|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
239-643 |
8.55e-26 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 111.56 E-value: 8.55e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 239 FSDLLSLKVVNLSENAINYLPEGLFQNTREIREIYLSYNELEIMPKKLFNRLEQLVVLDLSANKLKGDHIEAETFGGLIR 318
Cdd:COG4886 18 LELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 319 LIVLDLSHNaftgvaqNMFKDLFFLQILNLSNNSIGFIEDnAFSPLFNLHTLNLAVNKLRTIEDhvfnglfilnklnlnn 398
Cdd:COG4886 98 LTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPE---------------- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 399 nilsyvaenAFRNCSDLKELDLSSNKLTKVPEAILQLPFLKSLDLGENLLTEISnNSFQNLSQLTGLRLIDNQIGNLTSG 478
Cdd:COG4886 154 ---------PLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEP 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 479 MFwGLPSLQVLNLAKNKIQSIetETFQRNVQLEAVRLDGNFISDInGVFVSLTKLLWLNLSENHLVWFDYAFIPPGLKWL 558
Cdd:COG4886 224 LA-NLTNLETLDLSNNQLTDL--PELGNLTNLEELDLSNNQLTDL-PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLN 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 559 DIHANFIEVLGNYYKIQNNLNVKTLDASHNRIVTLNKMSIPNSVELLFINNNFISSIEPDSFLEKNNLTRVDMYANEIES 638
Cdd:COG4886 300 SLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATL 379
|
....*
gi 2207073696 639 LDINS 643
Cdd:COG4886 380 LTLAL 384
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
1026-1162 |
2.39e-22 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 94.31 E-value: 2.39e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 1026 YDAYICYSPKDeeFVIESLARELENGYPSYHLCLHYRDVPqfeaTYAQFPDLVVEATEASRRIIVVLSKNFILTEWSQVE 1105
Cdd:smart00255 2 YDVFISYSGKE--DVRNEFLSHLLEKLRGYGLCVFIDDFE----PGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDE 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2207073696 1106 FRQALQRALRKNPHKLIIVAVGLVARDP-ELKSYFKTGLEITW------KEKRFWERLRYAMPS 1162
Cdd:smart00255 76 LVAALENALEEGGLRVIPIFYEVIPSDVrKQPGKFRKVFKKNYlkwpedEKEQFWKKALYAVPS 139
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
128-543 |
2.05e-17 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 88.37 E-value: 2.05e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 128 GHNKELDLSLGAFnGLRELHTLDLGYNNIR-KIPSDLFCALENIISLNLTRNKIKFVDELGFghkcGSTLQTIDLSyNDI 206
Cdd:PLN00113 78 GKNISGKISSAIF-RLPYIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTGSIPRGS----IPNLETLDLS-NNM 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 207 MSLPADSEILHLRRLTQLFLQNNKIS-ELPGEVfSDLLSLKVVNLSENA-INYLPEGLFQnTREIREIYLSYNEL--EIm 282
Cdd:PLN00113 152 LSGEIPNDIGSFSSLKVLDLGGNVLVgKIPNSL-TNLTSLEFLTLASNQlVGQIPRELGQ-MKSLKWIYLGYNNLsgEI- 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 283 PKKLfNRLEQLVVLDLSANKLKG-----------------------DHIEAETFgGLIRLIVLDLSHNAFTGVAQNMFKD 339
Cdd:PLN00113 229 PYEI-GGLTSLNHLDLVYNNLTGpipsslgnlknlqylflyqnklsGPIPPSIF-SLQKLISLDLSDNSLSGEIPELVIQ 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 340 LFFLQILNL-SNNSIGFIEDnAFSPLFNLHTLNLAVNKlrtiedhvFNGLfilnklnlnnnilsyVAENAFRNcSDLKEL 418
Cdd:PLN00113 307 LQNLEILHLfSNNFTGKIPV-ALTSLPRLQVLQLWSNK--------FSGE---------------IPKNLGKH-NNLTVL 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 419 DLSSNKLT-KVPEAILQLPFLKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQI-GNLTSGM----------------- 479
Cdd:PLN00113 362 DLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFsGELPSEFtklplvyfldisnnnlq 441
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696 480 ------FWGLPSLQVLNLAKNKIqSIETETFQRNVQLEAVRLDGNFISD-INGVFVSLTKLLWLNLSENHL 543
Cdd:PLN00113 442 grinsrKWDMPSLQMLSLARNKF-FGGLPDSFGSKRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSENKL 511
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
167-353 |
6.92e-15 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 75.21 E-value: 6.92e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 167 LENIISLNLTRNKIKFVDELgfgHKCGStLQTIDLSYNDIMSLPAdseILHLRRLTQLFLQNNKISELPGevFSDLLSLK 246
Cdd:cd21340 1 LKRITHLYLNDKNITKIDNL---SLCKN-LKVLYLYDNKITKIEN---LEFLTNLTHLYLQNNQIEKIEN--LENLVNLK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 247 VVNLSENAINYLpEGLfQNTREIREIYLSY------NELEIMPKKLFNRLEQLVVLDLSANKLKgdhiEAETFGGLIRLI 320
Cdd:cd21340 72 KLYLGGNRISVV-EGL-ENLTNLEELHIENqrlppgEKLTFDPRSLAALSNSLRVLNISGNNID----SLEPLAPLRNLE 145
|
170 180 190
....*....|....*....|....*....|....*
gi 2207073696 321 VLDLSHNAFTGVAQ--NMFKDLFFLQILNLSNNSI 353
Cdd:cd21340 146 QLDASNNQISDLEEllDLLSSWPSLRELDLTGNPV 180
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
804-904 |
3.57e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 61.34 E-value: 3.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 804 LYLNSSSVNNIKNetFRSLNDLRILHLDDNKIRYLRGLEFskLSNLKELYLQNNVIEFISNdsFSFLLALEVLRLDGNRL 883
Cdd:cd21340 7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIENLEF--LTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI 80
|
90 100
....*....|....*....|.
gi 2207073696 884 VNygLWHLDNNKKLQTLFVGN 904
Cdd:cd21340 81 SV--VEGLENLTNLEELHIEN 99
|
|
| TIR_2 |
pfam13676 |
TIR domain; This is a family of Toll-like receptors. |
1029-1137 |
4.15e-10 |
|
TIR domain; This is a family of Toll-like receptors.
Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 58.48 E-value: 4.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 1029 YICYSPKDEEFViESLARELE-NGYpsyHLCLHYRDVPqfeaTYAQFPDLVVEATEASRRIIVVLSKNFILTEWSQVEFR 1107
Cdd:pfam13676 2 FISYAGEDRAWA-EWLADALEaAGY---RVWLDRWDIR----PGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWE 73
|
90 100 110
....*....|....*....|....*....|
gi 2207073696 1108 QALQRALRKNphKLIIVAVGLVARDPELKS 1137
Cdd:pfam13676 74 AALADPEGRK--RLIPVRLECDLELPGLAG 101
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
825-883 |
7.15e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 55.99 E-value: 7.15e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696 825 LRILHLDDNKIRYLRGLEFSKLSNLKELYLQNNVIEFISNDSFSFLLALEVLRLDGNRL 883
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
219-279 |
2.73e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 54.45 E-value: 2.73e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696 219 RRLTQLFLQNNKISELPGEVFSDLLSLKVVNLSENAINYLPEGLFQNTREIREIYLSYNEL 279
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
778-905 |
2.53e-08 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 57.64 E-value: 2.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 778 THIYLDGNNYNVLNESVFNsMHKAMVLYLNSSSVNNIkNETFRSLNDLRILHLDDNKIRYLrGLEFSKLSNLKELYLQNN 857
Cdd:COG4886 116 ESLDLSGNQLTDLPEELAN-LTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNN 192
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2207073696 858 VIEFISnDSFSFLLALEVLRLDGNRLVNYGLWhLDNNKKLQTLFVGNN 905
Cdd:COG4886 193 QITDLP-EPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNN 238
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
83-329 |
1.40e-06 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 51.59 E-value: 1.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 83 HYFGKMQGLTEITLSDCKILRLPGNVFEGLRGLKTLKLRSMNNqwghnkeldlslgafNGLRELHTLDLGynnirKIPSD 162
Cdd:cd00116 75 QGLTKGCGLQELDLSDNALGPDGCGVLESLLRSSSLQELKLNN---------------NGLGDRGLRLLA-----KGLKD 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 163 LFCALEniiSLNLTRNKIKF--VDELGFGHKCGSTLQTIDLSYNDIMS--LPADSEIL-HLRRLTQLFLQNNKISELPG- 236
Cdd:cd00116 135 LPPALE---KLVLGRNRLEGasCEALAKALRANRDLKELNLANNGIGDagIRALAEGLkANCNLEVLDLNNNGLTDEGAs 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 237 ---EVFSDLLSLKVVNLSENAIN-----YLPEGLFQNTREIREIYLSYNELEIMPKKLFNRL----EQLVVLDLSANKLK 304
Cdd:cd00116 212 alaETLASLKSLEVLNLGDNNLTdagaaALASALLSPNISLLTLSLSCNDITDDGAKDLAEVlaekESLLELDLRGNKFG 291
|
250 260
....*....|....*....|....*...
