pre-mRNA-processing factor 40 homolog B isoform X3 [Homo sapiens]
pre-mRNA-processing factor 40 family protein( domain architecture ID 13418230)
pre-mRNA-processing factor 40 (PRPF40) family protein similar to mammalian PRPF40 homologs A and B that may be involved in pre-mRNA splicing; contains WW and FF domains
List of domain hits
Name | Accession | Description | Interval | E-value | ||||||||
PRP40 super family | cl34905 | Splicing factor [RNA processing and modification]; |
119-611 | 8.28e-46 | ||||||||
Splicing factor [RNA processing and modification]; The actual alignment was detected with superfamily member COG5104: Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 174.11 E-value: 8.28e-46
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
663-711 | 1.17e-05 | ||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. : Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 43.33 E-value: 1.17e-05
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Name | Accession | Description | Interval | E-value | ||||||||
PRP40 | COG5104 | Splicing factor [RNA processing and modification]; |
119-611 | 8.28e-46 | ||||||||
Splicing factor [RNA processing and modification]; Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 174.11 E-value: 8.28e-46
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FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
308-357 | 2.19e-14 | ||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 67.87 E-value: 2.19e-14
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WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
167-196 | 6.72e-09 | ||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 51.76 E-value: 6.72e-09
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
307-360 | 1.59e-08 | ||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 51.42 E-value: 1.59e-08
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
663-711 | 1.17e-05 | ||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 43.33 E-value: 1.17e-05
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Name | Accession | Description | Interval | E-value | ||||||||
PRP40 | COG5104 | Splicing factor [RNA processing and modification]; |
119-611 | 8.28e-46 | ||||||||
Splicing factor [RNA processing and modification]; Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 174.11 E-value: 8.28e-46
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FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
308-357 | 2.19e-14 | ||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 67.87 E-value: 2.19e-14
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WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
167-196 | 6.72e-09 | ||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 51.76 E-value: 6.72e-09
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WW | pfam00397 | WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ... |
128-153 | 1.53e-08 | ||||||||
WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro. Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 50.97 E-value: 1.53e-08
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
307-360 | 1.59e-08 | ||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 51.42 E-value: 1.59e-08
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WW | smart00456 | Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ... |
168-196 | 4.24e-08 | ||||||||
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides. Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 49.52 E-value: 4.24e-08
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WW | pfam00397 | WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ... |
168-194 | 5.95e-08 | ||||||||
WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro. Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 49.04 E-value: 5.95e-08
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WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
128-153 | 1.09e-07 | ||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 48.68 E-value: 1.09e-07
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WW | smart00456 | Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ... |
128-153 | 2.75e-07 | ||||||||
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides. Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 47.60 E-value: 2.75e-07
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FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
522-577 | 8.87e-07 | ||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 46.30 E-value: 8.87e-07
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
663-711 | 1.17e-05 | ||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 43.33 E-value: 1.17e-05
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Blast search parameters | ||||
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