYLTTKEH--LLLYGsikvpHWTKKQLheevkRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIA 1495
Cdd:PRK11247    78 EAREDTRLMFQDARLLPWKKVIDNvgLGLKG-----QWRDAAL-----QALAAVGLADRANEWPAALSGGQKQRVALARA 147
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1496 LIGGSRVVILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK11247   148 LIHRPGLLLLDEPLGALDALTRIEMQDLIESlwQQHGFTVLLVTHDVSEAVAMADRVLLIEEG 210
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
1330-1563 3.18e-15

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 81.79  E-value: 3.18e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1330 PEYMFSSNIEPEPKdlTVGVALHGVTKIY--GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFV 1407
Cdd:PRK11160   322 PEVTFPTTSTAAAD--QVSLTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILL 399
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1408 YGKDIKT-DLHTVRKNMGVCMQHDVLFSYlTTKEHLLLygsiKVPHWTKKQLHEevkrTLKDTGLYSHRHKRVG------ 1480
Cdd:PRK11160   400 NGQPIADySEAALRQAISVVSQRVHLFSA-TLRDNLLL----AAPNASDEALIE----VLQQVGLEKLLEDDKGlnawlg 470
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1481 ----TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLsDRIAFLEQG 1556
Cdd:PRK11160   471 eggrQLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQNKTVLMITHRLTGLEQF-DRICVMDNG 549

                   ....*..
gi 2462571778 1557 GLRCCGS 1563
Cdd:PRK11160   550 QIIEQGT 556
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
2275-2470 3.31e-15

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 81.11  E-value: 3.31e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHV-DSHSSLVGYCPQEDALDDLVTVEE 2353
Cdd:PRK11288    19 ALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTtAALAAGVAIIYQELHLVPEMTVAE 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 HLY---FYARVHGIPEKDIKETVHKLLRRLHL-----MPFKDratsmCSYGTKRKLSTALALIGKPSILLLDEPSSGMDP 2425
Cdd:PRK11288    99 NLYlgqLPHKGGIVNRRLLNYEAREQLEHLGVdidpdTPLKY-----LSIGQRQMVEIAKALARNARVIAFDEPTSSLSA 173
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2462571778 2426 KSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKF 2470
Cdd:PRK11288   174 REIEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAITVFKDGRY 218
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
2259-2469 4.29e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 79.12  E-value: 4.29e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2259 LYCLTKTYQliHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRN-----KTGSLGHVDSHS 2333
Cdd:PRK13631    27 LYCVFDEKQ--ENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDiyigdKKNNHELITNPY 104
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2334 --------------SLVGYCPQEDALDDlvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHL-MPFKDRATSMCSYGTK 2398
Cdd:PRK13631   105 skkiknfkelrrrvSMVFQFPEYQLFKD--TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLdDSYLERSPFGLSGGQK 182
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 2399 RKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK13631   183 RRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGK 253
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
1368-1546 4.46e-15

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 76.45  E-value: 4.46e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1368 NLNFY--EGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIktDLHTVRKNMGVCMQHDVLFSYLTTKEHLLLY 1445
Cdd:PRK13539    20 GLSFTlaAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDI--DDPDVAEACHYLGHRNAMKPALTVAENLEFW 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1446 GSIKVPHWTkkqlheEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVIS 1525
Cdd:PRK13539    98 AAFLGGEEL------DIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIR 171
                          170       180
                   ....*....|....*....|....*
gi 2462571778 1526 KN-KTARTIILSTHH---LDEAEVL 1546
Cdd:PRK13539   172 AHlAQGGIVIAATHIplgLPGAREL 196
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
1349-1564 5.93e-15

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 78.97  E-value: 5.93e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDLHTVRKNMGVCMQ 1428
Cdd:PRK10851     3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDV-SRLHARDRKVGFVFQ 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHlLLYGSIKVPHW---TKKQLHEEVKRTLKDTGLySHRHKRVGT-LSGGMKRKLSISIALIGGSRVVI 1504
Cdd:PRK10851    82 HYALFRHMTVFDN-IAFGLTVLPRRerpNAAAIKAKVTQLLEMVQL-AHLADRYPAqLSGGQKQRVALARALAVEPQILL 159
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1505 LDEPSTGVDPCSRRSI--WDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK10851   160 LDEPFGALDAQVRKELrrWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTP 221
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
1352-1564 6.89e-15

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 77.08  E-value: 6.89e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1352 HGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT----DLHTVRknmGVCM 1427
Cdd:COG4559      5 ENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAwspwELARRR---AVLP 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QHDVL-FSYlTTKEHLLLyGSIkvPH-WTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALI-------G 1498
Cdd:COG4559     82 QHSSLaFPF-TVEEVVAL-GRA--PHgSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAqlwepvdG 157
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1499 GSRVVILDEPSTGVDPCSRRSIWDvISKNKTARTI----ILstHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:COG4559    158 GPRWLFLDEPTSALDLAHQHAVLR-LARQLARRGGgvvaVL--HDLNLAAQYADRILLLHQGRLVAQGTP 224
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
1351-1508 7.93e-15

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 80.11  E-value: 7.93e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVyGKDIK----------TDLHTVR 1420
Cdd:COG0488      1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI-PKGLRigylpqepplDDDLTVL 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1421 KNmgVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTK-KQLHEE------------VKRTLKDTGLYSHRH-KRVGTLSGGM 1486
Cdd:COG0488     80 DT--VLDGDAELRALEAELEELEAKLAEPDEDLERlAELQEEfealggweaearAEEILSGLGFPEEDLdRPVSELSGGW 157
                          170       180
                   ....*....|....*....|..
gi 2462571778 1487 KRKLSISIALIGGSRVVILDEP 1508
Cdd:COG0488    158 RRRVALARALLSEPDLLLLDEP 179
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
1350-1547 9.42e-15

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 75.09  E-value: 9.42e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1350 ALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQH 1429
Cdd:TIGR01189    2 AARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEPHENILYLGHL 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYLTTKEHLLLYGSIKVPHwtKKQLHEevkrTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPS 1509
Cdd:TIGR01189   82 PGLKPELSALENLHFWAAIHGGA--QRTIED----ALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPT 155
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 2462571778 1510 TGVDPCSRRSIWDVISKNkTAR--TIILSTHH---LDEAEVLS 1547
Cdd:TIGR01189  156 TALDKAGVALLAGLLRAH-LARggIVLLTTHQdlgLVEARELR 197
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
1343-1575 1.07e-14

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 75.26  E-value: 1.07e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1343 KDLTVGValhgvtkiyGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFG--ASAGTIFVYGKDIkTDLHT-- 1418
Cdd:cd03217      4 KDLHVSV---------GGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKyeVTEGEILFKGEDI-TDLPPee 73
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1419 -VRKNMGVCMQHDVLFSYLTTKEHLllygsikvphwtkkqlheevkrtlkdtglyshRHKRVGtLSGGMKRKLSISIALI 1497
Cdd:cd03217     74 rARLGIFLAFQYPPEIPGVKNADFL--------------------------------RYVNEG-FSGGEKKRNEILQLLL 120
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1498 GGSRVVILDEPSTGVDPCSRRSIWDVISKNKTA-RTIILSTHHLDEAE-VLSDRIAFLEQGGLRCCGSPFYLKEAFGDGY 1575
Cdd:cd03217    121 LEPDLAILDEPDSGLDIDALRLVAEVINKLREEgKSVLIITHYQRLLDyIKPDRVHVLYDGRIVKSGDKELALEIEKKGY 200
cbiO PRK13649
energy-coupling factor transporter ATPase;
1348-1573 1.09e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 77.09  E-value: 1.09e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1348 GVALHGVTKIYGSKV-----AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-----DLH 1417
Cdd:PRK13649     2 GINLQNVSYTYQAGTpfegrALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITStsknkDIK 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1418 TVRKNMGVCMQ--HDVLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEvkrTLKDTGLY-SHRHKRVGTLSGGMKRKLSISI 1494
Cdd:PRK13649    82 QIRKKVGLVFQfpESQLFEETVLKDVAFGPQNFGVSQEEAEALARE---KLALVGISeSLFEKNPFELSGGQMRRVAIAG 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1495 ALIGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPfylKEAFGD 1573
Cdd:PRK13649   159 ILAMEPKILVLDEPTAGLDPKGRKELMTLFKKlHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKP---KDIFQD 235
COG4674 COG4674
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
2275-2481 1.16e-14

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443710 [Multi-domain]  Cd Length: 250  Bit Score: 76.31  E-value: 1.16e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgslghvdshsSLVGYCPQEDA---------- 2344
Cdd:COG4674     25 ALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGT-----------DLTGLDEHEIArlgigrkfqk 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2345 ---LDDLvTVEEHLYF-YARVHGI-------PEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSI 2413
Cdd:COG4674     94 ptvFEEL-TVFENLELaLKGDRGVfaslfarLTAEERDRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIGMLLAQDPKL 172
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2414 LLLDEPSSGMDPKSKRHLWKIIsEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKS 2481
Cdd:COG4674    173 LLLDEPVAGMTDAETERTAELL-KSLAGKHSVVVVEHDMEFVRQIARKVTVLHQGSVLAEGSLDEVQA 239
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
2277-2427 1.25e-14

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 74.59  E-value: 1.25e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2277 NNISIGIPAGECFGLLGVNGAGKTTIFKML----TGDIIpsSGNILIRNKTGslghVDSHSSLVGYCPQEDALDDLVTVE 2352
Cdd:cd03232     24 NNISGYVKPGTLTALMGESGAGKTTLLDVLagrkTAGVI--TGEILINGRPL----DKNFQRSTGYVEQQDVHSPNLTVR 97
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2353 EHLYFYArvhgipekdiketvhkLLRRLhlmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKS 2427
Cdd:cd03232     98 EALRFSA----------------LLRGL-------------SVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQA 143
cbiO PRK13641
energy-coupling factor transporter ATPase;
2274-2469 1.26e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 76.79  E-value: 1.26e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK-----TGS--LGHVDSHSSLVGYCPQEDALD 2346
Cdd:PRK13641    21 KGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYhitpeTGNknLKKLRKKVSLVFQFPEAQLFE 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2347 DlvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHL-------MPFKdratsmCSYGTKRKLSTALALIGKPSILLLDEP 2419
Cdd:PRK13641   101 N--TVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLsedliskSPFE------LSGGQMRRVAIAGVMAYEPEILCLDEP 172
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2420 SSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK13641   173 AAGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGK 222
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
1349-1508 1.43e-14

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 79.34  E-value: 1.43e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIfVYGkdiktdlHTVRknMGVCMQ 1428
Cdd:COG0488    316 LELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTV-KLG-------ETVK--IGYFDQ 385
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 H-DVLFSYLTTKEHLLLYGsikvPHWTKKqlheEVKRTLKDTGLYSHR-HKRVGTLSGGMKRKLSISIALIGGSRVVILD 1506
Cdd:COG0488    386 HqEELDPDKTVLDELRDGA----PGGTEQ----EVRGYLGRFLFSGDDaFKPVGVLSGGEKARLALAKLLLSPPNVLLLD 457

                   ..
gi 2462571778 1507 EP 1508
Cdd:COG0488    458 EP 459
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
2265-2475 1.56e-14

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 75.96  E-value: 1.56e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2265 TYQLIHKKIIavNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSH--SSLVGYCPQE 2342
Cdd:PRK13548     9 SVRLGGRTLL--DDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGR--PLADWSPAelARRRAVLPQH 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2343 DALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRK--LSTALALI----GKPSILLL 2416
Cdd:PRK13548    85 SSLSFPFTVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRvqLARVLAQLwepdGPPRWLLL 164
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2417 DEPSSGMDPKSKRHLWKIISE-EVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGS 2475
Cdd:PRK13548   165 DEPTSALDLAHQHHVLRLARQlAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGT 224
cbiO PRK13640
energy-coupling factor transporter ATPase;
2275-2456 1.63e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 76.38  E-value: 1.63e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIP-----SSGNIL-----------IRNKTGSLGHvDSHSSLVGy 2338
Cdd:PRK13640    22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPddnpnSKITVDgitltaktvwdIREKVGIVFQ-NPDNQFVG- 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2339 cpqedalddlVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDE 2418
Cdd:PRK13640   100 ----------ATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDE 169
                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 2462571778 2419 PSSGMDPKSKRHLWKIISE-EVQNKCSVILTSHSMEECE 2456
Cdd:PRK13640   170 STSMLDPAGKEQILKLIRKlKKKNNLTVISITHDIDEAN 208
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
1352-1564 2.06e-14

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 75.58  E-value: 2.06e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1352 HGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIK----TDLHTVRknmGVCM 1427
Cdd:PRK13548     6 RNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLAdwspAELARRR---AVLP 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QHDVL-FSYlTTKEHLLLYGSikvPH-WTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALI------GG 1499
Cdd:PRK13548    83 QHSSLsFPF-TVEEVVAMGRA---PHgLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGP 158
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1500 SRVVILDEPSTGVDPCSRRSIWDvISKNKTART-----IILstHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:PRK13548   159 PRWLLLDEPTSALDLAHQHHVLR-LARQLAHERglaviVVL--HDLNLAARYADRIVLLHQGRLVADGTP 225
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
1351-1558 2.87e-14

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 73.02  E-value: 2.87e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYG--SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCM 1427
Cdd:cd03246      3 VENVSFRYPgaEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQwDPNELGDHVGYLP 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 QHDVLFSylttkehlllyGSIkvphwtkkqlheevkrtlkdtglyshrhkRVGTLSGGMKRKLSISIALIGGSRVVILDE 1507
Cdd:cd03246     83 QDDELFS-----------GSI-----------------------------AENILSGGQRQRLGLARALYGNPRILVLDE 122
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1508 PSTGVDPCSRRSIWDVISKNKTAR-TIILSTHHLdeaEVLS--DRIAFLEQGGL 1558
Cdd:cd03246    123 PNSHLDVEGERALNQAIAALKAAGaTRIVIAHRP---ETLAsaDRILVLEDGRV 173
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
2274-2469 4.13e-14

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 74.74  E-value: 4.13e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK----------TGSLGHV--DShssLVGYCPq 2341
Cdd:COG1101     20 RALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKdvtklpeykrAKYIGRVfqDP---MMGTAP- 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 edaldDLvTVEEHLYF-YARVH------GIPEKDIKEtVHKLLRRLHLmPFKDR---ATSMCSYGTKRKLSTALALIGKP 2411
Cdd:COG1101     96 -----SM-TIEENLALaYRRGKrrglrrGLTKKRREL-FRELLATLGL-GLENRldtKVGLLSGGQRQALSLLMATLTKP 167
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2412 SILLLDEPSSGMDPKSKRHLW----KIISEevqNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:COG1101    168 KLLLLDEHTAALDPKTAALVLelteKIVEE---NNLTTLMVTHNMEQALDYGNRLIMMHEGR 226
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
2272-2469 4.99e-14

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 74.15  E-value: 4.99e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2272 KIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK------TGSLGHVDshsslVGYCPQEDAL 2345
Cdd:PRK11614    17 KIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKditdwqTAKIMREA-----VAIVPEGRRV 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2346 DDLVTVEEHLY---FYARVHGIPEKdiKETVHKLLRRLHLMPFKdRATSMcSYGTKRKLSTALALIGKPSILLLDEPSSG 2422
Cdd:PRK11614    92 FSRMTVEENLAmggFFAERDQFQER--IKWVYELFPRLHERRIQ-RAGTM-SGGEQQMLAIGRALMSQPRLLLLDEPSLG 167
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2462571778 2423 MDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK11614   168 LAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGH 214
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
2275-2453 8.31e-14

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 76.94  E-value: 8.31e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDDlVTVEEH 2354
Cdd:TIGR02857  337 ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQIAWVPQHPFLFA-GTIAEN 415
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 LYFYARvhGIPEKDIKETVHK---------LLRRLHLMpfKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDP 2425
Cdd:TIGR02857  416 IRLARP--DASDAEIREALERagldefvaaLPQGLDTP--IGEGGAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDA 491
                          170       180
                   ....*....|....*....|....*...
gi 2462571778 2426 KSKRHLWKIISEEVQNKcSVILTSHSME 2453
Cdd:TIGR02857  492 ETEAEVLEALRALAQGR-TVLLVTHRLA 518
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
2262-2469 8.71e-14

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 70.94  E-value: 8.71e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYqliHKKIIaVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGnILIRNKTGSLGHVdshsslvgycpq 2341
Cdd:cd03221      6 LSKTY---GGKLL-LKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEG-IVTWGSTVKIGYF------------ 68
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 edalddlvtveEHLyfyarvhgipekdiketvhkllrrlhlmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:cd03221     69 -----------EQL--------------------------------------SGGEKMRLALAKLLLENPNLLLLDEPTN 99
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 2422 GMDPKSKRHLwkiiSEEVQN-KCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03221    100 HLDLESIEAL----EEALKEyPGTVILVSHDRYFLDQVATKIIELEDGK 144
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
2256-2488 9.00e-14

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 76.79  E-value: 9.00e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2256 LVQLYCLTKTYqlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGdIIPS---SGNILIRNKTGSLGHV-DS 2331
Cdd:TIGR02633    1 LLEMKGIVKTF----GGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSG-VYPHgtwDGEIYWSGSPLKASNIrDT 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2332 HSSLVGYCPQEDALDDLVTVEEHLYFYARV-HGIPEKDIKETV---HKLLRRLHLMPFKD-RATSMCSYGTKRKLSTALA 2406
Cdd:TIGR02633   76 ERAGIVIIHQELTLVPELSVAENIFLGNEItLPGGRMAYNAMYlraKNLLRELQLDADNVtRPVGDYGGGQQQLVEIAKA 155
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2407 LIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGkfqcigslQHIKSRFGRG 2486
Cdd:TIGR02633  156 LNKQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDG--------QHVATKDMST 227

                   ..
gi 2462571778 2487 FT 2488
Cdd:TIGR02633  228 MS 229
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
1363-1556 1.06e-13

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 71.69  E-value: 1.06e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCM-----QHDVLFSYLT 1437
Cdd:cd03215     15 AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAIRAGIAYvpedrKREGLVLDLS 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1438 TKEHLLLygsikvphwtkKQLheevkrtlkdtglyshrhkrvgtLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSR 1517
Cdd:cd03215     95 VAENIAL-----------SSL-----------------------LSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAK 140
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2462571778 1518 RSIWDVISKNKTA-RTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:cd03215    141 AEIYRLIRELADAgKAVLLISSELDELLGLCDRILVMYEG 180
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
2273-2488 1.12e-13

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 76.51  E-value: 1.12e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2273 IIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGdIIPS---SGNILIRNKTGSLGHV-DSHSSLVGYCPQEDALDDL 2348
Cdd:PRK13549    18 VKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSG-VYPHgtyEGEIIFEGEELQASNIrDTERAGIAIIHQELALVKE 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2349 VTVEEHLYFYARV--HGIPEKD-IKETVHKLLRRLHLmpFKDRATSMCSYGT-KRKL-STALALIGKPSILLLDEPSSGM 2423
Cdd:PRK13549    97 LSVLENIFLGNEItpGGIMDYDaMYLRAQKLLAQLKL--DINPATPVGNLGLgQQQLvEIAKALNKQARLLILDEPTASL 174
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2424 DPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKfqcigslqHIKSRFGRGFT 2488
Cdd:PRK13549   175 TESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGR--------HIGTRPAAGMT 231
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
1304-1556 1.15e-13

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 76.68  E-value: 1.15e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1304 KPEKSngLMFTNIMMQNTNPSAsktspEYMFSS-NIEPEPKDLTVG-------VALHGVTKIYG--SKVAVDNLNLNFYE 1373
Cdd:TIGR02203  285 RPLKS--LTNVNAPMQRGLAAA-----ESLFTLlDSPPEKDTGTRAierargdVEFRNVTFRYPgrDRPALDSISLVIEP 357
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1374 GHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSylTTKEHLLLYGSikvph 1452
Cdd:TIGR02203  358 GETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADyTLASLRRQVALVSQDVVLFN--DTIANNIAYGR----- 430
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1453 wTKKQLHEEVKRTLKDTGLYSH-------RHKRVGT----LSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIW 1521
Cdd:TIGR02203  431 -TEQADRAEIERALAAAYAQDFvdklplgLDTPIGEngvlLSGGQRQRLAIARALLKDAPILILDEATSALDNESERLVQ 509
                          250       260       270
                   ....*....|....*....|....*....|....*
gi 2462571778 1522 DVISKNKTARTIILSTHHLDEAEVlSDRIAFLEQG 1556
Cdd:TIGR02203  510 AALERLMQGRTTLVIAHRLSTIEK-ADRIVVMDDG 543
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
1351-1556 1.18e-13