gi 2207073696 305 --GDHIEAETFGGLI-RLIVLDLSHNAF 329
Cdd:cd00116 292 eeGAQLLAESLLEPGnELESLWVKDDSF 319
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
144-206 |
4.77e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.21 E-value: 4.77e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2207073696 144 RELHTLDLGYNNIRKIPSDLFCALENIISLNLTRNKIKFVDELGFGHkCGStLQTIDLSYNDI 206
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSG-LPS-LRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
131-286 |
2.16e-05 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 48.92 E-value: 2.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 131 KELDLSLGAFNGL-----RELHTLDLGYNNIRKIPSDLfcaLENIISLNLTRNKIKFVDE-LGFGhkcgstLQTIDLSYN 204
Cdd:PRK15370 265 QSLDLFHNKISCLpenlpEELRYLSVYDNSIRTLPAHL---PSGITHLNVQSNSLTALPEtLPPG------LKTLEAGEN 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 205 DIMSLPADSEilhlRRLTQLFLQNNKISELPGEVFSDLLSLKVvnlSENAINYLPEGLfqnTREIREIYLSYNELEIMPK 284
Cdd:PRK15370 336 ALTSLPASLP----PELQVLDVSKNQITVLPETLPPTITTLDV---SRNALTNLPENL---PAALQIMQASRNNLVRLPE 405
|
..
gi 2207073696 285 KL 286
Cdd:PRK15370 406 SL 407
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
742-779 |
2.02e-04 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 39.61 E-value: 2.02e-04
10 20 30
....*....|....*....|....*....|....*...
gi 2207073696 742 CPNNCSCyHDStkttnVVDCSVKQLDAVPRDFPNGATH 779
Cdd:smart00013 2 CPAPCNC-SGT-----AVDCSGRGLTEVPLDLPPDTTL 33
|
|
| LRRNT |
pfam01462 |
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ... |
742-774 |
8.27e-04 |
|
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.
Pssm-ID: 396168 [Multi-domain] Cd Length: 28 Bit Score: 37.99 E-value: 8.27e-04
10 20 30
....*....|....*....|....*....|...
gi 2207073696 742 CPNNCSCyHDStkttnVVDCSVKQLDAVPRDFP 774
Cdd:pfam01462 2 CPVPCHC-SAT-----VVNCSDRGLTAVPRDLP 28
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
662-719 |
5.01e-03 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 36.25 E-value: 5.01e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696 662 NPFRCDCTMKWLLLINsittREYPRVMDLENVICKESyvrGVKYLPVSSLHTKDFLCK 719
Cdd:smart00082 1 NPFICDCELRWLLRWL----QANEHLQDPVDLRCASP---SSLRGPLLELLHSEFKCP 51
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
45-243 |
6.40e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 40.54 E-value: 6.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 45 NVRTLSSDRDVIGSmhsDGAERLAircgSHLLESTlkdhyfgkmqGLTEITLSDCKI----LRLPGNVFEGLRGLKTLKL 120
Cdd:COG5238 209 TVTTLWLKRNPIGD---EGAEILA----EALKGNK----------SLTTLDLSNNQIgdegVIALAEALKNNTTVETLYL 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 121 RSmnNQWGHN---------------KELDLSL------GAF---NGLRE---LHTLDLGYNNIRK---IPsdLFCALE-- 168
Cdd:COG5238 272 SG--NQIGAEgaialakalqgnttlTSLDLSVnrigdeGAIalaEGLQGnktLHTLNLAYNGIGAqgaIA--LAKALQen 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 169 -NIISLNLTRNKI--KFVDELGFGHKCGSTLQTIDLSYNDIMSLPADSEILHLR--RLTQLFLQNNKISELPGEVFSDLL 243
Cdd:COG5238 348 tTLHSLDLSDNQIgdEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQtnRLHTLILDGNLIGAEAQQRLEQLL 427
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
239-643 |
8.55e-26 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 111.56 E-value: 8.55e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 239 FSDLLSLKVVNLSENAINYLPEGLFQNTREIREIYLSYNELEIMPKKLFNRLEQLVVLDLSANKLKGDHIEAETFGGLIR 318
Cdd:COG4886 18 LELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 319 LIVLDLSHNaftgvaqNMFKDLFFLQILNLSNNSIGFIEDnAFSPLFNLHTLNLAVNKLRTIEDhvfnglfilnklnlnn 398
Cdd:COG4886 98 LTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPE---------------- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 399 nilsyvaenAFRNCSDLKELDLSSNKLTKVPEAILQLPFLKSLDLGENLLTEISnNSFQNLSQLTGLRLIDNQIGNLTSG 478
Cdd:COG4886 154 ---------PLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEP 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 479 MFwGLPSLQVLNLAKNKIQSIetETFQRNVQLEAVRLDGNFISDInGVFVSLTKLLWLNLSENHLVWFDYAFIPPGLKWL 558
Cdd:COG4886 224 LA-NLTNLETLDLSNNQLTDL--PELGNLTNLEELDLSNNQLTDL-PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLN 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 559 DIHANFIEVLGNYYKIQNNLNVKTLDASHNRIVTLNKMSIPNSVELLFINNNFISSIEPDSFLEKNNLTRVDMYANEIES 638
Cdd:COG4886 300 SLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATL 379
|
....*
gi 2207073696 639 LDINS 643
Cdd:COG4886 380 LTLAL 384
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
124-594 |
1.06e-24 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 108.48 E-value: 1.06e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 124 NNQWGHNKELDLSLGAFNGLRELHTLDLGYNNIRKIPSDLFCALENIISLNLTRNKIKFVDELGFGHKCGSTLQTIDLSY 203
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 204 NDIMSLPADSEILHLRRLTQLFLQNNkiselpgEVFSDLLSLKVVNLSENAINYLPEGLFQNTReIREIYLSYNELEIMP 283
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELANLTN-LKELDLSNNQLTDLP 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 284 KKLFNrLEQLVVLDLSANKLKGdhIEAEtFGGLIRLIVLDLSHNaftgvaqnmfkdlfflQILNLSNnsigfiednAFSP 363
Cdd:COG4886 153 EPLGN-LTNLKSLDLSNNQLTD--LPEE-LGNLTNLKELDLSNN----------------QITDLPE---------PLGN 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 364 LFNLHTLNLAVNKLRTIEDhvfnglfilnklnlnnnilsyvaenAFRNCSDLKELDLSSNKLTKVPEaILQLPFLKSLDL 443
Cdd:COG4886 204 LTNLEELDLSGNQLTDLPE-------------------------PLANLTNLETLDLSNNQLTDLPE-LGNLTNLEELDL 257
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 444 GENLLTEISNNSfqNLSQLTGLRLIDNQIGNLTSGMFWGLPSLQVLNLakNKIQSIETETFQRNVQLEAVRLDGNFISDI 523
Cdd:COG4886 258 SNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLL--LLLLLNLLELLILLLLLTTLLLLLLLLKGL 333
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696 524 NGVFVSLTKLLWLNLSENHLVWFDYAFIPPGLKWLDIHANFIEVLGNYYKIQNNLNVKTLDASHNRIVTLN 594
Cdd:COG4886 334 LVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLT 404
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
131-462 |
1.20e-23 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 105.40 E-value: 1.20e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 131 KELDLS-LGAFNGLRELHTLDLGYNNIRKIPSDLFcALENIISLNLTRNKIK-FVDELGfghKCgSTLQTIDLSYNDIMS 208
Cdd:COG4886 99 TELDLSgNEELSNLTNLESLDLSGNQLTDLPEELA-NLTNLKELDLSNNQLTdLPEPLG---NL-TNLKSLDLSNNQLTD 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 209 LPadSEILHLRRLTQLFLQNNKISELPgEVFSDLLSLKVVNLSENAINYLPEGLFQNTReIREIYLSYNELEIMPKklFN 288
Cdd:COG4886 174 LP--EELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEPLANLTN-LETLDLSNNQLTDLPE--LG 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 289 RLEQLVVLDLSANKLKgdhiEAETFGGLIRLIVLDLSHNAFTGVAqnmFKDLFFLQILNLSNNSIGFIEDNAFSPLFNLH 368
Cdd:COG4886 248 NLTNLEELDLSNNQLT----DLPPLANLTNLKTLDLSNNQLTDLK---LKELELLLGLNSLLLLLLLLNLLELLILLLLL 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 369 TLNLAVNKLRTIEDHVFNGLFILNKLNLNNNILSYVAENAFRNCSDLKELDLSSNKLTKVPEAILQLPFLKSLDLGENLL 448
Cdd:COG4886 321 TTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGV 400
|
330
....*....|....
