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Conserved domains on  [gi|2462505437|ref|XP_054190765|]
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tetratricopeptide repeat protein 24 isoform X7 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
121-408 6.24e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.41  E-value: 6.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 121 FNVALAYHALGELPQALAWYHRALGHYQpqgDQGEAWAKMGACYQALGQPELAAHCLQEAsqayaqerqlraaalalgaa 200
Cdd:COG0457    12 NNLGLAYRRLGRYEEAIEDYEKALELDP---DDAEALYNLGLAYLRLGRYEEALADYEQA-------------------- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 201 agcmlksgrhrvgevvqvLEKSRRLAErstgrrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRNLG 280
Cdd:COG0457    69 ------------------LELDPDDAE----------ALNNLGLALQALGRYEEALEDYDKALEL---DPDDAEALYNLG 117

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 281 MAHNALGNYQEAREFHQKAADLHGSVGQRWEqgrsfgSLAFALSQLGDHKAARDNYLHALQAARDsgDMKGQWQACEGLG 360
Cdd:COG0457   118 LALLELGRYDEAIEAYERALELDPDDADALY------NLGIALEKLGRYEEALELLEKLEAAALA--ALLAAALGEAALA 189

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2462505437 361 AAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQ 408
Cdd:COG0457   190 LAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAA 237
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 29-182 3.79e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.32  E-value: 3.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  29 WLRQEASIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHpe 108
Cdd:COG3914    71 AAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEAL---------FNLGNLLLALGRLEEALAALRRAL-- 139

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462505437 109 ekAQGRRHGDQCFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQ 182
Cdd:COG3914   140 --ALNPDFAEAYLNLGEALRRLGRLEEAIAALRRAL---ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
121-408 6.24e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.41  E-value: 6.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 121 FNVALAYHALGELPQALAWYHRALGHYQpqgDQGEAWAKMGACYQALGQPELAAHCLQEAsqayaqerqlraaalalgaa 200
Cdd:COG0457    12 NNLGLAYRRLGRYEEAIEDYEKALELDP---DDAEALYNLGLAYLRLGRYEEALADYEQA-------------------- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 201 agcmlksgrhrvgevvqvLEKSRRLAErstgrrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRNLG 280
Cdd:COG0457    69 ------------------LELDPDDAE----------ALNNLGLALQALGRYEEALEDYDKALEL---DPDDAEALYNLG 117

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 281 MAHNALGNYQEAREFHQKAADLHGSVGQRWEqgrsfgSLAFALSQLGDHKAARDNYLHALQAARDsgDMKGQWQACEGLG 360
Cdd:COG0457   118 LALLELGRYDEAIEAYERALELDPDDADALY------NLGIALEKLGRYEEALELLEKLEAAALA--ALLAAALGEAALA 189

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2462505437 361 AAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQ 408
Cdd:COG0457   190 LAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAA 237
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 29-182 3.79e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.32  E-value: 3.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  29 WLRQEASIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHpe 108
Cdd:COG3914    71 AAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEAL---------FNLGNLLLALGRLEEALAALRRAL-- 139

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462505437 109 ekAQGRRHGDQCFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQ 182
Cdd:COG3914   140 --ALNPDFAEAYLNLGEALRRLGRLEEAIAALRRAL---ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
TPR_12 pfam13424
Tetratricopeptide repeat;
271-345 7.04e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 49.69  E-value: 7.04e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462505437 271 EQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSV--GQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARD 345
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 353-381 2.66e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 2.66e-03
                           10        20
                   ....*....|....*....|....*....
gi 2462505437  353 WQACEGLGAAAARLGQYDQALKYYKEALA 381
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALE 29
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 54-136 9.48e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.53  E-value: 9.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  54 EALNNFQRAFLLASKAPQTRDTpvlqacafnLGAAYVETGDPARGLELLLRAhpeeKAQGRRHGDQCFNVALAYHALGEL 133
Cdd:TIGR02917 821 RALEYAERALKLAPNIPAILDT---------LGWLLVEKGEADRALPLLRKA----VNIAPEAAAIRYHLALALLATGRK 887


