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Conserved domains on  [gi|2207073696|ref|XP_046977928|]
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toll-like receptor 7 [Vanessa cardui]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
239-643 8.55e-26

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 111.56  E-value: 8.55e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  239 FSDLLSLKVVNLSENAINYLPEGLFQNTREIREIYLSYNELEIMPKKLFNRLEQLVVLDLSANKLKGDHIEAETFGGLIR 318
Cdd:COG4886     18 LELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTN 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  319 LIVLDLSHNaftgvaqNMFKDLFFLQILNLSNNSIGFIEDnAFSPLFNLHTLNLAVNKLRTIEDhvfnglfilnklnlnn 398
Cdd:COG4886     98 LTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPE---------------- 153
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  399 nilsyvaenAFRNCSDLKELDLSSNKLTKVPEAILQLPFLKSLDLGENLLTEISnNSFQNLSQLTGLRLIDNQIGNLTSG 478
Cdd:COG4886    154 ---------PLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEP 223
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  479 MFwGLPSLQVLNLAKNKIQSIetETFQRNVQLEAVRLDGNFISDInGVFVSLTKLLWLNLSENHLVWFDYAFIPPGLKWL 558
Cdd:COG4886    224 LA-NLTNLETLDLSNNQLTDL--PELGNLTNLEELDLSNNQLTDL-PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLN 299
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  559 DIHANFIEVLGNYYKIQNNLNVKTLDASHNRIVTLNKMSIPNSVELLFINNNFISSIEPDSFLEKNNLTRVDMYANEIES 638
Cdd:COG4886    300 SLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATL 379

                   ....*
gi 2207073696  639 LDINS 643
Cdd:COG4886    380 LTLAL 384
TIR smart00255
Toll - interleukin 1 - resistance;
1026-1162 2.39e-22

Toll - interleukin 1 - resistance;


:

Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 94.31  E-value: 2.39e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  1026 YDAYICYSPKDeeFVIESLARELENGYPSYHLCLHYRDVPqfeaTYAQFPDLVVEATEASRRIIVVLSKNFILTEWSQVE 1105
Cdd:smart00255    2 YDVFISYSGKE--DVRNEFLSHLLEKLRGYGLCVFIDDFE----PGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDE 75
                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2207073696  1106 FRQALQRALRKNPHKLIIVAVGLVARDP-ELKSYFKTGLEITW------KEKRFWERLRYAMPS 1162
Cdd:smart00255   76 LVAALENALEEGGLRVIPIFYEVIPSDVrKQPGKFRKVFKKNYlkwpedEKEQFWKKALYAVPS 139
PPP1R42 super family cl42388
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
804-904 3.57e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


The actual alignment was detected with superfamily member cd21340:

Pssm-ID: 455733 [Multi-domain]  Cd Length: 220  Bit Score: 61.34  E-value: 3.57e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  804 LYLNSSSVNNIKNetFRSLNDLRILHLDDNKIRYLRGLEFskLSNLKELYLQNNVIEFISNdsFSFLLALEVLRLDGNRL 883
Cdd:cd21340      7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIENLEF--LTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI 80
                           90       100
                   ....*....|....*....|.
gi 2207073696  884 VNygLWHLDNNKKLQTLFVGN 904
Cdd:cd21340     81 SV--VEGLENLTNLEELHIEN 99
PPP1R42 super family cl42388
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
83-329 1.40e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


The actual alignment was detected with superfamily member cd00116:

Pssm-ID: 455733 [Multi-domain]  Cd Length: 319  Bit Score: 51.59  E-value: 1.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696   83 HYFGKMQGLTEITLSDCKILRLPGNVFEGLRGLKTLKLRSMNNqwghnkeldlslgafNGLRELHTLDLGynnirKIPSD 162
Cdd:cd00116     75 QGLTKGCGLQELDLSDNALGPDGCGVLESLLRSSSLQELKLNN---------------NGLGDRGLRLLA-----KGLKD 134
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  163 LFCALEniiSLNLTRNKIKF--VDELGFGHKCGSTLQTIDLSYNDIMS--LPADSEIL-HLRRLTQLFLQNNKISELPG- 236
Cdd:cd00116    135 LPPALE---KLVLGRNRLEGasCEALAKALRANRDLKELNLANNGIGDagIRALAEGLkANCNLEVLDLNNNGLTDEGAs 211
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  237 ---EVFSDLLSLKVVNLSENAIN-----YLPEGLFQNTREIREIYLSYNELEIMPKKLFNRL----EQLVVLDLSANKLK 304
Cdd:cd00116    212 alaETLASLKSLEVLNLGDNNLTdagaaALASALLSPNISLLTLSLSCNDITDDGAKDLAEVlaekESLLELDLRGNKFG 291
                          250       260
                   ....*....|....*....|....*...
gi 2207073696  305 --GDHIEAETFGGLI-RLIVLDLSHNAF 329
Cdd:cd00116    292 eeGAQLLAESLLEPGnELESLWVKDDSF 319
LRRNT smart00013
Leucine rich repeat N-terminal domain;
742-779 2.02e-04

Leucine rich repeat N-terminal domain;


:

Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 39.61  E-value: 2.02e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 2207073696   742 CPNNCSCyHDStkttnVVDCSVKQLDAVPRDFPNGATH 779
Cdd:smart00013    2 CPAPCNC-SGT-----AVDCSGRGLTEVPLDLPPDTTL 33
LRRCT super family cl47026
Leucine rich repeat C-terminal domain;
662-719 5.01e-03

Leucine rich repeat C-terminal domain;


The actual alignment was detected with superfamily member smart00082:

Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 36.25  E-value: 5.01e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696   662 NPFRCDCTMKWLLLINsittREYPRVMDLENVICKESyvrGVKYLPVSSLHTKDFLCK 719
Cdd:smart00082    1 NPFICDCELRWLLRWL----QANEHLQDPVDLRCASP---SSLRGPLLELLHSEFKCP 51
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
239-643 8.55e-26

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 111.56  E-value: 8.55e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  239 FSDLLSLKVVNLSENAINYLPEGLFQNTREIREIYLSYNELEIMPKKLFNRLEQLVVLDLSANKLKGDHIEAETFGGLIR 318
Cdd:COG4886     18 LELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTN 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  319 LIVLDLSHNaftgvaqNMFKDLFFLQILNLSNNSIGFIEDnAFSPLFNLHTLNLAVNKLRTIEDhvfnglfilnklnlnn 398
Cdd:COG4886     98 LTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPE---------------- 153
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  399 nilsyvaenAFRNCSDLKELDLSSNKLTKVPEAILQLPFLKSLDLGENLLTEISnNSFQNLSQLTGLRLIDNQIGNLTSG 478
Cdd:COG4886    154 ---------PLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEP 223
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  479 MFwGLPSLQVLNLAKNKIQSIetETFQRNVQLEAVRLDGNFISDInGVFVSLTKLLWLNLSENHLVWFDYAFIPPGLKWL 558
Cdd:COG4886    224 LA-NLTNLETLDLSNNQLTDL--PELGNLTNLEELDLSNNQLTDL-PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLN 299
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  559 DIHANFIEVLGNYYKIQNNLNVKTLDASHNRIVTLNKMSIPNSVELLFINNNFISSIEPDSFLEKNNLTRVDMYANEIES 638
Cdd:COG4886    300 SLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATL 379

                   ....*
gi 2207073696  639 LDINS 643
Cdd:COG4886    380 LTLAL 384
TIR smart00255
Toll - interleukin 1 - resistance;
1026-1162 2.39e-22

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 94.31  E-value: 2.39e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  1026 YDAYICYSPKDeeFVIESLARELENGYPSYHLCLHYRDVPqfeaTYAQFPDLVVEATEASRRIIVVLSKNFILTEWSQVE 1105
Cdd:smart00255    2 YDVFISYSGKE--DVRNEFLSHLLEKLRGYGLCVFIDDFE----PGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDE 75
                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2207073696  1106 FRQALQRALRKNPHKLIIVAVGLVARDP-ELKSYFKTGLEITW------KEKRFWERLRYAMPS 1162
Cdd:smart00255   76 LVAALENALEEGGLRVIPIFYEVIPSDVrKQPGKFRKVFKKNYlkwpedEKEQFWKKALYAVPS 139
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
128-543 2.05e-17