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 76.40  E-value: 1.18e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLF--GASAGTIFVYGKDIKTD--LHTVRKNMGVC 1426
Cdd:TIGR02633    4 MKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYphGTWDGEIYWSGSPLKASniRDTERAGIVII 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 MQHDVLFSYLTTKEHLLLYGSIKVP----HWTKKQLH-EEVKRTLKDTGLYSHRhkRVGTLSGGMKRKLSISIALIGGSR 1501
Cdd:TIGR02633   84 HQELTLVPELSVAENIFLGNEITLPggrmAYNAMYLRaKNLLRELQLDADNVTR--PVGDYGGGQQQLVEIAKALNKQAR 161
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1502 VVILDEPSTGVDPCSRRSIWDVIsKNKTARTI--ILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:TIGR02633  162 LLILDEPSSSLTEKETEILLDII-RDLKAHGVacVYISHKLNEVKAVCDTICVIRDG 217
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
2271-2479 1.33e-13

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 73.31  E-value: 1.33e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2271 KKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIlirNKTGSLGHVDSHSSLVGYcpqedalddlVT 2350
Cdd:PRK13546    35 KTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKV---DRNGEVSVIAISAGLSGQ----------LT 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2351 VEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEP-SSGMDPKSKR 2429
Cdd:PRK13546   102 GIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEAlSVGDQTFAQK 181
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2430 HLWKIISEEVQNKcSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:PRK13546   182 CLDKIYEFKEQNK-TIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDV 230
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
2275-2469 1.54e-13

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 75.83  E-value: 1.54e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHV-DSHSSLVGYCPQEDALDDLV---T 2350
Cdd:COG1129    267 VVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPrDAIRAGIAYVPEDRKGEGLVldlS 346
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2351 VEEHLYF-----YARVHGIPEKDIKETVHKLLRRLHLmpfkdRATSMcsyGTK-RKLS------TALA--LIGKPSILLL 2416
Cdd:COG1129    347 IRENITLasldrLSRGGLLDRRRERALAEEYIKRLRI-----KTPSP---EQPvGNLSggnqqkVVLAkwLATDPKVLIL 418
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 2417 DEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:COG1129    419 DEPTRGIDVGAKAEIYRLIRELAAEGKAVIVISSELPELLGLSDRILVMREGR 471
cbiO PRK13642
energy-coupling factor transporter ATPase;
2276-2469 1.77e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 73.20  E-value: 1.77e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQE-DALDDLVTVEEH 2354
Cdd:PRK13642    23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLRRKIGMVFQNpDNQFVGATVEDD 102
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 LYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKI 2434
Cdd:PRK13642   103 VAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRV 182
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2462571778 2435 IsEEVQNK--CSVILTSHSMEECeALCTRLAIMVNGK 2469
Cdd:PRK13642   183 I-HEIKEKyqLTVLSITHDLDEA-ASSDRILVMKAGE 217
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
2278-2469 2.15e-13

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 72.09  E-value: 2.15e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSH----SSLVgycpQEDALDDLVTVEE 2353
Cdd:COG3840     17 RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQ--DLTALPPAerpvSMLF----QENNLFPHLTVAQ 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 HLYFyarvhGI-----PEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSK 2428
Cdd:COG3840     91 NIGL-----GLrpglkLTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPALR 165
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 2462571778 2429 R---HLWKIISEEVQNkcSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:COG3840    166 QemlDLVDELCRERGL--TVLMVTHDPEDAARIADRVLLVADGR 207
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
2275-2488 2.30e-13

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 72.42  E-value: 2.30e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgslghVDSHSSLVGYCPQEDALDDLVTVEEH 2354
Cdd:PRK11248    16 ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKP-----VEGPGAERGVVFQNEGLLPWRNVQDN 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 LYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRH---- 2430
Cdd:PRK11248    91 VAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQmqtl 170
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2431 LWKIISEEVQnkcSVILTSHSMEECEALCTRLAIMVNGKFQCigsLQHIKSRFGRGFT 2488
Cdd:PRK11248   171 LLKLWQETGK---QVLLITHDIEEAVFMATELVLLSPGPGRV---VERLPLNFARRFV 222
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
1363-1567 2.58e-13

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 72.02  E-value: 2.58e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGA----SAGTIFVYGKDIkTDLHTVRKNMGVCMQH--DVLFSYL 1436
Cdd:TIGR02770    1 LVQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPgltqTSGEILLDGRPL-LPLSIRGRHIATIMQNprTAFNPLF 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1437 TTKEH----LLLYGSI-KVPhwTKKQLH-------EEVKRTLKdtgLYSHRhkrvgtLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:TIGR02770   80 TMGNHaietLRSLGKLsKQA--RALILEaleavglPDPEEVLK---KYPFQ------LSGGMLQRVMIALALLLEPPFLI 148
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYL 1567
Cdd:TIGR02770  149 ADEPTTDLDVVNQARVLKLLRElrQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEI 213
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
1359-1539 3.56e-13

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 70.60  E-value: 3.56e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1359 GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTT 1438
Cdd:cd03231     11 DGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLLYLGHAPGIKTTLSV 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1439 KEHLLLYGSIkvpHWTkkqlhEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRR 1518
Cdd:cd03231     91 LENLRFWHAD---HSD-----EQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVA 162
                          170       180
                   ....*....|....*....|...
gi 2462571778 1519 SIWDVISKNkTAR--TIILSTHH 1539
Cdd:cd03231    163 RFAEAMAGH-CARggMVVLTTHQ 184
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
2262-2483 3.60e-13

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 71.97  E-value: 3.60e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQliHKKiiAVNNISIGIPAGECFGLLGVNGAGKTTIFK----MLTGDIIPSSGNILIRN---KTGSL-GHVDSHS 2333
Cdd:PRK09984    10 LAKTFN--QHQ--ALHAVDLNIHHGEMVALLGPSGSGKSTLLRhlsgLITGDKSAGSHIELLGRtvqREGRLaRDIRKSR 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2334 SLVGYCPQEDALDDLVTVEEHLY--------FYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTAL 2405
Cdd:PRK09984    86 ANTGYIFQQFNLVNRLSVLENVLigalgstpFWRTCFSWFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAIAR 165
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2406 ALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNK-CSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKS-RF 2483
Cdd:PRK09984   166 ALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDgITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQFDNeRF 245
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
2271-2446 3.82e-13

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 71.10  E-value: 3.82e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2271 KKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDAL--Ddl 2348
Cdd:cd03254     14 EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSMIGVVLQDTFLfsG-- 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2349 vTVEEHLYFyarvhGIPEKDiKETVHKLLRRLHLMPF-----KDRATSM------CSYGTKRKLSTALALIGKPSILLLD 2417
Cdd:cd03254     92 -TIMENIRL-----GRPNAT-DEEVIEAAKEAGAHDFimklpNGYDTVLgenggnLSQGERQLLAIARAMLRDPKILILD 164
                          170       180
                   ....*....|....*....|....*....
gi 2462571778 2418 EPSSGMDPKSKRHLWKIISEEVQNKCSVI 2446
Cdd:cd03254    165 EATSNIDTETEKLIQEALEKLMKGRTSII 193
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
2270-2448 4.67e-13

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 71.11  E-value: 4.67e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2270 HKKIIavNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDAL-DDl 2348
Cdd:cd03253     13 GRPVL--KDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRAIGVVPQDTVLfND- 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2349 vTVEEHLYfYARVHGIPEKDIKET----VHKLLRRlhlMPFK------DRATsMCSYGTKRKLSTALALIGKPSILLLDE 2418
Cdd:cd03253     90 -TIGYNIR-YGRPDATDEEVIEAAkaaqIHDKIMR---FPDGydtivgERGL-KLSGGEKQRVAIARAILKNPPILLLDE 163
                          170       180       190
                   ....*....|....*....|....*....|
gi 2462571778 2419 PSSGMDPKSKRHLWKIISEEVQNKCSVILT 2448
Cdd:cd03253    164 ATSALDTHTEREIQAALRDVSKGRTTIVIA 193
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
1350-1556 4.83e-13

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 74.18  E-value: 4.83e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1350 ALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQH 1429
Cdd:PRK11288     6 SFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAALAAGVAIIY 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVL--FSYLTTKEHLLL------YGSIKvphwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSR 1501
Cdd:PRK11288    86 QELhlVPEMTVAENLYLgqlphkGGIVN-----RRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNAR 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1502 VVILDEPSTGVdpcSRRSI---WDVISKNKT-ARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK11288   161 VIAFDEPTSSL---SAREIeqlFRVIRELRAeGRVILYVSHRMEEIFALCDAITVFKDG 216
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
2274-2516 5.04e-13

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 72.36  E-value: 5.04e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI---------RNKtgSLGHVDSHSSLVGYCPQEDA 2344
Cdd:PRK13634    21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIgervitagkKNK--KLKPLRKKVGIVFQFPEHQL 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2345 LDDlvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMP-FKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGM 2423
Cdd:PRK13634    99 FEE--TVEKDICFGPMNFGVSEEDAKQKAREMIELVGLPEeLLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGL 176
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2424 DPKSKRHLWKIISEEVQNK-CSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIksrfgrgFTVKVHLKNNKVTMET 2502
Cdd:PRK13634   177 DPKGRKEMMEMFYKLHKEKgLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREI-------FADPDELEAIGLDLPE 249
                          250       260
                   ....*....|....*....|.
gi 2462571778 2503 LTKFMQ-------LHFPKTYL 2516
Cdd:PRK13634   250 TVKFKRaleekfgISFPKPCL 270
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
1353-1556 5.16e-13

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 74.20  E-value: 5.16e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLF--GASAGTIFVYGKDIK--TDLHTVRKNMGVCMQ 1428
Cdd:PRK13549    10 NITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYphGTYEGEIIFEGEELQasNIRDTERAGIAIIHQ 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTTKEHLLLyGSIKVPH----WTKkqLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:PRK13549    90 ELALVKELSVLENIFL-GNEITPGgimdYDA--MYLRAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQARLLI 166
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVIS--KNKTARTIILStHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK13549   167 LDEPTASLTESETAVLLDIIRdlKAHGIACIYIS-HKLNEVKAISDTICVIRDG 219
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
1358-1558 5.54e-13

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 72.05  E-value: 5.54e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAG-----TIFVYGKDI--KTDLHTVRKNMGVCMQHD 1430
Cdd:PRK14271    31 FAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGGRSIfnYRDVLEFRRRVGMLFQRP 110
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSyLTTKEHLL--LYGSIKVPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGT----LSGGMKRKLSISIALIGGSRVVI 1504
Cdd:PRK14271   111 NPFP-MSIMDNVLagVRAHKLVP---RKEFRGVAQARLTEVGLWDAVKDRLSDspfrLSGGQQQLLCLARTLAVNPEVLL 186
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGL 1558
Cdd:PRK14271   187 LDEPTSALDPTTTEKIEEFIRSLADRLTVIIVTHNLAQAARISDRAALFFDGRL 240
ABC2_membrane_3 pfam12698
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ...
1026-1270 5.96e-13

ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.


Pssm-ID: 463674 [Multi-domain]  Cd Length: 345  Bit Score: 72.81  E-value: 5.96e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1026 DSIERAIIELQTGrNSQEIAVQVQAIPYPCFMKDNFLTSVSYSL-PIVLMVAWVVFIAAFVKKLVYEKDLRLHEYMKMMG 1104
Cdd:pfam12698  121 QSLLQQLNASALV-LLLEALSTSAPIPVESTPLFNPQSGYAYYLvGLILMIIILIGAAIIAVSIVEEKESRIKERLLVSG 199
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1105 VNSCSHFFAWLIeSVGFLLVTIVILIIILKFGNILPKTNGFILFLYFSDYSFSVIAMSYLISVFFNNTNIAALIGSLIYI 1184
Cdd:pfam12698  200 VSPLQYWLGKIL-GDFLVGLLQLLIILLLLFGIGIPFGNLGLLLLLFLLYGLAYIALGYLLGSLFKNSEDAQSIIGIVIL 278
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1185 IAFFPFIVLVTVENeLSYVLKVFMSLLSPTAFsyasqyiaryeeqGIGLQWENMYTSPVQdDTTSFGWLCCLILadsfIY 1264
Cdd:pfam12698  279 LLSGFFGGLFPLED-PPSFLQWIFSIIPFFSP-------------IDGLLRLIYGDSLWE-IAPSLIILLLFAV----VL 339

                   ....*.
gi 2462571778 1265 FLIAWY 1270
Cdd:pfam12698  340 LLLALL 345
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
2277-2450 9.58e-13

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 73.93  E-value: 9.58e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2277 NNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPS---SGNILIRnktgslGHV---DSHSSLVGYCPQEDALDDLVT 2350
Cdd:TIGR00955   42 KNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLN------GMPidaKEMRAISAYVQQDDLFIPTLT 115
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2351 VEEHLYFYARVH---GIPEKDIKETVHKLLRRLHLMPFKD-------RATSMcSYGTKRKLSTALALIGKPSILLLDEPS 2420
Cdd:TIGR00955  116 VREHLMFQAHLRmprRVTKKEKRERVDEVLQALGLRKCANtrigvpgRVKGL-SGGERKRLAFASELLTDPPLLFCDEPT 194
                          170       180       190
                   ....*....|....*....|....*....|
gi 2462571778 2421 SGMDPKSKRHLWKIISEEVQNKCSVILTSH 2450
Cdd:TIGR00955  195 SGLDSFMAYSVVQVLKGLAQKGKTIICTIH 224
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
1366-1556 1.22e-12

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 73.16  E-value: 1.22e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1366 NLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCM-----QHDVLF--SYLTT 1438
Cdd:PRK15439   281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQRLARGLVYlpedrQSSGLYldAPLAW 360
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1439 KEHLLLYGsiKVPHWTK-KQLHEEVKRTLKDTGL-YSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCS 1516
Cdd:PRK15439   361 NVCALTHN--RRGFWIKpARENAVLERYRRALNIkFNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSA 438
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 2462571778 1517 RRSIWDVI---SKNKTArtIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK15439   439 RNDIYQLIrsiAAQNVA--VLFISSDLEEIEQMADRVLVMHQG 479
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
1349-1556 1.39e-12

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 70.16  E-value: 1.39e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTD---------LHTV 1419
Cdd:PRK11264     4 IEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIDTArslsqqkglIRQL 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1420 RKNMGVCMQHDVLFSYLTTKEHLllygsIKVPHWTKKQLHEEV----KRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIA 1495
Cdd:PRK11264    84 RQHVGFVFQNFNLFPHRTVLENI-----IEGPVIVKGEPKEEAtaraRELLAKVGLAGKETSYPRRLSGGQQQRVAIARA 158
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1496 LIGGSRVVILDEPSTGVDPCSRRSIWDVI-SKNKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK11264   159 LAMRPEVILFDEPTSALDPELVGEVLNTIrQLAQEKRTMVIVTHEMSFARDVADRAIFMDQG 220
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
2276-2469 1.91e-12

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 72.34  E-value: 1.91e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgslghvdshssLVGYCPQeDAL---------- 2345
Cdd:PRK10762   268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHE-----------VVTRSPQ-DGLangivyised 335
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2346 ---DDLV---TVEEHL------YFYARVHGIPEKDIKETVHKLLRRLHL-MPFKDRATSMCSYGTKRKLSTALALIGKPS 2412
Cdd:PRK10762   336 rkrDGLVlgmSVKENMsltalrYFSRAGGSLKHADEQQAVSDFIRLFNIkTPSMEQAIGLLSGGNQQKVAIARGLMTRPK 415
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 2413 ILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK10762   416 VLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGR 472
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
2262-2469 1.96e-12

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 69.66  E-value: 1.96e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQlihKKIIaVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSH--SSLVGYC 2339
Cdd:PRK11231     8 LTVGYG---TKRI-LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDK--PISMLSSRqlARRLALL 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2340 PQEDALDDLVTVEE--------HLYFYARvhgIPEKDiKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKP 2411
Cdd:PRK11231    82 PQHHLTPEGITVRElvaygrspWLSLWGR---LSAED-NARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDT 157
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2412 SILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK11231   158 PVVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGH 215
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
2275-2470 2.40e-12

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 71.96  E-value: 2.40e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSL-GHVDSHSSLVGYCPQEDALDDLVTVEE 2353
Cdd:PRK10762    19 ALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFnGPKSSQEAGIGIIHQELNLIPQLTIAE 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 HLY----FYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKR 2429
Cdd:PRK10762    99 NIFlgreFVNRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPTDALTDTETE 178
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 2462571778 2430 HLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKF 2470
Cdd:PRK10762   179 SLFRVIRELKSQGRGIVYISHRLKEIFEICDDVTVFRDGQF 219
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
1351-1556 2.92e-12

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 69.09  E-value: 2.92e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTV---------R 1420
Cdd:TIGR02323    6 VSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSGAElELYQLseaerrrlmR 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1421 KNMGVCMQH--DVLFSYLTT----KEHLLL-----YGSIKVP--HWTKKQlheEVKRTLKDtglyshrhKRVGTLSGGMK 1487
Cdd:TIGR02323   86 TEWGFVHQNprDGLRMRVSAganiGERLMAigarhYGNIRATaqDWLEEV---EIDPTRID--------DLPRAFSGGMQ 154
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1488 RKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:TIGR02323  155 QRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGlvRDLGLAVIIVTHDLGVARLLAQRLLVMQQG 225
cbiO PRK13649
energy-coupling factor transporter ATPase;
2275-2469 3.35e-12

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 69.39  E-value: 3.35e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI-------RNKTGSLGHVDSHSSLVGYCPQEDALDD 2347
Cdd:PRK13649    22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVddtlitsTSKNKDIKQIRKKVGLVFQFPESQLFEE 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2348 lvTVEEHLYFYARVHGIPekdiKETVHKLLR-RLHLM----PFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSG 2422
Cdd:PRK13649   102 --TVLKDVAFGPQNFGVS----QEEAEALAReKLALVgiseSLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAG 175
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2462571778 2423 MDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK13649   176 LDPKGRKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGK 222
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
2274-2431 3.91e-12

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 71.62  E-value: 3.91e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDDlVTVEE 2353
Cdd:TIGR02868  349 PVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRRVSVCAQDAHLFD-TTVRE 427
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 HLYFyarvhGIPEKDiKETVHKLLRRLHLMPFKDR-----ATSM------CSYGTKRKLSTALALIGKPSILLLDEPSSG 2422
Cdd:TIGR02868  428 NLRL-----ARPDAT-DEELWAALERVGLADWLRAlpdglDTVLgeggarLSGGERQRLALARALLADAPILLLDEPTEH 501

                   ....*....
gi 2462571778 2423 MDPKSKRHL 2431
Cdd:TIGR02868  502 LDAETADEL 510
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
1358-1564 3.93e-12

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 68.57  E-value: 3.93e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKdIKTDLhtvrkNMGVCMQHDvlfsyLT 1437
Cdd:COG1134     36 REEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGR-VSALL-----ELGAGFHPE-----LT 104
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1438 TKEHLLLYGSIkvphwtkkqL---HEEVKRTLKD----TGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP-S 1509
Cdd:COG1134    105 GRENIYLNGRL---------LglsRKEIDEKFDEivefAELGDFIDQPVKTYSSGMRARLAFAVATAVDPDILLVDEVlA 175
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1510 TGvDP-----CSRRsIWDVISKnktARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:COG1134    176 VG-DAafqkkCLAR-IRELRES---GRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDP 230
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
2283-2462 5.01e-12

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 67.57  E-value: 5.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2283 IPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDAldDLVTVeEHLYFYARVH 2362
Cdd:PRK13543    34 VDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGDRSRFMAYLGHLPGLKA--DLSTL-ENLHFLCGLH 110
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2363 GipeKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNK 2442
Cdd:PRK13543   111 G---RRAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMISAHLRGG 187
                          170       180
                   ....*....|....*....|
gi 2462571778 2443 CSVILTSHSMEECEALCTRL 2462
Cdd:PRK13543   188 GAALVTTHGAYAAPPVRTRM 207
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
2277-2469 5.41e-12

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 67.11  E-value: 5.41e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2277 NNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIlirnktgslghvdSHSSLVGYCPQE----DAlddlvTVE 2352
Cdd:cd03250     22 KDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSV-------------SVPGSIAYVSQEpwiqNG-----TIR 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2353 EHLYFyarvhGIP--EKDIKETVHK--LLRRLHLMPFKD------RATSMcSYGTKRKLSTALALIGKPSILLLDEPSSG 2422
Cdd:cd03250     84 ENILF-----GKPfdEERYEKVIKAcaLEPDLEILPDGDlteigeKGINL-SGGQKQRISLARAVYSDADIYLLDDPLSA 157
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 2423 MDPKSKRHLWK--IISEEVQNKCsVILTSHSMEECEAlCTRLAIMVNGK 2469
Cdd:cd03250    158 VDAHVGRHIFEncILGLLLNNKT-RILVTHQLQLLPH-ADQIVVLDNGR 204
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
1363-1551 7.94e-12

