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Conserved domains on  [gi|2194090446|ref|XP_046557394|]
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arsenite methyltransferase-like isoform X1 [Haliotis rubra]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 1000582)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor; similar to Homo sapiens arsenite methyltransferase

CATH:  3.40.50.150
EC:  2.1.1.-
Gene Ontology:  GO:1904047|GO:0008168|GO:0032259|GO:0008757
PubMed:  12826405|12504684
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
arsM super family cl30592
arsenite methyltransferase;
88-292 5.63e-47

arsenite methyltransferase;


The actual alignment was detected with superfamily member PRK11873:

Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 161.27  E-value: 5.63e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  88 GCG--MVIPEKLEGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKhvgySTERFGYSkpNLEFFVGYIE 165
Cdd:PRK11873   65 GCGnpTALAELKPGETVLDLGSGGGFDCFLAARRVGPTGKVIGVDMTPEMLAKARA----NARKAGYT--NVEFRLGEIE 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 166 KLAekgIGDNSFNILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSDVYCSKELPEEVRKNEYLWSMCIAGSLYWKRLH 245
Cdd:PRK11873  139 ALP---VADNSVDVIISNCVINLSPDKERVFKEAFRVLKPGGRFAISDVVLRGELPEEIRNDAELYAGCVAGALQEEEYL 215

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2194090446 246 DIAKEVGFCV----PRVVEITTVAINNEEYKTLV----GDARFVSITYRMFKLPA 292
Cdd:PRK11873  216 AMLAEAGFVDitiqPKREYRIPDAREFLEDWGIApgrqLDGYIVSATVEATKPAA 270
 
Name Accession Description Interval E-value
arsM PRK11873
arsenite methyltransferase;
88-292 5.63e-47

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 161.27  E-value: 5.63e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  88 GCG--MVIPEKLEGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKhvgySTERFGYSkpNLEFFVGYIE 165
Cdd:PRK11873   65 GCGnpTALAELKPGETVLDLGSGGGFDCFLAARRVGPTGKVIGVDMTPEMLAKARA----NARKAGYT--NVEFRLGEIE 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 166 KLAekgIGDNSFNILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSDVYCSKELPEEVRKNEYLWSMCIAGSLYWKRLH 245
Cdd:PRK11873  139 ALP---VADNSVDVIISNCVINLSPDKERVFKEAFRVLKPGGRFAISDVVLRGELPEEIRNDAELYAGCVAGALQEEEYL 215

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2194090446 246 DIAKEVGFCV----PRVVEITTVAINNEEYKTLV----GDARFVSITYRMFKLPA 292
Cdd:PRK11873  216 AMLAEAGFVDitiqPKREYRIPDAREFLEDWGIApgrqLDGYIVSATVEATKPAA 270
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 98-252 1.97e-35

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 126.76  E-value: 1.97e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  98 EGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKHvgysTERFGYSkpNLEFFVGYIEKLaEKGIGDNSF 177
Cdd:pfam13847   3 KGMRVLDLGCGTGHLSFELAEELGPNAEVVGIDISEEAIEKAREN----AQKLGFD--NVEFEQGDIEEL-PELLEDDKF 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2194090446 178 NILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSDVYCSKELPEEVRKNEYLWSMCIAGSLYWKRLHDIAKEVG 252
Cdd:pfam13847  76 DVVISNCVLNHIPDPDKVLQEILRVLKPGGRLIISDPDSLAELPAHVKEDSTYYAGCVGGAILKKKLYELLEEAG 150
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 98-213 1.38e-23

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 95.06  E-value: 1.38e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  98 EGQKVLDLGCGAGRDTYIVSKLvgpEGSIVGVDMTDALIEVANkhvgystERFGYSKPNLEFFVGYIEKLAekgIGDNSF 177
Cdd:COG2226    22 PGARVLDLGCGTGRLALALAER---GARVTGVDISPEMLELAR-------ERAAEAGLNVEFVVGDAEDLP---FPDGSF 88

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2194090446 178 NILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSD 213
Cdd:COG2226    89 DLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVD 124
MenG_MenH_UbiE TIGR01934
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ...
 80-253 2.52e-15

ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273884 [Multi-domain]  Cd Length: 223  Bit Score: 74.22  E-value: 2.52e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  80 QDVLDRYYGCGMVIPEKleGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKhvgysteRFGySKPNLEF 159
Cdd:TIGR01934  23 LHRLWRRRAVKLIGVFK--GQKVLDVACGTGDLAIELAKSAPDRGKVTGVDFSSEMLEVAKK-------KSE-LPLNIEF 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 160 FVGYIEKLAEKgigDNSFNIL-VSNGVINLTsDKKAVLQEAYRVLKEGGELY--------------FSDVYCSKELP--- 221
Cdd:TIGR01934  93 IQADAEALPFE---DNSFDAVtIAFGLRNVT-DIQKALREMYRVLKPGGRLVilefskpanallkkFYKFYLKNVLPsig 168

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2194090446 222 EEVRKN----EYLwSMCIAGSLYWKRLHDIAKEVGF 253
Cdd:TIGR01934 169 GLISKNaeayTYL-PESIRAFPSQEELAAMLKEAGF 203
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 101-216 8.77e-14

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 67.07  E-value: 8.77e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 101 KVLDLGCGAGRDTYIVSKlvGPEGSIVGVDMTDALIEVANKhvgystERFGYSKPNLEFFVGYIEKLAEKGigDNSFNIL 180
Cdd:cd02440     1 RVLDLGCGTGALALALAS--GPGARVTGVDISPVALELARK------AAAALLADNVEVLKGDAEELPPEA--DESFDVI 70

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2194090446 181 VSNGVIN-LTSDKKAVLQEAYRVLKEGGELYFSDVYC 216
Cdd:cd02440    71 ISDPPLHhLVEDLARFLEEARRLLKPGGVLVLTLVLA 107
 
Name Accession Description Interval E-value
arsM PRK11873
arsenite methyltransferase;
88-292 5.63e-47

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 161.27  E-value: 5.63e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  88 GCG--MVIPEKLEGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKhvgySTERFGYSkpNLEFFVGYIE 165
Cdd:PRK11873   65 GCGnpTALAELKPGETVLDLGSGGGFDCFLAARRVGPTGKVIGVDMTPEMLAKARA----NARKAGYT--NVEFRLGEIE 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 166 KLAekgIGDNSFNILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSDVYCSKELPEEVRKNEYLWSMCIAGSLYWKRLH 245
Cdd:PRK11873  139 ALP---VADNSVDVIISNCVINLSPDKERVFKEAFRVLKPGGRFAISDVVLRGELPEEIRNDAELYAGCVAGALQEEEYL 215

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2194090446 246 DIAKEVGFCV----PRVVEITTVAINNEEYKTLV----GDARFVSITYRMFKLPA 292
Cdd:PRK11873  216 AMLAEAGFVDitiqPKREYRIPDAREFLEDWGIApgrqLDGYIVSATVEATKPAA 270
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 98-252 1.97e-35

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 126.76  E-value: 1.97e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  98 EGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKHvgysTERFGYSkpNLEFFVGYIEKLaEKGIGDNSF 177
Cdd:pfam13847   3 KGMRVLDLGCGTGHLSFELAEELGPNAEVVGIDISEEAIEKAREN----AQKLGFD--NVEFEQGDIEEL-PELLEDDKF 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2194090446 178 NILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSDVYCSKELPEEVRKNEYLWSMCIAGSLYWKRLHDIAKEVG 252
Cdd:pfam13847  76 DVVISNCVLNHIPDPDKVLQEILRVLKPGGRLIISDPDSLAELPAHVKEDSTYYAGCVGGAILKKKLYELLEEAG 150
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 98-213 1.38e-23

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 95.06  E-value: 1.38e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  98 EGQKVLDLGCGAGRDTYIVSKLvgpEGSIVGVDMTDALIEVANkhvgystERFGYSKPNLEFFVGYIEKLAekgIGDNSF 177
Cdd:COG2226    22 PGARVLDLGCGTGRLALALAER---GARVTGVDISPEMLELAR-------ERAAEAGLNVEFVVGDAEDLP---FPDGSF 88

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2194090446 178 NILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSD 213
Cdd:COG2226    89 DLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVD 124
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 102-207 8.64e-22

