NCBI Conserved Domain Search

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

503-1021

1.16e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 86.14 E-value: 1.16e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  503 EWKEAEELGEDSAASLSLQLSLQRRStepvappEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLcqEEEE 582
Cdd:COG1196    217 ELKEELKELEAELLLLKLRELEAELE-------ELEAELEELEAELEELEAELAELEAELEELRLELEELELEL--EEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  583 EILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAER 662
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  663 ASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSS 742
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  743 LQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVM--------- 813
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrglagava 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  814 -------------------------------AKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLE 862
Cdd:COG1196    528 vligveaayeaaleaalaaalqnivveddevAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  863 DLRRRHREQERKLQDLELDLETRAKDVKARLA------LLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQK 936
Cdd:COG1196    608 LREADARYYVLGDTLLGRTLVAARLEAALRRAvtlagrLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  937 EHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKhfsSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIED 1016
Cdd:COG1196    688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ---LEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764


                   ....*
gi 2217281769 1017 LRKSL 1021
Cdd:COG1196    765 LEREL 769

PTZ00121

MAEBL; Provisional

503-996

5.50e-15

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 80.96 E-value: 5.50e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  503 EWKEAEELGEDSAASLSLQLSLQRRSTEPVAPPEqlseaALKAMEEAVAQVLEQDQRhllESKQEKMQQLREKLCQEEEE 582
Cdd:PTZ00121  1313 EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAE-----AAKAEAEAAADEAEAAEE---KAEAAEKKKEEAKKKADAAK 1384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  583 EILRLHQQKEQSLSSLRERLQKAieeEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAER 662
Cdd:PTZ00121  1385 KKAEEKKKADEAKKKAEEDKKKA---DELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEE 1461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  663 ASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVss 742
Cdd:PTZ00121  1462 AKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA-- 1539

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  743 lqKKIQEAQQKEEAQLQKCLGQVEHRvhQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEA 822
Cdd:PTZ00121  1540 --KKAEEKKKADELKKAEELKKAEEK--KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA 1615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  823 EERKQRAELLGHLTGELERLQRAHERELETVRQ-EQHKRLEDLRRRHREQERKlqdleldletRAKDVKARLALLEVQEE 901
Cdd:PTZ00121  1616 EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKaEELKKAEEENKIKAAEEAK----------KAEEDKKKAEEAKKAEE 1685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  902 TARREKQQLLDvqrqvalKSEEAtathQQLEEAQKEHTHLLQSNQQLREildELQARKLKLEsQVDLLQAQSQQLQKHFS 981
Cdd:PTZ00121  1686 DEKKAAEALKK-------EAEEA----KKAEELKKKEAEEKKKAEELKK---AEEENKIKAE-EAKKEAEEDKKKAEEAK 1750

                          490
                   ....*....|....*
gi 2217281769  982 SLEAEAQKKQHLLRE 996
Cdd:PTZ00121  1751 KDEEEKKKIAHLKKE 1765

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

556-1151

3.70e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 77.79 E-value: 3.70e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  556 QDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQAD 635
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEK-LEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  636 E-DQIRaEQEASLQKLREELESQQKAERASLEqKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEgeRKEAV 714
Cdd:TIGR02168  387 KvAQLE-LQIASLNNEIERLEARLERLEDRRE-RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE--RLEEA 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  715 ATLEKEHSAELERLCSSLEAKHREVVSslQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV----------AGYEHELS 784
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQA--RLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvdEGYEAAIE 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  785 SLLREKRQEVEGEHE----------------------------------RRLDKMKEEHQQVMAKAREQYEAEERKQRAE 830
Cdd:TIGR02168  541 AALGGRLQAVVVENLnaakkaiaflkqnelgrvtflpldsikgteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKALSY 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  831 LLGH------LTGELERLQRAHEREL----------------------ETVRQEQHKRLEDLRRRHREQERKLQDLEL-- 880
Cdd:TIGR02168  621 LLGGvlvvddLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKal 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  881 -DLETRAKDVKARLALLEVQEETARRE----KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDEL 955
Cdd:TIGR02168  701 aELRKELEELEEELEQLRKELEELSRQisalRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  956 QARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQK-KQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLS 1034
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAELTLlNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1035 QSKEDLYLDSLSSHNVWHL-----LSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVakdppgIKAL 1109
Cdd:TIGR02168  861 IEELEELIEELESELEALLnerasLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR------LEGL 934

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 2217281769 1110 EDMRKNL-----EKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSL 1151
Cdd:TIGR02168  935 EVRIDNLqerlsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

642-959

5.52e-14

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 77.09 E-value: 5.52e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  642 EQEASLQKLREELESQQKAERASLEQKNRQMLE-----QLKEEIEASEKSEQAALNAAKEKALQQLREQ-----LEGERK 711
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEaekarQAEMDRQAAIYAEQERMAMERERELERIRQEerkreLERIRQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  712 EAVAtLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQlqkclgqveHRVHQKSYHVAGYEHELSSLLREKR 791
Cdd:pfam17380  368 EEIA-MEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQ---------RKIQQQKVEMEQIRAEQEEARQREV 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  792 QEVEGEHERRLDKMKEEH---QQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQHKRLEDLRRRH 868
Cdd:pfam17380  438 RRLEEERAREMERVRLEEqerQQQVERLRQQEEERKRKKL---------ELEKEKRDRKRAEEQRRKILEKELEERKQAM 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  869 REQERKLQDLELDLETRAKDVKARLALLEVQEEtarREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHthllqsnQQL 948
Cdd:pfam17380  509 IEEERKRKLLEKEMEERQKAIYEEERRREAEEE---RRKQQEMEERRRIQEQMRKATEERSRLEAMERER-------EMM 578

                          330
                   ....*....|.
gi 2217281769  949 REILDELQARK 959
Cdd:pfam17380  579 RQIVESEKARA 589

cd00201

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ...

59-89

4.90e-06

Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 44.44 E-value: 4.90e-06

                           10        20        30
                   ....*....|....*....|....*....|.
gi 2217281769   59 PGEWKPCQDITGDIYYFNFANGQSMWDHPCD 89
Cdd:cd00201      1 PPGWEERWDPDGRVYYYNHNTKETQWEDPRE 31

pfam00397

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ...

58-87

1.21e-05

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro.

Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 43.26 E-value: 1.21e-05

                           10        20        30
                   ....*....|....*....|....*....|
gi 2217281769   58 LPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:pfam00397    1 LPPGWEERWDPDGRVYYYNHETGETQWEKP 30

smart00456

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...

57-87

2.99e-05

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.

Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 42.20 E-value: 2.99e-05

                            10        20        30
                    ....*....|....*....|....*....|.
gi 2217281769    57 PLPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:smart00456    1 PLPPGWEERKDPDGRPYYYNHETKETQWEKP 31

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

637-830

5.04e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 48.29 E-value: 5.04e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  637 DQIRAEQEASLQ--KLREELESQQKAERASLEQK----NRQMLEQLKEEIEASEKSEQAALNAAKEKAL----QQLREQL 706
Cdd:NF012221  1532 DNVVATSESSQQadAVSKHAKQDDAAQNALADKEraeaDRQRLEQEKQQQLAAISGSQSQLESTDQNALetngQAQRDAI 1611

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  707 EGERKEAVATLEK------------EHSAEL---------ERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgQV 765
Cdd:NF012221  1612 LEESRAVTKELTTlaqgldaldsqaTYAGESgdqwrnpfaGGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQ----KV 1687

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217281769  766 EHRVHQKSYHVA-GYEHELSSLLREKRQEVEGEhERRLDKMKEEHQQVMAKAREQYEAEERKQRAE 830
Cdd:NF012221  1688 KDAVAKSEAGVAqGEQNQANAEQDIDDAKADAE-KRKDDALAKQNEAQQAESDANAAANDAQSRGE 1752

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

743-914

8.85e-04

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 42.95 E-value: 8.85e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  743 LQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAG----YEHELSSLLRE-------------------KRQEVEGEHE 799
Cdd:cd16269    107 CKQNEEASSKRCQALLQELSAPLEEKISQGSYSVPGgyqlYLEDREKLVEKyrqvprkgvkaeevlqeflQSKEAEAEAI 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  800 RRLDKMKEEHQQVMAKAREQYEAEErkQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLE 879
Cdd:cd16269    187 LQADQALTEKEKEIEAERAKAEAAE--QERKLLEEQQRELEQKLEDQERSYEEHLRQLKEKMEEERENLLKEQERALESK 264

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2217281769  880 LDLETRakdvkarlALLEVQEETARREKQQLLDVQ 914
Cdd:cd16269    265 LKEQEA--------LLEEGFKEQAELLQEEIRSLK 291

OmpH

smart00935

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

648-753

3.21e-03

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 39.49 E-value: 3.21e-03

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769   648 QKLREELESQQKAERASLEQKNRQmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKehsaeler 727
Cdd:smart00935   17 KAAQKQLEKEFKKRQAELEKLEKE-LQKLKEKLQKDAATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQK-------- 87

                            90       100
                    ....*....|....*....|....*.
gi 2217281769   728 lcssleaKHREVVSSLQKKIQEAQQK 753
Cdd:smart00935   88 -------RQQEELQKILDKINKAIKE 106

Name

Accession

Description

Interval

E-value

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

503-1021

1.16e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 86.14 E-value: 1.16e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  503 EWKEAEELGEDSAASLSLQLSLQRRStepvappEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLcqEEEE 582
Cdd:COG1196    217 ELKEELKELEAELLLLKLRELEAELE-------ELEAELEELEAELEELEAELAELEAELEELRLELEELELEL--EEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  583 EILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAER 662
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  663 ASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSS 742
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  743 LQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVM--------- 813
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrglagava 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  814 -------------------------------AKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLE 862
Cdd:COG1196    528 vligveaayeaaleaalaaalqnivveddevAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  863 DLRRRHREQERKLQDLELDLETRAKDVKARLA------LLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQK 936
Cdd:COG1196    608 LREADARYYVLGDTLLGRTLVAARLEAALRRAvtlagrLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  937 EHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKhfsSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIED 1016
Cdd:COG1196    688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ---LEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764


                   ....*
gi 2217281769 1017 LRKSL 1021
Cdd:COG1196    765 LEREL 769

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

505-967

3.41e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.60 E-value: 3.41e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  505 KEAEELGEDSAASLSLQLSLQRRSTEpvappEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEI 584
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEE-----LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  585 LRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQ-SSTQADEDQIRAEQEASLQKLREELESQQKAERA 663
Cdd:COG1196    402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEaAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  664 SLEQKNRqmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSL 743
Cdd:COG1196    482 LLEELAE--AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVA 559

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  744 QKKIQEAQQKEEAQLQKC-LGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEhqqVMAKAREQYEA 822
Cdd:COG1196    560 AAAIEYLKAAKAGRATFLpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR---TLVAARLEAAL 636

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  823 EERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRhREQERKLQDLELDLETRAKDVKARLALLEVQEET 902
Cdd:COG1196    637 RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL-EELAERLAEEELELEEALLAEEEEERELAEAEEE 715

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217281769  903 ARREKQQLLDVQRQVALKSEEAtatHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVD 967
Cdd:COG1196    716 RLEEELEEEALEEQLEAEREEL---LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

540-1119

3.62e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.22 E-value: 3.62e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  540 EAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQ 619
Cdd:COG1196    228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  620 RLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLE--QKNRQMLEQLKEEIEASEKSEQAALNAAKEK 697
Cdd:COG1196    308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEeaEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  698 ALQQLREQLEGERKEA-VATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV 776
Cdd:COG1196    388 LLEALRAAAELAAQLEeLEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  777 AGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLtGELERLQRAHERELETVRQE 856
Cdd:COG1196    468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV-AVLIGVEAAYEAALEAALAA 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  857 QhkrledLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEAtathqqLEEAQK 936
Cdd:COG1196    547 A------LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL------READAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  937 EHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENnasphfepdlhIED 1016
Cdd:COG1196    615 YYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE-----------LEE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1017 LRKSLGTNQTKEVSSSLSQSKEDLyldslsshnvwHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASA 1096
Cdd:COG1196    684 LAERLAEEELELEEALLAEEEEER-----------ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                          570       580
                   ....*....|....*....|...
gi 2217281769 1097 QEVAKDPPGIKALEDMRKNLEKE 1119
Cdd:COG1196    753 LEELPEPPDLEELERELERLERE 775

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

621-1155

4.26e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.22 E-value: 4.26e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  621 LSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAAlnaaKEKALQ 700
Cdd:COG1196    232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE----QDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  701 QLREQLEGERKEAvatLEKEHSAELERLcssleAKHREVVSSLQKKIQEAQQKEEAQLQKclgqvehrvhqksyhVAGYE 780
Cdd:COG1196    308 EERRRELEERLEE---LEEELAELEEEL-----EELEEELEELEEELEEAEEELEEAEAE---------------LAEAE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  781 HELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKR 860
Cdd:COG1196    365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  861 LEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDvqrqvalksEEATATHQQLEEAQKEhTH 940
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL---------LEAEADYEGFLEGVKA-AL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  941 LLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQ----KKQHLLREVTVEENNASPHFEPDLHIED 1016
Cdd:COG1196    515 LLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAieylKAAKAGRATFLPLDKIRARAALAAALAR 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1017 LRKSLGTNQTKEvssslsqskEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASA 1096
Cdd:COG1196    595 GAIGAAVDLVAS---------DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217281769 1097 QEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEA 1155
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

565-1126

6.68e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.45 E-value: 6.68e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  565 KQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQE 644
Cdd:COG1196    211 KAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  645 ASLQKLREELESQQKAERASLEQKNRQmLEQLKEEIEASEK-----SEQAALNAAKEKALQQLREQLEGERKEAVATLEK 719
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEER-LEELEEELAELEEeleelEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  720 EHSAELERLcSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkcLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHE 799
Cdd:COG1196    370 AEAELAEAE-EELEELAEELLEALRAAAELAAQLEELEEA--EEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  800 RRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQ--- 876
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgav 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  877 DLELDLETRAKDV---KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILD 953
Cdd:COG1196    527 AVLIGVEAAYEAAleaALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  954 ELQARKLKLESQVDLLQAQSQQLQKHfSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIE-DLRKSLGTNQTKEVSSS 1032
Cdd:COG1196    607 DLREADARYYVLGDTLLGRTLVAARL-EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRrELLAALLEAEAELEELA 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1033 LSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDM 1112
Cdd:COG1196    686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765

                          570
                   ....*....|....
gi 2217281769 1113 RKNLEKETRHLDEM 1126
Cdd:COG1196    766 ERELERLEREIEAL 779

PTZ00121

MAEBL; Provisional

503-996

5.50e-15

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 80.96 E-value: 5.50e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  503 EWKEAEELGEDSAASLSLQLSLQRRSTEPVAPPEqlseaALKAMEEAVAQVLEQDQRhllESKQEKMQQLREKLCQEEEE 582
Cdd:PTZ00121  1313 EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAE-----AAKAEAEAAADEAEAAEE---KAEAAEKKKEEAKKKADAAK 1384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  583 EILRLHQQKEQSLSSLRERLQKAieeEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAER 662
Cdd:PTZ00121  1385 KKAEEKKKADEAKKKAEEDKKKA---DELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEE 1461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  663 ASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVss 742
Cdd:PTZ00121  1462 AKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA-- 1539

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  743 lqKKIQEAQQKEEAQLQKCLGQVEHRvhQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEA 822
Cdd:PTZ00121  1540 --KKAEEKKKADELKKAEELKKAEEK--KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA 1615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  823 EERKQRAELLGHLTGELERLQRAHERELETVRQ-EQHKRLEDLRRRHREQERKlqdleldletRAKDVKARLALLEVQEE 901
Cdd:PTZ00121  1616 EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKaEELKKAEEENKIKAAEEAK----------KAEEDKKKAEEAKKAEE 1685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  902 TARREKQQLLDvqrqvalKSEEAtathQQLEEAQKEHTHLLQSNQQLREildELQARKLKLEsQVDLLQAQSQQLQKHFS 981
Cdd:PTZ00121  1686 DEKKAAEALKK-------EAEEA----KKAEELKKKEAEEKKKAEELKK---AEEENKIKAE-EAKKEAEEDKKKAEEAK 1750

                          490
                   ....*....|....*
gi 2217281769  982 SLEAEAQKKQHLLRE 996
Cdd:PTZ00121  1751 KDEEEKKKIAHLKKE 1765

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

556-1151

3.70e-14

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 77.79 E-value: 3.70e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  556 QDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQAD 635
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEK-LEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  636 E-DQIRaEQEASLQKLREELESQQKAERASLEqKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEgeRKEAV 714
Cdd:TIGR02168  387 KvAQLE-LQIASLNNEIERLEARLERLEDRRE-RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE--RLEEA 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  715 ATLEKEHSAELERLCSSLEAKHREVVSslQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV----------AGYEHELS 784
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQA--RLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvdEGYEAAIE 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  785 SLLREKRQEVEGEHE----------------------------------RRLDKMKEEHQQVMAKAREQYEAEERKQRAE 830
Cdd:TIGR02168  541 AALGGRLQAVVVENLnaakkaiaflkqnelgrvtflpldsikgteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKALSY 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  831 LLGH------LTGELERLQRAHEREL----------------------ETVRQEQHKRLEDLRRRHREQERKLQDLEL-- 880
Cdd:TIGR02168  621 LLGGvlvvddLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKal 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  881 -DLETRAKDVKARLALLEVQEETARRE----KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDEL 955
Cdd:TIGR02168  701 aELRKELEELEEELEQLRKELEELSRQisalRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  956 QARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQK-KQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLS 1034
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAELTLlNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1035 QSKEDLYLDSLSSHNVWHL-----LSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVakdppgIKAL 1109
Cdd:TIGR02168  861 IEELEELIEELESELEALLnerasLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR------LEGL 934

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 2217281769 1110 EDMRKNL-----EKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSL 1151
Cdd:TIGR02168  935 EVRIDNLqerlsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

642-959

5.52e-14

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 77.09 E-value: 5.52e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  642 EQEASLQKLREELESQQKAERASLEQKNRQMLE-----QLKEEIEASEKSEQAALNAAKEKALQQLREQ-----LEGERK 711
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEaekarQAEMDRQAAIYAEQERMAMERERELERIRQEerkreLERIRQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  712 EAVAtLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQlqkclgqveHRVHQKSYHVAGYEHELSSLLREKR 791
Cdd:pfam17380  368 EEIA-MEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQ---------RKIQQQKVEMEQIRAEQEEARQREV 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  792 QEVEGEHERRLDKMKEEH---QQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQHKRLEDLRRRH 868
Cdd:pfam17380  438 RRLEEERAREMERVRLEEqerQQQVERLRQQEEERKRKKL---------ELEKEKRDRKRAEEQRRKILEKELEERKQAM 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  869 REQERKLQDLELDLETRAKDVKARLALLEVQEEtarREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHthllqsnQQL 948
Cdd:pfam17380  509 IEEERKRKLLEKEMEERQKAIYEEERRREAEEE---RRKQQEMEERRRIQEQMRKATEERSRLEAMERER-------EMM 578

                          330
                   ....*....|.
gi 2217281769  949 REILDELQARK 959
Cdd:pfam17380  579 RQIVESEKARA 589

PTZ00121

MAEBL; Provisional

453-1154

7.90e-14

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.10 E-value: 7.90e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  453 QSSQDELQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEPPQGPEGQP-----EWKEAEELGEDSAASLSLQLSLQRR 527
Cdd:PTZ00121  1086 DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKaedarKAEEARKAEDAKRVEIARKAEDARK 1165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  528 STEP-VAPPEQLSEAALKAMEEAVAQVL---------EQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSS 597
Cdd:PTZ00121  1166 AEEArKAEDAKKAEAARKAEEVRKAEELrkaedarkaEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKA 1245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  598 LRERLQKAIEEEEARMREEESQRLSWLRAQvqSSTQADEDQiRAEQEASLQKLREElESQQKAERASLEQKNRQMLEQLK 677
Cdd:PTZ00121  1246 EEERNNEEIRKFEEARMAHFARRQAAIKAE--EARKADELK-KAEEKKKADEAKKA-EEKKKADEAKKKAEEAKKADEAK 1321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  678 EEIEASEKSEQAALNAAKE--KALQQLREQLEGERKEAVATLEKEHSAELERLcsslEAKHRevVSSLQKKIQEAQQKEE 755
Cdd:PTZ00121  1322 KKAEEAKKKADAAKKKAEEakKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE----EAKKK--ADAAKKKAEEKKKADE 1395

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  756 AQlqkclgqvehrvhQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQvmaKAREQYEAEERKQRAELLGHL 835
Cdd:PTZ00121  1396 AK-------------KKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK---KAEEAKKADEAKKKAEEAKKA 1459

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  836 TGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLAllevqeETARREKQqlldvqr 915
Cdd:PTZ00121  1460 EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA------EEAKKADE------- 1526

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  916 qvALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQvdllqaqsqqlQKHFSSLEAEAQKKqhlLR 995
Cdd:PTZ00121  1527 --AKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEE-----------DKNMALRKAEEAKK---AE 1590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  996 EVTVEENNASPHFEPDLHIEDLRKSlgtNQTKEVSSSLSQSKEDlyldslsSHNVWHLLSAEGVALRSAKEFL-VQQTRS 1074
Cdd:PTZ00121  1591 EARIEEVMKLYEEEKKMKAEEAKKA---EEAKIKAEELKKAEEE-------KKKVEQLKKKEAEEKKKAEELKkAEEENK 1660

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1075 MRRRQTALKAAQQHWRHELA---------SAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA----MRKGHNLLKKKE 1141
Cdd:PTZ00121  1661 IKAAEEAKKAEEDKKKAEEAkkaeedekkAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAeeenKIKAEEAKKEAE 1740

