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Conserved domains on  [gi|2217334288|ref|XP_047295811|]
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centrosome-associated protein CEP250 isoform X3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
39-213 5.94e-47

Ciliary rootlet component, centrosome cohesion;


:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 167.52  E-value: 5.94e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288   39 WRKLKNSQEAQQRQATLVRKLQAKVLQYRSWCQELEKRLEA---------------TGGPIPQRWENVEEPNLDELLVRL 103
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEktselektelllrklTLEPRLQRLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  104 EEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWRE 183
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 2217334288  184 VVTFRRHFLEMKSATDRDLMELKAEHVRLS 213
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 790-1552 4.16e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 114.77  E-value: 4.16e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  790 LEVQIQTVTQAKEvIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLR-EKWEKERSw 868
Cdd:TIGR02168  205 LERQAEKAERYKE-LKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlEVSELEEE- 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  869 hQQELAKALESLEREKMELEMRLKEQQTEMEaiQAQREEERTQAESALCQMQLETEKERVSLLETLL-QTQKELADASQQ 947
Cdd:TIGR02168  283 -IEELQKELYALANEISRLEQQKQILRERLA--NLERQLEELEAQLEELESKLDELAEELAELEEKLeELKEELESLEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  948 LERLRQDMKVQKLKEQEttgilqtqLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQ- 1026
Cdd:TIGR02168  360 LEELEAELEELESRLEE--------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLe 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1027 ----RLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 1102
Cdd:TIGR02168  432 eaelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAL 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1103 ME----------LLRQEVKEKEADFLAQEAQLLEELEA-----SHITEQQLRASLWAQEAKAAQLQLRLRS----TESQL 1163
Cdd:TIGR02168  512 LKnqsglsgilgVLSELISVDEGYEAAIEAALGGRLQAvvvenLNAAKKAIAFLKQNELGRVTFLPLDSIKgteiQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1164 EALAAEQQPGNQAQAQAQLASLYS-ALQQALGSV-----CESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALS 1237
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRkALSYLLGGVlvvddLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1238 AEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELME 1317
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1318 LHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAagiLEEDLRTARSALKLKNEEVES 1397
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLES 828

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1398 ERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQE 1477
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES 908

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1478 QIQELEKCRSVLEHLPMAVQEREQKLTVQREQIreLEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL 1552
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 429-1052 2.86e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.40  E-value: 2.86e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  429 EGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKE 508
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  509 EQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLK 588
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  589 TEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQL 668
Cdd:COG1196    386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  669 QKAEEAGAELQADLRDIQEEKEEIQKKLS-----ESRHQQEAATTQLEQLHQEAKRQEEVLA--RAVQEKEALVREKAAL 741
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAEAAARLLllleaEADYEGFLEGVKAALLLAGLRGLAGAVAvlIGVEAAYEAALEAALA 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  742 EVRLQAVERDRQDLAEQLQGLSSAKEllesSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQ 821
Cdd:COG1196    546 AALQNIVVEDDEVAAAAIEYLKAAKA----GRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  822 AEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAI 901
Cdd:COG1196    622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  902 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQEttgiLQTQLQEAQRELK 981
Cdd:COG1196    702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE----LERELERLEREIE 777

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217334288  982 E------AArqhRDDLAALQEESSSLLQDKMDLQKQVEDLKsQLVAQddsqrlVEQEVQEKLRETqeYNRIQKELER 1052
Cdd:COG1196    778 AlgpvnlLA---IEEYEELEERYDFLSEQREDLEEARETLE-EAIEE------IDRETRERFLET--FDAVNENFQE 842
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1259-2019 1.34e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 1.34e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1259 RDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRME 1338
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1339 AQGERELLQAAKENLTAQVEHLQaavvearaqaSAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKA 1418
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELE----------SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1419 LQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQ--EQIQELEKCRSVLEHLPMAV 1496
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkELQAELEELEEELEELQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1497 QEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLI 1576
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1577 KELEGQRETQRVALTHLTLDLEERSQELQAQSsqihdlESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERR 1656
Cdd:TIGR02168  537 AAIEAALGGRLQAVVVENLNAAKKAIAFLKQN------ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1657 DQELMLqkeriqVLED--QRTRQTKILEEDLEQIKlSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLIlRDK 1734
Cdd:TIGR02168  611 DPKLRK------ALSYllGGVLVVDDLDNALELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-EEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1735 EKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1814
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1815 R---DQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGD 1891
Cdd:TIGR02168  763 IeelEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1892 LRAESREQEKALLALQQQ---CAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQE 1968
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEieeLEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1969 ALGKAHAALQGKEQHLLEQAELSRSL--------EASTATLQASLDACQAHSRQLEEAL 2019
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKI 981
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1746-2313 3.34e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 3.34e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1746 HELQELKDQLEQQLQGLHRKVGETSL-LLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQ 1824
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELeELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1825 EQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALL 1904
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1905 ALQQQCAEQAQEHEVETRALQDSwLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHL 1984
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAEL-AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1985 LEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKS 2064
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2065 LAQRVQENmiqEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSL 2144
Cdd:COG1196    535 AYEAALEA---ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2145 EPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEK 2224
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2225 ERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEpspdgMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVE 2304
Cdd:COG1196    692 ELELEEALLAEEEEERELAEAEEERLEEELEEE-----ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766


                   ....*....
gi 2217334288 2305 RERRKLKRE 2313
Cdd:COG1196    767 RELERLERE 775
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 246-491 1.70e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 1.70e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  246 LLLLLAKTQELEKEAHERSQELIQLKSQgdleKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELME 325
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQE----IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  326 HEASLSRNAQEEKLSLQQVIKDITQVMVEegdniAQGSGHENSLELdssIFSQFDYQDADKALTLVRSVLTRRRQAVQDL 405
Cdd:COG4942     84 ELAELEKEIAELRAELEAQKEELAELLRA-----LYRLGRQPPLAL---LLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  406 RQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQE 485
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235


                   ....*.
gi 2217334288  486 AWRLRR 491
Cdd:COG4942    236 AAAAAE 241
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
39-213 5.94e-47

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 167.52  E-value: 5.94e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288   39 WRKLKNSQEAQQRQATLVRKLQAKVLQYRSWCQELEKRLEA---------------TGGPIPQRWENVEEPNLDELLVRL 103
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEktselektelllrklTLEPRLQRLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  104 EEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWRE 183
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 2217334288  184 VVTFRRHFLEMKSATDRDLMELKAEHVRLS 213
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 790-1552 4.16e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 114.77  E-value: 4.16e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  790 LEVQIQTVTQAKEvIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLR-EKWEKERSw 868
Cdd:TIGR02168  205 LERQAEKAERYKE-LKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlEVSELEEE- 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  869 hQQELAKALESLEREKMELEMRLKEQQTEMEaiQAQREEERTQAESALCQMQLETEKERVSLLETLL-QTQKELADASQQ 947
Cdd:TIGR02168  283 -IEELQKELYALANEISRLEQQKQILRERLA--NLERQLEELEAQLEELESKLDELAEELAELEEKLeELKEELESLEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  948 LERLRQDMKVQKLKEQEttgilqtqLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQ- 1026
Cdd:TIGR02168  360 LEELEAELEELESRLEE--------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLe 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1027 ----RLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 1102
Cdd:TIGR02168  432 eaelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAL 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1103 ME----------LLRQEVKEKEADFLAQEAQLLEELEA-----SHITEQQLRASLWAQEAKAAQLQLRLRS----TESQL 1163
Cdd:TIGR02168  512 LKnqsglsgilgVLSELISVDEGYEAAIEAALGGRLQAvvvenLNAAKKAIAFLKQNELGRVTFLPLDSIKgteiQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1164 EALAAEQQPGNQAQAQAQLASLYS-ALQQALGSV-----CESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALS 1237
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRkALSYLLGGVlvvddLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1238 AEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELME 1317
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1318 LHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAagiLEEDLRTARSALKLKNEEVES 1397
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLES 828

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1398 ERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQE 1477
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES 908

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1478 QIQELEKCRSVLEHLPMAVQEREQKLTVQREQIreLEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL 1552
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 429-1052 2.86e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.40  E-value: 2.86e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  429 EGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKE 508
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  509 EQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLK 588
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  589 TEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQL 668
Cdd:COG1196    386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  669 QKAEEAGAELQADLRDIQEEKEEIQKKLS-----ESRHQQEAATTQLEQLHQEAKRQEEVLA--RAVQEKEALVREKAAL 741
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAEAAARLLllleaEADYEGFLEGVKAALLLAGLRGLAGAVAvlIGVEAAYEAALEAALA 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  742 EVRLQAVERDRQDLAEQLQGLSSAKEllesSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQ 821
Cdd:COG1196    546 AALQNIVVEDDEVAAAAIEYLKAAKA----GRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  822 AEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAI 901
Cdd:COG1196    622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  902 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQEttgiLQTQLQEAQRELK 981
Cdd:COG1196    702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE----LERELERLEREIE 777

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217334288  982 E------AArqhRDDLAALQEESSSLLQDKMDLQKQVEDLKsQLVAQddsqrlVEQEVQEKLRETqeYNRIQKELER 1052
Cdd:COG1196    778 AlgpvnlLA---IEEYEELEERYDFLSEQREDLEEARETLE-EAIEE------IDRETRERFLET--FDAVNENFQE 842
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 863-1449 1.80e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 102.71  E-value: 1.80e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  863 EKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAEsalcqmqlETEKERVSLLETLLQTQKELA 942
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE--------ELRLELEELELELEEAQAEEY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  943 DASQQLERLRQDMKVQKLKEQettgilqtQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQ 1022
Cdd:COG1196    292 ELLAELARLEQDIARLEERRR--------ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1023 DDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 1102
Cdd:COG1196    364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1103 MELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQL 1182
Cdd:COG1196    444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1183 ASLysALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRgplltALSAEAVASALHKLHQDLWKTQQTRDVL 1262
Cdd:COG1196    524 GAV--AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA-----AKAGRATFLPLDKIRARAALAAALARGA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1263 RDQVQKLEERLTDTEAEKSQVHtELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGE 1342
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVL-GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1343 RELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQEN 1422
Cdd:COG1196    676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

                          570       580
                   ....*....|....*....|....*..
gi 2217334288 1423 LALLtQTLAEREEEVETLRGQIQELEK 1449
Cdd:COG1196    756 LPEP-PDLEELERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1259-2019 1.34e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 1.34e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1259 RDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRME 1338
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1339 AQGERELLQAAKENLTAQVEHLQaavvearaqaSAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKA 1418
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELE----------SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1419 LQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQ--EQIQELEKCRSVLEHLPMAV 1496
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkELQAELEELEEELEELQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1497 QEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLI 1576
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1577 KELEGQRETQRVALTHLTLDLEERSQELQAQSsqihdlESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERR 1656
Cdd:TIGR02168  537 AAIEAALGGRLQAVVVENLNAAKKAIAFLKQN------ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1657 DQELMLqkeriqVLED--QRTRQTKILEEDLEQIKlSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLIlRDK 1734
Cdd:TIGR02168  611 DPKLRK------ALSYllGGVLVVDDLDNALELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-EEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1735 EKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1814
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1815 R---DQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGD 1891
Cdd:TIGR02168  763 IeelEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1892 LRAESREQEKALLALQQQ---CAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQE 1968
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEieeLEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1969 ALGKAHAALQGKEQHLLEQAELSRSL--------EASTATLQASLDACQAHSRQLEEAL 2019
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1589-2155 5.23e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.70  E-value: 5.23e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1589 ALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQ 1668
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1669 VLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHEL 1748
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1749 QELKdQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQ 1828
Cdd:COG1196    393 RAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1829 AQGQEERVKEKADALQGALEQAHMTLKERhgELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQ 1908
Cdd:COG1196    472 AALLEAALAELLEELAEAAARLLLLLEAE--ADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1909 QCAEQAQehevetralqdswlQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQA 1988
Cdd:COG1196    550 NIVVEDD--------------EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARY 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1989 ELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDV-QQLQQALAQRDEELRHQQEREQLLEKSLAQ 2067
Cdd:COG1196    616 YVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGgSRRELLAALLEAEAELEELAERLAEEELEL 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2068 RVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDslepR 2147
Cdd:COG1196    696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE----R 771


                   ....*...
gi 2217334288 2148 LQRELERL 2155
Cdd:COG1196    772 LEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 456-1114 2.20e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 92.90  E-value: 2.20e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  456 GEVDSLSKERELLQKArEELRQQLEVLEQEAWRlrrvnvelqlQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQ 535
Cdd:PTZ00121  1109 GKAEEARKAEEAKKKA-EDARKAEEARKAEDAR----------KAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKK 1177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  536 SESLSELITLREALESSHLEgELLRQEQtevtAALARAEQSIAELSSSENTLKTEvADLRAAAVKLSAlNEALALDKVGL 615
Cdd:PTZ00121  1178 AEAARKAEEVRKAEELRKAE-DARKAEA----ARKAEEERKAEEARKAEDAKKAE-AVKKAEEAKKDA-EEAKKAEEERN 1250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  616 NQQLLQLEEENQSVCSRMEA---AEQARNALQVDLAEAEKRREAL--WEKNTHLEAQLQKAEEA--GAELQADLRDIQEE 688
Cdd:PTZ00121  1251 NEEIRKFEEARMAHFARRQAaikAEEARKADELKKAEEKKKADEAkkAEEKKKADEAKKKAEEAkkADEAKKKAEEAKKK 1330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  689 KEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEV-----LARAVQEKEALVREKAALEVR----LQAVERDRQDLAEQL 759
Cdd:PTZ00121  1331 ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKaeaaeKKKEEAKKKADAAKKKAEEKKkadeAKKKAEEDKKKADEL 1410

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  760 QGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQI--QTVTQAKEVIQGEVRCLKLE----LDTERSQAEQERDA----- 828
Cdd:PTZ00121  1411 KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKadEAKKKAEEAKKAEEAKKKAEeakkADEAKKKAEEAKKAdeakk 1490

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  829 -------AARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSwhqQELAKALESLEREKMELEMRLKEQQTEMEAI 901
Cdd:PTZ00121  1491 kaeeakkKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA---DEAKKAEEKKKADELKKAEELKKAEEKKKAE 1567

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  902 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELaDASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELK 981
Cdd:PTZ00121  1568 EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKM-KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK 1646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  982 EAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLK----------SQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELE 1051
Cdd:PTZ00121  1647 KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKkaeedekkaaEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEE 1726

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217334288 1052 REKASLTLSLMEKEQRLLVLQEAdSIRQQELSALRQDMQEAQGEQKELSAQME-LLRQEVKEKE 1114
Cdd:PTZ00121  1727 ENKIKAEEAKKEAEEDKKKAEEA-KKDEEEKKKIAHLKKEEEKKAEEIRKEKEaVIEEELDEED 1789
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 241-951 5.77e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 5.77e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  241 REPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNH 320
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  321 TELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFsqfdyQDADKALTLVRSVLTRRRQ 400
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL-----EELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  401 AVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLtgERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLE 480
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  481 VLEQEAWRLRRVNVELQLQGDSaQGQKEEQQEELHLAVRERERLQEMLMGLEAkqseSLSELITLREALES--------- 551
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILG----VLSELISVDEGYEAaieaalggr 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  552 --------------------------------SHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAV 599
Cdd:TIGR02168  547 lqavvvenlnaakkaiaflkqnelgrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  600 KLSALNEALALDK-VGLNQQLLQLEEENQSVCSRM----EAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEA 674
Cdd:TIGR02168  627 VVDDLDNALELAKkLRPGYRIVTLDGDLVRPGGVItggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  675 GAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQD 754
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  755 LAEQLQGLSSAKELLESSLFEAQQQnsvievtKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLA 834
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAE-------LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  835 QAE--QEGKTALEQQKAAHEKEVNQLREKWEKERSwHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA 912
Cdd:TIGR02168  860 EIEelEELIEELESELEALLNERASLEEALALLRS-ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*.
gi 2217334288  913 E------SALCQMQLETEKERVSLLETLLQ-TQKELADASQQLERL 951
Cdd:TIGR02168  939 DnlqerlSEEYSLTLEEAEALENKIEDDEEeARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1746-2313 3.34e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 3.34e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1746 HELQELKDQLEQQLQGLHRKVGETSL-LLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQ 1824
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELeELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1825 EQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALL 1904
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1905 ALQQQCAEQAQEHEVETRALQDSwLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHL 1984
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAEL-AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1985 LEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKS 2064
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2065 LAQRVQENmiqEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSL 2144
Cdd:COG1196    535 AYEAALEA---ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2145 EPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEK 2224
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2225 ERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEpspdgMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVE 2304
Cdd:COG1196    692 ELELEEALLAEEEEERELAEAEEERLEEELEEE-----ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766


                   ....*....
gi 2217334288 2305 RERRKLKRE 2313
Cdd:COG1196    767 RELERLERE 775
PTZ00121 PTZ00121
MAEBL; Provisional
 636-1490 1.75e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.64  E-value: 1.75e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  636 AEQARNALQVDLAEAEKRREALweknthleaqlQKAEEAgaelqadlRDIQE-EKEEIQKKLSESRHQQEAATTQLEQLH 714
Cdd:PTZ00121  1100 AEEAKKTETGKAEEARKAEEAK-----------KKAEDA--------RKAEEaRKAEDARKAEEARKAEDAKRVEIARKA 1160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  715 QEAKRQEEvlARAVQEKEALVREKAALEVRlqaverdrqdLAEQLQGLSSAKELLESSLFEAQQQnsVIEVTKGQLEVQI 794
Cdd:PTZ00121  1161 EDARKAEE--ARKAEDAKKAEAARKAEEVR----------KAEELRKAEDARKAEAARKAEEERK--AEEARKAEDAKKA 1226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  795 QTVTQAKEVIQGEVRCLKLE---LDTERSQAEQERDA--AARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSwh 869
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEeerNNEEIRKFEEARMAhfARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA-- 1304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  870 qQELAKALESlEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSlletllQTQKELADASQQLE 949
Cdd:PTZ00121  1305 -DEAKKKAEE-AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA------EEKAEAAEKKKEEA 1376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  950 RLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARqhrddlAALQEESSSLLQDKMDLQKQVEDLKSQLvaqddSQRLV 1029
Cdd:PTZ00121  1377 KKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKK------AAAAKKKADEAKKKAEEKKKADEAKKKA-----EEAKK 1445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1030 EQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRllvlqEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQE 1109
Cdd:PTZ00121  1446 ADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK-----KADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE 1520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1110 VKEKEADFLAQEAQLLEELEASHITEQqlraslwAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSAL 1189
Cdd:PTZ00121  1521 AKKADEAKKAEEAKKADEAKKAEEKKK-------ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1190 QQALGSVCESRPELSGGGDSAPSVWGLEPDQ-NGARSLFKRGPLLTALSAEAVASAlhklhQDLWKTQQTRDVLRDQVQK 1268
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKA-----EELKKAEEENKIKAAEEAK 1668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1269 LEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERellQA 1348
Cdd:PTZ00121  1669 KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDK---KK 1745

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1349 AKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKAlQENLALLTQ 1428
Cdd:PTZ00121  1746 AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGK-EGNLVINDS 1824

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217334288 1429 TLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLE 1490
Cdd:PTZ00121  1825 KEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEE 1886
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 809-1672 3.14e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 69.23  E-value: 3.14e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  809 RCLKLELDTERSQAEQERDAAaRQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELE 888
Cdd:pfam02463  190 IDLEELKLQELKLKEQAKKAL-EYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  889 MRLKEQQTEMEAIQAQREEertqaesalcQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGI 968
Cdd:pfam02463  269 QVLKENKEEEKEKKLQEEE----------LKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  969 LQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQ-VEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQ 1047
Cdd:pfam02463  339 ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLeSERLSSAAKLKEEELELKSEEEKEAQLLLELARQLE 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1048 KELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQmELLRQEVKEKEADFLAQEAQLLEE 1127
Cdd:pfam02463  419 DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL-LKETQLVKLQEQLELLLSRQKLEE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1128 LEAShitEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGG 1207
Cdd:pfam02463  498 RSQK---ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELP 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1208 DSAPSVWGLEPDQNGARSLFKRGPLLTALSA----EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQV 1283
Cdd:pfam02463  575 LGARKLRLLIPKLKLPLKSIAVLEIDPILNLaqldKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1284 HTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAA 1363
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1364 VVEARAQASAAGILEEDLrTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQ 1443
Cdd:pfam02463  735 NEELKLLKQKIDEEEEEE-EKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEE 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1444 IQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKcrsvLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNV 1523
Cdd:pfam02463  814 AELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE----ELERLEEEITKEELLQELLLKEEELEEQKLKDELE 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1524 LEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALEleenhHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQE 1603
Cdd:pfam02463  890 SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEA-----EILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1604 LQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLED 1672
Cdd:pfam02463  965 LLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGW 1033
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1380-1899 5.67e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.06  E-value: 5.67e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1380 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALL-------TQTLAEREEEVETLRGQIQELEKQRE 1452
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLeaeiedlRETIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1453 MQKAALELLSLDLKKRNQEVDLQQEQIQELEK----CRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQL 1528
Cdd:PRK02224   290 ELEEERDDLLAEAGLDDADAEAVEARREELEDrdeeLRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1529 LELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKE----LEGQRETQRVALTHLTLDLEERSQEL 1604
Cdd:PRK02224   370 SELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREerdeLREREAELEATLRTARERVEEAEALL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1605 QAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQ------ELMLQKERIQVLEDQRTRQT 1678
Cdd:PRK02224   450 EAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDlveaedRIERLEERREDLEELIAERR 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1679 KILEEDLEQIKlSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVEcQQEHIHELQELKDQLEQQ 1758
Cdd:PRK02224   530 ETIEEKRERAE-ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIRTLLAAIADAEDE 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1759 LQGLHRKVGETSLLLSQReqeivvlQQQLQEAREQ-GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVK 1837
Cdd:PRK02224   608 IERLREKREALAELNDER-------RERLAEKRERkRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQ 680

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217334288 1838 EKADALQGALEQAHmTLKERHGELQDHKEQARRLEEElavegrrVQALEEVLGDLRAESREQ 1899
Cdd:PRK02224   681 AEIGAVENELEELE-ELRERREALENRVEALEALYDE-------AEELESMYGDLRAELRQR 734
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1308-1884 1.38e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 63.98  E-value: 1.38e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1308 QNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTA----QVEHLQAAVVEARAQASAAGILEED-LR 1382
Cdd:pfam15921  266 QDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEDkIE 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1383 TARSALKLKNEEV-ESERERAQALQEQGELkvaqgkalQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELL 1461
Cdd:pfam15921  346 ELEKQLVLANSELtEARTERDQFSQESGNL--------DDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHL 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1462 SLDLKKRNQEVDLQQEQIQELE-KCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEhqllELEKKDQMIES 1540
Cdd:pfam15921  418 RRELDDRNMEVQRLEALLKAMKsECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVE----ELTAKKMTLES 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1541 QRGQVQDLKKQLVTLECLALELEENHHKMECQQKL----IKELEGQRETQRVALTH---LTLDLEERSQELQAQSSQIHD 1613
Cdd:pfam15921  494 SERTVSDLTASLQEKERAIEATNAEITKLRSRVDLklqeLQHLKNEGDHLRNVQTEceaLKLQMAEKDKVIEILRQQIEN 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1614 LES-------HSTVLARELQERDQEVKSQREQIEE---LQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEE 1683
Cdd:pfam15921  574 MTQlvgqhgrTAGAMQVEKAQLEKEINDRRLELQEfkiLKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQ 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1684 DLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLH 1763
Cdd:pfam15921  654 ERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQ 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1764 RKVGETSLLLSQREQEIvvlqQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADAL 1843
Cdd:pfam15921  734 KQITAKRGQIDALQSKI----QFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANM 809

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 2217334288 1844 QGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQA 1884
Cdd:pfam15921  810 EVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 246-491 1.70e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 1.70e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  246 LLLLLAKTQELEKEAHERSQELIQLKSQgdleKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELME 325
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQE----IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  326 HEASLSRNAQEEKLSLQQVIKDITQVMVEegdniAQGSGHENSLELdssIFSQFDYQDADKALTLVRSVLTRRRQAVQDL 405
Cdd:COG4942     84 ELAELEKEIAELRAELEAQKEELAELLRA-----LYRLGRQPPLAL---LLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  406 RQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQE 485
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235


                   ....*.
gi 2217334288  486 AWRLRR 491
Cdd:COG4942    236 AAAAAE 241
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 251-601 9.93e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 9.93e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  251 AKTQELEKEAHERSQELIQLKSQGDL---EKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHE 327
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEEleeELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  328 ASLSRNAQEEKLSLQQVIKDITQVMveegdniAQGSGHENSLELDSSIFSqfdyqDADKALTLVRSVLTRRRQAVQDLRQ 407
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELE-------AQIEQLKEELKALREALD-----ELRAELTLLNEEAANLRERLESLER 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  408 QLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAW 487
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  488 RLRRVNVELQLQ-GDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESshlegelLRQEQTEV 566
Cdd:TIGR02168  912 ELRRELEELREKlAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR-------LENKIKEL 984

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 2217334288  567 TAALARAEQSIAELSSSENTLKTEVADLRAAAVKL 601
Cdd:TIGR02168  985 GPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETL 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 12-580 3.64e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.75  E-value: 3.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288   12 KPQSLQLVLEEQVLALQQQMAENQAASWRKLKNSQEAQQRQATL-VRKLQAKVLQYRSWCQELEKRLEATGGPIPQRWEN 90
Cdd:TIGR02168  350 KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELqIASLNNEIERLEARLERLEDRRERLQQEIEELLKK 429

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288   91 VEEPNLDELLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQMEQEFFKGY- 169
Cdd:TIGR02168  430 LEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVk 509

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  170 --------LKGEHGRLLSL-----------------------------WREVVTF-------RRHFLEMKSATDRDLMEL 205
Cdd:TIGR02168  510 allknqsgLSGILGVLSELisvdegyeaaieaalggrlqavvvenlnaAKKAIAFlkqnelgRVTFLPLDSIKGTEIQGN 589

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  206 KAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDG----REPAQLLLLLAKTQELEK----------------------- 258
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGvlvvDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktn 669

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  259 -EAHERSQELIQLKSQgdleKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEE 337
Cdd:TIGR02168  670 sSILERRREIEELEEK----IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  338 KLSLQQVIKDITQVMVEEgdNIAQGSGHENSLELdssifsqfdyQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVN 417
Cdd:TIGR02168  746 EERIAQLSKELTELEAEI--EELEERLEEAEEEL----------AEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  418 LLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQ 497
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLR 893

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  498 LQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSH-LEGELLRQEQTEVTAALARAEQS 576
Cdd:TIGR02168  894 SELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYsLTLEEAEALENKIEDDEEEARRR 973


                   ....
gi 2217334288  577 IAEL 580
Cdd:TIGR02168  974 LKRL 977
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 418-1120 5.35e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.90  E-value: 5.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  418 LLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQ 497
Cdd:pfam02463  304 KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  498 LQGDSAQGQKEEQQEELHLAVRE-------RERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAAL 570
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEaqlllelARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKD 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  571 ARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEA 650
Cdd:pfam02463  464 ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKV 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  651 EKRRE--ALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQ-EAKRQEEVLARA 727
Cdd:pfam02463  544 AISTAviVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKaTLEADEDDKRAK 623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  728 VQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGE 807
Cdd:pfam02463  624 VVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKK 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  808 VRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQK--AAHEKEVNQLREKWEKERSWHQQELAKALESLEREKM 885
Cdd:pfam02463  704 KEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKidEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKT 783

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  886 ELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQET 965
Cdd:pfam02463  784 EKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEI 863

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  966 TGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEvQEKLRETQEYNR 1045
Cdd:pfam02463  864 TKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEIL-LKYEEEPEELLL 942

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1046 IQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQ 1120
Cdd:pfam02463  943 EEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 648-1040 1.55e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 46.93  E-value: 1.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  648 AEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLrdiqeekEEIQKKLSESRHQQEAA-TTQLEQLHQEAKRQEEVLaR 726
Cdd:NF033838    37 AEEVRGGNNPTVTSSGNESQKEHAKEVESHLEKIL-------SEIQKSLDKRKHTQNVAlNKKLSDIKTEYLYELNVL-K 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  727 AVQEKEALVREKAALEVrlqAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQnsvievtKGQLEVQIQTVTQAK---EV 803
Cdd:NF033838   109 EKSEAELTSKTKKELDA---AFEQFKKDTLEPGKKVAEATKKVEEAEKKAKDQ-------KEEDRRNYPTNTYKTlelEI 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  804 IQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTAleqqKAAHEKEVNQLREKWEKE-RSWHQQELAKALESL-- 880
Cdd:NF033838   179 AESDVEVKKAELELVKEEAKEPRDEEKIKQAKAKVESKKA----EATRLEKIKTDREKAEEEaKRRADAKLKEAVEKNva 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  881 EREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQmqlETekervsLLETLLQTQKELADASQQLERLRQDMKVQKL 960
Cdd:NF033838   255 TSEQDKPKRRAKRGVLGEPATPDKKENDAKSSDSSVGE---ET------LPSPSLKPEKKVAEAEKKVEEAKKKAKDQKE 325

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  961 KEQE-----TTGILQTQLQEAQRELKEA--------ARQHRDD--LAALQEESSSLLQDKMDLQKQVEDLKSqlvAQDDS 1025
Cdd:NF033838   326 EDRRnyptnTYKTLELEIAESDVKVKEAelelvkeeAKEPRNEekIKQAKAKVESKKAEATRLEKIKTDRKK---AEEEA 402

                          410
                   ....*....|....*..
gi 2217334288 1026 QRLVEQE--VQEKLRET 1040
Cdd:NF033838   403 KRKAAEEdkVKEKPAEQ 419
PTZ00121 PTZ00121
MAEBL; Provisional
 1986-2355 5.35e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 5.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1986 EQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALaqRDEELRHQQEREQLlekSL 2065
Cdd:PTZ00121  1082 DAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDAR--KAEEARKAEDAKRV---EI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2066 AQRVQE-NMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEE----QSLK 2140
Cdd:PTZ00121  1157 ARKAEDaRKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAvkkaEEAK 1236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2141 LDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRR 2220
Cdd:PTZ00121  1237 KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2221 ALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTL 2300
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217334288 2301 EQVERERRKLKREAMRAAQA-GSLEISKATASSPTQQDGRGQKNSDAKCVAELQKE 2355
Cdd:PTZ00121  1397 KKKAEEDKKKADELKKAAAAkKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKK 1452
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2047-2324 1.72e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 1.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2047 RDEELRHQQEREQLLE---KSLAQRVQENMIQEKQNLGQ-EREEEEIRGLHQSVRELQLTLAQKEQEILEL-RETQQRNN 2121
Cdd:TIGR02169  207 REKAERYQALLKEKREyegYELLKEKEALERQKEAIERQlASLEEELEKLTEEISELEKRLEEIEQLLEELnKKIKDLGE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2122 LEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAR------EIE-WREKAQDLALSLAQTKASVSSLQEVA 2194
Cdd:TIGR02169  287 EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEidkllaEIEeLEREIEEERKRRDKLTEEYAELKEEL 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2195 MFLQASVLERDSEQQRLQDELELTRRALEK-ERLHSPGATSTAELGSRGEQGVQLG-----EVSGVEAEPSPDGMEKQSW 2268
Cdd:TIGR02169  367 EDLRAELEEVDKEFAETRDELKDYREKLEKlKREINELKRELDRLQEELQRLSEELadlnaAIAGIEAKINELEEEKEDK 446

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217334288 2269 RQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRA-AQAGSLE 2324
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAeAQARASE 503
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
39-213 5.94e-47

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 167.52  E-value: 5.94e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288   39 WRKLKNSQEAQQRQATLVRKLQAKVLQYRSWCQELEKRLEA---------------TGGPIPQRWENVEEPNLDELLVRL 103
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEktselektelllrklTLEPRLQRLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  104 EEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWRE 183
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 2217334288  184 VVTFRRHFLEMKSATDRDLMELKAEHVRLS 213
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 790-1552 4.16e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 114.77  E-value: 4.16e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  790 LEVQIQTVTQAKEvIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLR-EKWEKERSw 868
Cdd:TIGR02168  205 LERQAEKAERYKE-LKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlEVSELEEE- 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  869 hQQELAKALESLEREKMELEMRLKEQQTEMEaiQAQREEERTQAESALCQMQLETEKERVSLLETLL-QTQKELADASQQ 947
Cdd:TIGR02168  283 -IEELQKELYALANEISRLEQQKQILRERLA--NLERQLEELEAQLEELESKLDELAEELAELEEKLeELKEELESLEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  948 LERLRQDMKVQKLKEQEttgilqtqLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQ- 1026
Cdd:TIGR02168  360 LEELEAELEELESRLEE--------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLe 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1027 ----RLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 1102
Cdd:TIGR02168  432 eaelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAL 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1103 ME----------LLRQEVKEKEADFLAQEAQLLEELEA-----SHITEQQLRASLWAQEAKAAQLQLRLRS----TESQL 1163
Cdd:TIGR02168  512 LKnqsglsgilgVLSELISVDEGYEAAIEAALGGRLQAvvvenLNAAKKAIAFLKQNELGRVTFLPLDSIKgteiQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1164 EALAAEQQPGNQAQAQAQLASLYS-ALQQALGSV-----CESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALS 1237
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRkALSYLLGGVlvvddLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1238 AEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELME 1317
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1318 LHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAagiLEEDLRTARSALKLKNEEVES 1397
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLES 828

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1398 ERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQE 1477
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES 908

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1478 QIQELEKCRSVLEHLPMAVQEREQKLTVQREQIreLEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL 1552
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 429-1052 2.86e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.40  E-value: 2.86e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  429 EGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKE 508
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  509 EQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLK 588
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  589 TEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQL 668
Cdd:COG1196    386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  669 QKAEEAGAELQADLRDIQEEKEEIQKKLS-----ESRHQQEAATTQLEQLHQEAKRQEEVLA--RAVQEKEALVREKAAL 741
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAEAAARLLllleaEADYEGFLEGVKAALLLAGLRGLAGAVAvlIGVEAAYEAALEAALA 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  742 EVRLQAVERDRQDLAEQLQGLSSAKEllesSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQ 821
Cdd:COG1196    546 AALQNIVVEDDEVAAAAIEYLKAAKA----GRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  822 AEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAI 901
Cdd:COG1196    622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  902 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQEttgiLQTQLQEAQRELK 981
Cdd:COG1196    702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE----LERELERLEREIE 777

