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Concise Results
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Full Results
alanine--tRNA ligase, cytoplasmic isoform X1 [Homo sapiens]
Protein Classification
alanine--tRNA ligase ( domain architecture ID 1001926 )
alanine--tRNA ligase catalyzes the attachment of alanine to the 3' OH group of ribose of tRNA(Ala)
List of domain hits
Name
Accession
Description
Interval
E-value
PLN02900 super family
cl33594 alanyl-tRNA synthetase
6-663
0e+00
alanyl-tRNA synthetase
PLN02900 :Pssm-ID: 215487 [Multi-domain]
Cd Length: 936
Bit Score: 987.20
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 6 TASE IR QR F ID FF KRNE HT YVH SS ATI P L DDPTLLF A NAGMNQFKPIFL N T I DP SH P MA KL S RA A NTQKCIRAGGKHNDL 85
Cdd:PLN02900 12 PGDR IR RT F LS FF ESKG HT FLP SS PLV P V DDPTLLF T NAGMNQFKPIFL G T A DP NT P LR KL P RA T NTQKCIRAGGKHNDL 91
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 86 DDVGKD V YHHTFFEMLG S WSFGDYFK EL A CKM A L ELLT QEF G I P IE RLY V TYFGGDE A ag LEA D L E CKQ IW QNL g L DDTK 165
Cdd:PLN02900 92 DDVGKD T YHHTFFEMLG N WSFGDYFK KE A IGW A W ELLT KVY G L P AD RLY A TYFGGDE K -- QAP D D E ARA IW LDY - L PEER 168
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 166 I LP GNM KDNFWEMGDTGPCGPCSEIHYDRIG G RDAA H LVN Q DDP NVL EIWNLVFIQ Y NREADG I LKPLP K K SI DTGMGLE 245
Cdd:PLN02900 169 V LP FGC KDNFWEMGDTGPCGPCSEIHYDRIG E RDAA D LVN N DDP RFI EIWNLVFIQ F NREADG S LKPLP A K HV DTGMGLE 248
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 246 RL V S V LQNK M SNYDTDLF V P Y F E AIQ KG TGARPY T GKVGAED A D GI DMAYRV L ADH A RT ITV A L ADG GR P D N T GRGYVLR 325
Cdd:PLN02900 249 RL A S I LQNK P SNYDTDLF M P I F D AIQ EA TGARPY A GKVGAED D D RV DMAYRV V ADH I RT LSF A I ADG VV P S N E GRGYVLR 328
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 326 R I LRRAVRY AHEK L N A SR GFF AT LV D VVV QSL GD A FPE L KK DPDMVKD II N EEE VQ F L KTL SR G RRILDRKIQSLGDS -- 403
Cdd:PLN02900 329 R L LRRAVRY GRLL L G A EE GFF PA LV E VVV ELS GD V FPE V KK NEKRITE II A EEE LS F G KTL EK G IEKFKKALAAAKAN gg 408
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 404 KTIP G DT A W LLYDTYGFPVDLT G L I AEE K G LV VDM D GFE EERKL A QLK S Q -- GKG AGG EDLIM l DIY A IEE L RAR G LEV T 481
Cdd:PLN02900 409 PVLS G KD A F LLYDTYGFPVDLT E L M AEE R G VT VDM E GFE AAMEE A RER S R aa HLK AGG GAIEL - AAE A TSW L QKQ G VAA T 487
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 482 DD SP KY NYHL D SS gsyvfentv A T V M A LRREKM FVE E VS T G Q E C G V VLDKT C FYAE Q GGQI Y D E G Y L V kvdds SEDKTEF 561
Cdd:PLN02900 488 DD FL KY DWLS D HE --------- A V V K A ILTGGG FVE S VS E G D E V G I VLDKT S FYAE S GGQI G D T G V L E ----- GSGGAVV 553
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 562 T V KNA Q VR GG Y VLHIGT IY - G DLK VGD Q V WLFI D EP RRR P I MS NHTATH I LN F AL RS VLG E - A DQKGSLVA PDR LRFDF T 639
Cdd:PLN02900 554 E V SDV Q KA GG F VLHIGT VT e G SVS VGD A V TCKV D YD RRR R I AP NHTATH L LN S AL KE VLG D h V DQKGSLVA FEK LRFDF S 633
650 660
....*....|....*....|....