                          730
                   ....*....|...
gi 2217281769 1142 EKLNQLESSLWEE 1154
Cdd:PTZ00121  1741 EDKKKAEEAKKDE 1753

PRK02224

DNA double-strand break repair Rad50 ATPase;

541-966

9.16e-13

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 73.15 E-value: 9.16e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  541 AALKAMEEAVAQVLEQDQRhlLESKQEKMQQLREKLcqeeeEEILRLHQQKEQSLSSLRERLQK--AIEEEEARMREEES 618
Cdd:PRK02224   206 ERLNGLESELAELDEEIER--YEEQREQARETRDEA-----DEVLEEHEERREELETLEAEIEDlrETIAETEREREELA 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  619 QRLSWLRAQVQ------SSTQADEDQIRAEQEASLQKlREELESQQKAERASLEQKnRQMLEQLKEEIE----------- 681
Cdd:PRK02224   279 EEVRDLRERLEeleeerDDLLAEAGLDDADAEAVEAR-REELEDRDEELRDRLEEC-RVAAQAHNEEAEslredaddlee 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  682 -ASEKSEQAAlnaAKEKALQQLREQLEgERKEAVATLEKE-----------------HSAELERLCSSLEAKHREV---- 739
Cdd:PRK02224   357 rAEELREEAA---ELESELEEAREAVE-DRREEIEELEEEieelrerfgdapvdlgnAEDFLEELREERDELREREaele 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  740 --VSSLQKKIQEAQQ-KEEAQLQKCLGQVEHRVH-----QKSYHVAGYEHELSSLlREKRQEVEGEHER---------RL 802
Cdd:PRK02224   433 atLRTARERVEEAEAlLEAGKCPECGQPVEGSPHvetieEDRERVEELEAELEDL-EEEVEEVEERLERaedlveaedRI 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  803 DKMKEEHQQVMAKAREQYE-AEERKQRAELLGHLTGELErlqrAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELD 881
Cdd:PRK02224   512 ERLEERREDLEELIAERREtIEEKRERAEELRERAAELE----AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKER 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  882 LEtRAKDVKARLALLEVQEETA-----RREKQQLLDVQRQVALKSE-------EATATHQQLEEAQKEHTHLLQSNQQLR 949
Cdd:PRK02224   588 IE-SLERIRTLLAAIADAEDEIerlreKREALAELNDERRERLAEKrerkrelEAEFDEARIEEAREDKERAEEYLEQVE 666

                          490
                   ....*....|....*..
gi 2217281769  950 EILDELQARKLKLESQV 966
Cdd:PRK02224   667 EKLDELREERDDLQAEI 683

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

647-965

1.51e-12

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.78 E-value: 1.51e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  647 LQKLREELESQQKaeraSLEQKNRQMlEQLKEeIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVaTLEKEHSAELE 726
Cdd:TIGR02168  191 LEDILNELERQLK----SLERQAEKA-ERYKE-LKAELRELELALLVLRLEELREELEELQEELKEAE-EELEELTAELQ 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  727 RLCSSLEAkHREVVSSLQKKIQEAQQKEEA---QLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVE-GEHERRL 802
Cdd:TIGR02168  264 ELEEKLEE-LRLEVSELEEEIEELQKELYAlanEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDElAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  803 DKMKEEHQQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQH---KRLEDLRRRHREQERKLQDLE 879
Cdd:TIGR02168  343 EEKLEELKEELESLEAELEELEAELE---------ELESRLEELEEQLETLRSKVAqleLQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  880 ldlETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATH-QQLEEAQKEHTHLLQSNQQLREILDELQAR 958
Cdd:TIGR02168  414 ---DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLeEALEELREELEEAEQALDAAERELAQLQAR 490


                   ....*..
gi 2217281769  959 KLKLESQ 965
Cdd:TIGR02168  491 LDSLERL 497

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

547-1155

2.17e-12

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 71.92 E-value: 2.17e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  547 EEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEilrlhQQKEQSLSSLRERLQKAieeeeaRMREEESQRLSWLRA 626
Cdd:TIGR00618  199 LTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREAL-----QQTQQSHAYLTQKREAQ------EEQLKKQQLLKQLRA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  627 QVQSSTQadedqiraeQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALnaakEKALQQLREQL 706
Cdd:TIGR00618  268 RIEELRA---------QEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSR----AKLLMKRAAHV 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  707 egerkeavatlekEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSL 786
Cdd:TIGR00618  335 -------------KQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  787 lrekrqevegeherrLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRR 866
Cdd:TIGR00618  402 ---------------LDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQ 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  867 RHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLL--DVQRQVALKSEEATATHQQLEEaqkEHTHLLQS 944
Cdd:TIGR00618  467 SLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIhpNPARQDIDNPGPLTRRMQRGEQ---TYAQLETS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  945 NQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREV---TVEENNASPHFEPDLHIEDLRKSL 1021
Cdd:TIGR00618  544 EEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLqdlTEKLSEAEDMLACEQHALLRKLQP 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1022 GTNQtKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGV--ALRSAKEFlvqQTRSMRRRQTALKAAQQ------HWRHEL 1093
Cdd:TIGR00618  624 EQDL-QDVRLHLQQCSQELALKLTALHALQLTLTQERVreHALSIRVL---PKELLASRQLALQKMQSekeqltYWKEML 699

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217281769 1094 ASAQEvakdppgikALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEA 1155
Cdd:TIGR00618  700 AQCQT---------LLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA 752

PTZ00121

MAEBL; Provisional

446-1154

1.15e-11

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 70.17 E-value: 1.15e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  446 IEDKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQSPPR--SLATEEEPPQGPEGQPEwkEAEELGEDSAASLSLQLS 523
Cdd:PTZ00121  1047 IIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNraDEATEEAFGKAEEAKKT--ETGKAEEARKAEEAKKKA 1124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  524 LQRRSTEPVAPPEQLSEAalkamEEAvaQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQ 603
Cdd:PTZ00121  1125 EDARKAEEARKAEDARKA-----EEA--RKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAE 1197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  604 KAIEEEEARMREEESQRLSWLRAqvqsstqadEDQIRAEQEASLQKLREELESQQKAEraslEQKNRQMLEQLKEEIEAS 683
Cdd:PTZ00121  1198 DARKAEAARKAEEERKAEEARKA---------EDAKKAEAVKKAEEAKKDAEEAKKAE----EERNNEEIRKFEEARMAH 1264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  684 EKSEQAALNAAKEKALQQLREQLEGER-KEAVATLEKEHSAELERlcsslEAKHREVVSSLQKKIQEAQQKEEAQLQKCl 762
Cdd:PTZ00121  1265 FARRQAAIKAEEARKADELKKAEEKKKaDEAKKAEEKKKADEAKK-----KAEEAKKADEAKKKAEEAKKKADAAKKKA- 1338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  763 gqvehRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERL 842
Cdd:PTZ00121  1339 -----EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKA 1413

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  843 QRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSE 922
Cdd:PTZ00121  1414 AAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE 1493

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  923 EATATHQQLEEAQKEHthllQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHfsslEAEAQKKQHLLREVTVEEN 1002
Cdd:PTZ00121  1494 EAKKKADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK----KADELKKAEELKKAEEKKK 1565

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1003 NASPHFEPDLHIEDLRKslgtnqtkevSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTAL 1082
Cdd:PTZ00121  1566 AEEAKKAEEDKNMALRK----------AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKV 1635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1083 KAAQQHWRHELASAQEVAK--DPPGIKALEDMRKNlEKETRHLDEMKSA---MRKGHNLLKKKEE---KLNQLESSLWEE 1154
Cdd:PTZ00121  1636 EQLKKKEAEEKKKAEELKKaeEENKIKAAEEAKKA-EEDKKKAEEAKKAeedEKKAAEALKKEAEeakKAEELKKKEAEE 1714

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

544-1040

1.28e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 69.56 E-value: 1.28e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  544 KAMEEAVAQVLEQDQRhlLESKQEKMQQLREKLcqeeeeEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW 623
Cdd:COG4913    221 PDTFEAADALVEHFDD--LERAHEALEDAREQI------ELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  624 LRAQVQSSTQADEDQirAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAK--EKALQQ 701
Cdd:COG4913    293 LEAELEELRAELARL--EAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRArlEALLAA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  702 LREQLEGERkEAVATLEKEHSAELERLcSSLEAKHREVVSSLQKKIQEAQqKEEAQLQKCLGQVEHRVHQKSYHVAGYEH 781
Cdd:COG4913    371 LGLPLPASA-EEFAALRAEAAALLEAL-EEELEALEEALAEAEAALRDLR-RELRELEAEIASLERRKSNIPARLLALRD 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  782 ELSSLLREKRQE---------------------------------VEGEHERR----LDKMKEEHQQVMAKAREQYEAEE 824
Cdd:COG4913    448 ALAEALGLDEAElpfvgelievrpeeerwrgaiervlggfaltllVPPEHYAAalrwVNRLHLRGRLVYERVRTGLPDPE 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  825 RKQRAEllGHLTGELE------------RLQR-------AHERELET----------VRQEQHKRLEDLRRRHREQ---- 871
Cdd:COG4913    528 RPRLDP--DSLAGKLDfkphpfrawleaELGRrfdyvcvDSPEELRRhpraitragqVKGNGTRHEKDDRRRIRSRyvlg 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  872 ---ERKLQDLELD---LETRAKDVKARLALLEVQEETARREKQQLLDVQrQVALKSEEATATHQQLEEAQKEHTHLLQSN 945
Cdd:COG4913    606 fdnRAKLAALEAElaeLEEELAEAEERLEALEAELDALQERREALQRLA-EYSWDEIDVASAEREIAELEAELERLDASS 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  946 ---QQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVtveENNASPHFEPDLhIEDLRKSLG 1022
Cdd:COG4913    685 ddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA---EDLARLELRALL-EERFAAALG 760

                          570
                   ....*....|....*...
gi 2217281769 1023 TNQTKEVSSSLSQSKEDL 1040
Cdd:COG4913    761 DAVERELRENLEERIDAL 778

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

547-958

3.12e-11

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.54 E-value: 3.12e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  547 EEAVAQVLEQDQRhlLESKQEKMQQLREKLcqeeeeeilRLHQQKEQSLSSLRERLQKAIEEEEARMREEeSQRLSWLRA 626
Cdd:TIGR02168  666 AKTNSSILERRRE--IEELEEKIEELEEKI---------AELEKALAELRKELEELEEELEQLRKELEEL-SRQISALRK 733

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  627 QVQSSTQadEDQIRAEQEASLQKLREELEsQQKAERASLEQKNRQMLEQLKEEIEasekSEQAALNAAKEkALQQLREQL 706
Cdd:TIGR02168  734 DLARLEA--EVEQLEERIAQLSKELTELE-AEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKE-ELKALREAL 805

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  707 EGERKEavATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEaqlqkclgqvehrvhqksyHVAGYEHELSSl 786
Cdd:TIGR02168  806 DELRAE--LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE-------------------DIESLAAEIEE- 863

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  787 LREKRQEVEGEHErRLDKMKEEHQQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQHK---RLED 863
Cdd:TIGR02168  864 LEELIEELESELE-ALLNERASLEEALALLRSELEELSEELR---------ELESKRSELRRELEELREKLAQlelRLEG 933

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  864 LR-RRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRqVALKS-EEATATHQQLEEAQKEHTHL 941
Cdd:TIGR02168  934 LEvRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP-VNLAAiEEYEELKERYDFLTAQKEDL 1012

                          410
                   ....*....|....*..
gi 2217281769  942 LQSNQQLREILDELQAR 958
Cdd:TIGR02168 1013 TEAKETLEEAIEEIDRE 1029

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

505-913

4.27e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 67.65 E-value: 4.27e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  505 KEAEELGEDSAASLSLQLSLQRRSTEpvappeQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLcQEEEEEI 584
Cdd:COG1196    421 EELEELEEALAELEEEEEEEEEALEE------AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL-AEAAARL 493

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  585 LRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW---LRAQVQSSTQADEDQIRAEQEASLQKLREELEsQQKAE 661
Cdd:COG1196    494 LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVeaaYEAALEAALAAALQNIVVEDDEVAAAAIEYLK-AAKAG 572

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  662 RASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERkEAVATLEKEHSAELERLCSSLEAKHREVvS 741
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREV-T 650

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  742 SLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSyhvagyehELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYE 821
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELE--------ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  822 AEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLE---LDLETRAKDVKARLALLEV 898
Cdd:COG1196    723 EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGpvnLLAIEEYEELEERYDFLSE 802

                          410
                   ....*....|....*
gi 2217281769  899 QEETARREKQQLLDV 913
Cdd:COG1196    803 QREDLEEARETLEEA 817

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

540-913

1.61e-10

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.23 E-value: 1.61e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  540 EAALKAMEEAVAQVleQDQRHLLESKQEKMQQLREKLcqeeeeeiLRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQ 619
Cdd:TIGR02168  683 EEKIEELEEKIAEL--EKALAELRKELEELEEELEQL--------RKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  620 RLSWLRAQVQSSTQADEdqiraEQEASLQKLREElesqqkAERASLEQKNRQMLEQLKEEIEASeKSEQAALNAAKEKAl 699
Cdd:TIGR02168  753 SKELTELEAEIEELEER-----LEEAEEELAEAE------AEIEELEAQIEQLKEELKALREAL-DELRAELTLLNEEA- 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  700 QQLREQLEGERKEAVATlekehSAELERLCSSLEAKhREVVSSLQKKIQEAQQKEEAQlqkclgQVEHRVHQKSYHVAGY 779
Cdd:TIGR02168  820 ANLRERLESLERRIAAT-----ERRLEDLEEQIEEL-SEDIESLAAEIEELEELIEEL------ESELEALLNERASLEE 887

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  780 EHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKareQYEAEERKQRAELLghLTGELERLQRAHERELETVRQEQHK 859
Cdd:TIGR02168  888 ALALLRSELEELSEELRELESKRSELRRELEELREK---LAQLELRLEGLEVR--IDNLQERLSEEYSLTLEEAEALENK 962

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  860 RLED---LRRRHREQERKLQDL---ELDLETRAKDVKARLALLEVQEETARREKQQLLDV 913
Cdd:TIGR02168  963 IEDDeeeARRRLKRLENKIKELgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

438-955

1.69e-10

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 65.76 E-value: 1.69e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  438 RQAQQPLGIEDKDDSQSSQDELQSKQSKGLEErlsppLPHEERAQSPPRSLATEEEPPQGPEGQpewKEAEELGEDSAAS 517
Cdd:TIGR00618  359 DAHEVATSIREISCQQHTLTQHIHTLQQQKTT-----LTQKLQSLCKELDILQREQATIDTRTS---AFRDLQGQLAHAK 430

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  518 LSLQLSLQRRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKlcQEEEEEILRLHQQKEQSL-S 596
Cdd:TIGR00618  431 KQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRK--KAVVLARLLELQEEPCPLcG 508

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  597 SLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEaSLQKLREELESQQKAERASLEQKNR--QMLE 674
Cdd:TIGR00618  509 SCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERK-QRASLKEQMQEIQQSFSILTQCDNRskEDIP 587

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  675 QLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEA---- 750
Cdd:TIGR00618  588 NLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHalsi 667

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  751 -QQKEE--AQLQKCLGQVEHRVHQKSYHVAGYEHELSsLLREkrqevEGEHERRLDKMKEEHQQVMAKAREQYEAEE--- 824
Cdd:TIGR00618  668 rVLPKEllASRQLALQKMQSEKEQLTYWKEMLAQCQT-LLRE-----LETHIEEYDREFNEIENASSSLGSDLAAREdal 741

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  825 -------RKQRAELLGHLTGELERLQRAHERELETVRQEQHKRlEDLRRRHREQERKLQDLELDLETRAKDVKARLALLE 897
Cdd:TIGR00618  742 nqslkelMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLA-AEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILN 820

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2217281769  898 VQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDEL 955
Cdd:TIGR00618  821 LQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

562-1150

1.93e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 65.91 E-value: 1.93e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  562 LESKQEKMQQLREKLCQeeeeeilrLHQQKEQSLSSLRERLQKAIEEEEARMReeesqrlswLRAQVQSSTQADEDQIRA 641
Cdd:pfam15921  115 LQTKLQEMQMERDAMAD--------IRRRESQSQEDLRNQLQNTVHELEAAKC---------LKEDMLEDSNTQIEQLRK 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  642 ---EQEASLQKLR------EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLrEQLEGERKE 712
Cdd:pfam15921  178 mmlSHEGVLQEIRsilvdfEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQL-EALKSESQN 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  713 AVATLEKEHSAELERLCSsleaKHREVVSSLQKKIQEAQQKEEAqLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQ 792
Cdd:pfam15921  257 KIELLLQQHQDRIEQLIS----EHEVEITGLTEKASSARSQANS-IQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRS 331

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  793 EVEGEHERRLDKMKEEHQQVMAKAREQYEAE-ERKQRAELLGHLTGELERL-QRAHERELE-TVRQEQHKRLEDlrrRHR 869
Cdd:pfam15921  332 ELREAKRMYEDKIEELEKQLVLANSELTEARtERDQFSQESGNLDDQLQKLlADLHKREKElSLEKEQNKRLWD---RDT 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  870 EQERKLQDLELDLETRAKDVKARLALLE-VQEETARREKQQLLDVQrqvalkseeatATHQQLEEAQKEHTHLLQSNQQL 948
Cdd:pfam15921  409 GNSITIDHLRRELDDRNMEVQRLEALLKaMKSECQGQMERQMAAIQ-----------GKNESLEKVSSLTAQLESTKEML 477

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  949 REILDELQARKLKLESQvdllqaqsqqlQKHFSSLEAEAQKKQHLLR----EVTVEENNASPHFEPDLHIEDLRKSLGTN 1024
Cdd:pfam15921  478 RKVVEELTAKKMTLESS-----------ERTVSDLTASLQEKERAIEatnaEITKLRSRVDLKLQELQHLKNEGDHLRNV 546

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1025 QTKEVSSSLSQSKEDLYLDSLSSH--NVWHLLSAEGvalRSAKEFLVQQTRsmrrrqtaLKAAQQHWRHELASAQEVA-K 1101
Cdd:pfam15921  547 QTECEALKLQMAEKDKVIEILRQQieNMTQLVGQHG---RTAGAMQVEKAQ--------LEKEINDRRLELQEFKILKdK 615

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1102 DPPGIKALEDMRKNLEKETRHLDEMKSA-MRKGHNLLKKKEEKLNQLESS 1150
Cdd:pfam15921  616 KDAKIRELEARVSDLELEKVKLVNAGSErLRAVKDIKQERDQLLNEVKTS 665

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

683-1021

3.44e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.09 E-value: 3.44e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  683 SEKSEQAALNAAKEKA-LQQLREQLEGERKEAVATLEKEHSAELER--LCSSLEAKHREVvSSLQKKIQEAQQKEEAQLQ 759
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAeLQRLRERLEGLKRELSSLQSELRRIENRLdeLSQELSDASRKI-GEIEKEIEQLEQEEEKLKE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  760 KcLGQVEHRVHQKSYHVAGYEHELSsllrekrqevegeherRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGEL 839
Cdd:TIGR02169  738 R-LEELEEDLSSLEQEIENVKSELK----------------ELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAEL 800

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  840 erlqraheRELETVRQEQHKRLEDLrrrhreqERKLQDLELDLEtrakdvkarLALLEVQEETARRE--KQQLLDVQRQV 917
Cdd:TIGR02169  801 --------SKLEEEVSRIEARLREI-------EQKLNRLTLEKE---------YLEKEIQELQEQRIdlKEQIKSIEKEI 856

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  918 ALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREV 997
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI 936

                          330       340
                   ....*....|....*....|....
gi 2217281769  998 TVEENNASPHFEPDLHIEDLRKSL 1021
Cdd:TIGR02169  937 EDPKGEDEEIPEEELSLEDVQAEL 960

PRK02224

DNA double-strand break repair Rad50 ATPase;

631-879

3.88e-10

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 64.68 E-value: 3.88e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  631 STQADEDQIRAEQEASLQKLREELES-QQKAERASLEQKNRQMLEQLKEEIEASEK--SEQAALNAAKEKALQQLREQLE 707
Cdd:PRK02224   468 ETIEEDRERVEELEAELEDLEEEVEEvEERLERAEDLVEAEDRIERLEERREDLEEliAERRETIEEKRERAEELRERAA 547

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  708 GERKEAVATLEKEHSAELErlcsslEAKHREVVSSLQKKIQEAQQKEEAqlqkcLGQVEHRVHQksyhVAGYEHELSSLl 787
Cdd:PRK02224   548 ELEAEAEEKREAAAEAEEE------AEEAREEVAELNSKLAELKERIES-----LERIRTLLAA----IADAEDEIERL- 611

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  788 REKR---QEVEGEHERRLDKMKEEHQQVMAKAREQY--EAEERKQRAE-LLGHLTGELERLqRAHERELET----VRQEQ 857
Cdd:PRK02224   612 REKRealAELNDERRERLAEKRERKRELEAEFDEARieEAREDKERAEeYLEQVEEKLDEL-REERDDLQAeigaVENEL 690

                          250       260
                   ....*....|....*....|..
gi 2217281769  858 hKRLEDLRRRHREQERKLQDLE 879
Cdd:PRK02224   691 -EELEELRERREALENRVEALE 711