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 70.43  E-value: 7.94e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKtdLHTV--------------RKNMGVCMQ 1428
Cdd:COG1129    267 VVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVR--IRSPrdairagiayvpedRKGEGLVLD 344
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLF-SYLTTKEHLLLYGSIKvphwtKKQLHEEVKRTLKDTGL-YSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILD 1506
Cdd:COG1129    345 LSIREnITLASLDRLSRGGLLD-----RRRERALAEEYIKRLRIkTPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILD 419
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 1507 EPSTGVDPCSRRSIWDVIskNKTAR---TIILSTHHLDEAEVLSDRIA 1551
Cdd:COG1129    420 EPTRGIDVGAKAEIYRLI--RELAAegkAVIVISSELPELLGLSDRIL 465
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
1379-1551 8.55e-12

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 67.30  E-value: 8.55e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1379 LLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDiktdlHT----VRKNMGVCMQHDVLFSYLTTKEH--LLLYGSIKVPH 1452
Cdd:PRK10771    30 ILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQD-----HTttppSRRPVSMLFQENNLFSHLTVAQNigLGLNPGLKLNA 104
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1453 WTKKQLHEEVKRtlkdTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTAR- 1531
Cdd:PRK10771   105 AQREKLHAIARQ----MGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVCQERq 180
                          170       180
                   ....*....|....*....|.
gi 2462571778 1532 -TIILSTHHLDEAEvlsdRIA 1551
Cdd:PRK10771   181 lTLLMVSHSLEDAA----RIA 197
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
7-86 1.00e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 71.20  E-value: 1.00e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778    7 QLQILVWKNWLGVKRQPLWTLVLILWPVIIFIILAITRTKFPPTAKPTCYLAPRNLPSTGFFPFLQTLLCDTDSKCKDTP 86
Cdd:TIGR01257    6 QIQLLLWKNWTLRKRQKIRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCFQSP 85
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
2276-2452 1.02e-11

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 67.45  E-value: 1.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIlirnktgslghVDSHSSLVGYCPQEDALDDL--VTVEE 2353
Cdd:PRK09544    20 LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI-----------KRNGKLRIGYVPQKLYLDTTlpLTVNR 88
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 HLyfyaRVH-GIPEKDIKETvhklLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLW 2432
Cdd:PRK09544    89 FL----RLRpGTKKEDILPA----LKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY 160
                          170       180
                   ....*....|....*....|..
gi 2462571778 2433 KIIsEEVQNK--CSVILTSHSM 2452
Cdd:PRK09544   161 DLI-DQLRREldCAVLMVSHDL 181
cbiO PRK13643
energy-coupling factor transporter ATPase;
2275-2454 1.22e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 68.22  E-value: 1.22e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI-------RNKTGSLGHVDSHSSLVGYCPQEDALDD 2347
Cdd:PRK13643    21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVgdivvssTSKQKEIKPVRKKVGVVFQFPESQLFEE 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2348 lvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHL-MPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPK 2426
Cdd:PRK13643   101 --TVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLaDEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPK 178
                          170       180
                   ....*....|....*....|....*...
gi 2462571778 2427 SKRHLWKIISEEVQNKCSVILTSHSMEE 2454
Cdd:PRK13643   179 ARIEMMQLFESIHQSGQTVVLVTHLMDD 206
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
2275-2506 1.64e-11

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 69.53  E-value: 1.64e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRnktGSlghvdshSSLVGYcpqEDALDDLVTVEEH 2354
Cdd:PRK13545    39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIK---GS-------AALIAI---SSGLNGQLTGIEN 105
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 LYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKI 2434
Cdd:PRK13545   106 IELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLDK 185
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 2435 ISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKSRFGRgftvkvHLKN-NKVTMETLTKF 2506
Cdd:PRK13545   186 MNEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDHYDE------FLKKyNQMSVEERKDF 252
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
1379-1564 2.00e-11

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 65.90  E-value: 2.00e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1379 LLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSYlTTKEHLLLYGsikvpHWTKKQ 1457
Cdd:cd03369     39 IVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTiPLEDLRSSLTIIPQDPTLFSG-TIRSNLDPFD-----EYSDEE 112
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1458 LHEEVKrtLKDTGLyshrhkrvgTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILST 1537
Cdd:cd03369    113 IYGALR--VSEGGL---------NLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIREEFTNSTILTIA 181
                          170       180
                   ....*....|....*....|....*..
gi 2462571778 1538 HHLdEAEVLSDRIAFLEQGGLRCCGSP 1564
Cdd:cd03369    182 HRL-RTIIDYDKILVMDAGEVKEYDHP 207
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
1358-1539 2.08e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 65.74  E-value: 2.08e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1358 YGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLT 1437
Cdd:PRK13540    11 YHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDLCTYQKQLCFVGHRSGINPYLT 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1438 TKEHLLLYgsikvPHWTKKQLH-EEVKRTLKdtgLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDpcs 1516
Cdd:PRK13540    91 LRENCLYD-----IHFSPGAVGiTELCRLFS---LEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALD--- 159
                          170       180
                   ....*....|....*....|....*..
gi 2462571778 1517 RRSIWDVISKNKTAR----TIILSTHH 1539
Cdd:PRK13540   160 ELSLLTIITKIQEHRakggAVLLTSHQ 186
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
2286-2435 2.15e-11

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 66.66  E-value: 2.15e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2286 GECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgslghvdshsslVGYCPQEDALDDLVTVEEHLYFYARVHGIP 2365
Cdd:cd03237     25 SEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDT------------VSYKPQYIKADYEGTVRDLLSSITKDFYTH 92
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2366 EKDIKEtvhkLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKII 2435
Cdd:cd03237     93 PYFKTE----IAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVI 158
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
2191-2450 2.60e-11

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 69.04  E-value: 2.60e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2191 AMFVALVSQgtMFFSLRLLINE-SLIKKLRLFFRKfnsshVRETIDEDEDVR----AERLRVESGAAEFDLVqlyclTKT 2265
Cdd:COG1132    281 VAFILYLLR--LFGPLRQLANVlNQLQRALASAER-----IFELLDEPPEIPdppgAVPLPPVRGEIEFENV-----SFS 348
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2266 YQlihKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrnktgslGHVD----SHSSL---VGY 2338
Cdd:COG1132    349 YP---GDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILI-------DGVDirdlTLESLrrqIGV 418
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2339 CPQEDAL-DDlvTVEEHLyFYARvHGIPEKDIKETvhklLRRLHLMPF------------KDRATSMcSYGTKRKLSTAL 2405
Cdd:COG1132    419 VPQDTFLfSG--TIRENI-RYGR-PDATDEEVEEA----AKAAQAHEFiealpdgydtvvGERGVNL-SGGQRQRIAIAR 489
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 2462571778 2406 ALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKcSVILTSH 2450
Cdd:COG1132    490 ALLKDPPILILDEATSALDTETEALIQEALERLMKGR-TTIVIAH 533
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
2276-2474 2.61e-11

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 68.33  E-value: 2.61e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDDLVTVEE-- 2353
Cdd:PRK09536    19 LDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRVASVPQDTSLSFEFDVRQvv 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 ------HLyfyARVHGIPEKDiKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKS 2427
Cdd:PRK09536    99 emgrtpHR---SRFDTWTETD-RAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDINH 174
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2462571778 2428 KRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIG 2474
Cdd:PRK09536   175 QVRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAG 221
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
1351-1557 2.62e-11

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 63.62  E-value: 2.62e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVyGKDIKtdlhtvrknmgvcmqhd 1430
Cdd:cd03221      3 LENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTW-GSTVK----------------- 64
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 vlFSYLTtkehlllygsikvphwtkkQlheevkrtlkdtglyshrhkrvgtLSGGMKRKLSISIALIGGSRVVILDEPST 1510
Cdd:cd03221     65 --IGYFE-------------------Q------------------------LSGGEKMRLALAKLLLENPNLLLLDEPTN 99
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1511 GVDPCSRRSIWDVIskNKTARTIILSTH---HLDEaevLSDRIAFLEQGG 1557
Cdd:cd03221    100 HLDLESIEALEEAL--KEYPGTVILVSHdryFLDQ---VATKIIELEDGK 144
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
1364-1570 2.73e-11

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 68.88  E-value: 2.73e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1364 VDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDL------------------------HTV 1419
Cdd:PRK10762   268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSpqdglangivyisedrkrdglvlgMSV 347
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1420 RKNMGVC-MQHdvlFSYLttkehlllYGSIKvphwtkkqlHEEVKRTLKD-TGLYS----HRHKRVGTLSGGMKRKLSIS 1493
Cdd:PRK10762   348 KENMSLTaLRY---FSRA--------GGSLK---------HADEQQAVSDfIRLFNiktpSMEQAIGLLSGGNQQKVAIA 407
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1494 IALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKT-ARTIILSTHHLDEAEVLSDRIAFLEQGglRCCGSpFYLKEA 1570
Cdd:PRK10762   408 RGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAeGLSIILVSSEMPEVLGMSDRILVMHEG--RISGE-FTREQA 482
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
2263-2468 2.85e-11

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 66.34  E-value: 2.85e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2263 TKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLT--GDIIPssgNILIrnkTGSLGHvDSHSSlvgYCP 2340
Cdd:PRK14239     8 VSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINrmNDLNP---EVTI---TGSIVY-NGHNI---YSP 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2341 QEDALD-----DLV---------TVEEHLYFYARVHGIPEKDI-KETVHKLLR----------RLHlmpfkDRATSMcSY 2395
Cdd:PRK14239    78 RTDTVDlrkeiGMVfqqpnpfpmSIYENVVYGLRLKGIKDKQVlDEAVEKSLKgasiwdevkdRLH-----DSALGL-SG 151
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 2396 GTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISeEVQNKCSVILTSHSMEECEALCTRLAIMVNG 2468
Cdd:PRK14239   152 GQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLL-GLKDDYTMLLVTRSMQQASRISDRTGFFLDG 223
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
1354-1558 3.13e-11

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 65.67  E-value: 3.13e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1354 VTKIY-GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI----KTDLHTVRKNMGVCMQ 1428
Cdd:PRK10908     7 VSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDItrlkNREVPFLRRQIGMIFQ 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 hdvlfsylttKEHLLL----YGSIKVPHWTKKQLHEEVKR----TLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGS 1500
Cdd:PRK10908    87 ----------DHHLLMdrtvYDNVAIPLIIAGASGDDIRRrvsaALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKP 156
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1501 RVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGL 1558
Cdd:PRK10908   157 AVLLADEPTGNLDDALSEGILRLFEEfNRVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
2275-2446 4.02e-11

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 65.33  E-value: 4.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRnktgslGH------VDSHSSLVGYCPQEDAL-DD 2347
Cdd:cd03251     17 VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILID------GHdvrdytLASLRRQIGLVSQDVFLfND 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2348 lvTVEEHLYfYARvHGIPEKDIKETvhklLRRLHLMPF------------KDRATSMcSYGTKRKLSTALALIGKPSILL 2415
Cdd:cd03251     91 --TVAENIA-YGR-PGATREEVEEA----ARAANAHEFimelpegydtviGERGVKL-SGGQRQRIAIARALLKDPPILI 161
                          170       180       190
                   ....*....|....*....|....*....|.
gi 2462571778 2416 LDEPSSGMDPKSKRHLWKIISEEVQNKCSVI 2446
Cdd:cd03251    162 LDEATSALDTESERLVQAALERLMKNRTTFV 192
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
2275-2469 4.49e-11

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 64.86  E-value: 4.49e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK--TGSLGHVDSHSSLVGYCPQEDALDDLVTVE 2352
Cdd:cd03262     15 VLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLklTDDKKNINELRQKVGMVFQQFNLFPHLTVL 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2353 EHLYFYAR-VHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHL 2431
Cdd:cd03262     95 ENITLAPIkVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVGEV 174
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 2462571778 2432 WKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:cd03262    175 LDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGR 212
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
1351-1538 4.81e-11

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 68.21  E-value: 4.81e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYGS---KVAV-DNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT----DLHTVRK- 1421
Cdd:PRK10535     7 LKDIRRSYPSgeeQVEVlKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATldadALAQLRRe 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1422 NMGVCMQHDVLFSYLTTKEhlllygSIKVPH----WTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALI 1497
Cdd:PRK10535    87 HFGFIFQRYHLLSHLTAAQ------NVEVPAvyagLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALM 160
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 2462571778 1498 GGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTH 1538
Cdd:PRK10535   161 NGGQVILADEPTGALDSHSGEEVMAILHQlRDRGHTVIIVTH 202
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
1359-1557 5.13e-11

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 65.12  E-value: 5.13e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1359 GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSYlt 1437
Cdd:PRK10247    18 GDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTlKPEIYRQQVSYCAQTPTLFGD-- 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1438 tkehlLLYGSIKVPhWTKKQLHEEVKRTLKDT---GLYSHR-HKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVD 1513
Cdd:PRK10247    96 -----TVYDNLIFP-WQIRNQQPDPAIFLDDLerfALPDTIlTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALD 169
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462571778 1514 PCSRRSIWDVISKNKTARTI--ILSTHHLDEAEVLSDRIAFLEQGG 1557
Cdd:PRK10247   170 ESNKHNVNEIIHRYVREQNIavLWVTHDKDEINHADKVITLQPHAG 215
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
1364-1559 6.34e-11

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 67.65  E-value: 6.34e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1364 VDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLF-GASAGTIFVYGK--DIKTDLHTVRKnmGVCM-----QHDVLFSY 1435
Cdd:PRK13549   278 VDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYpGRWEGEIFIDGKpvKIRNPQQAIAQ--GIAMvpedrKRDGIVPV 355
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 LTTKEHLLLYGSIKVPHWTK-------KQLHEEVKRTLKDTglySHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP 1508
Cdd:PRK13549   356 MGVGKNITLAALDRFTGGSRiddaaelKTILESIQRLKVKT---ASPELAIARLSGGNQQKAVLAKCLLLNPKILILDEP 432
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1509 STGVDPCSRRSIWDVIskNKTAR---TIILSTHHLDEAEVLSDRIAFLEQGGLR 1559
Cdd:PRK13549   433 TRGIDVGAKYEIYKLI--NQLVQqgvAIIVISSELPEVLGLSDRVLVMHEGKLK 484
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
1364-1559 6.49e-11

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 67.54  E-value: 6.49e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1364 VDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLF-GASAGTIFVYGK--DIKTDLHTVRKnmGVCM-----QHDVLFSY 1435
Cdd:TIGR02633  276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYpGKFEGNVFINGKpvDIRNPAQAIRA--GIAMvpedrKRHGIVPI 353
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 LTTKEHLLLygSIKVPHWTKKQLHEEVKRTLKDTGLY------SHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPS 1509
Cdd:TIGR02633  354 LGVGKNITL--SVLKSFCFKMRIDAAAELQIIGSAIQrlkvktASPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPT 431
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1510 TGVDPCSRRSIWDVIskNKTAR---TIILSTHHLDEAEVLSDRIAFLEQGGLR 1559
Cdd:TIGR02633  432 RGVDVGAKYEIYKLI--NQLAQegvAIIVVSSELAEVLGLSDRVLVIGEGKLK 482
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
2275-2485 7.67e-11

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 64.81  E-value: 7.67e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgSLGHVDSHS--SLVGYCPQEDAL------D 2346
Cdd:cd03252     17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGH--DLALADPAWlrRQVGVVLQENVLfnrsirD 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2347 DLVTVEEhlyfyarvhGIPEKDIKET-----VHKLLRRLHL---MPFKDRATSMcSYGTKRKLSTALALIGKPSILLLDE 2418
Cdd:cd03252     95 NIALADP---------GMSMERVIEAaklagAHDFISELPEgydTIVGEQGAGL-SGGQRQRIAIARALIHNPRILIFDE 164
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2419 PSSGMDPKSKRhlwkIISEEVQNKC---SVILTSHSMEECEAlCTRLAIMVNGKFQCIGSLQHIKSRFGR 2485
Cdd:cd03252    165 ATSALDYESEH----AIMRNMHDICagrTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLAENGL 229
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
2269-2468 8.68e-11

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 67.00  E-value: 8.68e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2269 IHKKIIAVN---NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRnktgslGHVDSHSS----------L 2335
Cdd:PRK15439    17 ISKQYSGVEvlkGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIG------GNPCARLTpakahqlgiyL 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2336 VgycPQEDALDDLVTVEEHLYFyarvhGIPEK-DIKETVHKLLRRL--HLMPfkDRATSMCSYGTKRKLSTALALIGKPS 2412
Cdd:PRK15439    91 V---PQEPLLFPNLSVKENILF-----GLPKRqASMQKMKQLLAALgcQLDL--DSSAGSLEVADRQIVEILRGLMRDSR 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 2413 ILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNG 2468
Cdd:PRK15439   161 ILILDEPTASLTPAETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDG 216
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
2276-2450 8.96e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 63.82  E-value: 8.96e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI--RNKTGSLGHVDSHSSLVGYcpqEDALDDLVTVEE 2353
Cdd:PRK13540    17 LQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFerQSIKKDLCTYQKQLCFVGH---RSGINPYLTLRE 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 HLYFyarvhGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWK 2433
Cdd:PRK13540    94 NCLY-----DIHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIIT 168
                          170
                   ....*....|....*..
gi 2462571778 2434 IISEEVQNKCSVILTSH 2450
Cdd:PRK13540   169 KIQEHRAKGGAVLLTSH 185
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
2279-2424 9.08e-11

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 65.19  E-value: 9.08e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2279 ISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDDLVTVEEhLYFY 2358
Cdd:PRK10575    30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPAAEGMTVRE-LVAI 108
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2359 ARV--HG----IPEKDiKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:PRK10575   109 GRYpwHGalgrFGAAD-REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD 179
PLN03211 PLN03211
ABC transporter G-25; Provisional
1374-1539 1.24e-10

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 67.21  E-value: 1.24e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1374 GHITSLLGPNGAGKTTTISMLTGLFGAS--AGTIFVYGKDIKTDlhtVRKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVP 1451
Cdd:PLN03211    94 GEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPTKQ---ILKRTGFVTQDDILYPHLTVRETLVFCSLLRLP 170
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1452 HWTKKQLHEEVKRT-LKDTGLYSHRHKRVGT-----LSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSR-RSIWDVI 1524
Cdd:PLN03211   171 KSLTKQEKILVAESvISELGLTKCENTIIGNsfirgISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAyRLVLTLG 250
                          170
                   ....*....|....*
gi 2462571778 1525 SKNKTARTIILSTHH 1539
Cdd:PLN03211   251 SLAQKGKTIVTSMHQ 265
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
1353-1556 1.32e-10

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 66.68  E-value: 1.32e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIktDLHTVRKNM--GVCMQHD 1430
Cdd:PRK10982     3 NISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEI--DFKSSKEALenGISMVHQ 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSYL--TTKEHLLL--YgSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILD 1506
Cdd:PRK10982    81 ELNLVLqrSVMDNMWLgrY-PTKGMFVDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMD 159
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1507 EPSTGVDPCSRRSIWDVISKNKTART-IILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK10982   160 EPTSSLTEKEVNHLFTIIRKLKERGCgIVYISHKMEEIFQLCDEITILRDG 210
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
2275-2469 1.42e-10

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 65.11  E-value: 1.42e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNI--LIRNKtgslgHVDSHSSLVgycpqEDALDDLV--- 2349
Cdd:PRK13651    22 ALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewIFKDE-----KNKKKTKEK-----EKVLEKLViqk 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2350 ------------------------------TVEEHLYFYARVHGIPEKDIKETVHKLLRRLHL-MPFKDRATSMCSYGTK 2398
Cdd:PRK13651    92 trfkkikkikeirrrvgvvfqfaeyqlfeqTIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLdESYLQRSPFELSGGQK 171
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 2399 RKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK13651   172 RRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEWTKRTIFFKDGK 242
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
1349-1564 1.64e-10

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 63.98  E-value: 1.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIfvygkdiktdLHTVRKNMGVCMQ 1428
Cdd:PRK09544     5 VSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI----------KRNGKLRIGYVPQ 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSY--LTTKEHLLLYGSIKvphwtKKQLHEEVKRTLKDTGLYSHRHKrvgtLSGGMKRKLSISIALIGGSRVVILD 1506
Cdd:PRK09544    75 KLYLDTTlpLTVNRFLRLRPGTK-----KEDILPALKRVQAGHLIDAPMQK----LSGGETQRVLLARALLNRPQLLVLD 145
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1507 EPSTGVDPCSRRSIWDVIS--KNKTARTIILSTHHLDEAEVLSDRIAFLEQgGLRCCGSP 1564
Cdd:PRK09544   146 EPTQGVDVNGQVALYDLIDqlRRELDCAVLMVSHDLHLVMAKTDEVLCLNH-HICCSGTP 204
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
1370-1564 1.64e-10

