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Conserved domains on  [gi|2092204041|ref|XP_043357257|]
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LOW QUALITY PROTEIN: host cell factor 1 [Dermochelys coriacea]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
48-367 7.32e-20

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 91.76  E-value: 7.32e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041   48 WS--GPVPRPRHGHRAVAIKELIVVFGGGNEG-IVDELHVYNTATNQWfipaVRGDIPPGCAAYGFVC--DGTRLLVFGG 122
Cdd:COG3055      3 WSslPDLPTPRSEAAAALLDGKVYVAGGLSGGsASNSFEVYDPATNTW----SELAPLPGPPRHHAAAvaQDGKLYVFGG 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  123 MVEY---GKYSSDLYELQASRWEWKRLkaktpknGPPPCPRLGHSFSLVGNKCYLFGGlandsedpkNNIPRYLNDLYIL 199
Cdd:COG3055     79 FTGAnpsSTPLNDVYVYDPATNTWTKL-------APMPTPRGGATALLLDGKIYVVGG---------WDDGGNVAWVEVY 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  200 ELRPGSgvvaWDipiTYGVLPPPRESHTAVVYTErdnkkSKLVIYGGMSGCRLGDLWTldietltwNKPSLsgvaPLPRS 279
Cdd:COG3055    143 DPATGT----WT---QLAPLPTPRDHLAAAVLPD-----GKILVIGGRNGSGFSNTWT--------TLAPL----PTARA 198

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  280 LHSATTIGNKMYVFGGwvplvmddvkvathekEWKCTNTLACLNLDSMAWEPIlmdtleDNIPRARAGHCAVSINTRLYI 359
Cdd:COG3055    199 GHAAAVLGGKILVFGG----------------ESGFSDEVEAYDPATNTWTAL------GELPTPRHGHAAVLTDGKVYV 256

                          330
                   ....*....|
gi 2092204041  360 WSG--RDGYR 367
Cdd:COG3055    257 IGGetKPGVR 266
DUF5585 super family cl39316
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 474-837 5.01e-05

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


The actual alignment was detected with superfamily member pfam17823:

Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 48.03  E-value: 5.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  474 AAPTPTTTIQLLPSVPGTPLPVASPARTQGVPAV----LKVTGPQAPPGPPLVTVRSAGqaGKAPVTVTSLPAgvrmvVP 549
Cdd:pfam17823   46 AVPRADNKSSEQ*NFCAATAAPAPVTLTKGTSAAhlnsTEVTAEHTPHGTDLSEPATRE--GAADGAASRALA-----AA 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  550 TQSTQGTVIGSSPQMSGMAALAAAAAATQKIPPSSApTVLSVPAGATIVKTVAVSPGTATLPSTVKVASAPVMVSNPATR 629
Cdd:pfam17823  119 ASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANA-SAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTT 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  630 MLKTAAAQV----GTSVSST---TNAATRPIITVHKSGTVTVAQQAQVMTTVVGGVTKTITLVKSPISVPGGSALISNLG 702
Cdd:pfam17823  198 AASSAPATLtparGISTAATatgHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHA 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  703 KVMSVVQTKPVQTSAVTGQASSGPvtqiiQTKGPLPAGTILKLVTSADGKPTTIITTTQAGGAGPKPTILGISSVSPSTT 782
Cdd:pfam17823  278 RRLSPAKHMPSDTMARNPAAPMGA-----QAQGPIIQVSTDQPVHNTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTK 352

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2092204041  783 KPGTTTIIKTIPM--SAIITQSGATGVTSSPGIKSPitiittkvmTSGTGAPAKIIT 837
Cdd:pfam17823  353 AQAKEPSASPVPVlhTSMIPEVEATSPTTQPSPLLP---------TQGAAGPGILLA 400
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1711-1754 4.91e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.91e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 2092204041 1711 SGTVPDYTQLKKQELQPGTAYKFRVAGLNACGRGPFSDISAFKT 1754
Cdd:cd00063     50 EVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
1572-1671 6.25e-03

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK14951:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 618  Bit Score: 41.24  E-value: 6.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041 1572 VAQQPHGAPLPTEALAPADSLNDPAAESNGLSELASAVSSTVALLPAAPSEGLAPSNTFVAPQPVVGPSPAKLQAAATLA 1651
Cdd:PRK14951   385 EAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIPV 464

                           90       100
                   ....*....|....*....|
gi 2092204041 1652 EVANGIEPAPMKPDPSVQPQ 1671
Cdd:PRK14951   465 RVAPEPAVASAAPAPAAAPA 484
FN3 super family cl21522
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1761-1863 6.48e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