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 88.37  E-value: 2.05e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  128 GHNKELDLSLGAFnGLRELHTLDLGYNNIR-KIPSDLFCALENIISLNLTRNKIKFVDELGFghkcGSTLQTIDLSyNDI 206
Cdd:PLN00113    78 GKNISGKISSAIF-RLPYIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTGSIPRGS----IPNLETLDLS-NNM 151
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  207 MSLPADSEILHLRRLTQLFLQNNKIS-ELPGEVfSDLLSLKVVNLSENA-INYLPEGLFQnTREIREIYLSYNEL--EIm 282
Cdd:PLN00113   152 LSGEIPNDIGSFSSLKVLDLGGNVLVgKIPNSL-TNLTSLEFLTLASNQlVGQIPRELGQ-MKSLKWIYLGYNNLsgEI- 228
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  283 PKKLfNRLEQLVVLDLSANKLKG-----------------------DHIEAETFgGLIRLIVLDLSHNAFTGVAQNMFKD 339
Cdd:PLN00113   229 PYEI-GGLTSLNHLDLVYNNLTGpipsslgnlknlqylflyqnklsGPIPPSIF-SLQKLISLDLSDNSLSGEIPELVIQ 306
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  340 LFFLQILNL-SNNSIGFIEDnAFSPLFNLHTLNLAVNKlrtiedhvFNGLfilnklnlnnnilsyVAENAFRNcSDLKEL 418
Cdd:PLN00113   307 LQNLEILHLfSNNFTGKIPV-ALTSLPRLQVLQLWSNK--------FSGE---------------IPKNLGKH-NNLTVL 361
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  419 DLSSNKLT-KVPEAILQLPFLKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQI-GNLTSGM----------------- 479
Cdd:PLN00113   362 DLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFsGELPSEFtklplvyfldisnnnlq 441
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696  480 ------FWGLPSLQVLNLAKNKIqSIETETFQRNVQLEAVRLDGNFISD-INGVFVSLTKLLWLNLSENHL 543
Cdd:PLN00113   442 grinsrKWDMPSLQMLSLARNKF-FGGLPDSFGSKRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSENKL 511
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
167-353 6.92e-15

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 75.21  E-value: 6.92e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  167 LENIISLNLTRNKIKFVDELgfgHKCGStLQTIDLSYNDIMSLPAdseILHLRRLTQLFLQNNKISELPGevFSDLLSLK 246
Cdd:cd21340      1 LKRITHLYLNDKNITKIDNL---SLCKN-LKVLYLYDNKITKIEN---LEFLTNLTHLYLQNNQIEKIEN--LENLVNLK 71
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  247 VVNLSENAINYLpEGLfQNTREIREIYLSY------NELEIMPKKLFNRLEQLVVLDLSANKLKgdhiEAETFGGLIRLI 320
Cdd:cd21340     72 KLYLGGNRISVV-EGL-ENLTNLEELHIENqrlppgEKLTFDPRSLAALSNSLRVLNISGNNID----SLEPLAPLRNLE 145
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2207073696  321 VLDLSHNAFTGVAQ--NMFKDLFFLQILNLSNNSI 353
Cdd:cd21340    146 QLDASNNQISDLEEllDLLSSWPSLRELDLTGNPV 180
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
804-904 3.57e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 61.34  E-value: 3.57e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  804 LYLNSSSVNNIKNetFRSLNDLRILHLDDNKIRYLRGLEFskLSNLKELYLQNNVIEFISNdsFSFLLALEVLRLDGNRL 883
Cdd:cd21340      7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIENLEF--LTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI 80
                           90       100
                   ....*....|....*....|.
gi 2207073696  884 VNygLWHLDNNKKLQTLFVGN 904
Cdd:cd21340     81 SV--VEGLENLTNLEELHIEN 99
TIR_2 pfam13676
TIR domain; This is a family of Toll-like receptors.
1029-1137 4.15e-10

TIR domain; This is a family of Toll-like receptors.


Pssm-ID: 463954 [Multi-domain]  Cd Length: 118  Bit Score: 58.48  E-value: 4.15e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 1029 YICYSPKDEEFViESLARELE-NGYpsyHLCLHYRDVPqfeaTYAQFPDLVVEATEASRRIIVVLSKNFILTEWSQVEFR 1107
Cdd:pfam13676    2 FISYAGEDRAWA-EWLADALEaAGY---RVWLDRWDIR----PGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWE 73
                           90       100       110
                   ....*....|....*....|....*....|
gi 2207073696 1108 QALQRALRKNphKLIIVAVGLVARDPELKS 1137
Cdd:pfam13676   74 AALADPEGRK--RLIPVRLECDLELPGLAG 101
LRR_8 pfam13855
Leucine rich repeat;
825-883 7.15e-10

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 55.99  E-value: 7.15e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696  825 LRILHLDDNKIRYLRGLEFSKLSNLKELYLQNNVIEFISNDSFSFLLALEVLRLDGNRL 883
Cdd:pfam13855    3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
219-279 2.73e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 54.45  E-value: 2.73e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696  219 RRLTQLFLQNNKISELPGEVFSDLLSLKVVNLSENAINYLPEGLFQNTREIREIYLSYNEL 279
Cdd:pfam13855    1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
778-905 2.53e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 57.64  E-value: 2.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  778 THIYLDGNNYNVLNESVFNsMHKAMVLYLNSSSVNNIkNETFRSLNDLRILHLDDNKIRYLrGLEFSKLSNLKELYLQNN 857
Cdd:COG4886    116 ESLDLSGNQLTDLPEELAN-LTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNN 192
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2207073696  858 VIEFISnDSFSFLLALEVLRLDGNRLVNYGLWhLDNNKKLQTLFVGNN 905
Cdd:COG4886    193 QITDLP-EPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNN 238
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
83-329 1.40e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 51.59  E-value: 1.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696   83 HYFGKMQGLTEITLSDCKILRLPGNVFEGLRGLKTLKLRSMNNqwghnkeldlslgafNGLRELHTLDLGynnirKIPSD 162
Cdd:cd00116     75 QGLTKGCGLQELDLSDNALGPDGCGVLESLLRSSSLQELKLNN---------------NGLGDRGLRLLA-----KGLKD 134
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  163 LFCALEniiSLNLTRNKIKF--VDELGFGHKCGSTLQTIDLSYNDIMS--LPADSEIL-HLRRLTQLFLQNNKISELPG- 236
Cdd:cd00116    135 LPPALE---KLVLGRNRLEGasCEALAKALRANRDLKELNLANNGIGDagIRALAEGLkANCNLEVLDLNNNGLTDEGAs 211
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  237 ---EVFSDLLSLKVVNLSENAIN-----YLPEGLFQNTREIREIYLSYNELEIMPKKLFNRL----EQLVVLDLSANKLK 304
Cdd:cd00116    212 alaETLASLKSLEVLNLGDNNLTdagaaALASALLSPNISLLTLSLSCNDITDDGAKDLAEVlaekESLLELDLRGNKFG 291
                          250       260
                   ....*....|....*....|....*...
gi 2207073696  305 --GDHIEAETFGGLI-RLIVLDLSHNAF 329
Cdd:cd00116    292 eeGAQLLAESLLEPGnELESLWVKDDSF 319
LRR_8 pfam13855
Leucine rich repeat;
144-206 4.77e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.21  E-value: 4.77e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2207073696  144 RELHTLDLGYNNIRKIPSDLFCALENIISLNLTRNKIKFVDELGFGHkCGStLQTIDLSYNDI 206
Cdd:pfam13855    1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSG-LPS-LRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
131-286 2.16e-05

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 48.92  E-value: 2.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  131 KELDLSLGAFNGL-----RELHTLDLGYNNIRKIPSDLfcaLENIISLNLTRNKIKFVDE-LGFGhkcgstLQTIDLSYN 204
Cdd:PRK15370   265 QSLDLFHNKISCLpenlpEELRYLSVYDNSIRTLPAHL---PSGITHLNVQSNSLTALPEtLPPG------LKTLEAGEN 335
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  205 DIMSLPADSEilhlRRLTQLFLQNNKISELPGEVFSDLLSLKVvnlSENAINYLPEGLfqnTREIREIYLSYNELEIMPK 284
Cdd:PRK15370   336 ALTSLPASLP----PELQVLDVSKNQITVLPETLPPTITTLDV---SRNALTNLPENL---PAALQIMQASRNNLVRLPE 405

                   ..
gi 2207073696  285 KL 286
Cdd:PRK15370   406 SL 407
LRRNT smart00013
Leucine rich repeat N-terminal domain;
742-779 2.02e-04

Leucine rich repeat N-terminal domain;


Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 39.61  E-value: 2.02e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 2207073696   742 CPNNCSCyHDStkttnVVDCSVKQLDAVPRDFPNGATH 779
Cdd:smart00013    2 CPAPCNC-SGT-----AVDCSGRGLTEVPLDLPPDTTL 33
LRRNT pfam01462
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
742-774 8.27e-04

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 396168 [Multi-domain]  Cd Length: 28  Bit Score: 37.99  E-value: 8.27e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2207073696  742 CPNNCSCyHDStkttnVVDCSVKQLDAVPRDFP 774
Cdd:pfam01462    2 CPVPCHC-SAT-----VVNCSDRGLTAVPRDLP 28
LRRCT smart00082
Leucine rich repeat C-terminal domain;
662-719 5.01e-03