                  ...
gi 2462505437 134 PQA 136
Cdd:TIGR02917 888 AEA 890
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
121-408 6.24e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.41  E-value: 6.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 121 FNVALAYHALGELPQALAWYHRALGHYQpqgDQGEAWAKMGACYQALGQPELAAHCLQEAsqayaqerqlraaalalgaa 200
Cdd:COG0457    12 NNLGLAYRRLGRYEEAIEDYEKALELDP---DDAEALYNLGLAYLRLGRYEEALADYEQA-------------------- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 201 agcmlksgrhrvgevvqvLEKSRRLAErstgrrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRNLG 280
Cdd:COG0457    69 ------------------LELDPDDAE----------ALNNLGLALQALGRYEEALEDYDKALEL---DPDDAEALYNLG 117

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 281 MAHNALGNYQEAREFHQKAADLHGSVGQRWEqgrsfgSLAFALSQLGDHKAARDNYLHALQAARDsgDMKGQWQACEGLG 360
Cdd:COG0457   118 LALLELGRYDEAIEAYERALELDPDDADALY------NLGIALEKLGRYEEALELLEKLEAAALA--ALLAAALGEAALA 189

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2462505437 361 AAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQ 408
Cdd:COG0457   190 LAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAA 237
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 157-382 1.41e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.05  E-value: 1.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 157 WAKMGACYQALGQPELAAHCLQEASQAYAQERQLRAaalalgaaagcMLKSGRHRVGEVVQVLEKSRRLAERSTGRrllG 236
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHL-----------ALGNLYRRRGEYDRAIRIHQKLLERDPDR---A 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 237 HLYNDLGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQgrsf 316
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLLEL---DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCE---- 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462505437 317 gsLAFALSQLGDHKAARDNYLHALQAARDSGDmkgqwqACEGLGAAAARLGQYDQALKYYKEALAQ 382
Cdd:COG2956   150 --LAELYLEQGDYDEAIEALEKALKLDPDCAR------ALLLLAELYLEQGDYEEAIAALERALEQ 207
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 42-382 3.53e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.51  E-value: 3.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  42 AGHGALQAGQNHEALNNFQRAFLLASKA----PQTRDTpvlqacAFNLGAAYVETGDPARGLELLLRAHpeekAQGRRHG 117
Cdd:COG2956     7 AALGWYFKGLNYLLNGQPDKAIDLLEEAleldPETVEA------HLALGNLYRRRGEYDRAIRIHQKLL----ERDPDRA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 118 DQCFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQErqlraaalal 197
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLL---ELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN---------- 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 198 gaaagcmlksgrhrvgevvqvleksrrlaerstgrrllGHLYNDLGLGYSQLQLFPLAVEAFLQAL---PLCwvpgeqAT 274
Cdd:COG2956   144 --------------------------------------AHAYCELAELYLEQGDYDEAIEALEKALkldPDC------AR 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 275 VLRNLGMAHNALGNYQEAREFHQKAADLHGsvgqrwEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMkgqwq 354
Cdd:COG2956   180 ALLLLAELYLEQGDYEEAIAALERALEQDP------DYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL----- 248

                         330       340
                  ....*....|....*....|....*...
gi 2462505437 355 acEGLGAAAARLGQYDQALKYYKEALAQ 382
Cdd:COG2956   249 --LALADLLERKEGLEAALALLERQLRR 274
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 29-182 3.79e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.32  E-value: 3.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  29 WLRQEASIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHpe 108
Cdd:COG3914    71 AAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEAL---------FNLGNLLLALGRLEEALAALRRAL-- 139

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462505437 109 ekAQGRRHGDQCFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQ 182
Cdd:COG3914   140 --ALNPDFAEAYLNLGEALRRLGRLEEAIAALRRAL---ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 155-381 6.06e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.55  E-value: 6.06e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 155 EAWAKMGACYQALGQPELAAHCLQEASQAYAQERQLRAAALALGAaagcmLKSGRHRVGEVVQVLEKSRRLAERSTGRRL 234
Cdd:COG3914     2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALL-----LLAALAEAAAAALLALAAGEAAAAAAALLL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 235 LGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCwvpGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGsvgqrwEQGR 314
Cdd:COG3914    77 LAALLELAALLLQALGRYEEALALYRRALALN---PDNAEALFNLGNLLLALGRLEEALAALRRALALNP------DFAE 147