gi 2217304800 640 AKGA M STQQIKKA E EIA NE M I EA A 663
Cdd:PLN02900 634 HGKP M TPEELREV E SLV NE W I GD A 657
Name
Accession
Description
Interval
E-value
PLN02900
PLN02900 alanyl-tRNA synthetase
6-663
0e+00
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain]
Cd Length: 936
Bit Score: 987.20
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 6 TASE IR QR F ID FF KRNE HT YVH SS ATI P L DDPTLLF A NAGMNQFKPIFL N T I DP SH P MA KL S RA A NTQKCIRAGGKHNDL 85
Cdd:PLN02900 12 PGDR IR RT F LS FF ESKG HT FLP SS PLV P V DDPTLLF T NAGMNQFKPIFL G T A DP NT P LR KL P RA T NTQKCIRAGGKHNDL 91
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 86 DDVGKD V YHHTFFEMLG S WSFGDYFK EL A CKM A L ELLT QEF G I P IE RLY V TYFGGDE A ag LEA D L E CKQ IW QNL g L DDTK 165
Cdd:PLN02900 92 DDVGKD T YHHTFFEMLG N WSFGDYFK KE A IGW A W ELLT KVY G L P AD RLY A TYFGGDE K -- QAP D D E ARA IW LDY - L PEER 168
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 166 I LP GNM KDNFWEMGDTGPCGPCSEIHYDRIG G RDAA H LVN Q DDP NVL EIWNLVFIQ Y NREADG I LKPLP K K SI DTGMGLE 245
Cdd:PLN02900 169 V LP FGC KDNFWEMGDTGPCGPCSEIHYDRIG E RDAA D LVN N DDP RFI EIWNLVFIQ F NREADG S LKPLP A K HV DTGMGLE 248
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 246 RL V S V LQNK M SNYDTDLF V P Y F E AIQ KG TGARPY T GKVGAED A D GI DMAYRV L ADH A RT ITV A L ADG GR P D N T GRGYVLR 325
Cdd:PLN02900 249 RL A S I LQNK P SNYDTDLF M P I F D AIQ EA TGARPY A GKVGAED D D RV DMAYRV V ADH I RT LSF A I ADG VV P S N E GRGYVLR 328
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 326 R I LRRAVRY AHEK L N A SR GFF AT LV D VVV QSL GD A FPE L KK DPDMVKD II N EEE VQ F L KTL SR G RRILDRKIQSLGDS -- 403
Cdd:PLN02900 329 R L LRRAVRY GRLL L G A EE GFF PA LV E VVV ELS GD V FPE V KK NEKRITE II A EEE LS F G KTL EK G IEKFKKALAAAKAN gg 408
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 404 KTIP G DT A W LLYDTYGFPVDLT G L I AEE K G LV VDM D GFE EERKL A QLK S Q -- GKG AGG EDLIM l DIY A IEE L RAR G LEV T 481
Cdd:PLN02900 409 PVLS G KD A F LLYDTYGFPVDLT E L M AEE R G VT VDM E GFE AAMEE A RER S R aa HLK AGG GAIEL - AAE A TSW L QKQ G VAA T 487
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 482 DD SP KY NYHL D SS gsyvfentv A T V M A LRREKM FVE E VS T G Q E C G V VLDKT C FYAE Q GGQI Y D E G Y L V kvdds SEDKTEF 561
Cdd:PLN02900 488 DD FL KY DWLS D HE --------- A V V K A ILTGGG FVE S VS E G D E V G I VLDKT S FYAE S GGQI G D T G V L E ----- GSGGAVV 553
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 562 T V KNA Q VR GG Y VLHIGT IY - G DLK VGD Q V WLFI D EP RRR P I MS NHTATH I LN F AL RS VLG E - A DQKGSLVA PDR LRFDF T 639
Cdd:PLN02900 554 E V SDV Q KA GG F VLHIGT VT e G SVS VGD A V TCKV D YD RRR R I AP NHTATH L LN S AL KE VLG D h V DQKGSLVA FEK LRFDF S 633
650 660
....*....|....*....|....
gi 2217304800 640 AKGA M STQQIKKA E EIA NE M I EA A 663
Cdd:PLN02900 634 HGKP M TPEELREV E SLV NE W I GD A 657
AlaS
COG0013 Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ...
5-663
0e+00
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain]
Cd Length: 880
Bit Score: 869.37
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 5 L T AS EIRQ R F I DFF KRNE HT Y V H SS ATI P LD DPTLLF A NAGM N QFKP I FL NTID P SH P makls RA ANT QKC I R A GGKHND 84
Cdd:COG0013 2 M T SA EIRQ K F L DFF ESKG HT I V P SS SLV P KN DPTLLF T NAGM V QFKP Y FL GQEK P PY P ----- RA TTS QKC V R T GGKHND 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 85 L DD VG KDVY HHTFFEMLG SW SFGDYFKE L A CKM A L ELLT QEF G I P I ERL Y VT YFGG D E aagl EA dlec KQ IW QNL - G LDD 163
Cdd:COG0013 77 L EN VG YTAR HHTFFEMLG NF SFGDYFKE E A IAW A W ELLT EVL G L P K ERL W VT VYED D D ---- EA ---- YD IW KKE i G VPE 148
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 164 TK I LPGNM KDNFWEMGDTGPCGPCSEI H YDR ---- I GG RDA ah LVNQ D DPNVL EIWNLVF I Q Y NR EA DG I L K PLPKK S ID 239
Cdd:COG0013 149 ER I IRLGK KDNFWEMGDTGPCGPCSEI F YDR gpey G GG PPG -- SPGE D GDRYI EIWNLVF M Q F NR DE DG T L T PLPKK N ID 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 240 TGMGLER LVS VLQ NKM SNY D TDLF V P YF EA IQKG TG A rpytg K V GA EDA D gi D MAY RV L ADH A R TITVAL ADG GR P D N T G 319
Cdd:COG0013 227 TGMGLER IAA VLQ GVH SNY E TDLF R P LI EA AAEL TG V ----- K Y GA DEE D -- D VSL RV I ADH I R AVAFLI ADG VL P S N E G 299
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 320 RGYVLRRILRRAVR YAH e K L NASRG F FAT LV D VVV QSL GDA F PELK KDPDMVKDIINE EE VQ FL K TL S RG RRI LD RK I QS 399
Cdd:COG0013 300 RGYVLRRILRRAVR HGR - L L GIKEP F LYK LV P VVV EEM GDA Y PELK EKQELIEKVLKA EE ER FL R TL E RG LKL LD EA I AK 378
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 400 L GD -- S K TIP G DT A WL LYDTYGFP V DLT GL IA E E K GL V VD MD GFE EE ---- R KL A QLKSQGK G AGGE D LI mldiya IE EL 473
Cdd:COG0013 379 L KA ag G K VLS G ED A FK LYDTYGFP L DLT EE IA R E R GL T VD EE GFE AA meeq R ER A RAAAKFS G DAAV D GV ------ WR EL 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 474 RAR G LEV tddspkynyhl DSS G s Y VFENTV A T V M AL RREKMF V EEVST G Q E CG VVLD K T C FYAE Q GGQ IY D E G YLVK vdd 553
Cdd:COG0013 453 LEE G GPT ----------- EFV G - Y DTLEAE A K V L AL VKDGEL V DSAKA G E E VE VVLD R T P FYAE S GGQ VG D T G TIEG --- 517
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 554 sse D KTE F T V KNA Q - VR GG YVL HIG TI - Y G D LKVGD Q V WLFI D EP RRR P I MS NH T ATH I L NF ALR S VLGE - AD Q K GSLVA 630
Cdd:COG0013 518 --- D GGV F E V TDT Q k PP GG LIV HIG KV e E G E LKVGD T V TAQV D AE RRR A I AR NH S ATH L L HA ALR E VLGE h VT Q A GSLVA 594
650 660 670
....*....|....*....|....*....|...
gi 2217304800 631 PDRLRFDF TAKG A MSTQQIKKA E EIA NE M I EAA 663
Cdd:COG0013 595 PDRLRFDF SHFE A LTPEELAEI E DLV NE K I REN 627
tRNA-synt_2c
pfam01411 tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ...