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217334288  982 E------AArqhRDDLAALQEESSSLLQDKMDLQKQVEDLKsQLVAQddsqrlVEQEVQEKLRETqeYNRIQKELER 1052
Cdd:COG1196    778 AlgpvnlLA---IEEYEELEERYDFLSEQREDLEEARETLE-EAIEE------IDRETRERFLET--FDAVNENFQE 842
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 863-1449 1.80e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 102.71  E-value: 1.80e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  863 EKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAEsalcqmqlETEKERVSLLETLLQTQKELA 942
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE--------ELRLELEELELELEEAQAEEY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  943 DASQQLERLRQDMKVQKLKEQettgilqtQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQ 1022
Cdd:COG1196    292 ELLAELARLEQDIARLEERRR--------ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1023 DDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 1102
Cdd:COG1196    364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1103 MELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQL 1182
Cdd:COG1196    444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1183 ASLysALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRgplltALSAEAVASALHKLHQDLWKTQQTRDVL 1262
Cdd:COG1196    524 GAV--AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA-----AKAGRATFLPLDKIRARAALAAALARGA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1263 RDQVQKLEERLTDTEAEKSQVHtELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGE 1342
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVL-GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1343 RELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQEN 1422
Cdd:COG1196    676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

                          570       580
                   ....*....|....*....|....*..
gi 2217334288 1423 LALLtQTLAEREEEVETLRGQIQELEK 1449
Cdd:COG1196    756 LPEP-PDLEELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 382-907 4.35e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 4.35e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  382 QDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSL 461
Cdd:COG1196    263 AELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  462 SKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSE 541
Cdd:COG1196    343 EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  542 LITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQ 621
Cdd:COG1196    423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  622 LEEENQSVCSRMEAAEQARNALQVDlaeaekrrEALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRH 701
Cdd:COG1196    503 YEGFLEGVKAALLLAGLRGLAGAVA--------VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRA 574

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  702 QQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNS 781
Cdd:COG1196    575 TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE 654

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  782 VIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREK 861
Cdd:COG1196    655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 2217334288  862 WEKERswHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREE 907
Cdd:COG1196    735 EELLE--ELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1259-2019 1.34e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 1.34e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1259 RDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRME 1338
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1339 AQGERELLQAAKENLTAQVEHLQaavvearaqaSAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKA 1418
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELE----------SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1419 LQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQ--EQIQELEKCRSVLEHLPMAV 1496
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkELQAELEELEEELEELQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1497 QEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLI 1576
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1577 KELEGQRETQRVALTHLTLDLEERSQELQAQSsqihdlESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERR 1656
Cdd:TIGR02168  537 AAIEAALGGRLQAVVVENLNAAKKAIAFLKQN------ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1657 DQELMLqkeriqVLED--QRTRQTKILEEDLEQIKlSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLIlRDK 1734
Cdd:TIGR02168  611 DPKLRK------ALSYllGGVLVVDDLDNALELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-EEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1735 EKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1814
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1815 R---DQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGD 1891
Cdd:TIGR02168  763 IeelEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1892 LRAESREQEKALLALQQQ---CAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQE 1968
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEieeLEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1969 ALGKAHAALQGKEQHLLEQAELSRSL--------EASTATLQASLDACQAHSRQLEEAL 2019
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1589-2155 5.23e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.70  E-value: 5.23e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1589 ALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQ 1668
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1669 VLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHEL 1748
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1749 QELKdQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQ 1828
Cdd:COG1196    393 RAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1829 AQGQEERVKEKADALQGALEQAHMTLKERhgELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQ 1908
Cdd:COG1196    472 AALLEAALAELLEELAEAAARLLLLLEAE--ADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1909 QCAEQAQehevetralqdswlQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQA 1988
Cdd:COG1196    550 NIVVEDD--------------EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARY 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1989 ELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDV-QQLQQALAQRDEELRHQQEREQLLEKSLAQ 2067
Cdd:COG1196    616 YVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGgSRRELLAALLEAEAELEELAERLAEEELEL 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2068 RVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDslepR 2147
Cdd:COG1196    696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE----R 771


                   ....*...
gi 2217334288 2148 LQRELERL 2155
Cdd:COG1196    772 LEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 381-951 3.67e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.00  E-value: 3.67e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  381 YQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLagqtvdlQGEVDS 460
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL-------EQDIAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  461 LSKERELLQKAREELRQQLEVLEQEAwrlrrvnVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLS 540
Cdd:COG1196    307 LEERRRELEERLEELEEELAELEEEL-------EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  541 ELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLL 620
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  621 QLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALweknthLEAQLQKAEEAGAELQADLRDIQeekEEIQKKLSESR 700
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLL------LEAEADYEGFLEGVKAALLLAGL---RGLAGAVAVLI 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  701 HQQEAATTQLEQLHQEAkRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQN 780
Cdd:COG1196    531 GVEAAYEAALEAALAAA-LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  781 SVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLRE 860
Cdd:COG1196    610 EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  861 KWEKERSwHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKE 940
Cdd:COG1196    690 EEELELE-EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768

                          570
                   ....*....|.
gi 2217334288  941 LADASQQLERL 951
Cdd:COG1196    769 LERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 456-1114 2.20e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 92.90  E-value: 2.20e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  456 GEVDSLSKERELLQKArEELRQQLEVLEQEAWRlrrvnvelqlQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQ 535
Cdd:PTZ00121  1109 GKAEEARKAEEAKKKA-EDARKAEEARKAEDAR----------KAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKK 1177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  536 SESLSELITLREALESSHLEgELLRQEQtevtAALARAEQSIAELSSSENTLKTEvADLRAAAVKLSAlNEALALDKVGL 615
Cdd:PTZ00121  1178 AEAARKAEEVRKAEELRKAE-DARKAEA----ARKAEEERKAEEARKAEDAKKAE-AVKKAEEAKKDA-EEAKKAEEERN 1250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  616 NQQLLQLEEENQSVCSRMEA---AEQARNALQVDLAEAEKRREAL--WEKNTHLEAQLQKAEEA--GAELQADLRDIQEE 688
Cdd:PTZ00121  1251 NEEIRKFEEARMAHFARRQAaikAEEARKADELKKAEEKKKADEAkkAEEKKKADEAKKKAEEAkkADEAKKKAEEAKKK 1330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  689 KEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEV-----LARAVQEKEALVREKAALEVR----LQAVERDRQDLAEQL 759
Cdd:PTZ00121  1331 ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKaeaaeKKKEEAKKKADAAKKKAEEKKkadeAKKKAEEDKKKADEL 1410

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  760 QGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQI--QTVTQAKEVIQGEVRCLKLE----LDTERSQAEQERDA----- 828
Cdd:PTZ00121  1411 KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKadEAKKKAEEAKKAEEAKKKAEeakkADEAKKKAEEAKKAdeakk 1490

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  829 -------AARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSwhqQELAKALESLEREKMELEMRLKEQQTEMEAI 901
Cdd:PTZ00121  1491 kaeeakkKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA---DEAKKAEEKKKADELKKAEELKKAEEKKKAE 1567

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  902 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELaDASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELK 981
Cdd:PTZ00121  1568 EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKM-KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK 1646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  982 EAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLK----------SQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELE 1051
Cdd:PTZ00121  1647 KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKkaeedekkaaEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEE 1726

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217334288 1052 REKASLTLSLMEKEQRLLVLQEAdSIRQQELSALRQDMQEAQGEQKELSAQME-LLRQEVKEKE 1114
Cdd:PTZ00121  1727 ENKIKAEEAKKEAEEDKKKAEEA-KKDEEEKKKIAHLKKEEEKKAEEIRKEKEaVIEEELDEED 1789
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 853-1700 5.63e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 5.63e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  853 KEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAEsalcqmqlETEKERVSLLE 932
Cdd:TIGR02168  210 EKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE--------ELRLEVSELEE 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  933 TLLQTQKELADASQQLERLRQDMKVQKLKEQEttgiLQTQLQEAQRELKEAARQH---RDDLAALQEESSSLLQDKMDLQ 1009
Cdd:TIGR02168  282 EIEELQKELYALANEISRLEQQKQILRERLAN----LERQLEELEAQLEELESKLdelAEELAELEEKLEELKEELESLE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1010 KQVEDLKSQLVAQDDSQRLVEQEVQEklretqeYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDM 1089
Cdd:TIGR02168  358 AELEELEAELEELESRLEELEEQLET-------LRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1090 QEAqgEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASlwaqEAKAAQLQLRLRSTESQLEALaae 1169
Cdd:TIGR02168  431 EEA--ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA----ERELAQLQARLDSLERLQENL--- 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1170 QQPGNQAQAQAQLASLYSALQQALGSVCESRPELSgggdsapsvwglepdqngarslfkrgpllTALSAEAVASALHKLH 1249
Cdd:TIGR02168  502 EGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE-----------------------------AAIEAALGGRLQAVVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1250 QDLwktQQTRDVLRDQVQKLEERLTDTEAeKSQVHTELQDLQRQLSQNQEEkskWEGKQNSLESELMELHETMASLQSRL 1329
Cdd:TIGR02168  553 ENL---NAAKKAIAFLKQNELGRVTFLPL-DSIKGTEIQGNDREILKNIEG---FLGVAKDLVKFDPKLRKALSYLLGGV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1330 RRAELQRmEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAG----------ILEEDLRTARSALKLKNEEVESER 1399
Cdd:TIGR02168  626 LVVDDLD-NALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreieELEEKIEELEEKIAELEKALAELR 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1400 ERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQI 1479
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1480 QELEKcrsvlehlpmAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLvtlecla 1559
Cdd:TIGR02168  785 EELEA----------QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI------- 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1560 leleenhhkmECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQI 1639
Cdd:TIGR02168  848 ----------EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRREL 917

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1640 EELQRQKEHLTQDLERRDQELMLQKERI----QVLEDQRTRQTKILEEDLEQIKLSLRERGRELT 1700
Cdd:TIGR02168  918 EELREKLAQLELRLEGLEVRIDNLQERLseeySLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 241-951 5.77e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 5.77e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  241 REPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNH 320
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  321 TELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFsqfdyQDADKALTLVRSVLTRRRQ 400
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL-----EELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  401 AVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLtgERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLE 480
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  481 VLEQEAWRLRRVNVELQLQGDSaQGQKEEQQEELHLAVRERERLQEMLMGLEAkqseSLSELITLREALES--------- 551
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILG----VLSELISVDEGYEAaieaalggr 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  552 --------------------------------SHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAV 599
Cdd:TIGR02168  547 lqavvvenlnaakkaiaflkqnelgrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  600 KLSALNEALALDK-VGLNQQLLQLEEENQSVCSRM----EAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEA 674
Cdd:TIGR02168  627 VVDDLDNALELAKkLRPGYRIVTLDGDLVRPGGVItggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  675 GAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQD 754
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  755 LAEQLQGLSSAKELLESSLFEAQQQnsvievtKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLA 834
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAE-------LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  835 QAE--QEGKTALEQQKAAHEKEVNQLREKWEKERSwHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA 912
Cdd:TIGR02168  860 EIEelEELIEELESELEALLNERASLEEALALLRS-ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*.
gi 2217334288  913 E------SALCQMQLETEKERVSLLETLLQ-TQKELADASQQLERL 951
Cdd:TIGR02168  939 DnlqerlSEEYSLTLEEAEALENKIEDDEEeARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 436-1129 7.19e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.89  E-value: 7.19e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  436 RLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELH 515
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  516 LAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLR 595
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  596 AAAVKLSALNEALALDKVGLNQQLLQLEEENQSVcsRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAG 675
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEEL--LKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  676 AELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEAL-VREK------AALEVRLQAV 748
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIsVDEGyeaaieAALGGRLQAV 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  749 ERDRQDLAEQLQG----------------LSSAKELLESSLFEAQQQNSVIEVTK------------------------- 787
Cdd:TIGR02168  551 VVENLNAAKKAIAflkqnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAKdlvkfdpklrkalsyllggvlvvdd 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  788 --------GQLEVQIQTVTQAKEVIQG---------EVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAA 850
Cdd:TIGR02168  631 ldnalelaKKLRPGYRIVTLDGDLVRPggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEEL 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  851 HEKEVNQLREKWEKERSWHQQElaKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQlETEKERVSL 930
Cdd:TIGR02168  711 EEELEQLRKELEELSRQISALR--KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA-EAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  931 LETLLQTQKELADASQQLERLRQDMkvqklkeqettgilqTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQK 1010
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAEL---------------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1011 QVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQ 1090
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 2217334288 1091 EAQGE----QKELSAQMELLRQEVKEKEADFLAQEAQLLEELE 1129
Cdd:TIGR02168  933 GLEVRidnlQERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 565-1449 1.66e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 1.66e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  565 EVTAALARAEQSIAELSSSENTLKTEVAdlraAAVKLSALNEAL-ALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNAL 643
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLERQAE----KAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  644 QVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEV 723
Cdd:TIGR02168  259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  724 LARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEv 803
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE- 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  804 iqgevrclklELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLERE 883
Cdd:TIGR02168  418 ----------RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  884 KMELEMRLKEQQTEMEAIQAQREEERTQAESA----LCQMQLETEKERVSLLETLLQ------TQKELADASQQLERLRQ 953
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSgilgVLSELISVDEGYEAAIEAALGgrlqavVVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  954 DmKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSsllqdkmDLQKQVEDLKSQLVAQDDSqrlveQEV 1033
Cdd:TIGR02168  568 N-ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDP-------KLRKALSYLLGGVLVVDDL-----DNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1034 QEKLRETQEYNRI---QKELEREKASLT-------LSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQM 1103
Cdd:TIGR02168  635 LELAKKLRPGYRIvtlDGDLVRPGGVITggsaktnSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1104 ELLRQEVKEKEADFLAQEAQLL-EELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQL 1182
Cdd:TIGR02168  715 EQLRKELEELSRQISALRKDLArLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1183 ASLYSALQQALGSVcesRPELSgggdsapsvwglepdqngarslfkrgplLTALSAEAVASALHKLHQDLWKTQQTRDVL 1262
Cdd:TIGR02168  795 KEELKALREALDEL---RAELT----------------------------LLNEEAANLRERLESLERRIAATERRLEDL 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1263 RDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGE 1342
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1343 RELLQAAKENLTAQVEHLQAAVVEaRAQASAAGILEEDLRTARSALKLKnEEVESERERAQALQEQGELKVAQGKALQEN 1422
Cdd:TIGR02168  924 LAQLELRLEGLEVRIDNLQERLSE-EYSLTLEEAEALENKIEDDEEEAR-RRLKRLENKIKELGPVNLAAIEEYEELKER 1001

                          890       900
                   ....*....|....*....|....*..
gi 2217334288 1423 LALLTQTLAEREEEVETLRGQIQELEK 1449
Cdd:TIGR02168 1002 YDFLTAQKEDLTEAKETLEEAIEEIDR 1028
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1400-1972 2.54e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 89.23  E-value: 2.54e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1400 ERAQALQE-----QGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDL 1474
Cdd:COG1196    213 ERYRELKEelkelEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1475 QQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVT 1554
Cdd:COG1196    293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1555 LECLALELEENhhkmecQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKS 1634
Cdd:COG1196    373 ELAEAEEELEE------LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1635 QREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKlslrERGRELTTQRQLMQERAEEGK 1714
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA----DYEGFLEGVKAALLLAGLRGL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1715 GPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQ--EIVVLQQQLQEARE 1792
Cdd:COG1196    523 AGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAalAAALARGAIGAAVD 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1793 QGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERhGELQDHKEQARRLE 1872
Cdd:COG1196    603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR-RELLAALLEAEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1873 EELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSS 1952
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                          570       580
                   ....*....|....*....|
gi 2217334288 1953 RHQEEAARARAEALQEALGK 1972
Cdd:COG1196    762 LEELERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 468-1166 2.62e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 2.62e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  468 LQKAREELRQQLEVLEQE---AWRLRRVNVEL-QLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELI 543
Cdd:TIGR02168  191 LEDILNELERQLKSLERQaekAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  544 TLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLE 623
Cdd:TIGR02168  271 ELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  624 EENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSEsrHQQ 703
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEE--LLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  704 EAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQ-QNSV 782
Cdd:TIGR02168  429 KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGfSEGV 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  783 IEVTKGQLE--------------------------------VQIQTVTQAKEVIQ-----GEVRCLKLELDTERSQAEQE 825
Cdd:TIGR02168  509 KALLKNQSGlsgilgvlselisvdegyeaaieaalggrlqaVVVENLNAAKKAIAflkqnELGRVTFLPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  826 RDAAARQLAQAEQ----------------------------EGKTALEQQKAAHEK----------------------EV 855
Cdd:TIGR02168  589 NDREILKNIEGFLgvakdlvkfdpklrkalsyllggvlvvdDLDNALELAKKLRPGyrivtldgdlvrpggvitggsaKT 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  856 NQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQT-EMEAIQAQREEERTQAESALCQMQLETEKERV-SLLET 933
Cdd:TIGR02168  669 NSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEElEEELEQLRKELEELSRQISALRKDLARLEAEVeQLEER 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  934 LLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQtQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVE 1013
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE-ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1014 DLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQ 1093
Cdd:TIGR02168  828 SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217334288 1094 GEQKELSAQMELLRQ---EVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQ-EAKAAQLQLRLRSTESQLEAL 1166
Cdd:TIGR02168  908 SKRSELRRELEELREklaQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1636-2224 4.49e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 88.46  E-value: 4.49e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1636 REQIEELQRQKEH------LTQDLERRDQELMLQK-ERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQE 1708
Cdd:COG1196    199 ERQLEPLERQAEKaeryreLKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1709 RAEEgkgpSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQ 1788
Cdd:COG1196    279 LELE----LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1789 EAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQA 1868
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1869 RRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAvlkerdQELEALRAE 1948
Cdd:COG1196    435 EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA------EADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1949 SQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGE--I 2026
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARaaL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2027 QDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQK 2106
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2107 EQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKAS 2186
Cdd:COG1196    669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 2217334288 2187 VSSLQEvamflQASVLERDSEQQRLQDELELTRRALEK 2224
Cdd:COG1196    749 EEEALE-----ELPEPPDLEELERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1420-2192 1.91e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 1.91e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1420 QENLALLTQTLAEREEEVETLRGQ----IQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEkcrSVLEHLPMA 1495
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKSLERQaekaERYKELKAELRELELALLVLRLEELREELEELQEELKEAE---EELEELTAE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1496 VQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEEnhhKMECQQKL 1575
Cdd:TIGR02168  262 LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES---KLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1576 IKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLER 1655
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1656 RDQELMLQKERIQVLEDQRTR----QTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLIL 1731
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQaeleELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1732 RDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVG---ETSLLLSQREQEIVV----LQQQLQEAREQGELKEQSLQSQ 1804
Cdd:TIGR02168  499 ENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGyeaAIEAALGGRLQAVVVenlnAAKKAIAFLKQNELGRVTFLPL 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1805 LDEAQRALAQRDQELEALQQEQQQAQGQEERVKEK--------------ADALQGALEQAH-MTLKERHGELQDHKEQAR 1869
Cdd:TIGR02168  579 DSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvVDDLDNALELAKkLRPGYRIVTLDGDLVRPG 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1870 ------RLEEELAVEGRRVQ--ALEEVLGDLRAESREQEKALLALQQQCAEQaqehEVETRALQDSWLQAQAVLKERDQE 1941
Cdd:TIGR02168  659 gvitggSAKTNSSILERRREieELEEKIEELEEKIAELEKALAELRKELEEL----EEELEQLRKELEELSRQISALRKD 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1942 LEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDacqahsrQLEEALRI 2021
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK-------ALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2022 QEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQL 2101
Cdd:TIGR02168  808 LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEE 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2102 TLAQKEQEILELRETQQRNNLEALP----HSHKTSPMEEQSLKLDSLEPRLQRELERLqAALRQTEAREIEwrEKAQDLA 2177
Cdd:TIGR02168  888 ALALLRSELEELSEELRELESKRSElrreLEELREKLAQLELRLEGLEVRIDNLQERL-SEEYSLTLEEAE--ALENKIE 964

                          810
                   ....*....|....*
gi 2217334288 2178 LSLAQTKASVSSLQE 2192
Cdd:TIGR02168  965 DDEEEARRRLKRLEN 979
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1272-1814 2.21e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 2.21e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1272 RLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQG----ERELLQ 1347
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiarLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1348 AAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLT 1427
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1428 QTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQR 1507
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1508 EQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQR 1587
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1588 VALTHLTLDLEERSQELQA------QSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELM 1661
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAgratflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1662 LQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEgkgpskaQRGSLEHMKLILRDKEKEVECQ 1741
Cdd:COG1196    633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE-------LAERLAEEELELEEALLAEEEE 705

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217334288 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1814
Cdd:COG1196    706 ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 245-770 2.89e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.76  E-value: 2.89e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  245 QLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELm 324
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI- 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  325 EHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQD 404
Cdd:COG1196    305 ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  405 LRQQLAGCQEAVNLLQQQHDQwEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQ 484
Cdd:COG1196    385 AEELLEALRAAAELAAQLEEL-EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  485 EAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLR-------EALESSHLEGE 557
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvavligvEAAYEAALEAA 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  558 LLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENqSVCSRMEAAE 637
Cdd:COG1196    544 LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  638 QARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEA 717
Cdd:COG1196    623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2217334288  718 KRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLE 770
Cdd:COG1196    703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 814-1658 6.04e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 84.73  E-value: 6.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  814 ELDTERSQAEQERDAAARQLAQAE---QEGKTALEQQKAAHEK--EVNQLREKWEKERSWhqqELAKALESLEREKMELE 888
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDliiDEKRQQLERLRREREKaeRYQALLKEKREYEGY---ELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  889 MRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQEttgi 968
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELED---- 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  969 LQTQLQEAQRELKEAARQHRDDLAALQEEsssllqdkmdlQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQK 1048
Cdd:TIGR02169  320 AEERLAKLEAEIDKLLAEIEELEREIEEE-----------RKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1049 ELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEadflaqeaQLLEEL 1128
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE--------WKLEQL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1129 EASHITEQQlraSLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLAS--LYSALQQALGSVCE-------- 1198
Cdd:TIGR02169  461 AADLSKYEQ---ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEevLKASIQGVHGTVAQlgsvgery 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1199 -SRPELSGGG----------DSAPSVWGLEPDQNGARSLF--------KRGPLLTALSAEAVASALHKLHQDLWKTQQTR 1259
Cdd:TIGR02169  538 aTAIEVAAGNrlnnvvveddAVAKEAIELLKRRKAGRATFlplnkmrdERRDLSILSEDGVIGFAVDLVEFDPKYEPAFK 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1260 DVLRDQ--VQKLEE-RLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQR 1336
Cdd:TIGR02169  618 YVFGDTlvVEDIEAaRRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1337 MEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQg 1416
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHK- 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1417 kaLQENLALLTQTLAerEEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAV 1496
Cdd:TIGR02169  777 --LEEALNDLEARLS--HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSI 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1497 QEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL-VTLECLALELEENHHKMECQQKL 1575
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELeAQIEKKRKRLSELKAKLEALEEE 932

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1576 IKELEgQRETQRVALTHLTLDLEERSQELQAQSSQIHDLEShstVLARELQERDQEVKSQREQIEELQRQKEHLTQDLER 1655
Cdd:TIGR02169  933 LSEIE-DPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEP---VNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILER 1008


                   ...
gi 2217334288 1656 RDQ 1658
Cdd:TIGR02169 1009 IEE 1011
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 545-1353 8.80e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.34  E-value: 8.80e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  545 LREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEE 624
Cdd:TIGR02168  237 LREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  625 ENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQE 704
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  705 AATTQLEQLHQEAKRQEEVLARAVQEKEALvrEKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIE 784
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQQEIEEL--LKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  785 VTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAAR-----QLAQAEQEGKTALEqqkAAHEKEVNQLR 859
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIlgvlsELISVDEGYEAAIE---AALGGRLQAVV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  860 EKwekerswHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESAL--CQMQLETEKERVSLLETLLQT 937
Cdd:TIGR02168  552 VE-------NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLgvAKDLVKFDPKLRKALSYLLGG 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  938 ---QKELADASQQLERLRQDMKVQKLK-EQETTGILQTQlqeaQRELKEAARQHRddlaalQEESSSLLQDKMDLQKQVE 1013
Cdd:TIGR02168  625 vlvVDDLDNALELAKKLRPGYRIVTLDgDLVRPGGVITG----GSAKTNSSILER------RREIEELEEKIEELEEKIA 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1014 DLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQ 1093
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1094 GEQKELSAQMELLRQEVKEKEADFLAQEAQlLEELEASHiteQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPG 1173
Cdd:TIGR02168  775 EELAEAEAEIEELEAQIEQLKEELKALREA-LDELRAEL---TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1174 NQAQaqaqlaslySALQQALGSVCESRPELSgggdsapsvwglepdqngarslfkrgplltalsaeavaSALHKLHQDLW 1253
Cdd:TIGR02168  851 SEDI---------ESLAAEIEELEELIEELE--------------------------------------SELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1254 KTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRL-RRA 1332
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALeNKI 963

                          810       820
                   ....*....|....*....|.
gi 2217334288 1333 ELQRMEAQGERELLQAAKENL 1353
Cdd:TIGR02168  964 EDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 709-1363 3.07e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 3.07e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  709 QLEQLHQEAKRQEEvlARAVQEKEALVREKAALevrlqaveRDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKG 788
Cdd:COG1196    201 QLEPLERQAEKAER--YRELKEELKELEAELLL--------LKLRELEAELEELEAELEELEAELEELEAELAELEAELE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  789 QLEVQIQTVTQAKEVIQGEVRclklELDTERSQAEQERDAAARQLAQAEQEgktaleqqkaahEKEVNQLREKWEKERSW 868
Cdd:COG1196    271 ELRLELEELELELEEAQAEEY----ELLAELARLEQDIARLEERRRELEER------------LEELEEELAELEEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  869 HQQELAKALESLEREKMELEMRLKEQQtemEAIQAQREEERTQAesalcqmqlETEKERVSLLETLLQTQKELADASQQL 948
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELA---EAEEALLEAEAELA---------EAEEELEELAEELLEALRAAAELAAQL 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  949 ERLRQdmkvqklkEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRL 1028
Cdd:COG1196    403 EELEE--------AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1029 VEQEVQEKLRETQEynRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDmqeAQGEQKELSAQMELLRQ 1108
Cdd:COG1196    475 LEAALAELLEELAE--AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV---EAAYEAALEAALAAALQ 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1109 EVKEKEADFLAQEAQLLEELEASHITEQQLRAslwAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSA 1188
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDK---IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1189 LQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSA--EAVASALHKLHQDLWKTQQTRDVLRDQV 1266
Cdd:COG1196    627 LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEaeAELEELAERLAEEELELEEALLAEEEEE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1267 QKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQR-------MEA 1339
Cdd:COG1196    707 RELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIealgpvnLLA 786

                          650       660
                   ....*....|....*....|....
gi 2217334288 1340 QGERELLQAAKENLTAQVEHLQAA 1363
Cdd:COG1196    787 IEEYEELEERYDFLSEQREDLEEA 810
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1724-2283 7.48e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.14  E-value: 7.48e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1724 LEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQS 1803
Cdd:COG1196    227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1804 QLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQ 1883
Cdd:COG1196    307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1884 ALEEVLGDlRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARA 1963
Cdd:COG1196    387 ELLEALRA-AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1964 EALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQA 2043
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2044 LAQRD---EELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRN 2120
Cdd:COG1196    546 AALQNivvEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2121 NLEALphshktsPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQAS 2200
Cdd:COG1196    626 TLVAA-------RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2201 VLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRgEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVA 2280
Cdd:COG1196    699 LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE-ELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777


                   ...
gi 2217334288 2281 RLE 2283
Cdd:COG1196    778 ALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1746-2313 3.34e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 3.34e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1746 HELQELKDQLEQQLQGLHRKVGETSL-LLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQ 1824
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELeELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1825 EQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALL 1904
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1905 ALQQQCAEQAQEHEVETRALQDSwLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHL 1984
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAEL-AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1985 LEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKS 2064
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2065 LAQRVQENmiqEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSL 2144
Cdd:COG1196    535 AYEAALEA---ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2145 EPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEK 2224
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2225 ERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEpspdgMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVE 2304
Cdd:COG1196    692 ELELEEALLAEEEEERELAEAEEERLEEELEEE-----ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766


                   ....*....
gi 2217334288 2305 RERRKLKRE 2313
Cdd:COG1196    767 RELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 519-896 1.17e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.40  E-value: 1.17e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  519 RERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAA 598
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  599 VKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAEL 678
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  679 QADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAkrqeevlaravqekEALVREKAALEVRLQAVERDRQDLAEQ 758
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL--------------EALLNERASLEEALALLRSELEELSEE 902

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  759 LQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQA----KEVIQGEVRCLKLELDTERSQAEQERDAAARQLA 834
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlseeYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217334288  835 QAEQEGKTALEQQkaaheKEVNQLREKWEKERSwhqqELAKALESLER--EKMELEMRLKEQQT 896
Cdd:TIGR02168  983 ELGPVNLAAIEEY-----EELKERYDFLTAQKE----DLTEAKETLEEaiEEIDREARERFKDT 1037
PTZ00121 PTZ00121
MAEBL; Provisional
 457-1053 2.85e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 76.33  E-value: 2.85e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  457 EVDSLSKERELLQKArEELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHlAVRERERLQEMLMGLEAKQS 536
Cdd:PTZ00121  1303 KADEAKKKAEEAKKA-DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-AAEEKAEAAEKKKEEAKKKA 1380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  537 ESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSalnealaldkvgln 616
Cdd:PTZ00121  1381 DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA-------------- 1446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  617 QQLLQLEEENQSVCSRMEAAEQARNALQVDlAEAEKRREALWEKNTHLEAQlQKAEEAGAELQADLRDIQEEKEEIQKKL 696
Cdd:PTZ00121  1447 DEAKKKAEEAKKAEEAKKKAEEAKKADEAK-KKAEEAKKADEAKKKAEEAK-KKADEAKKAAEAKKKADEAKKAEEAKKA 1524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  697 SESRHQQEAATTQLEQLHQEAKRQEEVLA----RAVQEKEALVREKAALEVRLQAVERdrqdlAEQLQGLSSAKELLESS 772
Cdd:PTZ00121  1525 DEAKKAEEAKKADEAKKAEEKKKADELKKaeelKKAEEKKKAEEAKKAEEDKNMALRK-----AEEAKKAEEARIEEVMK 1599

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  773 LFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHE 852
Cdd:PTZ00121  1600 LYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE 1679

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  853 KEVNQLREKWEKERSWHQQELAKALESLEREKME-----LEMRLKEQQTEMEAIQAQR--EEERTQAESA---------L 916
Cdd:PTZ00121  1680 AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEekkkaEELKKAEEENKIKAEEAKKeaEEDKKKAEEAkkdeeekkkI 1759

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  917 CQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETT----GILQTQLQEAQRELKEAARQHRDDLA 992
Cdd:PTZ00121  1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANiiegGKEGNLVINDSKEMEDSAIKEVADSK 1839

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217334288  993 ALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQK-ELERE 1053
Cdd:PTZ00121  1840 NMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKdDIERE 1901
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 428-1139 3.92e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.49  E-value: 3.92e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  428 EEGKALRQRLQK-----LTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLE----VLEQEAWRLRRVNVELQL 498
Cdd:TIGR02169  211 ERYQALLKEKREyegyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEeieqLLEELNKKIKDLGEEEQL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  499 QGDSAQGQKEEQQEELHLAVRERERLQEmlmGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIA 578
Cdd:TIGR02169  291 RVKEKIGELEAEIASLERSIAEKERELE---DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELE 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  579 ELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALW 658
Cdd:TIGR02169  368 DLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  659 EKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEA---KRQEEVLARAVQEKEALV 735
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVrggRAVEEVLKASIQGVHGTV 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  736 RE--------KAALEV----RLQAVERDRQDLAEQLQGLSSAKEL-----LESSLFEAQQQNSVIEVTKGQLEVQIQTVT 798
Cdd:TIGR02169  528 AQlgsvgeryATAIEVaagnRLNNVVVEDDAVAKEAIELLKRRKAgratfLPLNKMRDERRDLSILSEDGVIGFAVDLVE 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  799 QAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAE---QEGKTALEQQKAAHEKEVNQLREKWEKERSWHQ-QELA 874
Cdd:TIGR02169  608 FDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEGelfEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERlEGLK 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  875 KALESLEREKMELEMRLKEQQTEMEAiqAQREEERTQAESALCQMQLETEKERVSLLETLLQ-TQKELADASQQLERLR- 952
Cdd:TIGR02169  688 RELSSLQSELRRIENRLDELSQELSD--ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSsLEQEIENVKSELKELEa 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  953 --QDMKVQKLKEQETTG-----ILQTQLQEAQRELKEAARQHRDDLAALQE---ESSSLLQDKMDLQKQVEDLKSQLVAQ 1022
Cdd:TIGR02169  766 riEELEEDLHKLEEALNdlearLSHSRIPEIQAELSKLEEEVSRIEARLREieqKLNRLTLEKEYLEKEIQELQEQRIDL 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1023 DDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 1102
Cdd:TIGR02169  846 KEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 2217334288 1103 MELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLR 1139
Cdd:TIGR02169  926 LEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQR 962
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 922-1712 6.11e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.71  E-value: 6.11e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  922 ETEKERVSLLETLLQTQKELADASQQLERL-RQDMKVQKLKEqettgiLQTQLQEAQREL-KEAARQHRDDLAALQEESS 999
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKSLeRQAEKAERYKE------LKAELRELELALlVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1000 SLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQ 1079
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1080 QELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLlEELEASHITEQQLRASLwaqEAKAAQLQLRLRST 1159
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL-EELEEQLETLRSKVAQL---ELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1160 ESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGggdsapsvwglepdqngarslfkrgpllTALSAE 1239
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEE----------------------------LQEELE 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1240 AVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTdteaeksqvhtELQDLQRQLSQNQEEKSKWEGKQNSLESELMELh 1319
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQARLD-----------SLERLQENLEGFSEGVKALLKNQSGLSGILGVL- 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1320 etmaslqsrlrrAELQRMEAQGERELLQAAKENLTA-QVEHLQAAVVEARAQASA----AGILEEDLRTARSALKLKNEE 1394
Cdd:TIGR02168  526 ------------SELISVDEGYEAAIEAALGGRLQAvVVENLNAAKKAIAFLKQNelgrVTFLPLDSIKGTEIQGNDREI 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1395 VESERERAQALQEQGELKVAQGKALQENLA--LLTQTLAE---------REEEVETLRGQIQE----LEKQREMQKAALE 1459
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFDPKLRKALSYLLGgvLVVDDLDNalelakklrPGYRIVTLDGDLVRpggvITGGSAKTNSSIL 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1460 LLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHlpmAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIE 1539
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRK---ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1540 SQRGQVQDLKKQLVTLECLALELEENHHKMEcqqKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHST 1619
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAE---AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1620 VLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRT---RQTKILEEDLEQIKLSLRERG 1696
Cdd:TIGR02168  828 SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAsleEALALLRSELEELSEELRELE 907