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 36.25  E-value: 5.01e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696   662 NPFRCDCTMKWLLLINsittREYPRVMDLENVICKESyvrGVKYLPVSSLHTKDFLCK 719
Cdd:smart00082    1 NPFICDCELRWLLRWL----QANEHLQDPVDLRCASP---SSLRGPLLELLHSEFKCP 51
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
45-243 6.40e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 40.54  E-value: 6.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696   45 NVRTLSSDRDVIGSmhsDGAERLAircgSHLLESTlkdhyfgkmqGLTEITLSDCKI----LRLPGNVFEGLRGLKTLKL 120
Cdd:COG5238    209 TVTTLWLKRNPIGD---EGAEILA----EALKGNK----------SLTTLDLSNNQIgdegVIALAEALKNNTTVETLYL 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  121 RSmnNQWGHN---------------KELDLSL------GAF---NGLRE---LHTLDLGYNNIRK---IPsdLFCALE-- 168
Cdd:COG5238    272 SG--NQIGAEgaialakalqgnttlTSLDLSVnrigdeGAIalaEGLQGnktLHTLNLAYNGIGAqgaIA--LAKALQen 347
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  169 -NIISLNLTRNKI--KFVDELGFGHKCGSTLQTIDLSYNDIMSLPADSEILHLR--RLTQLFLQNNKISELPGEVFSDLL 243
Cdd:COG5238    348 tTLHSLDLSDNQIgdEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQtnRLHTLILDGNLIGAEAQQRLEQLL 427
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
239-643 8.55e-26

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 111.56  E-value: 8.55e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  239 FSDLLSLKVVNLSENAINYLPEGLFQNTREIREIYLSYNELEIMPKKLFNRLEQLVVLDLSANKLKGDHIEAETFGGLIR 318
Cdd:COG4886     18 LELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTN 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  319 LIVLDLSHNaftgvaqNMFKDLFFLQILNLSNNSIGFIEDnAFSPLFNLHTLNLAVNKLRTIEDhvfnglfilnklnlnn 398
Cdd:COG4886     98 LTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPE---------------- 153
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  399 nilsyvaenAFRNCSDLKELDLSSNKLTKVPEAILQLPFLKSLDLGENLLTEISnNSFQNLSQLTGLRLIDNQIGNLTSG 478
Cdd:COG4886    154 ---------PLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEP 223
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  479 MFwGLPSLQVLNLAKNKIQSIetETFQRNVQLEAVRLDGNFISDInGVFVSLTKLLWLNLSENHLVWFDYAFIPPGLKWL 558
Cdd:COG4886    224 LA-NLTNLETLDLSNNQLTDL--PELGNLTNLEELDLSNNQLTDL-PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLN 299
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  559 DIHANFIEVLGNYYKIQNNLNVKTLDASHNRIVTLNKMSIPNSVELLFINNNFISSIEPDSFLEKNNLTRVDMYANEIES 638
Cdd:COG4886    300 SLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATL 379

                   ....*
gi 2207073696  639 LDINS 643
Cdd:COG4886    380 LTLAL 384
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
124-594 1.06e-24

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 108.48  E-value: 1.06e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  124 NNQWGHNKELDLSLGAFNGLRELHTLDLGYNNIRKIPSDLFCALENIISLNLTRNKIKFVDELGFGHKCGSTLQTIDLSY 203
Cdd:COG4886      1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  204 NDIMSLPADSEILHLRRLTQLFLQNNkiselpgEVFSDLLSLKVVNLSENAINYLPEGLFQNTReIREIYLSYNELEIMP 283
Cdd:COG4886     81 LLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELANLTN-LKELDLSNNQLTDLP 152
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  284 KKLFNrLEQLVVLDLSANKLKGdhIEAEtFGGLIRLIVLDLSHNaftgvaqnmfkdlfflQILNLSNnsigfiednAFSP 363
Cdd:COG4886    153 EPLGN-LTNLKSLDLSNNQLTD--LPEE-LGNLTNLKELDLSNN----------------QITDLPE---------PLGN 203
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  364 LFNLHTLNLAVNKLRTIEDhvfnglfilnklnlnnnilsyvaenAFRNCSDLKELDLSSNKLTKVPEaILQLPFLKSLDL 443
Cdd:COG4886    204 LTNLEELDLSGNQLTDLPE-------------------------PLANLTNLETLDLSNNQLTDLPE-LGNLTNLEELDL 257
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  444 GENLLTEISNNSfqNLSQLTGLRLIDNQIGNLTSGMFWGLPSLQVLNLakNKIQSIETETFQRNVQLEAVRLDGNFISDI 523
Cdd:COG4886    258 SNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLL--LLLLLNLLELLILLLLLTTLLLLLLLLKGL 333
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696  524 NGVFVSLTKLLWLNLSENHLVWFDYAFIPPGLKWLDIHANFIEVLGNYYKIQNNLNVKTLDASHNRIVTLN 594
Cdd:COG4886    334 LVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLT 404
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
131-462 1.20e-23

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 105.40  E-value: 1.20e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  131 KELDLS-LGAFNGLRELHTLDLGYNNIRKIPSDLFcALENIISLNLTRNKIK-FVDELGfghKCgSTLQTIDLSYNDIMS 208
Cdd:COG4886     99 TELDLSgNEELSNLTNLESLDLSGNQLTDLPEELA-NLTNLKELDLSNNQLTdLPEPLG---NL-TNLKSLDLSNNQLTD 173
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  209 LPadSEILHLRRLTQLFLQNNKISELPgEVFSDLLSLKVVNLSENAINYLPEGLFQNTReIREIYLSYNELEIMPKklFN 288
Cdd:COG4886    174 LP--EELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEPLANLTN-LETLDLSNNQLTDLPE--LG 247
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  289 RLEQLVVLDLSANKLKgdhiEAETFGGLIRLIVLDLSHNAFTGVAqnmFKDLFFLQILNLSNNSIGFIEDNAFSPLFNLH 368
Cdd:COG4886    248 NLTNLEELDLSNNQLT----DLPPLANLTNLKTLDLSNNQLTDLK---LKELELLLGLNSLLLLLLLLNLLELLILLLLL 320
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  369 TLNLAVNKLRTIEDHVFNGLFILNKLNLNNNILSYVAENAFRNCSDLKELDLSSNKLTKVPEAILQLPFLKSLDLGENLL 448
Cdd:COG4886    321 TTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGV 400
                          330
                   ....*....|....
gi 2207073696  449 TEISNNSFQNLSQL 462
Cdd:COG4886    401 LLLTLALLDAVNTE 414
TIR smart00255
Toll - interleukin 1 - resistance;
1026-1162 2.39e-22

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 94.31  E-value: 2.39e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  1026 YDAYICYSPKDeeFVIESLARELENGYPSYHLCLHYRDVPqfeaTYAQFPDLVVEATEASRRIIVVLSKNFILTEWSQVE 1105
Cdd:smart00255    2 YDVFISYSGKE--DVRNEFLSHLLEKLRGYGLCVFIDDFE----PGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDE 75
                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2207073696  1106 FRQALQRALRKNPHKLIIVAVGLVARDP-ELKSYFKTGLEITW------KEKRFWERLRYAMPS 1162
Cdd:smart00255   76 LVAALENALEEGGLRVIPIFYEVIPSDVrKQPGKFRKVFKKNYlkwpedEKEQFWKKALYAVPS 139
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
107-508 2.87e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 95.00  E-value: 2.87e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  107 NVFEGLRGLKTLKLRSMNNQWGHNKELDLSLGAFNGLRELHTLDLGYNNIRKIPSDLFCALENIISLNLTRNKIKFVDEL 186
Cdd:COG4886      8 LTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLL 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  187 GFGHKCGST-LQTIDLSYNDimslpadsEILHLRRLTQLFLQNNKISELPGEvFSDLLSLKVVNLSENAINYLPEGLFQN 265
Cdd:COG4886     88 GLTDLGDLTnLTELDLSGNE--------ELSNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLSNNQLTDLPEPLGNL 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  266 TrEIREIYLSYNELEIMPKKLFNrLEQLVVLDLSANKLKgdhIEAETFGGLIRLIVLDLSHNAFTGVAQNmFKDLFFLQI 345
Cdd:COG4886    159 T-NLKSLDLSNNQLTDLPEELGN-LTNLKELDLSNNQIT---DLPEPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLET 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  346 LNLSNNSIGFIEDnaFSPLFNLHTLNLAVNKLRTIEDhvfnglfilnklnlnnnilsyvaenaFRNCSDLKELDLSSNKL 425
Cdd:COG4886    233 LDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLPP--------------------------LANLTNLKTLDLSNNQL 284
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  426 T----KVPEAILQLPFLKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQIGNLTSGMFWGLPSLQVLNLAKNKIQSIET 501
Cdd:COG4886    285 TdlklKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLT 364