9-597
0e+00
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain]
Cd Length: 548
Bit Score: 835.39
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 9 EIRQ R F I DFF KRNE HT Y V H SS ATI P LD DPTLLF A NAGMNQFKPIFL NTID pshp MAKLS RA A N T QKCIRAG gkhn DL DD V 88
Cdd:pfam01411 1 EIRQ T F L DFF EKKG HT R V P SS PVV P RN DPTLLF T NAGMNQFKPIFL GGVA ---- KPPYN RA T N S QKCIRAG ---- DL EN V 72
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 89 G KDVY HHTFFEMLG SW SFGDYFKE L A CKM A L ELLT Q E F G I P I ERLYVT Y F GG D E aagleadl E CKQ IW QNL - G LDDTK IL 167
Cdd:pfam01411 73 G RTGR HHTFFEMLG NF SFGDYFKE E A IEY A W ELLT K E L G L P P ERLYVT V F EW D D -------- E AGP IW EKI v G GPEER IL 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 168 PGNM KDNFWEMGDTGPCGPCSEI H YDR --- IGG R D AAHLVNQ DD PNV LEIWNLVF I Q Y NRE A DG I LKPLPKKSIDTGMGL 244
Cdd:pfam01411 145 RFGD KDNFWEMGDTGPCGPCSEI D YDR gee IGG W D SGGTPTA DD DRF LEIWNLVF M Q F NRE N DG T LKPLPKKSIDTGMGL 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 245 ERLV S VLQ NKM SNYDTD L F V P YF E A I QKGT GAR P YT gkvgaed A D GI D M AYRV L ADH A R TI T V ALADG GR P D N T GRGYVL 324
Cdd:pfam01411 225 ERLV A VLQ DVR SNYDTD V F I P VI E L I EEIS GAR Y YT ------- V D ET D E AYRV I ADH T R AL T F ALADG VV P S N E GRGYVL 297
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 325 RRILRRAVR Y A H e KL NASRG F FAT LV DV VV QS LGDA F PELK K D P D MVKD I INE EE VQ F L KTL S RG R R I L D R K I QS L GD - S 403
Cdd:pfam01411 298 RRILRRAVR H A K - KL GLKEP F LYD LV PT VV EV LGDA Y PELK E D E D FIQE I LEL EE ER F A KTL E RG L R L L E R L I AK L KK g K 376
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 404 KT I PG DT A WL LYDTYGFPVDLT GL IAEE K GL V VDM D GFE EERKLAQLK S QGKGAGGED li M LD IY A IE EL R A rglev T DD 483
Cdd:pfam01411 377 KT L PG ED A FK LYDTYGFPVDLT KE IAEE R GL K VDM P GFE YAMVEQRER S KQAVKEKGE -- K LD VS A LK EL P A ----- T TE 449
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 484 SPK Y NYHLDS sgsyvfentv A TVM AL RREKM FV E EV ST GQE C GV V LD K T C FYAE Q GGQI Y D E GY LVK vddsse D KT EF T V 563
Cdd:pfam01411 450 FLG Y DDLESE ---------- A KIL AL PKDGE FV A EV LA GQE G GV I LD R T P FYAE S GGQI G D T GY IIG ------ D GG EF R V 513
570 580 590
....*....|....*....|....*....|....*
gi 2217304800 564 KNA Q VR GG Y V L H I G TI - Y G D LKVGD Q V WLF IDE P R 597
Cdd:pfam01411 514 TDV Q KY GG V V V H K G KL e S G K LKVGD K V IAV IDE D R 548
alaS
TIGR00344 alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ...
