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Conserved domains on  [gi|2217372934|ref|XP_047278087|]
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sperm-associated antigen 1 isoform X7 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 1003384)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
3a0801s09 super family cl36792
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 141-339 1.15e-18

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


The actual alignment was detected with superfamily member TIGR00990:

Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 88.89  E-value: 1.15e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 141 GKEKYSKRPT-KKKTPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKIETRiDTAGLTEKEKDFLATREKEKGNEA 219
Cdd:TIGR00990  59 GQQQRESKPKiSKKERRKRKQAEKETEGKTEEKKSTAPKNAPVEPADELPEIDES-SVANLSEEERKKYAAKLKEKGNKA 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 220 FNSGDYEEAVMYYTRSISALPTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDL 299
Cdd:TIGR00990 138 YRNKDFNKAIKLYSKAIECKPDPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDL 217

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2217372934 300 SKVLDVEPDNDlaKKTLSEVERDLKN---SEAASETQTKGKRM 339
Cdd:TIGR00990 218 TASCIIDGFRN--EQSAQAVERLLKKfaeSKAKEILETKPENL 258
 
Name Accession Description Interval E-value
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 141-339 1.15e-18

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 88.89  E-value: 1.15e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 141 GKEKYSKRPT-KKKTPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKIETRiDTAGLTEKEKDFLATREKEKGNEA 219
Cdd:TIGR00990  59 GQQQRESKPKiSKKERRKRKQAEKETEGKTEEKKSTAPKNAPVEPADELPEIDES-SVANLSEEERKKYAAKLKEKGNKA 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 220 FNSGDYEEAVMYYTRSISALPTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDL 299
Cdd:TIGR00990 138 YRNKDFNKAIKLYSKAIECKPDPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDL 217

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2217372934 300 SKVLDVEPDNDlaKKTLSEVERDLKN---SEAASETQTKGKRM 339
Cdd:TIGR00990 218 TASCIIDGFRN--EQSAQAVERLLKKfaeSKAKEILETKPENL 258
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
215-329 3.72e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.12  E-value: 3.72e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 215 KGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLR 293
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKALELDPDdAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2217372934 294 EATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAA 329
Cdd:COG0457    94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEA 129
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 214-284 1.65e-09

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 59.42  E-value: 1.65e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217372934 214 EKGNEAFNSGDYEEAVMYYTRSISALPTVVA-YNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRAT 284
Cdd:PLN03088    7 DKAKEAFVDDDFALAVDLYTQAIDLDPNNAElYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGT 78
TPR_1 pfam00515
Tetratricopeptide repeat;
242-275 1.04e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 36.63  E-value: 1.04e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2217372934 242 VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGN 275
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 242-275 1.19e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.27  E-value: 1.19e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 2217372934  242 VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGN 275
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 141-339 1.15e-18

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 88.89  E-value: 1.15e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 141 GKEKYSKRPT-KKKTPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKIETRiDTAGLTEKEKDFLATREKEKGNEA 219
Cdd:TIGR00990  59 GQQQRESKPKiSKKERRKRKQAEKETEGKTEEKKSTAPKNAPVEPADELPEIDES-SVANLSEEERKKYAAKLKEKGNKA 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 220 FNSGDYEEAVMYYTRSISALPTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDL 299
Cdd:TIGR00990 138 YRNKDFNKAIKLYSKAIECKPDPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDL 217

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2217372934 300 SKVLDVEPDNDlaKKTLSEVERDLKN---SEAASETQTKGKRM 339
Cdd:TIGR00990 218 TASCIIDGFRN--EQSAQAVERLLKKfaeSKAKEILETKPENL 258
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
215-329 3.72e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.12  E-value: 3.72e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 215 KGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLR 293
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKALELDPDdAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2217372934 294 EATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAA 329
Cdd:COG0457    94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEA 129
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
216-331 6.14e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 77.35  E-value: 6.14e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 216 GNEAFNSGDYEEAVMYYTRSISALPTVV-AYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLRE 294
Cdd:COG0457    49 GLAYLRLGRYEEALADYEQALELDPDDAeALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2217372934 295 ATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASE 331
Cdd:COG0457   129 AIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
214-328 1.63e-14

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 72.64  E-value: 1.63e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 214 EKGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKL 292
Cdd:COG4785    78 ERGVAYDSLGDYDLAIADFDQALELDPDlAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRY 157

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2217372934 293 REATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEA 328
Cdd:COG4785   158 ELAIADLEKALELDPNDPERALWLYLAERKLDPEKA 193
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 214-329 4.48e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.29  E-value: 4.48e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 214 EKGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKL 292
Cdd:COG2956   149 ELAELYLEQGDYDEAIEALEKALKLDPDcARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDP 228