                   ....*..
gi 2207073696  502 ETFQRNV 508
Cdd:COG4886    365 LLLTLGL 371
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-408 4.35e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 91.53  E-value: 4.35e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696   85 FGKMQGLTEITLSDCKILRLPGNvFEGLRGLKTLKLRsmNNQWghnKELDLSLGafnGLRELHTLDLGYNNIRKIPSDLF 164
Cdd:COG4886    109 LSNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLS--NNQL---TDLPEPLG---NLTNLKSLDLSNNQLTDLPEELG 179
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  165 cALENIISLNLTRNKIKFV-DELGfghKCgSTLQTIDLSYNDIMSLPAdsEILHLRRLTQLFLQNNKISELPGevFSDLL 243
Cdd:COG4886    180 -NLTNLKELDLSNNQITDLpEPLG---NL-TNLEELDLSGNQLTDLPE--PLANLTNLETLDLSNNQLTDLPE--LGNLT 250
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  244 SLKVVNLSENAINYLPEGLfqNTREIREIYLSYNELEIMPKKLFNRLEQLVVLDLSANKLKGDHIEAETFGGLIRLIVLD 323
Cdd:COG4886    251 NLEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLL 328
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  324 LSHNAFTGVAQNMFKDLFFLQILNLSNNSIGFIEDNAFSPLFNLHTLNLAVNKLRTIEDHVFNGLFILNKLNLNNNILSY 403
Cdd:COG4886    329 LLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALL 408

                   ....*
gi 2207073696  404 VAENA 408
Cdd:COG4886    409 DAVNT 413
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
128-543 2.05e-17

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 88.37  E-value: 2.05e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  128 GHNKELDLSLGAFnGLRELHTLDLGYNNIR-KIPSDLFCALENIISLNLTRNKIKFVDELGFghkcGSTLQTIDLSyNDI 206
Cdd:PLN00113    78 GKNISGKISSAIF-RLPYIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTGSIPRGS----IPNLETLDLS-NNM 151
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  207 MSLPADSEILHLRRLTQLFLQNNKIS-ELPGEVfSDLLSLKVVNLSENA-INYLPEGLFQnTREIREIYLSYNEL--EIm 282
Cdd:PLN00113   152 LSGEIPNDIGSFSSLKVLDLGGNVLVgKIPNSL-TNLTSLEFLTLASNQlVGQIPRELGQ-MKSLKWIYLGYNNLsgEI- 228
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  283 PKKLfNRLEQLVVLDLSANKLKG-----------------------DHIEAETFgGLIRLIVLDLSHNAFTGVAQNMFKD 339
Cdd:PLN00113   229 PYEI-GGLTSLNHLDLVYNNLTGpipsslgnlknlqylflyqnklsGPIPPSIF-SLQKLISLDLSDNSLSGEIPELVIQ 306
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  340 LFFLQILNL-SNNSIGFIEDnAFSPLFNLHTLNLAVNKlrtiedhvFNGLfilnklnlnnnilsyVAENAFRNcSDLKEL 418
Cdd:PLN00113   307 LQNLEILHLfSNNFTGKIPV-ALTSLPRLQVLQLWSNK--------FSGE---------------IPKNLGKH-NNLTVL 361
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  419 DLSSNKLT-KVPEAILQLPFLKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQI-GNLTSGM----------------- 479
Cdd:PLN00113   362 DLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFsGELPSEFtklplvyfldisnnnlq 441
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696  480 ------FWGLPSLQVLNLAKNKIqSIETETFQRNVQLEAVRLDGNFISD-INGVFVSLTKLLWLNLSENHL 543
Cdd:PLN00113   442 grinsrKWDMPSLQMLSLARNKF-FGGLPDSFGSKRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSENKL 511
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
167-353 6.92e-15

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 75.21  E-value: 6.92e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  167 LENIISLNLTRNKIKFVDELgfgHKCGStLQTIDLSYNDIMSLPAdseILHLRRLTQLFLQNNKISELPGevFSDLLSLK 246
Cdd:cd21340      1 LKRITHLYLNDKNITKIDNL---SLCKN-LKVLYLYDNKITKIEN---LEFLTNLTHLYLQNNQIEKIEN--LENLVNLK 71
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  247 VVNLSENAINYLpEGLfQNTREIREIYLSY------NELEIMPKKLFNRLEQLVVLDLSANKLKgdhiEAETFGGLIRLI 320
Cdd:cd21340     72 KLYLGGNRISVV-EGL-ENLTNLEELHIENqrlppgEKLTFDPRSLAALSNSLRVLNISGNNID----SLEPLAPLRNLE 145
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2207073696  321 VLDLSHNAFTGVAQ--NMFKDLFFLQILNLSNNSI 353
Cdd:cd21340    146 QLDASNNQISDLEEllDLLSSWPSLRELDLTGNPV 180
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
218-442 3.71e-14

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 72.90  E-value: 3.71e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  218 LRRLTQLFLQNNKISELpgEVFSDLLSLKVVNLSENAINYLpEGLFQNTReIREIYLSYNELEIMPKklFNRLEQLVVLD 297
Cdd:cd21340      1 LKRITHLYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKI-ENLEFLTN-LTHLYLQNNQIEKIEN--LENLVNLKKLY 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  298 LSANKLKgdHIEAetFGGLIRLIVLDLSHnaftgvaQNMFKD--LFF-----------LQILNLSNNSIGFIEDnaFSPL 364
Cdd:cd21340     75 LGGNRIS--VVEG--LENLTNLEELHIEN-------QRLPPGekLTFdprslaalsnsLRVLNISGNNIDSLEP--LAPL 141
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  365 FNLHTLNLAVNKLRTIEDhvfnglfilnklnlnnnilsyvAENAFRNCSDLKELDLSSNKLTKVP----EAILQLPFLKS 440
Cdd:cd21340    142 RNLEQLDASNNQISDLEE----------------------LLDLLSSWPSLRELDLTGNPVCKKPkyrdKIILASKSLEV 199

                   ..
gi 2207073696  441 LD 442
Cdd:cd21340    200 LD 201
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
97-566 7.70e-13

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 73.34  E-value: 7.70e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696   97 SDCKILRLPGNVFEG--------LRGLKTLKLRSmnNQWghNKELDLSLGAfngLRELHTLDLGYNNIR-KIPSDLfCAL 167
Cdd:PLN00113   164 SSLKVLDLGGNVLVGkipnsltnLTSLEFLTLAS--NQL--VGQIPRELGQ---MKSLKWIYLGYNNLSgEIPYEI-GGL 235
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  168 ENIISLNLTRNKIKFVDELGFGHKcgSTLQTIDLsYNDIMSLPADSEILHLRRLTQLFLQNNKIS-ELPgEVFSDLLSLK 246
Cdd:PLN00113   236 TSLNHLDLVYNNLTGPIPSSLGNL--KNLQYLFL-YQNKLSGPIPPSIFSLQKLISLDLSDNSLSgEIP-ELVIQLQNLE 311
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  247 VVNL-SENAINYLPEGLFQNTReIREIYLSYNEL--EImPKKLFNRlEQLVVLDLSANKLKGDHIEAE-TFGGLIRLIVL 322
Cdd:PLN00113   312 ILHLfSNNFTGKIPVALTSLPR-LQVLQLWSNKFsgEI-PKNLGKH-NNLTVLDLSTNNLTGEIPEGLcSSGNLFKLILF 388
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  323 D---------------------LSHNAFTGVAQNMFKDLFFLQILNLSNNSI-GFIEDNAFSpLFNLHTLNLAVNKlrti 380
Cdd:PLN00113   389 SnslegeipkslgacrslrrvrLQDNSFSGELPSEFTKLPLVYFLDISNNNLqGRINSRKWD-MPSLQMLSLARNK---- 463
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  381 edhvFNGLFilnklnlnnnilsyvaENAFRNcSDLKELDLSSNKLTK-VPEAILQLPFLKSLDLGENLLTEISNNSFQNL 459
Cdd:PLN00113   464 ----FFGGL----------------PDSFGS-KRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSENKLSGEIPDELSSC 522
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  460 SQLTGLRLIDNQIGNLTSGMFWGLPSLQVLNLAKNkiqsietetfqrnvqleavRLDGNFISDINGVfvslTKLLWLNLS 539
Cdd:PLN00113   523 KKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQN-------------------QLSGEIPKNLGNV----ESLVQVNIS 579
                          490       500
                   ....*....|....*....|....*..
gi 2207073696  540 ENHLvwfdYAFIPPGLKWLDIHANFIE 566
Cdd:PLN00113   580 HNHL----HGSLPSTGAFLAINASAVA 602
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
194-636 6.55e-12