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462505437 315 SFGSLAFALSQLGDHKAARDNYLHALQAARDsgdmkgQWQACEGLGAAAARLGQYDQALKYYKEALA 381
Cdd:COG3914   148 AYLNLGEALRRLGRLEEAIAALRRALELDPD------NAEALNNLGNALQDLGRLEEAIAAYRRALE 208
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 41-328 7.47e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.16  E-value: 7.47e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  41 RAGHGALQAGQNHEALNNFQRAFLLASKAPQTRDTPVLQACAFNLGAAYVETGDPARGLELLLRAHPEEKAQGRRHGDQC 120
Cdd:COG3914     2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 121 FNVALAYHALGELPQALAWYHRALGHyqpQGDQGEAWAKMGACYQALGQPELAAHCLQEAsqayaqerqlraaalalgaa 200
Cdd:COG3914    82 ELAALLLQALGRYEEALALYRRALAL---NPDNAEALFNLGNLLLALGRLEEALAALRRA-------------------- 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 201 agcmlksgrhrvgevvqvLEKSRRLAErstgrrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLCwvpGEQATVLRNLG 280
Cdd:COG3914   139 ------------------LALNPDFAE----------AYLNLGEALRRLGRLEEAIAALRRALELD---PDNAEALNNLG 187

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2462505437 281 MAHNALGNYQEAREFHQKAADLHGsvgqrwEQGRSFGSLAFALSQLGD 328
Cdd:COG3914   188 NALQDLGRLEEAIAAYRRALELDP------DNADAHSNLLFALRQACD 229
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
83-373 1.01e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.86  E-value: 1.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  83 FNLGAAYVETGDPARGLELLLRAHpeekAQGRRHGDQCFNVALAYHALGELPQALAWYHRALgHYQPqgDQGEAWAKMGA 162
Cdd:COG0457    12 NNLGLAYRRLGRYEEAIEDYEKAL----ELDPDDAEALYNLGLAYLRLGRYEEALADYEQAL-ELDP--DDAEALNNLGL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 163 CYQALGQPELAAHCLQEAsqayaqerqlraaalalgaaagcmlksgrhrvgevvqvLEKSRRLAErstgrrllghLYNDL 242
Cdd:COG0457    85 ALQALGRYEEALEDYDKA--------------------------------------LELDPDDAE----------ALYNL 116

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 243 GLGYSQLQLFPLAVEAFLQALPLCWvpgEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFA 322
Cdd:COG0457   117 GLALLELGRYDEAIEAYERALELDP---DDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAA 193

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462505437 323 LSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQAL 373
Cdd:COG0457   194 EVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYR 244
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 125-353 1.08e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 60.78  E-value: 1.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 125 LAYHALGELPQALAWYHRALGHYQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQERQLRAAALALGAAAGCM 204
Cdd:COG3914     1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 205 LKS------GRHRVGEVVQVLEKSRRLAERSTGrrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRN 278
Cdd:COG3914    81 LELaalllqALGRYEEALALYRRALALNPDNAE------ALFNLGNLLLALGRLEEALAALRRALAL---NPDFAEAYLN 151

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462505437 279 LGMAHNALGNYQEAREFHQKAADLHGsvgqrwEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQW 353
Cdd:COG3914   152 LGEALRRLGRLEEAIAALRRALELDP------DNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
152-411 1.34e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.48  E-value: 1.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 152 DQGEAWAKMGACYQALGQPELAAHCLQEAsqayaqerqlraaalalgaaagcmlksgrhrvgevvqvLEKSRRLAErstg 231
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKA--------------------------------------LELDPDDAE---- 43

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 232 rrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLCwvpGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGsvgqrwE 311
Cdd:COG0457    44 ------ALYNLGLAYLRLGRYEEALADYEQALELD---PDDAEALNNLGLALQALGRYEEALEDYDKALELDP------D 108

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 312 QGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDmkgqwqACEGLGAAAARLGQYDqalkyykEALAQCQKEPDSVR 391
Cdd:COG0457   109 DAEALYNLGLALLELGRYDEAIEAYERALELDPDDAD------ALYNLGIALEKLGRYE-------EALELLEKLEAAAL 175