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

796-1121

7.84e-10

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.92 E-value: 7.84e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  796 GEHERRLDKMKEEHQQVMaKAREQYEAEERKQRAELLGHLT---GELERLQRAHER------ELETVRQEQHKRLEDLRR 866
Cdd:TIGR02168  196 NELERQLKSLERQAEKAE-RYKELKAELRELELALLVLRLEelrEELEELQEELKEaeeeleELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  867 RHREQERKLQDLEldleTRAKDVKARLALLEVQEETARREKQQLldvQRQVALKSEEATATHQQLEEAQKEHThllqsnq 946
Cdd:TIGR02168  275 EVSELEEEIEELQ----KELYALANEISRLEQQKQILRERLANL---ERQLEELEAQLEELESKLDELAEELA------- 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  947 QLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEP-DLHIEDLRKSLgtNQ 1025
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERlEARLERLEDRR--ER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1026 TKEVSSSLSQSKEDLYLDSLSSHNVwhLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEvakdppG 1105
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAELE--ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA------R 490

                          330
                   ....*....|....*.
gi 2217281769 1106 IKALEDMRKNLEKETR 1121
Cdd:TIGR02168  491 LDSLERLQENLEGFSE 506

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

567-966

1.45e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 62.48 E-value: 1.45e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  567 EKMQQLREKLcqEEEEEILRLHQQKEQSLSSLRERLQKAieeeeARMREEESQRLSWLRAQVQsstQADEDQIRAEQEAS 646
Cdd:COG4717     71 KELKELEEEL--KEAEEKEEEYAELQEELEELEEELEEL-----EAELEELREELEKLEKLLQ---LLPLYQELEALEAE 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  647 LQKLREELES--QQKAERASLEQKNRQMLEQLkEEIEASEKSEQAALNAAKEKALQQLREQLEgERKEAVATLEKEhSAE 724
Cdd:COG4717    141 LAELPERLEEleERLEELRELEEELEELEAEL-AELQEELEELLEQLSLATEEELQDLAEELE-ELQQRLAELEEE-LEE 217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  725 LERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQV------EHRVHQKSYHVAGYEHELSSLLREKRQEVEGEH 798
Cdd:COG4717    218 AQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALlallglGGSLLSLILTIAGVLFLVLGLLALLFLLLAREK 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  799 ERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKlqdl 878
Cdd:COG4717    298 ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA---- 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  879 ELDLETRAKDVKARLALLE-VQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQA 957
Cdd:COG4717    374 ALLAEAGVEDEEELRAALEqAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELRE 453


                   ....*....
gi 2217281769  958 RKLKLESQV 966
Cdd:COG4717    454 ELAELEAEL 462

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

540-955

2.61e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 61.71 E-value: 2.61e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  540 EAALKAMEEAVAQVLE-QDQRHLLESKQEKMQQLREKLCQEEEE-EILRLHQQKEQSLSSLRERLQkaieeeearmreEE 617
Cdd:COG4717     77 EEELKEAEEKEEEYAElQEELEELEEELEELEAELEELREELEKlEKLLQLLPLYQELEALEAELA------------EL 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  618 SQRLSWLRAQVQSSTQADEDQIRAEQEasLQKLREELESQQKAERASLEQKNRQMLEQLkEEIEASEKSEQAALNAAKEK 697
Cdd:COG4717    145 PERLEELEERLEELRELEEELEELEAE--LAELQEELEELLEQLSLATEEELQDLAEEL-EELQQRLAELEEELEEAQEE 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  698 aLQQLREQLEGERKEAVATLEKEHSAELERL-------------------------------------CSSLEAKHREVV 740
Cdd:COG4717    222 -LEELEEELEQLENELEAAALEERLKEARLLlliaaallallglggsllsliltiagvlflvlgllalLFLLLAREKASL 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  741 SSLQKKIQEAQQK---EEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKA- 816
Cdd:COG4717    301 GKEAEELQALPALeelEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAg 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  817 ----------------REQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLEL 880
Cdd:COG4717    381 vedeeelraaleqaeeYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEA 460

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217281769  881 DLETRAKDvkARLALLEVQEETARREKQQLldVQRQVALKseeatATHQQLEEAQKEHTHLLQS--NQQLREILDEL 955
Cdd:COG4717    461 ELEQLEED--GELAELLQELEELKAELREL--AEEWAALK-----LALELLEEAREEYREERLPpvLERASEYFSRL 528

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

536-1158

4.04e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 61.53 E-value: 4.04e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  536 EQLSEAALKAMEEAVAQVLEQDQRHLLEsKQEKMQQLREKLCQ--EEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARM 613
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELK-LQELKLKEQAKKALeyYQLKEKLELEEEYLL-YLDYLKLNEERIDLLQELL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  614 REEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM------LEQLKEEIEASEKSE 687
Cdd:pfam02463  247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLerrkvdDEEKLKESEKEKKKA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  688 QAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkCLGQVEH 767
Cdd:pfam02463  327 EKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-LKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  768 RVHQKSYHVAGYEHELSSLLREKRQEVEGEhERRLDKMKEEHQQVMAKAREQYEAEERKQRAEllghltgELERLQRAHE 847
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEE-EESIELKQGKLTEEKEELEKQELKLLKDELEL-------KKSEDLLKET 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  848 RELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALkSEEATAT 927
Cdd:pfam02463  478 QLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV-IVEVSAT 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  928 HQQLEEAQKEHTHLLQSNQqlreILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPH 1007
Cdd:pfam02463  557 ADEVEERQKLVRALTELPL----GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDT 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1008 FEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSshnvwhLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQ 1087
Cdd:pfam02463  633 ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSEL------TKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217281769 1088 HWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEASDE 1158
Cdd:pfam02463  707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

584-912

8.43e-09

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 60.37 E-value: 8.43e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  584 ILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERA 663
Cdd:pfam02463  164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQ 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  664 SLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQlreQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSL 743
Cdd:pfam02463  244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEK---KLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  744 QKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYE-A 822
Cdd:pfam02463  321 KEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELElK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  823 EERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEET 902
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330
                   ....*....|
gi 2217281769  903 ARREKQQLLD 912
Cdd:pfam02463  481 KLQEQLELLL 490

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

523-912

9.01e-09

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.47 E-value: 9.01e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  523 SLQRRSTEPVAPPEQLSEAALKAMEEAVaqvleQDQRHLLESKQEKMQQLREKLCQEEeeeilrlhQQKEQSLSSLRERL 602
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGL-----KRELSSLQSELRRIENRLDELSQEL--------SDASRKIGEIEKEI 725

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  603 QKAieeeeARMREEESQRLSWLRAQVQSSTQADEDQIR---------AEQEASLQKLREELESQQKAERASLEQKNRQML 673
Cdd:TIGR02169  726 EQL-----EQEEEKLKERLEELEEDLSSLEQEIENVKSelkeleariEELEEDLHKLEEALNDLEARLSHSRIPEIQAEL 800

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  674 EQLKEEIeaSEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEkehsaelerlcssleakhrevvsSLQKKIQEAQQK 753
Cdd:TIGR02169  801 SKLEEEV--SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI-----------------------DLKEQIKSIEKE 855

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  754 EEAqLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRqevegEHERRLDKMKEEHQQvmAKAREQYEAEERKQRAELLG 833
Cdd:TIGR02169  856 IEN-LNGKKEELEEELEELEAALRDLESRLGDLKKERD-----ELEAQLRELERKIEE--LEAQIEKKRKRLSELKAKLE 927

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  834 HLTGELERLQRAHERELETVRQEQhkRLEDLRRRHREQERKLQDLElDLETRA----KDVKARLALLEVQEETARREKQQ 909
Cdd:TIGR02169  928 ALEEELSEIEDPKGEDEEIPEEEL--SLEDVQAELQRVEEEIRALE-PVNMLAiqeyEEVLKRLDELKEKRAKLEEERKA 1004


                   ...
gi 2217281769  910 LLD 912
Cdd:TIGR02169 1005 ILE 1007

PRK03918

DNA double-strand break repair ATPase Rad50;

644-1001

2.87e-08

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.54 E-value: 2.87e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  644 EASLQKLREELESQQK--AERASLEQKNRQMLEQLKE---EIEASEKSEQAALNA-AKEKALQQLREQLEGERKEAVatl 717
Cdd:PRK03918   313 EKRLSRLEEEINGIEEriKELEEKEERLEELKKKLKElekRLEELEERHELYEEAkAKKEELERLKKRLTGLTPEKL--- 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  718 eKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEA--QLQKCLGQV-----EHRVHQKSYHVAGYEHELSSLLREK 790
Cdd:PRK03918   390 -EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAieELKKAKGKCpvcgrELTEEHRKELLEEYTAELKRIEKEL 468

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  791 RqevegEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRaheRELEtvrqEQHKRLEDLRRRHRE 870
Cdd:PRK03918   469 K-----EIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNL---EELE----KKAEEYEKLKEKLIK 536

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  871 QERKLQDLELDLEtRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKS-EEATATHQQLEEAQKEHTHLLQSNQQLR 949
Cdd:PRK03918   537 LKGEIKSLKKELE-KLEELKKKLAELEKKLDELEEELAELLKELEELGFESvEELEERLKELEPFYNEYLELKDAEKELE 615

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2217281769  950 EILDELQarklKLESQVDLLQAQSQQLQKHFSSLEAEAQKkqhLLREVTVEE 1001
Cdd:PRK03918   616 REEKELK----KLEEELDKAFEELAETEKRLEELRKELEE---LEKKYSEEE 660

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

623-937

5.14e-08

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.77 E-value: 5.14e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  623 WLRAQVQSSTQADEDQIRAeQEASLQKLREELESQQKAERASLEQKNrQMLEQLKEEIEASEKSEQAALnaaKEKALQQL 702
Cdd:TIGR02169  226 YELLKEKEALERQKEAIER-QLASLEEELEKLTEEISELEKRLEEIE-QLLEELNKKIKDLGEEEQLRV---KEKIGELE 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  703 REQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEaQQKEEAQLQKCLGQVEHRVHQKSYHVAgyehE 782
Cdd:TIGR02169  301 AEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEE-ERKRRDKLTEEYAELKEELEDLRAELE----E 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  783 LSSLLREKRQEVEgEHERRLDKMKEEHQQVmaKAREQYEAEERKQRAELLGHLTGELERLQRAHeRELETvrqeqhkRLE 862
Cdd:TIGR02169  376 VDKEFAETRDELK-DYREKLEKLKREINEL--KRELDRLQEELQRLSEELADLNAAIAGIEAKI-NELEE-------EKE 444

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217281769  863 DLRRRHREQERKLQDLELDLEtrakdvKARLALLEVQEETARREKQqlldvQRQVALKSEEATATHQQLEEAQKE 937
Cdd:TIGR02169  445 DKALEIKKQEWKLEQLAADLS------KYEQELYDLKEEYDRVEKE-----LSKLQRELAEAEAQARASEERVRG 508

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

657-950

5.30e-08

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 56.47 E-value: 5.30e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  657 QQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEgerkeavatlEKEHSAELERLcssLEAKH 736
Cdd:pfam13868   33 RIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIE----------EREQKRQEEYE---EKLQE 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  737 REVVSSLQKKIQEAQQKEEAQLQKclgqvehRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKA 816
Cdd:pfam13868  100 REQMDEIVERIQEEDQAEAEEKLE-------KQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEERE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  817 REQYEAEERKQR-AELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDlETRAKDVKARLAL 895
Cdd:pfam13868  173 AEREEIEEEKEReIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQ-QAREEQIELKERR 251

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217281769  896 LEVQEETARREKQQLLDVQR-QVALKSEEATATHQQLEEAQKEHTHLLQSNQQLRE 950
Cdd:pfam13868  252 LAEEAEREEEEFERMLRKQAeDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRA 307

PRK03918

DNA double-strand break repair ATPase Rad50;

630-1148

6.88e-08

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 57.38 E-value: 6.88e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  630 SSTQADEDQIRAEQEASLQKLRE--ELESQQKAERASLE--QKNRQMLEQLKEEIEASEKSEQAALNAAK--EKALQQLR 703
Cdd:PRK03918   186 KRTENIEELIKEKEKELEEVLREinEISSELPELREELEklEKEVKELEELKEEIEELEKELESLEGSKRklEEKIRELE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  704 EQLEGERKE-------------------AVATLEKEHSAELERL--CSSLEAKHREVVSSLQKKIQEAQQKEE--AQLQK 760
Cdd:PRK03918   266 ERIEELKKEieeleekvkelkelkekaeEYIKLSEFYEEYLDELreIEKRLSRLEEEINGIEERIKELEEKEErlEELKK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  761 CLGQVEHRVHQKSYHVAGYEhELSSLLREKRQEVEGEHERRLDKMKEEHQQVmAKAREQYEAEERKQRAELlGHLTGELE 840
Cdd:PRK03918   346 KLKELEKRLEELEERHELYE-EAKAKKEELERLKKRLTGLTPEKLEKELEEL-EKAKEEIEEEISKITARI-GELKKEIK 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  841 RLQRAHErELETVRQ---------EQHKRLEDLRRRHREQERKLQDLElDLETRAKDVKARLALLEVQeetarREKQQLL 911
Cdd:PRK03918   423 ELKKAIE-ELKKAKGkcpvcgrelTEEHRKELLEEYTAELKRIEKELK-EIEEKERKLRKELRELEKV-----LKKESEL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  912 DVQRQVA--LKSEEATATHQQLEEAQKEHTHLlqsnQQLREILDELQARKLKLESQVdllqaqsqqlqkhfSSLEAEAQK 989
Cdd:PRK03918   496 IKLKELAeqLKELEEKLKKYNLEELEKKAEEY----EKLKEKLIKLKGEIKSLKKEL--------------EKLEELKKK 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  990 KQHLLREV-TVEENNASphfepdlhIEDLRKSLGTNQTKEVSSSLsQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFL 1068
Cdd:PRK03918   558 LAELEKKLdELEEELAE--------LLKELEELGFESVEELEERL-KELEPFYNEYLELKDAEKELEREEKELKKLEEEL 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1069 VQ----------QTRSMRRRQTALKAAQQHWRHE------LASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRK 1132
Cdd:PRK03918   629 DKafeelaetekRLEELRKELEELEKKYSEEEYEelreeyLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708

                          570
                   ....*....|....*.
gi 2217281769 1133 GHNLLKKKEEKLNQLE 1148
Cdd:PRK03918   709 AKKELEKLEKALERVE 724

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

509-910

1.13e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 56.65 E-value: 1.13e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  509 ELGEDSAASLSLQLSLQRRSTEPVAPPEQLSEAALkameEAVAQVLEQDQRHLLESKQekMQQLREKLcqeeeeeilrlh 588
Cdd:pfam05483  373 EKNEDQLKIITMELQKKSSELEEMTKFKNNKEVEL----EELKKILAEDEKLLDEKKQ--FEKIAEEL------------ 434

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  589 QQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIR-AEQEASLQKLR-EELESQQKAERASLE 666
Cdd:pfam05483  435 KGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKnIELTAHCDKLLlENKELTQEASDMTLE 514

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  667 QKNRQ------------MLEQLkEEIEASEKSEQAALNAAKEKALQQ-------LREQLEGERKEAVATLEKEHSAE-LE 726
Cdd:pfam05483  515 LKKHQediinckkqeerMLKQI-ENLEEKEMNLRDELESVREEFIQKgdevkckLDKSEENARSIEYEVLKKEKQMKiLE 593

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  727 RLCSSLeakhREVVSSLQKKIQEAQQKEEAQLQKC------LGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGE--- 797
Cdd:pfam05483  594 NKCNNL----KKQIENKNKNIEELHQENKALKKKGsaenkqLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKkis 669

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  798 HERRLDKMKEEHQQVMAKAREQYEAEERKQraellgHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQerklQD 877
Cdd:pfam05483  670 EEKLLEEVEKAKAIADEAVKLQKEIDKRCQ------HKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQ----SS 739

                          410       420       430
                   ....*....|....*....|....*....|...
gi 2217281769  878 LELDLETRAKDVKARLALLEVQEETARREKQQL 910
Cdd:pfam05483  740 AKAALEIELSNIKAELLSLKKQLEIEKEEKEKL 772

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

846-1163

1.17e-07

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.60 E-value: 1.17e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  846 HERELETVR-----QEQHKRLEDLRRrhrEQERKLQDLEL---------DLETRAKDVKARLALLEVQEETARRE--KQQ 909
Cdd:TIGR02168  171 KERRKETERklertRENLDRLEDILN---ELERQLKSLERqaekaerykELKAELRELELALLVLRLEELREELEelQEE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  910 LLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQK 989
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  990 KQHLLREVTVEENNASPHFEPDL-HIEDLRKSLGT-NQTKEVSSSLSQSKEDLYLDslsshnvwhlLSAEGVALRSAKEF 1067
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKeELESLEAELEElEAELEELESRLEELEEQLET----------LRSKVAQLELQIAS 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1068 LVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPpgikALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQL 1147
Cdd:TIGR02168  398 LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA----ELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330
                   ....*....|....*.
gi 2217281769 1148 ESSLWEEASDEGTLGG 1163
Cdd:TIGR02168  474 EQALDAAERELAQLQA 489

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

688-926

1.37e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.54 E-value: 1.37e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  688 QAALNAAKEKALQQLREQLEgERKEAVATLEKEHSAELERLcssleAKHREVVSSLQKKIQEAQQkEEAQLQKCLGQVEH 767
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIA-ELEKELAALKKEEKALLKQL-----AALERRIAALARRIRALEQ-ELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  768 RVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRahe 847
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA--- 167

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217281769  848 rELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATA 926
Cdd:COG4942    168 -ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245

rad50

TIGR00606

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

543-1162

4.09e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 55.05 E-value: 4.09e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  543 LKAMEEAVAQVLE-QDQRHLLESKQEKMQQLREKLCQEEEE----------EILRLHQQKEQSLSSLRERLQKAIEEEEA 611
Cdd:TIGR00606  254 LKEIEHNLSKIMKlDNEIKALKSRKKQMEKDNSELELKMEKvfqgtdeqlnDLYHNHQRTVREKERELVDCQRELEKLNK 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  612 RMREEESQRLSWLRAQVQSSTQAD--EDQIRAEQEASLQ-KLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQ 688
Cdd:TIGR00606  334 ERRLLNQEKTELLVEQGRLQLQADrhQEHIRARDSLIQSlATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  689 AALNAAKEKALQQLREQLEGERKEAVATLEKEhSAELERLCSSL-----EAKHREVVSSLQKKIQEAQQKEEAQLQKClg 763
Cdd:TIGR00606  414 CADLQSKERLKQEQADEIRDEKKGLGRTIELK-KEILEKKQEELkfvikELQQLEGSSDRILELDQELRKAERELSKA-- 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  764 QVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHErrLDKMKEEHQQVMAKAREQYEAEER------KQRAELLGHL-- 835
Cdd:TIGR00606  491 EKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQ--LNHHTTTRTQMEMLTKDKMDKDEQirkiksRHSDELTSLLgy 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  836 ---TGELERLQRAHERELETVR------QEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARlallEVQEETARRE 906
Cdd:TIGR00606  569 fpnKKQLEDWLHSKSKEINQTRdrlaklNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS----QDEESDLERL 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  907 KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAE 986
Cdd:TIGR00606  645 KEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKR 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  987 aqkKQHLLREVTVEENnasphfEPDLHIEDLRKSlgTNQTKEVSSSLSQSKEDLYLDSlsshnvwHLLSAEGVALRSAKE 1066
Cdd:TIGR00606  725 ---RDEMLGLAPGRQS------IIDLKEKEIPEL--RNKLQKVNRDIQRLKNDIEEQE-------TLLGTIMPEEESAKV 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1067 FLVQQTrSMRRRQTALKAAQQHWRHELASAQEVAKDppgiKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQ 1146
Cdd:TIGR00606  787 CLTDVT-IMERFQMELKDVERKIAQQAAKLQGSDLD----RTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQH 861

                          650
                   ....*....|....*.
gi 2217281769 1147 LESSLWEEASDEGTLG 1162
Cdd:TIGR00606  862 LKSKTNELKSEKLQIG 877

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

644-878

4.19e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 54.96 E-value: 4.19e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  644 EASLQKLRE---ELESQQKAERASlEQKNRQMLEQLKEEIEASEK-SEQAALNAAKEKA--LQQLREQLEgERKEAVATL 717
Cdd:COG3096    835 EAELAALRQrrsELERELAQHRAQ-EQQLRQQLDQLKEQLQLLNKlLPQANLLADETLAdrLEELREELD-AAQEAQAFI 912

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  718 EK--EHSAELERLCSSLEAKhREVVSSLQKKIQEAQQKEEAQLQKC--LGQVEHRVHQKSYHVA----GYEHELSSLLRE 789
Cdd:COG3096    913 QQhgKALAQLEPLVAVLQSD-PEQFEQLQADYLQAKEQQRRLKQQIfaLSEVVQRRPHFSYEDAvgllGENSDLNEKLRA 991

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  790 KRQEVEGEHERRLDKMK------EEHQQVMAKAREQYEAeerkqRAELLGHLTGELERL---------QRAHER------ 848
Cdd:COG3096    992 RLEQAEEARREAREQLRqaqaqySQYNQVLASLKSSRDA-----KQQTLQELEQELEELgvqadaeaeERARIRrdelhe 1066

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2217281769  849 ----------ELETVRQEQHKRLEDLRRRHREQERKLQDL 878
Cdd:COG3096   1067 elsqnrsrrsQLEKQLTRCEAEMDSLQKRLRKAERDYKQE 1106

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

778-1126

4.67e-07

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.69 E-value: 4.67e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  778 GYEHELSSLLREKRqEVEGEHERRLDKMKEEHQQV--MAKAREQYEAEERKQRAELlghltGELERLQRAHERELETVRQ 855
Cdd:TIGR02169  685 GLKRELSSLQSELR-RIENRLDELSQELSDASRKIgeIEKEIEQLEQEEEKLKERL-----EELEEDLSSLEQEIENVKS 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  856 EqhkrLEDLRRRHREQERKLQDLELDLEtrakDVKARLALLEVQEETARREKQQLlDVQRQVAlkseeatathqQLEEAQ 935
Cdd:TIGR02169  759 E----LKELEARIEELEEDLHKLEEALN----DLEARLSHSRIPEIQAELSKLEE-EVSRIEA-----------RLREIE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  936 KEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEennasphfepdlhIE 1015
Cdd:TIGR02169  819 QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR-------------LG 885