                          810
                   ....*....|....*.
gi 2217334288 1697 RELTTQRQLMQERAEE 1712
Cdd:TIGR02168  908 SKRSELRRELEELREK 923
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1783-2319 7.47e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 7.47e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1783 LQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQ 1862
Cdd:COG1196    205 LERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1863 DHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQEL 1942
Cdd:COG1196    285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1943 EALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQ 2022
Cdd:COG1196    365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2023 EGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLT 2102
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2103 LAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQ 2182
Cdd:COG1196    525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2183 TKASVsSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDG 2262
Cdd:COG1196    605 ASDLR-EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE 683

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217334288 2263 MEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRAAQ 2319
Cdd:COG1196    684 LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740
PTZ00121 PTZ00121
MAEBL; Provisional
 636-1490 1.75e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.64  E-value: 1.75e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  636 AEQARNALQVDLAEAEKRREALweknthleaqlQKAEEAgaelqadlRDIQE-EKEEIQKKLSESRHQQEAATTQLEQLH 714
Cdd:PTZ00121  1100 AEEAKKTETGKAEEARKAEEAK-----------KKAEDA--------RKAEEaRKAEDARKAEEARKAEDAKRVEIARKA 1160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  715 QEAKRQEEvlARAVQEKEALVREKAALEVRlqaverdrqdLAEQLQGLSSAKELLESSLFEAQQQnsVIEVTKGQLEVQI 794
Cdd:PTZ00121  1161 EDARKAEE--ARKAEDAKKAEAARKAEEVR----------KAEELRKAEDARKAEAARKAEEERK--AEEARKAEDAKKA 1226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  795 QTVTQAKEVIQGEVRCLKLE---LDTERSQAEQERDA--AARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSwh 869
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEeerNNEEIRKFEEARMAhfARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA-- 1304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  870 qQELAKALESlEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSlletllQTQKELADASQQLE 949
Cdd:PTZ00121  1305 -DEAKKKAEE-AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA------EEKAEAAEKKKEEA 1376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  950 RLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARqhrddlAALQEESSSLLQDKMDLQKQVEDLKSQLvaqddSQRLV 1029
Cdd:PTZ00121  1377 KKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKK------AAAAKKKADEAKKKAEEKKKADEAKKKA-----EEAKK 1445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1030 EQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRllvlqEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQE 1109
Cdd:PTZ00121  1446 ADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK-----KADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE 1520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1110 VKEKEADFLAQEAQLLEELEASHITEQqlraslwAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSAL 1189
Cdd:PTZ00121  1521 AKKADEAKKAEEAKKADEAKKAEEKKK-------ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1190 QQALGSVCESRPELSGGGDSAPSVWGLEPDQ-NGARSLFKRGPLLTALSAEAVASAlhklhQDLWKTQQTRDVLRDQVQK 1268
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKA-----EELKKAEEENKIKAAEEAK 1668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1269 LEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERellQA 1348
Cdd:PTZ00121  1669 KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDK---KK 1745

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1349 AKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKAlQENLALLTQ 1428
Cdd:PTZ00121  1746 AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGK-EGNLVINDS 1824

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217334288 1429 TLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLE 1490
Cdd:PTZ00121  1825 KEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEE 1886
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 244-771 4.97e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 4.97e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  244 AQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTEL 323
Cdd:COG1196    267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  324 MEHEASLsRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGsghensleldssifsQFDYQDADKALTLVRSVLTRRRQAVQ 403
Cdd:COG1196    347 EEAEEEL-EEAEAELAEAEEALLEAEAELAEAEEELEEL---------------AEELLEALRAAAELAAQLEELEEAEE 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  404 DLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLE 483
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  484 QEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQ 563
Cdd:COG1196    491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAK 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  564 TEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNAL 643
Cdd:COG1196    571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  644 QVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEV 723
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*...
gi 2217334288  724 LARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLES 771
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 1030-1797 5.49e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.10  E-value: 5.49e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1030 EQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQE 1109
Cdd:PTZ00121  1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1110 VKEKEADFLAQEAQLLEELEASHITEQQLRASLW--AQEAKAAQLQLRLRSTESQLEALAAEQQPGNqaqaqaqlaslys 1187
Cdd:PTZ00121  1160 AEDARKAEEARKAEDAKKAEAARKAEEVRKAEELrkAEDARKAEAARKAEEERKAEEARKAEDAKKA------------- 1226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1188 alqQALGSVCESRPelsgggdsapsvwglepDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVlrDQVQ 1267
Cdd:PTZ00121  1227 ---EAVKKAEEAKK-----------------DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA--DELK 1284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1268 KLEERLTDTEAEKSQVHTELQDLQRQlsqnQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQ 1347
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKK----AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE 1360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1348 AAKENLTAQvehlQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLT 1427
Cdd:PTZ00121  1361 AAEEKAEAA----EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEA 1436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1428 QTLAEREEEVETLRGQIQELEKQREMQKAALELLSLD-LKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQER----EQK 1502
Cdd:PTZ00121  1437 KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADeAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKkkadEAK 1516

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1503 LTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLikelegq 1582
Cdd:PTZ00121  1517 KAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA------- 1589

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1583 rETQRVALTHLTLDLEERSQELQAQSsqihdlESHSTVLARELQeRDQEVKSQREQIEELQRQKEHLTQDLERRDQELML 1662
Cdd:PTZ00121  1590 -EEARIEEVMKLYEEEKKMKAEEAKK------AEEAKIKAEELK-KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKI 1661

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1663 QKERIQVLEDQRTRQTKIL---EEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEve 1739
Cdd:PTZ00121  1662 KAAEEAKKAEEDKKKAEEAkkaEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA-- 1739

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2217334288 1740 cqQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELK 1797
Cdd:PTZ00121  1740 --EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRME 1795
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
552-1145 7.28e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 71.22  E-value: 7.28e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  552 SHLEGELLRQEQTEVTAALARAEQSIAELSSSentLKTEVADLRAAAVKLSALNEALAlDKVGLNQQLLQLEEENQSVCS 631
Cdd:PRK02224   190 DQLKAQIEEKEEKDLHERLNGLESELAELDEE---IERYEEQREQARETRDEADEVLE-EHEERREELETLEAEIEDLRE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  632 RMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLE 711
Cdd:PRK02224   266 TIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  712 QLHQEAKRQEEvlaravqEKEALVREKAALEVRLQAVERDRQDLAEQLqglssakELLESSLFEAQQQNSVIEVTKGQLE 791
Cdd:PRK02224   346 SLREDADDLEE-------RAEELREEAAELESELEEAREAVEDRREEI-------EELEEEIEELRERFGDAPVDLGNAE 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  792 VQIQTVTQAKEVIQGEVRCLKLELDTERsqaeqERDAAARQLAQAeqeGKTALEQQKAAHEKEVNQLREKWEKerswhQQ 871
Cdd:PRK02224   412 DFLEELREERDELREREAELEATLRTAR-----ERVEEAEALLEA---GKCPECGQPVEGSPHVETIEEDRER-----VE 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  872 ELAKALESLEREKMELEMRLkeqqtemeaiqaQREEERTQAESalcqmQLETEKERVSLLETLLQTQKELADA-SQQLER 950
Cdd:PRK02224   479 ELEAELEDLEEEVEEVEERL------------ERAEDLVEAED-----RIERLEERREDLEELIAERRETIEEkRERAEE 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  951 LRQDMKVQKLKEQETtgilqtqlQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVE 1030
Cdd:PRK02224   542 LRERAAELEAEAEEK--------REAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLRE 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1031 QEVQEKLRETQEYNRIQKELEREK-------ASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQM 1103
Cdd:PRK02224   614 KREALAELNDERRERLAEKRERKReleaefdEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEEL 693

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 2217334288 1104 ELLRQEVKEKEADFLAQEAqLLEELEASHITEQQLRASLWAQ 1145
Cdd:PRK02224   694 EELRERREALENRVEALEA-LYDEAEELESMYGDLRAELRQR 734
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 456-1166 1.74e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.10  E-value: 1.74e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  456 GEVDSLSKERELLQKAREELRQQLEVLEQE---AWRLRRVNVELQ-LQGDSAQGQKEEQQEELHLAVRERERLQEMLMGL 531
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRRErekAERYQALLKEKReYEGYELLKEKEALERQKEAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  532 EAKQSESLSELITLREALESSHLE-GELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALAL 610
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  611 DKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNthleaqlqkaeeagAELQADLRDIQEEKE 690
Cdd:TIGR02169  337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL--------------KDYREKLEKLKREIN 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  691 EIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLE 770
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  771 SSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCL-----KLELDTERSQAEQERDAAAR-------------- 831
Cdd:TIGR02169  483 KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtvaQLGSVGERYATAIEVAAGNRlnnvvveddavake 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  832 --QLAQAEQEGK-TALEQQK-AAHEKEVNQLRE---------------KWEKERSW--------HQQELAKAL------- 877
Cdd:TIGR02169  563 aiELLKRRKAGRaTFLPLNKmRDERRDLSILSEdgvigfavdlvefdpKYEPAFKYvfgdtlvvEDIEAARRLmgkyrmv 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  878 ----ESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLL-QTQKELADASQQLERLR 952
Cdd:TIGR02169  643 tlegELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLdELSQELSDASRKIGEIE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  953 QDMKvQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQ-----DDSQR 1027
Cdd:TIGR02169  723 KEIE-QLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSripeiQAELS 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1028 LVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLR 1107
Cdd:TIGR02169  802 KLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLE 881

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1108 QEVKEKEADFLAQEAQlleeLEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEAL 1166
Cdd:TIGR02169  882 SRLGDLKKERDELEAQ----LRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI 936
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 809-1672 3.14e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 69.23  E-value: 3.14e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  809 RCLKLELDTERSQAEQERDAAaRQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELE 888
Cdd:pfam02463  190 IDLEELKLQELKLKEQAKKAL-EYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  889 MRLKEQQTEMEAIQAQREEertqaesalcQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGI 968
Cdd:pfam02463  269 QVLKENKEEEKEKKLQEEE----------LKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  969 LQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQ-VEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQ 1047
Cdd:pfam02463  339 ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLeSERLSSAAKLKEEELELKSEEEKEAQLLLELARQLE 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1048 KELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQmELLRQEVKEKEADFLAQEAQLLEE 1127
Cdd:pfam02463  419 DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL-LKETQLVKLQEQLELLLSRQKLEE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1128 LEAShitEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGG 1207
Cdd:pfam02463  498 RSQK---ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELP 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1208 DSAPSVWGLEPDQNGARSLFKRGPLLTALSA----EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQV 1283
Cdd:pfam02463  575 LGARKLRLLIPKLKLPLKSIAVLEIDPILNLaqldKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1284 HTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAA 1363
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1364 VVEARAQASAAGILEEDLrTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQ 1443
Cdd:pfam02463  735 NEELKLLKQKIDEEEEEE-EKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEE 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1444 IQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKcrsvLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNV 1523
Cdd:pfam02463  814 AELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE----ELERLEEEITKEELLQELLLKEEELEEQKLKDELE 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1524 LEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALEleenhHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQE 1603
Cdd:pfam02463  890 SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEA-----EILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1604 LQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLED 1672
Cdd:pfam02463  965 LLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGW 1033
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1263-1769 4.90e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 68.53  E-value: 4.90e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1263 RDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRlrraelqRMEAQGE 1342
Cdd:PRK02224   229 REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEE-------RDDLLAE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1343 RELLQAAKENLTAQVEHLQAAVVEaraqasaagiLEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQEN 1422
Cdd:PRK02224   302 AGLDDADAEAVEARREELEDRDEE----------LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1423 LALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSldlkkrnqevdlqqeqiQELEKCRSVLEHLPMAVQEREQK 1502
Cdd:PRK02224   372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE-----------------DFLEELREERDELREREAELEAT 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1503 LTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEgQ 1582
Cdd:PRK02224   435 LRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIE-R 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1583 RETQRVALTHLtldLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQkehlTQDLERRDQELml 1662
Cdd:PRK02224   514 LEERREDLEEL---IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREE----VAELNSKLAEL-- 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1663 qKERIQVLEDQRTRQTKIleEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGpskaqrgslehmklilRDKEKEVECQQ 1742
Cdd:PRK02224   585 -KERIESLERIRTLLAAI--ADAEDEIERLREKREALAELNDERRERLAEKRE----------------RKRELEAEFDE 645

                          490       500
                   ....*....|....*....|....*..
gi 2217334288 1743 EHIHELQELKDQLEQQLQGLHRKVGET 1769
Cdd:PRK02224   646 ARIEEAREDKERAEEYLEQVEEKLDEL 672
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1567-2282 1.08e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.39  E-value: 1.08e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1567 HKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQK 1646
Cdd:TIGR02168  253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1647 EHLTQDLERRDQELMLQKERIQVLEDQRTRqtkiLEEDLEQIKLSLRERGRELTTQRQLMQERAEEGkgpsKAQRGSLEH 1726
Cdd:TIGR02168  333 DELAEELAELEEKLEELKEELESLEAELEE----LEAELEELESRLEELEEQLETLRSKVAQLELQI----ASLNNEIER 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1727 MKLILRDKEKEVECQQEHIHELqeLKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLD 1806
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEEL--LKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1807 EAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD------------------------ALQGALEQAHMTLKERHGELQ 1862
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgilgvlselisvdegyeaaieaALGGRLQAVVVENLNAAKKAI 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1863 DHKEQARrleeelaVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQEL 1942
Cdd:TIGR02168  563 AFLKQNE-------LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1943 EALRAESQSSR--HQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALR 2020
Cdd:TIGR02168  636 ELAKKLRPGYRivTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELE 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2021 IQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQ 2100
Cdd:TIGR02168  716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2101 LTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQ-SLKLDSLEPRLQR------ELERLQAALRQTEAREIEWREKA 2173
Cdd:TIGR02168  796 EELKALREALDELRAELTLLNEEAANLRERLESLERRiAATERRLEDLEEQieelseDIESLAAEIEELEELIEELESEL 875

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2174 QDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAE--LGSRGEQGVQLGEV 2251
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDnlQERLSEEYSLTLEE 955

                          730       740       750
                   ....*....|....*....|....*....|.
gi 2217334288 2252 sgVEAEPSPDGMEKQSWRQRLEHLQQAVARL 2282
Cdd:TIGR02168  956 --AEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 419-772 1.88e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.62  E-value: 1.88e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  419 LQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQL 498
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  499 QGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIA 578
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE 841

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  579 ELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALW 658
Cdd:TIGR02168  842 DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELR 921

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  659 EKNTHLEAQLQKAEEAGAELQADLRDIQE-EKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEkealvre 737
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEE------- 994

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 2217334288  738 kaalevrLQAVERDRQDLAEQLQGLSSAKELLESS 772
Cdd:TIGR02168  995 -------YEELKERYDFLTAQKEDLTEAKETLEEA 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 244-755 2.27e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 2.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  244 AQLLLLLAKTQELEKEAHERSQELIQLKSqgdlEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILEtnhtEL 323
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEE----RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE----AE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  324 MEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSsifsqfdyQDADKALTLVRSVLTRRRQAVQ 403
Cdd:COG1196    360 LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE--------EALLERLERLEEELEELEEALA 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  404 DLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQ----L 479
Cdd:COG1196    432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFlegvK 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  480 EVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELL 559
Cdd:COG1196    512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAA 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  560 RQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEAlaldkVGLNQQLLQLEEENQSVCSRMEAAEQA 639
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA-----VTLAGRLREVTLEGEGGSAGGSLTGGS 666

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  640 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAattQLEQLHQEAKR 719
Cdd:COG1196    667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA---EREELLEELLE 743

                          490       500       510
                   ....*....|....*....|....*....|....*.
gi 2217334288  720 QEEVLARAVQEKEALVREKAALEVRLQAVERDRQDL 755
Cdd:COG1196    744 EEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
632-1169 2.76e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 66.09  E-value: 2.76e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  632 RMEAAEQARNALQvDLAEAEKRREALWEKNTHLEA-----QLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAA 706
Cdd:COG4913    243 ALEDAREQIELLE-PIRELAERYAAARERLAELEYlraalRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDAL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  707 TTQLEQLHQEakrqeeVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQnsvievt 786
Cdd:COG4913    322 REELDELEAQ------IRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE------- 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  787 kgqlevqiqtVTQAKEVIQGEVRclklELDTERSQAEQERDAAARQLAQAEQEgKTALEQQKAAHEKEVNQLREKW---- 862
Cdd:COG4913    389 ----------AAALLEALEEELE----ALEEALAEAEAALRDLRRELRELEAE-IASLERRKSNIPARLLALRDALaeal 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  863 -----------------EKERSWH-----------------QQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEE 908
Cdd:COG4913    454 gldeaelpfvgelievrPEEERWRgaiervlggfaltllvpPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDP 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  909 RTQAEsalcqmQLETEKERVS-LLETLLQTQKELA--DASQQLERLRQDMKVQ-KLKEQETTGILQTQLQEAQREL--KE 982
Cdd:COG4913    534 DSLAG------KLDFKPHPFRaWLEAELGRRFDYVcvDSPEELRRHPRAITRAgQVKGNGTRHEKDDRRRIRSRYVlgFD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  983 AARQhrddLAALQEESSSLLQDKMDLQKQVEDLKSQLvAQDDSQRLVEQEVQEKLRETQEYNRIQKE---LEREKASLTL 1059
Cdd:COG4913    608 NRAK----LAALEAELAELEEELAEAEERLEALEAEL-DALQERREALQRLAEYSWDEIDVASAEREiaeLEAELERLDA 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1060 S---LMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQ 1136
Cdd:COG4913    683 SsddLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDA 762

                          570       580       590
                   ....*....|....*....|....*....|...
gi 2217334288 1137 QLRASLWAQEAKAAQLQLRLRSTESQLEALAAE 1169
Cdd:COG4913    763 VERELRENLEERIDALRARLNRAEEELERAMRA 795
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
534-1068 3.14e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 66.09  E-value: 3.14e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  534 KQSESLSELITLREALESSHLEGELLRQEQTevTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKV 613
Cdd:COG4913    249 EQIELLEPIRELAERYAAARERLAELEYLRA--ALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELD 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  614 GLNQQLLQLEEEnqsvcsRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQ 693
Cdd:COG4913    327 ELEAQIRGNGGD------RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEEL 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  694 KKLSESRHQQEAATTQLEQLHQEAKrqeevlaravQEKEALVREKAALEVRLQAVerdRQDLAEQLqGLSSAK-----EL 768
Cdd:COG4913    401 EALEEALAEAEAALRDLRRELRELE----------AEIASLERRKSNIPARLLAL---RDALAEAL-GLDEAElpfvgEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  769 LESSLFEAQQQNSV------------------------IEVTKGQLEVQIQ---TVTQAKEVIQGEVRCLKLELDTERSQ 821
Cdd:COG4913    467 IEVRPEEERWRGAIervlggfaltllvppehyaaalrwVNRLHLRGRLVYErvrTGLPDPERPRLDPDSLAGKLDFKPHP 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  822 AeqeRDAAARQLAQAEQEGKTALEQQKAAHEK------EVNQLREKWEKERSWHQQEL-------AKALESLEREKMELE 888
Cdd:COG4913    547 F---RAWLEAELGRRFDYVCVDSPEELRRHPRaitragQVKGNGTRHEKDDRRRIRSRyvlgfdnRAKLAALEAELAELE 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  889 MRLKEQQTEMEAIQAQREEERTQAEsaLCQMQLETEKERVSlletLLQTQKELADASQQLERLRQDMkvQKLKEqettgi 968
Cdd:COG4913    624 EELAEAEERLEALEAELDALQERRE--ALQRLAEYSWDEID----VASAEREIAELEAELERLDASS--DDLAA------ 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  969 LQTQLQEAQRELKEAarqhRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRL-VEQEVQEKLRETQE---YN 1044
Cdd:COG4913    690 LEEQLEELEAELEEL----EEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERFAAALGdavER 765

                          570       580
                   ....*....|....*....|....
gi 2217334288 1045 RIQKELEREKASLTLSLMEKEQRL 1068
Cdd:COG4913    766 ELRENLEERIDALRARLNRAEEEL 789
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 382-713 3.86e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 3.86e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  382 QDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSL 461
Cdd:TIGR02168  701 AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  462 SKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSE 541
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  542 LITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQ 621
Cdd:TIGR02168  861 IEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  622 LeeenqsvcsrmeaAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRH 701
Cdd:TIGR02168  941 L-------------QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTA 1007

                          330
                   ....*....|..
gi 2217334288  702 QQEAATTQLEQL 713
Cdd:TIGR02168 1008 QKEDLTEAKETL 1019
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1380-1899 5.67e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.06  E-value: 5.67e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1380 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALL-------TQTLAEREEEVETLRGQIQELEKQRE 1452
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLeaeiedlRETIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1453 MQKAALELLSLDLKKRNQEVDLQQEQIQELEK----CRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQL 1528
Cdd:PRK02224   290 ELEEERDDLLAEAGLDDADAEAVEARREELEDrdeeLRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1529 LELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKE----LEGQRETQRVALTHLTLDLEERSQEL 1604
Cdd:PRK02224   370 SELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREerdeLREREAELEATLRTARERVEEAEALL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1605 QAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQ------ELMLQKERIQVLEDQRTRQT 1678
Cdd:PRK02224   450 EAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDlveaedRIERLEERREDLEELIAERR 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1679 KILEEDLEQIKlSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVEcQQEHIHELQELKDQLEQQ 1758
Cdd:PRK02224   530 ETIEEKRERAE-ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIRTLLAAIADAEDE 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1759 LQGLHRKVGETSLLLSQReqeivvlQQQLQEAREQ-GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVK 1837
Cdd:PRK02224   608 IERLREKREALAELNDER-------RERLAEKRERkRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQ 680

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217334288 1838 EKADALQGALEQAHmTLKERHGELQDHKEQARRLEEElavegrrVQALEEVLGDLRAESREQ 1899
Cdd:PRK02224   681 AEIGAVENELEELE-ELRERREALENRVEALEALYDE-------AEELESMYGDLRAELRQR 734
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
398-888 5.86e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.06  E-value: 5.86e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  398 RRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRq 477
Cdd:PRK02224   249 RREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELR- 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  478 qlEVLEQEAWRLRRVNVELQLQGDSAQGQKEeqqeelhlavrERERLQEMLMGLEAKQSESLSELITLREALESSHLEGE 557
Cdd:PRK02224   328 --DRLEECRVAAQAHNEEAESLREDADDLEE-----------RAEELREEAAELESELEEAREAVEDRREEIEELEEEIE 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  558 LLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKL-SALNEALALDKVGLNQQLLQLEEENQSVCSRMEAA 636
Cdd:PRK02224   395 ELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTArERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDR 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  637 EQarnalqvdLAEAEKRREALWEKNTHLEAQLQKAEEAgAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQE 716
Cdd:PRK02224   475 ER--------VEELEAELEDLEEEVEEVEERLERAEDL-VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRER 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  717 AKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLssakELLESSLFEAQQQNSVIEVTKGQLEVQIQT 796
Cdd:PRK02224   546 AAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL----ERIRTLLAAIADAEDEIERLREKREALAEL 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  797 VTQAKEVIQGE---VRCLKLELDTER-SQAEQERDAAARQLAQAE------QEGKTALEQQKAAHEKEVNQLREKweKER 866
Cdd:PRK02224   622 NDERRERLAEKrerKRELEAEFDEARiEEAREDKERAEEYLEQVEekldelREERDDLQAEIGAVENELEELEEL--RER 699

                          490       500
                   ....*....|....*....|..
gi 2217334288  867 SWHQQELAKALESLEREKMELE 888
Cdd:PRK02224   700 REALENRVEALEALYDEAEELE 721
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1308-1884 1.38e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 63.98  E-value: 1.38e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1308 QNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTA----QVEHLQAAVVEARAQASAAGILEED-LR 1382
Cdd:pfam15921  266 QDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEDkIE 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1383 TARSALKLKNEEV-ESERERAQALQEQGELkvaqgkalQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELL 1461
Cdd:pfam15921  346 ELEKQLVLANSELtEARTERDQFSQESGNL--------DDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHL 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1462 SLDLKKRNQEVDLQQEQIQELE-KCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEhqllELEKKDQMIES 1540
Cdd:pfam15921  418 RRELDDRNMEVQRLEALLKAMKsECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVE----ELTAKKMTLES 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1541 QRGQVQDLKKQLVTLECLALELEENHHKMECQQKL----IKELEGQRETQRVALTH---LTLDLEERSQELQAQSSQIHD 1613
Cdd:pfam15921  494 SERTVSDLTASLQEKERAIEATNAEITKLRSRVDLklqeLQHLKNEGDHLRNVQTEceaLKLQMAEKDKVIEILRQQIEN 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1614 LES-------HSTVLARELQERDQEVKSQREQIEE---LQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEE 1683
Cdd:pfam15921  574 MTQlvgqhgrTAGAMQVEKAQLEKEINDRRLELQEfkiLKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQ 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1684 DLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLH 1763
Cdd:pfam15921  654 ERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQ 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1764 RKVGETSLLLSQREQEIvvlqQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADAL 1843
Cdd:pfam15921  734 KQITAKRGQIDALQSKI----QFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANM 809

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 2217334288 1844 QGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQA 1884
Cdd:pfam15921  810 EVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 631-1451 1.86e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.55  E-value: 1.86e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  631 SRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDI-QEEKEEIQKKLSESRHQQEAATTQ 709
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERS 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  710 LEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQ 789
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKD 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  790 LEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQ--AEQEGKTALEQQKAAHEKEVNQLREKWEKERs 867
Cdd:TIGR02169  390 YREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKinELEEEKEDKALEIKKQEWKLEQLAADLSKYE- 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  868 whqqelaKALESLEREKMELEMRLKEQQTEMEAIQAQREE-ERTQAESALCQMQLETEKERV-SLLETLLQTQKELADAS 945
Cdd:TIGR02169  469 -------QELYDLKEEYDRVEKELSKLQRELAEAEAQARAsEERVRGGRAVEEVLKASIQGVhGTVAQLGSVGERYATAI 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  946 QQLERLRQDMKVQKLKEQETTGILQTQLQEAQR----ELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVED-----LK 1016
Cdd:TIGR02169  542 EVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRatflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafkyvFG 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1017 SQLVAQD--------DSQRLV--EQEVQEK---------------------LRETQEYNRIQKELEREKASLTLSLMEKE 1065
Cdd:TIGR02169  622 DTLVVEDieaarrlmGKYRMVtlEGELFEKsgamtggsraprggilfsrsePAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1066 QRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEadflaqeaqllEELEASHITEQQLRASLWAQ 1145
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE-----------QEIENVKSELKELEARIEEL 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1146 EAKAAQLQLRLRSTESQLealaaeqqpgnqaqaqaqLASLYSALQQALGSVCESRPELSGggdsapsvwglepdqngars 1225
Cdd:TIGR02169  771 EEDLHKLEEALNDLEARL------------------SHSRIPEIQAELSKLEEEVSRIEA-------------------- 812

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1226 lfkrgplltalSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWE 1305
Cdd:TIGR02169  813 -----------RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1306 GKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEdlrtar 1385
Cdd:TIGR02169  882 SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLED------ 955

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217334288 1386 saLKLKNEEVEserERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQR 1451
Cdd:TIGR02169  956 --VQAELQRVE---EEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1599-2312 1.98e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.15  E-value: 1.98e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1599 ERSQELQAQSSQIHDLESHstVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQT 1678
Cdd:TIGR02168  210 EKAERYKELKAELRELELA--LLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1679 KILEE------DLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELK 1752
Cdd:TIGR02168  288 KELYAlaneisRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1753 DQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQgelKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQ 1832
Cdd:TIGR02168  368 EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR---LERLEDRRERLQQEIEELLKKLEEAELKELQAELEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1833 EERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAE 1912
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1913 QAQEHEVETR-------ALQDSwlqAQAVLKERDQE-LEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHL 1984
Cdd:TIGR02168  525 LSELISVDEGyeaaieaALGGR---LQAVVVENLNAaKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFL 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1985 LEQAELSRSLEASTATLQA---------SLDACQAHSRQLEEALRI--QEGE-IQDQDLRYQEDVQQLQQALAQRDEELR 2052
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSYllggvlvvdDLDNALELAKKLRPGYRIvtLDGDlVRPGGVITGGSAKTNSSILERRREIEE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2053 HQQEREQLLEKSLAQRVQENMIQEKQNLGQEReeeeirglhqsVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTS 2132
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEE-----------LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2133 PMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQ 2212
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2213 DELELTRRALEkerlhspgaTSTAELGSRGEQGVQLgEVSGVEAEPSPDGMEKQswrqrLEHLQQAVARLEIDRSRLQRH 2292
Cdd:TIGR02168  831 RRIAATERRLE---------DLEEQIEELSEDIESL-AAEIEELEELIEELESE-----LEALLNERASLEEALALLRSE 895

                          730       740
                   ....*....|....*....|....
gi 2217334288 2293 NVQLRSTLEQVERE----RRKLKR 2312
Cdd:TIGR02168  896 LEELSEELRELESKrselRRELEE 919
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 524-1069 2.45e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 62.83  E-value: 2.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  524 LQEMLMGLEAKQSESLSELITLREALESSHLEGELLrQEQTEVTAALARAEQSI--AELSSSENTLKTEVADLRAAAVKL 601
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSI-QSQLEIIQEQARNQNSMymRQLSDLESTVSQLRSELREAKRMY 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  602 SALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQAD 681
Cdd:pfam15921  341 EDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  682 LRDIQEEKEEIQKKL----SESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEAL---VREKAALEVRLQAVERDRQD 754
Cdd:pfam15921  421 LDDRNMEVQRLEALLkamkSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLrkvVEELTAKKMTLESSERTVSD 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  755 LAEQLQGLSSAkelLESSLFEAQQQNSVIEVTKGQLEvQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLA 834
Cdd:pfam15921  501 LTASLQEKERA---IEATNAEITKLRSRVDLKLQELQ-HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQ 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  835 QAEQEGKTA--LEQQKAAHEKEVNqlrekwekERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIqaqreeerTQA 912
Cdd:pfam15921  577 LVGQHGRTAgaMQVEKAQLEKEIN--------DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKL--------VNA 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  913 ESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKeaarQHRDDLA 992
Cdd:pfam15921  641 GSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELE----QTRNTLK 716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  993 ALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEV----QEKLRETQEYNRIQKEL-----EREKASLTLSLME 1063
Cdd:pfam15921  717 SMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMtnanKEKHFLKEEKNKLSQELstvatEKNKMAGELEVLR 796


                   ....*.
gi 2217334288 1064 KEQRLL 1069
Cdd:pfam15921  797 SQERRL 802
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
380-860 2.97e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.63  E-value: 2.97e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  380 DYQDADKALTLVRSVLT-----RRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVD- 453
Cdd:COG4913    263 RYAAARERLAELEYLRAalrlwFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEq 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  454 LQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAV-----------RERE 522
Cdd:COG4913    343 LEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALaeaeaalrdlrRELR 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  523 RLQEMLMGLEAKQSESLSELITLREALESsHLE---------GELL--RQEQTEVTAALARAeqsiaeLSSSENTLKTEV 591
Cdd:COG4913    423 ELEAEIASLERRKSNIPARLLALRDALAE-ALGldeaelpfvGELIevRPEEERWRGAIERV------LGGFALTLLVPP 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  592 ADLRAAAVKLSALNEALALD--KVGLNQQLLQLEE-ENQSVCSRMEAAE------------QARNALQVDLAEAEKR--- 653
Cdd:COG4913    496 EHYAAALRWVNRLHLRGRLVyeRVRTGLPDPERPRlDPDSLAGKLDFKPhpfrawleaelgRRFDYVCVDSPEELRRhpr 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  654 ----------REALWEKNTHLEAQLQ-----KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAK 718
Cdd:COG4913    576 aitragqvkgNGTRHEKDDRRRIRSRyvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE 655

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  719 RQEEVLARAvqekeALVREKAALEVRLQAVERDRQDLA---EQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQ 795
Cdd:COG4913    656 YSWDEIDVA-----SAEREIAELEAELERLDASSDDLAaleEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELD 730

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288  796 TVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLRE 860
Cdd:COG4913    731 ELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 402-1057 3.04e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 3.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  402 VQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEV 481
Cdd:TIGR02169  296 IGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  482 LEQEAWRLRRVNVELQLQGD-------SAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESShl 554
Cdd:TIGR02169  376 VDKEFAETRDELKDYREKLEklkreinELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ-- 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  555 EGEL----------------LRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALaldkVGLNQQ 618
Cdd:TIGR02169  454 EWKLeqlaadlskyeqelydLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGV----HGTVAQ 529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  619 LLQLEEENQSVCsrmEAAEQARNALQV--DLAEAEKRREALWEKNT------------HLEAQLQKAEEAGAELQA-DLR 683
Cdd:TIGR02169  530 LGSVGERYATAI---EVAAGNRLNNVVveDDAVAKEAIELLKRRKAgratflplnkmrDERRDLSILSEDGVIGFAvDLV 606

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  684 DIQEEKEEIQKKL-----------SESRHQQEAATTQLEQLHQE----------AKRQEEVLARAVQEKEALVREkaale 742
Cdd:TIGR02169  607 EFDPKYEPAFKYVfgdtlvvedieAARRLMGKYRMVTLEGELFEksgamtggsrAPRGGILFSRSEPAELQRLRE----- 681

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  743 vRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQ- 821
Cdd:TIGR02169  682 -RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSEl 760

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  822 -------AEQERDAAARQLAQAEQEGKTALE--QQKAAHEKEVNQLREKWEKErswhQQELAKALESLEREKMELEMRLK 892
Cdd:TIGR02169  761 keleariEELEEDLHKLEEALNDLEARLSHSriPEIQAELSKLEEEVSRIEAR----LREIEQKLNRLTLEKEYLEKEIQ 836

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  893 EQQTEMEAIQAQREEERtqAESALCQMQLETEKERVSLLET-LLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQT 971
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIE--KEIENLNGKKEELEEELEELEAaLRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEK 914

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  972 Q-----LQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRI 1046
Cdd:TIGR02169  915 KrkrlsELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEK 994

                          730
                   ....*....|.
gi 2217334288 1047 QKELEREKASL 1057
Cdd:TIGR02169  995 RAKLEEERKAI 1005
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 401-1112 4.87e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 4.87e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  401 AVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDL-QGEVDSLSKERELLQKAREELRQQL 479
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSI 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  480 EVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELL 559
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  560 RQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQA 639
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  640 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLE-----QLH 714
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvaagnRLN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  715 QEAKRQEEVLARAVQ---EKEA-------------------LVREKAALEVRLQAVERDRQ------------------D 754
Cdd:TIGR02169  551 NVVVEDDAVAKEAIEllkRRKAgratflplnkmrderrdlsILSEDGVIGFAVDLVEFDPKyepafkyvfgdtlvvediE 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  755 LAEQLQG----LSSAKELLESS--LFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLEL---DTERSQAEQE 825
Cdd:TIGR02169  631 AARRLMGkyrmVTLEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELrriENRLDELSQE 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  826 RDAAARQLAQAEQEGKtALEQQKAAHEKEVNQLREKwekerswhQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQR 905
Cdd:TIGR02169  711 LSDASRKIGEIEKEIE-QLEQEEEKLKERLEELEED--------LSSLEQEIENVKSELKELEARIEELEEDLHKLEEAL 781