                         250       260
                  ....*....|....*....|
gi 2462505437 392 ERLVAKLADTVRTRLAQVGL 411
Cdd:COG0457   176 AALLAAALGEAALALAAAEV 195
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 234-382 1.04e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 1.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 234 LLGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCWVPGEQATVLRNLGMAHNAL---GNYQEAREFHQKAADLHGSVGQRW 310
Cdd:COG3914    36 ALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLqalGRYEEALALYRRALALNPDNAEAL 115

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462505437 311 EQgrsfgsLAFALSQLGDHKAARDNYLHALQAARDsgdmkgQWQACEGLGAAAARLGQYDQALKYYKEALAQ 382
Cdd:COG3914   116 FN------LGNLLLALGRLEEALAALRRALALNPD------FAEAYLNLGEALRRLGRLEEAIAALRRALEL 175
TPR_12 pfam13424
Tetratricopeptide repeat;
271-345 7.04e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 49.69  E-value: 7.04e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462505437 271 EQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSV--GQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARD 345
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 271-400 1.03e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.77  E-value: 1.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 271 EQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWeqgrsfGSLAFALSQLGDHKAARDNYLHALqaARDSGDMK 350
Cdd:COG4235    15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADAL------LDLAEALLAAGDTEEAEELLERAL--ALDPDNPE 86

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462505437 351 GQWQacegLGAAAARLGQYDQALKYYKEALAqcQKEPDSVRERLVAKLAD 400
Cdd:COG4235    87 ALYL----LGLAAFQQGDYAEAIAAWQKLLA--LLPADAPARLLEASIAE 130
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
37-180 1.35e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.70  E-value: 1.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  37 QALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHpeekAQGRRH 116
Cdd:COG0457     9 EAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEAL---------YNLGLAYLRLGRYEEALADYEQAL----ELDPDD 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462505437 117 GDQCFNVALAYHALGELPQALAWYHRALGHyqpQGDQGEAWAKMGACYQALGQPELAAHCLQEA 180
Cdd:COG0457    76 AEALNNLGLALQALGRYEEALEDYDKALEL---DPDDAEALYNLGLALLELGRYDEAIEAYERA 136
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
238-381 3.79e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.07  E-value: 3.79e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 238 LYNDLGLGYSQLQLFPLAVEAFLQALPLCwvPgEQATVLRNLGMAHNALGNYQEAREFHQKAADLhgsvgqRWEQGRSFG 317
Cdd:COG4785    75 LYYERGVAYDSLGDYDLAIADFDQALELD--P-DLAEAYNNRGLAYLLLGDYDAALEDFDRALEL------DPDYAYAYL 145

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462505437 318 SLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGL--------------GAAAARLGQYDQALKYYKEALA 381
Cdd:COG4785   146 NRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKldpekalallledwATAYLLQGDTEEARELFKLALA 223
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 35-190 4.39e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.19  E-value: 4.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  35 SIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHPEEKAQGR 114
Cdd:COG2956   109 DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAY---------CELAELYLEQGDYDEAIEALEKALKLDPDCAR 179

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462505437 115 RHgdqcFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQERQL 190
Cdd:COG2956   180 AL----LLLAELYLEQGDYEEAIAALERAL---EQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL 248
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 270-388 7.27e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.57  E-value: 7.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 270 GEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGsvgqrwEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSgdm 349
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDP------DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDE--- 71

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2462505437 350 kgqWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPD 388
Cdd:COG4783    72 ---PEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE 107
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 242-394 1.14e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.03  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 242 LGLGYSQLQLFPLAVEAFLQALPLcwvPGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQgrsfgsLAF 321
Cdd:COG2956    14 KGLNYLLNGQPDKAIDLLEEALEL---DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLE------LAQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 322 ALSQLGDHKAARDNYLHALQAARDSGD----------MKGQWQA-------------------CEgLGAAAARLGQYDQA 372
Cdd:COG2956    85 DYLKAGLLDRAEELLEKLLELDPDDAEalrllaeiyeQEGDWEKaievlerllklgpenahayCE-LAELYLEQGDYDEA 163