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1016 DLRKslgtnQTKEVSSSLSQSKEdlyldslsshnvwhllsaegvALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELAS 1095
Cdd:TIGR02169  886 DLKK-----ERDELEAQLRELER---------------------KIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939

                          330       340       350
                   ....*....|....*....|....*....|.
gi 2217281769 1096 AQEVAKDPPGIKALEDMRKNLEKETRHLDEM 1126
Cdd:TIGR02169  940 KGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

798-967

5.85e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.00 E-value: 5.85e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  798 HERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELEtvRQEQHKRLEDLRRRHREQERKLQD 877
Cdd:COG4717     66 PELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE--KLEKLLQLLPLYQELEALEAELAE 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  878 LEldleTRAKDVKARLALLEVQEETARREKQQLLDVQRQVA-LKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQ 956
Cdd:COG4717    144 LP----ERLEELEERLEELRELEEELEELEAELAELQEELEeLLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219

                          170
                   ....*....|.
gi 2217281769  957 ARKLKLESQVD 967
Cdd:COG4717    220 EELEELEEELE 230

PRK02224

DNA double-strand break repair Rad50 ATPase;

620-965

6.24e-07

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 54.28 E-value: 6.24e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  620 RLSWLRAQVQSSTQADEDQIRAEQEASLQKLREEL---ESQQKAERASLEQKN---------RQMLEQLKEEIEASEKSE 687
Cdd:PRK02224   188 SLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIeryEEQREQARETRDEADevleeheerREELETLEAEIEDLRETI 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  688 qaalnAAKEKALQQLREQLEgERKEAVATLEKEHSAELERlcSSLEAKHREVVSSLqkkiQEAQQKEEAQLQKCLGQVEH 767
Cdd:PRK02224   268 -----AETEREREELAEEVR-DLRERLEELEEERDDLLAE--AGLDDADAEAVEAR----REELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  768 RVHQKSYHVAGYEHELSSL------LREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEER-----KQRAELLGHLT 836
Cdd:PRK02224   336 AAQAHNEEAESLREDADDLeeraeeLREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdapVDLGNAEDFLE 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  837 GELERLQRAHER--ELETVRQEQHKRLEDLRR------------------------RHREQERKLQDLELDLETRAKDVK 890
Cdd:PRK02224   416 ELREERDELREReaELEATLRTARERVEEAEAlleagkcpecgqpvegsphvetieEDRERVEELEAELEDLEEEVEEVE 495

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217281769  891 ARLALLEVQEETARR---EKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREildelQARKLKLESQ 965
Cdd:PRK02224   496 ERLERAEDLVEAEDRierLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKRE-----AAAEAEEEAE 568

PRK02224

DNA double-strand break repair Rad50 ATPase;

661-957

7.27e-07

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 53.89 E-value: 7.27e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  661 ERAS--------LEQKNRQMLEQLKEEIEASEKSE-QAALNAAkEKALQQLREQL---EGERKEAVATLEK------EHS 722
Cdd:PRK02224   169 ERASdarlgverVLSDQRGSLDQLKAQIEEKEEKDlHERLNGL-ESELAELDEEIeryEEQREQARETRDEadevleEHE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  723 AELERLcSSLEAKHREvvssLQKKIQEAQQKEEaqlqkclgqvehrvhqksyhvagyehELSSLLREKRQEVEGEHERRL 802
Cdd:PRK02224   248 ERREEL-ETLEAEIED----LRETIAETERERE--------------------------ELAEEVRDLRERLEELEEERD 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  803 DKMKEehqqvmaKAREQYEAEERKQRAEllghltgELERLQRAHERELETVRQEQhkrledlrRRHREQERKLQDLELDL 882
Cdd:PRK02224   297 DLLAE-------AGLDDADAEAVEARRE-------ELEDRDEELRDRLEECRVAA--------QAHNEEAESLREDADDL 354

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217281769  883 ETRAKDVKARLALLEVQEETARRE----KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQA 957
Cdd:PRK02224   355 EERAEELREEAAELESELEEAREAvedrREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEA 433

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

551-893

8.52e-07

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 52.61 E-value: 8.52e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  551 AQVLEQDQRHLLESKQEK-----MQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLR 625
Cdd:pfam13868   26 AQIAEKKRIKAEEKEEERrldemMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  626 AQVQssTQADEDQIRAEQEASLQKLREELEsQQKAERASLEQKNRQMLEQL----------KEEIEASEKSEQAALNAAK 695
Cdd:pfam13868  106 IVER--IQEEDQAEAEEKLEKQRQLREEID-EFNEEQAEWKELEKEEEREEderileylkeKAEREEEREAEREEIEEEK 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  696 EKALQQLREQLEGERKEavatLEKEHSAELERLCSSLEAKHRevvsslQKKIQEAQQKEEAQLQKCLGQVEHRVHqksyh 775
Cdd:pfam13868  183 EREIARLRAQQEKAQDE----KAERDELRAKLYQEEQERKER------QKEREEAEKKARQRQELQQAREEQIEL----- 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  776 vagyehelssllREKRQEVEGEHERRLDKMKEEHQQVMAKaREQYEAEERKQRaellghltgelerlQRAHERELETVRQ 855
Cdd:pfam13868  248 ------------KERRLAEEAEREEEEFERMLRKQAEDEE-IEQEEAEKRRMK--------------RLEHRRELEKQIE 300

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 2217281769  856 EQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARL 893
Cdd:pfam13868  301 EREEQRAAEREEELEEGERLREEEAERRERIEEERQKK 338

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

621-856

8.66e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.84 E-value: 8.66e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  621 LSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQknrqmLEQLKEEIEASEK------SEQAALNA- 693
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ-----LAALERRIAALARriraleQELAALEAe 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  694 -----AKEKALQQLREQLEGERKEAVATLEKEHSA-ELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEH 767
Cdd:COG4942     85 laeleKEIAELRAELEAQKEELAELLRALYRLGRQpPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  768 RVHQKSYHVAgyehELSSLLREKRQEvegehERRLDKMKEEHQQVMAKAREQYEAEErkQRAELLGHLTGELERLQRAHE 847
Cdd:COG4942    165 LRAELEAERA----ELEALLAELEEE-----RAALEALKAERQKLLARLEKELAELA--AELAELQQEAEELEALIARLE 233


                   ....*....
gi 2217281769  848 RELETVRQE 856
Cdd:COG4942    234 AEAAAAAER 242

PRK12704

phosphodiesterase; Provisional

538-726

8.80e-07

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 53.24 E-value: 8.80e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  538 LSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKlcqeeeeeILRLHQQKEQSLSSLRERLQkaieeeearmreee 617
Cdd:PRK12704    28 IAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEE--------IHKLRNEFEKELRERRNELQ-------------- 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  618 sqrlswlraQVQSSTQADEDQIRAEQEaSLQKLREELESQQKaeraSLEQKNRQmLEQLKEEIEASEKSEQAAL----NA 693
Cdd:PRK12704    86 ---------KLEKRLLQKEENLDRKLE-LLEKREEELEKKEK----ELEQKQQE-LEKKEEELEELIEEQLQELerisGL 150

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2217281769  694 AKEKALQQLREQLEGE-RKEAVATL-EKEHSAELE 726
Cdd:PRK12704   151 TAEEAKEILLEKVEEEaRHEAAVLIkEIEEEAKEE 185

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

553-923

1.10e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.38 E-value: 1.10e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  553 VLEQDQRHLLESKQEKMQQLREKLcQEEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARMREEESQR-LSWLRAQVQSS 631
Cdd:COG4913    603 VLGFDNRAKLAALEAELAELEEEL-AEAEERLEALEAELDA-LQERREALQRLAEYSWDEIDVASAEReIAELEAELERL 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  632 TQADED-----QIRAEQEASLQKLREELEsQQKAERASLEQKnrqmLEQLKEEIEASekseQAALNAAKEKALQQLREQL 706
Cdd:COG4913    681 DASSDDlaaleEQLEELEAELEELEEELD-ELKGEIGRLEKE----LEQAEEELDEL----QDRLEAAEDLARLELRALL 751

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  707 EGERKEA-VATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgqvEHRVHQKSYHvaGYEHELSS 785
Cdd:COG4913    752 EERFAAAlGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETA------DLDADLESLP--EYLALLDR 823

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  786 LLREKRQEVEGEHERRLDKMKEEH----QQVMAKAREqyEAEERkqraelLGHLTGELERLQRAHERELE-TVRQEQHKR 860
Cdd:COG4913    824 LEEDGLPEYEERFKELLNENSIEFvadlLSKLRRAIR--EIKER------IDPLNDSLKRIPFGPGRYLRlEARPRPDPE 895

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217281769  861 LEDLRRRHREQERKLQDLELDL-ETRAKDVKARLALLEVQE-ETARREKQQLLDVQRQVALKSEE 923
Cdd:COG4913    896 VREFRQELRAVTSGASLFDEELsEARFAALKRLIERLRSEEeESDRRWRARVLDVRNHLEFDAEE 960

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

540-1156

1.13e-06

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 1.13e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  540 EAALKAMEEAVAQVLEQ--DQRHLLESKQEKMQQLREKLCQEEEEEILRLhQQKEQSLSSLRERLQKAIEEEEarmreee 617
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEisELEKRLEEIEQLLEELNKKIKDLGEEEQLRV-KEKIGELEAEIASLERSIAEKE------- 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  618 sQRLSWLRAQVQsstQADEDqiRAEQEASLQKLREELESQQKaERASLE---QKNRQMLEQLKEEIEASEKSEQAA---L 691
Cdd:TIGR02169  315 -RELEDAEERLA---KLEAE--IDKLLAEIEELEREIEEERK-RRDKLTeeyAELKEELEDLRAELEEVDKEFAETrdeL 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  692 NAAKEK--ALQQLREQLEGERKEAVATLEKEHS--AELERLCSSLEAKHREVVS---SLQKKIQEAQQKEEaQLQKCLGQ 764
Cdd:TIGR02169  388 KDYREKleKLKREINELKRELDRLQEELQRLSEelADLNAAIAGIEAKINELEEekeDKALEIKKQEWKLE-QLAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  765 VEHRVHQKSYHVAGYEHELSSLLRE-------KRQEVEGEHERR-------------------LDKMKEEHQ---QVMAK 815
Cdd:TIGR02169  467 YEQELYDLKEEYDRVEKELSKLQRElaeaeaqARASEERVRGGRaveevlkasiqgvhgtvaqLGSVGERYAtaiEVAAG 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  816 AREQY---EAEERKQRA-ELL-----GHLTGELERLQRAHERELETVRQ-----------EQHKRLE------------- 862
Cdd:TIGR02169  547 NRLNNvvvEDDAVAKEAiELLkrrkaGRATFLPLNKMRDERRDLSILSEdgvigfavdlvEFDPKYEpafkyvfgdtlvv 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  863 ---DLRRRHREQERkLQDLELDL-----------------ETRAKDVKARLALLEVQEETARREKQQLLD----VQRQVA 918
Cdd:TIGR02169  627 ediEAARRLMGKYR-MVTLEGELfeksgamtggsraprggILFSRSEPAELQRLRERLEGLKRELSSLQSelrrIENRLD 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  919 LKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVt 998
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL- 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  999 veENNASPHFEPDL--HIEDLRKSLGTNQtkEVSSSLSQSKEDLYLDSLSshnvwhllsaegvaLRSAKEFLVQQTRSMR 1076
Cdd:TIGR02169  785 --EARLSHSRIPEIqaELSKLEEEVSRIE--ARLREIEQKLNRLTLEKEY--------------LEKEIQELQEQRIDLK 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1077 RRQTALKAAQQHWRHELAS-AQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEA 1155
Cdd:TIGR02169  847 EQIKSIEKEIENLNGKKEElEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926


                   .
gi 2217281769 1156 S 1156
Cdd:TIGR02169  927 E 927

PRK12704

phosphodiesterase; Provisional

641-830

1.69e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.47 E-value: 1.69e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  641 AEQEASLQKLREELESQQKAERASLEQKnrQMLEQLKEEIEASEKSEQAALNAaKEKALQQLREQLEgERKEAvatLEKE 720
Cdd:PRK12704    36 AEEEAKRILEEAKKEAEAIKKEALLEAK--EEIHKLRNEFEKELRERRNELQK-LEKRLLQKEENLD-RKLEL---LEKR 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  721 hSAELERLCSSLEAKHREvvssLQKKIQEAQQKEEAQLQKCLgqvehrvhqksyHVAGYEHElssllrEKRQEVegeher 800
Cdd:PRK12704   109 -EEELEKKEKELEQKQQE----LEKKEEELEELIEEQLQELE------------RISGLTAE------EAKEIL------ 159

                          170       180       190
                   ....*....|....*....|....*....|
gi 2217281769  801 rLDKMKEEHQQVMAKAREQYEaEERKQRAE 830
Cdd:PRK12704   160 -LEKVEEEARHEAAVLIKEIE-EEAKEEAD 187

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

508-1005

1.71e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 52.87 E-value: 1.71e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  508 EELGEDSAASLSLQLslqrrstEPVAppeqlSEAALKAMEEAVAQVLEQDQRHLLESKQekmqqLREKLCQEEEEeiLRL 587
Cdd:pfam01576  110 EQLDEEEAARQKLQL-------EKVT-----TEAKIKKLEEDILLLEDQNSKLSKERKL-----LEERISEFTSN--LAE 170

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  588 HQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADE--DQIR------AEQEASLQKLREELES--- 656
Cdd:pfam01576  171 EEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDlqEQIAelqaqiAELRAQLAKKEEELQAala 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  657 ---QQKAERASLEQKNRQMLEQLKEEIEASEkSEQAALNAAkEKALQQLREQLEGERKEAVATL-----EKEHSAELERL 728
Cdd:pfam01576  251 rleEETAQKNNALKKIRELEAQISELQEDLE-SERAARNKA-EKQRRDLGEELEALKTELEDTLdttaaQQELRSKREQE 328

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  729 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKS---YHVAGYEHELSSLLREKR--QEVEGEHERRLD 803
Cdd:pfam01576  329 VTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKAnleKAKQALESENAELQAELRtlQQAKQDSEHKRK 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  804 KMKEEHQQVMAKAREQyeAEERKQRAELLGHLTGELERLQRAHErELETVRQEQHKRLEDLrrrhreqERKLQDLE--LD 881
Cdd:pfam01576  409 KLEGQLQELQARLSES--ERQRAELAEKLSKLQSELESVSSLLN-EAEGKNIKLSKDVSSL-------ESQLQDTQelLQ 478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  882 LETRAK------------DVKARLALLEVQEETARREKQQLLDVQRQVA---LKSEEATATHQQLEEAQKEHTHLLQS-N 945
Cdd:pfam01576  479 EETRQKlnlstrlrqledERNSLQEQLEEEEEAKRNVERQLSTLQAQLSdmkKKLEEDAGTLEALEEGKKRLQRELEAlT 558

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217281769  946 QQLRE---ILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEaeaqKKQHLLREVTVEENNAS 1005
Cdd:pfam01576  559 QQLEEkaaAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLE----KKQKKFDQMLAEEKAIS 617

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

536-1154

2.41e-06

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 52.28 E-value: 2.41e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  536 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMRE 615
Cdd:pfam02463  287 ELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQE 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  616 EESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAAL---- 691
Cdd:pfam02463  367 KLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKqgkl 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  692 ----NAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK---CLGQ 764
Cdd:pfam02463  447 teekEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGvggRIIS 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  765 VEHRVHQKSYHVAGYEHELSSL-----LREKRQEVEGEHERR---------------LDKMKEEHQQVMAKAREQYEAEE 824
Cdd:pfam02463  527 AHGRLGDLGVAVENYKVAISTAvivevSATADEVEERQKLVRaltelplgarklrllIPKLKLPLKSIAVLEIDPILNLA 606

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  825 RKQRAELLGHLTGELERLQRAHERE-LETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEetA 903
Cdd:pfam02463  607 QLDKATLEADEDDKRAKVVEGILKDtELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQE--K 684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  904 RREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQvDLLQAQSQQLQKHFSSL 983
Cdd:pfam02463  685 AESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKID-EEEEEEEKSRLKKEEKE 763

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  984 EAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLG-TNQTKEVSSSLSQSKEDLYLDSLSSH---NVWHLLSAEGV 1059
Cdd:pfam02463  764 EEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEElRALEEELKEEAELLEEEQLLIEQEEKikeEELEELALELK 843

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1060 ALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKK 1139
Cdd:pfam02463  844 EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          650
                   ....*....|....*
gi 2217281769 1140 KEEKLNQLESSLWEE 1154
Cdd:pfam02463  924 KEEAEILLKYEEEPE 938

PTZ00121

MAEBL; Provisional

677-1155

2.56e-06

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.45 E-value: 2.56e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  677 KEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAElerlcsslEAKHREVVsslqKKIQEAQQKEEA 756
Cdd:PTZ00121  1084 KEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAE--------EARKAEDA----RKAEEARKAEDA 1151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  757 QLQKCLGQVEhrvhqksyhvagyEHELSSLLREKRQEVEGEHERRLDKMKEEHQqvMAKAREQYEAEERKQRAELLghlt 836
Cdd:PTZ00121  1152 KRVEIARKAE-------------DARKAEEARKAEDAKKAEAARKAEEVRKAEE--LRKAEDARKAEAARKAEEER---- 1212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  837 gELERLQRAHE-RELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQR 915
Cdd:PTZ00121  1213 -KAEEARKAEDaKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKK 1291

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  916 QVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLR 995
Cdd:PTZ00121  1292 ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK 1371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  996 EVTVEENNASphfEPDLHIEDLRKSlgtNQTKEVSSSLSQSKEDLYLDSLSSHNVwHLLSAEGVALRSAKEfLVQQTRSM 1075
Cdd:PTZ00121  1372 KKEEAKKKAD---AAKKKAEEKKKA---DEAKKKAEEDKKKADELKKAAAAKKKA-DEAKKKAEEKKKADE-AKKKAEEA 1443

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1076 RRRQTALKAAQqhwrhELASAQEVAKDPPGIKALEDMRKNLEkETRHLDEMK----SAMRKGHNLLKKKEEKLNQLESSL 1151
Cdd:PTZ00121  1444 KKADEAKKKAE-----EAKKAEEAKKKAEEAKKADEAKKKAE-EAKKADEAKkkaeEAKKKADEAKKAAEAKKKADEAKK 1517


                   ....
gi 2217281769 1152 WEEA 1155
Cdd:PTZ00121  1518 AEEA 1521

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

558-760

2.91e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 2.91e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  558 QRHLLESKQEKMQQLREKLcqEEEEEILRLHQQKEQSLSSLRERLQKAIEeEEARMREEESQRLSWLRAQVQsSTQADED 637
Cdd:COG4942     18 QADAAAEAEAELEQLQQEI--AELEKELAALKKEEKALLKQLAALERRIA-ALARRIRALEQELAALEAELA-ELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  638 QIRAEQEASLQKLREELESQQKAERASLEQ------------KNRQMLEQLKEEIEaseksEQAALNAAKEKALQQLREQ 705
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldavRRLQYLKYLAPARR-----EQAEELRADLAELAALRAE 168

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2217281769  706 LEGERKEaVATLEKEHSAELERLcSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK 760
Cdd:COG4942    169 LEAERAE-LEALLAELEEERAAL-EALKAERQKLLARLEKELAELAAELAELQQE 221

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

438-966

3.39e-06

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 51.89 E-value: 3.39e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  438 RQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQspprslateEEPPQGPEGQPEWKEAEELGEDSAAS 517
Cdd:TIGR00618  239 QQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQ---------ERINRARKAAPLAAHIKAVTQIEQQA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  518 LSLQLSLQRRSTEPVAPPEQLSEAALKAMEEAVAQVLEQD---QRHLLESKQEKMQQLREKLCQEEEEE--ILRLHQQKE 592
Cdd:TIGR00618  310 QRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTlhsQEIHIRDAHEVATSIREISCQQHTLTqhIHTLQQQKT 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  593 ------QSLSSLRERLQK---------------AIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR 651
Cdd:TIGR00618  390 tltqklQSLCKELDILQReqatidtrtsafrdlQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLK 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  652 EELE--------SQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKE-KALQQLREQLEGERK---EAVATLEK 719
Cdd:TIGR00618  470 EREQqlqtkeqiHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNpGPLTRRMQRGEQTYAqleTSEEDVYH 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  720 EHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ-LQKCLGQVEHRVHQKSyhvagyEHELSSLLREKRQEVEGEH 798
Cdd:TIGR00618  550 QLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPnLQNITVRLQDLTEKLS------EAEDMLACEQHALLRKLQP 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  799 ERRL--------DKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQR--AHERELE----------------- 851
Cdd:TIGR00618  624 EQDLqdvrlhlqQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASrqLALQKMQsekeqltywkemlaqcq 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  852 TVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKdvkarlALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQL 931
Cdd:TIGR00618  704 TLLRELETHIEEYDREFNEIENASSSLGSDLAARED------ALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTG 777

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 2217281769  932 EEAQkehtHLLQSNQQLREILDELQARKLKLESQV 966
Cdd:TIGR00618  778 AELS----HLAAEIQFFNRLREEDTHLLKTLEAEI 808

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

625-985

4.31e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 51.49 E-value: 4.31e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  625 RAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERAsLE---QKNRQMLEQLKEEIEASEKSE--QAALNAAKEKAL 699
Cdd:COG3096    286 RALELRRELFGARRQLAEEQYRLVEMARELEELSARESD-LEqdyQAASDHLNLVQTALRQQEKIEryQEDLEELTERLE 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  700 QQ--LREQLEGERKEAVATLEkEHSAELERLCSSLeAKHREVVSSLQKKIQEAQQKEEAqlqkcLGQVEHRVHQKSYHVA 777
Cdd:COG3096    365 EQeeVVEEAAEQLAEAEARLE-AAEEEVDSLKSQL-ADYQQALDVQQTRAIQYQQAVQA-----LEKARALCGLPDLTPE 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  778 GYEHELSSLlREKRQEVegeHERRLDKmkEEHQQVMAKAREQYEaeerkQRAELLGHLTGELERLQrAHERELETVR--- 854
Cdd:COG3096    438 NAEDYLAAF-RAKEQQA---TEEVLEL--EQKLSVADAARRQFE-----KAYELVCKIAGEVERSQ-AWQTARELLRryr 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  855 --QEQHKRLEDLRRRHREQERKL---QDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQ 929
Cdd:COG3096    506 sqQALAQRLQQLRAQLAELEQRLrqqQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQ 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  930 QLEEAQKEHTHL------------------------LQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEA 985
Cdd:COG3096    586 QLEQLRARIKELaarapawlaaqdalerlreqsgeaLADSQEVTAAMQQLLEREREATVERDELAARKQALESQIERLSQ 665

cd00201

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ...