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 88.77  E-value: 8.64e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 102 VLDLGCGAGRDTYIVSKLVGpeGSIVGVDMTDALIEVANkhvgystERFGYSKPNLEFFVGYIEKLAEKgigDNSFNILV 181
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGG--ARVTGVDLSPEMLERAR-------ERAAEAGLNVEFVQGDAEDLPFP---DGSFDLVV 68

                          90       100
                  ....*....|....*....|....*...
gi 2194090446 182 SNGVINLTS--DKKAVLQEAYRVLKEGG 207
Cdd:pfam13649  69 SSGVLHHLPdpDLEAALREIARVLKPGG 96
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 97-213 5.25e-18

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 79.29  E-value: 5.25e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  97 LEGQKVLDLGCGAGRDTYIVSKLvgpeG-SIVGVDMTDALIEVANKHvgysterfgYSKPNLEFFVGYIEKLAekgIGDN 175
Cdd:COG2227    23 PAGGRVLDVGCGTGRLALALARR----GaDVTGVDISPEALEIARER---------AAELNVDFVQGDLEDLP---LEDG 86

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2194090446 176 SFNILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSD 213
Cdd:COG2227    87 SFDLVICSEVLEHLPDPAALLRELARLLKPGGLLLLST 124
PRK08317 PRK08317
hypothetical protein; Provisional
 98-207 1.70e-17

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 80.75  E-value: 1.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  98 EGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVAnkhvgysTERFGYSKPNLEFFVGYIEKLaekGIGDNSF 177
Cdd:PRK08317   19 PGDRVLDVGCGPGNDARELARRVGPEGRVVGIDRSEAMLALA-------KERAAGLGPNVEFVRGDADGL---PFPDGSF 88

                          90       100       110
                  ....*....|....*....|....*....|
gi 2194090446 178 NILVSNGVINLTSDKKAVLQEAYRVLKEGG 207
Cdd:PRK08317   89 DAVRSDRVLQHLEDPARALAEIARVLRPGG 118
Ubie_methyltran pfam01209
ubiE/COQ5 methyltransferase family;
97-285 5.30e-16

ubiE/COQ5 methyltransferase family;


Pssm-ID: 395966 [Multi-domain]  Cd Length: 228  Bit Score: 76.32  E-value: 5.30e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  97 LEGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKHVgystERFGYSkpNLEFFVGYIEKLAEKgigDNS 176
Cdd:pfam01209  41 KRGNKFLDVAGGTGDWTFGLSDSAGSSGKVVGLDINENMLKEGEKKA----KEEGKY--NIEFLQGNAEELPFE---DDS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 177 FNIL-VSNGVINlTSDKKAVLQEAYRVLKEGGELY---FSDVYCskelpEEVRKNEYLWS---MCIAGSLYWKRlhdiAK 249
Cdd:pfam01209 112 FDIVtISFGLRN-FPDYLKVLKEAFRVLKPGGRVVcleFSKPEN-----PLLSQAYELYFkyvMPFMGKMFAKS----YK 181

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2194090446 250 EVGFcvprVVEITTVAINNEEYKTLVGDARFVSITY 285
Cdd:pfam01209 182 SYQY----LQESIRDFPDQKTLASMFEKAGFKSVGY 213
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 99-209 1.12e-15

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 75.57  E-value: 1.12e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  99 GQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKHVgysteRFGYSKPNLEFFVGYIEKLAekgIGDNSFN 178
Cdd:PRK00216   52 GDKVLDLACGTGDLAIALAKAVGKTGEVVGLDFSEGMLAVGREKL-----RDLGLSGNVEFVQGDAEALP---FPDNSFD 123

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2194090446 179 IL-VSNGVINLTsDKKAVLQEAYRVLKEGGEL 209
Cdd:PRK00216  124 AVtIAFGLRNVP-DIDKALREMYRVLKPGGRL 154
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 103-211 1.68e-15

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 71.16  E-value: 1.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 103 LDLGCGAGRDTYIVSKLVGpegSIVGVDMTDALIEVANKHvgysterfgYSKPNLEFFVGYIEKLaekGIGDNSFNILVS 182
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGA---RVTGVDISPEMLELAREK---------APREGLTFVVGDAEDL---PFPDNSFDLVLS 65