9-664
0e+00
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain]
Cd Length: 845
Bit Score: 713.77
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 9 EIRQ R F I DFFK RNE H TYVH S SATI P LD DPTLL FA NAGM N QFKPIF LNTID P SHP makls R AA N T Q K CIR A ggkh NDL DD V 88
Cdd:TIGR00344 1 EIRQ T F L DFFK EKG H QVIP S APLV P RN DPTLL LT NAGM A QFKPIF TGIVK P PSN ----- R LT N A Q P CIR L ---- NDL EN V 71
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 89 G KDVY HHT F FEMLG SW SFGDYFKE L A CKM A L ELLT QEF G IPI ERLYVT YFGG DE A A GL eadleckq IW QNL G LDDTK I LP 168
Cdd:TIGR00344 72 G RTAR HHT L FEMLG NF SFGDYFKE E A IAF A W ELLT EVL G LDK ERLYVT VYED DE E A YK -------- IW EKI G IPADR I IK 143
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 169 GNM KDNFW E MGD t GPCGPC S EI H YD RI GG RDAAH L V nq DDPNV LE I WNLVF I Q Y NR EA DG ILK PLPKK S IDTGMGLER L V 248
Cdd:TIGR00344 144 CDA KDNFW D MGD - GPCGPC T EI Y YD FV GG KPGEP L E -- ENDRY LE V WNLVF M Q F NR DP DG NYT PLPKK N IDTGMGLER F V 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 249 S VLQ NKMS NYDTD L F V P YF E A I QKG TG ARPYTGKV G AE D ADGID -- MAY RV L ADH A R T I TVA LADG GR P D N T GRGYVLRR 326
Cdd:TIGR00344 221 A VLQ GVPT NYDTD I F L P LI E K I EEI TG VKYDSNNA G IM D EKRVE dl RSL RV I ADH T R A I AFM LADG VV P S N E GRGYVLRR 300
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 327 IL RRA V R YAH e KL NASRG F FAT LV DVVVQS LGD AF PELK KDPDM V KD I INE EE VQ F L KTL S RG R R ILDRKIQSL G d S K TI 406
Cdd:TIGR00344 301 LI RRA L R HGK - KL GLKEA F LYK LV PTLIEV LGD YY PELK EKQEF V EQ I LEL EE ER F A KTL E RG L R LFEKLLKKT G - K K EL 378
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 407 P G DT A WL LYDTYGFPV D LT GL IAEE K GL V VDM D GFE EERKLAQLK S QGKGAGG E DL I M L diyaieelrarg LE V TDDSPK 486
Cdd:TIGR00344 379 D G ED A FK LYDTYGFPV E LT KE IAEE R GL T VDM P GFE ALMAEQRER S KQNSQFQ E QE I A L ------------ VN V YPATEF 446
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 487 YN Y H - L DSS gsyvfentv A T V MA L RREKMF VE EVST GQ ECG V V LD K T C FYAE Q GGQI Y D E GYL VK vddsse DKTE F T V KN 565
Cdd:TIGR00344 447 LG Y D d L EFE --------- A K V IG L FDDGYL VE QALA GQ SVY V I LD Q T P FYAE S GGQI G D T GYL IA ------ NDGK F R V VD 511
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 566 A Q VRG G Y V L H I G TIY - G D LKVGD Q V WLF IDE P RR RP IM S NH T ATH I L NF AL RS VLG E - AD Q K GSLV APDR LRFDF TAKG A 643
Cdd:TIGR00344 512 V Q KPN G V V F H F G EVE g G S LKVGD K V IAV IDE K RR FR IM R NH S ATH L L HA AL QK VLG N h VW Q A GSLV SFKK LRFDF SHFR A 591
650 660
....*....|....*....|.
gi 2217304800 644 MSTQQIKKA E EI ANE M I E A AK 664
Cdd:TIGR00344 592 LTREELEEI E DL ANE Q I L A NI 612
AlaRS_core
cd00673 Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ...
7-254
1.73e-140
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain]
Cd Length: 232
Bit Score: 411.75
E-value: 1.73e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 7 ASEIR QR F ID FF KRNE HT Y V H SS ATI P L DDPTLLF A NAGMNQFKPIFL NTID P SHP makls R AA N T QKCIRAG GKH N dld 86
Cdd:cd00673 1 ASEIR ET F LS FF EKKG HT R V P SS PVV P R DDPTLLF T NAGMNQFKPIFL GEVP P PAN ----- R LV N S QKCIRAG DID N --- 72
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 87 d VGK DVY HHTFFEMLG SW SFGDYFKE L A CKM A L ELLT QEF G I P IE RLYV TY F G GD eaaglea D L E CKQI W QNL GL DDTK I 166
Cdd:cd00673 73 - VGK TGR HHTFFEMLG NF SFGDYFKE E A IAF A W ELLT EVL G L P KD RLYV SV F E GD ------- D E E EAIW W WKI GL PGIR I 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 167 LPGNM KDNFWEMG DT GPCGPCSEI H YDR IGG RDAA H L V N Q DD PNV LEIWNLVF I QYNR E ADG ILK PLPKK SI DTGMGLER 246
Cdd:cd00673 145 ERIGF KDNFWEMG GN GPCGPCSEI F YDR GEE RDAA S L P N E DD DRY LEIWNLVF M QYNR D ADG TYR PLPKK IV DTGMGLER 224
....*...
gi 2217304800 247 LV S VLQ NK 254
Cdd:cd00673 225 LV W VLQ GV 232
Name
Accession
Description
Interval
E-value
PLN02900
PLN02900 alanyl-tRNA synthetase
6-663
0e+00
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain]
Cd Length: 936
Bit Score: 987.20
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 6 TASE IR QR F ID FF KRNE HT YVH SS ATI P L DDPTLLF A NAGMNQFKPIFL N T I DP SH P MA KL S RA A NTQKCIRAGGKHNDL 85
Cdd:PLN02900 12 PGDR IR RT F LS FF ESKG HT FLP SS PLV P V DDPTLLF T NAGMNQFKPIFL G T A DP NT P LR KL P RA T NTQKCIRAGGKHNDL 91
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 86 DDVGKD V YHHTFFEMLG S WSFGDYFK EL A CKM A L ELLT QEF G I P IE RLY V TYFGGDE A ag LEA D L E CKQ IW QNL g L DDTK 165
Cdd:PLN02900 92 DDVGKD T YHHTFFEMLG N WSFGDYFK KE A IGW A W ELLT KVY G L P AD RLY A TYFGGDE K -- QAP D D E ARA IW LDY - L PEER 168
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 166 I LP GNM KDNFWEMGDTGPCGPCSEIHYDRIG G RDAA H LVN Q DDP NVL EIWNLVFIQ Y NREADG I LKPLP K K SI DTGMGLE 245
Cdd:PLN02900 169 V LP FGC KDNFWEMGDTGPCGPCSEIHYDRIG E RDAA D LVN N DDP RFI EIWNLVFIQ F NREADG S LKPLP A K HV DTGMGLE 248
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 246 RL V S V LQNK M SNYDTDLF V P Y F E AIQ KG TGARPY T GKVGAED A D GI DMAYRV L ADH A RT ITV A L ADG GR P D N T GRGYVLR 325
Cdd:PLN02900 249 RL A S I LQNK P SNYDTDLF M P I F D AIQ EA TGARPY A GKVGAED D D RV DMAYRV V ADH I RT LSF A I ADG VV P S N E GRGYVLR 328
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 326 R I LRRAVRY AHEK L N A SR GFF AT LV D VVV QSL GD A FPE L KK DPDMVKD II N EEE VQ F L KTL SR G RRILDRKIQSLGDS -- 403
Cdd:PLN02900 329 R L LRRAVRY GRLL L G A EE GFF PA LV E VVV ELS GD V FPE V KK NEKRITE II A EEE LS F G KTL EK G IEKFKKALAAAKAN gg 408
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 404 KTIP G DT A W LLYDTYGFPVDLT G L I AEE K G LV VDM D GFE EERKL A QLK S Q -- GKG AGG EDLIM l DIY A IEE L RAR G LEV T 481
Cdd:PLN02900 409 PVLS G KD A F LLYDTYGFPVDLT E L M AEE R G VT VDM E GFE AAMEE A RER S R aa HLK AGG GAIEL - AAE A TSW L QKQ G VAA T 487
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 482 DD SP KY NYHL D SS gsyvfentv A T V M A LRREKM FVE E VS T G Q E C G V VLDKT C FYAE Q GGQI Y D E G Y L V kvdds SEDKTEF 561
Cdd:PLN02900 488 DD FL KY DWLS D HE --------- A V V K A ILTGGG FVE S VS E G D E V G I VLDKT S FYAE S GGQI G D T G V L E ----- GSGGAVV 553
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 562 T V KNA Q VR GG Y VLHIGT IY - G DLK VGD Q V WLFI D EP RRR P I MS NHTATH I LN F AL RS VLG E - A DQKGSLVA PDR LRFDF T 639
Cdd:PLN02900 554 E V SDV Q KA GG F VLHIGT VT e G SVS VGD A V TCKV D YD RRR R I AP NHTATH L LN S AL KE VLG D h V DQKGSLVA FEK LRFDF S 633
650 660
....*....|....*....|....