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  906 EE-ERTQAESALCQMQLET---EKERVSL----------LETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQT 971
Cdd:TIGR02169  782 NDlEARLSHSRIPEIQAELsklEEEVSRIearlreieqkLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNG 861

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  972 QLQEAQRELKEAA---RQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQK 1048
Cdd:TIGR02169  862 KKEELEEELEELEaalRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKG 941

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217334288 1049 ELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALrQDMQEAQGEQKELSAQMELLRQEVKE 1112
Cdd:TIGR02169  942 EDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAI-QEYEEVLKRLDELKEKRAKLEEERKA 1004
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 615-939 5.21e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 5.21e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  615 LNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQK 694
Cdd:TIGR02169  707 LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA 786

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  695 KLSESRHQQeaATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLF 774
Cdd:TIGR02169  787 RLSHSRIPE--IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  775 EAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEqegktALEQQKAAHEKE 854
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE-----ALEEELSEIEDP 939

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  855 VNQLREKWEKERSWHQqeLAKALESLEREKMELEmrlkeqQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETL 934
Cdd:TIGR02169  940 KGEDEEIPEEELSLED--VQAELQRVEEEIRALE------PVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEE 1011


                   ....*
gi 2217334288  935 LQTQK 939
Cdd:TIGR02169 1012 YEKKK 1016
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
395-982 6.67e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 6.67e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  395 LTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEE--EGKALRQRLQKLTGER--DTLAGQTVDLQGEVDSLSKERELLQK 470
Cdd:COG4913    237 LERAHEALEDAREQIELLEPIRELAERYAAARERlaELEYLRAALRLWFAQRrlELLEAELEELRAELARLEAELERLEA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  471 AREELRQQLEVLEQEAWRLRRVNVElqlqgdSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALE 550
Cdd:COG4913    317 RLDALREELDELEAQIRGNGGDRLE------QLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAA 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  551 SshlEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKL--------SALNEALALDKVGLN--QQLL 620
Cdd:COG4913    391 A---LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIparllalrDALAEALGLDEAELPfvGELI 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  621 QLEEENQSvcSRMeAAEQA----RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKL 696
Cdd:COG4913    468 EVRPEEER--WRG-AIERVlggfALTLLVPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKP 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  697 SESRHQQEAATTQ---------LEQLHQEAK-----------------------RQEEVL-ARAVQEKEALVREKAALEV 743
Cdd:COG4913    545 HPFRAWLEAELGRrfdyvcvdsPEELRRHPRaitragqvkgngtrhekddrrriRSRYVLgFDNRAKLAALEAELAELEE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  744 RLQAVERDRQDLAEQLQGLSSAKELLE--SSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQgevrclklELDTERSQ 821
Cdd:COG4913    625 ELAEAEERLEALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELEAELERLDASSDDLA--------ALEEQLEE 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  822 AEQERDAAARQLAQAEQEgKTALEQQKAAHEKEVNQLREKWE----KERSWHQQELAKALESLEREKMELEMRlKEQQTE 897
Cdd:COG4913    697 LEAELEELEEELDELKGE-IGRLEKELEQAEEELDELQDRLEaaedLARLELRALLEERFAAALGDAVERELR-ENLEER 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  898 MEAIQAQREEERTQAESALCQMQLETEKERVSL---LETLLQTQKELAD-ASQQLERLRQDMKvQKLKEQETTGI--LQT 971
Cdd:COG4913    775 IDALRARLNRAEEELERAMRAFNREWPAETADLdadLESLPEYLALLDRlEEDGLPEYEERFK-ELLNENSIEFVadLLS 853

                          650
                   ....*....|.
gi 2217334288  972 QLQEAQRELKE 982
Cdd:COG4913    854 KLRRAIREIKE 864
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1422-1875 6.92e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.19  E-value: 6.92e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1422 NLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELekcRSVLEHLPMAVQEREQ 1501
Cdd:TIGR04523  198 KLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQL---KDEQNKIKKQLSEKQK 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1502 KLTVQREQIRELEKdretQRNVLEHQLLELEKKDQM---------IESQRGQVQDLKKQLVTLECLALELEENHHKMEcq 1572
Cdd:TIGR04523  275 ELEQNNKKIKELEK----QLNQLKSEISDLNNQKEQdwnkelkseLKNQEKKLEEIQNQISQNNKIISQLNEQISQLK-- 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1573 qKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQD 1652
Cdd:TIGR04523  349 -KELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1653 LERRDQELMLQKERIQVLEDQRTRQTKILEedleqiklslrergrELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILR 1732
Cdd:TIGR04523  428 IERLKETIIKNNSEIKDLTNQDSVKELIIK---------------NLDNTRESLETQLKVLSRSINKIKQNLEQKQKELK 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1733 DKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREqgELKEQSLQSQLDEAQRAL 1812
Cdd:TIGR04523  493 SKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF--ELKKENLEKEIDEKNKEI 570

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217334288 1813 AQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEEL 1875
Cdd:TIGR04523  571 EELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSII 633
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 519-1134 7.84e-09

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 61.28  E-value: 7.84e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  519 RERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAA 598
Cdd:pfam05483   85 KEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETC 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  599 VKLSALNEALALDKVGLNQQLLQLeeeNQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKaEEAGAEL 678
Cdd:pfam05483  165 ARSAEKTKKYEYEREETRQVYMDL---NNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKK-EINDKEK 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  679 QADLRDIQEEKEEiqKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQ-------AVERD 751
Cdd:pfam05483  241 QVSLLLIQITEKE--NKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQrsmstqkALEED 318

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  752 RQDLAEQLQGLSSAKELLESSLFEAQQQNSVI----EVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERD 827
Cdd:pfam05483  319 LQIATKTICQLTEEKEAQMEELNKAKAAHSFVvtefEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTK 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  828 AAARQLAQAEQEGKTALEQQKAAHEkevNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREE 907
Cdd:pfam05483  399 FKNNKEVELEELKKILAEDEKLLDE---KKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVED 475

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  908 ERTQAESALCQMQLETEKERVSLLETLLQTQkELADASQQLERLRQDMKVQKLKEQETTGILQTqlqeaqreLKEAARQH 987
Cdd:pfam05483  476 LKTELEKEKLKNIELTAHCDKLLLENKELTQ-EASDMTLELKKHQEDIINCKKQEERMLKQIEN--------LEEKEMNL 546

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  988 RDDLAALQEEsssllqdkmdLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQR 1067
Cdd:pfam05483  547 RDELESVREE----------FIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQE 616

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217334288 1068 LLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHIT 1134
Cdd:pfam05483  617 NKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAI 683
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 634-862 1.10e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.78  E-value: 1.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  634 EAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQL 713
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  714 HQEAKRQEEVLARAVQEKEALV----REKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQ 789
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLALllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217334288  790 LEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKW 862
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1363-1587 1.57e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.39  E-value: 1.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1363 AVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRG 1442
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1443 QIQELEKQREMQKAALELLSLDLKKRNQ----EVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRE 1518
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1519 TQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQ-QKLIKELEGQRETQR 1587
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEElEALIARLEAEAAAAA 240
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 447-805 1.61e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.47  E-value: 1.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  447 LAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRvnvelqlqgdsaqgqkeeQQEELHLAVRERERLQE 526
Cdd:TIGR02169  665 GILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ------------------ELSDASRKIGEIEKEIE 726

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  527 MLMGLEAKQSESLSELitlREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAavKLSALNE 606
Cdd:TIGR02169  727 QLEQEEEKLKERLEEL---EEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIP--EIQAELS 801

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  607 ALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQ 686
Cdd:TIGR02169  802 KLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLE 881

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  687 EEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVER------DRQDLAEQLQ 760
Cdd:TIGR02169  882 SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEipeeelSLEDVQAELQ 961

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 2217334288  761 GLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQ 805
Cdd:TIGR02169  962 RVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 246-491 1.70e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 1.70e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  246 LLLLLAKTQELEKEAHERSQELIQLKSQgdleKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELME 325
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQE----IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  326 HEASLSRNAQEEKLSLQQVIKDITQVMVEegdniAQGSGHENSLELdssIFSQFDYQDADKALTLVRSVLTRRRQAVQDL 405
Cdd:COG4942     84 ELAELEKEIAELRAELEAQKEELAELLRA-----LYRLGRQPPLAL---LLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  406 RQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQE 485
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235


                   ....*.
gi 2217334288  486 AWRLRR 491
Cdd:COG4942    236 AAAAAE 241
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 873-1111 2.04e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 2.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  873 LAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQlETEKERVSLLETLLQTQKELADASQQLERLR 952
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  953 QDMKVQKLKEQETTGILQTQLQEAQRelkeAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQE 1032
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYR----LGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAAL 165

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1033 VQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVK 1111
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 651-1340 2.07e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 60.13  E-value: 2.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  651 EKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQE 730
Cdd:pfam15921  102 EKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLS 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  731 KEALVREKAALEVRLQAV------ERDRQD----------LAEQLQGLSSAKELLESSLFEAQQQnsvIEVTKGQLEVQI 794
Cdd:pfam15921  182 HEGVLQEIRSILVDFEEAsgkkiyEHDSMStmhfrslgsaISKILRELDTEISYLKGRIFPVEDQ---LEALKSESQNKI 258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  795 QTVTQAKeviQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREkWEKERSWHQQELA 874
Cdd:pfam15921  259 ELLLQQH---QDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSD-LESTVSQLRSELR 334

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  875 KALESLEREKMELEMRLKEQQTEMeaIQAQREEERTQAESALCQMQLEtekervSLLETLLQTQKELADASQQLERL--- 951
Cdd:pfam15921  335 EAKRMYEDKIEELEKQLVLANSEL--TEARTERDQFSQESGNLDDQLQ------KLLADLHKREKELSLEKEQNKRLwdr 406

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  952 -----------RQDMKVQKLKEQETTGILQTQLQEAQRELKE---AARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKS 1017
Cdd:pfam15921  407 dtgnsitidhlRRELDDRNMEVQRLEALLKAMKSECQGQMERqmaAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTA 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1018 QLVAQDDSQRLVEQ---EVQEKLRETQEYNriqKELEREKASLTLSLMEKEQrllVLQEADSIR--QQELSALRQDMQEA 1092
Cdd:pfam15921  487 KKMTLESSERTVSDltaSLQEKERAIEATN---AEITKLRSRVDLKLQELQH---LKNEGDHLRnvQTECEALKLQMAEK 560

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1093 QGEQKELSAQMELLRQEVKE---KEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTEsqleaLAAE 1169
Cdd:pfam15921  561 DKVIEILRQQIENMTQLVGQhgrTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE-----LEKV 635

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1170 QQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGggdsapsvwgLEPDQNGARSLFKRGPLLTALSAEAVASALHKLH 1249
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNS----------LSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQ 705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1250 QDLWKTQQTR----------------------------DVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEK 1301
Cdd:pfam15921  706 SELEQTRNTLksmegsdghamkvamgmqkqitakrgqiDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 2217334288 1302 SKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQ 1340
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQ 824
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1490-2116 2.11e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 60.13  E-value: 2.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1490 EHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENH-HK 1568
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTvHE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1569 MECQQKLIKELEGQRETQRVALTHLTLDLEERSQEL--------QAQSSQIHDLESHSTV--------LARELQERDQEV 1632
Cdd:pfam15921  154 LEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIrsilvdfeEASGKKIYEHDSMSTMhfrslgsaISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1633 KSQREQIEELQRQKEHLTQDLERRdQELMLQKERIQVleDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEE 1712
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNK-IELLLQQHQDRI--EQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1713 GKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHElqelkdQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEARE 1792
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIE------ELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLA 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1793 QGELKEQSLQSQLDEAQRaLAQRDQELEALQQEQQQAQGQEERVKEKADAL--------QGALEQAHMTLKERH------ 1858
Cdd:pfam15921  385 DLHKREKELSLEKEQNKR-LWDRDTGNSITIDHLRRELDDRNMEVQRLEALlkamksecQGQMERQMAAIQGKNeslekv 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1859 ----GELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCaeqaqeheVETRALQDSWLQAQAV 1934
Cdd:pfam15921  464 ssltAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEI--------TKLRSRVDLKLQELQH 535

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1935 LKERDQELEALRAESQSSRHQEEAARARAEALQEalgkahaALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQ 2014
Cdd:pfam15921  536 LKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQ-------QIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQE 608

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2015 LEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRH----QQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIR 2090
Cdd:pfam15921  609 FKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSE 688

                          650       660
                   ....*....|....*....|....*.
gi 2217334288 2091 GLHQSVRELQLTLAQKEQEILELRET 2116
Cdd:pfam15921  689 EMETTTNKLKMQLKSAQSELEQTRNT 714
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1239-1955 2.19e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.08  E-value: 2.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1239 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMEL 1318
Cdd:TIGR02169  332 DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1319 HETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESE 1398
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1399 RERAQALQEQGELKVAQGKALQENLalltqtlaerEEEVETLRGQIQELEKQREMQKAALEL-LSLDLKKRNQEVDLQQE 1477
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAVEEVL----------KASIQGVHGTVAQLGSVGERYATAIEVaAGNRLNNVVVEDDAVAK 561

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1478 QIQELEKCRSVlehlpmavqEREQKLTVQREQIRELEKDRETQRNVLEHqLLELEKKDQMIESQRGQVqdLKKQLVTLEC 1557
Cdd:TIGR02169  562 EAIELLKRRKA---------GRATFLPLNKMRDERRDLSILSEDGVIGF-AVDLVEFDPKYEPAFKYV--FGDTLVVEDI 629

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1558 LALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQRE 1637
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1638 QIEELQRQKEHLTQDLERRDQELMLQKERIqvledqrtrqtKILEEDLEQIKLSLRERGRELTTQRQLMQERaEEGKGPS 1717
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERL-----------EELEEDLSSLEQEIENVKSELKELEARIEEL-EEDLHKL 777

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1718 KAQRGSLEHmklilRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQ---- 1793
Cdd:TIGR02169  778 EEALNDLEA-----RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQiksi 852

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1794 ------GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQ 1867
Cdd:TIGR02169  853 ekeienLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1868 ARRLEEELAvEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEvETRALQDSWLQAQAVLKERDQELEALRA 1947
Cdd:TIGR02169  933 LSEIEDPKG-EDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYE-EVLKRLDELKEKRAKLEEERKAILERIE 1010


                   ....*...
gi 2217334288 1948 ESQSSRHQ 1955
Cdd:TIGR02169 1011 EYEKKKRE 1018
mukB PRK04863
chromosome partition protein MukB;
646-1015 2.24e-08

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 59.97  E-value: 2.24e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  646 DLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLeQLHQEAKRQEEVLA 725
Cdd:PRK04863   273 DYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKIE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  726 RAVQEKEALV--------------REKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLE 791
Cdd:PRK04863   352 RYQADLEELEerleeqnevveeadEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERAKQLCG 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  792 VQIQTVTQAKEVIQgEVRCLKLELDTERSQAEQE---RDAAARQLAQAEQEGKTALEQ--QKAAHEKEVNQLREkWEKer 866
Cdd:PRK04863   432 LPDLTADNAEDWLE-EFQAKEQEATEELLSLEQKlsvAQAAHSQFEQAYQLVRKIAGEvsRSEAWDVARELLRR-LRE-- 507

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  867 swhQQELAKALESLEREKMELEMRLKEQQTEMEAIQ--AQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADA 944
Cdd:PRK04863   508 ---QRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAefCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMAL 584

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  945 SQQLERLRQDmkVQKLKEQETTGI--------LQTQLQEAQ---RELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVE 1013
Cdd:PRK04863   585 RQQLEQLQAR--IQRLAARAPAWLaaqdalarLREQSGEEFedsQDVTEYMQQLLERERELTVERDELAARKQALDEEIE 662


                   ..
gi 2217334288 1014 DL 1015
Cdd:PRK04863   663 RL 664
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 853-1711 2.44e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.60  E-value: 2.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  853 KEVNQLREKWEKERSWHQQELA-----KALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKER 927
Cdd:pfam02463  142 GKIEIIAMMKPERRLEIEEEAAgsrlkRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  928 VSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQhrddlaalQEESSSLLQDKMD 1007
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKE--------KKLQEEELKLLAK 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1008 LQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRetqeynRIQKELEREKASL-------------TLSLMEKEQRLLVLQEA 1074
Cdd:pfam02463  294 EEEELKSELLKLERRKVDDEEKLKESEKEKK------KAEKELKKEKEEIeelekelkeleikREAEEEEEEELEKLQEK 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1075 DSIRQQELSALRQDMQEAQGEQKELsAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQ-----QLRASLWAQEAKA 1149
Cdd:pfam02463  368 LEQLEEELLAKKKLESERLSSAAKL-KEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEEleileEEEESIELKQGKL 446

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1150 AQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKR 1229
Cdd:pfam02463  447 TEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIIS 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1230 GPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQN 1309
Cdd:pfam02463  527 AHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLA 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1310 SLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASaagiLEEDLRTARSALK 1389
Cdd:pfam02463  607 QLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLS----ELTKELLEIQELQ 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1390 LKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRN 1469
Cdd:pfam02463  683 EKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEK 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1470 QEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLK 1549
Cdd:pfam02463  763 EEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALEL 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1550 KQLVTLECLALELEENHHKMECQQKLIKELEGQR-ETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQER 1628
Cdd:pfam02463  843 KEEQKLEKLAEEELERLEEEITKEELLQELLLKEeELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEER 922

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1629 DQEVKSQREQIEELQRqKEHLTQDLERRDQE--LMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLM 1706
Cdd:pfam02463  923 IKEEAEILLKYEEEPE-ELLLEEADEKEKEEnnKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLE 1001


                   ....*
gi 2217334288 1707 QERAE 1711
Cdd:pfam02463 1002 EEKKK 1006
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1278-1502 3.49e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.24  E-value: 3.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1278 AEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQV 1357
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1358 EHLQAAVVEARAQASAAGileedlRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEV 1437
Cdd:COG4942    100 EAQKEELAELLRALYRLG------RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1438 ETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQK 1502
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1228-1457 3.75e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.24  E-value: 3.75e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1228 KRGPLLTALSAEAVASALHKLHQDLwktQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGK 1307
Cdd:COG4942      1 MRKLLLLALLLALAAAAQADAAAEA---EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1308 QNSLESELMELHETMASLQSRLRR---------AELQRMEAQGERELLQAAK---------ENLTAQVEHLQAAVVEARA 1369
Cdd:COG4942     78 LAALEAELAELEKEIAELRAELEAqkeelaellRALYRLGRQPPLALLLSPEdfldavrrlQYLKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1370 QASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQgkaLQENLALLTQTLAEREEEVETLRGQIQELEK 1449
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIARLEA 234


                   ....*...
gi 2217334288 1450 QREMQKAA 1457
Cdd:COG4942    235 EAAAAAER 242
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 251-601 9.93e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 9.93e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  251 AKTQELEKEAHERSQELIQLKSQGDL---EKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHE 327
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEEleeELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  328 ASLSRNAQEEKLSLQQVIKDITQVMveegdniAQGSGHENSLELDSSIFSqfdyqDADKALTLVRSVLTRRRQAVQDLRQ 407
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELE-------AQIEQLKEELKALREALD-----ELRAELTLLNEEAANLRERLESLER 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  408 QLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAW 487
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  488 RLRRVNVELQLQ-GDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESshlegelLRQEQTEV 566
Cdd:TIGR02168  912 ELRRELEELREKlAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR-------LENKIKEL 984

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 2217334288  567 TAALARAEQSIAELSSSENTLKTEVADLRAAAVKL 601
Cdd:TIGR02168  985 GPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETL 1019
PTZ00121 PTZ00121
MAEBL; Provisional
 1264-1901 1.04e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.84  E-value: 1.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1264 DQVQKLEERLTDTEAEKSQVHTELQDLQR-QLSQNQEEKSKWEGKQNSLE-SELMELHETmaslqSRLRRAELQRmEAQG 1341
Cdd:PTZ00121  1137 EDARKAEEARKAEDAKRVEIARKAEDARKaEEARKAEDAKKAEAARKAEEvRKAEELRKA-----EDARKAEAAR-KAEE 1210

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1342 ERELLQAAKENLTAQVEHLQAaVVEARAQASAAGILEEDlRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQE 1421
Cdd:PTZ00121  1211 ERKAEEARKAEDAKKAEAVKK-AEEAKKDAEEAKKAEEE-RNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1422 NLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELL--SLDLKKRNQEVDLQQE-QIQELEKCRSVLEHLPMAVQE 1498
Cdd:PTZ00121  1289 KKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKkkADAAKKKAEEAKKAAEaAKAEAEAAADEAEAAEEKAEA 1368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1499 REQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKE 1578
Cdd:PTZ00121  1369 AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADE 1448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1579 LEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQRE---QIEELQRQKEHLTQDLER 1655
Cdd:PTZ00121  1449 AKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEakkKADEAKKAEEAKKADEAK 1528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1656 RDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQrgslehMKLILRDKE 1735
Cdd:PTZ00121  1529 KAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR------IEEVMKLYE 1602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1736 KEVECQQEHIHELQELKDQLEQQLQGlhRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRAlAQR 1815
Cdd:PTZ00121  1603 EEKKMKAEEAKKAEEAKIKAEELKKA--EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK-AEE 1679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1816 DQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHK---EQARRLEEELAVEGRRVQALEEVLGDL 1892
Cdd:PTZ00121  1680 AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKikaEEAKKEAEEDKKKAEEAKKDEEEKKKI 1759


                   ....*....
gi 2217334288 1893 RAESREQEK 1901
Cdd:PTZ00121  1760 AHLKKEEEK 1768
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
971-1168 1.09e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.62  E-value: 1.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  971 TQLQEAQRELKEAARQhRDDLAALQEESSSLLQDKMDLQKQvEDLKSQLVAQDDSQRLVEQEvQEKLRETQEYNRIQKEL 1050
Cdd:COG4913    235 DDLERAHEALEDAREQ-IELLEPIRELAERYAAARERLAEL-EYLRAALRLWFAQRRLELLE-AELEELRAELARLEAEL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1051 EREKASLTLSLMEKEQRLLVLQEADSIR----QQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLE 1126
Cdd:COG4913    312 ERLEARLDALREELDELEAQIRGNGGDRleqlEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA 391

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 2217334288 1127 ELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAA 1168
Cdd:COG4913    392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 393-754 1.12e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  393 SVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGErdtlagqTVDLQGEVDSLSKERELLQKAR 472
Cdd:TIGR02169  667 LFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK-------IGEIEKEIEQLEQEEEKLKERL 739

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  473 EELRQQLEVLEQEAWRLRRVNVEL-----QLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLRE 547
Cdd:TIGR02169  740 EELEEDLSSLEQEIENVKSELKELearieELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQ 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  548 ALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQ 627
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR 899

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  628 SVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELqADLRDIQEEKEEIQKKLSESRHQQEAAt 707
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE-LSLEDVQAELQRVEEEIRALEPVNMLA- 977

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 2217334288  708 tqLEQLHQEAKRQEEVlaraVQEKEALVREKAALEVRLQAVERDRQD 754
Cdd:TIGR02169  978 --IQEYEEVLKRLDEL----KEKRAKLEEERKAILERIEEYEKKKRE 1018
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
267-778 1.36e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.36  E-value: 1.36e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  267 LIQLKSQ-GDLEKAELQDRVTELSALLTQSQKQNEDYEK--------------MIKALRETVEILETNHTELMEHEASLS 331
Cdd:PRK02224   189 LDQLKAQiEEKEEKDLHERLNGLESELAELDEEIERYEEqreqaretrdeadeVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  332 rNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQfDYQDADKALTLVRSVLTRRRQAVQDLRQQLAG 411
Cdd:PRK02224   269 -ETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEA-RREELEDRDEELRDRLEECRVAAQAHNEEAES 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  412 CQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRR 491
Cdd:PRK02224   347 LREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRE 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  492 VNVELQLQGDSAQGqkeeqqeelhlAVRERERLQEM----LMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVT 567
Cdd:PRK02224   427 REAELEATLRTARE-----------RVEEAEALLEAgkcpECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  568 AALARAEQSI---AELSSSENTLKT---EVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARN 641
Cdd:PRK02224   496 ERLERAEDLVeaeDRIERLEERREDleeLIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVA 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  642 ALQVDLAEAEKRREALwEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSE--SRHQQEAATTQ---LEQLHQE 716
Cdd:PRK02224   576 ELNSKLAELKERIESL-ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEkrERKRELEAEFDearIEEARED 654

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288  717 AKRQEEVLARAVQEKEALVREKAALEVRLQAVERD---RQDLAEQLQGLSSAKELLESSLFEAQQ 778
Cdd:PRK02224   655 KERAEEYLEQVEEKLDELREERDDLQAEIGAVENEleeLEELRERREALENRVEALEALYDEAEE 719
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 855-1166 2.04e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 56.67  E-value: 2.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  855 VNQLREKWEKERSWHQQELAKALESLEREKMELEMrlKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETL 934
Cdd:pfam17380  271 LNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEK--EEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERER 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  935 LQTQKELADASQQLERLRQD---MKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQ 1011
Cdd:pfam17380  349 ELERIRQEERKRELERIRQEeiaMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAE 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1012 VEDLKSQLVA--QDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDM 1089
Cdd:pfam17380  429 QEEARQREVRrlEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAM 508

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217334288 1090 QEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLE-ELEASHITEQQLRaslwaqeaKAAQLQLRLRSTESQLEAL 1166
Cdd:pfam17380  509 IEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQqEMEERRRIQEQMR--------KATEERSRLEAMEREREMM 578
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1348-1899 4.59e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.46  E-value: 4.59e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1348 AAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLT 1427
Cdd:PRK03918   186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1428 QTLAEREEEVETLRGQIQELEKQREMQKAALELlsldlkkrNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQR 1507
Cdd:PRK03918   266 ERIEELKKEIEELEEKVKELKELKEKAEEYIKL--------SEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1508 EQIRELEKDRETQRNVLEhQLLELEKKDQMIESQRGQVQDLKKQLVTLEclaleleenhhkMECQQKLIKELEGQRETQR 1587
Cdd:PRK03918   338 ERLEELKKKLKELEKRLE-ELEERHELYEEAKAKKEELERLKKRLTGLT------------PEKLEKELEELEKAKEEIE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1588 VALTHLTL---DLEERSQELQAQSSQIHDLESHSTVLARELQERDQ---------EVKSQREQIEELQRQKEHLTQDLER 1655
Cdd:PRK03918   405 EEISKITArigELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRkelleeytaELKRIEKELKEIEEKERKLRKELRE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1656 RDQELMLQKERIQVLEdqRTRQTKILEEDLEQIKLslrERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKE 1735
Cdd:PRK03918   485 LEKVLKKESELIKLKE--LAEQLKELEEKLKKYNL---EELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1736 KEVECQQEHIHELQELKDQLE--------------QQLQGLHRKVGETSLL---LSQREQEIVVLQQQLQEAREQGELKE 1798
Cdd:PRK03918   560 ELEKKLDELEEELAELLKELEelgfesveeleerlKELEPFYNEYLELKDAekeLEREEKELKKLEEELDKAFEELAETE 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1799 ---QSLQSQLDEAQRALAQRDqeLEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEE-E 1874
Cdd:PRK03918   640 krlEELRKELEELEKKYSEEE--YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKlE 717

                          570       580
                   ....*....|....*....|....*
gi 2217334288 1875 LAVEgrRVQALEEVLGDLRAESREQ 1899
Cdd:PRK03918   718 KALE--RVEELREKVKKYKALLKER 740
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 860-1516 7.30e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.84  E-value: 7.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  860 EKWEKERSWHQQELAKaLESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQK 939
Cdd:pfam12128  244 TKLQQEFNTLESAELR-LSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRS 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  940 ELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLlqdKMDLQKQVEDLKSQL 1019
Cdd:pfam12128  323 ELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKI---KEQNNRDIAGIKDKL 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1020 VAQDdsqrlvEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLlvlqeadSIRQQELSALRQDMQEAQGEQKEL 1099
Cdd:pfam12128  400 AKIR------EARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRL-------KSRLGELKLRLNQATATPELLLQL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1100 SAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRAsLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQ 1179
Cdd:pfam12128  467 ENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEA-LRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAP 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1180 AQLASLYSALQqalgsvcesrPELSGGGDSAPSVWGLEPdqNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTR 1259
Cdd:pfam12128  546 DWEQSIGKVIS----------PELLHRTDLDPEVWDGSV--GGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEAL 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1260 DVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELME-LHETMASLQSRLRR--AELQR 1336
Cdd:pfam12128  614 QSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKaLAERKDSANERLNSleAQLKQ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1337 MEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQG 1416
Cdd:pfam12128  694 LDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKL 773

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1417 KALQENLALLTQTLAEREEEV--------ETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLqqeQIQELEKCRSV 1488
Cdd:pfam12128  774 KREIRTLERKIERIAVRRQEVlryfdwyqETWLQRRPRLATQLSNIERAISELQQQLARLIADTKL---RRAKLEMERKA 850

                          650       660
                   ....*....|....*....|....*...
gi 2217334288 1489 LEHLPMAVQEREQKLTVQREQIRELEKD 1516
Cdd:pfam12128  851 SEKQQVRLSENLRGLRCEMSKLATLKED 878
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 395-609 8.91e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 8.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  395 LTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREE 474
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  475 LRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHL 554
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288  555 EgelLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALA 609
Cdd:COG4942    182 E---LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1279-1816 9.04e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 54.34  E-value: 9.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1279 EKSQVHTELQD-LQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRaELQRMEAQGERELLQAAKENltAQV 1357
Cdd:pfam05483  180 ETRQVYMDLNNnIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKK-EINDKEKQVSLLLIQITEKE--NKM 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1358 EHLQAAVVEARAQASAagiLEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEV 1437
Cdd:pfam05483  257 KDLTFLLEESRDKANQ---LEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEK 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1438 ETlrgQIQELEKQREMQkaALELLSLDLKKRNQEVDLQQEQiQELEKCRSVLEHLPMAVQEREQKLtvqrEQIRELEKDR 1517
Cdd:pfam05483  334 EA---QMEELNKAKAAH--SFVVTEFEATTCSLEELLRTEQ-QRLEKNEDQLKIITMELQKKSSEL----EEMTKFKNNK 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1518 ETQRNVLEHQLLElekkDQMIESQRGQVQDLKKQLVTLECLALELeenhhkMECQQKLIKELEGQRETQRVALTHLTLDL 1597
Cdd:pfam05483  404 EVELEELKKILAE----DEKLLDEKKQFEKIAEELKGKEQELIFL------LQAREKEIHDLEIQLTAIKTSEEHYLKEV 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1598 EERSQELQAQSSQIHDLESHSTVLARELQERDQEVKsqrEQIEELQRQKEHLTQDleRRDQELMLQKerIQVLEDQRTRq 1677
Cdd:pfam05483  474 EDLKTELEKEKLKNIELTAHCDKLLLENKELTQEAS---DMTLELKKHQEDIINC--KKQEERMLKQ--IENLEEKEMN- 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1678 tkiLEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQ 1757
Cdd:pfam05483  546 ---LRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKK 622

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217334288 1758 QLQGLHRKVGETSLLLSQREQEIVVLQQQLQEA----REQGELKEQSLQSQLDEAQRALAQRD 1816
Cdd:pfam05483  623 KGSAENKQLNAYEIKVNKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEVEKAKAIAD 685
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1572-1815 1.03e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 1.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1572 QQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQ 1651
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1652 DLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIklslrerGRELTTQRQLMQERAEEGKGpskaqrgsLEHMKLIL 1731
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDA-------VRRLQYLKYLAPARREQAEE--------LRADLAEL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1732 RDKEKEVECQQEhihELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQgelkEQSLQSQLDEAQRA 1811
Cdd:COG4942    163 AALRAELEAERA---ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE----AEELEALIARLEAE 235


                   ....
gi 2217334288 1812 LAQR 1815
Cdd:COG4942    236 AAAA 239
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1243-1694 1.08e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.26  E-value: 1.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1243 SALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEE----KSKWEGKQNSLE---SEL 1315
Cdd:TIGR04523  197 LKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQlnqlKDEQNKIKKQLSekqKEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1316 MELHETMASLQSRLR--RAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALK-LKN 1392
Cdd:TIGR04523  277 EQNNKKIKELEKQLNqlKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTnSES 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1393 EEVESERERAQALQEQGELKVAQGKALQENLALLTQTlAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEV 1472
Cdd:TIGR04523  357 ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQI-NDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETI 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1473 DLQQEQIQELEKCRSVLEhlpMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL 1552
Cdd:TIGR04523  436 IKNNSEIKDLTNQDSVKE---LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKV 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1553 VTLECLALELEENHHKMECQ----QKLIKELEGQRETQRVALTHltLDLEERSQELQAQSSQIHD----LESHSTVLARE 1624
Cdd:TIGR04523  513 KDLTKKISSLKEKIEKLESEkkekESKISDLEDELNKDDFELKK--ENLEKEIDEKNKEIEELKQtqksLKKKQEEKQEL 590

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1625 LQERDQEVKSQREQIEELQRQKEHLTQDLERRDQElmlqKERIQVLEDQRTRQTKILEEDLEQIKLSLRE 1694
Cdd:TIGR04523  591 IDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKE----NEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 814-935 1.21e-06

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 53.93  E-value: 1.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  814 ELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQ--QELAKALESLEREKMELEMRL 891
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEAEKELIEeiQELKEELEQRYGKIPELEKEL 494

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2217334288  892 KEQQTEMEAIQAQREEERTQAESA----------LCQMqLETEKERVSLLETLL 935
Cdd:COG0542    495 AELEEELAELAPLLREEVTEEDIAevvsrwtgipVGKL-LEGEREKLLNLEEEL 547
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 832-1115 1.33e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 53.97  E-value: 1.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  832 QLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREK---MELEMRLKEQQTEMeAIQAQREEE 908
Cdd:pfam17380  273 QLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARqaeMDRQAAIYAEQERM-AMERERELE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  909 RTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKV---QKLKEQETTGILQTQLQEAQRELKEAAR 985
Cdd:pfam17380  352 RIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAarkVKILEEERQRKIQQQKVEMEQIRAEQEE 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  986 QHRDDLAALQEESSSLL----QDKMDLQKQVEDLKSQ------------------LVAQDDSQRLVEQEVQEKLRETQEY 1043
Cdd:pfam17380  432 ARQREVRRLEEERAREMervrLEEQERQQQVERLRQQeeerkrkklelekekrdrKRAEEQRRKILEKELEERKQAMIEE 511