                          90       100
                  ....*....|....*....|....*....
gi 2194090446 183 NGVINLTSDKKAVLQEAYRVLKEGGELYF 211
Cdd:pfam08241  66 SEVLHHVEDPERALREIARVLKPGGILII 94
MenG_MenH_UbiE TIGR01934
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ...
 80-253 2.52e-15

ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273884 [Multi-domain]  Cd Length: 223  Bit Score: 74.22  E-value: 2.52e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  80 QDVLDRYYGCGMVIPEKleGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKhvgysteRFGySKPNLEF 159
Cdd:TIGR01934  23 LHRLWRRRAVKLIGVFK--GQKVLDVACGTGDLAIELAKSAPDRGKVTGVDFSSEMLEVAKK-------KSE-LPLNIEF 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 160 FVGYIEKLAEKgigDNSFNIL-VSNGVINLTsDKKAVLQEAYRVLKEGGELY--------------FSDVYCSKELP--- 221
Cdd:TIGR01934  93 IQADAEALPFE---DNSFDAVtIAFGLRNVT-DIQKALREMYRVLKPGGRLVilefskpanallkkFYKFYLKNVLPsig 168

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2194090446 222 EEVRKN----EYLwSMCIAGSLYWKRLHDIAKEVGF 253
Cdd:TIGR01934 169 GLISKNaeayTYL-PESIRAFPSQEELAAMLKEAGF 203
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
98-213 8.01e-14

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 66.77  E-value: 8.01e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  98 EGQKVLDLGCGAGRDTYIVSKLVgPEGSIVGVDMTDALIEVANKHVgysterfgyskPNLEFFVGYIEKLAEKGigdnSF 177
Cdd:COG4106     1 PPRRVLDLGCGTGRLTALLAERF-PGARVTGVDLSPEMLARARARL-----------PNVRFVVADLRDLDPPE----PF 64

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2194090446 178 NILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSD 213
Cdd:COG4106    65 DLVVSNAALHWLPDHAALLARLAAALAPGGVLAVQV 100
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 101-216 8.77e-14

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 67.07  E-value: 8.77e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 101 KVLDLGCGAGRDTYIVSKlvGPEGSIVGVDMTDALIEVANKhvgystERFGYSKPNLEFFVGYIEKLAEKGigDNSFNIL 180
Cdd:cd02440     1 RVLDLGCGTGALALALAS--GPGARVTGVDISPVALELARK------AAAALLADNVEVLKGDAEELPPEA--DESFDVI 70

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2194090446 181 VSNGVIN-LTSDKKAVLQEAYRVLKEGGELYFSDVYC 216
Cdd:cd02440    71 ISDPPLHhLVEDLARFLEEARRLLKPGGVLVLTLVLA 107
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 96-222 9.65e-13

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 67.31  E-value: 9.65e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  96 KLEGQKVLDLGCGAGrdtyIVSKLV---GPEGSIVGVDMTDALIEVANKHVGysterfgyskPNLEFFVGYIEKLAekgI 172
Cdd:TIGR02072  32 IFIPASVLDIGCGTG----YLTRALlkrFPQAEFIALDISAGMLAQAKTKLS----------ENVQFICGDAEKLP---L 94

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2194090446 173 GDNSFNILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSDvYCSKELPE 222
Cdd:TIGR02072  95 EDSSFDLIVSNLALQWCDDLSQALSELARVLKPGGLLAFST-FGPGTLHE 143
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 98-214 1.13e-12

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 66.09  E-value: 1.13e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  98 EGQKVLDLGCGAGRDTYIVSKLVGpeGSIVGVDMTDALIEVANKHVgystERFGYSkpNLEFFVGYIEKLaeKGIGDNSF 177
Cdd:COG0500    26 KGGRVLDLGCGTGRNLLALAARFG--GRVIGIDLSPEAIALARARA----AKAGLG--NVEFLVADLAEL--DPLPAESF 95

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2194090446 178 NILVSNGVINLTSDKK--AVLQEAYRVLKEGGELYFSDV 214
Cdd:COG0500    96 DLVVAFGVLHHLPPEEreALLRELARALKPGGVLLLSAS 134
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
77-212 1.81e-11