The actual alignment was detected with superfamily member pfam00041:

Pssm-ID: 473895 [Multi-domain]  Cd Length: 85  Bit Score: 37.39  E-value: 6.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041 1761 GAPCAIKIS-KSPDGAHLTWEPPSVTSGKIVEYSVYLAIQSTQAGEPKGTAPaqlafmrvycGPSPSCLVQsgSLaNAHI 1839
Cdd:pfam00041    1 SAPSNLTVTdVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVP----------GTTTSVTLT--GL-KPGT 67

                           90       100
                   ....*....|....*....|....
gi 2092204041 1840 DYTtkpaiiFRIAARNEKGYGPAT 1863
Cdd:pfam00041   68 EYE------VRVQAVNGGGEGPPS 85
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 718-989 9.02e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.06  E-value: 9.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  718 VTGQASSGPVTQIIQTKGPLPAGTI--LKLVTSADG--------------KPTTIITTTQAGGAGPKPtilGISSVSPST 781
Cdd:pfam05109  458 LTAPASTGPTVSTADVTSPTPAGTTsgASPVTPSPSprdngteskapdmtSPTSAVTTPTPNATSPTP---AVTTPTPNA 534

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  782 TKPgttTIIKTIPMSAIITQS-GATGVTSSPGIKSPITIITTKVMTSGTGA---PAKIITAvPKLGTAHGQQGVTQVVLK 857
Cdd:pfam05109  535 TSP---TLGKTSPTSAVTTPTpNATSPTPAVTTPTPNATIPTLGKTSPTSAvttPTPNATS-PTVGETSPQANTTNHTLG 610

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  858 GAPGQPgtILRTVPMGGVRLVTPVTVSAVKPTVTTLVVKGTTGVTTLGTVTGTVSTSLAG--AGGHST---NASLATPIT 932
Cdd:pfam05109  611 GTSSTP--VVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPllTSAHPTggeNITQVTPAS 688

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2092204041  933 TLGTIATLSSQVINPAAITVSAAQTTMTAASGLGTPTITMQpvSQPTQVTLITTPSG 989
Cdd:pfam05109  689 TSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKG--TPPKNATSPQAPSG 743
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
48-367 7.32e-20

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 91.76  E-value: 7.32e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041   48 WS--GPVPRPRHGHRAVAIKELIVVFGGGNEG-IVDELHVYNTATNQWfipaVRGDIPPGCAAYGFVC--DGTRLLVFGG 122
Cdd:COG3055      3 WSslPDLPTPRSEAAAALLDGKVYVAGGLSGGsASNSFEVYDPATNTW----SELAPLPGPPRHHAAAvaQDGKLYVFGG 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  123 MVEY---GKYSSDLYELQASRWEWKRLkaktpknGPPPCPRLGHSFSLVGNKCYLFGGlandsedpkNNIPRYLNDLYIL 199
Cdd:COG3055     79 FTGAnpsSTPLNDVYVYDPATNTWTKL-------APMPTPRGGATALLLDGKIYVVGG---------WDDGGNVAWVEVY 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  200 ELRPGSgvvaWDipiTYGVLPPPRESHTAVVYTErdnkkSKLVIYGGMSGCRLGDLWTldietltwNKPSLsgvaPLPRS 279
Cdd:COG3055    143 DPATGT----WT---QLAPLPTPRDHLAAAVLPD-----GKILVIGGRNGSGFSNTWT--------TLAPL----PTARA 198

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  280 LHSATTIGNKMYVFGGwvplvmddvkvathekEWKCTNTLACLNLDSMAWEPIlmdtleDNIPRARAGHCAVSINTRLYI 359
Cdd:COG3055    199 GHAAAVLGGKILVFGG----------------ESGFSDEVEAYDPATNTWTAL------GELPTPRHGHAAVLTDGKVYV 256

                          330
                   ....*....|
gi 2092204041  360 WSG--RDGYR 367
Cdd:COG3055    257 IGGetKPGVR 266
PLN02193 PLN02193
nitrile-specifier protein
 50-345 8.43e-15

