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Conserved domains on  [gi|2462567384|ref|XP_054177967|]
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zinc finger protein 85 isoform X5 [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
151-512 1.14e-13

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 73.19  E-value: 1.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 151 KPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKC--EECGKTFNRFSTLTTHKIIHTGEKPYKC-KECGKAFNRSSTLTTH 227
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNsKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 228 RKIHTGEKPYKCEECGKAFKQSSNLT--THKIIHTGEKPYK-CKKCGKAFNQSAHL-------------------TTHEV 285
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgNNSSSVNTPQSNSLhpplpanslskdpssnlslLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 286 IHTGEKPYKCEKCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIHTGEKPYKCKECEKAFNQSSKLT 365
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 366 EHKKIHTGE-------KPYECEKCGKAFNQSSNLTRHKKS--HTEE--KPYKCEE--CGKGFKWPSTLTIHKIIHTGEKP 432
Cdd:COG5048   272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 433 YKC--EECGKAFNQSS-----KLTKHKKIHTGEKPYTCE--ECGKAFNQSSNLTKHKRIHTGEKP--YKCEECDKAFKWS 501
Cdd:COG5048   352 AKEklLNSSSKFSPLLnneppQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                         410
                  ....*....|.
gi 2462567384 502 SVLTKHKIIHT 512
Cdd:COG5048   432 YNLIPHKKIHT 442
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
151-512 1.14e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 73.19  E-value: 1.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 151 KPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKC--EECGKTFNRFSTLTTHKIIHTGEKPYKC-KECGKAFNRSSTLTTH 227
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNsKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 228 RKIHTGEKPYKCEECGKAFKQSSNLT--THKIIHTGEKPYK-CKKCGKAFNQSAHL-------------------TTHEV 285
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgNNSSSVNTPQSNSLhpplpanslskdpssnlslLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 286 IHTGEKPYKCEKCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIHTGEKPYKCKECEKAFNQSSKLT 365
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 366 EHKKIHTGE-------KPYECEKCGKAFNQSSNLTRHKKS--HTEE--KPYKCEE--CGKGFKWPSTLTIHKIIHTGEKP 432
Cdd:COG5048   272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 433 YKC--EECGKAFNQSS-----KLTKHKKIHTGEKPYTCE--ECGKAFNQSSNLTKHKRIHTGEKP--YKCEECDKAFKWS 501
Cdd:COG5048   352 AKEklLNSSSKFSPLLnneppQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                         410
                  ....*....|.
gi 2462567384 502 SVLTKHKIIHT 512
Cdd:COG5048   432 YNLIPHKKIHT 442
zf-H2C2_2 pfam13465
Zinc-finger double domain;
475-499 4.75e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 4.75e-04
                          10        20
                  ....*....|....*....|....*
gi 2462567384 475 NLTKHKRIHTGEKPYKCEECDKAFK 499
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
151-512 1.14e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 73.19  E-value: 1.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 151 KPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKC--EECGKTFNRFSTLTTHKIIHTGEKPYKC-KECGKAFNRSSTLTTH 227
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNsKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 228 RKIHTGEKPYKCEECGKAFKQSSNLT--THKIIHTGEKPYK-CKKCGKAFNQSAHL-------------------TTHEV 285
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgNNSSSVNTPQSNSLhpplpanslskdpssnlslLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 286 IHTGEKPYKCEKCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIHTGEKPYKCKECEKAFNQSSKLT 365
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 366 EHKKIHTGE-------KPYECEKCGKAFNQSSNLTRHKKS--HTEE--KPYKCEE--CGKGFKWPSTLTIHKIIHTGEKP 432
Cdd:COG5048   272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 433 YKC--EECGKAFNQSS-----KLTKHKKIHTGEKPYTCE--ECGKAFNQSSNLTKHKRIHTGEKP--YKCEECDKAFKWS 501
Cdd:COG5048   352 AKEklLNSSSKFSPLLnneppQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                         410
                  ....*....|.
gi 2462567384 502 SVLTKHKIIHT 512
Cdd:COG5048   432 YNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
163-491 8.76e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 67.03  E-value: 8.76e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 163 NQSSNLIKHKKIHTGE----KPYKCEECGKTFNRFSTLTTHKIIHTGEKPYKC--KECGKAFNRSSTLTTHRKIHTGEKP 236
Cdd:COG5048    12 NNSVLSSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 237 YkcEECGKAFKQSSNLTTHKIIHTGEKPYKCKKC-GKAFNQSAHLTTHEVIHTGEKPYKCEKCGKAFNHFSHLTTHKIIH 315
Cdd:COG5048    92 D--LNSKSLPLSNSKASSSSLSSSSSNSNDNNLLsSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHP 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 316 TGEKPYKCKEcgkAFKHSSTLTKHKIIHTGEKPYKCKECEKaFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSSNLTRH 395
Cdd:COG5048   170 PLPANSLSKD---PSSNLSLLISSNVSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSP 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 396 KKSHTEEKPYKCEECGKGFKWPSTLTIHKIIHTGE-------KPYKCEECGKAFNQSSKLTKHK--KIHTGE--KPYTCE 464
Cdd:COG5048   246 SSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCP 325