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 62.32  E-value: 1.81e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  77 HVHQDVLDRYYGcgmvipekLEGQKVLDLGCGAGRDTYIVSKLVGpegSIVGVDMTDALIEVANKHVGYSterfgyskpn 156
Cdd:COG4976    33 LLAEELLARLPP--------GPFGRVLDLGCGTGLLGEALRPRGY---RLTGVDLSEEMLAKAREKGVYD---------- 91

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2194090446 157 lEFFVGYIEKLAEkgiGDNSFNILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFS 212
Cdd:COG4976    92 -RLLVADLADLAE---PDGRFDLIVAADVLTYLGDLAAVFAGVARALKPGGLFIFS 143
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 103-209 6.13e-11

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 58.53  E-value: 6.13e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 103 LDLGCGAGRDTYIVSKLVgPEGSIVGVDMTDALIEVANKHVGystERFGYSKPNLEFFVGYIEKLAEkgigdNSFNILVS 182
Cdd:pfam08242   1 LEIGCGTGTLLRALLEAL-PGLEYTGLDISPAALEAARERLA---ALGLLNAVRVELFQLDLGELDP-----GSFDVVVA 71

                          90       100
                  ....*....|....*....|....*..
gi 2194090446 183 NGVINLTSDKKAVLQEAYRVLKEGGEL 209
Cdd:pfam08242  72 SNVLHHLADPRAVLRNIRRLLKPGGVL 98
PLN02336 PLN02336
phosphoethanolamine N-methyltransferase
 99-229 9.10e-08

phosphoethanolamine N-methyltransferase


Pssm-ID: 177970 [Multi-domain]  Cd Length: 475  Bit Score: 53.60  E-value: 9.10e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  99 GQKVLDLGCG-AGRDTYIVSKLvgpEGSIVGVDMTDALIEVAnkhvgysTERFGYSKPNLEFFVGyieKLAEKGIGDNSF 177
Cdd:PLN02336  267 GQKVLDVGCGiGGGDFYMAENF---DVHVVGIDLSVNMISFA-------LERAIGRKCSVEFEVA---DCTKKTYPDNSF 333

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2194090446 178 NILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSDvYC------SKELPEEVRKNEY 229
Cdd:PLN02336  334 DVIYSRDTILHIQDKPALFRSFFKWLKPGGKVLISD-YCrspgtpSPEFAEYIKQRGY 390
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 94-253 1.01e-07

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 51.27  E-value: 1.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  94 PEKLEGQKVLDLGCGAGrdtyIVSKLVGPEG-SIVGVDMTDALIEVANKHVgysterfgyskpnleFFVGYIEKLAEKgi 172
Cdd:pfam13489  18 PKLPSPGRVLDFGCGTG----IFLRLLRAQGfSVTGVDPSPIAIERALLNV---------------RFDQFDEQEAAV-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 173 GDNSFNILVSNGVINLTSDKKAVLQEAYRVLKEGGELYFSDVYCSKELPEEVRKNEYLWSMCIAGSLYWKR-LHDIAKEV 251
Cdd:pfam13489  77 PAGKFDVIVAREVLEHVPDPPALLRQIAALLKPGGLLLLSTPLASDEADRLLLEWPYLRPRNGHISLFSARsLKRLLEEA 156


                  ..
gi 2194090446 252 GF 253
Cdd:pfam13489 157 GF 158
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 93-211 1.77e-07

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 50.96  E-value: 1.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  93 IPEKLEGqKVLDLGCGAGrdtYI--VSKLVGPEGSIVGVDMTDALIEVANKHVgystERFGYskPNLEFFVGYieklAEK 170
Cdd:COG2813    45 LPEPLGG-RVLDLGCGYG---VIglALAKRNPEARVTLVDVNARAVELARANA----AANGL--ENVEVLWSD----GLS 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2194090446 171 GIGDNSFNILVSN-----GVinlTSDKKAV---LQEAYRVLKEGGELYF 211
Cdd:COG2813   111 GVPDGSFDLILSNppfhaGR---AVDKEVAhalIADAARHLRPGGELWL 156
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 93-213 2.82e-06