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 79.23  E-value: 8.43e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041   50 GPVPRPRHGHRAVAIKelIVVFGGG---NEGIVDELHVYNTATNQWFIPAVRGDIPP-GCAAYGFVCDGTRLLVFGGMVE 125
Cdd:PLN02193   162 GPGLRCSHGIAQVGNK--IYSFGGEftpNQPIDKHLYVFDLETRTWSISPATGDVPHlSCLGVRMVSIGSTLYVFGGRDA 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  126 YGKYSSdLYELQASRWEWKRLkakTP-KNGppPCPRLGHSFSLVGNKCYLFGGLANDSEdpknniPRYLNDLYILELRpg 204
Cdd:PLN02193   240 SRQYNG-FYSFDTTTNEWKLL---TPvEEG--PTPRSFHSMAADEENVYVFGGVSATAR------LKTLDSYNIVDKK-- 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  205 sgvvaWDIPITygvlppPRESHTAVVYTERDNKKSKLVIYGGMSGCRLGDLWTLDIETLTWNKPSLSGVAPLPRSLHSAT 284
Cdd:PLN02193   306 -----WFHCST------PGDSFSIRGGAGLEVVQGKVWVVYGFNGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASA 374

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2092204041  285 TIGNKMYVFGGwvPLVMDDVkvaTHEKEWKCTNTLACLNLDSMAWEPILMDTLEDNIPRAR 345
Cdd:PLN02193   375 AVGKHIVIFGG--EIAMDPL---AHVGPGQLTDGTFALDTETLQWERLDKFGEEEETPSSR 430
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 474-837 5.01e-05

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 48.03  E-value: 5.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  474 AAPTPTTTIQLLPSVPGTPLPVASPARTQGVPAV----LKVTGPQAPPGPPLVTVRSAGqaGKAPVTVTSLPAgvrmvVP 549
Cdd:pfam17823   46 AVPRADNKSSEQ*NFCAATAAPAPVTLTKGTSAAhlnsTEVTAEHTPHGTDLSEPATRE--GAADGAASRALA-----AA 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  550 TQSTQGTVIGSSPQMSGMAALAAAAAATQKIPPSSApTVLSVPAGATIVKTVAVSPGTATLPSTVKVASAPVMVSNPATR 629
Cdd:pfam17823  119 ASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANA-SAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTT 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  630 MLKTAAAQV----GTSVSST---TNAATRPIITVHKSGTVTVAQQAQVMTTVVGGVTKTITLVKSPISVPGGSALISNLG 702
Cdd:pfam17823  198 AASSAPATLtparGISTAATatgHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHA 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  703 KVMSVVQTKPVQTSAVTGQASSGPvtqiiQTKGPLPAGTILKLVTSADGKPTTIITTTQAGGAGPKPTILGISSVSPSTT 782
Cdd:pfam17823  278 RRLSPAKHMPSDTMARNPAAPMGA-----QAQGPIIQVSTDQPVHNTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTK 352

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2092204041  783 KPGTTTIIKTIPM--SAIITQSGATGVTSSPGIKSPitiittkvmTSGTGAPAKIIT 837
Cdd:pfam17823  353 AQAKEPSASPVPVlhTSMIPEVEATSPTTQPSPLLP---------TQGAAGPGILLA 400
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 55-92 1.07e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 41.44  E-value: 1.07e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 2092204041   55 PRHGHRAVAIKELIVVFGGGNEG-IVDELHVYNTATNQW 92
Cdd:pfam01344    1 RRSGAGVVVVGGKIYVIGGFDGNqSLNSVEVYDPETNTW 39
PHA03255 PHA03255
BDLF3; Provisional
 704-842 3.14e-03

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 41.43  E-value: 3.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  704 VMSVVQTKPVQTSAVTGQASSGPVTQIIQTKGPLPAGTILKLVTSADGKPTTI-ITTTQAGGAGPKPTILGISSVSPSTT 782
Cdd:PHA03255    14 MILICETSLIWTSSGSSTASAGNVTGTTAVTTPSPSASGPSTNQSTTLTTTSApITTTAILSTNTTTVTSTGTTVTPVPT 93

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  783 KPGTTTIIKTIPMSAIITQSGATGVTSSPGIKSPITIITTKVmTSGTGAPAKIITAVPKL 842
Cdd:PHA03255    94 TSNASTINVTTKVTAQNITATEAGTGTSTGVTSNVTTRSSST-TSATTRITNATTLAPTL 152
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1711-1754 4.91e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.91e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 2092204041 1711 SGTVPDYTQLKKQELQPGTAYKFRVAGLNACGRGPFSDISAFKT 1754
Cdd:cd00063     50 EVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 1572-1671 6.25e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.24  E-value: 6.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041 1572 VAQQPHGAPLPTEALAPADSLNDPAAESNGLSELASAVSSTVALLPAAPSEGLAPSNTFVAPQPVVGPSPAKLQAAATLA 1651
Cdd:PRK14951   385 EAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIPV 464