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 70.26  E-value: 6.55e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  194 STLQTIDLSYNDImSLPADSEILHLRRLTQLFLQNNKIS-ELPGEVFSDLLSLKVVNLSENAIN-YLPEGLFQNtreIRE 271
Cdd:PLN00113    69 SRVVSIDLSGKNI-SGKISSAIFRLPYIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTgSIPRGSIPN---LET 144
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  272 IYLSYNELEIMPKKLFNRLEQLVVLDLSANKLKGdHIEAeTFGGLIRLIVLDLSHNAFTG-----VAQNMFKDLFFLQIL 346
Cdd:PLN00113   145 LDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVG-KIPN-SLTNLTSLEFLTLASNQLVGqipreLGQMKSLKWIYLGYN 222
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  347 NLS--------------------NNSIGFIEdNAFSPLFNLHTLNLAVNKLR-TIEDHVFNGLFILNKLNLNNNILSYVA 405
Cdd:PLN00113   223 NLSgeipyeiggltslnhldlvyNNLTGPIP-SSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSGEIP 301
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  406 ENAFRnCSDLKELDLSSNKLT-KVPEAILQLPFLKSLDLGENLLT-EISnnsfQNLSQLTGLRLIDNQIGNLTSGMFWGL 483
Cdd:PLN00113   302 ELVIQ-LQNLEILHLFSNNFTgKIPVALTSLPRLQVLQLWSNKFSgEIP----KNLGKHNNLTVLDLSTNNLTGEIPEGL 376
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  484 PS---LQVLNLAKNKIQSIETETFQRNVQLEAVRL-DGNFISDINGVFVSLTKLLWLNLSENHLVWF--DYAFIPPGLKW 557
Cdd:PLN00113   377 CSsgnLFKLILFSNSLEGEIPKSLGACRSLRRVRLqDNSFSGELPSEFTKLPLVYFLDISNNNLQGRinSRKWDMPSLQM 456
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  558 LDIHANfiEVLGNYYKIQNNLNVKTLDASHNRI---VTLNKMSIPNSVELLfINNNFISSIEPDSFLEKNNLTRVDMYAN 634
Cdd:PLN00113   457 LSLARN--KFFGGLPDSFGSKRLENLDLSRNQFsgaVPRKLGSLSELMQLK-LSENKLSGEIPDELSSCKKLVSLDLSHN 533

                   ..
gi 2207073696  635 EI 636
Cdd:PLN00113   534 QL 535
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
96-454 5.11e-11

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 67.18  E-value: 5.11e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696   96 LSDCKILRLPGNVFEG-----LRGLKTLKLRSM--NNQWGhnkELDLSLGafnGLRELHTLDLGYNNIR-KIPSDLfCAL 167
Cdd:PLN00113   187 LTSLEFLTLASNQLVGqipreLGQMKSLKWIYLgyNNLSG---EIPYEIG---GLTSLNHLDLVYNNLTgPIPSSL-GNL 259
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  168 ENIISLNLTRNKIKF-VDELGFGHKcgsTLQTIDLSYN----DIMSLPA---DSEILHL----------------RRLTQ 223
Cdd:PLN00113   260 KNLQYLFLYQNKLSGpIPPSIFSLQ---KLISLDLSDNslsgEIPELVIqlqNLEILHLfsnnftgkipvaltslPRLQV 336
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  224 LFLQNNKISelpGEVFSDL---LSLKVVNLSENAIN-YLPEGLFQNTREIREIYLSyNELEIMPKKLFNRLEQLVVLDLS 299
Cdd:PLN00113   337 LQLWSNKFS---GEIPKNLgkhNNLTVLDLSTNNLTgEIPEGLCSSGNLFKLILFS-NSLEGEIPKSLGACRSLRRVRLQ 412
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  300 ANKLKGDHieAETFGGLIRLIVLDLSHNAFTGVAQNMFKDLFFLQILNLSNNSI-GFIEDNAFSPlfNLHTLNLAVNKLR 378
Cdd:PLN00113   413 DNSFSGEL--PSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFfGGLPDSFGSK--RLENLDLSRNQFS 488
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696  379 TIEDHVFNGLFILNKLNLNNNILSYVAENAFRNCSDLKELDLSSNKLT-KVPEAILQLPFLKSLDLGENLLT-EISNN 454
Cdd:PLN00113   489 GAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKN 566
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
804-904 3.57e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 61.34  E-value: 3.57e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  804 LYLNSSSVNNIKNetFRSLNDLRILHLDDNKIRYLRGLEFskLSNLKELYLQNNVIEFISNdsFSFLLALEVLRLDGNRL 883
Cdd:cd21340      7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIENLEF--LTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI 80
                           90       100
                   ....*....|....*....|.
gi 2207073696  884 VNygLWHLDNNKKLQTLFVGN 904
Cdd:cd21340     81 SV--VEGLENLTNLEELHIEN 99
TIR_2 pfam13676
TIR domain; This is a family of Toll-like receptors.
1029-1137 4.15e-10

TIR domain; This is a family of Toll-like receptors.


Pssm-ID: 463954 [Multi-domain]  Cd Length: 118  Bit Score: 58.48  E-value: 4.15e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 1029 YICYSPKDEEFViESLARELE-NGYpsyHLCLHYRDVPqfeaTYAQFPDLVVEATEASRRIIVVLSKNFILTEWSQVEFR 1107
Cdd:pfam13676    2 FISYAGEDRAWA-EWLADALEaAGY---RVWLDRWDIR----PGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWE 73
                           90       100       110
                   ....*....|....*....|....*....|
gi 2207073696 1108 QALQRALRKNphKLIIVAVGLVARDPELKS 1137
Cdd:pfam13676   74 AALADPEGRK--RLIPVRLECDLELPGLAG 101
LRR_8 pfam13855
Leucine rich repeat;
825-883 7.15e-10

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 55.99  E-value: 7.15e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696  825 LRILHLDDNKIRYLRGLEFSKLSNLKELYLQNNVIEFISNDSFSFLLALEVLRLDGNRL 883
Cdd:pfam13855    3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
318-654 7.59e-10

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 63.71  E-value: 7.59e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  318 RLIVLDLSHNAFTGVAQNMFKDLFFLQILNLSNNSI-GFIEDNAFSPLFNLHTLNLAVNKlrtiedhvFNGLFILNKLnl 396
Cdd:PLN00113    70 RVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLsGPIPDDIFTTSSSLRYLNLSNNN--------FTGSIPRGSI-- 139
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  397 nnnilsyvaenafrncSDLKELDLSSNKLT-KVPEAILQLPFLKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQI--- 472
Cdd:PLN00113   140 ----------------PNLETLDLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLvgq 203
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  473 ------------------GNLTSGM---FWGLPSLQVLNLAKNKIQSIETETFQRNVQLEAVRLDGNFISD-INGVFVSL 530
Cdd:PLN00113   204 iprelgqmkslkwiylgyNNLSGEIpyeIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGpIPPSIFSL 283
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  531 TKLLWLNLSENHLVwfdyAFIPPglkwLDIHANFIEVLgnyYKIQNNLNVKTLDA--SHNRIVTL----NKMS--IP--- 599
Cdd:PLN00113   284 QKLISLDLSDNSLS----GEIPE----LVIQLQNLEIL---HLFSNNFTGKIPVAltSLPRLQVLqlwsNKFSgeIPknl 352
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2207073696  600 ---NSVELLFINNNFISSIEPDSFLEKNNLTRVDMYANEIE-----SL-DINSLRISRVDEQAL 654
Cdd:PLN00113   353 gkhNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEgeipkSLgACRSLRRVRLQDNSF 416
LRR_8 pfam13855
Leucine rich repeat;
219-279 2.73e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 54.45  E-value: 2.73e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696  219 RRLTQLFLQNNKISELPGEVFSDLLSLKVVNLSENAINYLPEGLFQNTREIREIYLSYNEL 279
Cdd:pfam13855    1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
146-353 2.75e-09

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 61.64  E-value: 2.75e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  146 LHTLDLGYNNIRKIPSDLfcaLENIISLNLTRNKIKFVDElgfghKCGSTLQTIDLSYNDIMSLPaDSEILHLRRLTqlf 225
Cdd:PRK15370   222 IKTLYANSNQLTSIPATL---PDTIQEMELSINRITELPE-----RLPSALQSLDLFHNKISCLP-ENLPEELRYLS--- 289
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  226 LQNNKISELPGEVFSDLLSLKVVNlseNAINYLPEGLFQNtreIREIYLSYNELEIMPKKLFNRLEqlvVLDLSANKLKg 305
Cdd:PRK15370   290 VYDNSIRTLPAHLPSGITHLNVQS---NSLTALPETLPPG---LKTLEAGENALTSLPASLPPELQ---VLDVSKNQIT- 359
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2207073696  306 dhIEAETFGGLIRliVLDLSHNAFTGVAQNMFKDlffLQILNLSNNSI 353
Cdd:PRK15370   360 --VLPETLPPTIT--TLDVSRNALTNLPENLPAA---LQIMQASRNNL 400
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
222-462 5.81e-09