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 46.85  E-value: 2.82e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  93 IPEKLE---GQKVLDLGCGAGRDTYIVSKLVGpeGSIVGVDMTDALIEVANKHVgystERFGYSkPNLEFFVGYIEKLAE 169
Cdd:COG2230    43 ILRKLGlkpGMRVLDIGCGWGGLALYLARRYG--VRVTGVTLSPEQLEYARERA----AEAGLA-DRVEVRLADYRDLPA 115

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2194090446 170 KGigdnSFNILVSNGVINLTSDKK--AVLQEAYRVLKEGGELYFSD 213
Cdd:COG2230   116 DG----QFDAIVSIGMFEHVGPENypAYFAKVARLLKPGGRLLLHT 157
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
98-209 7.41e-06

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 46.21  E-value: 7.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  98 EGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKHVgystERFGYSkpNLEFFVGYieklAEKGIGDNS- 176
Cdd:pfam01135  73 PGMRVLEIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRNL----EKLGLE--NVIVVVGD----GRQGWPEFAp 142

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2194090446 177 FNilvsngVINLTSDKKAVLQEAYRVLKEGGEL 209
Cdd:pfam01135 143 YD------AIHVGAAAPEIPEALIDQLKEGGRL 169
PLN02233 PLN02233
ubiquinone biosynthesis methyltransferase
 99-261 1.76e-05

ubiquinone biosynthesis methyltransferase


Pssm-ID: 177877 [Multi-domain]  Cd Length: 261  Bit Score: 45.65  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  99 GQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKHvgySTERFGYSKPNLEFFVGYIEKLAekgIGDNSFN 178
Cdd:PLN02233   74 GDRVLDLCCGSGDLAFLLSEKVGSDGKVMGLDFSSEQLAVAASR---QELKAKSCYKNIEWIEGDATDLP---FDDCYFD 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 179 -ILVSNGVINLTSDKKAVlQEAYRVLKEGGELYFSDVYCSKE-----------------------LPEEVrknEYLWSmC 234
Cdd:PLN02233  148 aITMGYGLRNVVDRLKAM-QEMYRVLKPGSRVSILDFNKSTQpfttsmqewmidnvvvpvatgygLAKEY---EYLKS-S 222

                         170       180
                  ....*....|....*....|....*..
gi 2194090446 235 IAGSLYWKRLHDIAKEVGFCVPRVVEI 261
Cdd:PLN02233  223 INEYLTGEELEKLALEAGFSSAKHYEI 249
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 99-261 1.54e-04

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 42.84  E-value: 1.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  99 GQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKHVgystERFGYSkPNLEFFVGYIeklaEKGIGDNSFN 178
Cdd:COG2519    92 GARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNL----ERFGLP-DNVELKLGDI----REGIDEGDVD 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446 179 ILVsngvinLtsDKKA---VLQEAYRVLKEGGelYFSdVYCskelP--EEVrkneylwsmciagslywKRLHDIAKEVGF 253
Cdd:COG2519   163 AVF------L--DMPDpweALEAVAKALKPGG--VLV-AYV----PtvNQV-----------------SKLVEALRESGF 210


                  ....*...
gi 2194090446 254 CVPRVVEI 261
Cdd:COG2519   211 TDIEAVET 218
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 99-211 7.94e-04

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 40.51  E-value: 7.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  99 GQKVLDLGCGAGrdtyIVSKLV---GPEGSIVGVDMTDALIEVANKHVGYS--TERfgyskpnLEFFVGYIEKLAEKgIG 173
Cdd:COG4123    38 GGRVLDLGTGTG----VIALMLaqrSPGARITGVEIQPEAAELARRNVALNglEDR-------ITVIHGDLKEFAAE-LP 105

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2194090446 174 DNSFNILVSN--------GVINLTSDK-----------KAVLQEAYRVLKEGGELYF 211
Cdd:COG4123   106 PGSFDLVVSNppyfkagsGRKSPDEARaiarhedaltlEDLIRAAARLLKPGGRFAL 162
PTZ00098 PTZ00098
phosphoethanolamine N-methyltransferase; Provisional
 98-229 8.08e-04

phosphoethanolamine N-methyltransferase; Provisional


Pssm-ID: 173391 [Multi-domain]  Cd Length: 263  Bit Score: 40.72  E-value: 8.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  98 EGQKVLDLGCGAGRDTYIVSKLVGpeGSIVGVDMTDALIEVANKHVGysterfgySKPNLEFFVGYIEKlaeKGIGDNSF 177
Cdd:PTZ00098   52 ENSKVLDIGSGLGGGCKYINEKYG--AHVHGVDICEKMVNIAKLRNS--------DKNKIEFEANDILK---KDFPENTF 118