                           90       100
                   ....*....|....*....|
gi 2092204041 1652 EVANGIEPAPMKPDPSVQPQ 1671
Cdd:PRK14951   465 RVAPEPAVASAAPAPAAAPA 484
fn3 pfam00041
Fibronectin type III domain;
1761-1863 6.48e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 37.39  E-value: 6.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041 1761 GAPCAIKIS-KSPDGAHLTWEPPSVTSGKIVEYSVYLAIQSTQAGEPKGTAPaqlafmrvycGPSPSCLVQsgSLaNAHI 1839
Cdd:pfam00041    1 SAPSNLTVTdVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVP----------GTTTSVTLT--GL-KPGT 67

                           90       100
                   ....*....|....*....|....
gi 2092204041 1840 DYTtkpaiiFRIAARNEKGYGPAT 1863
Cdd:pfam00041   68 EYE------VRVQAVNGGGEGPPS 85
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1760-1864 8.48e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 37.48  E-value: 8.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041 1760 PGAPCAIKISK-SPDGAHLTWEPPSVTSGKIVEYSVYLaiqstqagepKGTAPAQLAFMRVYCGPSPSCLVQsgSLaNAH 1838
Cdd:cd00063      1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGGPITGYVVEY----------REKGSGDWKEVEVTPGSETSYTLT--GL-KPG 67

                           90       100
                   ....*....|....*....|....*.
gi 2092204041 1839 IDYTtkpaiiFRIAARNEKGYGPATQ 1864
Cdd:cd00063     68 TEYE------FRVRAVNGGGESPPSE 87
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 718-989 9.02e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.06  E-value: 9.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  718 VTGQASSGPVTQIIQTKGPLPAGTI--LKLVTSADG--------------KPTTIITTTQAGGAGPKPtilGISSVSPST 781
Cdd:pfam05109  458 LTAPASTGPTVSTADVTSPTPAGTTsgASPVTPSPSprdngteskapdmtSPTSAVTTPTPNATSPTP---AVTTPTPNA 534

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  782 TKPgttTIIKTIPMSAIITQS-GATGVTSSPGIKSPITIITTKVMTSGTGA---PAKIITAvPKLGTAHGQQGVTQVVLK 857
Cdd:pfam05109  535 TSP---TLGKTSPTSAVTTPTpNATSPTPAVTTPTPNATIPTLGKTSPTSAvttPTPNATS-PTVGETSPQANTTNHTLG 610

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  858 GAPGQPgtILRTVPMGGVRLVTPVTVSAVKPTVTTLVVKGTTGVTTLGTVTGTVSTSLAG--AGGHST---NASLATPIT 932
Cdd:pfam05109  611 GTSSTP--VVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPllTSAHPTggeNITQVTPAS 688

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2092204041  933 TLGTIATLSSQVINPAAITVSAAQTTMTAASGLGTPTITMQpvSQPTQVTLITTPSG 989
Cdd:pfam05109  689 TSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKG--TPPKNATSPQAPSG 743
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
48-367 7.32e-20

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 91.76  E-value: 7.32e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041   48 WS--GPVPRPRHGHRAVAIKELIVVFGGGNEG-IVDELHVYNTATNQWfipaVRGDIPPGCAAYGFVC--DGTRLLVFGG 122
Cdd:COG3055      3 WSslPDLPTPRSEAAAALLDGKVYVAGGLSGGsASNSFEVYDPATNTW----SELAPLPGPPRHHAAAvaQDGKLYVFGG 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  123 MVEY---GKYSSDLYELQASRWEWKRLkaktpknGPPPCPRLGHSFSLVGNKCYLFGGlandsedpkNNIPRYLNDLYIL 199
Cdd:COG3055     79 FTGAnpsSTPLNDVYVYDPATNTWTKL-------APMPTPRGGATALLLDGKIYVVGG---------WDDGGNVAWVEVY 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  200 ELRPGSgvvaWDipiTYGVLPPPRESHTAVVYTErdnkkSKLVIYGGMSGCRLGDLWTldietltwNKPSLsgvaPLPRS 279
Cdd:COG3055    143 DPATGT----WT---QLAPLPTPRDHLAAAVLPD-----GKILVIGGRNGSGFSNTWT--------TLAPL----PTARA 198

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  280 LHSATTIGNKMYVFGGwvplvmddvkvathekEWKCTNTLACLNLDSMAWEPIlmdtleDNIPRARAGHCAVSINTRLYI 359
Cdd:COG3055    199 GHAAAVLGGKILVFGG----------------ESGFSDEVEAYDPATNTWTAL------GELPTPRHGHAAVLTDGKVYV 256