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 63.97  E-value: 1.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1370 NFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGtifvygkDIKTDLHTVRKNmgvcmQHDVLFSYLTTKEHLLLygSIK 1449
Cdd:cd03237     21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEG-------DIEIELDTVSYK-----PQYIKADYEGTVRDLLS--SIT 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1450 VPHWTKKQLHEEVKRTLKDTGLYShrhKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVI----- 1524
Cdd:cd03237     87 KDFYTHPYFKTEIAKPLQIEQILD---REVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIrrfae 163
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 2462571778 1525 SKNKTARTIilsTHHLDEAEVLSDR-IAFLEQGGLRCCGSP 1564
Cdd:cd03237    164 NNEKTAFVV---EHDIIMIDYLADRlIVFEGEPSVNGVANP 201
cbiO PRK13645
energy-coupling factor transporter ATPase;
2275-2528 1.70e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 64.64  E-value: 1.70e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRN--------KTGSLGHVDSHSSLVGYCPQEDALD 2346
Cdd:PRK13645    26 ALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDyaipanlkKIKEVKRLRKEIGLVFQFPEYQLFQ 105
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2347 DlvTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHL-MPFKDRATSMCSYGTKRKLSTA--LALIGKpsILLLDEPSSGM 2423
Cdd:PRK13645   106 E--TIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAgiIAMDGN--TLVLDEPTGGL 181
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2424 DPKSKRHLWKIISEEVQN-KCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHIKSrfgrgftvkvhlknnkvTMET 2502
Cdd:PRK13645   182 DPKGEEDFINLFERLNKEyKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFS-----------------NQEL 244
                          250       260       270
                   ....*....|....*....|....*....|.
gi 2462571778 2503 LTKfMQLHFPKTY-----LKDQHLSMLEYHV 2528
Cdd:PRK13645   245 LTK-IEIDPPKLYqlmykLKNKGIDLLNKNI 274
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
2272-2454 2.01e-10

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 64.03  E-value: 2.01e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2272 KIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKML--TGDIIPS---SGNILIRNKTGSLGHVD-----SHSSLVGYCPQ 2341
Cdd:PRK14243    22 SFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFnrLNDLIPGfrvEGKVTFHGKNLYAPDVDpvevrRRIGMVFQKPN 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDAlddlVTVEEHLYFYARVHGIpEKDIKETVHKLLRRLHLM-----PFKDRATSMcSYGTKRKLSTALALIGKPSILLL 2416
Cdd:PRK14243   102 PFP----KSIYDNIAYGARINGY-KGDMDELVERSLRQAALWdevkdKLKQSGLSL-SGGQQQRLCIARAIAVQPEVILM 175
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 2462571778 2417 DEPSSGMDPKSKRHLWKIISEEVQNKCSVILTsHSMEE 2454
Cdd:PRK14243   176 DEPCSALDPISTLRIEELMHELKEQYTIIIVT-HNMQQ 212
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
1352-1556 2.55e-10

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 63.67  E-value: 2.55e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1352 HGVTKIY---------GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI----KTDLHT 1418
Cdd:TIGR02769    6 RDVTHTYrtgglfgakQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLyqldRKQRRA 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1419 VRKNMGVCMQHdvlfSYLTTKEHLLLYGSIKVP--HWTKKQLHEEVKRT---LKDTGLYS-HRHKRVGTLSGGMKRKLSI 1492
Cdd:TIGR02769   86 FRRDVQLVFQD----SPSAVNPRMTVRQIIGEPlrHLTSLDESEQKARIaelLDMVGLRSeDADKLPRQLSGGQLQRINI 161
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 1493 SIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTI--ILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:TIGR02769  162 ARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTayLFITHDLRLVQSFCQRVAVMDKG 227
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
1359-1557 3.26e-10

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 61.88  E-value: 3.26e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1359 GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTG--LFGASAGTIFVYGKDIKTDLhtvRKNMGVCMQHDVLFSYL 1436
Cdd:cd03232     18 GKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGrkTAGVITGEILINGRPLDKNF---QRSTGYVEQQDVHSPNL 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1437 TTKEHLLLYGSIKvphwtkkqlheevkrtlkdtglyshrhkrvgTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPcs 1516
Cdd:cd03232     95 TVREALRFSALLR-------------------------------GLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDS-- 141
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462571778 1517 rRSIWDVISK-NKTART--IILSTHHLDEAEVLS--DRIAFLEQGG 1557
Cdd:cd03232    142 -QAAYNIVRFlKKLADSgqAILCTIHQPSASIFEkfDRLLLLKRGG 186
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
1360-1556 3.27e-10

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 62.10  E-value: 3.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1360 SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKdiktdlhtvrknMGVCMQHDVLFSyLTTK 1439
Cdd:cd03250     17 TSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS------------IAYVSQEPWIQN-GTIR 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1440 EHLLlygsikvphWTKKQLHEEVKRTLKDTGLyshrhKR------------VG----TLSGGMKRKLSISIALIGGSRVV 1503
Cdd:cd03250     84 ENIL---------FGKPFDEERYEKVIKACAL-----EPdleilpdgdlteIGekgiNLSGGQKQRISLARAVYSDADIY 149
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1504 ILDEPSTGVDPCSRRSIWD-VISKN-KTARTIILSTHHLdeaEVLS--DRIAFLEQG 1556
Cdd:cd03250    150 LLDDPLSAVDAHVGRHIFEnCILGLlLNNKTRILVTHQL---QLLPhaDQIVVLDNG 203
PLN03140 PLN03140
ABC transporter G family member; Provisional
2291-2450 6.07e-10

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 65.25  E-value: 6.07e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2291 LLGVNGAGKTTIFKML----TGDIIpsSGNILIrnkTGSLGHVDSHSSLVGYCPQEDALDDLVTVEEHLYFYARVHgIPE 2366
Cdd:PLN03140   911 LMGVSGAGKTTLMDVLagrkTGGYI--EGDIRI---SGFPKKQETFARISGYCEQNDIHSPQVTVRESLIYSAFLR-LPK 984
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2367 KDIKET----VHKLLRRLHLMPFKDRATSM-----CSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISE 2437
Cdd:PLN03140   985 EVSKEEkmmfVDEVMELVELDNLKDAIVGLpgvtgLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRN 1064
                          170
                   ....*....|...
gi 2462571778 2438 EVQNKCSVILTSH 2450
Cdd:PLN03140  1065 TVDTGRTVVCTIH 1077
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
2275-2505 6.12e-10

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 64.44  E-value: 6.12e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTG--DIIPSSGNILIR-NKTGSLGHVDSHSSLVGYCP-------QEDA 2344
Cdd:TIGR03269   15 VLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGmdQYEPTSGRIIYHvALCEKCGYVERPSKVGEPCPvcggtlePEEV 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2345 ----LDDLVTVEEH------------LYFYARV-----HGIPEKDI--KETVHKLLRRLHLMPFKDRATSMC---SYGTK 2398
Cdd:TIGR03269   95 dfwnLSDKLRRRIRkriaimlqrtfaLYGDDTVldnvlEALEEIGYegKEAVGRAVDLIEMVQLSHRITHIArdlSGGEK 174
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2399 RKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNK-CSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQ 2477
Cdd:TIGR03269  175 QRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASgISMVLTSHWPEVIEDLSDKAIWLENGEIKEEGTPD 254
                          250       260       270
                   ....*....|....*....|....*....|...
gi 2462571778 2478 HIKSRFGRGFTV-----KVHLKNNKVTMETLTK 2505
Cdd:TIGR03269  255 EVVAVFMEGVSEvekecEVEVGEPIIKVRNVSK 287
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
1352-1513 6.81e-10

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 64.57  E-value: 6.81e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1352 HGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIfVYGKdiktdlhTVRknMG-VCMQHD 1430
Cdd:TIGR03719  326 ENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTI-EIGE-------TVK--LAyVDQSRD 395
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSYLTTKEH------LLLYGSIKVPhwtkkqlheevkrtlkdTGLYSHR--------HKRVGTLSGGMKRKLSISIAL 1496
Cdd:TIGR03719  396 ALDPNKTVWEEisggldIIKLGKREIP-----------------SRAYVGRfnfkgsdqQKKVGQLSGGERNRVHLAKTL 458
                          170
                   ....*....|....*..
gi 2462571778 1497 IGGSRVVILDEPSTGVD 1513
Cdd:TIGR03719  459 KSGGNVLLLDEPTNDLD 475
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
2243-2470 7.45e-10

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 62.42  E-value: 7.45e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2243 ERLRVESGAAEFDLVQLYCLTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLT--GDIIPS---SGNI 2317
Cdd:PRK14271     4 ERLGGQSGAADVDAAAPAMAAVNLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNrmNDKVSGyrySGDV 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2318 LIRNKT-GSLGHVDSHSSLVGYCPQEDALDDLvTVEEHLYFYARVHG-IPEKDIKETVHKLLRRLHLM-PFKDRATS--- 2391
Cdd:PRK14271    84 LLGGRSiFNYRDVLEFRRRVGMLFQRPNPFPM-SIMDNVLAGVRAHKlVPRKEFRGVAQARLTEVGLWdAVKDRLSDspf 162
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 2392 MCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIIsEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKF 2470
Cdd:PRK14271   163 RLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFI-RSLADRLTVIIVTHNLAQAARISDRAALFFDGRL 240
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
2262-2469 8.04e-10

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 62.00  E-value: 8.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQliHKKIIavNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILirnktgslghvdshsslVGYCPQ 2341
Cdd:PRK11247    18 VSKRYG--ERTVL--NQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELL-----------------AGTAPL 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLvtveeHLYFY-ARVhgIPEKDIKETV---------HKLLRRLHLMPFKDRAT---SMCSYGTKRKLSTALALI 2408
Cdd:PRK11247    77 AEAREDT-----RLMFQdARL--LPWKKVIDNVglglkgqwrDAALQALAAVGLADRANewpAALSGGQKQRVALARALI 149
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2409 GKPSILLLDEPSSGMDPKSK-------RHLWKiiseevQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK11247   150 HRPGLLLLDEPLGALDALTRiemqdliESLWQ------QHGFTVLLVTHDVSEAVAMADRVLLIEEGK 211
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
1363-1513 8.13e-10

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 63.19  E-value: 8.13e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI----KTDLHTVRKNMGVCMQhDVLFSY--- 1435
Cdd:PRK15079    36 AVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLlgmkDDEWRAVRSDIQMIFQ-DPLASLnpr 114
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 LTT----KEHLLLYgsikVPHWTKKQLHEEVKRTLKDTGL-------YSHRhkrvgtLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:PRK15079   115 MTIgeiiAEPLRTY----HPKLSRQEVKDRVKAMMLKVGLlpnlinrYPHE------FSGGQCQRIGIARALILEPKLII 184

                   ....*....
gi 2462571778 1505 LDEPSTGVD 1513
Cdd:PRK15079   185 CDEPVSALD 193
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
2273-2427 8.63e-10

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 61.40  E-value: 8.63e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2273 IIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDDlVTVE 2352
Cdd:cd03249     16 VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWLRSQIGLVSQEPVLFD-GTIA 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2353 EHLYFyarvhGIPEKDIKETV--------HKLLRRLhlmPFK------DRATSMcSYGTKRKLSTALALIGKPSILLLDE 2418
Cdd:cd03249     95 ENIRY-----GKPDATDEEVEeaakkaniHDFIMSL---PDGydtlvgERGSQL-SGGQKQRIAIARALLRNPKILLLDE 165

                   ....*....
gi 2462571778 2419 PSSGMDPKS 2427
Cdd:cd03249    166 ATSALDAES 174
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
2256-2424 1.05e-09

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 61.73  E-value: 1.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2256 LVQLYCLTKTYQ----LIHKKII-AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVD 2330
Cdd:PRK15112     4 LLEVRNLSKTFRyrtgWFRRQTVeAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYS 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2331 SHSSLVGYCPQEDA------------LDDLVTVEEHLYFYARvhgipEKDIKETvhklLRRLHLMPfkDRAT---SMCSY 2395
Cdd:PRK15112    84 YRSQRIRMIFQDPStslnprqrisqiLDFPLRLNTDLEPEQR-----EKQIIET----LRQVGLLP--DHASyypHMLAP 152
                          170       180
                   ....*....|....*....|....*....
gi 2462571778 2396 GTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:PRK15112   153 GQKQRLGLARALILRPKVIIADEALASLD 181
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
1325-1557 1.24e-09

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 64.36  E-value: 1.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1325 ASKTSPEYMFSSNIEPEP-------KDLTVGVALHGvtkiyGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISML--- 1394
Cdd:TIGR00956  738 LTDESDDVNDEKDMEKESgedifhwRNLTYEVKIKK-----EKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLaer 812
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1395 --TGLFgaSAGTIFVYGKDIKTdlhTVRKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVP-HWTKKQLHEEVKRTLKDTGL 1471
Cdd:TIGR00956  813 vtTGVI--TGGDRLVNGRPLDS---SFQRSIGYVQQQDLHLPTSTVRESLRFSAYLRQPkSVSKSEKMEYVEEVIKLLEM 887
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1472 YSHRHKRVGTLSGGM----KRKLSISIALIGGSRVVI-LDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVL 1546
Cdd:TIGR00956  888 ESYADAVVGVPGEGLnveqRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSAILF 967
                          250
                   ....*....|...
gi 2462571778 1547 S--DRIAFLEQGG 1557
Cdd:TIGR00956  968 EefDRLLLLQKGG 980
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
2262-2435 1.45e-09

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 63.97  E-value: 1.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKML----TGDIIpSSGNILIrnktGSLGHVDSHSSLVG 2337
Cdd:TIGR00956  765 LTYEVKIKKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLaervTTGVI-TGGDRLV----NGRPLDSSFQRSIG 839
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2338 YCPQEDALDDLVTVEEHLYFYARVH---GIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYG----TKRKLSTALALIGK 2410
Cdd:TIGR00956  840 YVQQQDLHLPTSTVRESLRFSAYLRqpkSVSKSEKMEYVEEVIKLLEMESYADAVVGVPGEGlnveQRKRLTIGVELVAK 919
                          170       180
                   ....*....|....*....|....*.
gi 2462571778 2411 PSILL-LDEPSSGMDPKSKrhlWKII 2435
Cdd:TIGR00956  920 PKLLLfLDEPTSGLDSQTA---WSIC 942
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
1360-1558 1.46e-09

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 63.58  E-value: 1.46e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1360 SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSYlTT 1438
Cdd:PRK10789   327 DHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKlQLDSWRSRLAVVSQTPFLFSD-TV 405
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1439 KEHLLLyGSikvPHWTKKQL---------HEEVKRTLKdtGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPS 1509
Cdd:PRK10789   406 ANNIAL-GR---PDATQQEIehvarlasvHDDILRLPQ--GYDTEVGERGVMLSGGQKQRISIARALLLNAEILILDDAL 479
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 1510 TGVDPCSRRSIWDVISKNKTARTIILSTHHLdEAEVLSDRIAFLEQGGL 1558
Cdd:PRK10789   480 SAVDGRTEHQILHNLRQWGEGRTVIISAHRL-SALTEASEILVMQHGHI 527
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
2262-2469 1.46e-09

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 60.75  E-value: 1.46e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLIHKKIiavnniSIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgslgHVDSHSSL--VGYC 2339
Cdd:PRK10771     7 ITWLYHHLPMRF------DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQD----HTTTPPSRrpVSML 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2340 PQEDALDDLVTVEEHLYFyarvhGI-P----EKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSIL 2414
Cdd:PRK10771    77 FQENNLFSHLTVAQNIGL-----GLnPglklNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPIL 151
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 2415 LLDEPSSGMDPKSKRHLWKIISEEVQNK-CSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK10771   152 LLDEPFSALDPALRQEMLTLVSQVCQERqLTLLMVSHSLEDAARIAPRSLVVADGR 207
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
1364-1558 1.51e-09

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 63.26  E-value: 1.51e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1364 VDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI--KTDLHTVRKNMGVCMQH---DVLFSYLTT 1438
Cdd:PRK09700   279 VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDIspRSPLDAVKKGMAYITESrrdNGFFPNFSI 358
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1439 KEHLLLYGSIKVPHW----------TKKQLHEEVKrtlKDTGLYSHR-HKRVGTLSGGMKRKLSISIALIGGSRVVILDE 1507
Cdd:PRK09700   359 AQNMAISRSLKDGGYkgamglfhevDEQRTAENQR---ELLALKCHSvNQNITELSGGNQQKVLISKWLCCCPEVIIFDE 435
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1508 PSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGL 1558
Cdd:PRK09700   436 PTRGIDVGAKAEIYKVMRQlADDGKVILMVSSELPEIITVCDRIAVFCEGRL 487
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
2266-2471 1.57e-09

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 63.31  E-value: 1.57e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2266 YQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGdIIPS--SGNILIRNKTGSLGH-VDSHSSLVGYCPQE 2342
Cdd:TIGR02633  266 WDVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFG-AYPGkfEGNVFINGKPVDIRNpAQAIRAGIAMVPED 344
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2343 DALDDLV-----------TVEEHLYFYARVHGIPEKDIketVHKLLRRLHLMPFK-DRATSMCSYGTKRKLSTALALIGK 2410
Cdd:TIGR02633  345 RKRHGIVpilgvgknitlSVLKSFCFKMRIDAAAELQI---IGSAIQRLKVKTASpFLPIGRLSGGNQQKAVLAKMLLTN 421
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 2411 PSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQ 2471
Cdd:TIGR02633  422 PRVLILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKLK 482
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
2277-2461 1.90e-09

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 62.99  E-value: 1.90e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2277 NNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIlirnKTgslghvdSHSSLVGYCPQ--EDALDDLVTVEEH 2354
Cdd:PRK15064   336 KNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV----KW-------SENANIGYYAQdhAYDFENDLTLFDW 404
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 LYFYARvhgipEKDIKETVHKLLRRLhLMPFKD--RATSMCSYGTK-RKLSTALALiGKPSILLLDEPSSGMDPKSkrhl 2431
Cdd:PRK15064   405 MSQWRQ-----EGDDEQAVRGTLGRL-LFSQDDikKSVKVLSGGEKgRMLFGKLMM-QKPNVLVMDEPTNHMDMES---- 473
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2462571778 2432 wkIisEEVQN-----KCSVILTSHSMEECEALCTR 2461
Cdd:PRK15064   474 --I--ESLNMalekyEGTLIFVSHDREFVSSLATR 504
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
1338-1558 1.96e-09

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 62.94  E-value: 1.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1338 IEPEPKDLTVgVALHGvtkiygsKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGlFGASAGTIFVYGKDIKT-DL 1416
Cdd:PRK11174   348 VTIEAEDLEI-LSPDG-------KTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLG-FLPYQGSLKINGIELRElDP 418
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1417 HTVRKNMGVCMQHDVLFsYLTTKEHLLLyGSikvPHWTKKQLHEEVKRT-------LKDTGLYSHRHKRVGTLSGGMKRK 1489
Cdd:PRK11174   419 ESWRKHLSWVGQNPQLP-HGTLRDNVLL-GN---PDASDEQLQQALENAwvseflpLLPQGLDTPIGDQAAGLSVGQAQR 493
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1490 LSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLsDRIAFLEQGGL 1558
Cdd:PRK11174   494 LALARALLQPCQLLLLDEPTASLDAHSEQLVMQALNAASRRQTTLMVTHQLEDLAQW-DQIWVMQDGQI 561
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
2275-2470 2.00e-09

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 62.82  E-value: 2.00e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgslgHVDSHSSL------VGYCPQEDALDDL 2348
Cdd:PRK10982    13 ALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGK-----EIDFKSSKealengISMVHQELNLVLQ 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2349 VTVEEHLYF--YARV-----HGIPEKDIKETVHKLlrRLHLMPFKDRATsmCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:PRK10982    88 RSVMDNMWLgrYPTKgmfvdQDKMYRDTKAIFDEL--DIDIDPRAKVAT--LSVSQMQMIEIAKAFSYNAKIVIMDEPTS 163
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 2422 GMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKF 2470
Cdd:PRK10982   164 SLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQW 212
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
2276-2435 3.37e-09

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 59.20  E-value: 3.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPS---SGNILIRNKTGSLGHVDSHSSLVgYCPQEDALDDLVTVE 2352
Cdd:cd03233     23 LKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAEKYPGEII-YVSEEDVHFPTLTVR 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2353 EHLYFYARVHGipekdiketvHKLLRRLhlmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLW 2432
Cdd:cd03233    102 ETLDFALRCKG----------NEFVRGI-------------SGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTALEIL 158

                   ...
gi 2462571778 2433 KII 2435
Cdd:cd03233    159 KCI 161
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
1333-1558 3.44e-09