                         170       180
                  ....*....|....*....|..
gi 2462505437 373 LKYYKEALaqcQKEPDSVRERL 394
Cdd:COG2956   164 IEALEKAL---KLDPDCARALL 182
TPR_12 pfam13424
Tetratricopeptide repeat;
319-385 2.79e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 42.37  E-value: 2.79e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462505437 319 LAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQAC--EGLGAAAARLGQYDQALKYYKEALAQCQK 385
Cdd:pfam13424   9 LAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATtlLNLGRLYLELGRYEEALELLERALALAEK 77
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 33-187 1.12e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.10  E-value: 1.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  33 EASIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRdtpvlqacaFNLGAAYVETGDPARGLELLLRAHpeekAQ 112
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAF---------ALLGEILLQLGDLDEAIVLLHEAL----EL 67

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462505437 113 GRRHGDQCFNVALAYHALGELPQALAWYHRALGHYQpqgDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQE 187
Cdd:COG4783    68 DPDEPEARLNLGLALLKAGDYDEALALLEKALKLDP---EHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
282-381 1.18e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 1.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 282 AHNALGNYQEAREFHQKAADLHgsvgqrWEQGRSFGSLAFALSQLGDHKAARDnYLHALQAARDSgdmkgqWQACEGLGA 361
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELD------PDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNN------AEALLNLAE 67

                          90       100
                  ....*....|....*....|
gi 2462505437 362 AAARLGQYDQALKYYKEALA 381
Cdd:COG3063    68 LLLELGDYDEALAYLERALE 87
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 232-381 1.35e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.25  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 232 RRLLGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCWVPGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWE 311
Cdd:COG5010    13 YLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYY 92

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 312 qgrsfgSLAFALSQLGDHKAARDNYLHALQAARDSgdmkgqWQACEGLGAAAARLGQYDQALKYYKEALA 381
Cdd:COG5010    93 ------NLALLYSRSGDKDEAKEYYEKALALSPDN------PNAYSNLAALLLSLGQDDEAKAALQRALG 150
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 271-382 2.75e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.95  E-value: 2.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 271 EQATVLRNLGMAHNALGNYQEAREFHQKAADLHGsvgqrwEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDmk 350
Cdd:COG4783    36 DNPEAFALLGEILLQLGDLDEAIVLLHEALELDP------DEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE-- 107

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2462505437 351 gqwqACEGLGAAAARLGQYDQALKYYKEALAQ 382
Cdd:COG4783   108 ----AYLRLARAYRALGRPDEAIAALEKALEL 135
COG3899 COG3899
Predicted ATPase [General function prediction only];
36-451 3.14e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 43.69  E-value: 3.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437   36 IQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRDTPVLQAcafNLGAAYVETGDPARGLELLLRAHPEEkaqgrr 115
Cdd:COG3899    705 ARLLLRAARRALARGAYAEALRYLERALELLPPDPEEEYRLALLL---ELAEALYLAGRFEEAEALLERALAAR------ 775

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  116 hgdqcFNVALAYHALGELPQALAWYHRALGHYQPQGDQGEAWAKMG-ACYQALGQPELAAHCLQEASQAYAQERQLRAAA 194
Cdd:COG3899    776 -----ALAALAALRHGNPPASARAYANLGLLLLGDYEEAYEFGELAlALAERLGDRRLEARALFNLGFILHWLGPLREAL 850

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  195 LALGAAAGCMLKSGRHRVGEVVQVLEKSRRLAERSTGRRLLGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCWVPGEQAT 274
Cdd:COG3899    851 ELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAA 930

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  275 VLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQ 354
Cdd:COG3899    931 LALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAA 1010

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  355 ACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQVGLVQTHTLTSAPGRLQAPGGASQAE 434
Cdd:COG3899   1011 AAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAA 1090

                          410
                   ....*....|....*..
gi 2462505437  435 GTPAKAGSSTAGVQHRS 451
Cdd:COG3899   1091 ALAAAALAAAAAAALAL 1107
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 88-184 8.60e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.82  E-value: 8.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  88 AYVETGDP---ARGLELLLRAHPEEKAQGRRHgdqcFNVALAYHALGELPQALAWYHRALGHYQPQGDQGEAWAKMGACY 164
Cdd:COG1729     2 ALLKAGDYdeaIAAFKAFLKRYPNSPLAPDAL----YWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSY 77