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217334288 1044 NRIQKELEREKASLTLSLMEKEQRLLVLQE-ADSIRQQELSALRQDMQEAQGEQKELSA---QMELLRQEVKEKEA 1115
Cdd:pfam17380  512 ERKRKLLEKEMEERQKAIYEEERRREAEEErRKQQEMEERRRIQEQMRKATEERSRLEAmerEREMMRQIVESEKA 587
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1391-1903 1.69e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.49  E-value: 1.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1391 KNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQ 1470
Cdd:TIGR04523   31 QDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1471 EVDLQQEQIQELEKCRSVLEHlpmAVQEREQKLTVQREQIRELEKDRE---TQRNVLEHQLLELEKKDQMIESQRGQVQ- 1546
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEK---QKKENKKNIDKFLTEIKKKEKELEklnNKYNDLKKQKEELENELNLLEKEKLNIQk 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1547 ---DLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLAR 1623
Cdd:TIGR04523  188 nidKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1624 ELQERDQEVKSQREQIEELQRQKEHLTQDLERrdqelmLQKERIQVLedqrtrqTKILEEDLEQIKLSLRERGRELTTQR 1703
Cdd:TIGR04523  268 QLSEKQKELEQNNKKIKELEKQLNQLKSEISD------LNNQKEQDW-------NKELKSELKNQEKKLEEIQNQISQNN 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1704 QLMQERAEEGKGPSKAQRGSLEHMKLI---LRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEI 1780
Cdd:TIGR04523  335 KIISQLNEQISQLKKELTNSESENSEKqreLEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQI 414

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1781 VVLQQQLQE-AREQGELKEQ--SLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKER 1857
Cdd:TIGR04523  415 KKLQQEKELlEKEIERLKETiiKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK 494

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 2217334288 1858 HGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKAL 1903
Cdd:TIGR04523  495 EKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKI 540
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 666-900 1.84e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 1.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  666 AQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRL 745
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  746 QAVERDRQDLAEQLQGLSSAKELLESS---LFEAQQQNSVIEVTKGQLevqIQTVTQAKEVIQGEVRCLKLELDTERSQA 822
Cdd:COG4942     93 AELRAELEAQKEELAELLRALYRLGRQpplALLLSPEDFLDAVRRLQY---LKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217334288  823 EQERDAAARQLAQAEQEgKTALEQQKAAHEKEVNQLREKwekerswhQQELAKALESLEREKMELEMRLKEQQTEMEA 900
Cdd:COG4942    170 EAERAELEALLAELEEE-RAALEALKAERQKLLARLEKE--------LAELAAELAELQQEAEELEALIARLEAEAAA 238
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1575-1898 2.32e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 2.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1575 LIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLEshstvlaRELQERDQEVKSQREQIEELQRQKEHLTQDLE 1654
Cdd:TIGR02169  196 KRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALE-------RQKEAIERQLASLEEELEKLTEEISELEKRLE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1655 RRDQELMLQKERIQVL--EDQRTRQTKI--LEEDLEQIKLSLRERGRELttqrQLMQERAEEGKGPSKAQRGSLEHMKLI 1730
Cdd:TIGR02169  269 EIEQLLEELNKKIKDLgeEEQLRVKEKIgeLEAEIASLERSIAEKEREL----EDAEERLAKLEAEIDKLLAEIEELERE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1731 LRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIvvlqQQLQEAREQGELKEQSLQSQLDEAQR 1810
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL----EKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1811 ALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLG 1890
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500


                   ....*...
gi 2217334288 1891 DLRAESRE 1898
Cdd:TIGR02169  501 ASEERVRG 508
PTZ00121 PTZ00121
MAEBL; Provisional
 1624-2220 2.41e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 2.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1624 ELQERDQEVKSQRE--QIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKileEDLEQIKLSLRERGRELTT 1701
Cdd:PTZ00121  1179 EAARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAK---KDAEEAKKAEEERNNEEIR 1255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1702 QRQ--LMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQlqglhRKVGETSLLLSQREQE 1779
Cdd:PTZ00121  1256 KFEeaRMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEA-----KKADEAKKKAEEAKKK 1330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1780 IVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKE--KADALQGALEQAHMT---L 1854
Cdd:PTZ00121  1331 ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEkkKADEAKKKAEEDKKKadeL 1410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1855 KERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEV-----ETRALQDSWL 1929
Cdd:PTZ00121  1411 KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAkkkaeEAKKADEAKK 1490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1930 QAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQ 2009
Cdd:PTZ00121  1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK 1570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2010 AHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQE--------REQLLEKSLAQRVQENMIQEKQNLG 2081
Cdd:PTZ00121  1571 KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEakikaeelKKAEEEKKKVEQLKKKEAEEKKKAE 1650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2082 QEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPR----LQRELERLQA 2157
Cdd:PTZ00121  1651 ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKkaeeLKKAEEENKI 1730

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 2158 ALRQTEAREIEWREKAQDLAL------SLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRR 2220
Cdd:PTZ00121  1731 KAEEAKKEAEEDKKKAEEAKKdeeekkKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
666-999 2.96e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 52.21  E-value: 2.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  666 AQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRL 745
Cdd:COG4372     38 FELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEEL 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  746 QAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIqgevrclkleLDTERSQAEQE 825
Cdd:COG4372    118 EELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQAL----------SEAEAEQALDE 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  826 RDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQR 905
Cdd:COG4372    188 LLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAI 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  906 EEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAAR 985
Cdd:COG4372    268 LVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLL 347

                          330
                   ....*....|....
gi 2217334288  986 QHRDDLAALQEESS 999
Cdd:COG4372    348 VGLLDNDVLELLSK 361
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 970-1169 3.39e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  970 QTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKE 1049
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1050 LEREKASL--TLSLMEKEQRLLVLQEADSIRQ---------QELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADfL 1118
Cdd:COG4942    102 QKEELAELlrALYRLGRQPPLALLLSPEDFLDavrrlqylkYLAPARREQAEELRADLAELAALRAELEAERAELEAL-L 180

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2217334288 1119 AQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAE 1169
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1636-1991 3.40e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.75  E-value: 3.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1636 REQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEedleqIKLSLRERGRELTTQRQlmqERAEEGKG 1715
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKE-----LKAELRELELALLVLRL---EELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1716 PSKAQRGSLEHMKLILRDKEKEVECQ-QEHIHELQELKDQLEQQLQGLHRKVGETSLLlSQREQEIVVLQQQLQEAREQG 1794
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKlEELRLEVSELEEEIEELQKELYALANEISRL-EQQKQILRERLANLERQLEEL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1795 ELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEE 1874
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1875 LAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQA-QEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSR 1953
Cdd:TIGR02168  402 IERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAAE 481

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 2217334288 1954 HQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELS 1991
Cdd:TIGR02168  482 RELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLS 519
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 12-580 3.64e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.75  E-value: 3.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288   12 KPQSLQLVLEEQVLALQQQMAENQAASWRKLKNSQEAQQRQATL-VRKLQAKVLQYRSWCQELEKRLEATGGPIPQRWEN 90
Cdd:TIGR02168  350 KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELqIASLNNEIERLEARLERLEDRRERLQQEIEELLKK 429

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288   91 VEEPNLDELLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQMEQEFFKGY- 169
Cdd:TIGR02168  430 LEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVk 509

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  170 --------LKGEHGRLLSL-----------------------------WREVVTF-------RRHFLEMKSATDRDLMEL 205
Cdd:TIGR02168  510 allknqsgLSGILGVLSELisvdegyeaaieaalggrlqavvvenlnaAKKAIAFlkqnelgRVTFLPLDSIKGTEIQGN 589

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  206 KAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDG----REPAQLLLLLAKTQELEK----------------------- 258
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGvlvvDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktn 669

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  259 -EAHERSQELIQLKSQgdleKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEE 337
Cdd:TIGR02168  670 sSILERRREIEELEEK----IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  338 KLSLQQVIKDITQVMVEEgdNIAQGSGHENSLELdssifsqfdyQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVN 417
Cdd:TIGR02168  746 EERIAQLSKELTELEAEI--EELEERLEEAEEEL----------AEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  418 LLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQ 497
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLR 893

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  498 LQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSH-LEGELLRQEQTEVTAALARAEQS 576
Cdd:TIGR02168  894 SELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYsLTLEEAEALENKIEDDEEEARRR 973


                   ....
gi 2217334288  577 IAEL 580
Cdd:TIGR02168  974 LKRL 977
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1396-2226 3.66e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.76  E-value: 3.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1396 ESERERAQALQEQGELKvaqgkalqENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQ 1475
Cdd:TIGR02169  167 EFDRKKEKALEELEEVE--------ENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1476 QEQIQ-ELEKCRSVLEHLPMAVQEREQKLTVQREQIREL----EKDRETQRNVLEHQLLELEKKdqmIESQRGQVQDLKK 1550
Cdd:TIGR02169  239 KEAIErQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkiKDLGEEEQLRVKEKIGELEAE---IASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1551 QLVTLECLALELEENHHKMECQqklIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQ 1630
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAE---IEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1631 EVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRqtkiLEEDLEQIKLSLRERGRELTTQRQLMQERA 1710
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE----LEEEKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1711 EEgkgpskaqrgslehmkliLRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGE---TSLLLSQREQEIVVLQQQL 1787
Cdd:TIGR02169  469 QE------------------LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGgraVEEVLKASIQGVHGTVAQL 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1788 QEAREQGELK-EQSLQSQLD--------EAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAhMTLKE-- 1856
Cdd:TIGR02169  531 GSVGERYATAiEVAAGNRLNnvvveddaVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFA-VDLVEfd 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1857 -----------RHGELQDHKEQARR---------LEEEL----------AVEGRRVQALEEVLGDLRAESREQEKALLAL 1906
Cdd:TIGR02169  610 pkyepafkyvfGDTLVVEDIEAARRlmgkyrmvtLEGELfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRE 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1907 QQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLE 1986
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEE 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1987 QAELSRSLEASTATLQASLDacQAHSRQLEEALRIQEGEIQDQDLRYQEdvqqlqqalaqRDEELRHQQEREQLLEKSLA 2066
Cdd:TIGR02169  770 LEEDLHKLEEALNDLEARLS--HSRIPEIQAELSKLEEEVSRIEARLRE-----------IEQKLNRLTLEKEYLEKEIQ 836

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2067 QRVQENMIQEKQNLGQEREEEEIRGlhqSVRELQLTLAQKEQEILELRE-----TQQRNNLEAlPHSHKTSPMEEQSLKL 2141
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIEKEIENLNG---KKEELEEELEELEAALRDLESrlgdlKKERDELEA-QLRELERKIEELEAQI 912

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2142 DSLEPRLQRELERLQAALRQTEAREIEWRE---------KAQDLALSLAQTKASVSSLQEVAMflqASVLERDSEQQRLq 2212
Cdd:TIGR02169  913 EKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelSLEDVQAELQRVEEEIRALEPVNM---LAIQEYEEVLKRL- 988

                          890
                   ....*....|....
gi 2217334288 2213 DELELTRRALEKER 2226
Cdd:TIGR02169  989 DELKEKRAKLEEER 1002
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 524-1044 4.01e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 52.36  E-value: 4.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  524 LQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENtLKTEVADLRAAAVKLSA 603
Cdd:TIGR00606  575 LEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQD-EESDLERLKEEIEKSSK 653

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  604 LNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLR 683
Cdd:TIGR00606  654 QRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAP 733

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  684 DIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEAL------VREKAALEVRLQAVERDRQDLAE 757
Cdd:TIGR00606  734 GRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAkvcltdVTIMERFQMELKDVERKIAQQAA 813

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  758 QLQGLSSAKELLESSLFEAQQQNSVIEVTKgqlevQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAE 837
Cdd:TIGR00606  814 KLQGSDLDRTVQQVNQEKQEKQHELDTVVS-----KIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEE 888

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  838 QEGKTALEQQKAAHE-KEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESAL 916
Cdd:TIGR00606  889 QLVELSTEVQSLIREiKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGK 968

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  917 CQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQK-----LKEQETTGILQTQLQEAQRELKEAARQHRDDL 991
Cdd:TIGR00606  969 DDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKiqerwLQDNLTLRKRENELKEVEEELKQHLKEMGQMQ 1048

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2217334288  992 AALQEESSSLLQDKMDLQKQVEDLK-SQLVAQDDSQRLVEQEVQEKLRETQEYN 1044
Cdd:TIGR00606 1049 VLQMKQEHQKLEENIDLIKRNHVLAlGRQKGYEKEIKHFKKELREPQFRDAEEK 1102
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1245-1905 4.25e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 4.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1245 LHKLHQDLWKTQQTRDVLR------DQVQKLEERLTDTEAEKSQVhtELQDLQRQLSQNQEEKSKWEGKQNSLESELMEL 1318
Cdd:COG4913    237 LERAHEALEDAREQIELLEpirelaERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1319 HETMASLQSRLRRAELQRMEAQGERellqaaKENLTAQVEHLQAavvEARAQASAAGILEEDLRTARSALKLKNEEVESE 1398
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDR------LEQLEREIERLER---ELEERERRRARLEALLAALGLPLPASAEEFAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1399 RERAQALQEQGElkvAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQR----EMQKAALELLSLDLKKRNQEVDL 1474
Cdd:COG4913    386 RAEAAALLEALE---EELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEAELPF 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1475 QQEQIQELEKCRS-------VL-----------EHLPMA---VQEREQKLTVQREQIRELEKDRETQRnVLEHQLLElek 1533
Cdd:COG4913    463 VGELIEVRPEEERwrgaierVLggfaltllvppEHYAAAlrwVNRLHLRGRLVYERVRTGLPDPERPR-LDPDSLAG--- 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1534 kdqMIESQRGQVQDLKKQLVtleclalELEENHHKMECQQKLikelegqRETQRvALThltldleersqeLQAQSSQIHD 1613
Cdd:COG4913    539 ---KLDFKPHPFRAWLEAEL-------GRRFDYVCVDSPEEL-------RRHPR-AIT------------RAGQVKGNGT 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1614 LESHSTvlARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLR 1693
Cdd:COG4913    589 RHEKDD--RRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASA 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1694 ERGRelttqRQLMQERAEegkgpskaqrgslehmkliLRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETslll 1773
Cdd:COG4913    667 EREI-----AELEAELER-------------------LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRL---- 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1774 sqrEQEIVVLQQQLQEAREQ----GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQ 1849
Cdd:COG4913    719 ---EKELEQAEEELDELQDRleaaEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217334288 1850 AHMTLKERHGELQDHKEQARRLEEELA-VEGRRVQALEEVLGDLRAESREQEKALLA 1905
Cdd:COG4913    796 FNREWPAETADLDADLESLPEYLALLDrLEEDGLPEYEERFKELLNENSIEFVADLL 852
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1239-1660 4.39e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 4.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1239 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEekskwegkqnslesELMEL 1318
Cdd:PRK02224   324 EELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRRE--------------EIEEL 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1319 HETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAavvearaqasaagileeDLRTARSALklkneevese 1398
Cdd:PRK02224   390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEA-----------------TLRTARERV---------- 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1399 rERAQALQEQGELKVAqGKALQEnlALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSlDLKKRNQEVDLQQEQ 1478
Cdd:PRK02224   443 -EEAEALLEAGKCPEC-GQPVEG--SPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEER 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1479 IQELEKcrsVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLvtlecl 1558
Cdd:PRK02224   518 REDLEE---LIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERI------ 588

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1559 aleleENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLEShstvlarELQE-RDQEVKSQRE 1637
Cdd:PRK02224   589 -----ESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEA-------EFDEaRIEEAREDKE 656

                          410       420
                   ....*....|....*....|...
gi 2217334288 1638 QIEELQRQKEHLTQDLERRDQEL 1660
Cdd:PRK02224   657 RAEEYLEQVEEKLDELREERDDL 679
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 418-1120 5.35e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.90  E-value: 5.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  418 LLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQ 497
Cdd:pfam02463  304 KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  498 LQGDSAQGQKEEQQEELHLAVRE-------RERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAAL 570
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEaqlllelARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKD 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  571 ARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEA 650
Cdd:pfam02463  464 ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKV 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  651 EKRRE--ALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQ-EAKRQEEVLARA 727
Cdd:pfam02463  544 AISTAviVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKaTLEADEDDKRAK 623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  728 VQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGE 807
Cdd:pfam02463  624 VVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKK 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  808 VRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQK--AAHEKEVNQLREKWEKERSWHQQELAKALESLEREKM 885
Cdd:pfam02463  704 KEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKidEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKT 783

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  886 ELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQET 965
Cdd:pfam02463  784 EKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEI 863

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  966 TGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEvQEKLRETQEYNR 1045
Cdd:pfam02463  864 TKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEIL-LKYEEEPEELLL 942

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1046 IQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQ 1120
Cdd:pfam02463  943 EEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 570-1102 5.64e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.94  E-value: 5.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  570 LARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAE 649
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSN 205

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  650 AEKRREalweKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSEsrhqqeaATTQLEQLHQEAKRQEEVLARAVQ 729
Cdd:TIGR04523  206 LKKKIQ----KNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISN-------TQTQLNQLKDEQNKIKKQLSEKQK 274

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  730 EKEALVREKAALEVRLQAVERDRQDLAEQLQglssaKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQgevr 809
Cdd:TIGR04523  275 ELEQNNKKIKELEKQLNQLKSEISDLNNQKE-----QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQIS---- 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  810 clklELDTERSQAEQERDAAARQLAQAEQEGKTaLEQQKAAHEKEVNQLREKwekerswhQQELAKALESLEREKMELEM 889
Cdd:TIGR04523  346 ----QLKKELTNSESENSEKQRELEEKQNEIEK-LKKENQSYKQEIKNLESQ--------INDLESKIQNQEKLNQQKDE 412

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  890 RLKEQQTEMEAIQaqREEERTQAESALCQMQLETEKERVSLLETLLqtqKELADASQQLERLRQDMKVQKLKEQETTGIL 969
Cdd:TIGR04523  413 QIKKLQQEKELLE--KEIERLKETIIKNNSEIKDLTNQDSVKELII---KNLDNTRESLETQLKVLSRSINKIKQNLEQK 487

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  970 QTQLQEAQRELKEAARQHRD---DLAALQEESSSLLQ-------DKMDLQKQVEDLKSQLVAQDD--SQRLVEQEVQEKL 1037
Cdd:TIGR04523  488 QKELKSKEKELKKLNEEKKEleeKVKDLTKKISSLKEkieklesEKKEKESKISDLEDELNKDDFelKKENLEKEIDEKN 567

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1038 RETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 1102
Cdd:TIGR04523  568 KEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSI 632
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
616-1045 5.82e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 5.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  616 NQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREA--LWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQ 693
Cdd:COG4717     87 EEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLlpLYQELEALEAELAELPERLEELEERLEELRELEEELE 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  694 KKLSESRHQQEAATTQLEQL----HQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELL 769
Cdd:COG4717    167 ELEAELAELQEELEELLEQLslatEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLK 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  770 E-SSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQ---AEQEGKTALE 845
Cdd:COG4717    247 EaRLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALeelEEEELEELLA 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  846 QQKAAHEKEVNQLREKWEKERSWhqQELAKALESLEREkMELEMRLKEQQTEMEAIQAQREEERTQAesalcqmqLETEK 925
Cdd:COG4717    327 ALGLPPDLSPEELLELLDRIEEL--QELLREAEELEEE-LQLEELEQEIAALLAEAGVEDEEELRAA--------LEQAE 395

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  926 ERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTgiLQTQLQEAQRELKEAARQHRDDLAALQE-ESSSLLQD 1004
Cdd:COG4717    396 EYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEE--LEEELEELEEELEELREELAELEAELEQlEEDGELAE 473

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 2217334288 1005 KMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNR 1045
Cdd:COG4717    474 LLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
453-996 5.95e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 5.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  453 DLQGEVDSLSKERELLQKAREElRQQLEVLEQEAWRLRRVNVELQ-LQGDSAQGQKEEQQEELHLAVRERERLQEMLMGL 531
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQ-IELLEPIRELAERYAAARERLAeLEYLRAALRLWFAQRRLELLEAELEELRAELARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  532 EAKQSESLSELITLREALEsshlegELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAavkLSALNEALALD 611
Cdd:COG4913    308 EAELERLEARLDALREELD------ELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEAL---LAALGLPLPAS 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  612 KVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQL----QKAEEAGAELQADLRDIQE 687
Cdd:COG4913    379 AEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEA 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  688 E----KEEIQKKLSESR--------------------HQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEV 743
Cdd:COG4913    459 ElpfvGELIEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAG 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  744 RLQAVERDRQDLAEQLQGLSSAKELLESslfEAQQQNSVIEVTK-GQL-------EVQIQTVTQAKEVIQGEVRCLKLEL 815
Cdd:COG4913    539 KLDFKPHPFRAWLEAELGRRFDYVCVDS---PEELRRHPRAITRaGQVkgngtrhEKDDRRRIRSRYVLGFDNRAKLAAL 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  816 DTERSQAEQERDAAARQLAQAEQEGKTALEQQKA---------------AHEKEVNQLREKWEKERSWHQ--QELAKALE 878
Cdd:COG4913    616 EAELAELEEELAEAEERLEALEAELDALQERREAlqrlaeyswdeidvaSAEREIAELEAELERLDASSDdlAALEEQLE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  879 SLEREKMELEMRLKEQQTEMEAIQAQR---EEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDM 955
Cdd:COG4913    696 ELEAELEELEEELDELKGEIGRLEKELeqaEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERI 775

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 2217334288  956 KVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQE 996
Cdd:COG4913    776 DALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPE 816
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1262-1856 6.09e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.56  E-value: 6.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1262 LRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQG 1341
Cdd:TIGR04523  122 LEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLEL 201

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1342 ERELLQAAKEN---LTAQVEHLQAAVVEaraqasaagiLEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKA 1418
Cdd:TIGR04523  202 LLSNLKKKIQKnksLESQISELKKQNNQ----------LKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSE 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1419 LQENLALLTQTLAEREEEVETLRGQIQELEKQREmqkaalELLSLDLKKrnqEVDLQQEQIQELEKcrsvlehlpmAVQE 1498
Cdd:TIGR04523  272 KQKELEQNNKKIKELEKQLNQLKSEISDLNNQKE------QDWNKELKS---ELKNQEKKLEEIQN----------QISQ 332

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1499 REQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEEnhhKMECQQKLIKE 1578
Cdd:TIGR04523  333 NNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLES---KIQNQEKLNQQ 409

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1579 LEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQ 1658
Cdd:TIGR04523  410 KDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1659 ELMLQKERIQVLedqrTRQTKILEEDLEQIKlslRERGRELTTQRQLMQERAEegkgpskaqrgslehMKLILRDKEKEV 1738
Cdd:TIGR04523  490 ELKSKEKELKKL----NEEKKELEEKVKDLT---KKISSLKEKIEKLESEKKE---------------KESKISDLEDEL 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1739 ECQQEHIHelqelKDQLEQQLQGLHRKVGEtsllLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQE 1818
Cdd:TIGR04523  548 NKDDFELK-----KENLEKEIDEKNKEIEE----LKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 2217334288 1819 LEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKE 1856
Cdd:TIGR04523  619 LEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1250-1584 8.44e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 50.67  E-value: 8.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1250 QDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRL 1329
Cdd:COG4372     31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1330 RRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQAsaagileEDLRTARSALKLKNEEVESERERAQALQEQG 1409
Cdd:COG4372    111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEEL-------KELEEQLESLQEELAALEQELQALSEAEAEQ 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1410 ELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVL 1489
Cdd:COG4372    184 ALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEEL 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1490 EHLPMAVQEREQ-KLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHK 1568
Cdd:COG4372    264 ELAILVEKDTEEeELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLL 343

                          330
                   ....*....|....*.
gi 2217334288 1569 MECQQKLIKELEGQRE 1584
Cdd:COG4372    344 QLLLVGLLDNDVLELL 359
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 936-1189 1.16e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 1.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  936 QTQKELADASQQLERLRQDMKVQKLKEQEttgiLQTQLQEAQRELKEAARQhrddLAALQEESSSLLQDKMDLQKQVEDL 1015
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKA----LLKQLAALERRIAALARR----IRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1016 KSQLVAQddsqrlvEQEVQEKLRETQEYNRIQKELEREKASltlSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGE 1095
Cdd:COG4942     96 RAELEAQ-------KEELAELLRALYRLGRQPPLALLLSPE---DFLDAVRRLQYLKYLAPARREQAEELRADLAELAAL 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1096 QKELSAQMELLRQEVKEKEAdflaQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQ 1175
Cdd:COG4942    166 RAELEAERAELEALLAELEE----ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241

                          250
                   ....*....|....
gi 2217334288 1176 AQAQAQLASLYSAL 1189
Cdd:COG4942    242 RTPAAGFAALKGKL 255
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 601-831 1.36e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  601 LSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQA 680
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  681 DLRDIQEEKEEIQKKLSE--------SRHQQEAATTQLEQLHQEAKRQE--EVLARAVQEK-EALVREKAALEVRLQAVE 749
Cdd:COG4942     91 EIAELRAELEAQKEELAEllralyrlGRQPPLALLLSPEDFLDAVRRLQylKYLAPARREQaEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  750 RDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAA 829
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250


                   ..
gi 2217334288  830 AR 831
Cdd:COG4942    251 LK 252
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1835-2251 1.37e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.72  E-value: 1.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1835 RVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEElavegrrVQALEEVLGDLRAESREQekallalqqqcaeqa 1914
Cdd:COG3096    351 RYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEE-------VDSLKSQLADYQQALDVQ--------------- 408

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1915 qehevETRALQdsWLQAQAVLkERDQELEALRAESqssrhqeeaararaealQEALGKAHAALQGKEQhlleqaelsrSL 1994
Cdd:COG3096    409 -----QTRAIQ--YQQAVQAL-EKARALCGLPDLT-----------------PENAEDYLAAFRAKEQ----------QA 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1995 EASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDlryQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMI 2074
Cdd:COG3096    454 TEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVE---RSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQ 530

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2075 QEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELrETQQRNNLEALphshktspmeeqslkldslePRLQRELER 2154
Cdd:COG3096    531 QQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEEL-EEQAAEAVEQR--------------------SELRQQLEQ 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2155 LQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQaSVLERDSEQQRLQDELELTRRALEK--ERLHSPGA 2232
Cdd:COG3096    590 LRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQ-QLLEREREATVERDELAARKQALESqiERLSQPGG 668

                          410       420
                   ....*....|....*....|.
gi 2217334288 2233 TSTAELGSRGEQ--GVQLGEV 2251
Cdd:COG3096    669 AEDPRLLALAERlgGVLLSEI 689
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 369-1114 1.65e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.43  E-value: 1.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  369 LELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQdlrQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQ----KLTGER 444
Cdd:TIGR00606  377 LELDGFERGPFSERQIKNFHTLVIERQEDEAKTAA---QLCADLQSKERLKQEQADEIRDEKKGLGRTIElkkeILEKKQ 453

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  445 DTLAGQTVDLQGEVDSLSKERELLQKAREELRQqLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERL 524
Cdd:TIGR00606  454 EELKFVIKELQQLEGSSDRILELDQELRKAERE-LSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTT 532

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  525 QEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTaalaraEQSIAELSSSENTLKTEVADLRAAAVKLSAL 604
Cdd:TIGR00606  533 TRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQL------EDWLHSKSKEINQTRDRLAKLNKELASLEQN 606

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  605 NEALALDKVGLNQQLLQLEEENQSVCSrMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRD 684
Cdd:TIGR00606  607 KNHINNELESKEEQLSSYEDKLFDVCG-SQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQR 685

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  685 IQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEevlaravQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSS 764
Cdd:TIGR00606  686 VFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKE-------KRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNR 758

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  765 AKELLESSLFEAQQQNSVIeVTKGQLEVQIQTVTQAKEVIQGEVRclklelDTERSQAEQERDAAARQLAQAEQEGKTAL 844
Cdd:TIGR00606  759 DIQRLKNDIEEQETLLGTI-MPEEESAKVCLTDVTIMERFQMELK------DVERKIAQQAAKLQGSDLDRTVQQVNQEK 831

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  845 EQQKAAHEKEVNQLRE--KWEKERSWHQQELAKALESLEREKMELEMRLKEQQtemeAIQAQREEERTQAESalCQMQLE 922
Cdd:TIGR00606  832 QEKQHELDTVVSKIELnrKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQ----QFEEQLVELSTEVQS--LIREIK 905

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  923 TEKERVSLLETLL---QTQKELADASQQLERLRQDMKVQKLKEQ--ETTGILQTQLQEAQRELKEAARQHRDDLAALQEE 997
Cdd:TIGR00606  906 DAKEQDSPLETFLekdQQEKEELISSKETSNKKAQDKVNDIKEKvkNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQ 985

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  998 ssslLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIqKELEREKASLTLSLmeKEQRLLVLQEADSI 1077
Cdd:TIGR00606  986 ----LEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENEL-KEVEEELKQHLKEM--GQMQVLQMKQEHQK 1058

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 2217334288 1078 RQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKE 1114
Cdd:TIGR00606 1059 LEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQ 1095
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1237-1873 1.69e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 50.35  E-value: 1.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1237 SAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTdTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELM 1316
Cdd:TIGR00618  220 RKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLK-KQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAH 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1317 ELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVE 1396
Cdd:TIGR00618  299 IKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLT 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1397 SERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQ 1476
Cdd:TIGR00618  379 QHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEK 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1477 EQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLE 1556
Cdd:TIGR00618  459 IHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1557 CLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTldleersQELQAQSSQIHDLESHSTVLARELQERDQEVKSQR 1636
Cdd:TIGR00618  539 QLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILT-------QCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLA 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1637 EQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGP 1716
Cdd:TIGR00618  612 CEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQ 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1717 SKAQRGSLEHMKLILRDKEKEVECQQEHIHELQE----LKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQE--- 1789
Cdd:TIGR00618  692 LTYWKEMLAQCQTLLRELETHIEEYDREFNEIENasssLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEevt 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1790 AREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD-ALQGALEQAHMTLKERHGELQDHKEQA 1868
Cdd:TIGR00618  772 AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCeTLVQEEEQFLSRLEEKSATLGEITHQL 851


                   ....*
gi 2217334288 1869 RRLEE 1873
Cdd:TIGR00618  852 LKYEE 856
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 875-1739 1.75e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.43  E-value: 1.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  875 KALESLEREKMELEMRLKEQQTEMEAIQAQRE---EERTQAESALCQMQLETE--KERVSLLETLLQTQKELADASQQLE 949
Cdd:TIGR00606  186 KALETLRQVRQTQGQKVQEHQMELKYLKQYKEkacEIRDQITSKEAQLESSREivKSYENELDPLKNRLKEIEHNLSKIM 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  950 RLRQDMKVQKLKEQETTGiLQTQLQEAQRELKEAARQHRDDLAAL-QEESSSLLQDKMDLQKQVEDL--KSQLVAQDDSQ 1026
Cdd:TIGR00606  266 KLDNEIKALKSRKKQMEK-DNSELELKMEKVFQGTDEQLNDLYHNhQRTVREKERELVDCQRELEKLnkERRLLNQEKTE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1027 RLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADS-----IRQQELSALRQDMQEAQGEQKELSA 1101
Cdd:TIGR00606  345 LLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNfhtlvIERQEDEAKTAAQLCADLQSKERLK 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1102 QMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRA-SLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQA 1180
Cdd:TIGR00606  425 QEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELqQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVK 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1181 QLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASAL---HKLHQDLWKTQQ 1257
Cdd:TIGR00606  505 SLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFpnkKQLEDWLHSKSK 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1258 TRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQnSLESELMELHETMAslQSRLRRAELQRM 1337
Cdd:TIGR00606  585 EINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQ-DEESDLERLKEEIE--KSSKQRAMLAGA 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1338 EAQGERELLQAAKEN-----LTAQVEHLQAAVVEARAQASAAGILEED-LRTARSALKLKNEEVESERERAQALQEQGEL 1411
Cdd:TIGR00606  662 TAVYSQFITQLTDENqsccpVCQRVFQTEAELQEFISDLQSKLRLAPDkLKSTESELKKKEKRRDEMLGLAPGRQSIIDL 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1412 KVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAAL------ELLSLDLKKRNQEVDLQQEQIQELEKC 1485
Cdd:TIGR00606  742 KEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLtdvtimERFQMELKDVERKIAQQAAKLQGSDLD 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1486 RSVLEhLPMAVQEREQKL---TVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALEL 1562
Cdd:TIGR00606  822 RTVQQ-VNQEKQEKQHELdtvVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSL 900

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1563 EENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQ-ELQAQSSQIHDLESHSTVLARELQERDQEVKSQRE---- 1637
Cdd:TIGR00606  901 IREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQdKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKEteln 980

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1638 ----QIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRqtKILEEDLEQIKLSLRERGRELtTQRQLMQERAEEG 1713
Cdd:TIGR00606  981 tvnaQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTL--RKRENELKEVEEELKQHLKEM-GQMQVLQMKQEHQ 1057

                          890       900
                   ....*....|....*....|....*.
gi 2217334288 1714 KGPSKAQRGSLEHMKLILRDKEKEVE 1739
Cdd:TIGR00606 1058 KLEENIDLIKRNHVLALGRQKGYEKE 1083
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1361-1677 2.26e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 49.74  E-value: 2.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1361 QAAVVEARAQASAAGILEEDLRTARSALKLKNEE----VESERERAQALQEQGELKVAQGK-ALQENLALLTQTLAEREE 1435
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERrrklEEAEKARQAEMDRQAAIYAEQERmAMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1436 EVETLRGQ--IQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIREL 1513
Cdd:pfam17380  361 ELERIRQEeiAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRL 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1514 EKDRETQrnvLEHQLLELEKKDQMIESQRGQVQDLKKQlvtlecLALELEENHHKMECQQKLIKELEGQRETQRVALTHl 1593
Cdd:pfam17380  441 EEERARE---MERVRLEEQERQQQVERLRQQEEERKRK------KLELEKEKRDRKRAEEQRRKILEKELEERKQAMIE- 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1594 tldlEERSQELQAQssqihDLESHSTVLARELQERDQEVKSQREQ-IEELQRQKEHLTQDLERRDQELMLQKER---IQV 1669
Cdd:pfam17380  511 ----EERKRKLLEK-----EMEERQKAIYEEERRREAEEERRKQQeMEERRRIQEQMRKATEERSRLEAMERERemmRQI 581


                   ....*...
gi 2217334288 1670 LEDQRTRQ 1677
Cdd:pfam17380  582 VESEKARA 589
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 1266-1551 2.68e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 49.64  E-value: 2.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1266 VQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELhetmasLQSRLRRAELQRMEAQGERel 1345
Cdd:pfam05667  228 SQGLASRLTPEEYRKRKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAEL------LSSFSGSSTTDTGLTKGSR-- 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1346 lQAAKENLTAQVEHLQAAVVEARAQASaagilEEDLRTARSalklknEEVESERERAQALQEQGElkvaqgkALQENLAL 1425
Cdd:pfam05667  300 -FTHTEKLQFTNEAPAATSSPPTKVET-----EEELQQQRE------EELEELQEQLEDLESSIQ-------ELEKEIKK 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1426 LTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLD---LKKRNQEVDLQQEQIQEL----EKCRS--VLEHLPMAV 1496
Cdd:pfam05667  361 LESSIKQVEEELEELKEQNEELEKQYKVKKKTLDLLPDAeenIAKLQALVDASAQRLVELagqwEKHRVplIEEYRALKE 440