gi 2207073696 449 TEISNNSFQNLSQL 462
Cdd:COG4886 401 LLLTLALLDAVNTE 414
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
1026-1162 |
2.39e-22 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 94.31 E-value: 2.39e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 1026 YDAYICYSPKDeeFVIESLARELENGYPSYHLCLHYRDVPqfeaTYAQFPDLVVEATEASRRIIVVLSKNFILTEWSQVE 1105
Cdd:smart00255 2 YDVFISYSGKE--DVRNEFLSHLLEKLRGYGLCVFIDDFE----PGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDE 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2207073696 1106 FRQALQRALRKNPHKLIIVAVGLVARDP-ELKSYFKTGLEITW------KEKRFWERLRYAMPS 1162
Cdd:smart00255 76 LVAALENALEEGGLRVIPIFYEVIPSDVrKQPGKFRKVFKKNYlkwpedEKEQFWKKALYAVPS 139
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
107-508 |
2.87e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 95.00 E-value: 2.87e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 107 NVFEGLRGLKTLKLRSMNNQWGHNKELDLSLGAFNGLRELHTLDLGYNNIRKIPSDLFCALENIISLNLTRNKIKFVDEL 186
Cdd:COG4886 8 LTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 187 GFGHKCGST-LQTIDLSYNDimslpadsEILHLRRLTQLFLQNNKISELPGEvFSDLLSLKVVNLSENAINYLPEGLFQN 265
Cdd:COG4886 88 GLTDLGDLTnLTELDLSGNE--------ELSNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLSNNQLTDLPEPLGNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 266 TrEIREIYLSYNELEIMPKKLFNrLEQLVVLDLSANKLKgdhIEAETFGGLIRLIVLDLSHNAFTGVAQNmFKDLFFLQI 345
Cdd:COG4886 159 T-NLKSLDLSNNQLTDLPEELGN-LTNLKELDLSNNQIT---DLPEPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLET 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 346 LNLSNNSIGFIEDnaFSPLFNLHTLNLAVNKLRTIEDhvfnglfilnklnlnnnilsyvaenaFRNCSDLKELDLSSNKL 425
Cdd:COG4886 233 LDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLPP--------------------------LANLTNLKTLDLSNNQL 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 426 T----KVPEAILQLPFLKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQIGNLTSGMFWGLPSLQVLNLAKNKIQSIET 501
Cdd:COG4886 285 TdlklKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLT 364
|
....*..
gi 2207073696 502 ETFQRNV 508
Cdd:COG4886 365 LLLTLGL 371
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
85-408 |
4.35e-19 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 91.53 E-value: 4.35e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 85 FGKMQGLTEITLSDCKILRLPGNvFEGLRGLKTLKLRsmNNQWghnKELDLSLGafnGLRELHTLDLGYNNIRKIPSDLF 164
Cdd:COG4886 109 LSNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLS--NNQL---TDLPEPLG---NLTNLKSLDLSNNQLTDLPEELG 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 165 cALENIISLNLTRNKIKFV-DELGfghKCgSTLQTIDLSYNDIMSLPAdsEILHLRRLTQLFLQNNKISELPGevFSDLL 243
Cdd:COG4886 180 -NLTNLKELDLSNNQITDLpEPLG---NL-TNLEELDLSGNQLTDLPE--PLANLTNLETLDLSNNQLTDLPE--LGNLT 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 244 SLKVVNLSENAINYLPEGLfqNTREIREIYLSYNELEIMPKKLFNRLEQLVVLDLSANKLKGDHIEAETFGGLIRLIVLD 323
Cdd:COG4886 251 NLEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLL 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 324 LSHNAFTGVAQNMFKDLFFLQILNLSNNSIGFIEDNAFSPLFNLHTLNLAVNKLRTIEDHVFNGLFILNKLNLNNNILSY 403
Cdd:COG4886 329 LLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALL 408
|
....*
gi 2207073696 404 VAENA 408
Cdd:COG4886 409 DAVNT 413
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
128-543 |
2.05e-17 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 88.37 E-value: 2.05e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 128 GHNKELDLSLGAFnGLRELHTLDLGYNNIR-KIPSDLFCALENIISLNLTRNKIKFVDELGFghkcGSTLQTIDLSyNDI 206
Cdd:PLN00113 78 GKNISGKISSAIF-RLPYIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTGSIPRGS----IPNLETLDLS-NNM 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 207 MSLPADSEILHLRRLTQLFLQNNKIS-ELPGEVfSDLLSLKVVNLSENA-INYLPEGLFQnTREIREIYLSYNEL--EIm 282
Cdd:PLN00113 152 LSGEIPNDIGSFSSLKVLDLGGNVLVgKIPNSL-TNLTSLEFLTLASNQlVGQIPRELGQ-MKSLKWIYLGYNNLsgEI- 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 283 PKKLfNRLEQLVVLDLSANKLKG-----------------------DHIEAETFgGLIRLIVLDLSHNAFTGVAQNMFKD 339
Cdd:PLN00113 229 PYEI-GGLTSLNHLDLVYNNLTGpipsslgnlknlqylflyqnklsGPIPPSIF-SLQKLISLDLSDNSLSGEIPELVIQ 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 340 LFFLQILNL-SNNSIGFIEDnAFSPLFNLHTLNLAVNKlrtiedhvFNGLfilnklnlnnnilsyVAENAFRNcSDLKEL 418
Cdd:PLN00113 307 LQNLEILHLfSNNFTGKIPV-ALTSLPRLQVLQLWSNK--------FSGE---------------IPKNLGKH-NNLTVL 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 419 DLSSNKLT-KVPEAILQLPFLKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQI-GNLTSGM----------------- 479
Cdd:PLN00113 362 DLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFsGELPSEFtklplvyfldisnnnlq 441
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696 480 ------FWGLPSLQVLNLAKNKIqSIETETFQRNVQLEAVRLDGNFISD-INGVFVSLTKLLWLNLSENHL 543
Cdd:PLN00113 442 grinsrKWDMPSLQMLSLARNKF-FGGLPDSFGSKRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSENKL 511
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
167-353 |