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 61.99  E-value: 3.44e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1333 MFSSNIEPEPKdltvgVALHGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI 1412
Cdd:PRK15439     1 MQTSDTTAPPL-----LCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPC 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1413 KTDLHTVRKNMGVCM--QHDVLFSYLTTKEHLLLygsiKVPhwtKKQLHEE-VKRTLKDTGLYSHRHKRVGTLSGGMKRK 1489
Cdd:PRK15439    76 ARLTPAKAHQLGIYLvpQEPLLFPNLSVKENILF----GLP---KRQASMQkMKQLLAALGCQLDLDSSAGSLEVADRQI 148
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1490 LSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGL 1558
Cdd:PRK15439   149 VEILRGLMRDSRILILDEPTASLTPAETERLFSRIRElLAQGVGIVFISHKLPEIRQLADRISVMRDGTI 218
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
2277-2469 3.61e-09

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 59.72  E-value: 3.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2277 NNISIGIPAGECFGLLGVNGAGKTTIFKML-------TGDII--------PSSGNILIRNKTGSlghVDSHSSLVgycPQ 2341
Cdd:PRK09493    18 HNIDLNIDQGEVVVIIGPSGSGKSTLLRCInkleeitSGDLIvdglkvndPKVDERLIRQEAGM---VFQQFYLF---PH 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLvtveehLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:PRK09493    92 LTALENV------MFGPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTS 165
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 2422 GMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK09493   166 ALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGR 213
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
1360-1572 3.63e-09

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 59.85  E-value: 3.63e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1360 SKVAVDN----LNLNFYEGHITSLLGPNGAGKTTTISMLTGLFgASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVL-- 1432
Cdd:COG4138      4 NDVAVAGrlgpISAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGRPLSDwSAAELARHRAYLSQQQSPpf 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1433 ----FSYLTtkehllLYGSIKVPHWTKKQLHEEVKRTLKDTGLYshrHKRVGTLSGGMKRK-------LSISIALIGGSR 1501
Cdd:COG4138     83 ampvFQYLA------LHQPAGASSEAVEQLLAQLAEALGLEDKL---SRPLTQLSGGEWQRvrlaavlLQVWPTINPEGQ 153
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1502 VVILDEPSTGVDPCSRRSIWDVISKNKTA-RTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGS------PFYLKEAFG 1572
Cdd:COG4138    154 LLLLDEPMNSLDVAQQAALDRLLRELCQQgITVVMSSHDLNHTLRHADRVWLLKQGKLVASGEtaevmtPENLSEVFG 231
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
2256-2471 3.65e-09

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 59.83  E-value: 3.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2256 LVQLYCLTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIR----NKTGSLGHVDS 2331
Cdd:PRK11629     5 LLQCDNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNgqpmSKLSSAAKAEL 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2332 HSSLVGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKP 2411
Cdd:PRK11629    85 RNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNP 164
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 2412 SILLLDEPSSGMDPKSKRHLWKIISE-EVQNKCSVILTSHSMEECEALCTRLAiMVNGKFQ 2471
Cdd:PRK11629   165 RLVLADEPTGNLDARNADSIFQLLGElNRLQGTAFLVVTHDLQLAKRMSRQLE-MRDGRLT 224
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
2278-2437 4.67e-09

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 59.78  E-value: 4.67e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKT------GSLGHVDSHSSLVGycpQEDALDDLVTV 2351
Cdd:PRK11831    25 NISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENipamsrSRLYTVRKRMSMLF---QSGALFTDMNV 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 EEHLYFYARVHG-IPEKDIKETV-HKL----LR-RLHLMPfkdratSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:PRK11831   102 FDNVAYPLREHTqLPAPLLHSTVmMKLeavgLRgAAKLMP------SELSGGMARRAALARAIALEPDLIMFDEPFVGQD 175
                          170
                   ....*....|...
gi 2462571778 2425 PKSKRHLWKIISE 2437
Cdd:PRK11831   176 PITMGVLVKLISE 188
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
1362-1572 4.88e-09

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 59.56  E-value: 4.88e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1362 VAVDN----LNLNFYEGHITSLLGPNGAGKTTTISMLTGLFgASAGTIFVYGKDIKT----DLHTVRKNMgvCMQHDVLF 1433
Cdd:PRK03695     6 VAVSTrlgpLSAEVRAGEILHLVGPNGAGKSTLLARMAGLL-PGSGSIQFAGQPLEAwsaaELARHRAYL--SQQQTPPF 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1434 S-----YLTtkehllLYGSIKVPHWTKKQLHEEVKRTLKDTGLYsHRHkrVGTLSGGMKRK-------LSISIALIGGSR 1501
Cdd:PRK03695    83 AmpvfqYLT------LHQPDKTRTEAVASALNEVAEALGLDDKL-GRS--VNQLSGGEWQRvrlaavvLQVWPDINPAGQ 153
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1502 VVILDEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGS------PFYLKEAFG 1572
Cdd:PRK03695   154 LLLLDEPMNSLDVAQQAALDRLLSElCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRrdevltPENLAQVFG 231
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
2275-2450 5.69e-09

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 58.66  E-value: 5.69e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTI----FKMLTgdiiPSSGNILIRNK-TGSLGHVDSHSSLvGYCPQE------- 2342
Cdd:cd03244     19 VLKNISFSIKPGEKVGIVGRTGSGKSSLllalFRLVE----LSSGSILIDGVdISKIGLHDLRSRI-SIIPQDpvlfsgt 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2343 --DALDDLvtvEEHlyfyarvhgiPEKDIKETVHK--LLRRLHLMPFKDRAT-----SMCSYGTKRKLSTALALIGKPSI 2413
Cdd:cd03244     94 irSNLDPF---GEY----------SDEELWQALERvgLKEFVESLPGGLDTVveeggENLSVGQRQLLCLARALLRKSKI 160
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2462571778 2414 LLLDEPSSGMDPKSKRHLWKIISEEVQNkCSVILTSH 2450
Cdd:cd03244    161 LVLDEATASVDPETDALIQKTIREAFKD-CTVLTIAH 196
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
2266-2454 5.71e-09

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 58.96  E-value: 5.71e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2266 YQLIHKKIiaVNNISIGIPAGEcFGLL-GVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDA 2344
Cdd:PRK10247    15 YLAGDAKI--LNNISFSLRAGE-FKLItGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQQVSYCAQTPT 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2345 L--DdlvTVEEHLYFYARVHGI-PEKDiketvhKLLRrlHLMPFK------DRATSMCSYGTKRKLSTALALIGKPSILL 2415
Cdd:PRK10247    92 LfgD---TVYDNLIFPWQIRNQqPDPA------IFLD--DLERFAlpdtilTKNIAELSGGEKQRISLIRNLQFMPKVLL 160
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2462571778 2416 LDEPSSGMDPKSKRHLWKIISEEVQNK-CSVILTSHSMEE 2454
Cdd:PRK10247   161 LDEITSALDESNKHNVNEIIHRYVREQnIAVLWVTHDKDE 200
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
1354-1556 6.50e-09

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 61.19  E-value: 6.50e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1354 VTKIYGSK--VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHD 1430
Cdd:PRK11176   347 VTFTYPGKevPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDyTLASLRNQVALVSQNV 426
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1431 VLFSylTTKEHLLLYGSikvphwTKKQLHEEVKRTLK-----------DTGLyshrHKRVG----TLSGGMKRKLSISIA 1495
Cdd:PRK11176   427 HLFN--DTIANNIAYAR------TEQYSREQIEEAARmayamdfinkmDNGL----DTVIGengvLLSGGQRQRIAIARA 494
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1496 LIGGSRVVILDEPSTGVDPCSRRSIW---DVISKNKTARTIilsTHHLDEAEVlSDRIAFLEQG 1556
Cdd:PRK11176   495 LLRDSPILILDEATSALDTESERAIQaalDELQKNRTSLVI---AHRLSTIEK-ADEILVVEDG 554
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
2275-2493 6.81e-09

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 61.38  E-value: 6.81e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgslghvdshsSLVGYCpqEDALDDLVTVEEH 2354
Cdd:PRK11160   355 VLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQ-----------PIADYS--EAALRQAISVVSQ 421
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 lyfyaRVH------------GIPEKDiKETVHKLLRRLHLMPFKDRATSM----------CSYGTKRKLSTALALIGKPS 2412
Cdd:PRK11160   422 -----RVHlfsatlrdnlllAAPNAS-DEALIEVLQQVGLEKLLEDDKGLnawlgeggrqLSGGEQRRLGIARALLHDAP 495
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2413 ILLLDEPSSGMDPKSKRHLWKIISEEVQNKcSVILTSH---SMEECEALCtrlaIMVNGKFQCIGSLQHIKSRFGRGFTV 2489
Cdd:PRK11160   496 LLLLDEPTEGLDAETERQILELLAEHAQNK-TVLMITHrltGLEQFDRIC----VMDNGQIIEQGTHQELLAQQGRYYQL 570

                   ....
gi 2462571778 2490 KVHL 2493
Cdd:PRK11160   571 KQRL 574
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
2275-2469 7.40e-09

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 60.20  E-value: 7.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTG------------------DIIPSSGniliRNKTGSLGHvdsHSSLV 2336
Cdd:PRK15093    22 AVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGvtkdnwrvtadrmrfddiDLLRLSP----RERRKLVGH---NVSMI 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2337 GYCPQEdALDDLVTVEEHLyfyarVHGIPEKDIK----ETVHKLLRR----LHLMPFKDRATSMCSY------GTKRKLS 2402
Cdd:PRK15093    95 FQEPQS-CLDPSERVGRQL-----MQNIPGWTYKgrwwQRFGWRKRRaielLHRVGIKDHKDAMRSFpyelteGECQKVM 168
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2403 TALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVI-LTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK15093   169 IAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTIlLISHDLQMLSQWADKINVLYCGQ 236
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
2283-2424 8.28e-09

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 60.98  E-value: 8.28e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2283 IPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgslghvdshsslVGYCPQEDALDDLVTVEEHLyfyarvh 2362
Cdd:PRK13409   362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELK-------------ISYKPQYIKPDYDGTVEDLL------- 421
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2363 gipeKDIKETV------HKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:PRK13409   422 ----RSITDDLgssyykSEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 485
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
2278-2476 8.79e-09

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 59.89  E-value: 8.79e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgsLghVDSHSSL--------VGYCPQEDALDDLV 2349
Cdd:PRK11144    16 TVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRV--L--FDAEKGIclppekrrIGYVFQDARLFPHY 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2350 TVEEHLYFyarvhGIPEKDiKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKR 2429
Cdd:PRK11144    92 KVRGNLRY-----GMAKSM-VAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKR 165
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2430 HLW---KIISEEVqnKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSL 2476
Cdd:PRK11144   166 ELLpylERLAREI--NIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPL 213
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
2394-2453 1.02e-08

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 59.33  E-value: 1.02e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 2394 SYGTKRKLSTALALI---GKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSME 2453
Cdd:pfam13304  238 SDGTKRLLALLAALLsalPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAQLILTTHSPL 300
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
2286-2424 1.03e-08

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 60.57  E-value: 1.03e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2286 GECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgslghvdshsslVGYCPQEDALDDLVTVEEHLYfyarvhgip 2365
Cdd:COG1245    366 GEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLK-------------ISYKPQYISPDYDGTVEEFLR--------- 423
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2366 eKDIKETV------HKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:COG1245    424 -SANTDDFgssyykTEIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 487
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
1366-1547 1.06e-08

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 58.29  E-value: 1.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1366 NLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVR-----KNMGVCMQ-HDVL--FSYLT 1437
Cdd:PRK11629    27 NVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKaelrnQKLGFIYQfHHLLpdFTALE 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1438 TKEHLLLYGSIKvphwtKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSR 1517
Cdd:PRK11629   107 NVAMPLLIGKKK-----PAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNA 181
                          170       180       190
                   ....*....|....*....|....*....|..
gi 2462571778 1518 RSIWDVISK-NKTARTIIL-STHHLDEAEVLS 1547
Cdd:PRK11629   182 DSIFQLLGElNRLQGTAFLvVTHDLQLAKRMS 213
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
1318-1557 1.28e-08

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 57.66  E-value: 1.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1318 MQNTNPSASKTSPEYMFSSNIEPEPKDLTV----GVALHGVTKiygskVAVDNLNLNFYEGHITSLLGPNGAGKTTTISM 1393
Cdd:COG2401      1 MARYNPFFVLMRVTKVYSSVLDLSERVAIVleafGVELRVVER-----YVLRDLNLEIEPGEIVLIVGASGSGKSTLLRL 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1394 LTG--LFGASAGTIFVYGKDIKTDLHTVrknmgvcmqhdvlfsylttkEHLLLYGSIKvphwtkkqlheEVKRTLKDTGL 1471
Cdd:COG2401     76 LAGalKGTPVAGCVDVPDNQFGREASLI--------------------DAIGRKGDFK-----------DAVELLNAVGL 124
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1472 ---YSHRhKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDpcsrRSIWDVISKN------KTARTIILSTHHLDE 1542
Cdd:COG2401    125 sdaVLWL-RRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLD----RQTAKRVARNlqklarRAGITLVVATHHYDV 199
                          250
                   ....*....|....*.
gi 2462571778 1543 AEVLS-DRIAFLEQGG 1557
Cdd:COG2401    200 IDDLQpDLLIFVGYGG 215
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
2286-2450 1.52e-08

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 58.15  E-value: 1.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2286 GECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIlirNKTGSLGHVDSH---SSLVGYCPQ--EDALDDLVTVEEHLYFYAR 2360
Cdd:cd03236     26 GQVLGLVGPNGIGKSTALKILAGKLKPNLGKF---DDPPDWDEILDEfrgSELQNYFTKllEGDVKVIVKPQYVDLIPKA 102
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2361 VHG-----IPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKII 2435
Cdd:cd03236    103 VKGkvgelLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRLNAARLI 182
                          170
                   ....*....|....*
gi 2462571778 2436 SEEVQNKCSVILTSH 2450
Cdd:cd03236    183 RELAEDDNYVLVVEH 197
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
1352-1556 1.94e-08

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 58.01  E-value: 1.94e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1352 HGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKD-IKTDLHT---------VRK 1421
Cdd:PRK11701    10 RGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDgQLRDLYAlseaerrrlLRT 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1422 NMGVCMQH--DVLFSYLTT----KEHLLL-----YGSI--KVPHWTKKQlheEVKRTLKDtglyshrhKRVGTLSGGMKR 1488
Cdd:PRK11701    90 EWGFVHQHprDGLRMQVSAggniGERLMAvgarhYGDIraTAGDWLERV---EIDAARID--------DLPTTFSGGMQQ 158
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1489 KLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVIsKNKTAR---TIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK11701   159 RLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLL-RGLVRElglAVVIVTHDLAVARLLAHRLLVMKQG 228
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
1378-1538 1.99e-08

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 57.48  E-value: 1.99e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1378 SLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVR-----KNMGVCMQHDVLFSYLTTKEHL----LLYGSi 1448
Cdd:PRK10584    40 ALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARaklraKHVGFVFQSFMLIPTLNALENVelpaLLRGE- 118
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1449 kvphwTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVI-SKN 1527
Cdd:PRK10584   119 -----SSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLfSLN 193
                          170
                   ....*....|..
gi 2462571778 1528 KT-ARTIILSTH 1538
Cdd:PRK10584   194 REhGTTLILVTH 205
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
2274-2424 2.28e-08

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 59.80  E-value: 2.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrNKTGSLGHVDSHSslvgycpqedaLDDLVTVEE 2353
Cdd:PRK10636   326 IILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL-AKGIKLGYFAQHQ-----------LEFLRADES 393
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2354 HLYFYARVhgIPekdiKETVHKLLRRLHLMPFK-DRATSMC---SYGTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:PRK10636   394 PLQHLARL--AP----QELEQKLRDYLGGFGFQgDKVTEETrrfSGGEKARLVLALIVWQRPNLLLLDEPTNHLD 462
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
1340-1557 3.52e-08

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 58.87  E-value: 3.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1340 PEPKDLTVGVAL----------HGVTKiYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTG-----------LF 1398
Cdd:PRK10938   243 PEPDEPSARHALpaneprivlnNGVVS-YNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGdhpqgysndltLF 321
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1399 G---ASAGTIFvygkDIKtdlhtvrKNMGvcmqhdvlfsYLTTKEHL-----------LLYG---SIKVPHWTKKQLHEE 1461
Cdd:PRK10938   322 GrrrGSGETIW----DIK-------KHIG----------YVSSSLHLdyrvstsvrnvILSGffdSIGIYQAVSDRQQKL 380
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1462 VKRTLKDTGLyshrHKRVG-----TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSR---RSIWDVISKNKTARTI 1533
Cdd:PRK10938   381 AQQWLDILGI----DKRTAdapfhSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRqlvRRFVDVLISEGETQLL 456
                          250       260
                   ....*....|....*....|....
gi 2462571778 1534 ILSTHHLDEAEVLSDRIAFLEQGG 1557
Cdd:PRK10938   457 FVSHHAEDAPACITHRLEFVPDGD 480
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
2271-2479 3.55e-08

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 57.30  E-value: 3.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2271 KKIIAvNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKtgslgHVDSHSS-----LVGYCPQEDAL 2345
Cdd:PRK10253    19 KYTVA-ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGE-----HIQHYASkevarRIGLLAQNATT 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2346 DDLVTVEEhLYFYARVHGIP-----EKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPS 2420
Cdd:PRK10253    93 PGDITVQE-LVARGRYPHQPlftrwRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPT 171
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2421 SGMDPKSKRHLWKIISEEVQNK-CSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:PRK10253   172 TWLDISHQIDLLELLSELNREKgYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
2293-2451 3.89e-08

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 56.03  E-value: 3.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2293 GVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSlghvDSHSSLVGYCPQEDALDDLVTVEEHLYFYARVHgipekDIKET 2372
Cdd:PRK13541    33 GANGCGKSSLLRMIAGIMQPSSGNIYYKNCNIN----NIAKPYCTYIGHNLGLKLEMTVFENLKFWSEIY-----NSAET 103
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 2373 VHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHS 2451
Cdd:PRK13541   104 LYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNNLIVMKANSGGIVLLSSHL 182
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
2278-2470 4.01e-08

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 58.52  E-value: 4.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKT-GSLGHVDS-HSSLVgYCPqEDALDDLVTVEEHL 2355
Cdd:PRK15439   281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEiNALSTAQRlARGLV-YLP-EDRQSSGLYLDAPL 358
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2356 YF--YARVHGIP--------EKDIKETVHKLL--RRLHLmpfkDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGM 2423
Cdd:PRK15439   359 AWnvCALTHNRRgfwikparENAVLERYRRALniKFNHA----EQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGV 434
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2462571778 2424 DPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKF 2470
Cdd:PRK15439   435 DVSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
2283-2424 4.20e-08

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 58.81  E-value: 4.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2283 IPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI--------------RNKTGS--------LGHVDSH-------S 2333
Cdd:PRK11147    26 IEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYeqdlivarlqqdppRNVEGTvydfvaegIEEQAEYlkryhdiS 105
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2334 SLVGYCPQEDALDDLVTVEEHLyfyaRVHGIPEKDIKetVHKLLRRLHLMPfkDRATSMCSYGTKRKLSTALALIGKPSI 2413
Cdd:PRK11147   106 HLVETDPSEKNLNELAKLQEQL----DHHNLWQLENR--INEVLAQLGLDP--DAALSSLSGGWLRKAALGRALVSNPDV 177
                          170
                   ....*....|.
gi 2462571778 2414 LLLDEPSSGMD 2424
Cdd:PRK11147   178 LLLDEPTNHLD 188
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
2271-2475 4.35e-08

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 55.61  E-value: 4.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2271 KKIiaVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTG--DIIPSSGNILIRNktgslghvdshsslvgycpqEDALDdl 2348
Cdd:cd03217     13 KEI--LKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGhpKYEVTEGEILFKG--------------------EDITD-- 68
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2349 VTVEEH------LYFY--ARVHGIpekdikeTVHKLLRRLHlMPFkdratsmcSYGTKRKLSTALALIGKPSILLLDEPS 2420
Cdd:cd03217     69 LPPEERarlgifLAFQypPEIPGV-------KNADFLRYVN-EGF--------SGGEKKRNEILQLLLLEPDLAILDEPD 132
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 2421 SGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEAL-CTRLAIMVNGKFQCIGS 2475
Cdd:cd03217    133 SGLDIDALRLVAEVINKLREEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGD 188
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
2279-2471 4.41e-08

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 56.90  E-value: 4.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2279 ISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNI--------LIRNKTGSLGHVDSH------SSLVGYCPQEDA 2344
Cdd:PRK10619    24 VSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIvvngqtinLVRDKDGQLKVADKNqlrllrTRLTMVFQHFNL 103
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2345 LDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMP-FKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGM 2423
Cdd:PRK10619   104 WSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDErAQGKYPVHLSGGQQQRVSIARALAMEPEVLLFDEPTSAL 183
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 2424 DPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQ 2471
Cdd:PRK10619   184 DPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIE 231
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
1363-1559 4.88e-08