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 60.48  E-value: 5.81e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  222 TQLFLQNNKISELPGEVFSDLLSLKvvnLSENAINYLPEGLFQNtreIREIYLSYNELEIMPKKLFNRLEqlvVLDLSAN 301
Cdd:PRK15370   181 TELRLKILGLTTIPACIPEQITTLI---LDNNELKSLPENLQGN---IKTLYANSNQLTSIPATLPDTIQ---EMELSIN 251
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  302 KLKG--DHIEAEtfgglirLIVLDLSHNAFTGVAQNMFKDlffLQILNLSNNSIGFIEDNAFSPLFNLHTLNlavNKLRT 379
Cdd:PRK15370   252 RITElpERLPSA-------LQSLDLFHNKISCLPENLPEE---LRYLSVYDNSIRTLPAHLPSGITHLNVQS---NSLTA 318
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  380 IEDHVFNGLFILNklnlnnnilsyVAENAFRNC-----SDLKELDLSSNKLTKVPEAIlqLPFLKSLDLGENLLTEISNN 454
Cdd:PRK15370   319 LPETLPPGLKTLE-----------AGENALTSLpaslpPELQVLDVSKNQITVLPETL--PPTITTLDVSRNALTNLPEN 385
                          250
                   ....*....|....*...
gi 2207073696  455 ----------SFQNLSQL 462
Cdd:PRK15370   386 lpaalqimqaSRNNLVRL 403
LRR_8 pfam13855
Leucine rich repeat;
438-496 1.21e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 52.53  E-value: 1.21e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696  438 LKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQIGNLTSGMFWGLPSLQVLNLAKNKI 496
Cdd:pfam13855    3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
415-472 2.11e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.76  E-value: 2.11e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696  415 LKELDLSSNKLTKV-PEAILQLPFLKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQI 472
Cdd:pfam13855    3 LRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
292-353 2.13e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.76  E-value: 2.13e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2207073696  292 QLVVLDLSANKLKgdHIEAETFGGLIRLIVLDLSHNAFTGVAQNMFKDLFFLQILNLSNNSI 353
Cdd:pfam13855    2 NLRSLDLSNNRLT--SLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
778-905 2.53e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 57.64  E-value: 2.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  778 THIYLDGNNYNVLNESVFNsMHKAMVLYLNSSSVNNIkNETFRSLNDLRILHLDDNKIRYLrGLEFSKLSNLKELYLQNN 857
Cdd:COG4886    116 ESLDLSGNQLTDLPEELAN-LTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNN 192
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2207073696  858 VIEFISnDSFSFLLALEVLRLDGNRLVNYGLWhLDNNKKLQTLFVGNN 905
Cdd:COG4886    193 QITDLP-EPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNN 238
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
1026-1160 3.31e-08

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 54.29  E-value: 3.31e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 1026 YDAYICYSPKDEE--FVIESLARELENGYpsyHLCLHYRDVPQFEAtYAqfpDLVVEATEASRRIIVVLSKNFILTEWSQ 1103
Cdd:pfam01582    1 YDVFLSFRGSDTRewFVSHLLKELKQKGI---KLFIDDRDLEPGEA-IA---PELLSAIEKSRRSVVVLSPNYASSGWCL 73
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 1104 VEFRQALQRALRKNpHKLIIVAVGLVARD--------PELKSYFKTGLE----ITWK-----------------EKRFWE 1154
Cdd:pfam01582   74 DELVKILECALDLG-QKVIPIFYEVDPSDvrkqtgsfGKAFKKHKKVLTeekvLKWRgalnevaniwhsksvsdESKFWK 152

                   ....*.
gi 2207073696 1155 RLRYAM 1160
Cdd:pfam01582  153 KIAYDI 158
LRR_8 pfam13855
Leucine rich repeat;
318-377 1.99e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.06  E-value: 1.99e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  318 RLIVLDLSHNAFTGVAQNMFKDLFFLQILNLSNNSIGFIEDNAFSPLFNLHTLNLAVNKL 377
Cdd:pfam13855    2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
802-859 2.86e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.67  E-value: 2.86e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696  802 MVLYLNSSSVNNIKNETFRSLNDLRILHLDDNKIRYLRGLEFSKLSNLKELYLQNNVI 859
Cdd:pfam13855    4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
484-543 5.20e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 47.90  E-value: 5.20e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696  484 PSLQVLNLAKNKIQSIETETFQRNVQLEAVRLDGNFISDIN-GVFVSLTKLLWLNLSENHL 543
Cdd:pfam13855    1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSpGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
291-496 1.08e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 51.97  E-value: 1.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  291 EQLVVLDLSANKLKGD----HIEAETFGGLIRLIVLDLSHNAFTGVAQNMFKDL---FFLQILNLSNNSIG-----FIED 358
Cdd:cd00116     51 PSLKELCLSLNETGRIprglQSLLQGLTKGCGLQELDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLGdrglrLLAK 130
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  359 ----------------------------NAFSPLFNLHTLNLAVNKLRtiedhvfnglfilnklnlnNNILSYVAEnAFR 410
Cdd:cd00116    131 glkdlppaleklvlgrnrlegascealaKALRANRDLKELNLANNGIG-------------------DAGIRALAE-GLK 190
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  411 NCSDLKELDLSSNKLT-----KVPEAILQLPFLKSLDLGENLLT-----EISNNSFQNLSQLTGLRLIDNQIGNLTSGMF 480
Cdd:cd00116    191 ANCNLEVLDLNNNGLTdegasALAETLASLKSLEVLNLGDNNLTdagaaALASALLSPNISLLTLSLSCNDITDDGAKDL 270
                          250       260
                   ....*....|....*....|
gi 2207073696  481 WGL----PSLQVLNLAKNKI 496
Cdd:cd00116    271 AEVlaekESLLELDLRGNKF 290
LRR_8 pfam13855
Leucine rich repeat;
460-518 1.27e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 46.75  E-value: 1.27e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696  460 SQLTGLRLIDNQIGNLTSGMFWGLPSLQVLNLAKNKIQSIETETFQRNVQLEAVRLDGN 518
Cdd:pfam13855    1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
83-329 1.40e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 51.59  E-value: 1.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696   83 HYFGKMQGLTEITLSDCKILRLPGNVFEGLRGLKTLKLRSMNNqwghnkeldlslgafNGLRELHTLDLGynnirKIPSD 162
Cdd:cd00116     75 QGLTKGCGLQELDLSDNALGPDGCGVLESLLRSSSLQELKLNN---------------NGLGDRGLRLLA-----KGLKD 134
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  163 LFCALEniiSLNLTRNKIKF--VDELGFGHKCGSTLQTIDLSYNDIMS--LPADSEIL-HLRRLTQLFLQNNKISELPG- 236
Cdd:cd00116    135 LPPALE---KLVLGRNRLEGasCEALAKALRANRDLKELNLANNGIGDagIRALAEGLkANCNLEVLDLNNNGLTDEGAs 211
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  237 ---EVFSDLLSLKVVNLSENAIN-----YLPEGLFQNTREIREIYLSYNELEIMPKKLFNRL----EQLVVLDLSANKLK 304
Cdd:cd00116    212 alaETLASLKSLEVLNLGDNNLTdagaaALASALLSPNISLLTLSLSCNDITDDGAKDLAEVlaekESLLELDLRGNKFG 291
                          250       260
                   ....*....|....*....|....*...
gi 2207073696  305 --GDHIEAETFGGLI-RLIVLDLSHNAF 329
Cdd:cd00116    292 eeGAQLLAESLLEPGnELESLWVKDDSF 319
LRR_8 pfam13855
Leucine rich repeat;
267-327 3.10e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.59  E-value: 3.10e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696  267 REIREIYLSYNELEIMPKKLFNRLEQLVVLDLSANKLKgdHIEAETFGGLIRLIVLDLSHN 327
Cdd:pfam13855    1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT--TLSPGAFSGLPSLRYLDLSGN 59
LRR_8 pfam13855
Leucine rich repeat;
144-206 4.77e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.21  E-value: 4.77e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2207073696  144 RELHTLDLGYNNIRKIPSDLFCALENIISLNLTRNKIKFVDELGFGHkCGStLQTIDLSYNDI 206
Cdd:pfam13855    1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSG-LPS-LRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
220-427 8.16e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 49.28  E-value: 8.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  220 RLTQLFLQNNKISELPGEVFSDLL---SLKVVNLSENAIN-----YLPEGLFQNTREIREIYLSYNELEIMP----KKLF 287
Cdd:cd00116     82 GLQELDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGdrglrLLAKGLKDLPPALEKLVLGRNRLEGAScealAKAL 161
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  288 NRLEQLVVLDLSANKLKGDHIE--AETFGGLIRLIVLDLSHNAFT--GVAQ--NMFKDLFFLQILNLSNNSIGF-----I 356
Cdd:cd00116    162 RANRDLKELNLANNGIGDAGIRalAEGLKANCNLEVLDLNNNGLTdeGASAlaETLASLKSLEVLNLGDNNLTDagaaaL 241
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696  357 EDNAFSPLFNLHTLNLAVNKlrtIEDHVFnglfilnklnlnNNILSYVAENafrncSDLKELDLSSNKLTK 427
Cdd:cd00116    242 ASALLSPNISLLTLSLSCND---ITDDGA------------KDLAEVLAEK-----ESLLELDLRGNKFGE 292
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
131-286 2.16e-05