                         330       340
                  ....*....|....*....|....*....
gi 2462567384 465 E--CGKAFNQSSNLTKHKRIHTGEKPYKC 491
Cdd:COG5048   326 YslCGKLFSRNDALKRHILLHTSISPAKE 354
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
158-412 4.25e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.02  E-value: 4.25e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 158 CGKAFNQSSNLIKHKKIHTGEKPYKCEECGKTfNRFSTLTTHKIIHTGEKPYKCKECGKAFNRSSTLTTHRKIHTGEKPY 237
Cdd:COG5048   177 SKDPSSNLSLLISSNVSTSIPSSSENSPLSSS-YSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSS 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 238 KCEECGKAFKQSSNLTTHKIIHTGE-------KPYKCKKCGKAFNQSAHLTTH--EVIHTGE--KPYKC--EKCGKAFNH 304
Cdd:COG5048   256 SASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHlrSVNHSGEslKPFSCpySLCGKLFSR 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 305 FSHLTTHKIIHTGEKPYKCKECGKAFKHS--------STLTKHKIIHTGEKPYKC-KECEKAFNQSSKLTEHKKIHTGEK 375
Cdd:COG5048   336 NDALKRHILLHTSISPAKEKLLNSSSKFSpllnneppQSLQQYKDLKNDKKSETLsNSCIRNFKRDSNLSLHIITHLSFR 415

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 2462567384 376 PYECE--KCGKAFNQSSNLTRHKKSHTEEKPYKCEECGK 412
Cdd:COG5048   416 PYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
67-474 8.68e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.70  E-value: 8.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384  67 KIFQCDKYVKVAHKFSNSNRHEIRHTKKKPFKCTK--CGKSFGMISCLTEHSRIHT-RVNFYKCEECGKAFNWSStltKH 143
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHnNPSDLNSKSLPLSNSKAS---SS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 144 KRIHTGEKPYKCE-ECGKAFNQSSNLIKHKKIHTGEKPYKCEECGKTFNRFSTLTTHKIIHTGEKPYKCKEcgkAFNRSS 222
Cdd:COG5048   109 SLSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKD---PSSNLS 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 223 TLTTHRKIHTGEKPYKCEECGKA------------FKQSSNLTTHKIIHTGEKPYK---------------CKKCGKAFN 275
Cdd:COG5048   186 LLISSNVSTSIPSSSENSPLSSSysipssssdqnlENSSSSLPLTTNSQLSPKSLLsqspsslsssdssssASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 276 QSAHLTTHEVIHTGE-------KPYKCEKCGKAFNHFSHLTTHK--IIHTGE--KPYKCKE--CGKAFKHSSTLTKHKII 342
Cdd:COG5048   266 PTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 343 HTGEKPYKCKECEKAFNQSSKLTE-------HKKIHTGEKPYECE--KCGKAFNQSSNLTRHKKSHTEEKPYKCeecgkg 413
Cdd:COG5048   346 HTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNC------ 419

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462567384 414 fkwpstltihkiihtgekpyKCEECGKAFNQSSKLTKHKKIHTGEKPYTCEECGKAFNQSS 474
Cdd:COG5048   420 --------------------KNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLD 460
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
235-398 1.35e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.93  E-value: 1.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 235 KPYKCEECGKAFKQSSNLTTHK--IIHTGE--KPYKCKK--CGKAFNQSAHLTTHEVIHTGEKPYKC--EKCGKAFNHFS 306
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLL 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 307 ----HLTTHKIIHTGEKPYKC---KECGKAFKHSSTLTKHKIIHTGEKP--YKCKECEKAFNQSSKLTEHKKIHTGEKPY 377
Cdd:COG5048   368 nnepPQSLQQYKDLKNDKKSEtlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPL 447

