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Conserved domains on  [gi|2217367097|ref|XP_047276319|]
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protein ELFN1 isoform X1 [Homo sapiens]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11471162)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR_8 pfam13855
Leucine rich repeat;
85-144 2.46e-14

Leucine rich repeat;


:

Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 67.93  E-value: 2.46e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  85 NLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLI 144
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
17-190 9.52e-14

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.20  E-value: 9.52e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  17 TLLHAGGLARADCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNEnrirsvqyaSLSRFGNLTYLNLTKNEI 96
Cdd:COG4886    55 LLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLSGNQL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  97 GYIEDgAFSGQFNLQVLQLGYNRLRNLTEGmLRGLGKLEYLYLQANLIEVVmASSFWECPNIVNIDLSMNRIQQLnSGTF 176
Cdd:COG4886   126 TDLPE-ELANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPL 201

                         170
                  ....*....|....
gi 2217367097 177 AGLAKLSVCELYSN 190
Cdd:COG4886   202 GNLTNLEELDLSGN 215
PCC super family cl28216
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 162-256 6.31e-07

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


The actual alignment was detected with superfamily member TIGR00864:

Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 53.55  E-value: 6.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  162 DLSMNRIQQLNSGTFAGLAKLSVCELYSNPFYCSCELLGFLRWLAAFTNATQTYDRMQCESPPVYSGYYLLGqgrrghrs 241
Cdd:TIGR00864    1 DISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPGALAGQPLLG-------- 72

                           90
                   ....*....|....*
gi 2217367097  242 iLSKLQSVCTEDSYA 256
Cdd:TIGR00864   73 -IPLLDSGCDEEYVA 86
 
Name Accession Description Interval E-value
LRR_8 pfam13855
Leucine rich repeat;
85-144 2.46e-14

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 67.93  E-value: 2.46e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  85 NLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLI 144
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
17-190 9.52e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.20  E-value: 9.52e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  17 TLLHAGGLARADCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNEnrirsvqyaSLSRFGNLTYLNLTKNEI 96
Cdd:COG4886    55 LLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLSGNQL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  97 GYIEDgAFSGQFNLQVLQLGYNRLRNLTEGmLRGLGKLEYLYLQANLIEVVmASSFWECPNIVNIDLSMNRIQQLnSGTF 176
Cdd:COG4886   126 TDLPE-ELANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPL 201

                         170
                  ....*....|....
gi 2217367097 177 AGLAKLSVCELYSN 190
Cdd:COG4886   202 GNLTNLEELDLSGN 215
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 162-256 6.31e-07

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 53.55  E-value: 6.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  162 DLSMNRIQQLNSGTFAGLAKLSVCELYSNPFYCSCELLGFLRWLAAFTNATQTYDRMQCESPPVYSGYYLLGqgrrghrs 241
Cdd:TIGR00864    1 DISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPGALAGQPLLG-------- 72

                           90
                   ....*....|....*
gi 2217367097  242 iLSKLQSVCTEDSYA 256
Cdd:TIGR00864   73 -IPLLDSGCDEEYVA 86
LRRCT smart00082
Leucine rich repeat C-terminal domain;
190-228 9.73e-07

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 46.27  E-value: 9.73e-07
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 2217367097  190 NPFYCSCELLGFLRWLAAFTnATQTYDRMQCESPPVYSG 228
Cdd:smart00082   1 NPFICDCELRWLLRWLQANE-HLQDPVDLRCASPSSLRG 38
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 65-147 1.47e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 49.78  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  65 LRLNENRIRSVQyaSLSRFGNLTYLNLTKNEIGYIEDgaFSGQFNLQVLQLGYNRLRNLtEGmLRGLGKLEYLYLQANLI 144
Cdd:cd21340     7 LYLNDKNITKID--NLSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKI-EN-LENLVNLKKLYLGGNRI 80


                  ...
gi 2217367097 145 EVV 147
Cdd:cd21340    81 SVV 83
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 86-190 4.50e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.60  E-value: 4.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  86 LTYLNLTKNEI-GYIEDgaFSGQFNLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLIEVVMASSFWECPNIVNIDLS 164
Cdd:PLN00113  454 LQMLSLARNKFfGGLPD--SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLS 531

                          90       100
                  ....*....|....*....|....*.
gi 2217367097 165 MNRIQQLNSGTFAGLAKLSVCELYSN 190
Cdd:PLN00113  532 HNQLSGQIPASFSEMPVLSQLDLSQN 557
 
Name Accession Description Interval E-value
LRR_8 pfam13855
Leucine rich repeat;
85-144 2.46e-14

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 67.93  E-value: 2.46e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  85 NLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLI 144
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
17-190 9.52e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.20  E-value: 9.52e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  17 TLLHAGGLARADCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNEnrirsvqyaSLSRFGNLTYLNLTKNEI 96
Cdd:COG4886    55 LLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLSGNQL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  97 GYIEDgAFSGQFNLQVLQLGYNRLRNLTEGmLRGLGKLEYLYLQANLIEVVmASSFWECPNIVNIDLSMNRIQQLnSGTF 176
Cdd:COG4886   126 TDLPE-ELANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPL 201