                          330
                   ....*....|
gi 2092204041  360 WSG--RDGYR 367
Cdd:COG3055    257 IGGetKPGVR 266
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
99-368 9.79e-16

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 79.43  E-value: 9.79e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041   99 GDIP-PGCAAYGFVCDGtRLLVFGGMvEYGKYSSDLYELQASRWEWKRLkaktpknGPPPCPRLGHSFSLV-GNKCYLFG 176
Cdd:COG3055      7 PDLPtPRSEAAAALLDG-KVYVAGGL-SGGSASNSFEVYDPATNTWSEL-------APLPGPPRHHAAAVAqDGKLYVFG 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  177 GLandseDPKNNIPRYLNDLYILELRPGSgvvaWdipITYGVLPPPRESHTAVVYterDNKKskLVIYGGMSGCRLGDLW 256
Cdd:COG3055     78 GF-----TGANPSSTPLNDVYVYDPATNT----W---TKLAPMPTPRGGATALLL---DGKI--YVVGGWDDGGNVAWVE 140

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  257 TLDIETLTWNKPslsGVAPLPRSLHSATTIGN-KMYVFGGwvplvmddVKVATHEKEWkctntlaclnldsmawepilmd 335
Cdd:COG3055    141 VYDPATGTWTQL---APLPTPRDHLAAAVLPDgKILVIGG--------RNGSGFSNTW---------------------- 187

                          250       260       270
                   ....*....|....*....|....*....|...
gi 2092204041  336 TLEDNIPRARAGHCAVSINTRLYIWSGRDGYRK 368
Cdd:COG3055    188 TTLAPLPTARAGHAAAVLGGKILVFGGESGFSD 220
PLN02193 PLN02193
nitrile-specifier protein
 50-345 8.43e-15

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 79.23  E-value: 8.43e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041   50 GPVPRPRHGHRAVAIKelIVVFGGG---NEGIVDELHVYNTATNQWFIPAVRGDIPP-GCAAYGFVCDGTRLLVFGGMVE 125
Cdd:PLN02193   162 GPGLRCSHGIAQVGNK--IYSFGGEftpNQPIDKHLYVFDLETRTWSISPATGDVPHlSCLGVRMVSIGSTLYVFGGRDA 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  126 YGKYSSdLYELQASRWEWKRLkakTP-KNGppPCPRLGHSFSLVGNKCYLFGGLANDSEdpknniPRYLNDLYILELRpg 204
Cdd:PLN02193   240 SRQYNG-FYSFDTTTNEWKLL---TPvEEG--PTPRSFHSMAADEENVYVFGGVSATAR------LKTLDSYNIVDKK-- 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  205 sgvvaWDIPITygvlppPRESHTAVVYTERDNKKSKLVIYGGMSGCRLGDLWTLDIETLTWNKPSLSGVAPLPRSLHSAT 284
Cdd:PLN02193   306 -----WFHCST------PGDSFSIRGGAGLEVVQGKVWVVYGFNGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASA 374

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2092204041  285 TIGNKMYVFGGwvPLVMDDVkvaTHEKEWKCTNTLACLNLDSMAWEPILMDTLEDNIPRAR 345
Cdd:PLN02193   375 AVGKHIVIFGG--EIAMDPL---AHVGPGQLTDGTFALDTETLQWERLDKFGEEEETPSSR 430
PLN02153 PLN02153
epithiospecifier protein
 38-353 1.61e-13

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 74.25  E-value: 1.61e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041   38 LQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGG---NEGIVDELHVYNTATNQWFIPAVRGDIPP-GCAAYGFVCD 113
Cdd:PLN02153     5 LQGGWIKVEQKGGKGPGPRCSHGIAVVGDKLYSFGGElkpNEHIDKDLYVFDFNTHTWSIAPANGDVPRiSCLGVRMVAV 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  114 GTRLLVFGGMVEYGKYsSDLYELQASRWEWKRLKAKTPKNGPPpcPRLGHSFSLVGNKCYLFGGLandSEDPKNNIPRYL 193
Cdd:PLN02153    85 GTKLYIFGGRDEKREF-SDFYSYDTVKNEWTFLTKLDEEGGPE--ARTFHSMASDENHVYVFGGV---SKGGLMKTPERF 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  194 NDLYI-----------------LELRPGSG--VVAWDIPITYGVLpppreshTAVVYTERDNKKSKLVIYggmsgcrlgd 254
Cdd:PLN02153   159 RTIEAyniadgkwvqlpdpgenFEKRGGAGfaVVQGKIWVVYGFA-------TSILPGGKSDYESNAVQF---------- 221