59-89

4.90e-06

Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 44.44 E-value: 4.90e-06

                           10        20        30
                   ....*....|....*....|....*....|.
gi 2217281769   59 PGEWKPCQDITGDIYYFNFANGQSMWDHPCD 89
Cdd:cd00201      1 PPGWEERWDPDGRVYYYNHNTKETQWEDPRE 31

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

743-1150

5.28e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.92 E-value: 5.28e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  743 LQKKIQEAQQKEE--AQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQ----EVEGEHERRLDKMKEEHQQVMAKA 816
Cdd:COG4717     76 LEEELKEAEEKEEeyAELQEELEELEEELEELEAELEELREELEKLEKLLQLlplyQELEALEAELAELPERLEELEERL 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  817 REQYEAEERKQRAEllghltGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLET---RAKDVKARL 893
Cdd:COG4717    156 EELRELEEELEELE------AELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEaqeELEELEEEL 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  894 ALLEVQEETArREKQQLLDVQRQVALKSE--EATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQvdllqa 971
Cdd:COG4717    230 EQLENELEAA-ALEERLKEARLLLLIAAAllALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGK------ 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  972 qsqqlqkhfSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGT-NQTKEVSSSLSQSKEDLYLDSLSSHNV 1050
Cdd:COG4717    303 ---------EAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRiEELQELLREAEELEEELQLEELEQEIA 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1051 wHLLSAEGVALRSAKEFLVQQTrsmrRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAM 1130
Cdd:COG4717    374 -ALLAEAGVEDEEELRAALEQA----EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEEL 448

                          410       420
                   ....*....|....*....|
gi 2217281769 1131 RKGHNLLKKKEEKLNQLESS 1150
Cdd:COG4717    449 EELREELAELEAELEQLEED 468

PRK12704

phosphodiesterase; Provisional

799-964

5.29e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.93 E-value: 5.29e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  799 ERRLDKMKEEHQQVMAKAREqyEAEERKQRAELlghltgelerlqrahereleTVRQEQHKRLEDLRRRHREQERKLQDL 878
Cdd:PRK12704    30 EAKIKEAEEEAKRILEEAKK--EAEAIKKEALL--------------------EAKEEIHKLRNEFEKELRERRNELQKL 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  879 EldletraKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHthllqsNQQLREI--LDELQ 956
Cdd:PRK12704    88 E-------KRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQ------LQELERIsgLTAEE 154


                   ....*...
gi 2217281769  957 ARKLKLES 964
Cdd:PRK12704   155 AKEILLEK 162

PRK12704

phosphodiesterase; Provisional

776-954

5.52e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.93 E-value: 5.52e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  776 VAGYEHELSSLLREKRQEVEGEHERRLDKMKEEhqqvMAKAREQYEAEERKQRAELlghltGELERLQRAHERELEtvrq 855
Cdd:PRK12704    33 IKEAEEEAKRILEEAKKEAEAIKKEALLEAKEE----IHKLRNEFEKELRERRNEL-----QKLEKRLLQKEENLD---- 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  856 eqhKRLEDLRRRhreqERKLQDLELDLETRAKDVKARlallevQEETARREKQQLLDVQRQVALKSEEATAthQQLEEAQ 935
Cdd:PRK12704   100 ---RKLELLEKR----EEELEKKEKELEQKQQELEKK------EEELEELIEEQLQELERISGLTAEEAKE--ILLEKVE 164

                          170
                   ....*....|....*....
gi 2217281769  936 KEHTHllQSNQQLREILDE 954
Cdd:PRK12704   165 EEARH--EAAVLIKEIEEE 181

PRK00106

ribonuclease Y;

626-824

5.60e-06

ribonuclease Y;

Pssm-ID: 178867 [Multi-domain] Cd Length: 535 Bit Score: 50.64 E-value: 5.60e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  626 AQVQSSTQADEDQIRAEQEAslQKLREELESQQKAERasleQKNRQMLEQLKEEIEASEKSEQAALNaaKEKALQQLREQ 705
Cdd:PRK00106    62 AKRESKALKKELLLEAKEEA--RKYREEIEQEFKSER----QELKQIESRLTERATSLDRKDENLSS--KEKTLESKEQS 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  706 LE------GERKEAVATLEKEHSAELERLCSSLEAKHREVVsslqkkiqeaqqkeeaqlqkcLGQVEHRVhqksyhvagy 779
Cdd:PRK00106   134 LTdkskhiDEREEQVEKLEEQKKAELERVAALSQAEAREII---------------------LAETENKL---------- 182

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2217281769  780 EHELSSLLREKRQEVegehERRLDKM-KEEHQQVMAKAREQYEAEE 824
Cdd:PRK00106   183 THEIATRIREAEREV----KDRSDKMaKDLLAQAMQRLAGEYVTEQ 224

mukB

chromosome partition protein MukB;

644-967

7.44e-06

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 50.73 E-value: 7.44e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  644 EASLQKLREELESQQKAERASLEQK--NRQMLEQLKEEIEaSEKSE----QAALNAAKEKALQQlreqlegerKEAVATL 717
Cdd:PRK04863   354 QADLEELEERLEEQNEVVEEADEQQeeNEARAEAAEEEVD-ELKSQladyQQALDVQQTRAIQY---------QQAVQAL 423

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  718 EKehsaeLERLC--SSLEAKhrevvsSLQKKIQEAQQKEEAQLQKCLgQVEHRVHQKSYHVAGYEHELSSLLRekrqeVE 795
Cdd:PRK04863   424 ER-----AKQLCglPDLTAD------NAEDWLEEFQAKEQEATEELL-SLEQKLSVAQAAHSQFEQAYQLVRK-----IA 486

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  796 GEHERrldkmKEEHQQVMAKAREqyeAEERKQRAELLGHLTGELERLQRahereletvRQEQHKRLEDLRR-------RH 868
Cdd:PRK04863   487 GEVSR-----SEAWDVARELLRR---LREQRHLAEQLQQLRMRLSELEQ---------RLRQQQRAERLLAefckrlgKN 549

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  869 REQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQL-LDVQR-----------QVAL-----KSEEATATHQQL 931
Cdd:PRK04863   550 LDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLqARIQRlaarapawlaaQDALarlreQSGEEFEDSQDV 629

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 2217281769  932 EEAQKEHTHLLQSNQQLReilDELQARKLKLESQVD 967
Cdd:PRK04863   630 TEYMQQLLERERELTVER---DELAARKQALDEEIE 662

PspA_IM30

pfam04012

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ...

637-763

7.80e-06

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.

Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 48.52 E-value: 7.80e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  637 DQIRAEQEASLQKLREELEsQQKAERASLEQKnrqmLEQLKEEIEASEKSEQAALNAAKE----KALQQlREQLEG--ER 710
Cdd:pfam04012   28 EQAIRDMQSELVKARQALA-QTIARQKQLERR----LEQQTEQAKKLEEKAQAALTKGNEelarEALAE-KKSLEKqaEA 101

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2217281769  711 KEAVATLEKEHSAELERLCSSLEAKHREVVSSLQK-KIQEAQQKEEAQLQKCLG 763
Cdd:pfam04012  102 LETQLAQQRSAVEQLRKQLAALETKIQQLKAKKNLlKARLKAAKAQEAVQTSLG 155

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

441-754

7.88e-06

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 50.53 E-value: 7.88e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  441 QQPLGIEDKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL 520
Cdd:pfam09731   57 LAPKPKTFRPLQPSVVSAVTGESKEPKEEKKQVKIPRQSGVSSEVAEEEKEATKDAAEAKAQLPKSEQEKEKALEEVLKE 136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  521 QLSLQRRSTEPVAPPE----QLSEAALKAMEEAVAQVLEQDQ------RHLLESKQEKMQQLREKLCQEEEEEILRLHQQ 590
Cdd:pfam09731  137 AISKAESATAVAKEAKddaiQAVKAHTDSLKEASDTAEISREkatdsaLQKAEALAEKLKEVINLAKQSEEEAAPPLLDA 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  591 KEQSLSSLRERLQKAIEEEEArmreeeSQRLSWLRAQVQSSTqADEDQIRAEQEAS------------------------ 646
Cdd:pfam09731  217 APETPPKLPEHLDNVEEKVEK------AQSLAKLVDQYKELV-ASERIVFQQELVSifpdiipvlkednllsnddlnsli 289

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  647 ------LQKLREELESQQKAERASLEQKnrqmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKE 720
Cdd:pfam09731  290 ahahreIDQLSKKLAELKKREEKHIERA----LEKQKEELDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEK 365

                          330       340       350
                   ....*....|....*....|....*....|....
gi 2217281769  721 HSAELERLCSSLEAKHREVVSSLQKKIQEAQQKE 754
Cdd:pfam09731  366 LRTELERQAEAHEEHLKDVLVEQEIELQREFLQD 399

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

787-990

8.52e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 8.52e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  787 LREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEER-KQRAELLGHLTGELERLQR---AHERELETVRQEQHKRLE 862
Cdd:COG4942     25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiAALARRIRALEQELAALEAelaELEKEIAELRAELEAQKE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  863 DLRRRHREQERKLQDLELDLETRAKDVKA---RLALL----EVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQ 935
Cdd:COG4942    105 ELAELLRALYRLGRQPPLALLLSPEDFLDavrRLQYLkylaPARREQAEELRADLAELAALRAELEAERAELEALLAELE 184

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2217281769  936 KEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKK 990
Cdd:COG4942    185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239

mukB

chromosome partition protein MukB;

641-891

8.66e-06

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 50.73 E-value: 8.66e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  641 AEQEASLQKLREELeSQQKAERASLEQKNRQM---LEQLKEEIEASEKSE-QAAL--NAAKEKALQQLREQLEgERKEAV 714
Cdd:PRK04863   833 ADPEAELRQLNRRR-VELERALADHESQEQQQrsqLEQAKEGLSALNRLLpRLNLlaDETLADRVEEIREQLD-EAEEAK 910

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  715 ATLEK--EHSAELERLCSSLEAKHREVvSSLQKKIQEAQQKEEAQLQKC--LGQVEHRVHQKSYHVA----GYEHELSSL 786
Cdd:PRK04863   911 RFVQQhgNALAQLEPIVSVLQSDPEQF-EQLKQDYQQAQQTQRDAKQQAfaLTEVVQRRAHFSYEDAaemlAKNSDLNEK 989

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  787 LREKRQEVEGEherrLDKMKEEHQQ----------VMAKAREQYEA-----EERKQRAELLG-HLTGELERLQRAHEREL 850
Cdd:PRK04863   990 LRQRLEQAEQE----RTRAREQLRQaqaqlaqynqVLASLKSSYDAkrqmlQELKQELQDLGvPADSGAEERARARRDEL 1065

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 2217281769  851 etvrqeqHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA 891
Cdd:PRK04863  1066 -------HARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRK 1099

PRK03918

DNA double-strand break repair ATPase Rad50;

738-1154

9.10e-06

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.45 E-value: 9.10e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  738 EVVSSLQKKIQEAQQ--KEEAQLQKCLGQVEHRVHQKSYHVagyeHELSSLLREKRQEVEGEHER--RLDKMKEEhqqvM 813
Cdd:PRK03918   169 EVIKEIKRRIERLEKfiKRTENIEELIKEKEKELEEVLREI----NEISSELPELREELEKLEKEvkELEELKEE----I 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  814 AKAREQYEAEERKQRA--ELLGHLTGELERLqRAHERELETVRQE---------QHKRLEDLRRRHREQERKLQDLELDL 882
Cdd:PRK03918   241 EELEKELESLEGSKRKleEKIRELEERIEEL-KKEIEELEEKVKElkelkekaeEYIKLSEFYEEYLDELREIEKRLSRL 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  883 ETRAKDVKARLALLEVQEETARREKQQLLDVQRQV------ALKSEEATATHQQLEEAQKEHTHLlqSNQQLREILDELQ 956
Cdd:PRK03918   320 EEEINGIEERIKELEEKEERLEELKKKLKELEKRLeeleerHELYEEAKAKKEELERLKKRLTGL--TPEKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  957 ARKLKLESQVDLLQAQSQQLQKHFSSLEA------EAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLgtnqtKEVS 1030
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKaieelkKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKEL-----KEIE 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1031 SSLSQSKEDLyldslsshnvwhllsaegvalRSAKEFLVQQTRSMRRRQTA--LKAAQQHWR-HELASAQEVAKDPPGIK 1107
Cdd:PRK03918   473 EKERKLRKEL---------------------RELEKVLKKESELIKLKELAeqLKELEEKLKkYNLEELEKKAEEYEKLK 531

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2217281769 1108 ----ALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEE 1154
Cdd:PRK03918   532 ekliKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEEL 582

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

638-754

9.41e-06

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 50.21 E-value: 9.41e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  638 QIRAEQEA-SLQKLREELESQQKaeraSLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVAT 716
Cdd:PRK00409   529 ERELEQKAeEAEALLKEAEKLKE----ELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYASV 604

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 2217281769  717 LEKEHSAELERLCSSLEAKHREvvsslqKKIQEAQQKE 754
Cdd:PRK00409   605 KAHELIEARKRLNKANEKKEKK------KKKQKEKQEE 636

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

543-913

1.04e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.22 E-value: 1.04e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  543 LKAMEEAVAQ------VLEQDQRHLLESKQEKMQQLREKLCQ-----EEEEEILRLHQQKEQSLSSLRERLQKAIEEEEA 611
Cdd:pfam12128  310 LSAADAAVAKdrseleALEDQHGAFLDADIETAAADQEQLPSwqselENLEERLKALTGKHQDVTAKYNRRRSKIKEQNN 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  612 RMREEESQRLSWLR-------AQVQSSTQADEDQIRAEQEASLQKLREE-LESQQKAERASLEQKNRQMLEQLKEEIEAS 683
Cdd:pfam12128  390 RDIAGIKDKLAKIReardrqlAVAEDDLQALESELREQLEAGKLEFNEEeYRLKSRLGELKLRLNQATATPELLLQLENF 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  684 E------KSEQAALNAAKEkALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHreVVSSLQKKIQEAQQKEEAQ 757
Cdd:pfam12128  470 DerieraREEQEAANAEVE-RLQSELRQARKRRDQASEALRQASRRLEERQSALDELEL--QLFPQAGTLLHFLRKEAPD 546

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  758 LQKCLGQVE-----HRVHQKSYHVAGYEHELSSL----LREKRQEV------EGEHERRLDKMKEEHQQVMAKAREQYEA 822
Cdd:pfam12128  547 WEQSIGKVIspellHRTDLDPEVWDGSVGGELNLygvkLDLKRIDVpewaasEEELRERLDKAEEALQSAREKQAAAEEQ 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  823 eerkqraelLGHLTGELERLQRAHERELETV--------------RQEQHKRLEDLRRRHREQERKLQDLELDLETRAKD 888
Cdd:pfam12128  627 ---------LVQANGELEKASREETFARTALknarldlrrlfdekQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKK 697

                          410       420
                   ....*....|....*....|....*
gi 2217281769  889 VKARLALLEVQEETARREKQQLLDV 913
Cdd:pfam12128  698 HQAWLEEQKEQKREARTEKQAYWQV 722

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

626-757

1.12e-05

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 49.46 E-value: 1.12e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  626 AQVQSSTQADEDQIRAEQEAslQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQ 705
Cdd:TIGR02794   50 QQANRIQQQKKPAAKKEQER--QKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAK 127

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217281769  706 LEGERK-------EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ 757
Cdd:TIGR02794  128 QAAEAKakaeaeaERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAE 186

HEC1

COG5185

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...

631-921

1.16e-05

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 49.96 E-value: 1.16e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  631 STQADEDQI-RAEQEASLQKLREELESQQKAERASLEQKNRQMLEQL------KEEIEASEKSEQAA---------LNAA 694
Cdd:COG5185    310 ATESLEEQLaAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLeaikeeIENIVGEVELSKSSeeldsfkdtIEST 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  695 KEKALQQLREQlEGERKEAVATLE---KEHSAELERLCSSLEAKHREVvsslqkkiqEAQQKEEAQLQKCLGQVEHRVhq 771
Cdd:COG5185    390 KESLDEIPQNQ-RGYAQEILATLEdtlKAADRQIEELQRQIEQATSSN---------EEVSKLLNELISELNKVMREA-- 457

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  772 ksyhvagyEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREqyeaeerkqraellghLTGELERLQRAHERELE 851
Cdd:COG5185    458 --------DEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVST----------------LKATLEKLRAKLERQLE 513

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217281769  852 TVRQEQHKRLEDLRRRHREQErklQDLELDLETRAKDVKARLALLE--VQEETARREKQQLLDVQRQVALKS 921
Cdd:COG5185    514 GVRSKLDQVAESLKDFMRARG---YAHILALENLIPASELIQASNAktDGQAANLRTAVIDELTQYLSTIES 582

pfam00397

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ...

58-87

1.21e-05

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro.

Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 43.26 E-value: 1.21e-05

                           10        20        30
                   ....*....|....*....|....*....|
gi 2217281769   58 LPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:pfam00397    1 LPPGWEERWDPDGRVYYYNHETGETQWEKP 30

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

718-996

1.31e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.74 E-value: 1.31e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  718 EKEHSAELERLCSSLEAKHREVvsSLQKKIQEAQQKEEAQLQKclgqvehrvhQKSYHVagyEHELSSLlrekrqevegE 797
Cdd:pfam17380  291 EKFEKMEQERLRQEKEEKAREV--ERRRKLEEAEKARQAEMDR----------QAAIYA---EQERMAM----------E 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  798 HERRLDKMK-EEHQQVMAKAREQYEAEERKQraellghlTGELERLQRAHERELETVRQE-----QHKRLEDLRRRHREQ 871
Cdd:pfam17380  346 RERELERIRqEERKRELERIRQEEIAMEISR--------MRELERLQMERQQKNERVRQEleaarKVKILEEERQRKIQQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  872 ERKLQDleldlETRAKDVKARLALLEVQEETARREKQQLldvqRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI 951
Cdd:pfam17380  418 QKVEME-----QIRAEQEEARQREVRRLEEERAREMERV----RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKR 488

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 2217281769  952 LDELqaRKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLRE 996
Cdd:pfam17380  489 AEEQ--RRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYE 531

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

540-801

2.18e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 48.97 E-value: 2.18e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  540 EAALKAMEEAVAQVLEQD-QRHLLESKQEKMQQLREKLCQEEEEEIL---RLHQQKEQSLSSLRERL-----QKAIEEEE 610
Cdd:pfam17380  332 QAAIYAEQERMAMERERElERIRQEERKRELERIRQEEIAMEISRMReleRLQMERQQKNERVRQELeaarkVKILEEER 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  611 ARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR-EELESQQKAE--RASLEQKNRQMLEQLKEEIEASEKSE 687
Cdd:pfam17380  412 QRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRlEEQERQQQVErlRQQEEERKRKKLELEKEKRDRKRAEE 491

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  688 QAALNAAKEKALQQlREQLEGERKEAVatLEKEhsaelerlcssLEAKHREVVSSLQKKIQEAQQKEEAQLQKclgqvEH 767
Cdd:pfam17380  492 QRRKILEKELEERK-QAMIEEERKRKL--LEKE-----------MEERQKAIYEEERRREAEEERRKQQEMEE-----RR 552

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 2217281769  768 RVHQKSYHVAGYEHELSSLLREK---RQEVEGEHERR 801
Cdd:pfam17380  553 RIQEQMRKATEERSRLEAMERERemmRQIVESEKARA 589

tolA

PRK09510

cell envelope integrity inner membrane protein TolA; Provisional

625-760

2.35e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 48.26 E-value: 2.35e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  625 RAQVQSSTQADEDQIR--AEQEASLQKLREELESQQKAERAslEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKAlqql 702
Cdd:PRK09510    80 QRKKKEQQQAEELQQKqaAEQERLKQLEKERLAAQEQKKQA--EEAAKQAALKQKQAEEAAAKAAAAAKAKAEAEA---- 153

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2217281769  703 rEQLEGERKEAVATLEKEHSAELERLCSSlEAKHREVVSSLQKKIQEAQQKEEAQLQK 760
Cdd:PRK09510   154 -KRAAAAAKKAAAEAKKKAEAEAAKKAAA-EAKKKAEAEAAAKAAAEAKKKAEAEAKK 209

smart00456

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...

57-87

2.99e-05

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.

Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 42.20 E-value: 2.99e-05

                            10        20        30
                    ....*....|....*....|....*....|.
gi 2217281769    57 PLPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:smart00456    1 PLPPGWEERKDPDGRPYYYNHETKETQWEKP 31

PLN03229

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional

524-797

3.12e-05

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional

Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 48.70 E-value: 3.12e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  524 LQRRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESK--QEKMQQLREKLCQEEEE----------EILRLHQQK 591
Cdd:PLN03229   441 LKEQILKAKESSSKPSELALNEMIEKLKKEIDLEYTEAVIAMglQERLENLREEFSKANSQdqlmhpvlmeKIEKLKDEF 520

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  592 EQSLS------SLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDqiRAEQEASLQKLREELESQQKAERASL 665
Cdd:PLN03229   521 NKRLSrapnylSLKYKLDMLNEFSRAKALSEKKSKAEKLKAEINKKFKEVMD--RPEIKEKMEALKAEVASSGASSGDEL 598

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  666 EQKNRQMLEQLKEEIEASE----KSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHRevVS 741
Cdd:PLN03229   599 DDDLKEKVEKMKKEIELELagvlKSMGLEVIGVTKKNKDTAEQTPPPNLQEKIESLNEEINKKIERVIRSSDLKSK--IE 676

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217281769  742 SLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGyehelSSLLREKRQEVEGE 797
Cdd:PLN03229   677 LLKLEVAKASKTPDVTEKEKIEALEQQIKQKIAEALN-----SSELKEKFEELEAE 727

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

824-1104

3.31e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.76 E-value: 3.31e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  824 ERKQRAELLGHLTGELERLQRAHErELETVRqEQHKRLEDLRRRHREQERKLQDLEL--DLETRAKDVKA--RLALLEVQ 899
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHE-ALEDAR-EQIELLEPIRELAERYAAARERLAEleYLRAALRLWFAqrRLELLEAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  900 EETARREKQQLldvQRQVALKSEEATATHQQLEEAQKEHthLLQSNQQLREILDELQARKLKLESQvdllqaqsqqlqkh 979
Cdd:COG4913    297 LEELRAELARL---EAELERLEARLDALREELDELEAQI--RGNGGDRLEQLEREIERLERELEER-------------- 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  980 fsslEAEAQKKQHLLREVtveennaspHFEPDLHIEDLRKSLgtNQTKEVSSSLSQSKEDLyldslssHNVWHLLSAEGV 1059
Cdd:COG4913    358 ----ERRRARLEALLAAL---------GLPLPASAEEFAALR--AEAAALLEALEEELEAL-------EEALAEAEAALR 415

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 2217281769 1060 ALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPP 1104
Cdd:COG4913    416 DLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAEL 460

PRK10929

putative mechanosensitive channel protein; Provisional

621-989

3.42e-05

putative mechanosensitive channel protein; Provisional

Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 48.51 E-value: 3.42e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  621 LSWLRAQ-VQSSTQADEDQIRAE-QEASLQKlreeleSQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAakEKA 698
Cdd:PRK10929     9 MAWLLSWgAYAATAPDEKQITQElEQAKAAK------TPAQAEIVEALQSALNWLEERKGSLERAKQYQQVIDNF--PKL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  699 LQQLREQLEGERKE--------AVATLEKE------HSAELERLCSSLEAKHREVVSSLQkkiQEAQQKEEAqlQKCLGQ 764
Cdd:PRK10929    81 SAELRQQLNNERDEprsvppnmSTDALEQEilqvssQLLEKSRQAQQEQDRAREISDSLS---QLPQQQTEA--RRQLNE 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  765 VEHRVH-------------------QKSYHVAGY-EHELSSLLREKRQEVEgehERRLDKMKEEHQQVMAK--------- 815
Cdd:PRK10929   156 IERRLQtlgtpntplaqaqltalqaESAALKALVdELELAQLSANNRQELA---RLRSELAKKRSQQLDAYlqalrnqln 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  816 AREQYEAEERKQRAELLGHLTGEL-----ERLQRahERELETVRQEQHKRLEDLRRRHReqerklqdleldlETRAKDVK 890
Cdd:PRK10929   233 SQRQREAERALESTELLAEQSGDLpksivAQFKI--NRELSQALNQQAQRMDLIASQQR-------------QAASQTLQ 297

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  891 ARLALlevqeeTARREKQQLLDVQRQV--ALKSEEAtathqQLEEAQKEhthllqsnQQLREILDELQARKLKLESQVDL 968
Cdd:PRK10929   298 VRQAL------NTLREQSQWLGVSNALgeALRAQVA-----RLPEMPKP--------QQLDTEMAQLRVQRLRYEDLLNK 358

                          410       420
                   ....*....|....*....|.
gi 2217281769  969 LQAQSQQLQKHFSSLEAEAQK 989
Cdd:PRK10929   359 QPQLRQIRQADGQPLTAEQNR 379

DUF4659

pfam15558

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...

672-923

4.65e-05

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.

Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 47.34 E-value: 4.65e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  672 MLEQLKEEIEASEKSEQAALNAAKEK-ALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEA 750
Cdd:pfam15558   13 MLARHKEEQRMRELQQQAALAWEELRrRDQKRQETLERERRLLLQQSQEQWQAEKEQRKARLGREERRRADRREKQVIEK 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  751 QQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKrqevegehERRLDKMKEEHQQVMAKAREQyeAEERKQRAE 830
Cdd:pfam15558   93 ESRWREQAEDQENQRQEKLERARQEAEQRKQCQEQRLKEK--------EEELQALREQNSLQLQERLEE--ACHKRQLKE 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  831 LLGHLTGELERLQraherelETVRQEQHKRLEDLRRRHREQERKLqDLELDLeTRAKDVKARLALLEVQE--ETARREKQ 908
Cdd:pfam15558  163 REEQKKVQENNLS-------ELLNHQARKVLVDCQAKAEELLRRL-SLEQSL-QRSQENYEQLVEERHRElrEKAQKEEE 233

                          250
                   ....*....|....*
gi 2217281769  909 QLLDVQRQVALKSEE 923
Cdd:pfam15558  234 QFQRAKWRAEEKEEE 248

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

637-830

5.04e-05

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 48.29 E-value: 5.04e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  637 DQIRAEQEASLQ--KLREELESQQKAERASLEQK----NRQMLEQLKEEIEASEKSEQAALNAAKEKAL----QQLREQL 706
Cdd:NF012221  1532 DNVVATSESSQQadAVSKHAKQDDAAQNALADKEraeaDRQRLEQEKQQQLAAISGSQSQLESTDQNALetngQAQRDAI 1611

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  707 EGERKEAVATLEK------------EHSAEL---------ERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgQV 765
Cdd:NF012221  1612 LEESRAVTKELTTlaqgldaldsqaTYAGESgdqwrnpfaGGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQ----KV 1687

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217281769  766 EHRVHQKSYHVA-GYEHELSSLLREKRQEVEGEhERRLDKMKEEHQQVMAKAREQYEAEERKQRAE 830
Cdd:NF012221  1688 KDAVAKSEAGVAqGEQNQANAEQDIDDAKADAE-KRKDDALAKQNEAQQAESDANAAANDAQSRGE 1752

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

787-958

5.27e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 5.27e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  787 LREKRQEVEGEH---ERRLDKMKEEHQQvMAKAREQYEAEERKQRAEL--------LGHLTGELERLQRAHE--RELETV 853
Cdd:COG4913    615 LEAELAELEEELaeaEERLEALEAELDA-LQERREALQRLAEYSWDEIdvasaereIAELEAELERLDASSDdlAALEEQ 693

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  854 RQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEE 933
Cdd:COG4913    694 LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEE 773

                          170       180
                   ....*....|....*....|....*.
gi 2217281769  934 AQ-KEHTHLLQSNQQLREILDELQAR 958
Cdd:COG4913    774 RIdALRARLNRAEEELERAMRAFNRE 799

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

554-966

6.01e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 47.71 E-value: 6.01e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  554 LEQDQRHLLESKQEKMQQLREKlcqeeeEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEeSQRLSWLRAQVQSSTQ 633
Cdd:TIGR04523  223 LKKQNNQLKDNIEKKQQEINEK------TTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN-NKKIKELEKQLNQLKS 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  634 ADEDQIRAEQEASLQKLREELESQQKAERASLEQ--KNRQMLEQLKEEIEASEKSEQAalnaaKEKALQQLREQLEgERK 711
Cdd:TIGR04523  296 EISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQisQNNKIISQLNEQISQLKKELTN-----SESENSEKQRELE-EKQ 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  712 EAVATLEKEHSAELERLcSSLEAKHREVVSSLQKKIQEAQQKEE--AQLQKCLGQVEHRVHQKSYHVAGYEHELSSLlRE 789
Cdd:TIGR04523  370 NEIEKLKKENQSYKQEI-KNLESQINDLESKIQNQEKLNQQKDEqiKKLQQEKELLEKEIERLKETIIKNNSEIKDL-TN 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  790 KRQEVEGEHERrLDKMKEEHQQVMAKAREQYEAEER--KQRAELLGHLTGELERLQRaHERELE------TVRQEQHK-R 860
Cdd:TIGR04523  448 QDSVKELIIKN-LDNTRESLETQLKVLSRSINKIKQnlEQKQKELKSKEKELKKLNE-EKKELEekvkdlTKKISSLKeK 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  861 LEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQE---------------ETARREKQQLL--------DVQRQV 917
Cdd:TIGR04523  526 IEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEknkeieelkqtqkslKKKQEEKQELIdqkekekkDLIKEI 605

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 2217281769  918 ALKSEEATATHQQLEEAQKEhthllqsNQQLREILDELQARKLKLESQV 966
Cdd:TIGR04523  606 EEKEKKISSLEKELEKAKKE-------NEKLSSIIKNIKSKKNKLKQEV 647

CHASE3

COG5278

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

536-951

6.20e-05

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 47.21 E-value: 6.20e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  536 EQLSEAALKAMEEAVAQVLEQD-----QRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEE 610
Cdd:COG5278    113 EALIDQWLAELEQVIALRRAGGleaalALVRSGEGKALMDEIRARLLLLALALAALLLAAAALLLLLLALAALLALAELL 192

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  611 ARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAA 690
Cdd:COG5278    193 LLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALALLLAALLLALLAALALAALLAAALLALAA 272

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  691 LNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKclgQVEHRVH 770
Cdd:COG5278    273 LLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAAALAALLALALATALAAAAA---ALALLAA 349

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  771 QKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHEREL 850
Cdd:COG5278    350 LLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAAAAEAAAAAAAAAAASAAEALELAEALA 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  851 ETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQ 930
Cdd:COG5278    430 EALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAAALAEAEAAAALAAAAALSLALALAALL 509

                          410       420
                   ....*....|....*....|.
gi 2217281769  931 LEEAQKEHTHLLQSNQQLREI 951
Cdd:COG5278    510 LAAAEAALAAALAAALASAEL 530

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

558-998

7.11e-05

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 47.48 E-value: 7.11e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  558 QRHLLESKQEKMQQLREKLCQEEEE--EILRLHQQKEQSLSSLRERLQKAIE--------------------------EE 609
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESElkELEKKHQQLCEEKNALQEQLQAETElcaeaeemrarlaarkqeleeilhelES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  610 EARMREEESQRLSWLRAQVQSSTQADEDQIrAEQEASLQKLREE---LESQQKAERASL----EQKNRQMLEQLKEEIEA 682
Cdd:pfam01576   83 RLEEEEERSQQLQNEKKKMQQHIQDLEEQL-DEEEAARQKLQLEkvtTEAKIKKLEEDIllleDQNSKLSKERKLLEERI 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  683 SEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSA--ELERLCSSLEAKH---REVVSSLQKKIQEAQ---QKE 754
Cdd:pfam01576  162 SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGrqELEKAKRKLEGEStdlQEQIAELQAQIAELRaqlAKK 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  755 EAQLQKCLGQVEHRVHQKSyHVAGYEHELSSLLREKRQEVEGEHERR-------------LDKMKEEHQQVMAKAREQYE 821
Cdd:pfam01576  242 EEELQAALARLEEETAQKN-NALKKIRELEAQISELQEDLESERAARnkaekqrrdlgeeLEALKTELEDTLDTTAAQQE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  822 AeeRKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLEldletrakdvKARLALlevqeE 901
Cdd:pfam01576  321 L--RSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLE----------KAKQAL-----E 383

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  902 TARREKQQLLDVQRQVALKSEEA-TATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHF 980
Cdd:pfam01576  384 SENAELQAELRTLQQAKQDSEHKrKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDV 463

                          490
                   ....*....|....*...
gi 2217281769  981 SSLEAEAQKKQHLLREVT 998
Cdd:pfam01576  464 SSLESQLQDTQELLQEET 481

FAM184

pfam15665

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

642-875

7.53e-05

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

Pssm-ID: 464788 [Multi-domain] Cd Length: 211 Bit Score: 45.42 E-value: 7.53e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  642 EQEASLQKLREelesQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAAlnaakeKALQQLREQLEGERKEAVATLEK-E 720
Cdd:pfam15665   11 EHEAEIQALKE----AHEEEIQQILAETREKILQYKSKIGEELDLKRRI------QTLEESLEQHERMKRQALTEFEQyK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  721 HSAELERLCssLEAKHREVVSSLQKKIQEAQQKEEAQLQKclgqvehrvhqksyhvagyehelsslLREKRQEVEGEHER 800
Cdd:pfam15665   81 RRVEERELK--AEAEHRQRVVELSREVEEAKRAFEEKLES--------------------------FEQLQAQFEQEKRK 132

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217281769  801 RLDKMKEEHQQVMAKAREQYEAEERKqraellghLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKL 875
Cdd:pfam15665  133 ALEELRAKHRQEIQELLTTQRAQSAS--------SLAEQEKLEELHKAELESLRKEVEDLRKEKKKLAEEYEQKL 199

PRK11637

AmiB activator; Provisional

541-753

8.60e-05

AmiB activator; Provisional

Pssm-ID: 236942 [Multi-domain] Cd Length: 428 Bit Score: 46.61 E-value: 8.60e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  541 AALKAMEEAVAQVLEQdqrhlLESKQEKMQQLrEKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMRE----- 615
Cdd:PRK11637    75 AQLKKQEEAISQASRK-----LRETQNTLNQL-NKQIDELNASIAKLEQQQAAQERLLAAQLDAAFRQGEHTGLQlilsg 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  616 EESQRLSWLRAQVQSSTQADEDQIraeqeASLQKLREELeSQQKAErasLEQKNRQMLEQLKEEIEASEKSEQA------ 689
Cdd:PRK11637   149 EESQRGERILAYFGYLNQARQETI-----AELKQTREEL-AAQKAE---LEEKQSQQKTLLYEQQAQQQKLEQArnerkk 219

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217281769  690 ---ALNAAKEKALQQLRE--QLEGERKEAVATLEKEHSAELERlcsslEAKHREVVsslQKKIQEAQQK 753
Cdd:PRK11637   220 tltGLESSLQKDQQQLSElrANESRLRDSIARAEREAKARAER-----EAREAARV---RDKQKQAKRK 280

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

699-1076

8.70e-05

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 47.02 E-value: 8.70e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  699 LQQLREQLEGERKEAVATLEKEHSAELERLCS--------------SLEAKHREVVSSLQ--KKIQEAQQKEEAQLQ--- 759
Cdd:pfam05483   50 LEQVANSGDCHYQEGLKDSDFENSEGLSRLYSklykeaekikkwkvSIEAELKQKENKLQenRKIIEAQRKAIQELQfen 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  760 -KCLGQVEHRVHQKSYHVA--GYEHELSSLLRE---------KRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQ 827
Cdd:pfam05483  130 eKVSLKLEEEIQENKDLIKenNATRHLCNLLKEtcarsaektKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENA 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  828 RAELLGHLTGELERLQRAhERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARR-- 905
Cdd:pfam05483  210 RLEMHFKLKEDHEKIQHL-EEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKEli 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  906 EKQQLL---------DVQRQVALKS--EE----ATATHQQL---EEAQKEHTHLLQSNQQLreILDELQARKLKLESQVD 967
Cdd:pfam05483  289 EKKDHLtkeledikmSLQRSMSTQKalEEdlqiATKTICQLteeKEAQMEELNKAKAAHSF--VVTEFEATTCSLEELLR 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  968 LLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNAsphfepDLHIEDLRKSLGTNQT--------KEVSSSLSQSKED 1039
Cdd:pfam05483  367 TEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNK------EVELEELKKILAEDEKlldekkqfEKIAEELKGKEQE 440

                          410       420       430
                   ....*....|....*....|....*....|....*..
gi 2217281769 1040 LYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMR 1076
Cdd:pfam05483  441 LIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLK 477

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

619-958

1.09e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 46.43 E-value: 1.09e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  619 QRLSWLRAQVQSSTQADEDQIRAEQEA-SLQKLREELESQ---QKAERASLEQKNRQMLEQLKEEIEASE--KSEQAALN 692
Cdd:pfam07888   42 ERAELLQAQEAANRQREKEKERYKRDReQWERQRRELESRvaeLKEELRQSREKHEELEEKYKELSASSEelSEEKDALL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  693 AAKEKALQQLREQLEGERKEAVATLEKEhsAELERLCSSLEAKHREVV------SSLQKKIQEAQQkEEAQLQKCLGQVE 766
Cdd:pfam07888  122 AQRAAHEARIRELEEDIKTLTQRVLERE--TELERMKERAKKAGAQRKeeeaerKQLQAKLQQTEE-ELRSLSKEFQELR 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  767 HRVHQKSYHVAGYEHELSSLlrekrQEVEGEHERRLDKMKEEHQQvMAKAREQYEAEERKqrAELLGHLTGELERLQRAH 846
Cdd:pfam07888  199 NSLAQRDTQVLQLQDTITTL-----TQKLTTAHRKEAENEALLEE-LRSLQERLNASERK--VEGLGEELSSMAAQRDRT 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  847 ERELETVRQEQHK---RLEDLRRRHRE------QERK--LQDLELDLETRAKDVKARLALLE-VQEETARREKQQL---- 910
Cdd:pfam07888  271 QAELHQARLQAAQltlQLADASLALREgrarwaQEREtlQQSAEADKDRIEKLSAELQRLEErLQEERMEREKLEVelgr 350

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 2217281769  911 -LDVQR-QVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQAR 958
Cdd:pfam07888  351 eKDCNRvQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQR 400

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

713-958

1.11e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 1.11e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  713 AVATLEKEHSAELERLCSSLEAKhrevvsslqKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLlrEKRQ 792
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAEL---------EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAAL--EAEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  793 EVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAheRELETVRQEQHKRLEDLRRrhreqe 872
Cdd:COG4942     86 AELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRL--QYLKYLAPARREQAEELRA------ 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  873 rKLQDLElDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEeatathQQLEEAQKEHTHLLQSNQQLREIL 952
Cdd:COG4942    158 -DLAELA-ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLE------KELAELAAELAELQQEAEELEALI 229


                   ....*.
gi 2217281769  953 DELQAR 958
Cdd:COG4942    230 ARLEAE 235

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

653-950

1.42e-04

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 46.25 E-value: 1.42e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  653 ELESQQKAERASLEQKNRQMlEQLKEEIEASEKSEQAALNAAKE---------KALQQLREQLEGERKEA---------- 713
Cdd:pfam05483  272 QLEEKTKLQDENLKELIEKK-DHLTKELEDIKMSLQRSMSTQKAleedlqiatKTICQLTEEKEAQMEELnkakaahsfv 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  714 -------VATLEKEHSAELERLCSSlEAKHREVVSSLQKKIQEAQQK---------EEAQLQKCLGQVEHRVHQK----- 772
Cdd:pfam05483  351 vtefeatTCSLEELLRTEQQRLEKN-EDQLKIITMELQKKSSELEEMtkfknnkevELEELKKILAEDEKLLDEKkqfek 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  773 -SYHVAGYEHELSSLLREKRQEVEG-EHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGH----LTGELERLQRAH 846
Cdd:pfam05483  430 iAEELKGKEQELIFLLQAREKEIHDlEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHcdklLLENKELTQEAS 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  847 ERELETVRQEQH------------KRLEDLRRRHREQERKLQDLELDLETRAKDVKARLallEVQEETARREKQQLLDVQ 914
Cdd:pfam05483  510 DMTLELKKHQEDiinckkqeermlKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKL---DKSEENARSIEYEVLKKE 586

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 2217281769  915 RQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLRE 950
Cdd:pfam05483  587 KQMKILENKCNNLKKQIENKNKNIEELHQENKALKK 622

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

810-939

1.52e-04

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 46.36 E-value: 1.52e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  810 QQVMAKAREQYEAEERK-----QRAEllghltgELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLEt 884
Cdd:PRK00409   501 ENIIEEAKKLIGEDKEKlneliASLE-------ELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAE- 572

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217281769  885 rakdVKARLALLEVQEETARREKQ-QLLDVQRQVALKSEEATATHQQLEEAQKEHT 939
Cdd:PRK00409   573 ----KEAQQAIKEAKKEADEIIKElRQLQKGGYASVKAHELIEARKRLNKANEKKE 624

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

788-960

1.87e-04

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 45.29 E-value: 1.87e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  788 REKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRR 867
Cdd:pfam13868   31 KKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVERI 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  868 HREQERKLQDLELD----LETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHT---- 939
Cdd:pfam13868  111 QEEDQAEAEEKLEKqrqlREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEEREAEREEIEEEKEREIarlr 190

                          170       180
                   ....*....|....*....|.
gi 2217281769  940 HLLQSNQQLREILDELQARKL 960
Cdd:pfam13868  191 AQQEKAQDEKAERDELRAKLY 211

AtpF

COG0711

FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]; FoF1-type ...