6.92e-15 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 75.21 E-value: 6.92e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 167 LENIISLNLTRNKIKFVDELgfgHKCGStLQTIDLSYNDIMSLPAdseILHLRRLTQLFLQNNKISELPGevFSDLLSLK 246
Cdd:cd21340 1 LKRITHLYLNDKNITKIDNL---SLCKN-LKVLYLYDNKITKIEN---LEFLTNLTHLYLQNNQIEKIEN--LENLVNLK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 247 VVNLSENAINYLpEGLfQNTREIREIYLSY------NELEIMPKKLFNRLEQLVVLDLSANKLKgdhiEAETFGGLIRLI 320
Cdd:cd21340 72 KLYLGGNRISVV-EGL-ENLTNLEELHIENqrlppgEKLTFDPRSLAALSNSLRVLNISGNNID----SLEPLAPLRNLE 145
|
170 180 190
....*....|....*....|....*....|....*
gi 2207073696 321 VLDLSHNAFTGVAQ--NMFKDLFFLQILNLSNNSI 353
Cdd:cd21340 146 QLDASNNQISDLEEllDLLSSWPSLRELDLTGNPV 180
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
218-442 |
3.71e-14 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 72.90 E-value: 3.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 218 LRRLTQLFLQNNKISELpgEVFSDLLSLKVVNLSENAINYLpEGLFQNTReIREIYLSYNELEIMPKklFNRLEQLVVLD 297
Cdd:cd21340 1 LKRITHLYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKI-ENLEFLTN-LTHLYLQNNQIEKIEN--LENLVNLKKLY 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 298 LSANKLKgdHIEAetFGGLIRLIVLDLSHnaftgvaQNMFKD--LFF-----------LQILNLSNNSIGFIEDnaFSPL 364
Cdd:cd21340 75 LGGNRIS--VVEG--LENLTNLEELHIEN-------QRLPPGekLTFdprslaalsnsLRVLNISGNNIDSLEP--LAPL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 365 FNLHTLNLAVNKLRTIEDhvfnglfilnklnlnnnilsyvAENAFRNCSDLKELDLSSNKLTKVP----EAILQLPFLKS 440
Cdd:cd21340 142 RNLEQLDASNNQISDLEE----------------------LLDLLSSWPSLRELDLTGNPVCKKPkyrdKIILASKSLEV 199
|
..
gi 2207073696 441 LD 442
Cdd:cd21340 200 LD 201
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
97-566 |
7.70e-13 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 73.34 E-value: 7.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 97 SDCKILRLPGNVFEG--------LRGLKTLKLRSmnNQWghNKELDLSLGAfngLRELHTLDLGYNNIR-KIPSDLfCAL 167
Cdd:PLN00113 164 SSLKVLDLGGNVLVGkipnsltnLTSLEFLTLAS--NQL--VGQIPRELGQ---MKSLKWIYLGYNNLSgEIPYEI-GGL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 168 ENIISLNLTRNKIKFVDELGFGHKcgSTLQTIDLsYNDIMSLPADSEILHLRRLTQLFLQNNKIS-ELPgEVFSDLLSLK 246
Cdd:PLN00113 236 TSLNHLDLVYNNLTGPIPSSLGNL--KNLQYLFL-YQNKLSGPIPPSIFSLQKLISLDLSDNSLSgEIP-ELVIQLQNLE 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 247 VVNL-SENAINYLPEGLFQNTReIREIYLSYNEL--EImPKKLFNRlEQLVVLDLSANKLKGDHIEAE-TFGGLIRLIVL 322
Cdd:PLN00113 312 ILHLfSNNFTGKIPVALTSLPR-LQVLQLWSNKFsgEI-PKNLGKH-NNLTVLDLSTNNLTGEIPEGLcSSGNLFKLILF 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 323 D---------------------LSHNAFTGVAQNMFKDLFFLQILNLSNNSI-GFIEDNAFSpLFNLHTLNLAVNKlrti 380
Cdd:PLN00113 389 SnslegeipkslgacrslrrvrLQDNSFSGELPSEFTKLPLVYFLDISNNNLqGRINSRKWD-MPSLQMLSLARNK---- 463
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 381 edhvFNGLFilnklnlnnnilsyvaENAFRNcSDLKELDLSSNKLTK-VPEAILQLPFLKSLDLGENLLTEISNNSFQNL 459
Cdd:PLN00113 464 ----FFGGL----------------PDSFGS-KRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSENKLSGEIPDELSSC 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 460 SQLTGLRLIDNQIGNLTSGMFWGLPSLQVLNLAKNkiqsietetfqrnvqleavRLDGNFISDINGVfvslTKLLWLNLS 539
Cdd:PLN00113 523 KKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQN-------------------QLSGEIPKNLGNV----ESLVQVNIS 579
|
490 500
....*....|....*....|....*..
gi 2207073696 540 ENHLvwfdYAFIPPGLKWLDIHANFIE 566
Cdd:PLN00113 580 HNHL----HGSLPSTGAFLAINASAVA 602
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
194-636 |
6.55e-12 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 70.26 E-value: 6.55e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 194 STLQTIDLSYNDImSLPADSEILHLRRLTQLFLQNNKIS-ELPGEVFSDLLSLKVVNLSENAIN-YLPEGLFQNtreIRE 271
Cdd:PLN00113 69 SRVVSIDLSGKNI-SGKISSAIFRLPYIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTgSIPRGSIPN---LET 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 272 IYLSYNELEIMPKKLFNRLEQLVVLDLSANKLKGdHIEAeTFGGLIRLIVLDLSHNAFTG-----VAQNMFKDLFFLQIL 346
Cdd:PLN00113 145 LDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVG-KIPN-SLTNLTSLEFLTLASNQLVGqipreLGQMKSLKWIYLGYN 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 347 NLS--------------------NNSIGFIEdNAFSPLFNLHTLNLAVNKLR-TIEDHVFNGLFILNKLNLNNNILSYVA 405
Cdd:PLN00113 223 NLSgeipyeiggltslnhldlvyNNLTGPIP-SSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSGEIP 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 406 ENAFRnCSDLKELDLSSNKLT-KVPEAILQLPFLKSLDLGENLLT-EISnnsfQNLSQLTGLRLIDNQIGNLTSGMFWGL 483
Cdd:PLN00113 302 ELVIQ-LQNLEILHLFSNNFTgKIPVALTSLPRLQVLQLWSNKFSgEIP----KNLGKHNNLTVLDLSTNNLTGEIPEGL 376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 484 PS---LQVLNLAKNKIQSIETETFQRNVQLEAVRL-DGNFISDINGVFVSLTKLLWLNLSENHLVWF--DYAFIPPGLKW 557
Cdd:PLN00113 377 CSsgnLFKLILFSNSLEGEIPKSLGACRSLRRVRLqDNSFSGELPSEFTKLPLVYFLDISNNNLQGRinSRKWDMPSLQM 456
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 558 LDIHANfiEVLGNYYKIQNNLNVKTLDASHNRI---VTLNKMSIPNSVELLfINNNFISSIEPDSFLEKNNLTRVDMYAN 634
Cdd:PLN00113 457 LSLARN--KFFGGLPDSFGSKRLENLDLSRNQFsgaVPRKLGSLSELMQLK-LSENKLSGEIPDELSSCKKLVSLDLSHN 533
|
..