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  255 lwtLDIETLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGwvpLVMDDVKvaTHEKEWKCTNTLACLNLDSMAWEPiLM 334
Cdd:PLN02153   222 ---FDPASGKWTEVETTGAKPSARSVFAHAVVGKYIIIFGG---EVWPDLK--GHLGPGTLSNEGYALDTETLVWEK-LG 292

                          330
                   ....*....|....*....
gi 2092204041  335 DTLEDNIPRARAGHCAVSI 353
Cdd:PLN02153   293 ECGEPAMPRGWTAYTTATV 311
PLN02193 PLN02193
nitrile-specifier protein
 149-295 3.48e-08

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 58.04  E-value: 3.48e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  149 KTPKNGPPPCPRLGHSFSLVGNKCYLFGGlandSEDPKNNIPRYlndLYILELRPGSgvvaWDIPITYGVLPppresHTA 228
Cdd:PLN02193   155 KVEQKGEGPGLRCSHGIAQVGNKIYSFGG----EFTPNQPIDKH---LYVFDLETRT----WSISPATGDVP-----HLS 218

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2092204041  229 VVYTERDNKKSKLVIYGGMSGCR-LGDLWTLDIETLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGG 295
Cdd:PLN02193   219 CLGVRMVSIGSTLYVFGGRDASRqYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGG 286
PRK14131 PRK14131
N-acetylneuraminate epimerase;
41-133 1.74e-05

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 49.24  E-value: 1.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041   41 RWKRVVGWSGPvprPRHGHRAVAIKELIVVFGG----GNEG---IVDELHVYNTATNQWFIPAVRGdiPPGCA-AYGFVC 112
Cdd:PRK14131    63 GWTKIAAFPGG---PREQAVAAFIDGKLYVFGGigktNSEGspqVFDDVYKYDPKTNSWQKLDTRS--PVGLAgHVAVSL 137

                           90       100
                   ....*....|....*....|...
gi 2092204041  113 DGTRLLVFGGMVE--YGKYSSDL 133
Cdd:PRK14131   138 HNGKAYITGGVNKniFDGYFEDL 160
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 474-837 5.01e-05

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 48.03  E-value: 5.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  474 AAPTPTTTIQLLPSVPGTPLPVASPARTQGVPAV----LKVTGPQAPPGPPLVTVRSAGqaGKAPVTVTSLPAgvrmvVP 549
Cdd:pfam17823   46 AVPRADNKSSEQ*NFCAATAAPAPVTLTKGTSAAhlnsTEVTAEHTPHGTDLSEPATRE--GAADGAASRALA-----AA 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  550 TQSTQGTVIGSSPQMSGMAALAAAAAATQKIPPSSApTVLSVPAGATIVKTVAVSPGTATLPSTVKVASAPVMVSNPATR 629
Cdd:pfam17823  119 ASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANA-SAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTT 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  630 MLKTAAAQV----GTSVSST---TNAATRPIITVHKSGTVTVAQQAQVMTTVVGGVTKTITLVKSPISVPGGSALISNLG 702
Cdd:pfam17823  198 AASSAPATLtparGISTAATatgHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHA 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  703 KVMSVVQTKPVQTSAVTGQASSGPvtqiiQTKGPLPAGTILKLVTSADGKPTTIITTTQAGGAGPKPTILGISSVSPSTT 782
Cdd:pfam17823  278 RRLSPAKHMPSDTMARNPAAPMGA-----QAQGPIIQVSTDQPVHNTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTK 352

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2092204041  783 KPGTTTIIKTIPM--SAIITQSGATGVTSSPGIKSPitiittkvmTSGTGAPAKIIT 837
Cdd:pfam17823  353 AQAKEPSASPVPVlhTSMIPEVEATSPTTQPSPLLP---------TQGAAGPGILLA 400
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
50-137 6.82e-05

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 46.69  E-value: 6.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041   50 GPVPRPRHGHRAVAIKELIVVFGGGNeGIVDELHVYNTATNQWFipaVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKY 129
Cdd:COG3055    191 APLPTARAGHAAAVLGGKILVFGGES-GFSDEVEAYDPATNTWT---ALGELPTPRHGHAAVLTDGKVYVIGGETKPGVR 266


                   ....*...
gi 2092204041  130 SSDLYELQ 137
Cdd:COG3055    267 TPLVTSAE 274
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 55-92 1.07e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 41.44  E-value: 1.07e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 2092204041   55 PRHGHRAVAIKELIVVFGGGNEG-IVDELHVYNTATNQW 92
Cdd:pfam01344    1 RRSGAGVVVVGGKIYVIGGFDGNqSLNSVEVYDPETNTW 39
PLN02193 PLN02193
nitrile-specifier protein
 265-425 2.67e-04