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2217372934 293 REATEDLSKVLDVEPDNDlAKKTLSEVERDLKNSEAA 329
Cdd:COG2956   229 EEALELLRKALELDPSDD-LLLALADLLERKEGLEAA 264
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 207-329 5.28e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.10  E-value: 5.28e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 207 FLATREKEKGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATT 285
Cdd:COG3914    76 LLAALLELAALLLQALGRYEEALALYRRALALNPDnAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEA 155

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2217372934 286 YKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAA 329
Cdd:COG3914   156 LRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 209-331 5.35e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.29  E-value: 5.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 209 ATREKEKGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYK 287
Cdd:COG4783     4 AEALYALAQALLLAGDYDEAEALLEKALELDPDnPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2217372934 288 HQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASE 331
Cdd:COG4783    84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIA 127
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 216-312 1.09e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 66.94  E-value: 1.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 216 GNEAFNSGDYEEAVMYYTRSISALP-TVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLRE 294
Cdd:COG3914   119 GNLLLALGRLEEALAALRRALALNPdFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEE 198

                          90
                  ....*....|....*...
gi 2217372934 295 ATEDLSKVLDVEPDNDLA 312
Cdd:COG3914   199 AIAAYRRALELDPDNADA 216
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 216-310 1.61e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 61.56  E-value: 1.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 216 GNEAFNSGDYEEAVMYYTRSISALP-TVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLRE 294
Cdd:COG4235    24 GRAYLRLGRYDEALAAYEKALRLDPdNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAE 103

                          90
                  ....*....|....*.
gi 2217372934 295 ATEDLSKVLDVEPDND 310
Cdd:COG4235   104 AIAAWQKLLALLPADA 119
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 204-307 7.78e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 60.36  E-value: 7.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 204 EKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRR 282
Cdd:COG5010    49 KLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNnPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNL 128

                          90       100
                  ....*....|....*....|....*
gi 2217372934 283 ATTYKHQNKLREATEDLSKVLDVEP 307
Cdd:COG5010   129 AALLLSLGQDDEAKAALQRALGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 215-309 9.90e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.44  E-value: 9.90e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 215 KGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLR 293
Cdd:COG4783    44 LGEILLQLGDLDEAIVLLHEALELDPDePEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPD 123

                          90
                  ....*....|....*.
gi 2217372934 294 EATEDLSKVLDVEPDN 309
Cdd:COG4783   124 EAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
244-329 1.64e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.18  E-value: 1.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 244 AYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDL 323
Cdd:COG0457    10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL 89


                  ....*.
gi 2217372934 324 KNSEAA 329
Cdd:COG0457    90 GRYEEA 95
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
223-351 1.68e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.18  E-value: 1.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 223 GDYEEAVMYYTRSISALPTVV-AYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSK 301
Cdd:COG0457    90 GRYEEALEDYDKALELDPDDAeALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEK 169

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2217372934 302 VLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEE 351
Cdd:COG0457   170 LEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAAL 219
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 222-331 4.91e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.13  E-value: 4.91e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 222 SGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLS 300
Cdd:COG2956   123 EGDWEKAIEVLERLLKLGPEnAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALE 202

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2217372934 301 KVLDVEPDNDLAKKTLSEVERDLKNSEAASE 331
Cdd:COG2956   203 RALEQDPDYLPALPRLAELYEKLGDPEEALE 233
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
219-308 5.07e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 56.33  E-value: 5.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 219 AFNSGDYEEAVMYYTRSISALP-TVVAYNNRAQAEIKLQNWNSAFQdCEKVLELEPGNVKALLRRATTYKHQNKLREATE 297
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPdNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                          90
                  ....*....|.
gi 2217372934 298 DLSKVLDVEPD 308
Cdd:COG3063    81 YLERALELDPS 91
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
224-312 9.99e-10

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 58.77  E-value: 9.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 224 DYEEAVMYYTRSISALPTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVL 303
Cdd:COG4785    55 AAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134


                  ....*....
gi 2217372934 304 DVEPDNDLA 312
Cdd:COG4785   135 ELDPDYAYA 143
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 214-284 1.65e-09

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 59.42  E-value: 1.65e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217372934 214 EKGNEAFNSGDYEEAVMYYTRSISALPTVVA-YNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRAT 284
Cdd:PLN03088    7 DKAKEAFVDDDFALAVDLYTQAIDLDPNNAElYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGT 78
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 216-331 1.14e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.28  E-value: 1.14e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 216 GNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLRE 294
Cdd:COG2956    49 GNLYRRRGEYDRAIRIHQKLLERDPDrAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEK 128