gi 2207073696 635 EI 636
Cdd:PLN00113 534 QL 535
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
96-454 |
5.11e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 67.18 E-value: 5.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 96 LSDCKILRLPGNVFEG-----LRGLKTLKLRSM--NNQWGhnkELDLSLGafnGLRELHTLDLGYNNIR-KIPSDLfCAL 167
Cdd:PLN00113 187 LTSLEFLTLASNQLVGqipreLGQMKSLKWIYLgyNNLSG---EIPYEIG---GLTSLNHLDLVYNNLTgPIPSSL-GNL 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 168 ENIISLNLTRNKIKF-VDELGFGHKcgsTLQTIDLSYN----DIMSLPA---DSEILHL----------------RRLTQ 223
Cdd:PLN00113 260 KNLQYLFLYQNKLSGpIPPSIFSLQ---KLISLDLSDNslsgEIPELVIqlqNLEILHLfsnnftgkipvaltslPRLQV 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 224 LFLQNNKISelpGEVFSDL---LSLKVVNLSENAIN-YLPEGLFQNTREIREIYLSyNELEIMPKKLFNRLEQLVVLDLS 299
Cdd:PLN00113 337 LQLWSNKFS---GEIPKNLgkhNNLTVLDLSTNNLTgEIPEGLCSSGNLFKLILFS-NSLEGEIPKSLGACRSLRRVRLQ 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 300 ANKLKGDHieAETFGGLIRLIVLDLSHNAFTGVAQNMFKDLFFLQILNLSNNSI-GFIEDNAFSPlfNLHTLNLAVNKLR 378
Cdd:PLN00113 413 DNSFSGEL--PSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFfGGLPDSFGSK--RLENLDLSRNQFS 488
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696 379 TIEDHVFNGLFILNKLNLNNNILSYVAENAFRNCSDLKELDLSSNKLT-KVPEAILQLPFLKSLDLGENLLT-EISNN 454
Cdd:PLN00113 489 GAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKN 566
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
804-904 |
3.57e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 61.34 E-value: 3.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 804 LYLNSSSVNNIKNetFRSLNDLRILHLDDNKIRYLRGLEFskLSNLKELYLQNNVIEFISNdsFSFLLALEVLRLDGNRL 883
Cdd:cd21340 7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIENLEF--LTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI 80
|
90 100
....*....|....*....|.
gi 2207073696 884 VNygLWHLDNNKKLQTLFVGN 904
Cdd:cd21340 81 SV--VEGLENLTNLEELHIEN 99
|
|
| TIR_2 |
pfam13676 |
TIR domain; This is a family of Toll-like receptors. |
1029-1137 |
4.15e-10 |
|
TIR domain; This is a family of Toll-like receptors.
Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 58.48 E-value: 4.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 1029 YICYSPKDEEFViESLARELE-NGYpsyHLCLHYRDVPqfeaTYAQFPDLVVEATEASRRIIVVLSKNFILTEWSQVEFR 1107
Cdd:pfam13676 2 FISYAGEDRAWA-EWLADALEaAGY---RVWLDRWDIR----PGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWE 73
|
90 100 110
....*....|....*....|....*....|
gi 2207073696 1108 QALQRALRKNphKLIIVAVGLVARDPELKS 1137
Cdd:pfam13676 74 AALADPEGRK--RLIPVRLECDLELPGLAG 101
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
825-883 |
7.15e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 55.99 E-value: 7.15e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696 825 LRILHLDDNKIRYLRGLEFSKLSNLKELYLQNNVIEFISNDSFSFLLALEVLRLDGNRL 883
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
318-654 |
7.59e-10 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 63.71 E-value: 7.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 318 RLIVLDLSHNAFTGVAQNMFKDLFFLQILNLSNNSI-GFIEDNAFSPLFNLHTLNLAVNKlrtiedhvFNGLFILNKLnl 396
Cdd:PLN00113 70 RVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLsGPIPDDIFTTSSSLRYLNLSNNN--------FTGSIPRGSI-- 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 397 nnnilsyvaenafrncSDLKELDLSSNKLT-KVPEAILQLPFLKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQI--- 472
Cdd:PLN00113 140 ----------------PNLETLDLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLvgq 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 473 ------------------GNLTSGM---FWGLPSLQVLNLAKNKIQSIETETFQRNVQLEAVRLDGNFISD-INGVFVSL 530
Cdd:PLN00113 204 iprelgqmkslkwiylgyNNLSGEIpyeIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGpIPPSIFSL 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 531 TKLLWLNLSENHLVwfdyAFIPPglkwLDIHANFIEVLgnyYKIQNNLNVKTLDA--SHNRIVTL----NKMS--IP--- 599
Cdd:PLN00113 284 QKLISLDLSDNSLS----GEIPE----LVIQLQNLEIL---HLFSNNFTGKIPVAltSLPRLQVLqlwsNKFSgeIPknl 352
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2207073696 600 ---NSVELLFINNNFISSIEPDSFLEKNNLTRVDMYANEIE-----SL-DINSLRISRVDEQAL 654
Cdd:PLN00113 353 gkhNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEgeipkSLgACRSLRRVRLQDNSF 416
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
219-279 |
2.73e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 54.45 E-value: 2.73e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696 219 RRLTQLFLQNNKISELPGEVFSDLLSLKVVNLSENAINYLPEGLFQNTREIREIYLSYNEL 279
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
146-353 |
2.75e-09 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 61.64 E-value: 2.75e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 146 LHTLDLGYNNIRKIPSDLfcaLENIISLNLTRNKIKFVDElgfghKCGSTLQTIDLSYNDIMSLPaDSEILHLRRLTqlf 225
Cdd:PRK15370 222 IKTLYANSNQLTSIPATL---PDTIQEMELSINRITELPE-----RLPSALQSLDLFHNKISCLP-ENLPEELRYLS--- 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 226 LQNNKISELPGEVFSDLLSLKVVNlseNAINYLPEGLFQNtreIREIYLSYNELEIMPKKLFNRLEqlvVLDLSANKLKg 305
Cdd:PRK15370 290 VYDNSIRTLPAHLPSGITHLNVQS---NSLTALPETLPPG---LKTLEAGENALTSLPASLPPELQ---VLDVSKNQIT- 359
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2207073696 306 dhIEAETFGGLIRliVLDLSHNAFTGVAQNMFKDlffLQILNLSNNSI 353
Cdd:PRK15370 360 --VLPETLPPTIT--TLDVSRNALTNLPENLPAA---LQIMQASRNNL 400
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
222-462 |
5.81e-09 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 60.48 E-value: 5.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 222 TQLFLQNNKISELPGEVFSDLLSLKvvnLSENAINYLPEGLFQNtreIREIYLSYNELEIMPKKLFNRLEqlvVLDLSAN 301
Cdd:PRK15370 181 TELRLKILGLTTIPACIPEQITTLI---LDNNELKSLPENLQGN---IKTLYANSNQLTSIPATLPDTIQ---EMELSIN 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 302 KLKG--DHIEAEtfgglirLIVLDLSHNAFTGVAQNMFKDlffLQILNLSNNSIGFIEDNAFSPLFNLHTLNlavNKLRT 379
Cdd:PRK15370 252 RITElpERLPSA-------LQSLDLFHNKISCLPENLPEE---LRYLSVYDNSIRTLPAHLPSGITHLNVQS---NSLTA 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 380 IEDHVFNGLFILNklnlnnnilsyVAENAFRNC-----SDLKELDLSSNKLTKVPEAIlqLPFLKSLDLGENLLTEISNN 454
Cdd:PRK15370 319 LPETLPPGLKTLE-----------AGENALTSLpaslpPELQVLDVSKNQITVLPETL--PPTITTLDVSRNALTNLPEN 385
|
250
....*....|....*...