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 45.72  E-value: 2.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  265 WNKPSLSGVAPLPRSLHSATTIGNKMYVFGG-WVPlvmdDVKVATHekewkctntLACLNLDSMAWEpilMDTLEDNIPR 343
Cdd:PLN02193   153 WIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGeFTP----NQPIDKH---------LYVFDLETRTWS---ISPATGDVPH 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  344 ARA-GHCAVSINTRLYIWSGRDGYRK--AWNNQVCCKDLWYLET--EKPPAPSRVQLVRANTNSLEVsWGSVpTADTYLL 418
Cdd:PLN02193   217 LSClGVRMVSIGSTLYVFGGRDASRQynGFYSFDTTTNEWKLLTpvEEGPTPRSFHSMAADEENVYV-FGGV-SATARLK 294


                   ....*..
gi 2092204041  419 QLQKYDI 425
Cdd:PLN02193   295 TLDSYNI 301
Kelch_3 pfam13415
Galactose oxidase, central domain;
287-353 9.08e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 38.81  E-value: 9.08e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2092204041  287 GNKMYVFGGWVPLVMDdvkvathekewkCTNTLACLNLDSMAWEPIlmdtleDNIPRARAGHCAVSI 353
Cdd:pfam13415    1 GDKLYIFGGLGFDGQT------------RLNDLYVYDLDTNTWTQI------GDLPPPRSGHSATYI 49
Kelch_3 pfam13415
Galactose oxidase, central domain;
238-286 9.17e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 38.81  E-value: 9.17e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2092204041  238 KSKLVIYGG---MSGCRLGDLWTLDIETLTWNKPslsGVAPLPRSLHSATTI 286
Cdd:pfam13415    1 GDKLYIFGGlgfDGQTRLNDLYVYDLDTNTWTQI---GDLPPPRSGHSATYI 49
Kelch_4 pfam13418
Galactose oxidase, central domain;
55-103 1.25e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 38.36  E-value: 1.25e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2092204041   55 PRHGHRAVAIKE-LIVVFGG--GNEGIVDELHVYNTATNQWfipAVRGDIPP 103
Cdd:pfam13418    1 PRAYHTSTSIPDdTIYLFGGegEDGTLLSDLWVFDLSTNEW---TRLGSLPS 49
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
264-371 2.29e-03

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 42.07  E-value: 2.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  264 TWNK-PSLsgvaPLPRSLHSATTIGNKMYVFGGWvplvmddvkvatheKEWKCTNTLACLNLDSMAWEPIlmdtleDNIP 342
Cdd:COG3055      2 TWSSlPDL----PTPRSEAAAALLDGKVYVAGGL--------------SGGSASNSFEVYDPATNTWSEL------APLP 57

                           90       100       110
                   ....*....|....*....|....*....|
gi 2092204041  343 RARAGH-CAVSINTRLYIWSGRDGYRKAWN 371
Cdd:COG3055     58 GPPRHHaAAVAQDGKLYVFGGFTGANPSST 87
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 53-90 2.53e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 37.16  E-value: 2.53e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 2092204041   53 PRPRHGHRAVAIKELIVVFGG---GNEGIVDELHVYNTATN 90
Cdd:pfam13854    1 PVPRYGHCAVTVGDYIYLYGGytgGEGQPSDDVYVLSLPTF 41
PHA03255 PHA03255
BDLF3; Provisional
 704-842 3.14e-03

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 41.43  E-value: 3.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  704 VMSVVQTKPVQTSAVTGQASSGPVTQIIQTKGPLPAGTILKLVTSADGKPTTI-ITTTQAGGAGPKPTILGISSVSPSTT 782
Cdd:PHA03255    14 MILICETSLIWTSSGSSTASAGNVTGTTAVTTPSPSASGPSTNQSTTLTTTSApITTTAILSTNTTTVTSTGTTVTPVPT 93

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  783 KPGTTTIIKTIPMSAIITQSGATGVTSSPGIKSPITIITTKVmTSGTGAPAKIITAVPKL 842
Cdd:PHA03255    94 TSNASTINVTTKVTAQNITATEAGTGTSTGVTSNVTTRSSST-TSATTRITNATTLAPTL 152
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1711-1754 4.91e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.91e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 2092204041 1711 SGTVPDYTQLKKQELQPGTAYKFRVAGLNACGRGPFSDISAFKT 1754
Cdd:cd00063     50 EVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 1572-1671 6.25e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.24  E-value: 6.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041 1572 VAQQPHGAPLPTEALAPADSLNDPAAESNGLSELASAVSSTVALLPAAPSEGLAPSNTFVAPQPVVGPSPAKLQAAATLA 1651
Cdd:PRK14951   385 EAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIPV 464