gi 2217304800 640 AKGA M STQQIKKA E EIA NE M I EA A 663
Cdd:PLN02900 634 HGKP M TPEELREV E SLV NE W I GD A 657
AlaS
COG0013 Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ...
5-663
0e+00
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain]
Cd Length: 880
Bit Score: 869.37
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 5 L T AS EIRQ R F I DFF KRNE HT Y V H SS ATI P LD DPTLLF A NAGM N QFKP I FL NTID P SH P makls RA ANT QKC I R A GGKHND 84
Cdd:COG0013 2 M T SA EIRQ K F L DFF ESKG HT I V P SS SLV P KN DPTLLF T NAGM V QFKP Y FL GQEK P PY P ----- RA TTS QKC V R T GGKHND 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 85 L DD VG KDVY HHTFFEMLG SW SFGDYFKE L A CKM A L ELLT QEF G I P I ERL Y VT YFGG D E aagl EA dlec KQ IW QNL - G LDD 163
Cdd:COG0013 77 L EN VG YTAR HHTFFEMLG NF SFGDYFKE E A IAW A W ELLT EVL G L P K ERL W VT VYED D D ---- EA ---- YD IW KKE i G VPE 148
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 164 TK I LPGNM KDNFWEMGDTGPCGPCSEI H YDR ---- I GG RDA ah LVNQ D DPNVL EIWNLVF I Q Y NR EA DG I L K PLPKK S ID 239
Cdd:COG0013 149 ER I IRLGK KDNFWEMGDTGPCGPCSEI F YDR gpey G GG PPG -- SPGE D GDRYI EIWNLVF M Q F NR DE DG T L T PLPKK N ID 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 240 TGMGLER LVS VLQ NKM SNY D TDLF V P YF EA IQKG TG A rpytg K V GA EDA D gi D MAY RV L ADH A R TITVAL ADG GR P D N T G 319
Cdd:COG0013 227 TGMGLER IAA VLQ GVH SNY E TDLF R P LI EA AAEL TG V ----- K Y GA DEE D -- D VSL RV I ADH I R AVAFLI ADG VL P S N E G 299
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 320 RGYVLRRILRRAVR YAH e K L NASRG F FAT LV D VVV QSL GDA F PELK KDPDMVKDIINE EE VQ FL K TL S RG RRI LD RK I QS 399
Cdd:COG0013 300 RGYVLRRILRRAVR HGR - L L GIKEP F LYK LV P VVV EEM GDA Y PELK EKQELIEKVLKA EE ER FL R TL E RG LKL LD EA I AK 378
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 400 L GD -- S K TIP G DT A WL LYDTYGFP V DLT GL IA E E K GL V VD MD GFE EE ---- R KL A QLKSQGK G AGGE D LI mldiya IE EL 473
Cdd:COG0013 379 L KA ag G K VLS G ED A FK LYDTYGFP L DLT EE IA R E R GL T VD EE GFE AA meeq R ER A RAAAKFS G DAAV D GV ------ WR EL 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 474 RAR G LEV tddspkynyhl DSS G s Y VFENTV A T V M AL RREKMF V EEVST G Q E CG VVLD K T C FYAE Q GGQ IY D E G YLVK vdd 553
Cdd:COG0013 453 LEE G GPT ----------- EFV G - Y DTLEAE A K V L AL VKDGEL V DSAKA G E E VE VVLD R T P FYAE S GGQ VG D T G TIEG --- 517
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 554 sse D KTE F T V KNA Q - VR GG YVL HIG TI - Y G D LKVGD Q V WLFI D EP RRR P I MS NH T ATH I L NF ALR S VLGE - AD Q K GSLVA 630
Cdd:COG0013 518 --- D GGV F E V TDT Q k PP GG LIV HIG KV e E G E LKVGD T V TAQV D AE RRR A I AR NH S ATH L L HA ALR E VLGE h VT Q A GSLVA 594
650 660 670
....*....|....*....|....*....|...
gi 2217304800 631 PDRLRFDF TAKG A MSTQQIKKA E EIA NE M I EAA 663
Cdd:COG0013 595 PDRLRFDF SHFE A LTPEELAEI E DLV NE K I REN 627
tRNA-synt_2c
pfam01411 tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ...