633-705

2.15e-04

FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit b or b' is part of the Pathway/BioSystem: FoF1-type ATP synthase

Pssm-ID: 440475 [Multi-domain] Cd Length: 152 Bit Score: 43.24 E-value: 2.15e-04

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217281769  633 QADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQ 705
Cdd:COG0711     47 KEEAEAALAEYEEKLAEARAEAAEIIAEARKEAEAIAEEAKAEAEAEAERIIAQAEAEIEQERAKALAELRAE 119

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

812-965

2.35e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.15 E-value: 2.35e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  812 VMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRqeqhKRLEDLRRRHREQERKLQDLELDLET---RAKD 888
Cdd:COG1579      2 MPEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALE----ARLEAAKTELEDLEKEIKRLELEIEEveaRIKK 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  889 VKARLAL---------LEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEH-THLLQSNQQLREILDELQAR 958
Cdd:COG1579     78 YEEQLGNvrnnkeyeaLQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELeAELEEKKAELDEELAELEAE 157


                   ....*..
gi 2217281769  959 KLKLESQ 965
Cdd:COG1579    158 LEELEAE 164

DUF4670

pfam15709

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

630-830

2.61e-04

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 45.33 E-value: 2.61e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  630 SSTQADEDQIRAEQeASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE 709
Cdd:pfam15709  329 EQEKASRDRLRAER-AEMRRLEVERKRREQEEQRRLQQEQLERAEKMREELELEQQRRFEEIRLRKQRLEEERQRQEEEE 407

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  710 RKEAVatlekEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgqvehrvhqksyhvagyehelssllRE 789
Cdd:pfam15709  408 RKQRL-----QLQAAQERARQQQEEFRRKLQELQRKKQQEEAERAEAEKQ----------------------------RQ 454

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2217281769  790 KRQEVE-GEHERRLDKMKEEH------QQVMAKAREQYEAEERKQRAE 830
Cdd:pfam15709  455 KELEMQlAEEQKRLMEMAEEErleyqrQKQEAEEKARLEAEERRQKEE 502

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

636-908

2.69e-04

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 45.52 E-value: 2.69e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  636 EDQIRAEQEASLQKLREELESQQKAERASLEQKN-------RQMLEQLKEEIEASEKSEQAALNAAK-----EKALQQLR 703
Cdd:pfam09731  181 TDSALQKAEALAEKLKEVINLAKQSEEEAAPPLLdaapetpPKLPEHLDNVEEKVEKAQSLAKLVDQykelvASERIVFQ 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  704 EQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVvSSLQKKIQEAQQKEEAQLQKCLGQVEHrvhqksyhvagyehEL 783
Cdd:pfam09731  261 QELVSIFPDIIPVLKEDNLLSNDDLNSLIAHAHREI-DQLSKKLAELKKREEKHIERALEKQKE--------------EL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  784 SSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEerkqraellghLTGELERLQRAHERELETVRQEQHkrlED 863
Cdd:pfam09731  326 DKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEK-----------LRTELERQAEAHEEHLKDVLVEQE---IE 391

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2217281769  864 LRRRHR-------EQERKLQDLELD-LETRAKDVKARLALLEVQEETARREKQ 908
Cdd:pfam09731  392 LQREFLqdikekvEEERAGRLLKLNeLLANLKGLEKATSSHSEVEDENRKAQQ 444

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

639-866

3.10e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.14 E-value: 3.10e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  639 IRAEQEASLQKLREELESQQKAERasleQKNRQMLEQLKEEIEASEKSEQAalNAAKEKALQQLREQLEGERKEavatlE 718
Cdd:COG4717     43 IRAMLLERLEKEADELFKPQGRKP----ELNLKELKELEEELKEAEEKEEE--YAELQEELEELEEELEELEAE-----L 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  719 KEHSAELERLcssleakhrEVVSSLQKKIQEAQQKEE--AQLQKCLGQVEHRVHQksyhVAGYEHELSSlLREKRQEVEG 796
Cdd:COG4717    112 EELREELEKL---------EKLLQLLPLYQELEALEAelAELPERLEELEERLEE----LRELEEELEE-LEAELAELQE 177

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217281769  797 EHERRLDKMKEEHQQVMAKAREQYEA--EERKQRAELLGHLTGELERLQRAHER-ELETVRQEQHKRLEDLRR 866
Cdd:COG4717    178 ELEELLEQLSLATEEELQDLAEELEElqQRLAELEEELEEAQEELEELEEELEQlENELEAAALEERLKEARL 250

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

492-727

3.18e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 45.33 E-value: 3.18e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  492 EEPPQGPEGQPEWKEAEELGEDSAASLSLQLSlQRRSTEPVAPPEQlsEAALKAMEEAVAQVleqdqrhlleSKQEKMQQ 571
Cdd:COG3096    430 GLPDLTPENAEDYLAAFRAKEQQATEEVLELE-QKLSVADAARRQF--EKAYELVCKIAGEV----------ERSQAWQT 496

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  572 LREKLCQeeeeeiLRLHQQKEQSLSSLRERLQKAieeeearmreeeSQRLswlRAQVQSSTQADEDQIRAEQEASLQKLR 651
Cdd:COG3096    497 ARELLRR------YRSQQALAQRLQQLRAQLAEL------------EQRL---RQQQNAERLLEEFCQRIGQQLDAAEEL 555

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  652 EELESQQKAERASLEQKN----------RQMLEQLKEEIEASEKSEQAALNAAkeKALQQLREQLEGERKEAVA------ 715
Cdd:COG3096    556 EELLAELEAQLEELEEQAaeaveqrselRQQLEQLRARIKELAARAPAWLAAQ--DALERLREQSGEALADSQEvtaamq 633

                          250
                   ....*....|...
gi 2217281769  716 -TLEKEHSAELER 727
Cdd:COG3096    634 qLLEREREATVER 646

EzrA

pfam06160

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...

627-959

3.29e-04

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.

Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 44.84 E-value: 3.29e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  627 QVQSSTQADEDQIRAEQEASLQKLREELESqqkaeraslEQKNRQMLEQLKEEIEASEKsEQAALNAAKEKALQQLREQL 706
Cdd:pfam06160   86 KALDEIEELLDDIEEDIKQILEELDELLES---------EEKNREEVEELKDKYRELRK-TLLANRFSYGPAIDELEKQL 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  707 EgerkeavaTLEKEHSaELERLCSS---LEAkhREVVSSLQKKIQEAQQKEE------AQLQKCL-GQVEhrvhqksyhv 776
Cdd:pfam06160  156 A--------EIEEEFS-QFEELTESgdyLEA--REVLEKLEEETDALEELMEdipplyEELKTELpDQLE---------- 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  777 agyehELSSLLRE-KRQEVEGEH---ERRLDKMKEEHQQVMAkareQYEAEERKQRAELLGHLTGELERLQRAHERELET 852
Cdd:pfam06160  215 -----ELKEGYREmEEEGYALEHlnvDKEIQQLEEQLEENLA----LLENLELDEAEEALEEIEERIDQLYDLLEKEVDA 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  853 vRQEQHKRLEDLRRRHREQERKLQDLELDLETrakdVKARLALLEVQEETARREKQQLLDVQRQVAL---KSEEATATH- 928
Cdd:pfam06160  286 -KKYVEKNLPEIEDYLEHAEEQNKELKEELER----VQQSYTLNENELERVRGLEKQLEELEKRYDEiveRLEEKEVAYs 360

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 2217281769  929 ----------QQLEEAQKEHTHLLQSNQQLREilDELQARK 959
Cdd:pfam06160  361 elqeeleeilEQLEEIEEEQEEFKESLQSLRK--DELEARE 399

COG4995

Uncharacterized conserved protein, contains CHAT domain [Function unknown];

549-984

3.88e-04

Uncharacterized conserved protein, contains CHAT domain [Function unknown];

Pssm-ID: 444019 [Multi-domain] Cd Length: 711 Bit Score: 44.96 E-value: 3.88e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  549 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQV 628
Cdd:COG4995     12 ALLAALALALLALALLLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALALAALALALLA 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  629 QSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAkEKALQQLREQLEG 708
Cdd:COG4995     92 AALALALAAAALAALALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAA-AAAAAAALLALAL 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  709 ERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR 788
Cdd:COG4995    171 ALAAAALALLALLLAALAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALLALAAAAAAL 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  789 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRH 868
Cdd:COG4995    251 AAAAAALLALAAALLLLAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALALLLLAALLLLLAAL 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  869 REQERKLQDLELDLETRAkdvkARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQL 948
Cdd:COG4995    331 ALLALLLLLAAAALLAAA----LAAALALAAALALALLAALLLLLAALLALLLEALLLLLLALLAALLLLAAALLALAAA 406

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 2217281769  949 REILDELQARKLKLESQVDLLQAQSQQLQKHFSSLE 984
Cdd:COG4995    407 QLLRLLLAALALLLALAAYAAARLALLALIEYIILP 442

PTZ00121

MAEBL; Provisional

341-760

4.99e-04

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 44.75 E-value: 4.99e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  341 KASEKEAPEDTVDAGEEGSRREEAAK--EPKKKASALEEGSSDA---SQELEISEHMKEPQLSDSIASDPKSFHGLDFGF 415
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKkaEEAKKADEAKKKAEEAkkkADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  416 RSRISEHLLDVDvlspvlggACRQAQQplgIEDKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQSPPRslATEEEPP 495
Cdd:PTZ00121  1532 EAKKADEAKKAE--------EKKKADE---LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE--ARIEEVM 1598

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  496 QGPEGQPEWKEAEELGEDSAASLSLQLslqRRSTEPVAPPEQLSEAALKAMEEAvAQVLEQDQRHLLESKQEKMQQLREK 575
Cdd:PTZ00121  1599 KLYEEEKKMKAEEAKKAEEAKIKAEEL---KKAEEEKKKVEQLKKKEAEEKKKA-EELKKAEEENKIKAAEEAKKAEEDK 1674

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  576 LCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEesqrlswlRAQVQSSTQADEDQIRAEQEAslqklREELE 655
Cdd:PTZ00121  1675 KKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK--------KKAEELKKAEEENKIKAEEAK-----KEAEE 1741

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  656 SQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQ--LREQLEGERK--------EAVATLEKEHSAEL 725
Cdd:PTZ00121  1742 DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEedEKRRMEVDKKikdifdnfANIIEGGKEGNLVI 1821

                          410       420       430
                   ....*....|....*....|....*....|....*
gi 2217281769  726 ERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK 760
Cdd:PTZ00121  1822 NDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNK 1856

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

619-989

5.09e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 44.72 E-value: 5.09e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  619 QRLSWLRAQVQSSTQADEDQiraeQEASLQKLREELE--SQQKAERASLEQKNRQMLEQL---KEEIEASEK--SEQAAL 691
Cdd:pfam15921  429 QRLEALLKAMKSECQGQMER----QMAAIQGKNESLEkvSSLTAQLESTKEMLRKVVEELtakKMTLESSERtvSDLTAS 504

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  692 NAAKEKALQQLREQLEGERKEAVATL--------EKEHSAELERLCSSLE---AKHREVVSSLQKKIQE----------- 749
Cdd:pfam15921  505 LQEKERAIEATNAEITKLRSRVDLKLqelqhlknEGDHLRNVQTECEALKlqmAEKDKVIEILRQQIENmtqlvgqhgrt 584

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  750 --AQQKEEAQLQKCLGqvEHRVHQKSYHVagyehelsslLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEA--EER 825
Cdd:pfam15921  585 agAMQVEKAQLEKEIN--DRRLELQEFKI----------LKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAvkDIK 652

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  826 KQRAELLGHLtgelerlqRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARR 905
Cdd:pfam15921  653 QERDQLLNEV--------KTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGH 724

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  906 EKQQLLDVQRQVALKSEEATATH---QQLEE----AQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQK 978
Cdd:pfam15921  725 AMKVAMGMQKQITAKRGQIDALQskiQFLEEamtnANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKE 804

                          410
                   ....*....|.
gi 2217281769  979 HFSSLEAEAQK 989
Cdd:pfam15921  805 KVANMEVALDK 815

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

536-855

5.30e-04

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 44.66 E-value: 5.30e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  536 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAieEEEARMRE 615
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA--EEELAEAE 781

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  616 EESQRLSWLRAQVQSSTQADEDQIRAEQEA------SLQKLREELESQQKAERAS------LEQKNRQMLEQLkEEIEAS 683
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAEltllneEAANLRERLESLERRIAATerrledLEEQIEELSEDI-ESLAAE 860

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  684 EKSEQAALNAAKE--KALQQLREQLEGERKEAVATLEK------EHSAELERLCSSLEAKhREVVSSLQKKIQEAQQKEE 755
Cdd:TIGR02168  861 IEELEELIEELESelEALLNERASLEEALALLRSELEElseelrELESKRSELRRELEEL-REKLAQLELRLEGLEVRID 939

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  756 AQLQKC--LGQVEHRVHQKSYhvagyehelssllrEKRQEVEGEHERRLDKMKEEHQQ---VMAKAREQYEAEErkqraE 830
Cdd:TIGR02168  940 NLQERLseEYSLTLEEAEALE--------------NKIEDDEEEARRRLKRLENKIKElgpVNLAAIEEYEELK-----E 1000

                          330       340
                   ....*....|....*....|....*
gi 2217281769  831 LLGHLTGELERLQRAHERELETVRQ 855
Cdd:TIGR02168 1001 RYDFLTAQKEDLTEAKETLEEAIEE 1025

GumC

COG3206

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

654-935

5.46e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.62 E-value: 5.46e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  654 LESQQKAERASLEQKNRQMLEQLKEeieASEKSEQAalnaakEKALQQLREQlegerkEAVATLEKEHSAELERLcSSLE 733
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPE---LRKELEEA------EAALEEFRQK------NGLVDLSEEAKLLLQQL-SELE 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  734 AKHREvvssLQKKIQEAQQKEEaQLQKCLGQVEHRVHQKSyhvagyEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVM 813
Cdd:COG3206    226 SQLAE----ARAELAEAEARLA-ALRAQLGSGPDALPELL------QSPVIQQLRAQLAELEAELAELSARYTPNHPDVI 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  814 AKareqyeaeeRKQRAELLGHLTGELERLQRAHERELETVRQeqhkRLEDLRRRHREQERKLQDLeldletrakdvkarl 893
Cdd:COG3206    295 AL---------RAQIAALRAQLQQEAQRILASLEAELEALQA----REASLQAQLAQLEARLAEL--------------- 346

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2217281769  894 allevqeetaRREKQQLLDVQRQVALKSEEATATHQQLEEAQ 935
Cdd:COG3206    347 ----------PELEAELRRLEREVEVARELYESLLQRLEEAR 378

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

783-937

6.32e-04

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 44.09 E-value: 6.32e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  783 LSSLLREKRQEV-EGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRaellghltgELERLQRAH-ERELETVRQEQHKR 860
Cdd:COG2268    186 LDALGRRKIAEIiRDARIAEAEAERETEIAIAQANREAEEAELEQER---------EIETARIAEaEAELAKKKAEERRE 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  861 LEDLRRR-----HREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLL--DVQRQVALKSEEATATHQQlEE 933
Cdd:COG2268    257 AETARAEaeaayEIAEANAEREVQRQLEIAEREREIELQEKEAEREEAELEADVRKpaEAEKQAAEAEAEAEAEAIR-AK 335


                   ....
gi 2217281769  934 AQKE 937
Cdd:COG2268    336 GLAE 339

PspA

COG1842

Phage shock protein A [Transcription, Signal transduction mechanisms];

637-756

7.23e-04

Phage shock protein A [Transcription, Signal transduction mechanisms];

Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 42.50 E-value: 7.23e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  637 DQIRAEQEASLQKLREELeSQQKAERASLEQKnrqmLEQLKEEIEASEKSEQAALNAAKE----KALQQlREQLEGERKE 712
Cdd:COG1842     29 DQAIRDMEEDLVEARQAL-AQVIANQKRLERQ----LEELEAEAEKWEEKARLALEKGREdlarEALER-KAELEAQAEA 102

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2217281769  713 AVATLEkEHSAELERLcssleakhREVVSSLQKKIQEAQQKEEA 756
Cdd:COG1842    103 LEAQLA-QLEEQVEKL--------KEALRQLESKLEELKAKKDT 137

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

743-914

8.85e-04

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 42.95 E-value: 8.85e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  743 LQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAG----YEHELSSLLRE-------------------KRQEVEGEHE 799
Cdd:cd16269    107 CKQNEEASSKRCQALLQELSAPLEEKISQGSYSVPGgyqlYLEDREKLVEKyrqvprkgvkaeevlqeflQSKEAEAEAI 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  800 RRLDKMKEEHQQVMAKAREQYEAEErkQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLE 879
Cdd:cd16269    187 LQADQALTEKEKEIEAERAKAEAAE--QERKLLEEQQRELEQKLEDQERSYEEHLRQLKEKMEEERENLLKEQERALESK 264

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2217281769  880 LDLETRakdvkarlALLEVQEETARREKQQLLDVQ 914
Cdd:cd16269    265 LKEQEA--------LLEEGFKEQAELLQEEIRSLK 291

HCR

pfam07111

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...

653-959

9.20e-04

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.

Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 43.59 E-value: 9.20e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  653 ELESQQKAERASLEQKNRQMLEqLKEEIeASEKSEQAALnaakEKALQQLREQLEGERKEAVA-TLEKEHSAELERL--- 728
Cdd:pfam07111  321 QLKAQDLEHRDSVKQLRGQVAE-LQEQV-TSQSQEQAIL----QRALQDKAAEVEVERMSAKGlQMELSRAQEARRRqqq 394

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  729 -CSSLEAKHREVVSSLqKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYeHELSSLLREK------RQE-------- 793
Cdd:pfam07111  395 qTASAEEQLKFVVNAM-SSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKV-HTIKGLMARKvalaqlRQEscpppppa 472

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  794 --VEGEHERRLDKMKEEH--------------QQVMAKAREQYEAEeRKQRAELLGHLTGELERLQRAHE---RELETVR 854
Cdd:pfam07111  473 ppVDADLSLELEQLREERnrldaelqlsahliQQEVGRAREQGEAE-RQQLSEVAQQLEQELQRAQESLAsvgQQLEVAR 551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  855 QEQHKRLED---LRRRHREQE----RKLQDLELDLETRAKDvkaRLALLEVQEETARREKQQLLDVQRQVALKSEEATAT 927
Cdd:pfam07111  552 QGQQESTEEaasLRQELTQQQeiygQALQEKVAEVETRLRE---QLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKER 628

                          330       340       350
                   ....*....|....*....|....*....|..
gi 2217281769  928 HQQLEEAQKEHTHllQSNQQLREILDELQARK 959
Cdd:pfam07111  629 NQELRRLQDEARK--EEGQRLARRVQELERDK 658

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

823-1049

1.06e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.97 E-value: 1.06e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  823 EERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEET 902
Cdd:COG4372      9 GKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQ 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  903 ARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSS 982
Cdd:COG4372     89 LQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAA 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217281769  983 LEAEAQ-----KKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHN 1049
Cdd:COG4372    169 LEQELQalseaEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLD 240

mukB

chromosome partition protein MukB;

557-996

1.12e-03

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.79 E-value: 1.12e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  557 DQRHLLESKQEKMQQLREklcqeeeeeiLRLHQQKEQSLSSLRERLQKaieeeearmreeesqrlswlRAQVQSSTQADE 636
Cdd:PRK04863   507 EQRHLAEQLQQLRMRLSE----------LEQRLRQQQRAERLLAEFCK--------------------RLGKNLDDEDEL 556

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  637 DQIRAEQEASLQKLREELESQqkAERASLEqknRQMLEQLKEEIEASEKSEQAALNAakEKALQQLREQLEGERKEAVA- 715
Cdd:PRK04863   557 EQLQEELEARLESLSESVSEA--RERRMAL---RQQLEQLQARIQRLAARAPAWLAA--QDALARLREQSGEEFEDSQDv 629

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  716 ------TLEKEHSAELERlcSSLEAKHRevvsSLQKKIQEAQQKEEAQLQKCLGQVEH-------------RVHQKSYHV 776
Cdd:PRK04863   630 teymqqLLERERELTVER--DELAARKQ----ALDEEIERLSQPGGSEDPRLNALAERfggvllseiyddvSLEDAPYFS 703

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  777 AGY--------------------------------EHELSSLlREKRQEVE----------GEHERRLDKMKEeHQQVMA 814
Cdd:PRK04863   704 ALYgparhaivvpdlsdaaeqlagledcpedlyliEGDPDSF-DDSVFSVEelekavvvkiADRQWRYSRFPE-VPLFGR 781

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  815 KAREQYEAE---ERKQRAELLGHLTGELERLQRAHERELETVRQ--------EQHKRLEDLRRRHREQERKLQDLE---L 880
Cdd:PRK04863   782 AAREKRIEQlraEREELAERYATLSFDVQKLQRLHQAFSRFIGShlavafeaDPEAELRQLNRRRVELERALADHEsqeQ 861

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  881 DLETRAKDVKARLALL--------------------EVQEETARRE---------------------------------- 906
Cdd:PRK04863   862 QQRSQLEQAKEGLSALnrllprlnlladetladrveEIREQLDEAEeakrfvqqhgnalaqlepivsvlqsdpeqfeqlk 941

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  907 ------KQQLLDVQRQV-ALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKH 979
Cdd:PRK04863   942 qdyqqaQQTQRDAKQQAfALTEVVQRRAHFSYEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQV 1021

                          570
                   ....*....|....*..
gi 2217281769  980 FSSLEAEAQKKQHLLRE 996
Cdd:PRK04863  1022 LASLKSSYDAKRQMLQE 1038

CHASE3

COG5278

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

640-1036

1.36e-03

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 42.97 E-value: 1.36e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  640 RAEQEASLQKLREEL--ESQQKAERASLEQKNRQMLEQLKEEIEAS-EKSEQAALNAAKEKALQQLREQLEGERKEAVAT 716
Cdd:COG5278     85 RAEIDELLAELRSLTadNPEQQARLDELEALIDQWLAELEQVIALRrAGGLEAALALVRSGEGKALMDEIRARLLLLALA 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  717 LEKEHSAELERLcsSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEG 796
Cdd:COG5278    165 LAALLLAAAALL--LLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALAL 242