gi 2207073696 455 ----------SFQNLSQL 462
Cdd:PRK15370 386 lpaalqimqaSRNNLVRL 403
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
438-496 |
1.21e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 52.53 E-value: 1.21e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696 438 LKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQIGNLTSGMFWGLPSLQVLNLAKNKI 496
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
415-472 |
2.11e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.76 E-value: 2.11e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696 415 LKELDLSSNKLTKV-PEAILQLPFLKSLDLGENLLTEISNNSFQNLSQLTGLRLIDNQI 472
Cdd:pfam13855 3 LRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
292-353 |
2.13e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.76 E-value: 2.13e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2207073696 292 QLVVLDLSANKLKgdHIEAETFGGLIRLIVLDLSHNAFTGVAQNMFKDLFFLQILNLSNNSI 353
Cdd:pfam13855 2 NLRSLDLSNNRLT--SLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
778-905 |
2.53e-08 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 57.64 E-value: 2.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 778 THIYLDGNNYNVLNESVFNsMHKAMVLYLNSSSVNNIkNETFRSLNDLRILHLDDNKIRYLrGLEFSKLSNLKELYLQNN 857
Cdd:COG4886 116 ESLDLSGNQLTDLPEELAN-LTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNN 192
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2207073696 858 VIEFISnDSFSFLLALEVLRLDGNRLVNYGLWhLDNNKKLQTLFVGNN 905
Cdd:COG4886 193 QITDLP-EPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNN 238
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
1026-1160 |
3.31e-08 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 54.29 E-value: 3.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 1026 YDAYICYSPKDEE--FVIESLARELENGYpsyHLCLHYRDVPQFEAtYAqfpDLVVEATEASRRIIVVLSKNFILTEWSQ 1103
Cdd:pfam01582 1 YDVFLSFRGSDTRewFVSHLLKELKQKGI---KLFIDDRDLEPGEA-IA---PELLSAIEKSRRSVVVLSPNYASSGWCL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 1104 VEFRQALQRALRKNpHKLIIVAVGLVARD--------PELKSYFKTGLE----ITWK-----------------EKRFWE 1154
Cdd:pfam01582 74 DELVKILECALDLG-QKVIPIFYEVDPSDvrkqtgsfGKAFKKHKKVLTeekvLKWRgalnevaniwhsksvsdESKFWK 152
|
....*.
gi 2207073696 1155 RLRYAM 1160
Cdd:pfam01582 153 KIAYDI 158
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
318-377 |
1.99e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 49.06 E-value: 1.99e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 318 RLIVLDLSHNAFTGVAQNMFKDLFFLQILNLSNNSIGFIEDNAFSPLFNLHTLNLAVNKL 377
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
802-859 |
2.86e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 2.86e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696 802 MVLYLNSSSVNNIKNETFRSLNDLRILHLDDNKIRYLRGLEFSKLSNLKELYLQNNVI 859
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
484-543 |
5.20e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.90 E-value: 5.20e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696 484 PSLQVLNLAKNKIQSIETETFQRNVQLEAVRLDGNFISDIN-GVFVSLTKLLWLNLSENHL 543
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSpGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
291-496 |
1.08e-06 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 51.97 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 291 EQLVVLDLSANKLKGD----HIEAETFGGLIRLIVLDLSHNAFTGVAQNMFKDL---FFLQILNLSNNSIG-----FIED 358
Cdd:cd00116 51 PSLKELCLSLNETGRIprglQSLLQGLTKGCGLQELDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLGdrglrLLAK 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 359 ----------------------------NAFSPLFNLHTLNLAVNKLRtiedhvfnglfilnklnlnNNILSYVAEnAFR 410
Cdd:cd00116 131 glkdlppaleklvlgrnrlegascealaKALRANRDLKELNLANNGIG-------------------DAGIRALAE-GLK 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 411 NCSDLKELDLSSNKLT-----KVPEAILQLPFLKSLDLGENLLT-----EISNNSFQNLSQLTGLRLIDNQIGNLTSGMF 480
Cdd:cd00116 191 ANCNLEVLDLNNNGLTdegasALAETLASLKSLEVLNLGDNNLTdagaaALASALLSPNISLLTLSLSCNDITDDGAKDL 270
|
250 260
....*....|....*....|
gi 2207073696 481 WGL----PSLQVLNLAKNKI 496
Cdd:cd00116 271 AEVlaekESLLELDLRGNKF 290
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
460-518 |
1.27e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 46.75 E-value: 1.27e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696 460 SQLTGLRLIDNQIGNLTSGMFWGLPSLQVLNLAKNKIQSIETETFQRNVQLEAVRLDGN 518
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
83-329 |
1.40e-06 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 51.59 E-value: 1.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 83 HYFGKMQGLTEITLSDCKILRLPGNVFEGLRGLKTLKLRSMNNqwghnkeldlslgafNGLRELHTLDLGynnirKIPSD 162
Cdd:cd00116 75 QGLTKGCGLQELDLSDNALGPDGCGVLESLLRSSSLQELKLNN---------------NGLGDRGLRLLA-----KGLKD 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 163 LFCALEniiSLNLTRNKIKF--VDELGFGHKCGSTLQTIDLSYNDIMS--LPADSEIL-HLRRLTQLFLQNNKISELPG- 236
Cdd:cd00116 135 LPPALE---KLVLGRNRLEGasCEALAKALRANRDLKELNLANNGIGDagIRALAEGLkANCNLEVLDLNNNGLTDEGAs 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 237 ---EVFSDLLSLKVVNLSENAIN-----YLPEGLFQNTREIREIYLSYNELEIMPKKLFNRL----EQLVVLDLSANKLK 304
Cdd:cd00116 212 alaETLASLKSLEVLNLGDNNLTdagaaALASALLSPNISLLTLSLSCNDITDDGAKDLAEVlaekESLLELDLRGNKFG 291
|
250 260
....*....|....*....|....*...
gi 2207073696 305 --GDHIEAETFGGLI-RLIVLDLSHNAF 329
Cdd:cd00116 292 eeGAQLLAESLLEPGnELESLWVKDDSF 319
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
267-327 |
3.10e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.59 E-value: 3.10e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696 267 REIREIYLSYNELEIMPKKLFNRLEQLVVLDLSANKLKgdHIEAETFGGLIRLIVLDLSHN 327
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT--TLSPGAFSGLPSLRYLDLSGN 59
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
144-206 |
4.77e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.21 E-value: 4.77e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2207073696 144 RELHTLDLGYNNIRKIPSDLFCALENIISLNLTRNKIKFVDELGFGHkCGStLQTIDLSYNDI 206
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSG-LPS-LRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
220-427 |
8.16e-06 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 49.28 E-value: 8.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 220 RLTQLFLQNNKISELPGEVFSDLL---SLKVVNLSENAIN-----YLPEGLFQNTREIREIYLSYNELEIMP----KKLF 287
Cdd:cd00116 82 GLQELDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGdrglrLLAKGLKDLPPALEKLVLGRNRLEGAScealAKAL 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 288 NRLEQLVVLDLSANKLKGDHIE--AETFGGLIRLIVLDLSHNAFT--GVAQ--NMFKDLFFLQILNLSNNSIGF-----I 356
Cdd:cd00116 162 RANRDLKELNLANNGIGDAGIRalAEGLKANCNLEVLDLNNNGLTdeGASAlaETLASLKSLEVLNLGDNNLTDagaaaL 241
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2207073696 357 EDNAFSPLFNLHTLNLAVNKlrtIEDHVFnglfilnklnlnNNILSYVAENafrncSDLKELDLSSNKLTK 427
Cdd:cd00116 242 ASALLSPNISLLTLSLSCND---ITDDGA------------KDLAEVLAEK-----ESLLELDLRGNKFGE 292
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
131-286 |
2.16e-05 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 48.92 E-value: 2.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 131 KELDLSLGAFNGL-----RELHTLDLGYNNIRKIPSDLfcaLENIISLNLTRNKIKFVDE-LGFGhkcgstLQTIDLSYN 204
Cdd:PRK15370 265 QSLDLFHNKISCLpenlpEELRYLSVYDNSIRTLPAHL---PSGITHLNVQSNSLTALPEtLPPG------LKTLEAGEN 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 205 DIMSLPADSEilhlRRLTQLFLQNNKISELPGEVFSDLLSLKVvnlSENAINYLPEGLfqnTREIREIYLSYNELEIMPK 284
Cdd:PRK15370 336 ALTSLPASLP----PELQVLDVSKNQITVLPETLPPTITTLDV---SRNALTNLPENL---PAALQIMQASRNNLVRLPE 405
|
..