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2217372934 295 ATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASE 331
Cdd:COG2956   129 AIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIE 165
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 244-329 1.16e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.47  E-value: 1.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 244 AYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDL 323
Cdd:COG4235    19 GWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQ 98


                  ....*.
gi 2217372934 324 KNSEAA 329
Cdd:COG4235    99 GDYAEA 104
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 214-329 5.58e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.96  E-value: 5.58e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 214 EKGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKL 292
Cdd:COG2956    81 ELAQDYLKAGLLDRAEELLEKLLELDPDdAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDY 160

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2217372934 293 REATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAA 329
Cdd:COG2956   161 DEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEA 197
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 207-335 6.70e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.96  E-value: 6.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 207 FLATREKEKGNEAFNSGDYEEAVMYYTRSISALP-TVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATT 285
Cdd:COG2956     6 AAALGWYFKGLNYLLNGQPDKAIDLLEEALELDPeTVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQD 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2217372934 286 YKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTK 335
Cdd:COG2956    86 YLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLER 135
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 218-321 3.68e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 48.45  E-value: 3.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 218 EAFNSGDYEEAVMYYTRSISALP----TVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVK---ALLRRATTYKHQN 290
Cdd:COG1729     2 ALLKAGDYDEAIAAFKAFLKRYPnsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELG 81

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2217372934 291 KLREATEDLSKVLDVEPDNDLAKKTLSEVER 321
Cdd:COG1729    82 DYDKARATLEELIKKYPDSEAAKEARARLAR 112
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 216-328 2.62e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 2.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 216 GNEAFNSGDYEEAVMYYTRSISALPTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREA 295
Cdd:TIGR02917 710 GDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKA 789

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2217372934 296 TEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEA 328
Cdd:TIGR02917 790 IKHYQTVVKKAPDNAVVLNNLAWLYLELKDPRA 822
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 224-329 3.49e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.88  E-value: 3.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 224 DYEEAVMYYTRSISALPTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVL 303
Cdd:COG5010    36 NTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKAL 115

                          90       100
                  ....*....|....*....|....*.
gi 2217372934 304 DVEPDNDLAKKTLSEVERDLKNSEAA 329
Cdd:COG5010   116 ALSPDNPNAYSNLAALLLSLGQDDEA 141
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
251-329 5.06e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.78  E-value: 5.06e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217372934 251 AEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREAtEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAA 329
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEA 78
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 261-331 1.38e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.53  E-value: 1.38e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217372934 261 AFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASE 331
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEE 72
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
269-329 9.52e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.76  E-value: 9.52e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217372934 269 LELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAA 329
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEA 61
TPR_1 pfam00515
Tetratricopeptide repeat;
242-275 1.04e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 36.63  E-value: 1.04e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2217372934 242 VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGN 275
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_17 pfam13431
Tetratricopeptide repeat;
265-295 1.07e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 36.37  E-value: 1.07e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2217372934 265 CEKVLELEPGNVKALLRRATTYKHQNKLREA 295
Cdd:pfam13431   2 YLKALELDPNNADAYYNLAVLLLELGQSETA 32
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 242-275 1.19e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.27  E-value: 1.19e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 2217372934  242 VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGN 275
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 249-329 3.08e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 3.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 249 AQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEA 328
Cdd:TIGR02917 608 GRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTES 687


                  .
gi 2217372934 329 A 329
Cdd:TIGR02917 688 A 688
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 219-332 4.30e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.68  E-value: 4.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 219 AFNSGDYEEAVMYYTRSISALPTVV-AYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATE 297
Cdd:TIGR02917 169 ALAENRFDEARALIDEVLTADPGNVdALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEK 248

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2217372934 298 DLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASET 332
Cdd:TIGR02917 249 HADALLKKAPNSPLAHYLKALVDFQKKNYEDARET 283
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 248-332 4.61e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.68  E-value: 4.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 248 RAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSE 327
Cdd:TIGR02917 267 KALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVD 346


                  ....*
gi 2217372934 328 AASET 332
Cdd:TIGR02917 347 EAIAT 351
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 215-338 6.12e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 6.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217372934 215 KGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLR 293
Cdd:TIGR02917 471 LGAIYLGKGDLAKAREAFEKALSIEPDfFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEE 550

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2217372934 294 EATEDLSKVLDVEPDNDLAKKTLSEVER---DLKNSEAASETQTKGKR 338
Cdd:TIGR02917 551 EAVAWLEKAAELNPQEIEPALALAQYYLgkgQLKKALAILNEAADAAP 598
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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