9-597
0e+00
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain]
Cd Length: 548
Bit Score: 835.39
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 9 EIRQ R F I DFF KRNE HT Y V H SS ATI P LD DPTLLF A NAGMNQFKPIFL NTID pshp MAKLS RA A N T QKCIRAG gkhn DL DD V 88
Cdd:pfam01411 1 EIRQ T F L DFF EKKG HT R V P SS PVV P RN DPTLLF T NAGMNQFKPIFL GGVA ---- KPPYN RA T N S QKCIRAG ---- DL EN V 72
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 89 G KDVY HHTFFEMLG SW SFGDYFKE L A CKM A L ELLT Q E F G I P I ERLYVT Y F GG D E aagleadl E CKQ IW QNL - G LDDTK IL 167
Cdd:pfam01411 73 G RTGR HHTFFEMLG NF SFGDYFKE E A IEY A W ELLT K E L G L P P ERLYVT V F EW D D -------- E AGP IW EKI v G GPEER IL 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 168 PGNM KDNFWEMGDTGPCGPCSEI H YDR --- IGG R D AAHLVNQ DD PNV LEIWNLVF I Q Y NRE A DG I LKPLPKKSIDTGMGL 244
Cdd:pfam01411 145 RFGD KDNFWEMGDTGPCGPCSEI D YDR gee IGG W D SGGTPTA DD DRF LEIWNLVF M Q F NRE N DG T LKPLPKKSIDTGMGL 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 245 ERLV S VLQ NKM SNYDTD L F V P YF E A I QKGT GAR P YT gkvgaed A D GI D M AYRV L ADH A R TI T V ALADG GR P D N T GRGYVL 324
Cdd:pfam01411 225 ERLV A VLQ DVR SNYDTD V F I P VI E L I EEIS GAR Y YT ------- V D ET D E AYRV I ADH T R AL T F ALADG VV P S N E GRGYVL 297
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 325 RRILRRAVR Y A H e KL NASRG F FAT LV DV VV QS LGDA F PELK K D P D MVKD I INE EE VQ F L KTL S RG R R I L D R K I QS L GD - S 403
Cdd:pfam01411 298 RRILRRAVR H A K - KL GLKEP F LYD LV PT VV EV LGDA Y PELK E D E D FIQE I LEL EE ER F A KTL E RG L R L L E R L I AK L KK g K 376
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 404 KT I PG DT A WL LYDTYGFPVDLT GL IAEE K GL V VDM D GFE EERKLAQLK S QGKGAGGED li M LD IY A IE EL R A rglev T DD 483
Cdd:pfam01411 377 KT L PG ED A FK LYDTYGFPVDLT KE IAEE R GL K VDM P GFE YAMVEQRER S KQAVKEKGE -- K LD VS A LK EL P A ----- T TE 449
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 484 SPK Y NYHLDS sgsyvfentv A TVM AL RREKM FV E EV ST GQE C GV V LD K T C FYAE Q GGQI Y D E GY LVK vddsse D KT EF T V 563
Cdd:pfam01411 450 FLG Y DDLESE ---------- A KIL AL PKDGE FV A EV LA GQE G GV I LD R T P FYAE S GGQI G D T GY IIG ------ D GG EF R V 513
570 580 590
....*....|....*....|....*....|....*
gi 2217304800 564 KNA Q VR GG Y V L H I G TI - Y G D LKVGD Q V WLF IDE P R 597
Cdd:pfam01411 514 TDV Q KY GG V V V H K G KL e S G K LKVGD K V IAV IDE D R 548
alaS
TIGR00344 alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ...
9-664
0e+00
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain]
Cd Length: 845
Bit Score: 713.77
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 9 EIRQ R F I DFFK RNE H TYVH S SATI P LD DPTLL FA NAGM N QFKPIF LNTID P SHP makls R AA N T Q K CIR A ggkh NDL DD V 88
Cdd:TIGR00344 1 EIRQ T F L DFFK EKG H QVIP S APLV P RN DPTLL LT NAGM A QFKPIF TGIVK P PSN ----- R LT N A Q P CIR L ---- NDL EN V 71
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 89 G KDVY HHT F FEMLG SW SFGDYFKE L A CKM A L ELLT QEF G IPI ERLYVT YFGG DE A A GL eadleckq IW QNL G LDDTK I LP 168
Cdd:TIGR00344 72 G RTAR HHT L FEMLG NF SFGDYFKE E A IAF A W ELLT EVL G LDK ERLYVT VYED DE E A YK -------- IW EKI G IPADR I IK 143
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 169 GNM KDNFW E MGD t GPCGPC S EI H YD RI GG RDAAH L V nq DDPNV LE I WNLVF I Q Y NR EA DG ILK PLPKK S IDTGMGLER L V 248
Cdd:TIGR00344 144 CDA KDNFW D MGD - GPCGPC T EI Y YD FV GG KPGEP L E -- ENDRY LE V WNLVF M Q F NR DP DG NYT PLPKK N IDTGMGLER F V 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 249 S VLQ NKMS NYDTD L F V P YF E A I QKG TG ARPYTGKV G AE D ADGID -- MAY RV L ADH A R T I TVA LADG GR P D N T GRGYVLRR 326
Cdd:TIGR00344 221 A VLQ GVPT NYDTD I F L P LI E K I EEI TG VKYDSNNA G IM D EKRVE dl RSL RV I ADH T R A I AFM LADG VV P S N E GRGYVLRR 300
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 327 IL RRA V R YAH e KL NASRG F FAT LV DVVVQS LGD AF PELK KDPDM V KD I INE EE VQ F L KTL S RG R R ILDRKIQSL G d S K TI 406
Cdd:TIGR00344 301 LI RRA L R HGK - KL GLKEA F LYK LV PTLIEV LGD YY PELK EKQEF V EQ I LEL EE ER F A KTL E RG L R LFEKLLKKT G - K K EL 378
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 407 P G DT A WL LYDTYGFPV D LT GL IAEE K GL V VDM D GFE EERKLAQLK S QGKGAGG E DL I M L diyaieelrarg LE V TDDSPK 486
Cdd:TIGR00344 379 D G ED A FK LYDTYGFPV E LT KE IAEE R GL T VDM P GFE ALMAEQRER S KQNSQFQ E QE I A L ------------ VN V YPATEF 446
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 487 YN Y H - L DSS gsyvfentv A T V MA L RREKMF VE EVST GQ ECG V V LD K T C FYAE Q GGQI Y D E GYL VK vddsse DKTE F T V KN 565
Cdd:TIGR00344 447 LG Y D d L EFE --------- A K V IG L FDDGYL VE QALA GQ SVY V I LD Q T P FYAE S GGQI G D T GYL IA ------ NDGK F R V VD 511
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 566 A Q VRG G Y V L H I G TIY - G D LKVGD Q V WLF IDE P RR RP IM S NH T ATH I L NF AL RS VLG E - AD Q K GSLV APDR LRFDF TAKG A 643
Cdd:TIGR00344 512 V Q KPN G V V F H F G EVE g G S LKVGD K V IAV IDE K RR FR IM R NH S ATH L L HA AL QK VLG N h VW Q A GSLV SFKK LRFDF SHFR A 591
650 660
....*....|....*....|.