                         170       180
                  ....*....|....*....|.
gi 2462567384 378 ECEKCGKaFNQSSNLTRHKKS 398
Cdd:COG5048   448 LCSILKS-FRRDLDLSNHGKD 467
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 149-229 2.45e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.55  E-value: 2.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 149 GEKPYKCE--ECGKAFnQSSNLIKHKKIHTGEKPYKCEECGKTfnrfstltTHKIIHTGEKPYKCKECGKAFNRSSTLTT 226
Cdd:COG5189   346 DGKPYKCPveGCNKKY-KNQNGLKYHMLHGHQNQKLHENPSPE--------KMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ...
gi 2462567384 227 HRK 229
Cdd:COG5189   417 HRK 419
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 429-508 2.79e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.17  E-value: 2.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 429 GEKPYKCE--ECGKAFNQSSKLTKHKKiHTGEKPYTCEecgkafnqSSNLTKHKRIHTGEKPYKCEECDKAFKWSSVLTK 506
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYHML-HGHQNQKLHE--------NPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ..
gi 2462567384 507 HK 508
Cdd:COG5189   417 HR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 280-400 3.69e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.78  E-value: 3.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 280 LTTHEVIHTGEKPYKCEKCGKAFNHFSHLT----THKIIHTGEKPYKCK--ECGKAFKHSSTLTKHKiihtgekpyKCKE 353
Cdd:COG5189   305 ISTGEMIDVRKLPCTNSSSNGKLAHGGERNidtpSRMLKVKDGKPYKCPveGCNKKYKNQNGLKYHM---------LHGH 375

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2462567384 354 CEKAFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSSNLTRHKKSHT 400
Cdd:COG5189   376 QNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYHRKHSH 422
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 373-453 4.03e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.78  E-value: 4.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 373 GEKPYECE--KCGKAFNQSSNLTRHKKsHTEEKPYKCEEcgkgfkwPSTLTiHKIIHTGEKPYKCEECGKAFNQSSKLTK 450
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYHML-HGHQNQKLHEN-------PSPEK-MNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ...
gi 2462567384 451 HKK 453
Cdd:COG5189   417 HRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
475-499 4.75e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 4.75e-04
                          10        20
                  ....*....|....*....|....*
gi 2462567384 475 NLTKHKRIHTGEKPYKCEECDKAFK 499
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
140-164 1.07e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.07e-03
                          10        20
                  ....*....|....*....|....*
gi 2462567384 140 LTKHKRIHTGEKPYKCEECGKAFNQ 164
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
167-192 1.16e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.16e-03
                          10        20
                  ....*....|....*....|....*.
gi 2462567384 167 NLIKHKKIHTGEKPYKCEECGKTFNR 192
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
307-332 1.84e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.84e-03
                          10        20
                  ....*....|....*....|....*.
gi 2462567384 307 HLTTHKIIHTGEKPYKCKECGKAFKH 332
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 177-256 1.96e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.47  E-value: 1.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462567384 177 GEKPYKCE--ECGKTFNRFSTLTTHKiihtgekpyKCKECGKAFNRSSTLTTHRKIHTGEKPYKCEECGKAFKQSSNLTT 254
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ..
gi 2462567384 255 HK 256
Cdd:COG5189   417 HR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
251-276 3.10e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.10e-03
                          10        20
                  ....*....|....*....|....*.
gi 2462567384 251 NLTTHKIIHTGEKPYKCKKCGKAFNQ 276
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
224-248 3.29e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.29e-03
                          10        20
                  ....*....|....*....|....*
gi 2462567384 224 LTTHRKIHTGEKPYKCEECGKAFKQ 248
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
391-415 3.49e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.49e-03
                          10        20
                  ....*....|....*....|....*
gi 2462567384 391 NLTRHKKSHTEEKPYKCEECGKGFK 415
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
448-472 3.81e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.81e-03
                          10        20
                  ....*....|....*....|....*
gi 2462567384 448 LTKHKKIHTGEKPYTCEECGKAFNQ 472
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
364-388 4.29e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 4.29e-03
                          10        20
                  ....*....|....*....|....*
gi 2462567384 364 LTEHKKIHTGEKPYECEKCGKAFNQ 388
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
196-220 5.48e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 5.48e-03
                          10        20
                  ....*....|....*....|....*
gi 2462567384 196 LTTHKIIHTGEKPYKCKECGKAFNR 220
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
336-360 5.93e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 5.93e-03
                          10        20
                  ....*....|....*....|....*
gi 2462567384 336 LTKHKIIHTGEKPYKCKECEKAFNQ 360
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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