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 48.92  E-value: 2.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  131 KELDLSLGAFNGL-----RELHTLDLGYNNIRKIPSDLfcaLENIISLNLTRNKIKFVDE-LGFGhkcgstLQTIDLSYN 204
Cdd:PRK15370   265 QSLDLFHNKISCLpenlpEELRYLSVYDNSIRTLPAHL---PSGITHLNVQSNSLTALPEtLPPG------LKTLEAGEN 335
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  205 DIMSLPADSEilhlRRLTQLFLQNNKISELPGEVFSDLLSLKVvnlSENAINYLPEGLfqnTREIREIYLSYNELEIMPK 284
Cdd:PRK15370   336 ALTSLPASLP----PELQVLDVSKNQITVLPETLPPTITTLDV---SRNALTNLPENL---PAALQIMQASRNNLVRLPE 405

                   ..
gi 2207073696  285 KL 286
Cdd:PRK15370   406 SL 407
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
418-636 2.85e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 46.70  E-value: 2.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  418 LDLSSNKLTKVpEAILQLPFLKSLDLGENLLTEISNnsFQNLSQLTGLRLIDNQI---GNLTSgmfwgLPSLQVLNLAKN 494
Cdd:cd21340      7 LYLNDKNITKI-DNLSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIekiENLEN-----LVNLKKLYLGGN 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  495 KIQSIEtetfqrnvQLEavrldgnfisdingvfvSLTKLLWLNLSENHLvwfdyafiPPGLKwLDIHANFIEVLGNyyki 574
Cdd:cd21340     79 RISVVE--------GLE-----------------NLTNLEELHIENQRL--------PPGEK-LTFDPRSLAALSN---- 120
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2207073696  575 qnnlNVKTLDASHNRIVTLNKMSIPNSVELLFINNNFISSIEPDSFLEKN--NLTRVDMYANEI 636
Cdd:cd21340    121 ----SLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEELLDLLSSwpSLRELDLTGNPV 180
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
140-255 3.10e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 46.70  E-value: 3.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  140 FNGLRELHTLDLGYNNIRKIpSDLFCaLENIISLNLTRNKIKFVDELGFGHKC----GSTLQTIDLSYNDIMSLpadSEI 215
Cdd:cd21340     64 LENLVNLKKLYLGGNRISVV-EGLEN-LTNLEELHIENQRLPPGEKLTFDPRSlaalSNSLRVLNISGNNIDSL---EPL 138
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 2207073696  216 LHLRRLTQLFLQNNKISELP--GEVFSDLLSLKVVNLSENAI 255
Cdd:cd21340    139 APLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
113-180 3.79e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.51  E-value: 3.79e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696  113 RGLKTLKLRsmnnqwgHNKELDLSLGAFNGLRELHTLDLGYNNIRKIPSDLFCALENIISLNLTRNKI 180
Cdd:pfam13855    1 PNLRSLDLS-------NNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
89-156 3.90e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.51  E-value: 3.90e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696   89 QGLTEITLSDCKILRLPGNVFEGLRGLKTLKLrsmnnqwGHNKELDLSLGAFNGLRELHTLDLGYNNI 156
Cdd:pfam13855    1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDL-------SNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
289-353 4.13e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 47.89  E-value: 4.13e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2207073696  289 RLEQLVVLDLSANKLKGDhIEAeTFGGLIRLIVLDLSHNAFTGVAQNMFKDLFFLQILNLSNNSI 353
Cdd:PLN03150   440 KLRHLQSINLSGNSIRGN-IPP-SLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
125-378 4.63e-05

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 47.48  E-value: 4.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  125 NQWGHNKELDLSLGAFNGLRELHTLDLGYNNIrkipsdlfcALENIISL--NLTRNKikfvdelgfghkcgsTLQTIDLS 202
Cdd:COG5238    161 LAARLGLLAAISMAKALQNNSVETVYLGCNQI---------GDEGIEELaeALTQNT---------------TVTTLWLK 216
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  203 YNDIMSLPADSEILHLR---RLTQLFLQNNKISELPGEVFSDLL----SLKVVNLSENAIN-----YLPEGLFQNTrEIR 270
Cdd:COG5238    217 RNPIGDEGAEILAEALKgnkSLTTLDLSNNQIGDEGVIALAEALknntTVETLYLSGNQIGaegaiALAKALQGNT-TLT 295
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  271 EIYLSYNEL-EIMPKKLFNRLEQ---LVVLDLSANKLKGDHIE--AETFGGLIRLIVLDLSHNAFT-----GVAQNMfKD 339
Cdd:COG5238    296 SLDLSVNRIgDEGAIALAEGLQGnktLHTLNLAYNGIGAQGAIalAKALQENTTLHSLDLSDNQIGdegaiALAKYL-EG 374
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2207073696  340 LFFLQILNLSNNSI---GFIEDNAFSPLFNLHTLNLAVNKLR 378
Cdd:COG5238    375 NTTLRELNLGKNNIgkqGAEALIDALQTNRLHTLILDGNLIG 416
LRR_8 pfam13855
Leucine rich repeat;
343-425 4.79e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.13  E-value: 4.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  343 LQILNLSNNSIGFIEDNAFSPLFNLHTLNLAVNKLRTIEDHvfnglfilnklnlnnnilsyvaenAFRNCSDLKELDLSS 422
Cdd:pfam13855    3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPG------------------------AFSGLPSLRYLDLSG 58

                   ...
gi 2207073696  423 NKL 425
Cdd:pfam13855   59 NRL 61
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
351-463 6.74e-05

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 43.69  E-value: 6.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  351 NSIGFIEDNAFSPLFNLHTLNLAvNKLRTIEDHVFNGLFILNKLNLNNNilSYVAENAFRNCSDLKELDLSSNkLTKVPE 430
Cdd:pfam13306   20 SSLTSIGEYAFSNCTSLKSITLP-SSLTSIGSYAFYNCSLTSITIPSSL--TSIGEYAFSNCSNLKSITLPSN-LTSIGS 95
                           90       100       110
                   ....*....|....*....|....*....|...
gi 2207073696  431 AILQLPFLKSLDLGENlLTEISNNSFQNLSQLT 463
Cdd:pfam13306   96 YAFSNCSLKSITIPSS-VTTIGSYAFSNCSNLK 127
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
778-904 7.16e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 45.55  E-value: 7.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  778 THIYLDGNNYNVLNEsvFNSMHKAMVLYLNSSSVNNIKN--------------------ETFRSLNDLRILHLDDNKIRY 837
Cdd:cd21340      5 THLYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIENlefltnlthlylqnnqiekiENLENLVNLKKLYLGGNRISV 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  838 LRGLEfsKLSNLKELYLQN------NVIEF----------------ISN------DSFSFLLALEVLRLDGNRLVNYG-- 887
Cdd:cd21340     83 VEGLE--NLTNLEELHIENqrlppgEKLTFdprslaalsnslrvlnISGnnidslEPLAPLRNLEQLDASNNQISDLEel 160
                          170
                   ....*....|....*...
gi 2207073696  888 LWHLDNNKKLQTL-FVGN 904
Cdd:cd21340    161 LDLLSSWPSLRELdLTGN 178
LRR_8 pfam13855
Leucine rich repeat;
778-835 8.15e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.74  E-value: 8.15e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696  778 THIYLDGNNYNVLNESVFNSMHKAMVLYLNSSSVNNIKNETFRSLNDLRILHLDDNKI 835
Cdd:pfam13855    4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
194-255 1.29e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.97  E-value: 1.29e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2207073696  194 STLQTIDLSYNDIMSLPADSeILHLRRLTQLFLQNNKISELPGEVFSDLLSLKVVNLSENAI 255
Cdd:pfam13855    1 PNLRSLDLSNNRLTSLDDGA-FKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRRNT smart00013
Leucine rich repeat N-terminal domain;
742-779 2.02e-04

Leucine rich repeat N-terminal domain;


Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 39.61  E-value: 2.02e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 2207073696   742 CPNNCSCyHDStkttnVVDCSVKQLDAVPRDFPNGATH 779
Cdd:smart00013    2 CPAPCNC-SGT-----AVDCSGRGLTEVPLDLPPDTTL 33
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
244-522 2.25e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 45.17  E-value: 2.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  244 SLKVVNLSENAIN-----YLPEGLFQNTrEIREIYLSYNE-----LEIMPKKLfNRLEQLVVLDLSANKLK--GDHIEAE 311
Cdd:COG5238    181 SVETVYLGCNQIGdegieELAEALTQNT-TVTTLWLKRNPigdegAEILAEAL-KGNKSLTTLDLSNNQIGdeGVIALAE 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  312 TFGGLIRLIVLDLSHNAFT-----GVAQNmfkdlfflqilnLSNNSigfiednafsplfNLHTLNLAVNKLRtiedhvfn 386
Cdd:COG5238    259 ALKNNTTVETLYLSGNQIGaegaiALAKA------------LQGNT-------------TLTSLDLSVNRIG-------- 305
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  387 glfilnklnlnnnILSYVA-ENAFRNCSDLKELDLSSNKLTKVpEAILqlpflksldLGENLlteisnnsfQNLSQLTGL 465
Cdd:COG5238    306 -------------DEGAIAlAEGLQGNKTLHTLNLAYNGIGAQ-GAIA---------LAKAL---------QENTTLHSL 353
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2207073696  466 RLIDNQIGNltSGM------FWGLPSLQVLNLAKNKIQSIETETF----QRNvQLEAVRLDGNFISD 522
Cdd:COG5238    354 DLSDNQIGD--EGAialakyLEGNTTLRELNLGKNNIGKQGAEALidalQTN-RLHTLILDGNLIGA 417
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
408-543 4.01e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 43.88  E-value: 4.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  408 AFRNCSDLKELDLSSNKLTK----VPEAILQLPFLKSLDLGENLL----TEISNNSFQNLS-QLTGLRLIDNQIGNL--- 475
Cdd:cd00116     76 GLTKGCGLQELDLSDNALGPdgcgVLESLLRSSSLQELKLNNNGLgdrgLRLLAKGLKDLPpALEKLVLGRNRLEGAsce 155
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696  476 -TSGMFWGLPSLQVLNLAKNKI--QSIET--ETFQRNVQLEAVRLDGNFISDIN-----GVFVSLTKLLWLNLSENHL 543
Cdd:cd00116    156 aLAKALRANRDLKELNLANNGIgdAGIRAlaEGLKANCNLEVLDLNNNGLTDEGasalaETLASLKSLEVLNLGDNNL 233
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
817-905 4.08e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 43.88  E-value: 4.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  817 ETFRSLNDLRILHLDDNK-----IRYLrGLEFSKLSNLKELYLQNNVIE-----FISnDSFSFLLALEVLRLDGNRLVNY 886
Cdd:cd00116    159 KALRANRDLKELNLANNGigdagIRAL-AEGLKANCNLEVLDLNNNGLTdegasALA-ETLASLKSLEVLNLGDNNLTDA 236
                           90       100
                   ....*....|....*....|....
gi 2207073696  887 GLWHLDN-----NKKLQTLFVGNN 905
Cdd:cd00116    237 GAAALASallspNISLLTLSLSCN 260
LRR_8 pfam13855
Leucine rich repeat;
366-448 6.05e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.04  E-value: 6.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  366 NLHTLNLAVNKLRTIEDHvfnglfilnklnlnnnilsyvaenAFRNCSDLKELDLSSNKLTKV-PEAILQLPFLKSLDLG 444
Cdd:pfam13855    2 NLRSLDLSNNRLTSLDDG------------------------AFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLS 57

                   ....
gi 2207073696  445 ENLL 448
Cdd:pfam13855   58 GNRL 61
LRR_8 pfam13855
Leucine rich repeat;
847-905 7.30e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.04  E-value: 7.30e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696  847 SNLKELYLQNNVIEFISNDSFSFLLALEVLRLDGNRLVNYGLWHLDNNKKLQTLFVGNN 905
Cdd:pfam13855    1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
LRRNT pfam01462
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
742-774 8.27e-04

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 396168 [Multi-domain]  Cd Length: 28  Bit Score: 37.99  E-value: 8.27e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2207073696  742 CPNNCSCyHDStkttnVVDCSVKQLDAVPRDFP 774
Cdd:pfam01462    2 CPVPCHC-SAT-----VVNCSDRGLTAVPRDLP 28
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
732-905 1.65e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 42.23  E-value: 1.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  732 DFSFCNCKTVCPNNCSCYHDSTKTTNVVDCSVKQLDAVPRDFPNGATHIYLDGNNYNVLNESVFNSMHKAMVLYLNSSSV 811
Cdd:COG4886      5 LLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSL 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  812 NNIKNETFRSLNDLRILHLDDNKirylrglEFSKLSNLKELYLQNNVIEFISnDSFSFLLALEVLRLDGNRLVNYGLWhL 891
Cdd:COG4886     85 LLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLP-EELANLTNLKELDLSNNQLTDLPEP-L 155
                          170
                   ....*....|....
gi 2207073696  892 DNNKKLQTLFVGNN 905
Cdd:COG4886    156 GNLTNLKSLDLSNN 169
PLN03150 PLN03150
hypothetical protein; Provisional
159-254 1.90e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.50  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  159 IPSDLfCALENIISLNLTRNKIKFVDELGFGHKcgSTLQTIDLSYNDIMSLPADS--EILHLRRLTqlfLQNNKIS-ELP 235
Cdd:PLN03150   434 IPNDI-SKLRHLQSINLSGNSIRGNIPPSLGSI--TSLEVLDLSYNSFNGSIPESlgQLTSLRILN---LNGNSLSgRVP 507
                           90
                   ....*....|....*....
gi 2207073696  236 GEVFSDLLSLKVVNLSENA 254
Cdd:PLN03150   508 AALGGRLLHRASFNFTDNA 526
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
415-543 2.34e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 42.08  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  415 LKELDLSSNKLTKvPEAILQLPFLK------SLDLGENLLTEIS----NNSFQNLSQLTGLRLIDNQIGN-----LTSGM 479
Cdd:COG5238    238 LTTLDLSNNQIGD-EGVIALAEALKnnttveTLYLSGNQIGAEGaialAKALQGNTTLTSLDLSVNRIGDegaiaLAEGL 316
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2207073696  480 fWGLPSLQVLNLAKNKIQSIET----ETFQRNVQLEAVRLDGNFISDINGV-----FVSLTKLLWLNLSENHL 543
Cdd:COG5238    317 -QGNKTLHTLNLAYNGIGAQGAialaKALQENTTLHSLDLSDNQIGDEGAIalakyLEGNTTLRELNLGKNNI 388
LRRCT smart00082
Leucine rich repeat C-terminal domain;
662-719 5.01e-03

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 36.25  E-value: 5.01e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696   662 NPFRCDCTMKWLLLINsittREYPRVMDLENVICKESyvrGVKYLPVSSLHTKDFLCK 719
Cdd:smart00082    1 NPFICDCELRWLLRWL----QANEHLQDPVDLRCASP---SSLRGPLLELLHSEFKCP 51
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
45-243 6.40e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 40.54  E-value: 6.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696   45 NVRTLSSDRDVIGSmhsDGAERLAircgSHLLESTlkdhyfgkmqGLTEITLSDCKI----LRLPGNVFEGLRGLKTLKL 120
Cdd:COG5238    209 TVTTLWLKRNPIGD---EGAEILA----EALKGNK----------SLTTLDLSNNQIgdegVIALAEALKNNTTVETLYL 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  121 RSmnNQWGHN---------------KELDLSL------GAF---NGLRE---LHTLDLGYNNIRK---IPsdLFCALE-- 168
Cdd:COG5238    272 SG--NQIGAEgaialakalqgnttlTSLDLSVnrigdeGAIalaEGLQGnktLHTLNLAYNGIGAqgaIA--LAKALQen 347
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  169 -NIISLNLTRNKI--KFVDELGFGHKCGSTLQTIDLSYNDIMSLPADSEILHLR--RLTQLFLQNNKISELPGEVFSDLL 243
Cdd:COG5238    348 tTLHSLDLSDNQIgdEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQtnRLHTLILDGNLIGAEAQQRLEQLL 427
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
778-905 7.38e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 40.30  E-value: 7.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696  778 THIYLDGNNYNVLNESVFNsMHKAMVLYLNSSSVNNIKNetFRSLNDLRILHLDDNKIRYLRglEFSKLSNLKELYLQNN 857
Cdd:COG4886    208 EELDLSGNQLTDLPEPLAN-LTNLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLP--PLANLTNLKTLDLSNN 282
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2207073696  858 VIEFISNDSFSFLLALEVLRLDGNRLVNYGLWHLDNNKKLQTLFVGNN 905
Cdd:COG4886    283 QLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLL 330
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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