                          90       100
                  ....*....|....*....|
gi 2462505437 165 QALGQPELAAHCLQEASQAY 184
Cdd:COG1729    78 LELGDYDKARATLEELIKKY 97
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
246-345 9.93e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 9.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 246 YSQLQLFPLAVEAFLQALPLcwVPgEQATVLRNLGMAHNALGNYQEAREFhQKAADLHGsvgqrwEQGRSFGSLAFALSQ 325
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALEL--DP-DNADALNNLGLLLLEQGRYDEAIAL-EKALKLDP------NNAEALLNLAELLLE 71

                          90       100
                  ....*....|....*....|
gi 2462505437 326 LGDHKAARDNYLHALQAARD 345
Cdd:COG3063    72 LGDYDEALAYLERALELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 118-303 2.04e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.63  E-value: 2.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 118 DQCFNVALAYHALGELPQALAWYHRALghyQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQERQlraaalal 197
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKAL---ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPE-------- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 198 gaaagcmlksgrhrvgevvqvleksrrlaerstgrrllghLYNDLGLGYSQLQLFPLAVEAFLQALPLCwvpGEQATVLR 277
Cdd:COG4783    74 ----------------------------------------ARLNLGLALLKAGDYDEALALLEKALKLD---PEHPEAYL 110

                         170       180
                  ....*....|....*....|....*.
gi 2462505437 278 NLGMAHNALGNYQEAREFHQKAADLH 303
Cdd:COG4783   111 RLARAYRALGRPDEAIAALEKALELD 136
TPR_1 pfam00515
Tetratricopeptide repeat;
354-380 2.45e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 2.45e-03
                          10        20
                  ....*....|....*....|....*..
gi 2462505437 354 QACEGLGAAAARLGQYDQALKYYKEAL 380
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKAL 28
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 353-381 2.66e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 2.66e-03
                           10        20
                   ....*....|....*....|....*....
gi 2462505437  353 WQACEGLGAAAARLGQYDQALKYYKEALA 381
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALE 29
TPR_10 pfam13374
Tetratricopeptide repeat;
273-303 2.67e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 35.56  E-value: 2.67e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2462505437 273 ATVLRNLGMAHNALGNYQEAREFHQKAADLH 303
Cdd:pfam13374   2 ASSLNNLANALRAQGRYDEAEELLEEALAIR 32
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
47-179 3.38e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.09  E-value: 3.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  47 LQAGQNHEALNNFQRAFllasKAPQTRDTPVLqacaFNLGAAYVETGDPARGLELL---LRAHPEekaqgRRHGDQCFNV 123
Cdd:COG4700   100 LELGRYDEAIELYEEAL----TGIFADDPHIL----LGLAQALFELGRYAEALETLeklIAKNPD-----FKSSDAHLLY 166

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462505437 124 ALAYHALGELPQALAWYHRALGHYqpqgDQGEAWAKMGACYQALGQPELAAHCLQE 179
Cdd:COG4700   167 ARALEALGDLEAAEAELEALARRY----SGPEARYRYAKFLARQGRTAEAKELLEE 218
TPR_12 pfam13424
Tetratricopeptide repeat;
122-186 4.54e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 35.83  E-value: 4.54e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437 122 NVALAYHALGELPQALAWYHRALGHYQPQG-----DQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQ 186
Cdd:pfam13424   8 NLAAVLRRLGRYDEALELLEKALEIARRLLgpdhpLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 273-302 4.57e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 4.57e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 2462505437  273 ATVLRNLGMAHNALGNYQEAREFHQKAADL 302
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALEL 30
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 54-136 9.48e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.53  E-value: 9.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462505437  54 EALNNFQRAFLLASKAPQTRDTpvlqacafnLGAAYVETGDPARGLELLLRAhpeeKAQGRRHGDQCFNVALAYHALGEL 133
Cdd:TIGR02917 821 RALEYAERALKLAPNIPAILDT---------LGWLLVEKGEADRALPLLRKA----VNIAPEAAAIRYHLALALLATGRK 887


                  ...
gi 2462505437 134 PQA 136
Cdd:TIGR02917 888 AEA 890
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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