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 56.75  E-value: 4.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGkdiktDLHTVRKNMGVCMQhdvlfsyLTTKEH- 1441
Cdd:PRK13546    39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG-----EVSVIAISAGLSGQ-------LTGIENi 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1442 ---LLLYGsikvphWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP-STGVDPCSR 1517
Cdd:PRK13546   107 efkMLCMG------FKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEAlSVGDQTFAQ 180
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 2462571778 1518 RSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLR 1559
Cdd:PRK13546   181 KCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLK 222
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
2250-2447 5.01e-08

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 58.49  E-value: 5.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2250 GAAEFDLVqlyclTKTYQliHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTG--DIipSSGNILIrnktgslg 2327
Cdd:PRK11176   340 GDIEFRNV-----TFTYP--GKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRfyDI--DEGEILL-------- 402
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2328 hvDSH-------SSLVGYCPqedalddLVTVEEHLY--------FYARvhgiPEKDIKETVHKLLRRLHLMPFKDRATS- 2391
Cdd:PRK11176   403 --DGHdlrdytlASLRNQVA-------LVSQNVHLFndtianniAYAR----TEQYSREQIEEAARMAYAMDFINKMDNg 469
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462571778 2392 ----------MCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVIL 2447
Cdd:PRK11176   470 ldtvigengvLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVI 535
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
2275-2475 5.25e-08

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 55.88  E-value: 5.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNK-TGSLGHVDSHSSLvGYCPQEDALDDlVTVEE 2353
Cdd:cd03369     23 VLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIdISTIPLEDLRSSL-TIIPQDPTLFS-GTIRS 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2354 HLYFYARVhgiPEKDIKETVHKLLRRLHLmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWK 2433
Cdd:cd03369    101 NLDPFDEY---SDEEIYGALRVSEGGLNL-----------SQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQK 166
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 2462571778 2434 IISEEVQNkcSVILT-SHSMEECeALCTRLAIMVNGKFQCIGS 2475
Cdd:cd03369    167 TIREEFTN--STILTiAHRLRTI-IDYDKILVMDAGEVKEYDH 206
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
2270-2469 5.38e-08

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 58.02  E-value: 5.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2270 HKKIiaVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGdIIP--SSGNILIRNKTGSLGH-VDSHSSLVGYCPQEDALD 2346
Cdd:PRK13549   274 HIKR--VDDVSFSLRRGEILGIAGLVGAGRTELVQCLFG-AYPgrWEGEIFIDGKPVKIRNpQQAIAQGIAMVPEDRKRD 350
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2347 DLVT---VEEH-----LYFYARVHGIPEKDIKETVHKLLRRLHL-MPFKDRATSMCSYGTKRKLSTALALIGKPSILLLD 2417
Cdd:PRK13549   351 GIVPvmgVGKNitlaaLDRFTGGSRIDDAAELKTILESIQRLKVkTASPELAIARLSGGNQQKAVLAKCLLLNPKILILD 430
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2418 EPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK13549   431 EPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSELPEVLGLSDRVLVMHEGK 482
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
2276-2353 6.38e-08

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 58.21  E-value: 6.38e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrNKTGSLGHVDSHsslvgycpqEDALDDLVTVEE 2353
Cdd:PRK11819   340 IDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETVKLAYVDQS---------RDALDPNKTVWE 407
PLN03073 PLN03073
ABC transporter F family; Provisional
2273-2424 6.99e-08

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 58.33  E-value: 6.99e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2273 IIAVNNISIGIPAGEC------FGL--------LGVNGAGKTTIFKMLTGDIIPSSGNIL----IRNKTGSLGHVdshss 2334
Cdd:PLN03073   508 IISFSDASFGYPGGPLlfknlnFGIdldsriamVGPNGIGKSTILKLISGELQPSSGTVFrsakVRMAVFSQHHV----- 582
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2335 lvgycpqeDALDdlVTVEEHLYFYARVHGIPEKDIketvhkllrRLHLMPF------KDRATSMCSYGTKRKLSTALALI 2408
Cdd:PLN03073   583 --------DGLD--LSSNPLLYMMRCFPGVPEQKL---------RAHLGSFgvtgnlALQPMYTLSGGQKSRVAFAKITF 643
                          170
                   ....*....|....*.
gi 2462571778 2409 GKPSILLLDEPSSGMD 2424
Cdd:PLN03073   644 KKPHILLLDEPSNHLD 659
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
1368-1513 9.54e-08

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 54.96  E-value: 9.54e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1368 NLNFY--EGHITSLLGPNGAGKTT---TISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTtkehl 1442
Cdd:cd03233     25 DFSGVvkPGEMVLVLGRPGSGCSTllkALANRTEGNVSVEGDIHYNGIPYKEFAEKYPGEIIYVSEEDVHFPTLT----- 99
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1443 llygsikvphwtkkqlheeVKRTLkDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVD 1513
Cdd:cd03233    100 -------------------VRETL-DFALRCKGNEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLD 150
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
2215-2484 1.11e-07

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 57.65  E-value: 1.11e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2215 IKKLRLFFrkfnsSHvrETIDEDEdvrAERLRVESGAAEFDLVQlyclTKTYQLIHKKIIAVNNISIGIPAGECFGLLGV 2294
Cdd:TIGR00957  607 LKRLRIFL-----SH--EELEPDS---IERRTIKPGEGNSITVH----NATFTWARDLPPTLNGITFSIPEGALVAVVGQ 672
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2295 NGAGKTTIFKMLTGDIIPSSGNILIRnktGSlghvdshsslVGYCPQEDALDDlVTVEEHLYFYarvHGIPEKDIKETVH 2374
Cdd:TIGR00957  673 VGCGKSSLLSALLAEMDKVEGHVHMK---GS----------VAYVPQQAWIQN-DSLRENILFG---KALNEKYYQQVLE 735
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2375 K--LLRRLHLMPFKDRAT-----SMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLW-KIISEE--VQNKCS 2444
Cdd:TIGR00957  736 AcaLLPDLEILPSGDRTEigekgVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFeHVIGPEgvLKNKTR 815
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2462571778 2445 VILTsHSMEECEALcTRLAIMVNGKFQCIGSLQHIKSRFG 2484
Cdd:TIGR00957  816 ILVT-HGISYLPQV-DVIIVMSGGKISEMGSYQELLQRDG 853
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
2262-2353 1.30e-07

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 56.87  E-value: 1.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQliHKKIIavNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrNKTGSLGHVDShsslvgycpQ 2341
Cdd:TIGR03719  328 LTKAFG--DKLLI--DDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETVKLAYVDQ---------S 393
                           90
                   ....*....|..
gi 2462571778 2342 EDALDDLVTVEE 2353
Cdd:TIGR03719  394 RDALDPNKTVWE 405
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
2273-2453 1.31e-07

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 54.64  E-value: 1.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2273 IIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSL----VGYCPQEDALDDl 2348
Cdd:cd03290     14 LATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRnrysVAYAAQKPWLLN- 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2349 VTVEEHLYFYARVHGIPEKDIKETVhKLLRRLHLMPFKD------RATSMcSYGTKRKLSTALALIGKPSILLLDEPSSG 2422
Cdd:cd03290     93 ATVEENITFGSPFNKQRYKAVTDAC-SLQPDIDLLPFGDqteigeRGINL-SGGQRQRICVARALYQNTNIVFLDDPFSA 170
                          170       180       190
                   ....*....|....*....|....*....|...
gi 2462571778 2423 MDPKSKRHLWK--IISEEVQNKCSVILTSHSME 2453
Cdd:cd03290    171 LDIHLSDHLMQegILKFLQDDKRTLVLVTHKLQ 203
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
1349-1556 1.38e-07

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 57.04  E-value: 1.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1349 VALHGVTKIYGS-KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNmGVCM 1427
Cdd:PRK10790   341 IDIDNVSFAYRDdNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQ-GVAM 419
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1428 -QHD--VL----FSYLTTKEHLllyGSIKVphWT---KKQLHEEVkRTLKDtGLYSHRHKRVGTLSGGMKRKLSISIALI 1497
Cdd:PRK10790   420 vQQDpvVLadtfLANVTLGRDI---SEEQV--WQaleTVQLAELA-RSLPD-GLYTPLGEQGNNLSVGQKQLLALARVLV 492
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1498 GGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAeVLSDRIAFLEQG 1556
Cdd:PRK10790   493 QTPQILILDEATANIDSGTEQAIQQALAAVREHTTLVVIAHRLSTI-VEADTILVLHRG 550
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
1351-1556 1.39e-07

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 54.75  E-value: 1.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LH--GVTKIygskVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHT--------VR 1420
Cdd:COG4778     16 LHlqGGKRL----PVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGGWVDLAQaspreilaLR 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1421 KN-MGVCMQH----------DVlfsyltTKEHLLLYGsikvphWTKKQLHEEVKRTLkdtglyshRHKRV---------G 1480
Cdd:COG4778     92 RRtIGYVSQFlrviprvsalDV------VAEPLLERG------VDREEARARARELL--------ARLNLperlwdlppA 151
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1481 TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILS-THHLDEAEVLSDRIAFLEQG 1556
Cdd:COG4778    152 TFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGiFHDEEVREAVADRVVDVTPF 228
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
2278-2463 1.92e-07

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 56.44  E-value: 1.92e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRN--KTGSLGH----------VDS----HSSLVGYCPQ 2341
Cdd:PRK15064    19 NISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPneRLGKLRQdqfafeeftvLDTvimgHTELWEVKQE 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDAL--------DDLVTVEEHLYFYARVHG---------------IPEKdiketvhkllrrLHLMPFKDRATsmcsyGTK 2398
Cdd:PRK15064    99 RDRIyalpemseEDGMKVADLEVKFAEMDGytaearagelllgvgIPEE------------QHYGLMSEVAP-----GWK 161
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 2399 RKLSTALALIGKPSILLLDEPSSGMDPKSKRHLwkiisEEVQN--KCSVILTSHSMEECEALCTRLA 2463
Cdd:PRK15064   162 LRVLLAQALFSNPDILLLDEPTNNLDINTIRWL-----EDVLNerNSTMIIISHDRHFLNSVCTHMA 223
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
1348-1563 2.51e-07

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 54.32  E-value: 2.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1348 GVALHGVTkIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGA----SAGTIFVYGKDIKtdLHTVR-KN 1422
Cdd:PRK10418     4 QIELRNIA-LQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAgvrqTAGRVLLDGKPVA--PCALRgRK 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1423 MGVCMQHD-VLFSYLTT-----KEHLLLYGSIKVPHWTKKQLH----EEVKRTLKdtgLYSHRhkrvgtLSGGMKRKLSI 1492
Cdd:PRK10418    81 IATIMQNPrSAFNPLHTmhthaRETCLALGKPADDATLTAALEavglENAARVLK---LYPFE------MSGGMLQRMMI 151
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1493 SIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGS 1563
Cdd:PRK10418   152 ALALLCEAPFIIADEPTTDLDVVAQARILDLLESivQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGD 224
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
1352-1509 2.85e-07

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 55.90  E-value: 2.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1352 HGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVyGKdiktdlhTVRknmgvcmqhdv 1431
Cdd:PRK11819   328 ENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GE-------TVK----------- 388
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1432 lFSYL-TTKEHLLlygsikvphwTKKQLHEEV----------KRTLKDTGlYSHR--------HKRVGTLSGGMKRKLSI 1492
Cdd:PRK11819   389 -LAYVdQSRDALD----------PNKTVWEEIsggldiikvgNREIPSRA-YVGRfnfkggdqQKKVGVLSGGERNRLHL 456
                          170
                   ....*....|....*..
gi 2462571778 1493 SIALIGGSRVVILDEPS 1509
Cdd:PRK11819   457 AKTLKQGGNVLLLDEPT 473
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
2274-2479 3.32e-07

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 55.87  E-value: 3.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIGIPAGECFGLLGVNGAGKTTifkmlTG----DIIPSSGNI---------LIRNKTGSLGH------VDSHSS 2334
Cdd:PRK15134   300 VVVKNISFTLRPGETLGLVGESGSGKST-----TGlallRLINSQGEIwfdgqplhnLNRRQLLPVRHriqvvfQDPNSS 374
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2335 LvgyCPQedaLDDLVTVEEHLyfyaRVH--GIPEKDIKETVHKLLRRLHLMP-FKDRATSMCSYGTKRKLSTALALIGKP 2411
Cdd:PRK15134   375 L---NPR---LNVLQIIEEGL----RVHqpTLSAAQREQQVIAVMEEVGLDPeTRHRYPAEFSGGQRQRIAIARALILKP 444
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 2412 SILLLDEPSSGMDPKSKRHLWKII-SEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIGSLQHI 2479
Cdd:PRK15134   445 SLIILDEPTSSLDKTVQAQILALLkSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERV 513
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
1351-1559 3.99e-07

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 55.36  E-value: 3.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1351 LHGVTKIYG-SKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI-KTDLHTVRKnmgvcmq 1428
Cdd:PRK10522   325 LRNVTFAYQdNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVtAEQPEDYRK------- 397
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 hdvLFSYLTTKEHL---LLYGSIKVPhwtKKQLHEEVKRTLKDTGLYSHRHKRVGT--LSGGMKRKLSISIALIGGSRVV 1503
Cdd:PRK10522   398 ---LFSAVFTDFHLfdqLLGPEGKPA---NPALVEKWLERLKMAHKLELEDGRISNlkLSKGQKKRLALLLALAEERDIL 471
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1504 ILDEPSTGVDPCSRRSIWDVI-----SKNKTARTIILSTHHLDEAevlsDRIAFLEQGGLR 1559
Cdd:PRK10522   472 LLDEWAADQDPHFRREFYQVLlpllqEMGKTIFAISHDDHYFIHA----DRLLEMRNGQLS 528
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
1356-1513 4.25e-07

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 55.48  E-value: 4.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1356 KIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFgASAGTIFVYGKDIKT----DLHTVRKNMGVCMQ--H 1429
Cdd:PRK15134   294 RTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLI-NSQGEIWFDGQPLHNlnrrQLLPVRHRIQVVFQdpN 372
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYLTTKEhlLLYGSIKV--PHWTKKQLHEEVKRTLKDTGL-YSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILD 1506
Cdd:PRK15134   373 SSLNPRLNVLQ--IIEEGLRVhqPTLSAAQREQQVIAVMEEVGLdPETRHRYPAEFSGGQRQRIAIARALILKPSLIILD 450

                   ....*..
gi 2462571778 1507 EPSTGVD 1513
Cdd:PRK15134   451 EPTSSLD 457
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
1367-1570 4.40e-07

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 54.02  E-value: 4.40e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1367 LNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSYLTTKEhLLLY 1445
Cdd:PRK10575    30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARKVAYLPQQLPAAEGMTVRE-LVAI 108
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1446 GsiKVP-HWTKKQL----HEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSI 1520
Cdd:PRK10575   109 G--RYPwHGALGRFgaadREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDV 186
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1521 WDVISKNKTAR--TIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEA 1570
Cdd:PRK10575   187 LALVHRLSQERglTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRG 238
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
2274-2469 5.02e-07

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 55.24  E-value: 5.02e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGdIIPSSGNILIRN---KTGSLGHVDSHSSLVGYCPQ--EDALDDL 2348
Cdd:PRK11174   364 TLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLG-FLPYQGSLKINGielRELDPESWRKHLSWVGQNPQlpHGTLRDN 442
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2349 VTVEEHLYFYARVHGIPEK-DIKETVHKLLRRLHLmPFKDRATSMcSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKS 2427
Cdd:PRK11174   443 VLLGNPDASDEQLQQALENaWVSEFLPLLPQGLDT-PIGDQAAGL-SVGQAQRLALARALLQPCQLLLLDEPTASLDAHS 520
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 2462571778 2428 KRHLWKIISEEVQNKCSVILTsHSMEECEAlCTRLAIMVNGK 2469
Cdd:PRK11174   521 EQLVMQALNAASRRQTTLMVT-HQLEDLAQ-WDQIWVMQDGQ 560
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
2256-2450 5.19e-07

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 55.12  E-value: 5.19e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2256 LVQLYCLTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSL 2335
Cdd:PRK10535     4 LLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQL 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2336 ----VGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKP 2411
Cdd:PRK10535    84 rrehFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGG 163
                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 2462571778 2412 SILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSH 2450
Cdd:PRK10535   164 QVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTH 202
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
2279-2469 6.08e-07

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 54.92  E-value: 6.08e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2279 ISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHV-DSHSSLVGYCPQEDALDDLV---TVEEH 2354
Cdd:PRK11288   272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPrDAIRAGIMLCPEDRKAEGIIpvhSVADN 351
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 LYFYARVHGIPEKDI------KETVHKLLRRLHL-MPFKDRATSMCSYGTKRK--LSTALALIGKpsILLLDEPSSGMDP 2425
Cdd:PRK11288   352 INISARRHHLRAGCLinnrweAENADRFIRSLNIkTPSREQLIMNLSGGNQQKaiLGRWLSEDMK--VILLDEPTRGIDV 429
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 2462571778 2426 KSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK11288   430 GAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREGR 473
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
2276-2469 6.85e-07

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 53.22  E-value: 6.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIlirnKTGSLgHVDSHSSL-------------VGYC--- 2339
Cdd:PRK11264    19 LHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTI----RVGDI-TIDTARSLsqqkglirqlrqhVGFVfqn 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2340 ----PQEDALDDLVtvEEHLYfyarVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILL 2415
Cdd:PRK11264    94 fnlfPHRTVLENII--EGPVI----VKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVIL 167
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 2416 LDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK11264   168 FDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGR 221
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
2264-2450 6.89e-07

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 52.65  E-value: 6.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2264 KTYQLIHKKIIavNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDI--IPSSGNILIRNktgslGHVDSHSSLVgycpq 2341
Cdd:COG2401     36 VELRVVERYVL--RDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVPD-----NQFGREASLI----- 103
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 eDALDDLVTVEEHLYFYARVhGIPEKdiketvhKLLRRlhlmPFKDratsmCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:COG2401    104 -DAIGRKGDFKDAVELLNAV-GLSDA-------VLWLR----RFKE-----LSTGQKFRFRLALLLAERPKLLVIDEFCS 165
                          170       180       190
                   ....*....|....*....|....*....|
gi 2462571778 2422 GMDPKSKRHLWKIISEEVQ-NKCSVILTSH 2450
Cdd:COG2401    166 HLDRQTAKRVARNLQKLARrAGITLVVATH 195
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
2276-2474 8.10e-07

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 52.92  E-value: 8.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLtgdiipssgNILIrnKTGSLGHVDSHSSLVG---YCPQEDALDDLVTVE 2352
Cdd:PRK14267    20 IKGVDLKIPQNGVFALMGPSGCGKSTLLRTF---------NRLL--ELNEEARVEGEVRLFGrniYSPDVDPIEVRREVG 88
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2353 ---------EHLYFYARVH-GI-------PEKDIKETVHKLLRRLHLM-PFKDRAT---SMCSYGTKRKLSTALALIGKP 2411
Cdd:PRK14267    89 mvfqypnpfPHLTIYDNVAiGVklnglvkSKKELDERVEWALKKAALWdEVKDRLNdypSNLSGGQRQRLVIARALAMKP 168
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 2412 SILLLDEPSSGMDPKSKRHLWKIISeEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCIG 2474
Cdd:PRK14267   169 KILLMDEPTANIDPVGTAKIEELLF-ELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVG 230
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
2282-2450 9.71e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 54.41  E-value: 9.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2282 GIPA---GECFGLLGVNGAGKTTIFKMLTGDIIPSsgnilirnktgsLGHVDSHSSlvgycpQEDALDDLVTVEEHLYFY 2358
Cdd:COG1245     92 GLPVpkkGKVTGILGPNGIGKSTALKILSGELKPN------------LGDYDEEPS------WDEVLKRFRGTELQDYFK 153
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2359 A-------------RVHGIPeKDIKETVHKLLRR-------------LHLMPFKDRATSMCSYGTKRKLSTALALIGKPS 2412
Cdd:COG1245    154 KlangeikvahkpqYVDLIP-KVFKGTVRELLEKvdergkldelaekLGLENILDRDISELSGGELQRVAIAAALLRDAD 232
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 2462571778 2413 ILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSH 2450
Cdd:COG1245    233 FYFFDEPSSYLDIYQRLNVARLIRELAEEGKYVLVVEH 270
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
2275-2452 9.84e-07