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1497 QEREQKLTVQReQIRELEKDRETQRNVLEhqllELEKKDQMIESQRGQVQDLKKQ 1551
Cdd:pfam05667  441 AKSNKEDESQR-KLEEIKELREKIKEVAE----EAKQKEELYKQLVAEYERLPKD 490
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 408-1019 2.81e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.84  E-value: 2.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  408 QLAGCQEAVNLLQQQHDQWEEEGKALRQRLqklTGERDTLAGQTVDLQGEVDSLSKERELLQKAR-EELRQQLEVLEQEA 486
Cdd:pfam12128  277 RQEERQETSAELNQLLRTLDDQWKEKRDEL---NGELSAADAAVAKDRSELEALEDQHGAFLDADiETAAADQEQLPSWQ 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  487 WRLRRVNVELQLQGDSAQGQKEEQQEELHLAVrerERLQEMLMGLEAKQsESLSELITLREALESSHLEGelLRQEQTEv 566
Cdd:pfam12128  354 SELENLEERLKALTGKHQDVTAKYNRRRSKIK---EQNNRDIAGIKDKL-AKIREARDRQLAVAEDDLQA--LESELRE- 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  567 taalaRAEQSIAELSSSENTLKTEVADLRaaavklsalneaLALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNA---- 642
Cdd:pfam12128  427 -----QLEAGKLEFNEEEYRLKSRLGELK------------LRLNQATATPELLLQLENFDERIERAREEQEAANAever 489

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  643 LQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEE 722
Cdd:pfam12128  490 LQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEV 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  723 VLARAVQEKEALvrekaALEVRLQAVER-DRQDLAEQLQG-LSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQA 800
Cdd:pfam12128  570 WDGSVGGELNLY-----GVKLDLKRIDVpEWAASEEELRErLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFA 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  801 KeviqgevrclkleldtersQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESL 880
Cdd:pfam12128  645 R-------------------TALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQ 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  881 EREKMELEMRLKEQQTEME--------AIQAQREEERTQAESALCQMQLETEKERVSL---LETLLQTQKELADASQQLE 949
Cdd:pfam12128  706 KEQKREARTEKQAYWQVVEgaldaqlaLLKAAIAARRSGAKAELKALETWYKRDLASLgvdPDVIAKLKREIRTLERKIE 785

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217334288  950 RLRQD-MKVQKLKE--QETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQL 1019
Cdd:pfam12128  786 RIAVRrQEVLRYFDwyQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRL 858
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1240-1952 2.82e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 2.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1240 AVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELH 1319
Cdd:TIGR02169  291 RVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLR 370

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1320 ETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAagiLEEDLRTARSALKLKNEEVESER 1399
Cdd:TIGR02169  371 AELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD---LNAAIAGIEAKINELEEEKEDKA 447

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1400 ERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREM-------QKAALELLSLDLKKRnqeV 1472
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARAseervrgGRAVEEVLKASIQGV---H 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1473 DLQQEQIQELEKCRSVLEhlpMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL 1552
Cdd:TIGR02169  525 GTVAQLGSVGERYATAIE---VAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGF 601

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1553 VTLECLALELEENHHKMECQQKLIKE--LEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQErdq 1630
Cdd:TIGR02169  602 AVDLVEFDPKYEPAFKYVFGDTLVVEdiEAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQR--- 678

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1631 evksQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEdqrtRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERA 1710
Cdd:TIGR02169  679 ----LRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS----RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1711 EEgkgpskaqrgsLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLqglhrkvgetslllsqREQEIVVLQQQLQEA 1790
Cdd:TIGR02169  751 QE-----------IENVKSELKELEARIEELEEDLHKLEEALNDLEARL----------------SHSRIPEIQAELSKL 803

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1791 REQgelkEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKadalqgaleqahmtLKERHGELQDHKEQARR 1870
Cdd:TIGR02169  804 EEE----VSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ--------------IKSIEKEIENLNGKKEE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1871 LEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQehEVETRALQDSWLQAQA-VLKERDQELEALRAES 1949
Cdd:TIGR02169  866 LEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEA--QIEKKRKRLSELKAKLeALEEELSEIEDPKGED 943


                   ...
gi 2217334288 1950 QSS 1952
Cdd:TIGR02169  944 EEI 946
mukB PRK04863
chromosome partition protein MukB;
553-1003 4.19e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 49.19  E-value: 4.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  553 HLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSR 632
Cdd:PRK04863   257 DLFKHLITESTNYVAADYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDH 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  633 MEAAEQARNAlqvdlAEAEKR-REALWEKNTHLEAQLQKAEEAG---AELQADLRDIQEEKEEIQKKLSESRHQQEAATT 708
Cdd:PRK04863   337 LNLVQTALRQ-----QEKIERyQADLEELEERLEEQNEVVEEADeqqEENEARAEAAEEEVDELKSQLADYQQALDVQQT 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  709 QLEQLHQEAKRQEEvlARAVQEKEALVREKAalEVRLQAVERDRQDLAEQlqglssakellessLFEAQQQNSVIEVTKG 788
Cdd:PRK04863   412 RAIQYQQAVQALER--AKQLCGLPDLTADNA--EDWLEEFQAKEQEATEE--------------LLSLEQKLSVAQAAHS 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  789 QLEVQIQTVTQA-----KEVIQGEVRCLKLELDTERSQAEQErDAAARQLAQAEQEgktaLEQQKAAhekevNQLREKWE 863
Cdd:PRK04863   474 QFEQAYQLVRKIagevsRSEAWDVARELLRRLREQRHLAEQL-QQLRMRLSELEQR----LRQQQRA-----ERLLAEFC 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  864 KErswHQQELAKAlESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAEsalcqmQLETEKERVSLLETLLQTqkelad 943
Cdd:PRK04863   544 KR---LGKNLDDE-DELEQLQEELEARLESLSESVSEARERRMALRQQLE------QLQARIQRLAARAPAWLA------ 607

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  944 ASQQLERLRQDMKVQKLKEQETTGILQtQLQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003
Cdd:PRK04863   608 AQDALARLREQSGEEFEDSQDVTEYMQ-QLLERERELTVERDELAARKQALDEEIERLSQ 666
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 924-1586 4.70e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.81  E-value: 4.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  924 EKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003
Cdd:TIGR00618  225 EKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQ 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1004 DKMDLQKQVEDLKSQL------------VAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVL 1071
Cdd:TIGR00618  305 IEQQAQRIHTELQSKMrsrakllmkraaHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTL 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1072 QEADSIRQQELSALRQDMQEAQGEQkelsAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQ 1151
Cdd:TIGR00618  385 QQQKTTLTQKLQSLCKELDILQREQ----ATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIH 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1152 LQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQAL-----GSVCESRPELSGGGDSAPSVWGLEPDQNGARSL 1226
Cdd:TIGR00618  461 LQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEpcplcGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1227 FKrgplltalSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEG 1306
Cdd:TIGR00618  541 ET--------SEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAC 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1307 KQnslESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEED-LRTAR 1385
Cdd:TIGR00618  613 EQ---HALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQkMQSEK 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1386 SALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVEtlrgqiQELEKQREMQKAALELLSLDL 1465
Cdd:TIGR00618  690 EQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALN------QSLKELMHQARTVLKARTEAH 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1466 KKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLL-ELEKKDQMIESQRGQ 1544
Cdd:TIGR00618  764 FNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVqEEEQFLSRLEEKSAT 843

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|..
gi 2217334288 1545 VQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQ 1586
Cdd:TIGR00618  844 LGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIK 885
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1307-1541 5.33e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 5.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1307 KQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAagiLEEDLRTARS 1386
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE---LEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1387 ALKLKNEEVESERERAQALQEQGELKV----AQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLS 1462
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPLALllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1463 LDLKKrnqevdlQQEQIQELEKCRSVLEHLpmaVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQ 1541
Cdd:COG4942    178 ALLAE-------LEEERAALEALKAERQKL---LARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 709-1335 5.72e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.58  E-value: 5.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  709 QLEQLHQEAKRQEEVLARAVQEK-EALVREKaalEVRLQAVERDRQDLAEQLQGLSSAKELLESslfEAQQQNSV----- 782
Cdd:pfam15921  246 QLEALKSESQNKIELLLQQHQDRiEQLISEH---EVEITGLTEKASSARSQANSIQSQLEIIQE---QARNQNSMymrql 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  783 --IEVTKGQLEVQIQtvtQAKEVIQGEVRCLKLEL---DTERSQAEQERDAAARQLAQAEQEGKTALEQqkaAHEKEVNQ 857
Cdd:pfam15921  320 sdLESTVSQLRSELR---EAKRMYEDKIEELEKQLvlaNSELTEARTERDQFSQESGNLDDQLQKLLAD---LHKREKEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  858 LREKWEKERSWhQQELAKALeSLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEK-ERVSLLETLLQ 936
Cdd:pfam15921  394 SLEKEQNKRLW-DRDTGNSI-TIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESlEKVSSLTAQLE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  937 TQKELadasqqLERLRQDMKVQKL---KEQETTGILQTQLQEAQRELKEAARQ-----HRDDLAALQEESSSLLQDKM-D 1007
Cdd:pfam15921  472 STKEM------LRKVVEELTAKKMtleSSERTVSDLTASLQEKERAIEATNAEitklrSRVDLKLQELQHLKNEGDHLrN 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1008 LQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKE---QRLLVLQEADSIRQQELSA 1084
Cdd:pfam15921  546 VQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRlelQEFKILKDKKDAKIRELEA 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1085 LRQDMQEAQgeQKELSAQMELLR--QEVKEKEADFLAQEAQLLEEL----EASHITEQQLRASLWAQEAKAAQLQLRLRS 1158
Cdd:pfam15921  626 RVSDLELEK--VKLVNAGSERLRavKDIKQERDQLLNEVKTSRNELnslsEDYEVLKRNFRNKSEEMETTTNKLKMQLKS 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1159 TESQLEalaaeqqpgnqaQAQAQLASLYSALQQALGSVCESRPELSGggdsapsvwglepdqngarslfKRGPLltalsa 1238
Cdd:pfam15921  704 AQSELE------------QTRNTLKSMEGSDGHAMKVAMGMQKQITA----------------------KRGQI------ 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1239 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMEL 1318
Cdd:pfam15921  744 DALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAEC 823

                          650
                   ....*....|....*..
gi 2217334288 1319 HETMASLQSRLRRAELQ 1335
Cdd:pfam15921  824 QDIIQRQEQESVRLKLQ 840
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 438-1196 5.73e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.63  E-value: 5.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  438 QKLTGERDTLAGQTVDLQGEVDSLskeRELLQKAREELRQQLEVLEQEAWR---LRRVNVELQLQGDSAQGQKEEQQEEL 514
Cdd:pfam01576  211 RKLEGESTDLQEQIAELQAQIAEL---RAQLAKKEEELQAALARLEEETAQknnALKKIRELEAQISELQEDLESERAAR 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  515 HLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLE-GELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVAD 593
Cdd:pfam01576  288 NKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEvTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQ 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  594 LRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQ---- 669
Cdd:pfam01576  368 AKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELEsvss 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  670 ---KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQ 746
Cdd:pfam01576  448 llnEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLS 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  747 AVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEvqiqtvtQAKEVIQGEVRCLKLELDTERsQAEQER 826
Cdd:pfam01576  528 DMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLE-------KTKNRLQQELDDLLVDLDHQR-QLVSNL 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  827 DAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSwhqqeLAKALESLEREKMELEMRLKEQQTEMEAIQAQRE 906
Cdd:pfam01576  600 EKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALS-----LARALEEALEAKEELERTNKQLRAEMEDLVSSKD 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  907 E------ERTQAESALCQmQLETEKERVSLLETLLQTQKelaDASQQLERLRQDMKVQKLKEQETTgilQTQLQEAQREL 980
Cdd:pfam01576  675 DvgknvhELERSKRALEQ-QVEEMKTQLEELEDELQATE---DAKLRLEVNMQALKAQFERDLQAR---DEQGEEKRRQL 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  981 KEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLS 1060
Cdd:pfam01576  748 VKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQ 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1061 LMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELS---AQMELLRQEVKEKEADFLAQEAQLLEELEashitEQQ 1137
Cdd:pfam01576  828 SKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELAdeiASGASGKSALQDEKRRLEARIAQLEEELE-----EEQ 902

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1138 LRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSV 1196
Cdd:pfam01576  903 SNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTV 961
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1314-1527 7.67e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 7.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1314 ELMELHETMASLQSRLRRaeLQRMEAQGERelLQAAKENLTAQVEHLQAAVVEARAQASAAgiLEEDLRTARSAL-KLKN 1392
Cdd:COG4913    236 DLERAHEALEDAREQIEL--LEPIRELAER--YAAARERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELaRLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1393 EEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEV 1472
Cdd:COG4913    310 ELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1473 DLQQEQIQELEKcrsvlehlpmAVQEREQKLTVQREQIRELEKDRETQRNVLEHQ 1527
Cdd:COG4913    390 AALLEALEEELE----------ALEEALAEAEAALRDLRRELRELEAEIASLERR 434
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 462-740 8.98e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 8.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  462 SKERELLQKAREELRQQLEVLEQEawrlrrvnvelqlqgdsaqgqkeeqqeelhlavrererlqemLMGLEAKQSESLSE 541
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKE------------------------------------------LAALKKEEKALLKQ 56

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  542 LITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALAldkvglnqqLLQ 621
Cdd:COG4942     57 LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLAL---------LLS 127

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  622 LEEENQSVcSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRH 701
Cdd:COG4942    128 PEDFLDAV-RRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEK 206

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 2217334288  702 QQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAA 740
Cdd:COG4942    207 ELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1282-2123 9.03e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 9.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1282 QVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQ 1361
Cdd:pfam02463  189 IIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1362 AAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLR 1441
Cdd:pfam02463  269 QVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1442 GQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEhlpmavQEREQKLTVQREQIRELEKDRETQR 1521
Cdd:pfam02463  349 IKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL------ELKSEEEKEAQLLLELARQLEDLLK 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1522 NVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRetQRVALTHLTLDLEERS 1601
Cdd:pfam02463  423 EEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE--QLELLLSRQKLEERSQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1602 QELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLE---RRDQELMLQKERIQVLEDQRTRQT 1678
Cdd:pfam02463  501 KESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVsatADEVEERQKLVRALTELPLGARKL 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1679 KILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKE-----------VECQQEHIHE 1747
Cdd:pfam02463  581 RLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKEsakakesglrkGVSLEEGLAE 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1748 LQELKDQLEQQLQGLHRKVgETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQ 1827
Cdd:pfam02463  661 KSEVKASLSELTKELLEIQ-ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELK 739

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1828 QAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQ 1907
Cdd:pfam02463  740 LLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEE 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1908 QQCAEQAQEHEVETRALQdswLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQ 1987
Cdd:pfam02463  820 EQLLIEQEEKIKEEELEE---LALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEK 896

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1988 AELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQ 2067
Cdd:pfam02463  897 EEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVN 976

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217334288 2068 RVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLE 2123
Cdd:pfam02463  977 LMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKG 1032
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
565-1114 1.16e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 1.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  565 EVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALAldkvGLNQQLLQLEEENQSVCSRMEAAEQARNALQ 644
Cdd:PRK03918   197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE----ELEKELESLEGSKRKLEEKIRELEERIEELK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  645 VDLAEAEKRREALWE------KNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSEsrhqqeaattqLEQLHQEAK 718
Cdd:PRK03918   273 KEIEELEEKVKELKElkekaeEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKE-----------LEEKEERLE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  719 RQEEvlaravqEKEALVREKAALEVRLQAVERDRQdLAEQLQGLSSAKELLesslfeaqqqnsvievTKGQLEVQIQTVT 798
Cdd:PRK03918   342 ELKK-------KLKELEKRLEELEERHELYEEAKA-KKEELERLKKRLTGL----------------TPEKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  799 QAKEVIQGEVRCLKLELdTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALE 878
Cdd:PRK03918   398 KAKEEIEEEISKITARI-GELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  879 SLEREKMELEMRLKEQQTemeaIQAQRE--EERTQAESALCQMQLETEKERVSLLETLlqtQKELADASQQLERLRQDMK 956
Cdd:PRK03918   477 KLRKELRELEKVLKKESE----LIKLKElaEQLKELEEKLKKYNLEELEKKAEEYEKL---KEKLIKLKGEIKSLKKELE 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  957 VQKLKEQETTgILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQ---VEDLKSQLVAQDDSQRLVEQEV 1033
Cdd:PRK03918   550 KLEELKKKLA-ELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEyleLKDAEKELEREEKELKKLEEEL 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1034 QEKLRETQEYNRIQKELEREKASLTLSLMEKEQRllVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEK 1113
Cdd:PRK03918   629 DKAFEELAETEKRLEELRKELEELEKKYSEEEYE--ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706


                   .
gi 2217334288 1114 E 1114
Cdd:PRK03918   707 E 707
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 229-485 1.26e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 1.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  229 SREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQELiqlksqgdlekAELQDRVTELSALLTQSQKQNEDYEKMIKA 308
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL-----------RRIENRLDELSQELSDASRKIGEIEKEIEQ 727

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  309 LRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEegdnIAQGSGHENSLE--LDSSIFSQFD--YQDA 384
Cdd:TIGR02169  728 LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEED----LHKLEEALNDLEarLSHSRIPEIQaeLSKL 803

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  385 DKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKE 464
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883

                          250       260
                   ....*....|....*....|.
gi 2217334288  465 RELLQKAREELRQQLEVLEQE 485
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERK 904
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 648-1040 1.55e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 46.93  E-value: 1.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  648 AEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLrdiqeekEEIQKKLSESRHQQEAA-TTQLEQLHQEAKRQEEVLaR 726
Cdd:NF033838    37 AEEVRGGNNPTVTSSGNESQKEHAKEVESHLEKIL-------SEIQKSLDKRKHTQNVAlNKKLSDIKTEYLYELNVL-K 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  727 AVQEKEALVREKAALEVrlqAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQnsvievtKGQLEVQIQTVTQAK---EV 803
Cdd:NF033838   109 EKSEAELTSKTKKELDA---AFEQFKKDTLEPGKKVAEATKKVEEAEKKAKDQ-------KEEDRRNYPTNTYKTlelEI 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  804 IQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTAleqqKAAHEKEVNQLREKWEKE-RSWHQQELAKALESL-- 880
Cdd:NF033838   179 AESDVEVKKAELELVKEEAKEPRDEEKIKQAKAKVESKKA----EATRLEKIKTDREKAEEEaKRRADAKLKEAVEKNva 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  881 EREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQmqlETekervsLLETLLQTQKELADASQQLERLRQDMKVQKL 960
Cdd:NF033838   255 TSEQDKPKRRAKRGVLGEPATPDKKENDAKSSDSSVGE---ET------LPSPSLKPEKKVAEAEKKVEEAKKKAKDQKE 325

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  961 KEQE-----TTGILQTQLQEAQRELKEA--------ARQHRDD--LAALQEESSSLLQDKMDLQKQVEDLKSqlvAQDDS 1025
Cdd:NF033838   326 EDRRnyptnTYKTLELEIAESDVKVKEAelelvkeeAKEPRNEekIKQAKAKVESKKAEATRLEKIKTDRKK---AEEEA 402

                          410
                   ....*....|....*..
gi 2217334288 1026 QRLVEQE--VQEKLRET 1040
Cdd:NF033838   403 KRKAAEEdkVKEKPAEQ 419
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
572-784 1.64e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.93  E-value: 1.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  572 RAEQSIAELSSSENTLKTEVADLRAaavKLSALNEALAldKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAE 651
Cdd:COG3206    165 NLELRREEARKALEFLEEQLPELRK---ELEEAEAALE--EFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  652 KRREALWEKN----------------THLEAQLQKAEEAGAELQADLRD----IQEEKEEIQKKLSESRHQQEAATTQLE 711
Cdd:COG3206    240 ARLAALRAQLgsgpdalpellqspviQQLRAQLAELEAELAELSARYTPnhpdVIALRAQIAALRAQLQQEAQRILASLE 319

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217334288  712 QLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIE 784
Cdd:COG3206    320 AELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVRVID 392
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 817-1140 1.71e-04

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 46.45  E-value: 1.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  817 TERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQT 896
Cdd:pfam13868   22 KERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQERE 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  897 EMEAIQAQREEERtqaesalcqmqletEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEA 976
Cdd:pfam13868  102 QMDEIVERIQEED--------------QAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAER 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  977 QRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKAS 1056
Cdd:pfam13868  168 EEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAREEQIEL 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1057 ltLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQ 1136
Cdd:pfam13868  248 --KERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERLREEEA 325


                   ....
gi 2217334288 1137 QLRA 1140
Cdd:pfam13868  326 ERRE 329
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
857-1033 1.82e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 1.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  857 QLREKWEKERSWhqQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERvslLETLLQ 936
Cdd:COG4717     79 ELKEAEEKEEEY--AELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPER---LEELEE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  937 TQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLK 1016
Cdd:COG4717    154 RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE 233

                          170
                   ....*....|....*..
gi 2217334288 1017 SQLVAQDDSQRLVEQEV 1033
Cdd:COG4717    234 NELEAAALEERLKEARL 250
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 664-805 1.87e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 46.74  E-value: 1.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  664 LEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSEsrhQQEAATTQLEQLHQEAKrqeEVLARAVQEKEALVREKAALEv 743
Cdd:PRK00409   525 LEELERELEQKAEEAEALLKEAEKLKEELEEKKEK---LQEEEDKLLEEAEKEAQ---QAIKEAKKEADEIIKELRQLQ- 597

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217334288  744 RLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVtkGQlEVQIQTVTQAKEVIQ 805
Cdd:PRK00409   598 KGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELKV--GD-EVKYLSLGQKGEVLS 656
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 559-926 1.88e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  559 LRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAavkLSALNEALALDKVGLNQQ--LLQLEEENQSVCSRMEAA 636
Cdd:COG3096    290 LRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQD---YQAASDHLNLVQTALRQQekIERYQEDLEELTERLEEQ 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  637 EQARNALQVDLAEAEKRREALWEKNTHLEAQL-----------------QKAEEAGAELQADLRDIQEEKEEIQKKLSES 699
Cdd:COG3096    367 EEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLadyqqaldvqqtraiqyQQAVQALEKARALCGLPDLTPENAEDYLAAF 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  700 RHQQEAATTQLEQLHQ------EAKRQEEVLARAVQEKEALVREKAALEVRLQAVE--RDRQDLAEQLQGLssakellES 771
Cdd:COG3096    447 RAKEQQATEEVLELEQklsvadAARRQFEKAYELVCKIAGEVERSQAWQTARELLRryRSQQALAQRLQQL-------RA 519

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  772 SLFEAQQQnsvievtkgqLEVQIQTVTQAKEVIQGEVRCL--KLELDTERSQAEQERDAAARQLAQAeQEGKTALEQQKA 849
Cdd:COG3096    520 QLAELEQR----------LRQQQNAERLLEEFCQRIGQQLdaAEELEELLAELEAQLEELEEQAAEA-VEQRSELRQQLE 588

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288  850 AHEKEVNQLRekwEKERSWHqqelaKALESLEREKMELEMRLKEQQTEMEAIQ--AQREEERTQAESALCQMQLETEKE 926
Cdd:COG3096    589 QLRARIKELA---ARAPAWL-----AAQDALERLREQSGEALADSQEVTAAMQqlLEREREATVERDELAARKQALESQ 659
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1778-1955 1.89e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 1.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1778 QEIVVLQQQLQEAREQ-GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKE 1856
Cdd:COG4913    255 EPIRELAERYAAARERlAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1857 RHGE-LQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVL 1935
Cdd:COG4913    335 NGGDrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAAL 414

                          170       180
                   ....*....|....*....|
gi 2217334288 1936 KERDQELEALRAESQSSRHQ 1955
Cdd:COG4913    415 RDLRRELRELEAEIASLERR 434
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
741-996 2.00e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.55  E-value: 2.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  741 LEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIevtkgQLEVQIQTVTQAKEviqgevrclklELDTERS 820
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLV-----DLSEEAKLLLQQLS-----------ELESQLA 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  821 QAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQlrekwekerswhqqELAKALESLEREKMELEMRLKEQQTEMEA 900
Cdd:COG3206    230 EARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQ--------------QLRAQLAELEAELAELSARYTPNHPDVIA 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  901 IQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQdmkvqklkeqettgiLQTQLQEAQREL 980
Cdd:COG3206    296 LRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPE---------------LEAELRRLEREV 360

                          250
                   ....*....|....*.
gi 2217334288  981 KEAARQHRDDLAALQE 996
Cdd:COG3206    361 EVARELYESLLQRLEE 376
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 621-1124 2.31e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.55  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  621 QLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQ-------LQKAEEAGAELQADLRDIQEE----K 689
Cdd:TIGR04523   37 QLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQikdlndkLKKNKDKINKLNSDLSKINSEikndK 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  690 EEIQKK---LSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSS-- 764
Cdd:TIGR04523  117 EQKNKLeveLNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNkl 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  765 -AKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLEL---DTERSQAEQERDAAARQLAQAEQEG 840
Cdd:TIGR04523  197 lKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEIsntQTQLNQLKDEQNKIKKQLSEKQKEL 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  841 KTAlEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESlerekmelemRLKEQQTEMEAIQAQREEErTQAESALCQMQ 920
Cdd:TIGR04523  277 EQN-NKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKS----------ELKNQEKKLEEIQNQISQN-NKIISQLNEQI 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  921 LETEKERVSLLETLLQTQKELADASQQLERLR--QDMKVQKLKEQET-TGILQTQLQEAQRELKEaarqhrddlaaLQEE 997
Cdd:TIGR04523  345 SQLKKELTNSESENSEKQRELEEKQNEIEKLKkeNQSYKQEIKNLESqINDLESKIQNQEKLNQQ-----------KDEQ 413

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  998 SSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSI 1077
Cdd:TIGR04523  414 IKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKS 493

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 2217334288 1078 RQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQL 1124
Cdd:TIGR04523  494 KEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKI 540
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1256-1948 2.37e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.58  E-value: 2.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1256 QQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQ 1335
Cdd:TIGR00606  348 EQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQ 427

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1336 ----RMEAQGERELLQAAKENLTAQVEHLQAAVVEAR-AQASAAGILE--EDLRTARSALKL--KNEEVESERERAQALQ 1406
Cdd:TIGR00606  428 adeiRDEKKGLGRTIELKKEILEKKQEELKFVIKELQqLEGSSDRILEldQELRKAERELSKaeKNSLTETLKKEVKSLQ 507

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1407 -EQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSL--DLKKRNQEVDLQQEQIQELE 1483
Cdd:TIGR00606  508 nEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgYFPNKKQLEDWLHSKSKEIN 587

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1484 KCRSVLEHLPMAVQEREQkltvQREQIRELEKDRETQRNVLEHQLLEL---EKKDQMIESQRGQVQDLKKQLV-----TL 1555
Cdd:TIGR00606  588 QTRDRLAKLNKELASLEQ----NKNHINNELESKEEQLSSYEDKLFDVcgsQDEESDLERLKEEIEKSSKQRAmlagaTA 663

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1556 ECLALELEENHHKMECQQKLIKELEGQRETQRVA------LTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERD 1629
Cdd:TIGR00606  664 VYSQFITQLTDENQSCCPVCQRVFQTEAELQEFIsdlqskLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKE 743

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1630 QEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKIleedlEQIKLSLRERGRELTTQRQLMQer 1709
Cdd:TIGR00606  744 KEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIM-----ERFQMELKDVERKIAQQAAKLQ-- 816

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1710 aeegkgpSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGEtsllLSQREQEIVVLQQQLQE 1789
Cdd:TIGR00606  817 -------GSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE----LKSEKLQIGTNLQRRQQ 885

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1790 AREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQAR 1869
Cdd:TIGR00606  886 FEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQ 965

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1870 RLEEELAVEgrRVQALEEVLGDLRAESREQEKallalqQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAE 1948
Cdd:TIGR00606  966 DGKDDYLKQ--KETELNTVNAQLEECEKHQEK------INEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEE 1036
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
831-1450 2.48e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  831 RQLAQAEQEGKTALEQQKAahekeVNQLREKWEKerswhQQELAKALESLEREKMELemRLKEQQTEMEAIQAQREEERT 910
Cdd:COG4913    235 DDLERAHEALEDAREQIEL-----LEPIRELAER-----YAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRA 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  911 QAESALCQMQlETEKERVSLLETLLQTQKELADAS-QQLERLRQDMKVQKLKEQETTGILQtQLQEAQRELKEAARQHRD 989
Cdd:COG4913    303 ELARLEAELE-RLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRA-RLEALLAALGLPLPASAE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  990 DLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQddsqrlvEQEVQEKLREtqeynriqkeLEREKASLtlslmeKEQRLL 1069
Cdd:COG4913    381 EFAALRAEAAALLEALEEELEALEEALAEAEAA-------LRDLRRELRE----------LEAEIASL------ERRKSN 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1070 VLQEADSIRQQELSALRQDmqeaqgeQKELSAQMELLrqEVKEKEADFL------------------AQEAQLLEELEAS 1131
Cdd:COG4913    438 IPARLLALRDALAEALGLD-------EAELPFVGELI--EVRPEEERWRgaiervlggfaltllvppEHYAAALRWVNRL 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1132 HiteqqLRASLWAQEAKAAQLQLRLRSTESQleALAAEqqpgnqaqAQAQLASLYSALQQALGSV-----CESRPELSGG 1206
Cdd:COG4913    509 H-----LRGRLVYERVRTGLPDPERPRLDPD--SLAGK--------LDFKPHPFRAWLEAELGRRfdyvcVDSPEELRRH 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1207 GdsapsvwglepdqngarslfkrgpllTALSAEAVASALHKLHQ-DLWKTQQTRDVL----RDQVQKLEERLTDTEAEKS 1281
Cdd:COG4913    574 P--------------------------RAITRAGQVKGNGTRHEkDDRRRIRSRYVLgfdnRAKLAALEAELAELEEELA 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1282 QVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMelhetMASLQSRLRRAELQRMEAQGERELLQAAKEnltaQVEHLQ 1361
Cdd:COG4913    628 EAEERLEALEAELDALQERREALQRLAEYSWDEID-----VASAEREIAELEAELERLDASSDDLAALEE----QLEELE 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1362 AAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAER-EEEVETL 1440
Cdd:COG4913    699 AELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENlEERIDAL 778

                          650
                   ....*....|
gi 2217334288 1441 RGQIQELEKQ 1450
Cdd:COG4913    779 RARLNRAEEE 788
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1289-1781 3.10e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.37  E-value: 3.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1289 DLQRQLSQNQEEKSKWEGKQNSLESELMELhetmASLQSRLRRAELQRMEAQGERELLQAAKENLTAQvehLQAAVVEAR 1368
Cdd:pfam12128  231 QAIAGIMKIRPEFTKLQQEFNTLESAELRL----SHLHFGYKSDETLIASRQEERQETSAELNQLLRT---LDDQWKEKR 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1369 AQASAagileeDLRTARSALKLKNEEVESERERAQALQEQGelkVAQGKALQENLALLTQTLAEREEEVETLRGQIQELE 1448
Cdd:pfam12128  304 DELNG------ELSAADAAVAKDRSELEALEDQHGAFLDAD---IETAAADQEQLPSWQSELENLEERLKALTGKHQDVT 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1449 KQREMQKAALEL-LSLDLKKRNQEVDLQQEQI-QELEKCRSVLEHLPMAVQER-EQKLTVQREQIRELE------KDRET 1519
Cdd:pfam12128  375 AKYNRRRSKIKEqNNRDIAGIKDKLAKIREARdRQLAVAEDDLQALESELREQlEAGKLEFNEEEYRLKsrlgelKLRLN 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1520 QRNVLEHQLLELEKKDQMIESQRGQVQDLKKqlvtleclaleleenhhKMECQQKLIKELEGQRETQRVALTHLTLDLEE 1599
Cdd:pfam12128  455 QATATPELLLQLENFDERIERAREEQEAANA-----------------EVERLQSELRQARKRRDQASEALRQASRRLEE 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1600 RSQELQAQSSQ--------IHDL--------ESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRD------ 1657
Cdd:pfam12128  518 RQSALDELELQlfpqagtlLHFLrkeapdweQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDvpewaa 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1658 QELMLQKERIQVLEDQRTRQTKI--LEEDLEQIKLSLRERGRELTTQRQ-LMQERAEEGKGPSKAQRGSLEHMKLILRDK 1734
Cdd:pfam12128  598 SEEELRERLDKAEEALQSAREKQaaAEEQLVQANGELEKASREETFARTaLKNARLDLRRLFDEKQSEKDKKNKALAERK 677

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 2217334288 1735 EKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIV 1781
Cdd:pfam12128  678 DSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVE 724
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
380-907 3.30e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.21  E-value: 3.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  380 DYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAG---------- 449
Cdd:PRK03918   159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKevkeleelke 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  450 -------QTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVN------VELQLQGDSAQGQKEEQQEELHL 516
Cdd:PRK03918   239 eieelekELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKekaeeyIKLSEFYEEYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  517 AVRERERLQEMLMGLEAKQSE------SLSELITLREALESSHLEGELLRQEQTE---------------VTAALARAEQ 575
Cdd:PRK03918   319 LEEEINGIEERIKELEEKEERleelkkKLKELEKRLEELEERHELYEEAKAKKEElerlkkrltgltpekLEKELEELEK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  576 SIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARnaLQVDLAEAEKRRE 655
Cdd:PRK03918   399 AKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKR--IEKELKEIEEKER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  656 ALWEKNTHLEAQLQKAEEAGAelqadLRDIQEEKEEIQKKLSESRHQQ-EAATTQLEQLHQEA---KRQEEVLARAVQEK 731
Cdd:PRK03918   477 KLRKELRELEKVLKKESELIK-----LKELAEQLKELEEKLKKYNLEElEKKAEEYEKLKEKLiklKGEIKSLKKELEKL 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  732 EALVREKAALEVRLQAVERDRQDLAEQLQ--GLSSAKELlesslfeaqqqnsviEVTKGQLEVQIQTVTQAKEVIQgEVR 809
Cdd:PRK03918   552 EELKKKLAELEKKLDELEEELAELLKELEelGFESVEEL---------------EERLKELEPFYNEYLELKDAEK-ELE 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  810 CLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKaLESLEREKMELEM 889
Cdd:PRK03918   616 REEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAE-LEELEKRREEIKK 694