gi 2207073696 285 KL 286
Cdd:PRK15370 406 SL 407
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
418-636 |
2.85e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 46.70 E-value: 2.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 418 LDLSSNKLTKVpEAILQLPFLKSLDLGENLLTEISNnsFQNLSQLTGLRLIDNQI---GNLTSgmfwgLPSLQVLNLAKN 494
Cdd:cd21340 7 LYLNDKNITKI-DNLSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIekiENLEN-----LVNLKKLYLGGN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 495 KIQSIEtetfqrnvQLEavrldgnfisdingvfvSLTKLLWLNLSENHLvwfdyafiPPGLKwLDIHANFIEVLGNyyki 574
Cdd:cd21340 79 RISVVE--------GLE-----------------NLTNLEELHIENQRL--------PPGEK-LTFDPRSLAALSN---- 120
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2207073696 575 qnnlNVKTLDASHNRIVTLNKMSIPNSVELLFINNNFISSIEPDSFLEKN--NLTRVDMYANEI 636
Cdd:cd21340 121 ----SLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEELLDLLSSwpSLRELDLTGNPV 180
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
140-255 |
3.10e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 46.70 E-value: 3.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 140 FNGLRELHTLDLGYNNIRKIpSDLFCaLENIISLNLTRNKIKFVDELGFGHKC----GSTLQTIDLSYNDIMSLpadSEI 215
Cdd:cd21340 64 LENLVNLKKLYLGGNRISVV-EGLEN-LTNLEELHIENQRLPPGEKLTFDPRSlaalSNSLRVLNISGNNIDSL---EPL 138
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2207073696 216 LHLRRLTQLFLQNNKISELP--GEVFSDLLSLKVVNLSENAI 255
Cdd:cd21340 139 APLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
113-180 |
3.79e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.51 E-value: 3.79e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696 113 RGLKTLKLRsmnnqwgHNKELDLSLGAFNGLRELHTLDLGYNNIRKIPSDLFCALENIISLNLTRNKI 180
Cdd:pfam13855 1 PNLRSLDLS-------NNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
89-156 |
3.90e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.51 E-value: 3.90e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696 89 QGLTEITLSDCKILRLPGNVFEGLRGLKTLKLrsmnnqwGHNKELDLSLGAFNGLRELHTLDLGYNNI 156
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDL-------SNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
289-353 |
4.13e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 47.89 E-value: 4.13e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2207073696 289 RLEQLVVLDLSANKLKGDhIEAeTFGGLIRLIVLDLSHNAFTGVAQNMFKDLFFLQILNLSNNSI 353
Cdd:PLN03150 440 KLRHLQSINLSGNSIRGN-IPP-SLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
125-378 |
4.63e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.48 E-value: 4.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 125 NQWGHNKELDLSLGAFNGLRELHTLDLGYNNIrkipsdlfcALENIISL--NLTRNKikfvdelgfghkcgsTLQTIDLS 202
Cdd:COG5238 161 LAARLGLLAAISMAKALQNNSVETVYLGCNQI---------GDEGIEELaeALTQNT---------------TVTTLWLK 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 203 YNDIMSLPADSEILHLR---RLTQLFLQNNKISELPGEVFSDLL----SLKVVNLSENAIN-----YLPEGLFQNTrEIR 270
Cdd:COG5238 217 RNPIGDEGAEILAEALKgnkSLTTLDLSNNQIGDEGVIALAEALknntTVETLYLSGNQIGaegaiALAKALQGNT-TLT 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 271 EIYLSYNEL-EIMPKKLFNRLEQ---LVVLDLSANKLKGDHIE--AETFGGLIRLIVLDLSHNAFT-----GVAQNMfKD 339
Cdd:COG5238 296 SLDLSVNRIgDEGAIALAEGLQGnktLHTLNLAYNGIGAQGAIalAKALQENTTLHSLDLSDNQIGdegaiALAKYL-EG 374
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2207073696 340 LFFLQILNLSNNSI---GFIEDNAFSPLFNLHTLNLAVNKLR 378
Cdd:COG5238 375 NTTLRELNLGKNNIgkqGAEALIDALQTNRLHTLILDGNLIG 416
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
343-425 |
4.79e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.13 E-value: 4.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 343 LQILNLSNNSIGFIEDNAFSPLFNLHTLNLAVNKLRTIEDHvfnglfilnklnlnnnilsyvaenAFRNCSDLKELDLSS 422
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPG------------------------AFSGLPSLRYLDLSG 58
|
...
gi 2207073696 423 NKL 425
Cdd:pfam13855 59 NRL 61
|
|
| LRR_5 |
pfam13306 |
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ... |
351-463 |
6.74e-05 |
|
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.
Pssm-ID: 463839 [Multi-domain] Cd Length: 127 Bit Score: 43.69 E-value: 6.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 351 NSIGFIEDNAFSPLFNLHTLNLAvNKLRTIEDHVFNGLFILNKLNLNNNilSYVAENAFRNCSDLKELDLSSNkLTKVPE 430
Cdd:pfam13306 20 SSLTSIGEYAFSNCTSLKSITLP-SSLTSIGSYAFYNCSLTSITIPSSL--TSIGEYAFSNCSNLKSITLPSN-LTSIGS 95
|
90 100 110
....*....|....*....|....*....|...
gi 2207073696 431 AILQLPFLKSLDLGENlLTEISNNSFQNLSQLT 463
Cdd:pfam13306 96 YAFSNCSLKSITIPSS-VTTIGSYAFSNCSNLK 127
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
778-904 |
7.16e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 45.55 E-value: 7.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 778 THIYLDGNNYNVLNEsvFNSMHKAMVLYLNSSSVNNIKN--------------------ETFRSLNDLRILHLDDNKIRY 837
Cdd:cd21340 5 THLYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIENlefltnlthlylqnnqiekiENLENLVNLKKLYLGGNRISV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 838 LRGLEfsKLSNLKELYLQN------NVIEF----------------ISN------DSFSFLLALEVLRLDGNRLVNYG-- 887
Cdd:cd21340 83 VEGLE--NLTNLEELHIENqrlppgEKLTFdprslaalsnslrvlnISGnnidslEPLAPLRNLEQLDASNNQISDLEel 160
|
170
....*....|....*...
gi 2207073696 888 LWHLDNNKKLQTL-FVGN 904
Cdd:cd21340 161 LDLLSSWPSLRELdLTGN 178
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
778-835 |
8.15e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.74 E-value: 8.15e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696 778 THIYLDGNNYNVLNESVFNSMHKAMVLYLNSSSVNNIKNETFRSLNDLRILHLDDNKI 835
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
194-255 |
1.29e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 40.97 E-value: 1.29e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2207073696 194 STLQTIDLSYNDIMSLPADSeILHLRRLTQLFLQNNKISELPGEVFSDLLSLKVVNLSENAI 255
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGA-FKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
742-779 |
2.02e-04 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 39.61 E-value: 2.02e-04
10 20 30
....*....|....*....|....*....|....*...