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  797 EHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQ 876
Cdd:COG5278    243 ALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAA 322

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  877 DLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQ 956
Cdd:COG5278    323 AALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAA 402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  957 ARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQS 1036
Cdd:COG5278    403 AAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAA 482

Caldesmon

pfam02029

Caldesmon;

634-909

1.37e-03

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 42.93 E-value: 1.37e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  634 ADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALN---AAKEKALQQLREQLEGER 710
Cdd:pfam02029    8 ARERRRRAREERRRQKEEEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEEAFLDrtaKREERRQKRLQEALERQK 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  711 KEAVATLEKEHSAELERL------CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELS 784
Cdd:pfam02029   88 EFDPTIADEKESVAERKEnneeeeNSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEEEGEEEEDKSEEAE 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  785 SLLRE--KRQEVEGEHERRLDKMKEEHQQVMAkaREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQH---- 858
Cdd:pfam02029  168 EVPTEnfAKEEVKDEKIKKEKKVKYESKVFLD--QKRGHPEVKSQNGEEEVTKLKVTTKRRQGGLSQSQEREEEAEvfle 245

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217281769  859 --KRLEDLRRRHREQER--------KLQDLELDLETRAKDVKARLALLEVQEETARREKQQ 909
Cdd:pfam02029  246 aeQKLEELRRRRQEKESeefeklrqKQQEAELELEELKKKREERRKLLEEEEQRRKQEEAE 306

PRK12704

phosphodiesterase; Provisional

730-910

1.52e-03

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.84 E-value: 1.52e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  730 SSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHqksyhvagyehelssllrEKRQEVEGEHERRLDKMKEEH 809
Cdd:PRK12704    27 KIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIH------------------KLRNEFEKELRERRNELQKLE 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  810 QQVMAKareqyeaEER-KQRAELLGHLTGELErlqrAHERELETVRQEQHKRLEDLRRRHREQERKLQDL-ELDLEtrak 887
Cdd:PRK12704    89 KRLLQK-------EENlDRKLELLEKREEELE----KKEKELEQKQQELEKKEEELEELIEEQLQELERIsGLTAE---- 153

                          170       180
                   ....*....|....*....|...
gi 2217281769  888 dvKARLALLEVQEETARREKQQL 910
Cdd:PRK12704   154 --EAKEILLEKVEEEARHEAAVL 174

GumC

COG3206

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

783-964

1.64e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.08 E-value: 1.64e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  783 LSSLLREKRQEVEgEHERRLDKMKEEHQQVMAKAREQYEAEE----RKQRAELLGHLTgELERLQRAHERELETVRQE-- 856
Cdd:COG3206    180 LEEQLPELRKELE-EAEAALEEFRQKNGLVDLSEEAKLLLQQlselESQLAEARAELA-EAEARLAALRAQLGSGPDAlp 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  857 ---QHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLL-DVQRQVALKSEEATATHQQLE 932
Cdd:COG3206    258 ellQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILaSLEAELEALQAREASLQAQLA 337

                          170       180       190
                   ....*....|....*....|....*....|..
gi 2217281769  933 EAQKEHTHLLQSNQQLREILDELQARKLKLES 964
Cdd:COG3206    338 QLEARLAELPELEAELRRLEREVEVARELYES 369

HlpA

COG2825

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ...

648-750

1.65e-03

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 442073 [Multi-domain] Cd Length: 171 Bit Score: 40.97 E-value: 1.65e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  648 QKLREELESQQKAERASLEQKNRQmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAvatlEKEhsaeler 727
Cdd:COG2825     42 KAAQKKLEKEFKKRQAELQKLEKE-LQALQEKLQKEAATLSEEERQKKERELQKKQQELQRKQQEA----QQD------- 109

                           90       100
                   ....*....|....*....|...
gi 2217281769  728 lcssLEAKHREVVSSLQKKIQEA 750
Cdd:COG2825    110 ----LQKRQQELLQPILEKIQKA 128

dnaK

PRK00290

molecular chaperone DnaK; Provisional

628-757

1.68e-03

molecular chaperone DnaK; Provisional

Pssm-ID: 234715 [Multi-domain] Cd Length: 627 Bit Score: 42.78 E-value: 1.68e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  628 VQSSTQADEDQI-RAEQEASL-----QKLREELESQQKAEraSLEQKNRQMLEQLKEEIEASEKSEQaalnaakEKALQQ 701
Cdd:PRK00290   494 ITASSGLSDEEIeRMVKDAEAnaeedKKRKELVEARNQAD--SLIYQTEKTLKELGDKVPADEKEKI-------EAAIKE 564

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217281769  702 LREQLEGERKEAVatleKEHSAELErlcssleakhrEVVSSLQKKIQEAQQKEEAQ 757
Cdd:PRK00290   565 LKEALKGEDKEAI----KAKTEELT-----------QASQKLGEAMYQQAQAAQGA 605

Ax_dynein_light

pfam10211

Axonemal dynein light chain; Axonemal dynein light chain proteins play a dynamic role in ...

637-708

1.70e-03

Axonemal dynein light chain; Axonemal dynein light chain proteins play a dynamic role in flagellar and cilia motility. Eukaryotic cilia and flagella are complex organelles consisting of a core structure, the axoneme, which is composed of nine microtubule doublets forming a cylinder that surrounds a pair of central singlet microtubules. This ultra-structural arrangement seems to be one of the most stable micro-tubular assemblies known and is responsible for the flagellar and ciliary movement of a large number of organizms ranging from protozoan to mammals. This light chain interacts directly with the N-terminal half of the heavy chains.

Pssm-ID: 463000 [Multi-domain] Cd Length: 187 Bit Score: 41.02 E-value: 1.70e-03

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217281769  637 DQIRAEQEASLQKLREELESQQKaERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKeKALQQLREQLEG 708
Cdd:pfam10211  118 EQGKAELEKKIADLEEEKEELEK-QVAELKAKCEAIEKREEERRQAEEKKHAEEIAFLK-KTNQQLKAQLER 187

mukB

chromosome partition protein MukB;

624-967

1.73e-03

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.02 E-value: 1.73e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  624 LRAQVQSStqadEDQIRAEQEAsLQKLREELEsQQKAERASLEQKNRQMLEQLKEEIEA---SEKSEQAalnaakEKALQ 700
Cdd:PRK04863   291 LRRELYTS----RRQLAAEQYR-LVEMARELA-ELNEAESDLEQDYQAASDHLNLVQTAlrqQEKIERY------QADLE 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  701 QLREQLEgERKEAVAtLEKEHSAELERLCSSLEakhrEVVSSLQKKIQEAQQKEEAQlQKCLGQVEHRVH-----QKSYH 775
Cdd:PRK04863   359 ELEERLE-EQNEVVE-EADEQQEENEARAEAAE----EEVDELKSQLADYQQALDVQ-QTRAIQYQQAVQaleraKQLCG 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  776 VAGYEHE-LSSLLREKRQEVEGEHERRLDKmkeEHQQVMAK-AREQYEaeerkQRAELLGHLTGELERlQRAHERELETV 853
Cdd:PRK04863   432 LPDLTADnAEDWLEEFQAKEQEATEELLSL---EQKLSVAQaAHSQFE-----QAYQLVRKIAGEVSR-SEAWDVARELL 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  854 RQ-EQHK----RLEDLRRRHREQERKLQdLELDLETRAKDVKARLAL-----LEVQEETARREkQQLLDVQRQVALKSEE 923
Cdd:PRK04863   503 RRlREQRhlaeQLQQLRMRLSELEQRLR-QQQRAERLLAEFCKRLGKnlddeDELEQLQEELE-ARLESLSESVSEARER 580

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 2217281769  924 ATATHQQLEEaqkehthllqsnqqlreildelqarklkLESQVD 967
Cdd:PRK04863   581 RMALRQQLEQ----------------------------LQARIQ 596

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

782-910

1.83e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.45 E-value: 1.83e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  782 ELSSLLREKRQEVEgEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHErELETVRQEQHKRL 861
Cdd:COG1579     42 ALEARLEAAKTELE-DLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQKEIESLKRRIS-DLEDEILELMERI 119

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 2217281769  862 EDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQL 910
Cdd:COG1579    120 EELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168

PRK11091

aerobic respiration control sensor protein ArcB; Provisional

848-921

2.16e-03

aerobic respiration control sensor protein ArcB; Provisional

Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 42.62 E-value: 2.16e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  848 RELETVRQEQHK---RLEDLRRRHREQERKLQD----LELDLETRAKDVKARLALL-EVQEETARREKQQLLDVQRQVAL 919
Cdd:PRK11091    78 EQLEESRQRLSRlvaKLEEMRERDLELNVQLKDniaqLNQEIAEREKAEEARQEAFeQLKNEIKEREETQIELEQQSSLL 157


                   ..
gi 2217281769  920 KS 921
Cdd:PRK11091   158 RS 159

ClpA

COG0542

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...

663-756

2.38e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 42.38 E-value: 2.38e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  663 ASLEQKNRQmLEQLKEEIEASEKsEQAALNAAKEKALQQLREQLEGERKEAVA--TLEKEHSAELERLCSSLEAKHrEVV 740
Cdd:COG0542    411 EELDELERR-LEQLEIEKEALKK-EQDEASFERLAELRDELAELEEELEALKArwEAEKELIEEIQELKEELEQRY-GKI 487

                           90
                   ....*....|....*.
gi 2217281769  741 SSLQKKIQEAQQKEEA 756
Cdd:COG0542    488 PELEKELAELEEELAE 503

GumC

COG3206

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

839-1003

2.48e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.31 E-value: 2.48e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  839 LERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLE-----LDLETRAKDVKARLALLEVQEETARRE------- 906
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRqknglVDLSEEAKLLLQQLSELESQLAEARAElaeaear 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  907 ---------------------------KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQS-NQQLREILDELQAR 958
Cdd:COG3206    242 laalraqlgsgpdalpellqspviqqlRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQlQQEAQRILASLEAE 321

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2217281769  959 KLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENN 1003
Cdd:COG3206    322 LEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVAREL 366

Filament

pfam00038

Intermediate filament protein;

637-925

2.65e-03

Intermediate filament protein;

Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 41.44 E-value: 2.65e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  637 DQIRA--EQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKsEQAALNAAKEKA---LQQLREQLE---G 708
Cdd:pfam00038   18 DKVRFleQQNKLLETKISELRQKKGAEPSRLYSLYEKEIEDLRRQLDTLTV-ERARLQLELDNLrlaAEDFRQKYEdelN 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  709 ERKEA---VATLEKE-HSAELERLcssleakhrevvsSLQKKIQEAQqkEEAQLQKCLGQVEHRvhqksyhvagyehELS 784
Cdd:pfam00038   97 LRTSAendLVGLRKDlDEATLARV-------------DLEAKIESLK--EELAFLKKNHEEEVR-------------ELQ 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  785 SLLREKRQEVEGEHERRLDKmkeehQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKrLEDL 864
Cdd:pfam00038  149 AQVSDTQVNVEMDAARKLDL-----TSALAEIRAQYEEIAAKNREEAEEWYQSKLEELQQAAARNGDALRSAKEE-ITEL 222

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  865 RRR----------HREQ----ERKLQDLELDLETRAKDVKARLALLEVQ-----EETAR--REKQQLLDVqrQVALKSEE 923
Cdd:pfam00038  223 RRTiqsleielqsLKKQkaslERQLAETEERYELQLADYQELISELEAElqetrQEMARqlREYQELLNV--KLALDIEI 300


                   ..
gi 2217281769  924 AT 925
Cdd:pfam00038  301 AT 302

PRK12705

hypothetical protein; Provisional

779-937

2.84e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.00 E-value: 2.84e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  779 YEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEllghLTGELERLQRAHEreletVRQEQH 858
Cdd:PRK12705    27 KRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREE----LQREEERLVQKEE-----QLDARA 97

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217281769  859 KRLEDLRRRHREQERKLQDLELDLETRAKDVKARlaLLEVQEETARREKQQLLDvQRQVALKSEEATATHQQLEEAQKE 937
Cdd:PRK12705    98 EKLDNLENQLEEREKALSARELELEELEKQLDNE--LYRVAGLTPEQARKLLLK-LLDAELEEEKAQRVKKIEEEADLE 173

OmpH

smart00935

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

648-753

3.21e-03

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 39.49 E-value: 3.21e-03

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769   648 QKLREELESQQKAERASLEQKNRQmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKehsaeler 727
Cdd:smart00935   17 KAAQKQLEKEFKKRQAELEKLEKE-LQKLKEKLQKDAATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQK-------- 87

                            90       100
                    ....*....|....*....|....*.
gi 2217281769   728 lcssleaKHREVVSSLQKKIQEAQQK 753
Cdd:smart00935   88 -------RQQEELQKILDKINKAIKE 106

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

554-1158

3.35e-03

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.88 E-value: 3.35e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  554 LEQDQRHLLESKQEKMQQLREKLCQEEEEEILRL-HQQKEQSLSSLRERLQKA-IEEEEARMREEESQRLSWLRAQVQSS 631
Cdd:pfam02463  234 LNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLaQVLKENKEEEKEKKLQEEeLKLLAKEEEELKSELLKLERRKVDDE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  632 TQADEDQIRAEQEASLQKLREELESQQKAERASLEqknRQMLEQLKEEIEASEKSEQAALNAAKEKALQQL-REQLEGER 710
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELE---IKREAEEEEEEELEKLQEKLEQLEEELLAKKKLeSERLSSAA 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  711 KEAVATLEKEHSAELERlcsSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREK 790
Cdd:pfam02463  391 KLKEEELELKSEEEKEA---QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELEL 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  791 RQE-----------VEGEHERRLDKMKEEHQQVMA-KAREQYEAEERKQRAELLGHLTGELERLQRAHERE--------- 849
Cdd:pfam02463  468 KKSedllketqlvkLQEQLELLLSRQKLEERSQKEsKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVenykvaist 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  850 LETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQE--ETARREKQQLLDVQRQVALKSEEATAT 927
Cdd:pfam02463  548 AVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidPILNLAQLDKATLEADEDDKRAKVVEG 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  928 HQQLEEAQKEHTHLLQSNQQLREI--LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNAS 1005
Cdd:pfam02463  628 ILKDTELTKLKESAKAKESGLRKGvsLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQR 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769 1006 PHFEP-DLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSA-EGVALRSAKEFLVQQTRSMRRRQTALK 1083
Cdd:pfam02463  708 EKEELkKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKeEKEEEKSELSLKEKELAEEREKTEKLK 787

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217281769 1084 AAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEASDE 1158
Cdd:pfam02463  788 VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE 862

CCDC22

pfam05667

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...

632-912

3.35e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.

Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 41.94 E-value: 3.35e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  632 TQADEDQIRAEQEASLQKLREELESQQKAERasleqKNRQMLEQLKEEIEASEKSEQAALNAAKEkaLQQLREQLEGERK 711
Cdd:pfam05667  217 AAAQEWEEEWNSQGLASRLTPEEYRKRKRTK-----LLKRIAEQLRSAALAGTEATSGASRSAQD--LAELLSSFSGSST 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  712 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKK----IQEAQQKEEAQLQKCLGQVEHRVHQksyhvagYEHELSSLL 787
Cdd:pfam05667  290 TDTGLTKGSRFTHTEKLQFTNEAPAATSSPPTKVEteeeLQQQREEELEELQEQLEDLESSIQE-------LEKEIKKLE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  788 REKRQ-EVEGEHERRLDKMKEEHQQVMAKAREQY-EAEER--------KQRAELLGHLTGELERLQRAHERELETVRQEQ 857
Cdd:pfam05667  363 SSIKQvEEELEELKEQNEELEKQYKVKKKTLDLLpDAEENiaklqalvDASAQRLVELAGQWEKHRVPLIEEYRALKEAK 442

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217281769  858 HKRLEdlrrrhrEQERKLQDLEldlETRAKdvkarlaLLEVQEETARRE--KQQLLD 912
Cdd:pfam05667  443 SNKED-------ESQRKLEEIK---ELREK-------IKEVAEEAKQKEelYKQLVA 482

COG2433

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

810-960

3.70e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.77 E-value: 3.70e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  810 QQVMAKAREQYEAEERKQR-------AELLGHLTgelERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLE--- 879
Cdd:COG2433    353 ERVEKKVPPDVDRDEVKARvirglsiEEALEELI---EKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEaev 429

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  880 LDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARK 959
Cdd:COG2433    430 EELEAELEEKDERIERLERELSEARSEERREIRKDREISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGE 509


                   .
gi 2217281769  960 L 960
Cdd:COG2433    510 L 510

Nop53

pfam07767

Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ...

840-960

4.39e-03

Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ribosomal biogenesis. They are specifically involved in the processing beyond the 27S stage of 25S rRNA maturation. This family contains sequences that bear similarity to the glioma tumour suppressor candidate region gene 2 protein (p60). This protein has been found to interact with herpes simplex type 1 regulatory proteins.

Pssm-ID: 462259 [Multi-domain] Cd Length: 353 Bit Score: 41.13 E-value: 4.39e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  840 ERLQRAHERELETVRQEQHkrLEDLRRRHREQERKLQDLELDLETRAKDVKA-RLALLEVQEETARREKQQLLDVQRQVA 918
Cdd:pfam07767  199 ELLQKAVEAEKKRLKEEEK--LERVLEKIAESAATAEAREEKRKTKAQRNKEkRRKEEEREAKEEKALKKKLAQLERLKE 276

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 2217281769  919 LKSEEAtathQQLEEAQKEHTHLLQSNQQLREILDELQARKL 960
Cdd:pfam07767  277 IAKEIA----EKEKEREEKAEARKREKRKKKKEEKKLRPRKL 314

OmpH

smart00935

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

674-760

4.40e-03

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 39.10 E-value: 4.40e-03

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769   674 EQLKEEIEASEKSEQAALNAaKEKALQQLREQLEGERkeavATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQK 753
Cdd:smart00935   17 KAAQKQLEKEFKKRQAELEK-LEKELQKLKEKLQKDA----ATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQKRQQE 91


                    ....*..
gi 2217281769   754 EEAQLQK 760
Cdd:smart00935   92 ELQKILD 98

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

540-955

4.50e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.44 E-value: 4.50e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  540 EAALKAMEEAVAQV------LEQDQRHL-LESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEAR 612
Cdd:COG4913    238 ERAHEALEDAREQIellepiRELAERYAaARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  613 MREEESQRLSwLRAQVQSSTQADEDQIRAEQEAsLQKLREELES-----QQKAERASLE--------QKNRQMLEQLKEE 679
Cdd:COG4913    318 LDALREELDE-LEAQIRGNGGDRLEQLEREIER-LERELEERERrrarlEALLAALGLPlpasaeefAALRAEAAALLEA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  680 IEASEKSEQAALNAAkEKALQQLREQLEGERKEaVATLEK------EHSAEL-ERLCSSLEAKHREV--------VSSLQ 744
Cdd:COG4913    396 LEEELEALEEALAEA-EAALRDLRRELRELEAE-IASLERrksnipARLLALrDALAEALGLDEAELpfvgelieVRPEE 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  745 KKIQEAQQK-----------EEAQLQKCLGQVE----------HRVHQKSYHVAGYEHELSSLLRE-------KRQEVEG 796
Cdd:COG4913    474 ERWRGAIERvlggfaltllvPPEHYAAALRWVNrlhlrgrlvyERVRTGLPDPERPRLDPDSLAGKldfkphpFRAWLEA 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  797 EHERRLDKMKEEHQQVMAKAR----------EQYEAEERKQR-------------AELLGHLTGELERLQRAHE------ 847
Cdd:COG4913    554 ELGRRFDYVCVDSPEELRRHPraitragqvkGNGTRHEKDDRrrirsryvlgfdnRAKLAALEAELAELEEELAeaeerl 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  848 RELETVRQEQHKRLEDLRR---------RHREQERKLQDLELDLEtRAKDVKARLALLEVQEETARRE----KQQLLDVQ 914
Cdd:COG4913    634 EALEAELDALQERREALQRlaeyswdeiDVASAEREIAELEAELE-RLDASSDDLAALEEQLEELEAEleelEEELDELK 712

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 2217281769  915 RQVALKSEEATATHQQLEEAQKEHTHLLQ-SNQQLREILDEL 955
Cdd:COG4913    713 GEIGRLEKELEQAEEELDELQDRLEAAEDlARLELRALLEER 754

hsdR

PRK11448

type I restriction enzyme EcoKI subunit R; Provisional

784-904

4.60e-03

type I restriction enzyme EcoKI subunit R; Provisional

Pssm-ID: 236912 [Multi-domain] Cd Length: 1123 Bit Score: 41.48 E-value: 4.60e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  784 SSLLREKRQEVEgeherRLDKMKEEHQQvmAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQE-QHKRLE 862
Cdd:PRK11448   141 ENLLHALQQEVL-----TLKQQLELQAR--EKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKaAETSQE 213

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2217281769  863 DLRRRHREQERKLQDLELD-LETRAK-DVKARLALLEVQEETAR 904
Cdd:PRK11448   214 RKQKRKEITDQAAKRLELSeEETRILiDQQLRKAGWEADSKTLR 257

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

839-1012

5.91e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.91 E-value: 5.91e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  839 LERLQRAHER--ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQrq 916
Cdd:COG1579      9 LLDLQELDSEldRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVR-- 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217281769  917 valKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKqhlLRE 996
Cdd:COG1579     87 ---NNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAE---LEE 160

                          170
                   ....*....|....*.
gi 2217281769  997 VTVEENNASPHFEPDL 1012
Cdd:COG1579    161 LEAEREELAAKIPPEL 176

DR0291