                         170
                  ....*....|....
gi 2217367097 177 AGLAKLSVCELYSN 190
Cdd:COG4886   202 GNLTNLEELDLSGN 215
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
65-210 1.89e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 73.04  E-value: 1.89e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  65 LRLNENRIRSVQyASLSRFGNLTYLNLTKNEIGYIEDgAFSGQFNLQVLQLGYNRLRNLTEGmLRGLGKLEYLYLQANLI 144
Cdd:COG4886   118 LDLSGNQLTDLP-EELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQI 194

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217367097 145 EvVMASSFWECPNIVNIDLSMNRIQQLnSGTFAGLAKLSVCELYSNPfycscelLGFLRWLAAFTN 210
Cdd:COG4886   195 T-DLPEPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQ-------LTDLPELGNLTN 251
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
65-202 4.39e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.81  E-value: 4.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  65 LRLNENRIRSVQyASLSRFGNLTYLNLTKNEIGYIEDgAFSGQFNLQVLQLGYNRLRNLTEgmLRGLGKLEYLYLQANLI 144
Cdd:COG4886   187 LDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQL 262

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2217367097 145 EVVmaSSFWECPNIVNIDLSMNRIQQLNSGTFAGLAKLSVCELYSNPFYCSCELLGFL 202
Cdd:COG4886   263 TDL--PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLL 318
LRR_8 pfam13855
Leucine rich repeat;
109-168 3.85e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 53.30  E-value: 3.85e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097 109 NLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLIEVVMASSFWECPNIVNIDLSMNRI 168
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
65-120 5.64e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.22  E-value: 5.64e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217367097  65 LRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRL 120
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 162-256 6.31e-07

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 53.55  E-value: 6.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  162 DLSMNRIQQLNSGTFAGLAKLSVCELYSNPFYCSCELLGFLRWLAAFTNATQTYDRMQCESPPVYSGYYLLGqgrrghrs 241
Cdd:TIGR00864    1 DISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPGALAGQPLLG-------- 72

                           90
                   ....*....|....*
gi 2217367097  242 iLSKLQSVCTEDSYA 256
Cdd:TIGR00864   73 -IPLLDSGCDEEYVA 86
LRRCT smart00082
Leucine rich repeat C-terminal domain;
190-228 9.73e-07

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 46.27  E-value: 9.73e-07
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 2217367097  190 NPFYCSCELLGFLRWLAAFTnATQTYDRMQCESPPVYSG 228
Cdd:smart00082   1 NPFICDCELRWLLRWLQANE-HLQDPVDLRCASPSSLRG 38
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 65-147 1.47e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 49.78  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  65 LRLNENRIRSVQyaSLSRFGNLTYLNLTKNEIGYIEDgaFSGQFNLQVLQLGYNRLRNLtEGmLRGLGKLEYLYLQANLI 144
Cdd:cd21340     7 LYLNDKNITKID--NLSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKI-EN-LENLVNLKKLYLGGNRI 80


                  ...
gi 2217367097 145 EVV 147
Cdd:cd21340    81 SVV 83
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 34-168 7.81e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 42.85  E-value: 7.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  34 GDKGFVWLAicsqnqppyEAIpqQINSTIVDLRLNENRIrSVQYA-----SLSRFGNLTYLNLTKNEIGyiEDGAFSGQF 108
Cdd:COG5238   249 GDEGVIALA---------EAL--KNNTTVETLYLSGNQI-GAEGAialakALQGNTTLTSLDLSVNRIG--DEGAIALAE 314

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217367097 109 NLQ------VLQLGYNRLRNltEGM------LRGLGKLEYLYLQANLIE----VVMASSFWECPNIVNIDLSMNRI 168
Cdd:COG5238   315 GLQgnktlhTLNLAYNGIGA--QGAialakaLQENTTLHSLDLSDNQIGdegaIALAKYLEGNTTLRELNLGKNNI 388
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
 85-195 3.36e-03

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 38.29  E-value: 3.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  85 NLTYLNLTKNeIGYIEDGAFSGQFNLQVLQLGYNrlrnltegmLRGLG-------KLEYLYLQANL--IEVvmaSSFWEC 155
Cdd:pfam13306  12 SLTSITIPSS-LTSIGEYAFSNCTSLKSITLPSS---------LTSIGsyafyncSLTSITIPSSLtsIGE---YAFSNC 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2217367097 156 PNIVNIDLSmNRIQQLNSGTFAG--LAKLSVC----ELYSNPFY-CS 195
Cdd:pfam13306  79 SNLKSITLP-SNLTSIGSYAFSNcsLKSITIPssvtTIGSYAFSnCS 124
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 86-190 4.50e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.60  E-value: 4.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217367097  86 LTYLNLTKNEI-GYIEDgaFSGQFNLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLIEVVMASSFWECPNIVNIDLS 164
Cdd:PLN00113  454 LQMLSLARNKFfGGLPD--SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLS 531

                          90       100
                  ....*....|....*....|....*.
gi 2217367097 165 MNRIQQLNSGTFAGLAKLSVCELYSN 190
Cdd:PLN00113  532 HNQLSGQIPASFSEMPVLSQLDLSQN 557
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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