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 52.18  E-value: 9.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI------RNKTGSLGHVDSHsslVGYCPQEDALDDL 2348
Cdd:PRK10908    17 ALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFsghditRLKNREVPFLRRQ---IGMIFQDHHLLMD 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2349 VTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMpfkDRATSM---CSYGTKRKLSTALALIGKPSILLLDEPSSGMDP 2425
Cdd:PRK10908    94 RTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLL---DKAKNFpiqLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDD 170
                          170       180
                   ....*....|....*....|....*..
gi 2462571778 2426 KSKRHLWKIISEEVQNKCSVILTSHSM 2452
Cdd:PRK10908   171 ALSEGILRLFEEFNRVGVTVLMATHDI 197
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
1374-1556 1.15e-06

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 53.76  E-value: 1.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1374 GHITSLLGPNGAGKTttiSMLTGLFGA---SAGTIFVYGK--------------------DIKTD----LHTVRKNMGVc 1426
Cdd:PRK11288   279 GEIVGLFGLVGAGRS---ELMKLLYGAtrrTAGQVYLDGKpidirsprdairagimlcpeDRKAEgiipVHSVADNINI- 354
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1427 mqhdvlfsylTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTglySHRHKRVGTLSGGMKRKLSISIALIGGSRVVILD 1506
Cdd:PRK11288   355 ----------SARRHHLRAGCLINNRWEAENADRFIRSLNIKT---PSREQLIMNLSGGNQQKAILGRWLSEDMKVILLD 421
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1507 EPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK11288   422 EPTRGIDVGAKHEIYNVIYElAAQGVAVLFVSSDLPEVLGVADRIVVMREG 472
PLN03140 PLN03140
ABC transporter G family member; Provisional
1371-1557 1.82e-06

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 53.70  E-value: 1.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1371 FYEGHITSLLGPNGAGKTTTISMLTG--LFGASAGTIFVYGKDIKTDlhTVRKNMGVCMQHDVLFSYLTTKEHLLLYGSI 1448
Cdd:PLN03140   903 FRPGVLTALMGVSGAGKTTLMDVLAGrkTGGYIEGDIRISGFPKKQE--TFARISGYCEQNDIHSPQVTVRESLIYSAFL 980
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1449 KVPHWTKK--------QLHEEVK-RTLKDT--GLYShrhkrVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCS- 1516
Cdd:PLN03140   981 RLPKEVSKeekmmfvdEVMELVElDNLKDAivGLPG-----VTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAa 1055
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462571778 1517 ---RRSIWDVISknkTARTIILSTHH--LDEAEVLsDRIAFLEQGG 1557
Cdd:PLN03140  1056 aivMRTVRNTVD---TGRTVVCTIHQpsIDIFEAF-DELLLMKRGG 1097
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
1343-1559 1.87e-06

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 52.16  E-value: 1.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1343 KDLTVgvalhgvTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGaSAGTIFVYGKDIKT-DLHTVRK 1421
Cdd:cd03289      6 KDLTA-------KYTEGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSvPLQKWRK 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1422 NMGVCMQHDVLFSYlTTKEHLLLYGSikvphWTKkqlhEEVKRTLKDTGLYSHRHKRVG-----------TLSGGMKRKL 1490
Cdd:cd03289     78 AFGVIPQKVFIFSG-TFRKNLDPYGK-----WSD----EEIWKVAEEVGLKSVIEQFPGqldfvlvdggcVLSHGHKQLM 147
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1491 SISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLdEAEVLSDRIAFLEQGGLR 1559
Cdd:cd03289    148 CLARSVLSKAKILLLDEPSAHLDPITYQVIRKTLKQAFADCTVILSEHRI-EAMLECQRFLVIEENKVR 215
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
2275-2429 2.30e-06

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 53.05  E-value: 2.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGycpqedalddlvTVEEH 2354
Cdd:PRK10522   338 SVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDYRKLFS------------AVFTD 405
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 LYFYARVHGiPEKDIKET--VHKLLRRL---HLMPFKDR--ATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKS 2427
Cdd:PRK10522   406 FHLFDQLLG-PEGKPANPalVEKWLERLkmaHKLELEDGriSNLKLSKGQKKRLALLLALAEERDILLLDEWAADQDPHF 484

                   ..
gi 2462571778 2428 KR 2429
Cdd:PRK10522   485 RR 486
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
1354-1513 3.18e-06

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 52.48  E-value: 3.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1354 VTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVyGKDIKtdlhtvrknMGVCMQHDVlf 1433
Cdd:PRK10636   318 VSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL-AKGIK---------LGYFAQHQL-- 385
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1434 SYLTTKEHLLLYGSIKVPHWTKKQLHEEVkrtlkdtGLYSHRHKRV----GTLSGGMKRKLSISIALIGGSRVVILDEPS 1509
Cdd:PRK10636   386 EFLRADESPLQHLARLAPQELEQKLRDYL-------GGFGFQGDKVteetRRFSGGEKARLVLALIVWQRPNLLLLDEPT 458

                   ....
gi 2462571778 1510 TGVD 1513
Cdd:PRK10636   459 NHLD 462
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
1365-1551 3.48e-06

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 49.28  E-value: 3.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1365 DNLNLNFYEGHITSLLGPNGAGKTTTI-SMLTGLFGASAGTifvygkdiktdlhtvRKNMGVCMQHDVLFSYLTtkehll 1443
Cdd:cd03227     12 VPNDVTFGEGSLTIITGPNGSGKSTILdAIGLALGGAQSAT---------------RRRSGVKAGCIVAAVSAE------ 70
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1444 lygsikvphwtkkqlheevkrtlkdtgLYSHRHKrvgtLSGGMKRKLSISIAL----IGGSRVVILDEPSTGVDPCSRRS 1519
Cdd:cd03227     71 ---------------------------LIFTRLQ----LSGGEKELSALALILalasLKPRPLYILDEIDRGLDPRDGQA 119
                          170       180       190
                   ....*....|....*....|....*....|....
gi 2462571778 1520 IWDVISKN--KTARTIILSthHLDEAEVLSDRIA 1551
Cdd:cd03227    120 LAEAILEHlvKGAQVIVIT--HLPELAELADKLI 151
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
2274-2450 3.55e-06

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 50.70  E-value: 3.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2274 IAVNNISIG---------IPAGECFGLLGVNGAGKTTIFKMLTGdIIPSSGNILIRNKtgSLGHVdSHSSLV---GYCPQ 2341
Cdd:PRK03695     1 MQLNDVAVStrlgplsaeVRAGEILHLVGPNGAGKSTLLARMAG-LLPGSGSIQFAGQ--PLEAW-SAAELArhrAYLSQ 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLVTVEEHLYFYaRVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGT-KRKLSTALALIGKPSI------L 2414
Cdd:PRK03695    77 QQTPPFAMPVFQYLTLH-QPDKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEwQRVRLAAVVLQVWPDInpagqlL 155
                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 2462571778 2415 LLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSH 2450
Cdd:PRK03695   156 LLDEPMNSLDVAQQAALDRLLSELCQQGIAVVMSSH 191
GguA NF040905
sugar ABC transporter ATP-binding protein;
1353-1556 3.64e-06

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 52.10  E-value: 3.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1353 GVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGL--FGASAGTIFVYG-----KDIKTDLHtvrknMGV 1425
Cdd:NF040905     6 GITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVypHGSYEGEILFDGevcrfKDIRDSEA-----LGI 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1426 CMQHD--VLFSYLTTKEHLLL------YGSIkvpHWtkKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALI 1497
Cdd:NF040905    81 VIIHQelALIPYLSIAENIFLgnerakRGVI---DW--NETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALS 155
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1498 GGSRVVILDEPSTGVDPCSRRSIWDVIS--KNKTARTIILStHHLDEAEVLSDRIAFLEQG 1556
Cdd:NF040905   156 KDVKLLILDEPTAALNEEDSAALLDLLLelKAQGITSIIIS-HKLNEIRRVADSITVLRDG 215
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
1365-1539 4.65e-06

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 49.91  E-value: 4.65e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1365 DNLNLNFYEGhITSLLGPNGAGKTTTISMLT-GLFGASAGTifvyGKDIKTDLHTVRKNmGVCMQHDVLFS------YLT 1437
Cdd:cd03240     14 ERSEIEFFSP-LTLIVGQNGAGKTTIIEALKyALTGELPPN----SKGGAHDPKLIREG-EVRAQVKLAFEnangkkYTI 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1438 TKEHLLLYGSIKVPHwtkkqlhEEVKRTLKDTglyshrhkrVGTLSGGMKRKLSISIAL------IGGSRVVILDEPSTG 1511
Cdd:cd03240     88 TRSLAILENVIFCHQ-------GESNWPLLDM---------RGRCSGGEKVLASLIIRLalaetfGSNCGILALDEPTTN 151
                          170       180       190
                   ....*....|....*....|....*....|.
gi 2462571778 1512 VDPCSRR-SIWDVIS--KNKTARTIILSTHH 1539
Cdd:cd03240    152 LDEENIEeSLAEIIEerKSQKNFQLIVITHD 182
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
1365-1513 4.70e-06

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 49.80  E-value: 4.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1365 DNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTTKEHLLL 1444
Cdd:PRK13538    18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEYHQDLLYLGHQPGIKTELTALENLRF 97
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 1445 YGSIKVPhwtkkQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVD 1513
Cdd:PRK13538    98 YQRLHGP-----GDDEALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAID 161
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
2275-2424 5.06e-06

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 51.99  E-value: 5.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGdIIPSSGNILIRNKtgSLGHVDSH-----------------SSL-- 2335
Cdd:COG4172    301 AVDGVSLTLRRGETLGLVGESGSGKSTLGLALLR-LIPSEGEIRFDGQ--DLDGLSRRalrplrrrmqvvfqdpfGSLsp 377
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2336 ---VGycpQedalddlvTVEEHLyfyaRVHGIP--EKDIKETVHKLLRRLHLMP-FKDRATSMCSYGTKRKLSTALALIG 2409
Cdd:COG4172    378 rmtVG---Q--------IIAEGL----RVHGPGlsAAERRARVAEALEEVGLDPaARHRYPHEFSGGQRQRIAIARALIL 442
                          170
                   ....*....|....*
gi 2462571778 2410 KPSILLLDEPSSGMD 2424
Cdd:COG4172    443 EPKLLVLDEPTSALD 457
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
2262-2431 5.16e-06

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 51.86  E-value: 5.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLiHKKIIavNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIrnktgslghvdSHSSLVGYCPQ 2341
Cdd:TIGR03719   10 VSKVVPP-KKEIL--KDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARP-----------QPGIKVGYLPQ 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLVTVEEH--------LYFYARVHGIPEK-------------------DIKETV--HKLLRRLHL------MPFK 2386
Cdd:TIGR03719   76 EPQLDPTKTVRENveegvaeiKDALDRFNEISAKyaepdadfdklaaeqaelqEIIDAAdaWDLDSQLEIamdalrCPPW 155
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 2387 DRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKS----KRHL 2431
Cdd:TIGR03719  156 DADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESvawlERHL 204
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
2275-2469 6.42e-06

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 51.27  E-value: 6.42e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgslghVDSHSSLvgycpqeDALDD---LVTV 2351
Cdd:PRK10982   263 SIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKK-----INNHNAN-------EAINHgfaLVTE 330
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2352 EEH---------LYFYARVHGIPE----------KDIKETVHKLLRRLHL-MPFKDRATSMCSYGTKRKLSTALALIGKP 2411
Cdd:PRK10982   331 ERRstgiyayldIGFNSLISNIRNyknkvglldnSRMKSDTQWVIDSMRVkTPGHRTQIGSLSGGNQQKVIIGRWLLTQP 410
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 2412 SILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGK 2469
Cdd:PRK10982   411 EILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGL 468
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
1363-1556 7.13e-06

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 51.39  E-value: 7.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKT----DLHTVRKNMGVCMQ---------H 1429
Cdd:PRK10261   339 AVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTlspgKLQALRRDIQFIFQdpyasldprQ 418
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYLTT-KEHLLLYGsikvphwtkKQLHEEVKRTLKDTGLY-SHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDE 1507
Cdd:PRK10261   419 TVGDSIMEPlRVHGLLPG---------KAAAARVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADE 489
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1508 PSTGVDPCSRRSIWDVISKNKTARTI--ILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK10261   490 AVSALDVSIRGQIINLLLDLQRDFGIayLFISHDMAVVERISHRVAVMYLG 540
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
2266-2451 9.63e-06

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 48.47  E-value: 9.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2266 YQLIHKKIiavNNISIGIPAGECFGLLGVNGAGKTTIFKmltgDIIPSSGNILIRNKTGSLGH-----VDSHSSLV---- 2336
Cdd:cd03238      4 SGANVHNL---QNLDVSIPLNVLVVVTGVSGSGKSTLVN----EGLYASGKARLISFLPKFSRnklifIDQLQFLIdvgl 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2337 GYCPQEDALDDLVTVEehlyfyarvhgipekdiketvhklLRRLHLMPFkdratsmcsygtkrklstaLALIGKPSILLL 2416
Cdd:cd03238     77 GYLTLGQKLSTLSGGE------------------------LQRVKLASE-------------------LFSEPPGTLFIL 113
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2462571778 2417 DEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHS 2451
Cdd:cd03238    114 DEPSTGLHQQDINQLLEVIKGLIDLGNTVILIEHN 148
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
2278-2456 1.17e-05

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 51.06  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTgDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDDlVTVEEHLYF 2357
Cdd:TIGR01271 1237 DLSFSVEGGQRVGLLGRTGSGKSTLLSALL-RLLSTEGEIQIDGVSWNSVTLQTWRKAFGVIPQKVFIFS-GTFRKNLDP 1314
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2358 YARvhgIPEKDIKETVHKLLRRLHLMPFKDR-------ATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRH 2430
Cdd:TIGR01271 1315 YEQ---WSDEEIWKVAEEVGLKSVIEQFPDKldfvlvdGGYVLSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQI 1391
                          170       180
                   ....*....|....*....|....*....
gi 2462571778 2431 LWKIISEEVQNkCSVILTSHSME---ECE 2456
Cdd:TIGR01271 1392 IRKTLKQSFSN-CTVILSEHRVEallECQ 1419
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
2275-2418 1.40e-05

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 50.57  E-value: 1.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2275 AVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgslghVDSHSSlvgycpqeDALDDLVTV--- 2351
Cdd:COG4615    347 TLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQP-----VTADNR--------EAYRQLFSAvfs 413
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 2352 EEHLyfYARVHGIPEKDIKETVHKLLRRLHL---MPFKDRATSmcsygtKRKLSTA----LALI-----GKPsILLLDE 2418
Cdd:COG4615    414 DFHL--FDRLLGLDGEADPARARELLERLELdhkVSVEDGRFS------TTDLSQGqrkrLALLvalleDRP-ILVFDE 483
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
1374-1513 1.61e-05

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 50.49  E-value: 1.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1374 GHITSLLGPNGAGKTT---TISMLTGLFGASAGTIFVY----GKDIKTDLhtvRKNMGVCMQHDVLFSYLTTKEHLLLYG 1446
Cdd:TIGR00956   87 GELTVVLGRPGSGCSTllkTIASNTDGFHIGVEGVITYdgitPEEIKKHY---RGDVVYNAETDVHFPHLTVGETLDFAA 163
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462571778 1447 SIKVPHWTKKQLHEEVKR------TLKDTGLYSHRHKRVGT-----LSGGMKRKLSISIALIGGSRVVILDEPSTGVD 1513
Cdd:TIGR00956  164 RCKTPQNRPDGVSREEYAkhiadvYMATYGLSHTRNTKVGNdfvrgVSGGERKRVSIAEASLGGAKIQCWDNATRGLD 241
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
1376-1563 1.85e-05

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 49.49  E-value: 1.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1376 ITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGK---DI--KTDLHTVRKNMGVCMQHDVLFsylttkehlllygsikv 1450
Cdd:PRK11144    26 ITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRvlfDAekGICLPPEKRRIGYVFQDARLF----------------- 88
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1451 PHWT-KKQLHEEVKRTLKD-----TGLYSHRH--KRV-GTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIW 1521
Cdd:PRK11144    89 PHYKvRGNLRYGMAKSMVAqfdkiVALLGIEPllDRYpGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELL 168
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 2462571778 1522 DVISK-NKTARTIIL-STHHLDEAEVLSDRIAFLEQGGLRCCGS 1563
Cdd:PRK11144   169 PYLERlAREINIPILyVSHSLDEILRLADRVVVLEQGKVKAFGP 212
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
2286-2471 2.10e-05

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 48.24  E-value: 2.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2286 GECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSL----VGYCPQEDALDDLVTVEEHLYFYARV 2361
Cdd:PRK10584    36 GETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKLrakhVGFVFQSFMLIPTLNALENVELPALL 115
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2362 HGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKII-SEEVQ 2440
Cdd:PRK10584   116 RGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLfSLNRE 195
                          170       180       190
                   ....*....|....*....|....*....|.
gi 2462571778 2441 NKCSVILTSHSmEECEALCTRLAIMVNGKFQ 2471
Cdd:PRK10584   196 HGTTLILVTHD-LQLAARCDRRLRLVNGQLQ 225
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
1366-1577 2.61e-05

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 49.94  E-value: 2.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1366 NLNLNFYEGHITSLLGPNGAGKTttiSMLTGLF---GASAGTIFVYGKDI-KTDLHTVRKNMGVCMQHDVLFSYlTTKEH 1441
Cdd:TIGR00957 1304 HINVTIHGGEKVGIVGRTGAGKS---SLTLGLFrinESAEGEIIIDGLNIaKIGLHDLRFKITIIPQDPVLFSG-SLRMN 1379
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1442 LLLYGSIKVPH-WTKKQL-HEEVKRTLKDTGLySHRHKRVG-TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRR 1518
Cdd:TIGR00957 1380 LDPFSQYSDEEvWWALELaHLKTFVSALPDKL-DHECAEGGeNLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDN 1458
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 1519 SIWDVISKNKTARTIILSTHHLDeaeVLSD--RIAFLEQGGLRCCGSPFYLKEAFGDGYHL 1577
Cdd:TIGR00957 1459 LIQSTIRTQFEDCTVLTIAHRLN---TIMDytRVIVLDKGEVAEFGAPSNLLQQRGIFYSM 1516
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
2278-2449 2.75e-05

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 49.91  E-value: 2.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIlirnktgslghvdSHSSLVGYCPQEDALDDlVTVEEHLYF 2357
Cdd:TIGR01271  444 NISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKI-------------KHSGRISFSPQTSWIMP-GTIKDNIIF 509
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2358 yarvhGIPEKDIKET----VHKLLRRLHLMPFKDRATSM-----CSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSK 2428
Cdd:TIGR01271  510 -----GLSYDEYRYTsvikACQLEEDIALFPEKDKTVLGeggitLSGGQRARISLARAVYKDADLYLLDSPFTHLDVVTE 584
                          170       180
                   ....*....|....*....|..
gi 2462571778 2429 RHLW-KIISEEVQNKCSVILTS 2449
Cdd:TIGR01271  585 KEIFeSCLCKLMSNKTRILVTS 606
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
1354-1571 2.81e-05

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 49.42  E-value: 2.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1354 VTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGL--FGASAGTIfVYG---------------------- 1409
Cdd:TIGR03269    6 LTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRI-IYHvalcekcgyverpskvgepcpv 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1410 -----KDIKTDL--------HTVRKNMGVCMQHDvlfsylttkehLLLYGSIKVPHWTKKQLHE-------EVKRTLK-- 1467
Cdd:TIGR03269   85 cggtlEPEEVDFwnlsdklrRRIRKRIAIMLQRT-----------FALYGDDTVLDNVLEALEEigyegkeAVGRAVDli 153
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1468 DTGLYSHRHKRVG-TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAE 1544
Cdd:TIGR03269  154 EMVQLSHRITHIArDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEavKASGISMVLTSHWPEVIE 233
                          250       260
                   ....*....|....*....|....*..
gi 2462571778 1545 VLSDRIAFLEQGGLRCCGSPFYLKEAF 1571
Cdd:TIGR03269  234 DLSDKAIWLENGEIKEEGTPDEVVAVF 260
PLN03232 PLN03232
ABC transporter C family member; Provisional
2276-2450 3.39e-05

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 49.59  E-value: 3.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2276 VNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPS-SGNILIRnktGSlghvdshsslVGYCPQEDALDDlVTVEEH 2354
Cdd:PLN03232   633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAeTSSVVIR---GS----------VAYVPQVSWIFN-ATVREN 698
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2355 LYFYARVHgiPEKDIKET-VHKLLRRLHLMPFKDRAT-----SMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSK 2428
Cdd:PLN03232   699 ILFGSDFE--SERYWRAIdVTALQHDLDLLPGRDLTEigergVNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVA 776
                          170       180
                   ....*....|....*....|...
gi 2462571778 2429 RHLW-KIISEEVQNKCSVILTSH 2450
Cdd:PLN03232   777 HQVFdSCMKDELKGKTRVLVTNQ 799
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
2282-2450 3.54e-05