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2194090446 178 NILVS-NGVINLT-SDKKAVLQEAYRVLKEGGELYFSDvYCS-------KELPEEVRKNEY 229
Cdd:PTZ00098  119 DMIYSrDAILHLSyADKKKLFEKCYKWLKPNGILLITD-YCAdkienwdEEFKAYIKKRKY 178
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 95-211 9.88e-04

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 39.50  E-value: 9.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  95 EKLEGQKVLDLGCGAGrdtYI--VSKLVGPEGSIVGVDMTDALIEVAnkhvgysteRFGYSKPNLEFFVGYIEKLAEkGI 172
Cdd:pfam05175  28 PKDLSGKVLDLGCGAG---VLgaALAKESPDAELTMVDINARALESA---------RENLAANGLENGEVVASDVYS-GV 94

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2194090446 173 GDNSFNILVSN-----GVINLTSDKKAVLQEAYRVLKEGGELYF 211
Cdd:pfam05175  95 EDGKFDLIISNppfhaGLATTYNVAQRFIADAKRHLRPGGELWI 138
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
97-141 1.56e-03

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 39.50  E-value: 1.56e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2194090446  97 LEGQKVLDLGCGAGRDTYIvSKLVGPEgSIVGVDMTDALIEVANK 141
Cdd:COG2263    44 IEGKTVLDLGCGTGMLAIG-AALLGAK-KVVGVDIDPEALEIARE 86
PRK13942 PRK13942
protein-L-isoaspartate O-methyltransferase; Provisional
 98-162 3.23e-03

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 184409  Cd Length: 212  Bit Score: 38.46  E-value: 3.23e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2194090446  98 EGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDMTDALIEVANKHVgystERFGYSkpNLEFFVG 162
Cdd:PRK13942   76 EGMKVLEIGTGSGYHAAVVAEIVGKSGKVVTIERIPELAEKAKKTL----KKLGYD--NVEVIVG 134
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
97-226 5.56e-03

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 38.21  E-value: 5.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  97 LEGQKVLDLGCG----AgrdtyIVSKLVGPeGSIVGVDmTDAL-IEVANKHVgystERFGyskpnleffvgyIEKLAEKG 171
Cdd:PRK00517  118 LPGKTVLDVGCGsgilA-----IAAAKLGA-KKVLAVD-IDPQaVEAARENA----ELNG------------VELNVYLP 174

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2194090446 172 IGDNSFNILVSN---GVInltsdkKAVLQEAYRVLKEGGELYFSDVYCSKElpEEVRK 226
Cdd:PRK00517  175 QGDLKADVIVANilaNPL------LELAPDLARLLKPGGRLILSGILEEQA--DEVLE 224
RlmE COG0293
23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ [Translation, ribosomal structure and ...
 98-131 8.01e-03

23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ [Translation, ribosomal structure and biogenesis]; 23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 440062 [Multi-domain]  Cd Length: 208  Bit Score: 37.36  E-value: 8.01e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2194090446  98 EGQKVLDLGCGAGRDTYIVSKLVGPEGSIVGVDM 131
Cdd:COG0293    50 PGMRVVDLGAAPGGWSQVAAKRVGGKGRVIALDL 83
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 97-212 8.52e-03

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 37.63  E-value: 8.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2194090446  97 LEGQKVLDLGCGAGRDTyIVSKLVGPEgSIVGVDMTDALIEVA--NKHVGYSTERFGYSKPNleffvgyiEKLAEKgigd 174
Cdd:pfam06325 160 KPGESVLDVGCGSGILA-IAALKLGAK-KVVGVDIDPVAVRAAkeNAELNGVEARLEVYLPG--------DLPKEK---- 225

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2194090446 175 nsFNILVSN----GVINLTSDkkavlqeAYRVLKEGGELYFS 212
Cdd:pfam06325 226 --ADVVVANiladPLIELAPD-------IYALVKPGGYLILS 258
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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