gi 2217304800 644 MSTQQIKKA E EI ANE M I E A AK 664
Cdd:TIGR00344 592 LTREELEEI E DL ANE Q I L A NI 612
AlaRS_core
cd00673 Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ...
7-254
1.73e-140
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain]
Cd Length: 232
Bit Score: 411.75
E-value: 1.73e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 7 ASEIR QR F ID FF KRNE HT Y V H SS ATI P L DDPTLLF A NAGMNQFKPIFL NTID P SHP makls R AA N T QKCIRAG GKH N dld 86
Cdd:cd00673 1 ASEIR ET F LS FF EKKG HT R V P SS PVV P R DDPTLLF T NAGMNQFKPIFL GEVP P PAN ----- R LV N S QKCIRAG DID N --- 72
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 87 d VGK DVY HHTFFEMLG SW SFGDYFKE L A CKM A L ELLT QEF G I P IE RLYV TY F G GD eaaglea D L E CKQI W QNL GL DDTK I 166
Cdd:cd00673 73 - VGK TGR HHTFFEMLG NF SFGDYFKE E A IAF A W ELLT EVL G L P KD RLYV SV F E GD ------- D E E EAIW W WKI GL PGIR I 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 167 LPGNM KDNFWEMG DT GPCGPCSEI H YDR IGG RDAA H L V N Q DD PNV LEIWNLVF I QYNR E ADG ILK PLPKK SI DTGMGLER 246
Cdd:cd00673 145 ERIGF KDNFWEMG GN GPCGPCSEI F YDR GEE RDAA S L P N E DD DRY LEIWNLVF M QYNR D ADG TYR PLPKK IV DTGMGLER 224
....*...
gi 2217304800 247 LV S VLQ NK 254
Cdd:cd00673 225 LV W VLQ GV 232
PRK01584
PRK01584 alanyl-tRNA synthetase; Provisional
5-662
3.27e-133
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain]
Cd Length: 594
Bit Score: 406.47
E-value: 3.27e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 5 L T AS E I R QRF IDFFK RNE H TYVHSSAT IP LD DPT L LF AN AGM NQFK P IF L NTID PS H pmakl S R AANT QKC I R A G gkhn D 84
Cdd:PRK01584 1 M T LD E L R KKY IDFFK SKG H VEIAGKSL IP EN DPT V LF TT AGM HPLV P YL L GEPH PS G ----- T R LVDV QKC L R T G ---- D 71
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 85 L D D VG k D VY H H TFFEMLG S WS F G D YFKE LAC K MAL E L LT QE -- FG IP IER LYVT Y F G GDE AA gl EA D L E CKQI W QN LG LD 162
Cdd:PRK01584 72 I D E VG - D LS H L TFFEMLG N WS L G A YFKE ESI K YSF E F LT SP dy LN IP KDK LYVT V F E GDE EI -- PR D E E TASV W ES LG IP 148
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 163 DTK I LPGNMKD N F W - EM G D TGPCGP CS EI HY D R ig G RDAAH lv NQDD P NV ----- L EIWN L VF I QYN REA DG ILKP L PK K 236
Cdd:PRK01584 149 KDR I FYLSREH N W W g PV G E TGPCGP DT EI FV D T -- G KPKCS -- VNCR P TC scgky F EIWN N VF M QYN KDE DG NYEE L KR K 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 237 SI DTGMG L ER LVSV LQ N K M S N YDT DL F V P YFEA I Q K GT G AR pytgkvg AEDADGI D MAY R VL ADH A R TITVA L A D -- GGR 314
Cdd:PRK01584 225 CV DTGMG I ER TIAF LQ G K S S V YDT EA F T P IIKR I E K IS G KI ------- YGQNEED D RSI R II ADH I R AACFI L G D pf VVL 297
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 315 P D N T G R GYVLRR IL RR AV R Y A h E KL NASRG F F A T LVD V V VQSL G DAF PEL KKDP D MV K DII N E EE VQ F L KTL SR G RRILD 394
Cdd:PRK01584 298 P S N V G Q GYVLRR LI RR SI R H A - K KL GIESH F L A D LVD S V EEIY G SFY PEL TEKK D FI K EEL N K EE EK F F KTL RK G EQEFI 376
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 395 RK I QS LG D SK T IPGD T A WL LYDTYGFP VDL T GLI A E E K G LV VD MD GF E E ER K LA Q LK S Q g KGA ggedlimldiyaieelr 474
Cdd:PRK01584 377 KL I PN LG S SK I IPGD I A FK LYDTYGFP YEI T EEL A S E Y G FT VD RE GF D E HF K KH Q KV S K - KGA ----------------- 438
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 475 arglevtddspkynyhldssgsyvfentvatvmalrr E K M F veevstgqecgvvldktcfyae Q GG qiydegylvk VD D S 554
Cdd:PRK01584 439 ------------------------------------- D K V F ---------------------- K GG ---------- LA D H 449
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 555 S EDK T EF tvknaqvrggyvlhigtiygdlkvgdqvwlfideprrrpimsn HTATH I L NF ALR S VLG E - AD QKGS LVAPD R 633
Cdd:PRK01584 450 S YET T KL ------------------------------------------- HTATH L L HK ALR L VLG D h VR QKGS NITAE R 486
650 660
....*....|....*....|....*....
gi 2217304800 634 LRFDF TAKGA M STQQ IKK A E E I A N EM I EA 662
Cdd:PRK01584 487 LRFDF SHPEK M TDDE IKK V E D I V N LQ I KN 515
AlaX
COG2872 Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ...