gi 2207073696 742 CPNNCSCyHDStkttnVVDCSVKQLDAVPRDFPNGATH 779
Cdd:smart00013 2 CPAPCNC-SGT-----AVDCSGRGLTEVPLDLPPDTTL 33
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
244-522 |
2.25e-04 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 45.17 E-value: 2.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 244 SLKVVNLSENAIN-----YLPEGLFQNTrEIREIYLSYNE-----LEIMPKKLfNRLEQLVVLDLSANKLK--GDHIEAE 311
Cdd:COG5238 181 SVETVYLGCNQIGdegieELAEALTQNT-TVTTLWLKRNPigdegAEILAEAL-KGNKSLTTLDLSNNQIGdeGVIALAE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 312 TFGGLIRLIVLDLSHNAFT-----GVAQNmfkdlfflqilnLSNNSigfiednafsplfNLHTLNLAVNKLRtiedhvfn 386
Cdd:COG5238 259 ALKNNTTVETLYLSGNQIGaegaiALAKA------------LQGNT-------------TLTSLDLSVNRIG-------- 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 387 glfilnklnlnnnILSYVA-ENAFRNCSDLKELDLSSNKLTKVpEAILqlpflksldLGENLlteisnnsfQNLSQLTGL 465
Cdd:COG5238 306 -------------DEGAIAlAEGLQGNKTLHTLNLAYNGIGAQ-GAIA---------LAKAL---------QENTTLHSL 353
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2207073696 466 RLIDNQIGNltSGM------FWGLPSLQVLNLAKNKIQSIETETF----QRNvQLEAVRLDGNFISD 522
Cdd:COG5238 354 DLSDNQIGD--EGAialakyLEGNTTLRELNLGKNNIGKQGAEALidalQTN-RLHTLILDGNLIGA 417
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
408-543 |
4.01e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 43.88 E-value: 4.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 408 AFRNCSDLKELDLSSNKLTK----VPEAILQLPFLKSLDLGENLL----TEISNNSFQNLS-QLTGLRLIDNQIGNL--- 475
Cdd:cd00116 76 GLTKGCGLQELDLSDNALGPdgcgVLESLLRSSSLQELKLNNNGLgdrgLRLLAKGLKDLPpALEKLVLGRNRLEGAsce 155
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696 476 -TSGMFWGLPSLQVLNLAKNKI--QSIET--ETFQRNVQLEAVRLDGNFISDIN-----GVFVSLTKLLWLNLSENHL 543
Cdd:cd00116 156 aLAKALRANRDLKELNLANNGIgdAGIRAlaEGLKANCNLEVLDLNNNGLTDEGasalaETLASLKSLEVLNLGDNNL 233
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
817-905 |
4.08e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 43.88 E-value: 4.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 817 ETFRSLNDLRILHLDDNK-----IRYLrGLEFSKLSNLKELYLQNNVIE-----FISnDSFSFLLALEVLRLDGNRLVNY 886
Cdd:cd00116 159 KALRANRDLKELNLANNGigdagIRAL-AEGLKANCNLEVLDLNNNGLTdegasALA-ETLASLKSLEVLNLGDNNLTDA 236
|
90 100
....*....|....*....|....
gi 2207073696 887 GLWHLDN-----NKKLQTLFVGNN 905
Cdd:cd00116 237 GAAALASallspNISLLTLSLSCN 260
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
366-448 |
6.05e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.04 E-value: 6.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 366 NLHTLNLAVNKLRTIEDHvfnglfilnklnlnnnilsyvaenAFRNCSDLKELDLSSNKLTKV-PEAILQLPFLKSLDLG 444
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDG------------------------AFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLS 57
|
....
gi 2207073696 445 ENLL 448
Cdd:pfam13855 58 GNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
847-905 |
7.30e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.04 E-value: 7.30e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2207073696 847 SNLKELYLQNNVIEFISNDSFSFLLALEVLRLDGNRLVNYGLWHLDNNKKLQTLFVGNN 905
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| LRRNT |
pfam01462 |
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ... |
742-774 |
8.27e-04 |
|
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.
Pssm-ID: 396168 [Multi-domain] Cd Length: 28 Bit Score: 37.99 E-value: 8.27e-04
10 20 30
....*....|....*....|....*....|...
gi 2207073696 742 CPNNCSCyHDStkttnVVDCSVKQLDAVPRDFP 774
Cdd:pfam01462 2 CPVPCHC-SAT-----VVNCSDRGLTAVPRDLP 28
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
732-905 |
1.65e-03 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 42.23 E-value: 1.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 732 DFSFCNCKTVCPNNCSCYHDSTKTTNVVDCSVKQLDAVPRDFPNGATHIYLDGNNYNVLNESVFNSMHKAMVLYLNSSSV 811
Cdd:COG4886 5 LLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 812 NNIKNETFRSLNDLRILHLDDNKirylrglEFSKLSNLKELYLQNNVIEFISnDSFSFLLALEVLRLDGNRLVNYGLWhL 891
Cdd:COG4886 85 LLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLP-EELANLTNLKELDLSNNQLTDLPEP-L 155
|
170
....*....|....
gi 2207073696 892 DNNKKLQTLFVGNN 905
Cdd:COG4886 156 GNLTNLKSLDLSNN 169
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
159-254 |
1.90e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 42.50 E-value: 1.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 159 IPSDLfCALENIISLNLTRNKIKFVDELGFGHKcgSTLQTIDLSYNDIMSLPADS--EILHLRRLTqlfLQNNKIS-ELP 235
Cdd:PLN03150 434 IPNDI-SKLRHLQSINLSGNSIRGNIPPSLGSI--TSLEVLDLSYNSFNGSIPESlgQLTSLRILN---LNGNSLSgRVP 507
|
90
....*....|....*....
gi 2207073696 236 GEVFSDLLSLKVVNLSENA 254
Cdd:PLN03150 508 AALGGRLLHRASFNFTDNA 526
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
415-543 |
2.34e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 42.08 E-value: 2.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 415 LKELDLSSNKLTKvPEAILQLPFLK------SLDLGENLLTEIS----NNSFQNLSQLTGLRLIDNQIGN-----LTSGM 479
Cdd:COG5238 238 LTTLDLSNNQIGD-EGVIALAEALKnnttveTLYLSGNQIGAEGaialAKALQGNTTLTSLDLSVNRIGDegaiaLAEGL 316
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2207073696 480 fWGLPSLQVLNLAKNKIQSIET----ETFQRNVQLEAVRLDGNFISDINGV-----FVSLTKLLWLNLSENHL 543
Cdd:COG5238 317 -QGNKTLHTLNLAYNGIGAQGAialaKALQENTTLHSLDLSDNQIGDEGAIalakyLEGNTTLRELNLGKNNI 388
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
662-719 |
5.01e-03 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 36.25 E-value: 5.01e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2207073696 662 NPFRCDCTMKWLLLINsittREYPRVMDLENVICKESyvrGVKYLPVSSLHTKDFLCK 719
Cdd:smart00082 1 NPFICDCELRWLLRWL----QANEHLQDPVDLRCASP---SSLRGPLLELLHSEFKCP 51
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
45-243 |
6.40e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 40.54 E-value: 6.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 45 NVRTLSSDRDVIGSmhsDGAERLAircgSHLLESTlkdhyfgkmqGLTEITLSDCKI----LRLPGNVFEGLRGLKTLKL 120
Cdd:COG5238 209 TVTTLWLKRNPIGD---EGAEILA----EALKGNK----------SLTTLDLSNNQIgdegVIALAEALKNNTTVETLYL 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 121 RSmnNQWGHN---------------KELDLSL------GAF---NGLRE---LHTLDLGYNNIRK---IPsdLFCALE-- 168
Cdd:COG5238 272 SG--NQIGAEgaialakalqgnttlTSLDLSVnrigdeGAIalaEGLQGnktLHTLNLAYNGIGAqgaIA--LAKALQen 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 169 -NIISLNLTRNKI--KFVDELGFGHKCGSTLQTIDLSYNDIMSLPADSEILHLR--RLTQLFLQNNKISELPGEVFSDLL 243
Cdd:COG5238 348 tTLHSLDLSDNQIgdEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQtnRLHTLILDGNLIGAEAQQRLEQLL 427
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
778-905 |
7.38e-03 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 40.30 E-value: 7.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207073696 778 THIYLDGNNYNVLNESVFNsMHKAMVLYLNSSSVNNIKNetFRSLNDLRILHLDDNKIRYLRglEFSKLSNLKELYLQNN 857
Cdd:COG4886 208 EELDLSGNQLTDLPEPLAN-LTNLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLP--PLANLTNLKTLDLSNN 282
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2207073696 858 VIEFISNDSFSFLLALEVLRLDGNRLVNYGLWHLDNNKKLQTLFVGNN 905
Cdd:COG4886 283 QLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLL 330
|
|
| |