                          570
                   ....*....|....*...
gi 2217334288  890 RLKEQQTEMEAIQAQREE 907
Cdd:PRK03918   695 TLEKLKEELEEREKAKKE 712
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1250-1795 3.42e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 3.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1250 QDLWKTQQTRdvLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQeekskwegkqnsleselmelHETMASLQSRL 1329
Cdd:COG4913    290 LELLEAELEE--LRAELARLEAELERLEARLDALREELDELEAQIRGNG--------------------GDRLEQLEREI 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1330 RRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASA-AGILEEDLRTARSAL-KLKNEEVESERERAQALQE 1407
Cdd:COG4913    348 ERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAAlLEALEEELEALEEALaEAEAALRDLRRELRELEAE 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1408 QGELKVAQG---KALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKA--------ALELL--------------S 1462
Cdd:COG4913    428 IASLERRKSnipARLLALRDALAEALGLDEAELPFVGELIEVRPEEERWRGAiervlggfALTLLvppehyaaalrwvnR 507

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1463 LDLKKRNQ----EVDLQQEQIQELEKcRSVLEHL---PMAVQEREQKLTVQR------EQIRELEK-DRETQRNVLEHQL 1528
Cdd:COG4913    508 LHLRGRLVyervRTGLPDPERPRLDP-DSLAGKLdfkPHPFRAWLEAELGRRfdyvcvDSPEELRRhPRAITRAGQVKGN 586

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1529 LELEKKDQMIESQRGQV--QDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLT------LDLEER 1600
Cdd:COG4913    587 GTRHEKDDRRRIRSRYVlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAeyswdeIDVASA 666

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1601 SQELQAQSSQIHDLESHSTVLA---RELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDqrtRQ 1677
Cdd:COG4913    667 EREIAELEAELERLDASSDDLAaleEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAED---LA 743

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1678 TKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRD---KEKEVECQQEHIHELQELKDQ 1754
Cdd:COG4913    744 RLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREwpaETADLDADLESLPEYLALLDR 823

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 2217334288 1755 LEQqlQGLHRKVGE-TSLLLSQREQEIVVLQQQLQEAREQGE 1795
Cdd:COG4913    824 LEE--DGLPEYEERfKELLNENSIEFVADLLSKLRRAIREIK 863
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2049-2226 3.44e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 3.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2049 EELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQERE--EEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALP 2126
Cdd:COG4913    262 ERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEelRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2127 hshktspmeeqslkldslepRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDS 2206
Cdd:COG4913    342 --------------------QLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE 401

                          170       180
                   ....*....|....*....|
gi 2217334288 2207 EQQRLQDELELTRRALEKER 2226
Cdd:COG4913    402 ALEEALAEAEAALRDLRREL 421
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1330-1712 3.50e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.10  E-value: 3.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1330 RRAELQRMEAQGERELlQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEevesererAQALQEqg 1409
Cdd:COG3096    279 ERRELSERALELRREL-FGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQT--------ALRQQE-- 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1410 elKVAQgkaLQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQ-------EQIQEL 1482
Cdd:COG3096    348 --KIER---YQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQtraiqyqQAVQAL 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1483 EKCRSVLEHLPMA---VQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIES-----QRGQVQDLKKQLVT 1554
Cdd:COG3096    423 EKARALCGLPDLTpenAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKiagevERSQAWQTARELLR 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1555 LECLALELEENHHKMECQQK-LIKELEGQRETQRValthltldLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVK 1633
Cdd:COG3096    503 RYRSQQALAQRLQQLRAQLAeLEQRLRQQQNAERL--------LEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAA 574

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1634 SQREQIEELQRQKEHLTQD---LERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLrERGRELTTQRQLMQERA 1710
Cdd:COG3096    575 EAVEQRSELRQQLEQLRARikeLAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLL-EREREATVERDELAARK 653


                   ..
gi 2217334288 1711 EE 1712
Cdd:COG3096    654 QA 655
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 720-950 3.95e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  720 QEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQ 799
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  800 AKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGkTALEQQKAAHEKEVNQLREKwekerswhQQELAKALES 879
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRL-QYLKYLAPARREQAEELRAD--------LAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217334288  880 LEREKMELEMRLKEQQTEMEAIQAQREEERTQAESAlcQMQLETEKERvslLETLLQTQKELADASQQLER 950
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARL--EKELAELAAE---LAELQQEAEELEALIARLEA 234
PRK11281 PRK11281
mechanosensitive channel MscK;
892-1160 4.50e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 45.67  E-value: 4.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  892 KEQQTEMEAIQAQREEErtqAESALCQMQLET-----------EKERVSLLETLLQTQKELADASQQLERLRQDMKVQKL 960
Cdd:PRK11281    39 ADVQAQLDALNKQKLLE---AEDKLVQQDLEQtlalldkidrqKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETR 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  961 KEQETTgilqtqlqeaqrelkeaarqhrdDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRET 1040
Cdd:PRK11281   116 ETLSTL-----------------------SLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRL 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1041 QEYNRIQKELEREKASLTLS---LMEKEQRLLVLQeaDSIRQQELSA--LRQDMQEAQ-----GEQKELSAQMELLRQEV 1110
Cdd:PRK11281   173 QQIRNLLKGGKVGGKALRPSqrvLLQAEQALLNAQ--NDLQRKSLEGntQLQDLLQKQrdyltARIQRLEHQLQLLQEAI 250

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2217334288 1111 KEKEadfLAQEAQLLEELEASHITEQQLRASLWAQEAkAAQLQLR---LRSTE 1160
Cdd:PRK11281   251 NSKR---LTLSEKTVQEAQSQDEAARIQANPLVAQEL-EINLQLSqrlLKATE 299
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 685-963 4.59e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.50  E-value: 4.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  685 IQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEvlaravQEKEALVREKAALEVRLQAVERDRQDLAEQ--LQGL 762
Cdd:pfam17380  301 LRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAE------QERMAMERERELERIRQEERKRELERIRQEeiAMEI 374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  763 SSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQER---DAAARQLAQAEQE 839
Cdd:pfam17380  375 SRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRrleEERAREMERVRLE 454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  840 GKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALES--LEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALC 917
Cdd:pfam17380  455 EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRkiLEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEER 534

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 2217334288  918 QMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQ 963
Cdd:pfam17380  535 RREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQ 580
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1622-1850 4.87e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1622 ARELQERDQEVKSQREQIEELQRQKEHLTQdLERRDQELMLQKERIQVLEDQRTRQTkiLEEDLEQIKLsLRERGRELTT 1701
Cdd:COG4913    227 ADALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAALR--LWFAQRRLEL-LEAELEELRA 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1702 QRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKE-KEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEI 1780
Cdd:COG4913    303 ELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEF 382

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1781 VVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQA 1850
Cdd:COG4913    383 AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEA 452
PTZ00121 PTZ00121
MAEBL; Provisional
 1986-2355 5.35e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 5.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1986 EQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALaqRDEELRHQQEREQLlekSL 2065
Cdd:PTZ00121  1082 DAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDAR--KAEEARKAEDAKRV---EI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2066 AQRVQE-NMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEE----QSLK 2140
Cdd:PTZ00121  1157 ARKAEDaRKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAvkkaEEAK 1236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2141 LDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRR 2220
Cdd:PTZ00121  1237 KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2221 ALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTL 2300
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217334288 2301 EQVERERRKLKREAMRAAQA-GSLEISKATASSPTQQDGRGQKNSDAKCVAELQKE 2355
Cdd:PTZ00121  1397 KKKAEEDKKKADELKKAAAAkKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKK 1452
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 648-874 5.37e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.82  E-value: 5.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  648 AEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVL--- 724
Cdd:COG3883     12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELger 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  725 ARAVQEKEALVREKAALEV---------RLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQ 795
Cdd:COG3883     92 ARALYRSGGSVSYLDVLLGsesfsdfldRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288  796 TVTQAKEVIQGEVRclklELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELA 874
Cdd:COG3883    172 ELEAQQAEQEALLA----QLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASA 246
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 548-988 5.76e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 45.43  E-value: 5.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  548 ALESSHLEGELLRQEQTEVTAALARAEQSIAE-LSSSENTLKTEVADLRAAAVKLSALNEALALDKvGLNQQLLQLEEEN 626
Cdd:PRK10929    17 AYAATAPDEKQITQELEQAKAAKTPAQAEIVEaLQSALNWLEERKGSLERAKQYQQVIDNFPKLSA-ELRQQLNNERDEP 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  627 QSVCSRMEAAEQARNALQVDLAEAEKRRealweknthleaQLQKAEEAGAELQADLRDIQEEKEEIQKKLS--ESRHQ-Q 703
Cdd:PRK10929    96 RSVPPNMSTDALEQEILQVSSQLLEKSR------------QAQQEQDRAREISDSLSQLPQQQTEARRQLNeiERRLQtL 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  704 EAATTQLEQLhQEAKRQEEVLARAVQEKEAlvrEKAALEVR-LQAVERDRQDLAE-QLQGLSSAKELLESSLFEAQQQNs 781
Cdd:PRK10929   164 GTPNTPLAQA-QLTALQAESAALKALVDEL---ELAQLSANnRQELARLRSELAKkRSQQLDAYLQALRNQLNSQRQRE- 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  782 vievTKGQLEVQIQTVTQAKEVIQGEVRCLKL--ELDTERSQAEQERDAAARQLAQAEQEgktaLEQQKAAhekeVNQLR 859
Cdd:PRK10929   239 ----AERALESTELLAEQSGDLPKSIVAQFKInrELSQALNQQAQRMDLIASQQRQAASQ----TLQVRQA----LNTLR 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  860 EK--WEKERSwhqqelakAL-ESLEREKMELEMRLKEQQ--TEMEAIQAQR---EE--ERTQAESALCQ---MQLETEKE 926
Cdd:PRK10929   307 EQsqWLGVSN--------ALgEALRAQVARLPEMPKPQQldTEMAQLRVQRlryEDllNKQPQLRQIRQadgQPLTAEQN 378

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217334288  927 RVslLETLLQTQKELADA------SQQLErlrqdmkVQKLKeqettgILQTQLQEAQRELKEAArqHR 988
Cdd:PRK10929   379 RI--LDAQLRTQRELLNSllsggdTLILE-------LTKLK------VANSQLEDALKEVNEAT--HR 429
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 453-677 6.04e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 6.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  453 DLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLmgle 532
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL---- 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  533 AKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAElsssenTLKTEVADLRAAAVKLSALNEALALDK 612
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAP------ARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288  613 VGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAE 677
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
622-913 6.16e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.51  E-value: 6.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  622 LEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRH 701
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  702 QQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNS 781
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  782 VIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREK 861
Cdd:COG4372    189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2217334288  862 WEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAE 913
Cdd:COG4372    269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAA 320
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1041-1143 6.47e-04

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 45.33  E-value: 6.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1041 QEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADsirqQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQ 1120
Cdd:PRK11448   142 NLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQ----QELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERKQK 217

                           90       100       110
                   ....*....|....*....|....*....|..
gi 2217334288 1121 EAQL---------LEELEASHITEQQLRASLW 1143
Cdd:PRK11448   218 RKEItdqaakrleLSEEETRILIDQQLRKAGW 249
PRK11281 PRK11281
mechanosensitive channel MscK;
871-1143 6.64e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 45.29  E-value: 6.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  871 QELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKErvSLLETLLQTQKELADASQQLER 950
Cdd:PRK11281    76 DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLA--QTLDQLQNAQNDLAEYNSQLVS 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  951 lrqdmkvqklkeqettgiLQTQLQEAQRELKEAARQhrddlaaLQEESSSLLQDKMDLQKQVEDLKSQLVAQddsQRLVE 1030
Cdd:PRK11281   154 ------------------LQTQPERAQAALYANSQR-------LQQIRNLLKGGKVGGKALRPSQRVLLQAE---QALLN 205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1031 QEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEAdsIRQQELSALRQDMQEAQGEQKELSAQM-ELLRQE 1109
Cdd:PRK11281   206 AQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEA--INSKRLTLSEKTVQEAQSQDEAARIQAnPLVAQE 283

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 2217334288 1110 --VKEKEADFLAQEAQLLEELeashiTEQQLRASLW 1143
Cdd:PRK11281   284 leINLQLSQRLLKATEKLNTL-----TQQNLRVKNW 314
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 687-1060 7.08e-04

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 44.67  E-value: 7.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  687 EEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAK 766
Cdd:pfam19220   20 EDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAAL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  767 ELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLEL---DTERSQAEQERDAAARQLAQAEQEGKta 843
Cdd:pfam19220  100 REAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKALREEAqaaEKALQRAEGELATARERLALLEQENR-- 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  844 leQQKAAHEKEVNQLREKWEKerswhQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERT--QAESALCQMQL 921
Cdd:pfam19220  178 --RLQALSEEQAAELAELTRR-----LAELETQLDATRARLRALEGQLAAEQAERERAEAQLEEAVEahRAERASLRMKL 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  922 ETEKERVSLLETLLQ----TQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQhRDDLAALQEE 997
Cdd:pfam19220  251 EALTARAAATEQLLAearnQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQFQEMQRA-RAELEERAEM 329

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217334288  998 SSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEynRIQKELEREKASLTLS 1060
Cdd:pfam19220  330 LTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAALEQANR--RLKEELQRERAERALA 390
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1285-1526 7.93e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.89  E-value: 7.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1285 TELQDLQRQLSqnqeEKSKWEGKQNSLESELMELH-------------ETMASLQSRLRRAELQRMEAQG--------ER 1343
Cdd:PLN02939   153 QALEDLEKILT----EKEALQGKINILEMRLSETDariklaaqekihvEILEEQLEKLRNELLIRGATEGlcvhslskEL 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1344 ELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDlrtaRSALKLKNEEVESERERAQA-LQEQGELKVAQGKALQEN 1422
Cdd:PLN02939   229 DVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKE----RSLLDASLRELESKFIVAQEdVSKLSPLQYDCWWEKVEN 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1423 LALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDlKKRNQEVDLQQEQIQELEkcrsvlEHLPMAVQEREQK 1502
Cdd:PLN02939   305 LQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEANVS-KFSSYKVELLQQKLKLLE------ERLQASDHEIHSY 377

                          250       260
                   ....*....|....*....|....*....
gi 2217334288 1503 LTVQREQIRELEKD-----RETQRNVLEH 1526
Cdd:PLN02939   378 IQLYQESIKEFQDTlsklkEESKKRSLEH 406
46 PHA02562
endonuclease subunit; Provisional
 844-1070 8.41e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 8.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  844 LEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEmRLKEQQTEMEAIQaqreEERTQAESALCQ--MQL 921
Cdd:PHA02562   193 IQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIE-ELTDELLNLVMDI----EDPSAALNKLNTaaAKI 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  922 ETEKERVSLLETLLQTQKELADASQQLERlrQDMKVQKLKEQETTgiLQTQLQEAQrelkeaarQHRDDLAALQEESSSL 1001
Cdd:PHA02562   268 KSKIEQFQKVIKMYEKGGVCPTCTQQISE--GPDRITKIKDKLKE--LQHSLEKLD--------TAIDELEEIMDEFNEQ 335

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217334288 1002 LQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQ----EKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLV 1070
Cdd:PHA02562   336 SKKLLELKNKISTNKQSLITLVDKAKKVKAAIEelqaEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGIV 408
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
555-852 8.95e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.12  E-value: 8.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  555 EGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALdkvgLNQQLLQLEEENQSVCSRME 634
Cdd:COG4372     22 TGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQ----LEEELEELNEQLQAAQAELA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  635 AAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLH 714
Cdd:COG4372     98 QAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALS 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  715 QEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQI 794
Cdd:COG4372    178 EAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVIL 257

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2217334288  795 QTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHE 852
Cdd:COG4372    258 KEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALED 315
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1808-2032 9.00e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 9.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1808 AQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEE 1887
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1888 VLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQ 1967
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1968 EALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLR 2032
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1435-1655 1.03e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1435 EEVETLRGQIQELEKQREmQKAALEllslDLKKRNQEVDLQQEQIQELEKCRSVLEHlpmavQEREQKLTVQREQIRELE 1514
Cdd:COG4913    232 EHFDDLERAHEALEDARE-QIELLE----PIRELAERYAAARERLAELEYLRAALRL-----WFAQRRLELLEAELEELR 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1515 KDR---ETQRNVLEHQLLELEKKDQMIESQR-----GQVQDLKKQLVTLeclaleleenhhkmecqQKLIKELEGQRETQ 1586
Cdd:COG4913    302 AELarlEAELERLEARLDALREELDELEAQIrgnggDRLEQLEREIERL-----------------ERELEERERRRARL 364

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1587 RVALTHLTLDLEERSQELQAQSSQIHDLeshSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLER 1655
Cdd:COG4913    365 EALLAALGLPLPASAEEFAALRAEAAAL---LEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 620-1357 1.14e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  620 LQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGaELQADLRDIQEEKEEIQKKLSES 699
Cdd:TIGR00618  208 LCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLK-QLRARIEELRAQEAVLEETQERI 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  700 RHQQEAATTQLEQLHQEAKRQEevLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQ 779
Cdd:TIGR00618  287 NRARKAAPLAAHIKAVTQIEQQ--AQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVA 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  780 NSVIEVTKGQLEVQ--IQTVTQAKEVIQGEVRCLKLELDTERSQAEQE--RDAAARQLAQ--AEQEGKTALEQQKAAHEK 853
Cdd:TIGR00618  365 TSIREISCQQHTLTqhIHTLQQQKTTLTQKLQSLCKELDILQREQATIdtRTSAFRDLQGqlAHAKKQQELQQRYAELCA 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  854 EVNQLREKWEKERSWHQQELAKALESLEREKMELEMrLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLET 933
Cdd:TIGR00618  445 AAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQ-IHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNP 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  934 LLQTQKeladasqqLERLRQDMKVQKLKEQETTGILQTQLQEAQReLKEAARQHRDDLAALQEESSSLLQDKMDLQKQVE 1013
Cdd:TIGR00618  524 GPLTRR--------MQRGEQTYAQLETSEEDVYHQLTSERKQRAS-LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1014 DLKSQLVAQD---DSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEaDSIRQQELSALRQDMQ 1090
Cdd:TIGR00618  595 RLQDLTEKLSeaeDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQ-ERVREHALSIRVLPKE 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1091 EAQGEQKELSAQMELLRQEVKEKEADFLAQEA--QLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAA 1168
Cdd:TIGR00618  674 LLASRQLALQKMQSEKEQLTYWKEMLAQCQTLlrELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQAR 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1169 EQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKL 1248
Cdd:TIGR00618  754 TVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQF 833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1249 HQDLWKTQQTRDVLRDQVQKLEERltdteaekSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELME--LHETMASLQ 1326
Cdd:TIGR00618  834 LSRLEEKSATLGEITHQLLKYEEC--------SKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIkfLHEITLYAN 905

                          730       740       750
                   ....*....|....*....|....*....|.
gi 2217334288 1327 SRLRRAELQRMEAQGERELLQAAKENLTAQV 1357
Cdd:TIGR00618  906 VRLANQSEGRFHGRYADSHVNARKYQGLALL 936
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 687-986 1.16e-03

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 43.75  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  687 EEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAK 766
Cdd:pfam13868   29 AEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  767 ELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVR---------CLKLELDTERSQAEQERDAAARQLAQAE 837
Cdd:pfam13868  109 RIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEReederileyLKEKAEREEEREAEREEIEEEKEREIAR 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  838 QEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALC 917
Cdd:pfam13868  189 LRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAREEQIELKERRLAEEAEREEEEFERMLR 268

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288  918 QMQLETEKERVSLLETLLQtQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQ 986
Cdd:pfam13868  269 KQAEDEEIEQEEAEKRRMK-RLEHRRELEKQIEEREEQRAAEREEELEEGERLREEEAERRERIEEERQ 336
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 623-1138 1.24e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.40  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  623 EEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQ-------KAEEAGAELQADLRDIQEEKEEIQKK 695
Cdd:pfam01576    4 EEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQaetelcaEAEEMRARLAARKQELEEILHELESR 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  696 LSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFE 775
Cdd:pfam01576   84 LEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISE 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  776 AQQQ-NSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTA-LEQQKAAHEK 853
Cdd:pfam01576  164 FTSNlAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAeLRAQLAKKEE 243

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  854 EVNQLREKWEKERSWHQQELAKAleslerekMELEMRLKEQQTEMEAIQAQREeertQAESALCQMQLETEKERVSLLET 933
Cdd:pfam01576  244 ELQAALARLEEETAQKNNALKKI--------RELEAQISELQEDLESERAARN----KAEKQRRDLGEELEALKTELEDT 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  934 LLQTqkeladASQQLERLRQDMKVQKLKE--QETTGILQTQLQE-------AQRELKEAARQHRDDLAALQEESSSLLQD 1004
Cdd:pfam01576  312 LDTT------AAQQELRSKREQEVTELKKalEEETRSHEAQLQEmrqkhtqALEELTEQLEQAKRNKANLEKAKQALESE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1005 KMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSA 1084
Cdd:pfam01576  386 NAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSS 465

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2217334288 1085 LRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQL 1138
Cdd:pfam01576  466 LESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQL 519
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 893-1473 1.34e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 44.02  E-value: 1.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  893 EQQTEMEAIQAQREEERTQAESALCQMQL--------ETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLK--- 961
Cdd:PRK10246   217 QVQSLTASLQVLTDEEKQLLTAQQQQQQSlnwltrldELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPARQLRphw 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  962 ---EQETTGILQT--QLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLqkqvedlkSQLVAQDDSQRLVEQEV--- 1033
Cdd:PRK10246   297 eriQEQSAALAHTrqQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSL--------NTWLAEHDRFRQWNNELagw 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1034 ----QEKLRETQEYNRIQKEL---EREKASL---TLSLMEKE---------------QRLLVLQEADSIRQQELSALRQD 1088
Cdd:PRK10246   369 raqfSQQTSDREQLRQWQQQLthaEQKLNALpaiTLTLTADEvaaalaqhaeqrplrQRLVALHGQIVPQQKRLAQLQVA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1089 MQEAQGEQKELSAQMELLRQEVKEKEADFL----------------AQEAQL----------------LEELEASHITEQ 1136
Cdd:PRK10246   449 IQNVTQEQTQRNAALNEMRQRYKEKTQQLAdvkticeqearikdleAQRAQLqagqpcplcgstshpaVEAYQALEPGVN 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1137 QLRasLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASlySALQQALGSVCES-RPELSGGGDSAPSVWG 1215
Cdd:PRK10246   529 QSR--LDALEKEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEE--QALTQQWQAVCASlNITLQPQDDIQPWLDA 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1216 LEPDQNGARSLFKRGPLLTALSAEAvasalHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKS-------------Q 1282
Cdd:PRK10246   605 QEEHERQLRLLSQRHELQGQIAAHN-----QQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEASwlatrqqeaqswqQ 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1283 VHTELQDLQRQLSQNQ-------EEKSKWEGKQNSLESELMELHETMASLQSRLrrAELQRMEAQgERELLQAAkenlTA 1355
Cdd:PRK10246   680 RQNELTALQNRIQQLTplletlpQSDDLPHSEETVALDNWRQVHEQCLSLHSQL--QTLQQQDVL-EAQRLQKA----QA 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1356 QVEHLQAAVVEARAQASAAGILEEDLRTARSALKlknEEVESERERAQALQEQGELKVAQGKALQ----------ENLAL 1425
Cdd:PRK10246   753 QFDTALQASVFDDQQAFLAALLDEETLTQLEQLK---QNLENQRQQAQTLVTQTAQALAQHQQHRpdgldltvtvEQIQQ 829

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 2217334288 1426 LTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVD 1473
Cdd:PRK10246   830 ELAQLAQQLRENTTRQGEIRQQLKQDADNRQQQQALMQQIAQATQQVE 877
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1731-1952 1.38e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1731 LRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQR 1810
Cdd:COG4942     36 IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYR 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1811 ALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEqahmtlkerhgELQDHKEQARRLEEELAVEGRRVQALEEVLG 1890
Cdd:COG4942    116 LGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE-----------ELRADLAELAALRAELEAERAELEALLAELE 184

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217334288 1891 DLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSS 1952
Cdd:COG4942    185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
969-1167 1.44e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  969 LQTQLQEAQRELKEAarqhRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQK 1048
Cdd:COG4372     43 LQEELEQLREELEQA----REELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELE 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1049 ELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEEL 1128
Cdd:COG4372    119 ELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEK 198

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 2217334288 1129 EASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALA 1167
Cdd:COG4372    199 EEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSA 237
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 98-832 1.60e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.95  E-value: 1.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288   98 ELLVRLEEEQQRCESLAEVntQLRLHMEKADVVNKaLREDVEKLtvDWSRARDELMRKESQWQMEQefFKGYLKGEHGRL 177
Cdd:pfam15921  114 DLQTKLQEMQMERDAMADI--RRRESQSQEDLRNQ-LQNTVHEL--EAAKCLKEDMLEDSNTQIEQ--LRKMMLSHEGVL 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  178 LSLWREVVTFRR---------------HFLEMKSATDRDLMELKAEHVRLSGSLLTCCLRLtvgaQSREPNGSGRMDgre 242
Cdd:pfam15921  187 QEIRSILVDFEEasgkkiyehdsmstmHFRSLGSAISKILRELDTEISYLKGRIFPVEDQL----EALKSESQNKIE--- 259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  243 paqlLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETnhtE 322
Cdd:pfam15921  260 ----LLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRS---E 332

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  323 LMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEgDNIAQGSGHensleLDSSIFSQF-DYQDADKALTLvrsvltrRRQA 401
Cdd:pfam15921  333 LREAKRMYEDKIEELEKQLVLANSELTEARTER-DQFSQESGN-----LDDQLQKLLaDLHKREKELSL-------EKEQ 399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  402 VQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGE-RDTLAGQTVDLQGEVDSLSK----------ERELLQK 470
Cdd:pfam15921  400 NKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMAAIQGKNESLEKvssltaqlesTKEMLRK 479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  471 AREELRQQLEVLEQEAWRLRRVNVELQlQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALE 550
Cdd:pfam15921  480 VVEELTAKKMTLESSERTVSDLTASLQ-EKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMA 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  551 SSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVC 630
Cdd:pfam15921  559 EKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLV 638

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  631 SrmEAAEQARNalqvdLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLsesRHQQEAATTQL 710
Cdd:pfam15921  639 N--AGSERLRA-----VKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKL---KMQLKSAQSEL 708

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  711 EQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQL 790
Cdd:pfam15921  709 EQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 2217334288  791 EVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQ 832
Cdd:pfam15921  789 AGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQ 830
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2047-2324 1.72e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 1.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2047 RDEELRHQQEREQLLE---KSLAQRVQENMIQEKQNLGQ-EREEEEIRGLHQSVRELQLTLAQKEQEILEL-RETQQRNN 2121
Cdd:TIGR02169  207 REKAERYQALLKEKREyegYELLKEKEALERQKEAIERQlASLEEELEKLTEEISELEKRLEEIEQLLEELnKKIKDLGE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2122 LEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAR------EIE-WREKAQDLALSLAQTKASVSSLQEVA 2194
Cdd:TIGR02169  287 EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEidkllaEIEeLEREIEEERKRRDKLTEEYAELKEEL 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2195 MFLQASVLERDSEQQRLQDELELTRRALEK-ERLHSPGATSTAELGSRGEQGVQLG-----EVSGVEAEPSPDGMEKQSW 2268
Cdd:TIGR02169  367 EDLRAELEEVDKEFAETRDELKDYREKLEKlKREINELKRELDRLQEELQRLSEELadlnaAIAGIEAKINELEEEKEDK 446

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217334288 2269 RQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRA-AQAGSLE 2324
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAeAQARASE 503
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 427-982 2.32e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 43.25  E-value: 2.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  427 EEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKEREL---LQKAREELRQQLEVLEQEAWRLRRVNV--------- 494
Cdd:PRK10246   215 PEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDELqqeASRRQQALQQALAAEEKAQPQLAALSLaqparqlrp 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  495 --ELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQT---EVTAA 569
Cdd:PRK10246   295 hwERIQEQSAALAHTRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSLNTWLAEHDRFRQWNNELAgwrAQFSQ 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  570 LARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVG----LNQQLLQLEEENQSVCSRMEAAEQARNALQV 645
Cdd:PRK10246   375 QTSDREQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAALAQHAeqrpLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQ 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  646 DLAEA----EKRREALWEKNTHL---------EAQLQKAEEAGAELQA---------------------DLRDIQEEKEE 691
Cdd:PRK10246   455 EQTQRnaalNEMRQRYKEKTQQLadvkticeqEARIKDLEAQRAQLQAgqpcplcgstshpaveayqalEPGVNQSRLDA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  692 IQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQglssAKELLES 771
Cdd:PRK10246   535 LEKEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVCASLNITLQPQDDIQPWLD----AQEEHER 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  772 SLFEAQQQNSVievtKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAA--------RQLAQAEQEGKTA 843
Cdd:PRK10246   611 QLRLLSQRHEL----QGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEASwlatrqqeAQSWQQRQNELTA 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  844 LEQQKAAHEKEVNQLREK-----------WEKERSWHQQ--ELAKALESLEREKMELEMRLKEQQTEME-AIQAQREEER 909
Cdd:PRK10246   687 LQNRIQQLTPLLETLPQSddlphseetvaLDNWRQVHEQclSLHSQLQTLQQQDVLEAQRLQKAQAQFDtALQASVFDDQ 766

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217334288  910 TQAESALCQ----MQLETEKERvslLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKE 982
Cdd:PRK10246   767 QAFLAALLDeetlTQLEQLKQN---LENQRQQAQTLVTQTAQALAQHQQHRPDGLDLTVTVEQIQQELAQLAQQLRE 840
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
445-713 2.33e-03

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 43.14  E-value: 2.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  445 DTLAGQTVDLQgEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQlqgdsaqgqkeeqqeELHLAVRERERL 524
Cdd:COG0497    148 DAFAGLEELLE-EYREAYRAWRALKKELEELRADEAERARELDLLRFQLEELE---------------AAALQPGEEEEL 211

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  525 QEmlmgleakQSESLSELITLREALESSHlegELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSAL 604
Cdd:COG0497    212 EE--------ERRRLSNAEKLREALQEAL---EALSGGEGGALDLLGQALRALERLAEYDPSLAELAERLESALIELEEA 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  605 NEALA--LDKVGLNQQLLQLEEEnqsvcsRMEAAEQARNALQVDLAE----AEKRREALweknthleAQLQKAEEAGAEL 678
Cdd:COG0497    281 ASELRryLDSLEFDPERLEEVEE------RLALLRRLARKYGVTVEEllayAEELRAEL--------AELENSDERLEEL 346

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2217334288  679 QADLRDIQEEKEEIQKKLSESRHQ-----QEAATTQLEQL 713
Cdd:COG0497    347 EAELAEAEAELLEAAEKLSAARKKaakklEKAVTAELADL 386
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1010-1462 2.43e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 2.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1010 KQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLslMEKEQRLLVLQEADSIRQQELSALRQDM 1089
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEK--LEKLLQLLPLYQELEALEAELAELPERL 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1090 QEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAE 1169
Cdd:COG4717    149 EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1170 QQPGNQAQAQAQLASLYSALQQALGsvcesrpelsgggdSAPSVWGLEPDQNGARSLFKRGPLLTALsaeaVASALHKLH 1249
Cdd:COG4717    229 LEQLENELEAAALEERLKEARLLLL--------------IAAALLALLGLGGSLLSLILTIAGVLFL----VLGLLALLF 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1250 QDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRL 1329
Cdd:COG4717    291 LLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQ 370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1330 RRAELQRMEAQGERELLQAAKENLTAQVEhLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQG 1409
Cdd:COG4717    371 EIAALLAEAGVEDEEELRAALEQAEEYQE-LKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELE 449

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2217334288 1410 ELKVAQGKALQENLALLT-QTLAEREEEVETLRGQIQELEKQREMQKAALELLS 1462
Cdd:COG4717    450 ELREELAELEAELEQLEEdGELAELLQELEELKAELRELAEEWAALKLALELLE 503
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 934-1693 2.46e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.18  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  934 LLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRElKEAARQHRDDLAALQEESSSLLQDKMDLQKQVE 1013
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQME-RDAMADIRRRESQSQEDLRNQLQNTVHELEAAK 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1014 DLKSQLVaqDDSQRLVEQEVQEKLRETQEYNRIQKEL-EREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEA 1092
Cdd:pfam15921  159 CLKEDML--EDSNTQIEQLRKMMLSHEGVLQEIRSILvDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYL 236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1093 QGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELeashITEQQLRASLWAQEAKAAQLQlrLRSTESQLEaLAAEQQP 1172
Cdd:pfam15921  237 KGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQL----ISEHEVEITGLTEKASSARSQ--ANSIQSQLE-IIQEQAR 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1173 GNQAQAQAQLASLYSALQQALGSVCESRPELSGggdsapSVWGLEPDQNGARS-LFKRGPLLTALSAEA--VASALHKLH 1249
Cdd:pfam15921  310 NQNSMYMRQLSDLESTVSQLRSELREAKRMYED------KIEELEKQLVLANSeLTEARTERDQFSQESgnLDDQLQKLL 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1250 QDLWKTQQTRDVLRDQVQKLEERLTDTEaeksqvhTELQDLQRQLSQNQEEKSKWEGKQNSLESELM-ELHETMASLQSR 1328
Cdd:pfam15921  384 ADLHKREKELSLEKEQNKRLWDRDTGNS-------ITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGK 456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1329 LRRAE-LQRMEAQgerelLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQ-ALQ 1406
Cdd:pfam15921  457 NESLEkVSSLTAQ-----LESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDlKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1407 EQGELKVAQG--KALQENLALLTQTLAEREEEVETLRGQIQELEK-------------------QREMQKAALELLSLDL 1465
Cdd:pfam15921  532 ELQHLKNEGDhlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgqhgrtagamqvekaqlEKEINDRRLELQEFKI 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1466 KKRNQEVDLQQEQIQ----ELEKCRSV------LEHLPMAVQEREQKLT---VQREQIRELEKDRETQRNVLEHQLLELE 1532
Cdd:pfam15921  612 LKDKKDAKIRELEARvsdlELEKVKLVnagserLRAVKDIKQERDQLLNevkTSRNELNSLSEDYEVLKRNFRNKSEEME 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1533 KKDQMIESQRGQVQDLKKQlvTLECLALELEENHHKMECQQKLIKELEGQReTQRVALTHLTLDLEErsqELQAQSSQIH 1612
Cdd:pfam15921  692 TTTNKLKMQLKSAQSELEQ--TRNTLKSMEGSDGHAMKVAMGMQKQITAKR-GQIDALQSKIQFLEE---AMTNANKEKH 765

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1613 DLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLErrDQELMLQKERIQVLEDQRTRQtkilEEDLEQIKLSL 1692
Cdd:pfam15921  766 FLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVA--NMEVALDKASLQFAECQDIIQ----RQEQESVRLKL 839


                   .
gi 2217334288 1693 R 1693
Cdd:pfam15921  840 Q 840
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
789-1141 2.49e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 2.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  789 QLEVQIQTVTQAKEVIQGEVRCLK-----LELDTERSQAEQERDAAARQLAQAEQEGKT--ALEQQKAAHEKEVNQLREK 861
Cdd:COG4717     99 ELEEELEELEAELEELREELEKLEkllqlLPLYQELEALEAELAELPERLEELEERLEElrELEEELEELEAELAELQEE 178