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 49.04  E-value: 3.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2282 GIPA---GECFGLLGVNGAGKTTIFKMLTGDIIPssgnilirnktgSLGHVDSHSSlvgycpQEDALDDLVTVEEHLYFY 2358
Cdd:PRK13409    92 GLPIpkeGKVTGILGPNGIGKTTAVKILSGELIP------------NLGDYEEEPS------WDEVLKRFRGTELQNYFK 153
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2359 A-------------RVHGIPeKDIKETVHKLLR-------------RLHLMPFKDRATSMCSYGTKRKLSTALALIGKPS 2412
Cdd:PRK13409   154 KlyngeikvvhkpqYVDLIP-KVFKGKVRELLKkvdergkldevveRLGLENILDRDISELSGGELQRVAIAAALLRDAD 232
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 2462571778 2413 ILLLDEPSSGMDPKSKRHLWKIISEEVQNKcSVILTSH 2450
Cdd:PRK13409   233 FYFFDEPTSYLDIRQRLNVARLIRELAEGK-YVLVVEH 269
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
1302-1541 4.41e-05

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 49.14  E-value: 4.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1302 EVKPEKSNGLMFTNIMMQNTNPSASKTSPeymfsSNIEPEPKDLTVGVALHGvtkiygsKVAVDNLNLNFYEGHITSLLG 1381
Cdd:TIGR01271 1185 EPRPSGGGGKYQLSTVLVIENPHAQKCWP-----SGGQMDVQGLTAKYTEAG-------RAVLQDLSFSVEGGQRVGLLG 1252
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1382 PNGAGKTTTISMLTGLFgASAGTIFVYGKDIKT-DLHTVRKNMGVCMQHDVLFSYlTTKEHLLLYgsikvPHWTKkqlhE 1460
Cdd:TIGR01271 1253 RTGSGKSTLLSALLRLL-STEGEIQIDGVSWNSvTLQTWRKAFGVIPQKVFIFSG-TFRKNLDPY-----EQWSD----E 1321
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1461 EVKRTLKDTGLYSHRHKRVG-----------TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKT 1529
Cdd:TIGR01271 1322 EIWKVAEEVGLKSVIEQFPDkldfvlvdggyVLSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQIIRKTLKQSFS 1401
                          250
                   ....*....|..
gi 2462571778 1530 ARTIILSTHHLD 1541
Cdd:TIGR01271 1402 NCTVILSEHRVE 1413
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
2262-2424 5.22e-05

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 47.61  E-value: 5.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQlihkKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSS-----LV 2336
Cdd:PRK11701    12 LTKLYG----PRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDLYALSEaerrrLL 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2337 ----GYCPQeDALDDL---VT----VEEHLYFY-ARVHGipekDIKETVHKLLRRLHLMPFK-DRATSMCSYGTKRKLST 2403
Cdd:PRK11701    88 rtewGFVHQ-HPRDGLrmqVSaggnIGERLMAVgARHYG----DIRATAGDWLERVEIDAARiDDLPTTFSGGMQQRLQI 162
                          170       180
                   ....*....|....*....|.
gi 2462571778 2404 ALALIGKPSILLLDEPSSGMD 2424
Cdd:PRK11701   163 ARNLVTHPRLVFMDEPTGGLD 183
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
2394-2454 5.48e-05

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 47.34  E-value: 5.48e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 2394 SYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKII-SEEVQNKCSVILTSHSMEE 2454
Cdd:PRK14258   152 SGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIqSLRLRSELTMVIVSHNLHQ 213
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
2269-2474 6.57e-05

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 48.31  E-value: 6.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2269 IHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILI---RNKTGSLGHVDSHSSLVGYCPQED-- 2343
Cdd:PRK10261   333 VTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFngqRIDTLSPGKLQALRRDIQFIFQDPya 412
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2344 ALDDLVTVEEHLYFYARVHGI-PEKDIKETVHKLLRRLHLMPFKD-RATSMCSYGTKRKLSTALALIGKPSILLLDEPSS 2421
Cdd:PRK10261   413 SLDPRQTVGDSIMEPLRVHGLlPGKAAAARVAWLLERVGLLPEHAwRYPHEFSGGQRQRICIARALALNPKVIIADEAVS 492
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2422 GMDPKSKRHLWKIISeEVQNKCSV--ILTSHSMEECEALCTRLAIMVNGKFQCIG 2474
Cdd:PRK10261   493 ALDVSIRGQIINLLL-DLQRDFGIayLFISHDMAVVERISHRVAVMYLGQIVEIG 546
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
1366-1541 6.65e-05

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 46.40  E-value: 6.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1366 NLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDI----KTDLHTVRKNMGVCMQhdvlfsyLTTKEH 1441
Cdd:PRK13541    18 DLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNInniaKPYCTYIGHNLGLKLE-------MTVFEN 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1442 LLLYGSIkvphwtkKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIW 1521
Cdd:PRK13541    91 LKFWSEI-------YNSAETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLN 163
                          170       180
                   ....*....|....*....|
gi 2462571778 1522 DVISKNKTARTIILSTHHLD 1541
Cdd:PRK13541   164 NLIVMKANSGGIVLLSSHLE 183
PLN03130 PLN03130
ABC transporter C family member; Provisional
2278-2448 7.40e-05

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 48.58  E-value: 7.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIP-SSGNILIRNKtgslghvdshsslVGYCPQEDALDDlVTVEEHLY 2356
Cdd:PLN03130   635 NINLDVPVGSLVAIVGSTGEGKTSLISAMLGELPPrSDASVVIRGT-------------VAYVPQVSWIFN-ATVRDNIL 700
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2357 FyarvhGIP------EKDIKetVHKLLRRLHLMPFKD------RATSMcSYGTKRKLSTALALIGKPSILLLDEPSSGMD 2424
Cdd:PLN03130   701 F-----GSPfdperyERAID--VTALQHDLDLLPGGDlteigeRGVNI-SGGQKQRVSMARAVYSNSDVYIFDDPLSALD 772
                          170       180
                   ....*....|....*....|....*
gi 2462571778 2425 PKSKRHLW-KIISEEVQNKCSVILT 2448
Cdd:PLN03130   773 AHVGRQVFdKCIKDELRGKTRVLVT 797
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
1363-1556 1.32e-04

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 47.03  E-value: 1.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTdlHTV--------------RKNMGVCMQ 1428
Cdd:PRK10982   263 SIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINN--HNAneainhgfalvteeRRSTGIYAY 340
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1429 HDVLFSYLTT--KEHLLLYGSIKvphwtKKQLHEEVKRTLKDTGLYSHRHK-RVGTLSGGMKRKLSISIALIGGSRVVIL 1505
Cdd:PRK10982   341 LDIGFNSLISniRNYKNKVGLLD-----NSRMKSDTQWVIDSMRVKTPGHRtQIGSLSGGNQQKVIIGRWLLTQPEILML 415
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462571778 1506 DEPSTGVDPCSRRSIWDVISK-NKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK10982   416 DEPTRGIDVGAKFEIYQLIAElAKKDKGIIIISSEMPELLGITDRILVMSNG 467
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
1373-1509 1.34e-04

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 47.47  E-value: 1.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1373 EGHITSLLGPNGAGKTTTISMLTGL----FGAsagtifvYGKDIKTD--LHTVRKNmgvcmqhdVLFSYLTTkehllLY- 1445
Cdd:COG1245     98 KGKVTGILGPNGIGKSTALKILSGElkpnLGD-------YDEEPSWDevLKRFRGT--------ELQDYFKK-----LAn 157
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1446 GSIKVPHwtKKQLHEEVKRTLKDT---------------------GLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:COG1245    158 GEIKVAH--KPQYVDLIPKVFKGTvrellekvdergkldelaeklGLENILDRDISELSGGELQRVAIAAALLRDADFYF 235

                   ....*
gi 2462571778 1505 LDEPS 1509
Cdd:COG1245    236 FDEPS 240
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
2266-2450 1.69e-04

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 44.27  E-value: 1.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2266 YQLIHKKIIAVNNIsIGIPAGECFGLLGVNGAGKTTIFKmltgDIIpssgnilirnktgslghvdshsslvgycpqedal 2345
Cdd:cd03227      2 IVLGRFPSYFVPND-VTFGEGSLTIITGPNGSGKSTILD----AIG---------------------------------- 42
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2346 ddLVTveehlyFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRatsmCSYGTKRKLSTALALIG---KPSIL-LLDEPSS 2421
Cdd:cd03227     43 --LAL------GGAQSATRRRSGVKAGCIVAAVSAELIFTRLQ----LSGGEKELSALALILALaslKPRPLyILDEIDR 110
                          170       180
                   ....*....|....*....|....*....
gi 2462571778 2422 GMDPKSKRHLWKIISEEVQNKCSVILTSH 2450
Cdd:cd03227    111 GLDPRDGQALAEAILEHLVKGAQVIVITH 139
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
2268-2473 1.91e-04

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 46.70  E-value: 1.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2268 LIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTG--------------DIIPSSGNILIRNktgSLGHVDSHS 2333
Cdd:PRK09700   271 VTSRDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGvdkraggeirlngkDISPRSPLDAVKK---GMAYITESR 347
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2334 SLVGYCP-----QEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRrLHLMPFKDRATSMcSYGTKRKLSTALALI 2408
Cdd:PRK09700   348 RDNGFFPnfsiaQNMAISRSLKDGGYKGAMGLFHEVDEQRTAENQRELLA-LKCHSVNQNITEL-SGGNQQKVLISKWLC 425
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462571778 2409 GKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGKFQCI 2473
Cdd:PRK09700   426 CCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQI 490
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
2278-2477 2.76e-04

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 45.23  E-value: 2.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTgDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDDlVTVEEHLYF 2357
Cdd:cd03289     22 NISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGDIQIDGVSWNSVPLQKWRKAFGVIPQKVFIFS-GTFRKNLDP 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2358 YARVHgipEKDIKETVHKLLRRLHLMPFKDR-------ATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRH 2430
Cdd:cd03289    100 YGKWS---DEEIWKVAEEVGLKSVIEQFPGQldfvlvdGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQV 176
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2462571778 2431 LWKIISEEVQNkCSVILTSHSMeecEAL--CTRLAIMVNGKFQCIGSLQ 2477
Cdd:cd03289    177 IRKTLKQAFAD-CTVILSEHRI---EAMleCQRFLVIEENKVRQYDSIQ 221
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
1377-1550 4.35e-04

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 45.79  E-value: 4.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1377 TSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDL---------------------------------HTVRKNM 1423
Cdd:PTZ00265  1197 TAIVGETGSGKSTVMSLLMRFYDLKNDHHIVFKNEHTNDMtneqdyqgdeeqnvgmknvnefsltkeggsgedSTVFKNS 1276
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1424 GVCMQHDV------------LFSyLTTKEHLLLYGSI--KVPHWTKKQLHEEVKRTLK----DTGLYSHRHK---RVG-- 1480
Cdd:PTZ00265  1277 GKILLDGVdicdynlkdlrnLFS-IVSQEPMLFNMSIyeNIKFGKEDATREDVKRACKfaaiDEFIESLPNKydtNVGpy 1355
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 1481 --TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVIS--KNKTARTIILSTHHLDEAEvLSDRI 1550
Cdd:PTZ00265  1356 gkSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVdiKDKADKTIITIAHRIASIK-RSDKI 1428
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
1351-1397 4.95e-04

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 45.49  E-value: 4.95e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 1351 LHGVTKIYGS-KVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGL 1397
Cdd:PRK11819     9 MNRVSKVVPPkKQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGV 56
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
2241-2317 5.97e-04

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 45.33  E-value: 5.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2241 RAERLRVE------------SGAAEFDLVQLycltkTYQLIHKKIiaVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTG 2308
Cdd:PRK11147   295 RSERREVMgtakmqveeasrSGKIVFEMENV-----NYQIDGKQL--VKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLG 367

                   ....*....
gi 2462571778 2309 DIIPSSGNI 2317
Cdd:PRK11147   368 QLQADSGRI 376
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
2283-2487 6.28e-04

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 42.94  E-value: 6.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2283 IPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTgslghvdshsslVGYCPQEDALddlvtveehlyfyarvh 2362
Cdd:cd03222     22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGIT------------PVYKPQYIDL----------------- 72
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2363 gipekdiketvhkllrrlhlmpfkdratsmcSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISE-EVQN 2441
Cdd:cd03222     73 -------------------------------SGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRlSEEG 121
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462571778 2442 KCSVILTSHSMEECEALCTRLAIM-----VNGKFQCIGSLQHIKSRFGRGF 2487
Cdd:cd03222    122 KKTALVVEHDLAVLDYLSDRIHVFegepgVYGIASQPKGTREGINRFLRGY 172
YbjD COG3593
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...
2342-2453 6.89e-04

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];


Pssm-ID: 442812 [Multi-domain]  Cd Length: 359  Bit Score: 44.61  E-value: 6.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2342 EDALDDLVT-VEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMpFKDRAT---SMCSYGTKRKLSTALALI-------GK 2410
Cdd:COG3593    109 KEALKALNElLSEYLKELLDGLDLELELSLDELEDLLKSLSLR-IEDGKElplDRLGSGFQRLILLALLSAlaelkraPA 187
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 2462571778 2411 PSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSME 2453
Cdd:COG3593    188 NPILLIEEPEAHLHPQAQRRLLKLLKELSEKPNQVIITTHSPH 230
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
2262-2431 1.00e-03

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 44.34  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2262 LTKTYQLiHKKIIavNNISIGIPAGECFGLLGVNGAGKTTIFKML-------TGDIIPSSGnilIRnktgslghvdshss 2334
Cdd:PRK11819    12 VSKVVPP-KKQIL--KDISLSFFPGAKIGVLGLNGAGKSTLLRIMagvdkefEGEARPAPG---IK-------------- 71
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2335 lVGYCPQEDALDDLVTVEEHL---------------YFYARvHGIPEKDIKETV---------------HKLLRRLHL-M 2383
Cdd:PRK11819    72 -VGYLPQEPQLDPEKTVRENVeegvaevkaaldrfnEIYAA-YAEPDADFDALAaeqgelqeiidaadaWDLDSQLEIaM 149
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462571778 2384 -----PFKDRATSMCSYGTKRKLstALA--LIGKPSILLLDEPSSGMDPKS----KRHL 2431
Cdd:PRK11819   150 dalrcPPWDAKVTKLSGGERRRV--ALCrlLLEKPDMLLLDEPTNHLDAESvawlEQFL 206
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
1329-1412 1.07e-03

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 44.40  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1329 SPEYMFSSNIEPEPKDLTVGVALHGVTKIY-----GSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAG 1403
Cdd:COG4615    308 AAEPAAADAAAPPAPADFQTLELRGVTYRYpgedgDEGFTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESG 387

                   ....*....
gi 2462571778 1404 TIFVYGKDI 1412
Cdd:COG4615    388 EILLDGQPV 396
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
2278-2449 1.15e-03

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 43.31  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2278 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNIlirnktgslghvdSHSSLVGYCPQEDALDDlVTVEEHLYF 2357
Cdd:cd03291     55 NINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKI-------------KHSGRISFSSQFSWIMP-GTIKENIIF 120
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2358 ------YARVHGIPEKDIKETVHKLlrrlhlmPFKDRATS-----MCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPK 2426
Cdd:cd03291    121 gvsydeYRYKSVVKACQLEEDITKF-------PEKDNTVLgeggiTLSGGQRARISLARAVYKDADLYLLDSPFGYLDVF 193
                          170       180
                   ....*....|....*....|....
gi 2462571778 2427 SKRHLW-KIISEEVQNKCSVILTS 2449
Cdd:cd03291    194 TEKEIFeSCVCKLMANKTRILVTS 217
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
1351-1397 1.18e-03

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 44.16  E-value: 1.18e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 2462571778 1351 LHGVTKIYGSKVAV-DNLNLNFYEGHITSLLGPNGAGKTTTISMLTGL 1397
Cdd:TIGR03719    7 MNRVSKVVPPKKEIlKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGV 54
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
1363-1559 1.20e-03

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 44.11  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIfvygkDIKTDLHTVRKNMGVCMQhdvlfsyLTTKEHL 1442
Cdd:PRK13545    39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTV-----DIKGSAALIAISSGLNGQ-------LTGIENI 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1443 LLYGSIKvpHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEP-STGVDPCSRRSIW 1521
Cdd:PRK13545   107 ELKGLMM--GLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEAlSVGDQTFTKKCLD 184
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 2462571778 1522 DVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLR 1559
Cdd:PRK13545   185 KMNEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVK 222
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1348-1424 1.41e-03

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 43.68  E-value: 1.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1348 GVALHGVTKIYGSKV-AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIkTDL---------- 1416
Cdd:PRK11650     3 GLKLQAVRKSYDGKTqVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVV-NELepadrdiamv 81
                           90
                   ....*....|....*..
gi 2462571778 1417 --------H-TVRKNMG 1424
Cdd:PRK11650    82 fqnyalypHmSVRENMA 98
hmuV PRK13547
heme ABC transporter ATP-binding protein;
2270-2424 2.20e-03

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 42.51  E-value: 2.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2270 HKKIIavNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPS--------SGNILIRNKtgSLGHVDSH--SSLVGYC 2339
Cdd:PRK13547    13 HRAIL--RDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGE--PLAAIDAPrlARLRAVL 88
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 2340 PQED------ALDDLVTVEEhlYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALAL------ 2407
Cdd:PRK13547    89 PQAAqpafafSAREIVLLGR--YPHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLaqlwpp 166
                          170       180
                   ....*....|....*....|
gi 2462571778 2408 ---IGKPSILLLDEPSSGMD 2424
Cdd:PRK13547   167 hdaAQPPRYLLLDEPTAALD 186
COG1106 COG1106
ATPase/GTPase, AAA15 family [General function prediction only];
2394-2453 2.88e-03

ATPase/GTPase, AAA15 family [General function prediction only];


Pssm-ID: 440723 [Multi-domain]  Cd Length: 330  Bit Score: 42.34  E-value: 2.88e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462571778 2394 SYGTKRKLSTALALIG---KPSILLLDEPSSGMDPKSKRHLWKIISEEVQNK-CSVILTSHSME 2453
Cdd:COG1106    204 SDGTKRLLALAGALLDalaKGGVLLIDEIEASLHPSLLRKLLKLFLDLANKNnAQLIFTTHSTE 267
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
1373-1529 3.72e-03

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 42.49  E-value: 3.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1373 EGHITSLLGPNGAGKTTTISMLTGL----FG-------------ASAGTIF------VYGKDIKtdlhTVRKNMGVcmqh 1429
Cdd:PRK13409    98 EGKVTGILGPNGIGKTTAVKILSGElipnLGdyeeepswdevlkRFRGTELqnyfkkLYNGEIK----VVHKPQYV---- 169
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1430 DVLFSYL--TTKEHLllygsIKVphwTKKQLHEEVKRTLkdtGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDE 1507
Cdd:PRK13409   170 DLIPKVFkgKVRELL-----KKV---DERGKLDEVVERL---GLENILDRDISELSGGELQRVAIAAALLRDADFYFFDE 238
                          170       180
                   ....*....|....*....|....*
gi 2462571778 1508 PSTGVDPCSRRSIWDVI---SKNKT 1529
Cdd:PRK13409   239 PTSYLDIRQRLNVARLIrelAEGKY 263
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
1363-1553 4.07e-03

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 42.10  E-value: 4.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1363 AVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGL----FGASAGTIFVYGKD-IKTDLHTVRKNMG--VCMQHDVLFSY 1435
Cdd:PRK15093    22 AVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVtkdnWRVTADRMRFDDIDlLRLSPRERRKLVGhnVSMIFQEPQSC 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462571778 1436 LTTKEHLLLYGSIKVPHWTKK-----QLHEEVKRT---LKDTGLYSHR---HKRVGTLSGGMKRKLSISIALIGGSRVVI 1504
Cdd:PRK15093   102 LDPSERVGRQLMQNIPGWTYKgrwwqRFGWRKRRAielLHRVGIKDHKdamRSFPYELTEGECQKVMIAIALANQPRLLI 181
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462571778 1505 LDEPSTGVDPCSRRSIWDVISK----NKTarTIILSTHHLDEAEVLSDRIAFL 1553
Cdd:PRK15093   182 ADEPTNAMEPTTQAQIFRLLTRlnqnNNT--TILLISHDLQMLSQWADKINVL 232
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
1482-1556 4.41e-03

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 42.54  E-value: 4.41e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462571778 1482 LSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVIS--KNKTARTIILSTHHLDEAEVLSDRIAFLEQG 1556
Cdd:PRK10261   169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKvlQKEMSMGVIFITHDMGVVAEIADRVLVMYQG 245
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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