489-663
3.69e-21
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain]
Cd Length: 238
Bit Score: 92.95
E-value: 3.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 489 Y HL DS sgs Y VF E NT v ATV malrrekmfvee VSTGQ E C GVVLD K T C FY AEQ GGQ IY D E G Y LV K vddsse D KT E FT V KNAQV 568
Cdd:COG2872 6 Y LE DS --- Y LK E FE - ATV ------------ TAVTE E G GVVLD R T A FY PTG GGQ PG D T G T LV W ------ D GK E IR V VDVRK 63
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 569 RG G YVL H IGTIYGDLK VGD Q V WLF ID EP RR RPI M SN HTA T H I L NFALRSVL G e A DQK G SLVAP DR L R F DF t AKGAMSTQQ 648
Cdd:COG2872 64 ED G EIV H VLEGAPLPE VGD E V TGE ID WE RR YRH M RL HTA L H L L SAVVYREY G - A PVT G GQIGE DR A R I DF - DLPEFDEED 141
170
....*....|....*
gi 2217304800 649 IKKA E EI ANE M I E A A 663
Cdd:COG2872 142 LEEI E AE ANE L I A A D 156
PLN02961
PLN02961 alanine-tRNA ligase
525-618
8.31e-09
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain]
Cd Length: 223
Bit Score: 56.63
E-value: 8.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 525 CGV VLD K T C F YAEQ GGQ IY D E G YL V kvdd S S EDK T E F T V KNAQVRG G Y V L H I G TIY G ------- DLKV GD Q V WLFI DE P R 597
Cdd:PLN02961 3 IAL VLD R T I F HPQG GGQ PS D T G RI V ---- I S GGD T K F S V QDVRRKD G V V Y H Y G VFE G snpesas PFEA GD E V TVTV DE S R 78
90 100
....*....|....*....|.
gi 2217304800 598 R RPIMSN H T A T H I L NFALRS V 618
Cdd:PLN02961 79 R KLHSRL H S A G H L L DVCMAR V 99
mtIF2_IVc
cd03692 C2 subdomain of domain IV in mitochondrial translation initiation factor 2; This model ...
495-531
3.14e-04
C2 subdomain of domain IV in mitochondrial translation initiation factor 2; This model represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor EF-Tu. The C-terminal part of mtIF2 contains the entire fMet-tRNAfmet binding site of IF-2 and is resistant to proteolysis. This C-terminal portion consists of two domains, IF2 C1 and IF2 C2. IF2 C2 has been shown to contain all molecular determinants necessary and sufficient for the recognition and binding of fMet-tRNAfMet. Like IF2 from certain prokaryotes such as Thermus thermophilus, mtIF2lacks domain II which is thought to be involved in binding of E.coli IF-2 to 30S subunits.
Pssm-ID: 293893 [Multi-domain]
Cd Length: 84
Bit Score: 40.17
E-value: 3.14e-04
10 20 30
....*....|....*....|....*....|....*..
gi 2217304800 495 G SYVF E NTVAT vma L R R E K MF V E EV ST G Q ECG VV L DK 531
Cdd:cd03692 39 G EVIY E GKISS --- L K R F K DD V K EV KK G Y ECG IT L EN 72
class_II_aaRS-like_core
cd00768 Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA ...
8-247
8.80e-04
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. These enzymes are usually homodimers. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. The substrate specificity of this reaction is further determined by additional domains. Intererestingly, this domain is also found is asparagine synthase A (AsnA), in the accessory subunit of mitochondrial polymerase gamma and in the bacterial ATP phosphoribosyltransferase regulatory subunit HisZ.
Pssm-ID: 238391 [Multi-domain]
Cd Length: 211
Bit Score: 41.33
E-value: 8.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 8 S E I R Q RFID F FKR ---- NEH T YV ------- HSSATI P L D DPTLLFA N AGMNQFK P IF --- L NTIDP SH PMAKLS R A A NTQ 73
Cdd:cd00768 3 S K I E Q KLRR F MAE lgfq EVE T PI verepll EKAGHE P K D LLPVGAE N EEDLYLR P TL epg L VRLFV SH IRKLPL R L A EIG 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 74 KCI R AG G KHND L D dvgkdvy HHTF F EM L GSWS FG DYFK E LA ---- CKMAL E L L TQEF GI PIERLY V TYFG G DEAA glead 149
Cdd:cd00768 83 PAF R NE G GRRG L R ------- RVRE F TQ L EGEV FG EDGE E AS efee LIELT E E L LRAL GI KLDIVF V EKTP G EFSP ----- 150
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217304800 150 leckqiwqnlglddtkilpgnmkdnfwemgdt G PC GP CS EI HY D RIG GR D aahlvnqddpnv LEI WNLVFI Q YN ------ 223
Cdd:cd00768 151 -------------------------------- G GA GP GF EI EV D HPE GR G ------------ LEI GSGGYR Q DE qaraad 186
250 260
....*....|....*....|....*..
gi 2217304800 224 --- READGILKPL P KKSI dt G M GLERL 247
Cdd:cd00768 187 lyf LDEALEYRYP P TIGF -- G L GLERL 211
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