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  862 WEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLL------ 935
Cdd:COG4717    179 LEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLliaaal 258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  936 ---------------------------------QTQKELADASQQLERLRQDMKVQKLKEQETTGILQtQLQEAQRELKE 982
Cdd:COG4717    259 lallglggsllsliltiagvlflvlgllallflLLAREKASLGKEAEELQALPALEELEEEELEELLA-ALGLPPDLSPE 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  983 AARQHRDDLAALQEESSSLLQDKMDLQ-KQVEDLKSQLVAQDDSQRlvEQEVQEKLRETQEYNRIQKELEREKASLTLSL 1061
Cdd:COG4717    338 ELLELLDRIEELQELLREAEELEEELQlEELEQEIAALLAEAGVED--EEELRAALEQAEEYQELKEELEELEEQLEELL 415

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1062 MEKEQRLLVLQEADsiRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRAS 1141
Cdd:COG4717    416 GELEELLEALDEEE--LEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWA 493
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
291-779 2.52e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 2.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  291 LLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQ----------EEKLSLQQVIKDITQVMVEEGDNIA 360
Cdd:COG4913    253 LLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELeelraelarlEAELERLEARLDALREELDELEAQI 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  361 QGSGHENSLELDSSIfsqfdyQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKl 440
Cdd:COG4913    333 RGNGGDRLEQLEREI------ERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEE- 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  441 tgERDTLAGQTVDLQGEVDSLSKERELLQK-----------AREELRQQLEV---------------LEQEAWRLrrvNV 494
Cdd:COG4913    406 --ALAEAEAALRDLRRELRELEAEIASLERrksniparllaLRDALAEALGLdeaelpfvgelievrPEEERWRG---AI 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  495 ELQLQG--------DSAQGQKEEQQEELHLAVR---ERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQ-- 561
Cdd:COG4913    481 ERVLGGfaltllvpPEHYAAALRWVNRLHLRGRlvyERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRfd 560

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  562 -EQTEVTAALARAEQSI--AELSSSENTL---KTEVADLRA------AAVKLSALNEALAldkvGLNQQLLQLEEENQSV 629
Cdd:COG4913    561 yVCVDSPEELRRHPRAItrAGQVKGNGTRhekDDRRRIRSRyvlgfdNRAKLAALEAELA----ELEEELAEAEERLEAL 636

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  630 CSRMEAAEQARNALQ---------VDLAEAEKRREALWEKNTHLEA---QLQKAEEAGAELQADLRDIQEEKEEIQKKLS 697
Cdd:COG4913    637 EAELDALQERREALQrlaeyswdeIDVASAEREIAELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIG 716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  698 ESRHQQEAATTQLEQLhqeAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQ 777
Cdd:COG4913    717 RLEKELEQAEEELDEL---QDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAM 793


                   ..
gi 2217334288  778 QQ 779
Cdd:COG4913    794 RA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 428-640 2.56e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  428 EEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQK 507
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  508 EEQQEEL--HLAVRERERLQEMLMGLEAKQS--ESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSS 583
Cdd:COG4942    100 EAQKEELaeLLRALYRLGRQPPLALLLSPEDflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217334288  584 ENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQAR 640
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
mukB PRK04863
chromosome partition protein MukB;
846-1169 2.66e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 2.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  846 QQKAAHEKEVNQLREKWEKERSWHQqELAKALESLEREKMELEMRLKE----QQTEMEAIQAQREEERTQAESALCQMQL 921
Cdd:PRK04863   286 EEALELRRELYTSRRQLAAEQYRLV-EMARELAELNEAESDLEQDYQAasdhLNLVQTALRQQEKIERYQADLEELEERL 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  922 ETEKERVSLL-ETLLQTQKELADASQQLERLRQDMK--VQKLKEQETTGIlqtQLQEAQRELKEAARQ-HRDDLAAlqee 997
Cdd:PRK04863   365 EEQNEVVEEAdEQQEENEARAEAAEEEVDELKSQLAdyQQALDVQQTRAI---QYQQAVQALERAKQLcGLPDLTA---- 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  998 sssllqdkmdlqKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYN-----------RIQKELEREKASltlslmEKEQ 1066
Cdd:PRK04863   438 ------------DNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHsqfeqayqlvrKIAGEVSRSEAW------DVAR 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1067 RLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEaqlleELEASHITEQQLRASLWAQE 1146
Cdd:PRK04863   500 ELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDED-----ELEQLQEELEARLESLSESV 574

                          330       340
                   ....*....|....*....|...
gi 2217334288 1147 AKAAQLQLRLRSTESQLEALAAE 1169
Cdd:PRK04863   575 SEARERRMALRQQLEQLQARIQR 597
mukB PRK04863
chromosome partition protein MukB;
250-1087 2.79e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  250 LAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRE----------TVEILETN 319
Cdd:PRK04863   364 LEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERakqlcglpdlTADNAEDW 443

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  320 HTELM--EHEASLSRNAQEEKLSLQQVIKDItqvmveegdniaqgsgHENSLELDSSIFSQFDYQDA-DKALTLVRSVLT 396
Cdd:PRK04863   444 LEEFQakEQEATEELLSLEQKLSVAQAAHSQ----------------FEQAYQLVRKIAGEVSRSEAwDVARELLRRLRE 507

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  397 RRRQA--VQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQkltgERDTLAGQTVDLQGEVDSLSKERELLQKAREE 474
Cdd:PRK04863   508 QRHLAeqLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLD----DEDELEQLQEELEARLESLSESVSEARERRMA 583

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  475 LRQQLEVLEQEAWRLRRVNVELQLQGDSAqgqkeeqqeelhlavrerERLQEMlMGLEAKQSESLSELItlrealeSSHL 554
Cdd:PRK04863   584 LRQQLEQLQARIQRLAARAPAWLAAQDAL------------------ARLREQ-SGEEFEDSQDVTEYM-------QQLL 637

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  555 EGEL-LRQEQTEVTAALARAEQSIAELSSSENTLKTEVADL--RAAAVKLSALNEALALDKVGLNQQLLQleeenqsvcs 631
Cdd:PRK04863   638 EREReLTVERDELAARKQALDEEIERLSQPGGSEDPRLNALaeRFGGVLLSEIYDDVSLEDAPYFSALYG---------- 707

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  632 rmeaaeQARNALQV-DLAEAEKRREALWEKNTHL---EAQLQKAEEAGAELQADLRDIQEEKEEIQKKLS----ESRHQQ 703
Cdd:PRK04863   708 ------PARHAIVVpDLSDAAEQLAGLEDCPEDLyliEGDPDSFDDSVFSVEELEKAVVVKIADRQWRYSrfpeVPLFGR 781

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  704 EAATTQLEQLHQEAkrqeevlaravqekEALVREKAALEVRLQAVERDRQDLaEQLQGLSSAKELL---ESSLFEAQQQN 780
Cdd:PRK04863   782 AAREKRIEQLRAER--------------EELAERYATLSFDVQKLQRLHQAF-SRFIGSHLAVAFEadpEAELRQLNRRR 846

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  781 SVIEVTKGQLEVQIQTVT----QAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAH--EKE 854
Cdd:PRK04863   847 VELERALADHESQEQQQRsqleQAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEAEEAKRFVQQHGNALAqlEPI 926

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  855 VNQLREKWEK-ERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQRE-EERTQAESALCQMQLETEKERVSLLE 932
Cdd:PRK04863   927 VSVLQSDPEQfEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFSYEDAAEMlAKNSDLNEKLRQRLEQAEQERTRARE 1006

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  933 TLLQTQKELADASQQLERLRQ--DMKVQKLKEqettgiLQTQLQE----AQRELKEAARQHRDDLaalQEESSSLLQDKM 1006
Cdd:PRK04863  1007 QLRQAQAQLAQYNQVLASLKSsyDAKRQMLQE------LKQELQDlgvpADSGAEERARARRDEL---HARLSANRSRRN 1077

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1007 DLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRE-TQEYNRIQKELEREKASLTLS-LMEKEQRLLVLQEADSIRQQELSA 1084
Cdd:PRK04863  1078 QLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQvVNAKAGWCAVLRLVKDNGVERrLHRRELAYLSADELRSMSDKALGA 1157


                   ...
gi 2217334288 1085 LRQ 1087
Cdd:PRK04863  1158 LRL 1160
PTZ00491 PTZ00491
major vault protein; Provisional
 824-944 2.92e-03

major vault protein; Provisional


Pssm-ID: 240439 [Multi-domain]  Cd Length: 850  Bit Score: 43.08  E-value: 2.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  824 QERDAAARQLAQA-EQEGKTALEQQKAAHEKEVNQLREKWEKERSwHQQELAKALESLEREKMELEMRLKEQQTEMEAIQ 902
Cdd:PTZ00491   662 KSQEAAARHQAELlEQEARGRLERQKMHDKAKAEEQRTKLLELQA-ESAAVESSGQSRAEALAEAEARLIEAEAEVEQAE 740

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 2217334288  903 AQREEERTQAESALCQMQLETEKE---RVSLLETLLQTQKELADA 944
Cdd:PTZ00491   741 LRAKALRIEAEAELEKLRKRQELEleyEQAQNELEIAKAKELADI 785
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 519-1169 2.96e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.04  E-value: 2.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  519 RERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAA 598
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  599 VKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQ-ARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAE 677
Cdd:pfam02463  260 IEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKsELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  678 LQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAE 757
Cdd:pfam02463  340 LEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLED 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  758 QLQGLSSAKELLESSLFEAqQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAE 837
Cdd:pfam02463  420 LLKEEKKEELEILEEEEES-IELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEER 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  838 QEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALC 917
Cdd:pfam02463  499 SQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGAR 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  918 QMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEE 997
Cdd:pfam02463  579 KLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGL 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  998 SSSLLQDKMDLQKQVEDLKSQLVAQDdsqrlvEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSI 1077
Cdd:pfam02463  659 AEKSEVKASLSELTKELLEIQELQEK------AESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1078 RQQELSALRQdMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLR 1157
Cdd:pfam02463  733 KINEELKLLK-QKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK 811

                          650
                   ....*....|..
gi 2217334288 1158 STESQLEALAAE 1169
Cdd:pfam02463  812 EEAELLEEEQLL 823
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 670-994 3.09e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 42.92  E-value: 3.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  670 KAEEAGAelqADLRDIQEEKEEIQKKLSESRHQ-----QEAATTQLEQLHQEAKRQ--EEVLARAVQEKEALVREKAAle 742
Cdd:PLN03229   422 KKREAVK---TPVRELEGEVEKLKEQILKAKESsskpsELALNEMIEKLKKEIDLEytEAVIAMGLQERLENLREEFS-- 496

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  743 vrlqavERDRQD------LAEQLQGLssaKELLESSLFEAQQQNSVievtKGQLEVqIQTVTQAKEVIQGEVRCLKLELD 816
Cdd:PLN03229   497 ------KANSQDqlmhpvLMEKIEKL---KDEFNKRLSRAPNYLSL----KYKLDM-LNEFSRAKALSEKKSKAEKLKAE 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  817 TERSQAEQERDAAARQLAQAEqegKTALEQQKAAHEKEVNQ-LREKWEKERSWHQQELAKALES--LEREKMELEMRLKE 893
Cdd:PLN03229   563 INKKFKEVMDRPEIKEKMEAL---KAEVASSGASSGDELDDdLKEKVEKMKKEIELELAGVLKSmgLEVIGVTKKNKDTA 639

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  894 QQTEMEAIQAQREEERTQAESALCQMQLETE-KERVSLL--ETLLQTQKELADASQQLERLRQdmkvqKLKEQETTGILQ 970
Cdd:PLN03229   640 EQTPPPNLQEKIESLNEEINKKIERVIRSSDlKSKIELLklEVAKASKTPDVTEKEKIEALEQ-----QIKQKIAEALNS 714

                          330       340
                   ....*....|....*....|....
gi 2217334288  971 TQLQEAQRELKEAARQHRDDLAAL 994
Cdd:PLN03229   715 SELKEKFEELEAELAAARETAAES 738
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 397-1160 3.31e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.02  E-value: 3.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  397 RRRQAVQDLRQQLAGCQEAVNLLQQQHdqweeegKALRQRLQKLTGERDTLagqTVDLQGEVDSLSKERELLQKAREELR 476
Cdd:COG3096    282 ELSERALELRRELFGARRQLAEEQYRL-------VEMARELEELSARESDL---EQDYQAASDHLNLVQTALRQQEKIER 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  477 QQLEVLEQEAwRLRrvnvELQLQGDSAQGQKEEQQEELHLAVRERERLQEML----MGLEAKQSESLS---ELITLREAL 549
Cdd:COG3096    352 YQEDLEELTE-RLE----EQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLadyqQALDVQQTRAIQyqqAVQALEKAR 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  550 ESSHLEGelLRQEQTEVTAALARAEQSiaELSSSENTLKTEVADLRAAAVKLSALNEALAL--------DKVGLNQQLLQ 621
Cdd:COG3096    427 ALCGLPD--LTPENAEDYLAAFRAKEQ--QATEEVLELEQKLSVADAARRQFEKAYELVCKiageversQAWQTARELLR 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  622 LEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAG---AELQADLRDIQEEKEEIQKKLSE 698
Cdd:COG3096    503 RYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEellAELEAQLEELEEQAAEAVEQRSE 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  699 SRHQQEAATTQLEQLHQEA----------KRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGL-SSAKE 767
Cdd:COG3096    583 LRQQLEQLRARIKELAARApawlaaqdalERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALeSQIER 662

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  768 LLESSLFEAQQQNSVIEVTKGQLEVQIQ---TVTQAK--EVIQGEVRCLKLELDTERSQA---------------EQERD 827
Cdd:COG3096    663 LSQPGGAEDPRLLALAERLGGVLLSEIYddvTLEDAPyfSALYGPARHAIVVPDLSAVKEqlagledcpedlyliEGDPD 742

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  828 AAARQLAQAEQEGKTALEQQ-----------------KAAHEKEVNQLREKWEK------ERSWHQQELAKALESLER-- 882
Cdd:COG3096    743 SFDDSVFDAEELEDAVVVKLsdrqwrysrfpevplfgRAAREKRLEELRAERDElaeqyaKASFDVQKLQRLHQAFSQfv 822

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  883 ---------EKMELEMR-LKEQQTEMEAIQAQREEERTQAESALCQMqleteKERVSLLETLLQTQKELADAS--QQLER 950
Cdd:COG3096    823 gghlavafaPDPEAELAaLRQRRSELERELAQHRAQEQQLRQQLDQL-----KEQLQLLNKLLPQANLLADETlaDRLEE 897

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  951 LRQDMkvqklkeqettgilqTQLQEAQRELK---EAARQHRDDLAALQ---EESSSLLQDKMDLQKQVEDLKSQLVA--- 1021
Cdd:COG3096    898 LREEL---------------DAAQEAQAFIQqhgKALAQLEPLVAVLQsdpEQFEQLQADYLQAKEQQRRLKQQIFAlse 962

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1022 ----------QDDSQRLVE-QEVQEKLRETQEynriQKELEREKASLTLSLMEKE--QRLLVLQEADSIRQqelsALRQD 1088
Cdd:COG3096    963 vvqrrphfsyEDAVGLLGEnSDLNEKLRARLE----QAEEARREAREQLRQAQAQysQYNQVLASLKSSRD----AKQQT 1034

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217334288 1089 MQEAQGEQKELSAQMEllrqevKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTE 1160
Cdd:COG3096   1035 LQELEQELEELGVQAD------AEAEERARIRRDELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAE 1100
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1495-1724 3.47e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1495 AVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQK 1574
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1575 LIKELEGQ--RETQRVALTHLTLDLEERSQELQAQSSQ--IHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLT 1650
Cdd:COG4942    101 AQKEELAEllRALYRLGRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1651 QDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGK-GPSKAQRGSL 1724
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPaAGFAALKGKL 255
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 518-886 3.58e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 42.36  E-value: 3.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  518 VRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAA 597
Cdd:pfam19220   40 LRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALREAEAAKEELRIELRDKTAQ 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  598 AvklsalnEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAE 677
Cdd:pfam19220  120 A-------EALERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQALSEEQAAELAE 192

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  678 LQADLRDIQEEKEEIQKKLSEsrhqQEAATTQLEQLHQEAKRQ-EEVLARAVQEKEALVREKAALEVRLQAVERDRQDLA 756
Cdd:pfam19220  193 LTRRLAELETQLDATRARLRA----LEGQLAAEQAERERAEAQlEEAVEAHRAERASLRMKLEALTARAAATEQLLAEAR 268

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  757 EQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKeviqgevrclkLELDTERSQAEQERDAAARQLAQA 836
Cdd:pfam19220  269 NQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQF-----------QEMQRARAELEERAEMLTKALAAK 337

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 2217334288  837 EQEGKTAlEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKME 886
Cdd:pfam19220  338 DAALERA-EERIASLSDRIAELTKRFEVERAALEQANRRLKEELQRERAE 386
46 PHA02562
endonuclease subunit; Provisional
 588-772 3.83e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 3.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  588 KTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRrEALWEKNTHL--- 664
Cdd:PHA02562   212 GENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKV-IKMYEKGGVCptc 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  665 -------EAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAAT---TQLEQLHQ-------EAKRQEEVLARA 727
Cdd:PHA02562   291 tqqisegPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLelkNKISTNKQslitlvdKAKKVKAAIEEL 370

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2217334288  728 VQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESS 772
Cdd:PHA02562   371 QAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGIVTDLLKDS 415
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1615-1708 4.13e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.54  E-value: 4.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1615 ESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQEL---------MLQKERIQVLEDqrtRQTKILEEDL 1685
Cdd:COG2433    398 EREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIerlerelseARSEERREIRKD---REISRLDREI 474

                           90       100
                   ....*....|....*....|....*.
gi 2217334288 1686 EQIKLSL---RERGRELTTQRQLMQE 1708
Cdd:COG2433    475 ERLERELeeeRERIEELKRKLERLKE 500
mukB PRK04863
chromosome partition protein MukB;
1860-2238 4.36e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.64  E-value: 4.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1860 ELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQ----------------CAEQAQEHEVETRA 1923
Cdd:PRK04863   280 ERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDyqaasdhlnlvqtalrQQEKIERYQADLEE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1924 LQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEAL-------GKAHAALQG--KEQHLLEQAELS-RS 1993
Cdd:PRK04863   360 LEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALdvqqtraIQYQQAVQAleRAKQLCGLPDLTaDN 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1994 LEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQ-----------EDVQQLQQALAQRDEELRHQQEREQLLE 2062
Cdd:PRK04863   440 AEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQlvrkiagevsrSEAWDVARELLRRLREQRHLAEQLQQLR 519

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2063 KSLAQRvqenmiqeKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQqrnnLEALphshktspmEEQSLKLD 2142
Cdd:PRK04863   520 MRLSEL--------EQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEAR----LESL---------SESVSEAR 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2143 SLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQAsVLERDSEQQRLQDELELTRRAL 2222
Cdd:PRK04863   579 ERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQ-LLERERELTVERDELAARKQAL 657

                          410
                   ....*....|....*...
gi 2217334288 2223 EK--ERLHSPGATSTAEL 2238
Cdd:PRK04863   658 DEeiERLSQPGGSEDPRL 675
mukB PRK04863
chromosome partition protein MukB;
713-1052 5.38e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 5.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  713 LHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESslfEAQQQNSVIEVTKgQLEV 792
Cdd:PRK04863   291 LRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEK---IERYQADLEELEE-RLEE 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  793 QIQTVTQAKEViqgevrclKLELDTERSQAEQERDAAARQLAQAEQegktALE-QQKAAheKEVNQLREKWEKERSW--- 868
Cdd:PRK04863   367 QNEVVEEADEQ--------QEENEARAEAAEEEVDELKSQLADYQQ----ALDvQQTRA--IQYQQAVQALERAKQLcgl 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  869 ---HQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEeRTQAESALCQMQLETEKER-----VSLLETLlQTQKE 940
Cdd:PRK04863   433 pdlTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQ-FEQAYQLVRKIAGEVSRSEawdvaRELLRRL-REQRH 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  941 LADASQQLErlrqdmkvQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLV 1020
Cdd:PRK04863   511 LAEQLQQLR--------MRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRM 582

                          330       340       350
                   ....*....|....*....|....*....|..
gi 2217334288 1021 AQDDSQRLVEQEVQEKLRETQEYNRIQKELER 1052
Cdd:PRK04863   583 ALRQQLEQLQARIQRLAARAPAWLAAQDALAR 614
PTZ00121 PTZ00121
MAEBL; Provisional
 1275-2036 5.62e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.05  E-value: 5.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1275 DTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRME----AQGERELLQAAK 1350
Cdd:PTZ00121  1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEearkAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1351 ENLTAQVEHLQAAVVEARAQASAAGI---------LEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQE 1421
Cdd:PTZ00121  1160 AEDARKAEEARKAEDAKKAEAARKAEevrkaeelrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1422 NLAlltqtlaeREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEhlpMAVQEREQ 1501
Cdd:PTZ00121  1240 EEA--------KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEE---KKKADEAK 1308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1502 KLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLvtlECLALELEENHHKMECQQKLIKELEG 1581
Cdd:PTZ00121  1309 KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEA---EAAEEKAEAAEKKKEEAKKKADAAKK 1385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1582 QRETQRVALthltlDLEERSQELQAQSSQIHDLESHSTVlARELQERDQEVKsqreQIEELQRQKEHltqdlERRDQELM 1661
Cdd:PTZ00121  1386 KAEEKKKAD-----EAKKKAEEDKKKADELKKAAAAKKK-ADEAKKKAEEKK----KADEAKKKAEE-----AKKADEAK 1450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1662 LQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVEcQ 1741
Cdd:PTZ00121  1451 KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-K 1529

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1742 QEHIHELQELKDQLEQQLQGLHRKVGEtsllLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEA 1821
Cdd:PTZ00121  1530 AEEAKKADEAKKAEEKKKADELKKAEE----LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1822 LQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEElavegRRVQALEEVlgdlRAESREQEK 1901
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEE-----NKIKAAEEA----KKAEEDKKK 1676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1902 AllalqqqcaEQAQEHEVETRALQDSwLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAhaalQGKE 1981
Cdd:PTZ00121  1677 A---------EEAKKAEEDEKKAAEA-LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE----AEED 1742

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288 1982 QHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQED 2036
Cdd:PTZ00121  1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1835-2057 5.91e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 5.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1835 RVKEKADALQGALEqahmTLKERHGELQDHKEQARRLE------EELAVEGRRVQALEEVLGDLRAESREQEKALLAlqq 1908
Cdd:COG4913    222 DTFEAADALVEHFD----DLERAHEALEDAREQIELLEpirelaERYAAARERLAELEYLRAALRLWFAQRRLELLE--- 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1909 qcaEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAAraraeaLQEALGKAHAALQGKEQHLLEQA 1988
Cdd:COG4913    295 ---AELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQ------LEREIERLERELEERERRRARLE 365

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217334288 1989 ELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQER 2057
Cdd:COG4913    366 ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1572-1835 6.04e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 6.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1572 QQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQR-QKEHLT 1650
Cdd:pfam17380  280 HQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERiRQEERK 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1651 QDLER-RDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKL 1729
Cdd:pfam17380  360 RELERiRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRR 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1730 ILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQR----EQEIVVLQQQLQEARE---QGELKEQSLQ 1802
Cdd:pfam17380  440 LEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRkraeEQRRKILEKELEERKQamiEEERKRKLLE 519

                          250       260       270
                   ....*....|....*....|....*....|...
gi 2217334288 1803 SQLDEAQRALAQRDQELEALQQEQQQAQGQEER 1835
Cdd:pfam17380  520 KEMEERQKAIYEEERRREAEEERRKQQEMEERR 552
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 825-1479 6.77e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 6.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  825 ERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSwhQQELAKALESLE------------REKM------- 885
Cdd:COG3096    279 ERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSAR--ESDLEQDYQAASdhlnlvqtalrqQEKIeryqedl 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  886 -ELEMRLKEQQTEMEAIQAQREEERTQAESAlcQMQLETEKERVSLLETLLQTQKELADASQQ-LERLRQDMKVQKLKE- 962
Cdd:COG3096    357 eELTERLEEQEEVVEEAAEQLAEAEARLEAA--EEEVDSLKSQLADYQQALDVQQTRAIQYQQaVQALEKARALCGLPDl 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  963 -----QETTGILQTQLQEAQREL----------KEAARQHRDDLAALQ------------EESSSLLQDKMDLQ---KQV 1012
Cdd:COG3096    435 tpenaEDYLAAFRAKEQQATEEVleleqklsvaDAARRQFEKAYELVCkiageversqawQTARELLRRYRSQQalaQRL 514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1013 EDLKSQLvaQDDSQRLVEQEVQEKLREtqEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEA 1092
Cdd:COG3096    515 QQLRAQL--AELEQRLRQQQNAERLLE--EFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQL 590

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1093 QGEQKELSAQ----------MELLRQEVKEKEAD---FLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRST 1159
Cdd:COG3096    591 RARIKELAARapawlaaqdaLERLREQSGEALADsqeVTAAMQQLLEREREATVERDELAARKQALESQIERLSQPGGAE 670

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1160 ESQLEALA--------AEQQPGNQAQAQAQLASLYSALQQAL--GSVCESRPELSGGGDSAPSVWGLEPD---------- 1219
Cdd:COG3096    671 DPRLLALAerlggvllSEIYDDVTLEDAPYFSALYGPARHAIvvPDLSAVKEQLAGLEDCPEDLYLIEGDpdsfddsvfd 750

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1220 ----------QNGAR----SLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLT----------- 1274
Cdd:COG3096    751 aeeledavvvKLSDRqwrySRFPEVPLFGRAAREKRLEELRAERDELAEQYAKASFDVQKLQRLHQAFSqfvgghlavaf 830

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1275 --DTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETM--------ASLQSRLRRAELQRMEAQGERE 1344
Cdd:COG3096    831 apDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLpqanlladETLADRLEELREELDAAQEAQA 910

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1345 LLQAAKENLT-------------AQVEHLQAAVVEARAQ-----------------------ASAAGILEEDlRTARSAL 1388
Cdd:COG3096    911 FIQQHGKALAqleplvavlqsdpEQFEQLQADYLQAKEQqrrlkqqifalsevvqrrphfsyEDAVGLLGEN-SDLNEKL 989

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1389 KLKNEEVESERERA------------QALQEQGELKVAQGkALQENLALLTQTLA-------------------EREEEV 1437
Cdd:COG3096    990 RARLEQAEEARREAreqlrqaqaqysQYNQVLASLKSSRD-AKQQTLQELEQELEelgvqadaeaeerarirrdELHEEL 1068

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 2217334288 1438 ETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQI 1479
Cdd:COG3096   1069 SQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQV 1110
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 502-699 6.86e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 6.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  502 SAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELS 581
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  582 SSENTLKTEVADLRAAAVKLSALN--------------------------------EALALDKVGLNQQLLQLEEENQSV 629
Cdd:COG4942     97 AELEAQKEELAELLRALYRLGRQPplalllspedfldavrrlqylkylaparreqaEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  630 CSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSES 699
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
785-952 7.37e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.19  E-value: 7.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  785 VTKGQLEVQIQTVtqakeviqgevrclklELDTERSQAEQERDAAARQLAQAEQEgkTALEQQKAAHEKEVNQLREKWEK 864
Cdd:COG1566     67 VKKGQVLARLDPT----------------DLQAALAQAEAQLAAAEAQLARLEAE--LGAEAEIAAAEAQLAAAQAQLDL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  865 erswhQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESAlcQMQLETEKERVSLLETLLQTQKELADA 944
Cdd:COG1566    129 -----AQRELERYQALYKKGAVSQQELDEARAALDAAQAQLEAAQAQLAQA--QAGLREEEELAAAQAQVAQAEAALAQA 201


                   ....*...
gi 2217334288  945 SQQLERLR 952
Cdd:COG1566    202 ELNLARTT 209
PRK12704 PRK12704
phosphodiesterase; Provisional
 1023-1169 7.47e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 7.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1023 DDSQRLVEQEVQEKLRETQ-EYNRIQKELEREKASLTLSLMEKEQRLlvLQEADSIRqQELSALRQDMQEAQGEQKELSA 1101
Cdd:PRK12704    45 EEAKKEAEAIKKEALLEAKeEIHKLRNEFEKELRERRNELQKLEKRL--LQKEENLD-RKLELLEKREEELEKKEKELEQ 121

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217334288 1102 QMEllrqEVKEKEADFLAQEAQLLEELEasHIteqqlrASLWAQEAKaaqlQLRLRSTESQLEALAAE 1169
Cdd:PRK12704   122 KQQ----ELEKKEEELEELIEEQLQELE--RI------SGLTAEEAK----EILLEKVEEEARHEAAV 173
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 797-926 7.81e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.35  E-value: 7.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  797 VTQAKEVIQGEVrcLKLE-----LDTERSQAEQERDAAARQLAQAEQEgKTALEQQKaahekevNQLREKWEKERSWHQQ 871
Cdd:PRK00409   504 IEEAKKLIGEDK--EKLNeliasLEELERELEQKAEEAEALLKEAEKL-KEELEEKK-------EKLQEEEDKLLEEAEK 573

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2217334288  872 ELAKALESLEREKMELEMRLKEQQTEMEAiqAQREEERTQAESALCQMQLETEKE 926
Cdd:PRK00409   574 EAQQAIKEAKKEADEIIKELRQLQKGGYA--SVKAHELIEARKRLNKANEKKEKK 626
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1407-1793 8.69e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 8.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1407 EQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKR--NQEVDLQQEQIQELEK 1484
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEalEAELAELPERLEELEE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1485 CRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQrnvlehQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEE 1564
Cdd:COG4717    154 RLEELRELEEELEELEAELAELQEELEELLEQLSLA------TEEELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1565 NHHKMECQQKLIKELEGQRETQRVALTH-LTLDLEERSQELQAQSSQIHDLeshSTVLARELQERDQEVKSQREQIEELQ 1643
Cdd:COG4717    228 ELEQLENELEAAALEERLKEARLLLLIAaALLALLGLGGSLLSLILTIAGV---LFLVLGLLALLFLLLAREKASLGKEA 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1644 RQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERgRELTTQRQLMQERAEEGKGPSKAQRGS 1723
Cdd:COG4717    305 EELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREA-EELEEELQLEELEQEIAALLAEAGVED 383

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1724 LEhmklILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSllLSQREQEIVVLQQQLQEAREQ 1793
Cdd:COG4717    384 EE----ELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALD--EEELEEELEELEEELEELEEE 447
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1577-2223 9.17e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.49  E-value: 9.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1577 KELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEElQRQKEHLTQDLERR 1656
Cdd:TIGR00618  190 KSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE-QLKKQQLLKQLRAR 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1657 DQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSL--RERGRELTTQRQLMQERAEE--GKGPSKAQRGSLEHMKLILR 1732
Cdd:TIGR00618  269 IEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQieQQAQRIHTELQSKMRSRAKLlmKRAAHVKQQSSIEEQRRLLQ 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1733 DKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRAL 1812
Cdd:TIGR00618  349 TLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAH 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1813 AQRDQELEALQQEQQQAQGQEERVKEKADalQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDL 1892
Cdd:TIGR00618  429 AKKQQELQQRYAELCAAAITCTAQCEKLE--KIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPL 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1893 RAESREQEKALLALQqqcaeqaqehevETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALgk 1972
Cdd:TIGR00618  507 CGSCIHPNPARQDID------------NPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSF-- 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1973 ahAALQGKEQHLLEQAELSRSLEAStatLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQedvqqlqqalaqRDEELR 2052
Cdd:TIGR00618  573 --SILTQCDNRSKEDIPNLQNITVR---LQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQD------------VRLHLQ 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2053 HQQEREQLLEKSLAqrvqenmiQEKQNLGQEREEEEIRGLHQsVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTS 2132
Cdd:TIGR00618  636 QCSQELALKLTALH--------ALQLTLTQERVREHALSIRV-LPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLL 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 2133 PMEEQSLKLDSlepRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLE-RDSEQQRL 2211
Cdd:TIGR00618  707 RELETHIEEYD---REFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALqTGAELSHL 783

                          650
                   ....*....|..
gi 2217334288 2212 QDELELTRRALE 2223
Cdd:TIGR00618  784 AAEIQFFNRLRE 795
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 693-1051 9.31e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 9.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  693 QKKLSEsRHQQEaattQLEQLHQEAKRQE-EVLARAVQEKEALVREKAAlevRLQAVERDRQDLAEQLQ-GLSSAKELLE 770
Cdd:pfam17380  281 QKAVSE-RQQQE----KFEKMEQERLRQEkEEKAREVERRRKLEEAEKA---RQAEMDRQAAIYAEQERmAMERERELER 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  771 SSLFEAQQQNSviEVTKGQLEVQIQTVTqakeviqgEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKaa 850
Cdd:pfam17380  353 IRQEERKRELE--RIRQEEIAMEISRMR--------ELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKV-- 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  851 hekEVNQLREKWEKERswhQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQaesalcQMQLETEKERVSL 930
Cdd:pfam17380  421 ---EMEQIRAEQEEAR---QREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRK------KLELEKEKRDRKR 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288  931 LETLLQTQKEladasQQLERLRQDMkvqkLKEQETTGILQTQLQEAQRELKEAARQHrddlaalQEESSSLLQDKMDLQK 1010
Cdd:pfam17380  489 AEEQRRKILE-----KELEERKQAM----IEEERKRKLLEKEMEERQKAIYEEERRR-------EAEEERRKQQEMEERR 552

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 2217334288 1011 QVEDlKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELE 1051
Cdd:pfam17380  553 RIQE-QMRKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1255-1509 9.97e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 9.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1255 TQQTRDVLRDQVQKLEERLTDTEAEksqvhteLQDLQRQLsqnqeekskwegKQNSLESELMELHETMASLQSRLRRAEL 1334
Cdd:COG3206    173 ARKALEFLEEQLPELRKELEEAEAA-------LEEFRQKN------------GLVDLSEEAKLLLQQLSELESQLAEARA 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1335 QRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGiLEEDLRTARSALKLKNEEVESERERAQALQEQGElkva 1414
Cdd:COG3206    234 ELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAE-LEAELAELSARYTPNHPDVIALRAQIAALRAQLQ---- 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217334288 1415 qgkalqenlALLTQTLAEREEEVETLRGQIQELEKQREmqkaalellslDLKKRNQEVDLQQEQIQELEKCRSVLEHLPM 1494
Cdd:COG3206    309 ---------QEAQRILASLEAELEALQAREASLQAQLA-----------QLEARLAELPELEAELRRLEREVEVARELYE 368

                          250
                   ....*....|....*
gi 2217334288 1495 AVQEREQKLTVQREQ 1509
Cdd:COG3206    369 SLLQRLEEARLAEAL 383
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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