                           90       100
                   ....*....|....*....|
gi 2092204041 1652 EVANGIEPAPMKPDPSVQPQ 1671
Cdd:PRK14951   465 RVAPEPAVASAAPAPAAAPA 484
fn3 pfam00041
Fibronectin type III domain;
1761-1863 6.48e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 37.39  E-value: 6.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041 1761 GAPCAIKIS-KSPDGAHLTWEPPSVTSGKIVEYSVYLAIQSTQAGEPKGTAPaqlafmrvycGPSPSCLVQsgSLaNAHI 1839
Cdd:pfam00041    1 SAPSNLTVTdVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVP----------GTTTSVTLT--GL-KPGT 67

                           90       100
                   ....*....|....*....|....
gi 2092204041 1840 DYTtkpaiiFRIAARNEKGYGPAT 1863
Cdd:pfam00041   68 EYE------VRVQAVNGGGEGPPS 85
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 342-374 8.16e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 36.00  E-value: 8.16e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2092204041  342 PRARAGHCAVSINTRLYIWSGRDGYRKAWNNQV 374
Cdd:pfam13854    1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQPSDDV 33
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 473-815 8.36e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.06  E-value: 8.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  473 AAAPTPTTTIQLLPSVPgtplpVASPARTQGVPAVLKVTGPQAPPGPPLVTVRSAGQAGKAPVTVTSlpaGVRMVVPTQS 552
Cdd:pfam05109  422 SKAPESTTTSPTLNTTG-----FAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTPAGTTS---GASPVTPSPS 493

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  553 TQGTviGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGATIVKTVAVSPGTATLPSTVKVASAPVMVSNPatrmlk 632
Cdd:pfam05109  494 PRDN--GTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTP------ 565

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  633 TAAAQVGT-SVSSTTNAATRPIITVHKSGTVTVAQQAQVMTTVVGGVTKTITLVKSPIS-----VPGGSALISNLGKVMS 706
Cdd:pfam05109  566 TPNATIPTlGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNatsavTTGQHNITSSSTSSMS 645

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  707 VVQTKPVQTSAVTGQASSGPVTQIIQTKGPlPAGTILKLVTSADGKPTTIITTTQAGGAGPKPTILGISSvSPSTTKPGT 786
Cdd:pfam05109  646 LRPSSISETLSPSTSDNSTSHMPLLTSAHP-TGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPGN-SSTSTKPGE 723

                          330       340       350
                   ....*....|....*....|....*....|
gi 2092204041  787 TTIIK-TIPMSAIITQSGATGVTSSPGIKS 815
Cdd:pfam05109  724 VNVTKgTPPKNATSPQAPSGQKTAVPTVTS 753
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1760-1864 8.48e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 37.48  E-value: 8.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041 1760 PGAPCAIKISK-SPDGAHLTWEPPSVTSGKIVEYSVYLaiqstqagepKGTAPAQLAFMRVYCGPSPSCLVQsgSLaNAH 1838
Cdd:cd00063      1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGGPITGYVVEY----------REKGSGDWKEVEVTPGSETSYTLT--GL-KPG 67

                           90       100
                   ....*....|....*....|....*.
gi 2092204041 1839 IDYTtkpaiiFRIAARNEKGYGPATQ 1864
Cdd:cd00063     68 TEYE------FRVRAVNGGGESPPSE 87
Kelch_4 pfam13418
Galactose oxidase, central domain;
222-277 8.54e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 36.05  E-value: 8.54e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2092204041  222 PRESHTAVVyterdNKKSKLVIYGGMS--GCRLGDLWTLDIETLTWNKpslsgVAPLP 277
Cdd:pfam13418    1 PRAYHTSTS-----IPDDTIYLFGGEGedGTLLSDLWVFDLSTNEWTR-----LGSLP 48
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 718-989 9.02e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.06  E-value: 9.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  718 VTGQASSGPVTQIIQTKGPLPAGTI--LKLVTSADG--------------KPTTIITTTQAGGAGPKPtilGISSVSPST 781
Cdd:pfam05109  458 LTAPASTGPTVSTADVTSPTPAGTTsgASPVTPSPSprdngteskapdmtSPTSAVTTPTPNATSPTP---AVTTPTPNA 534

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  782 TKPgttTIIKTIPMSAIITQS-GATGVTSSPGIKSPITIITTKVMTSGTGA---PAKIITAvPKLGTAHGQQGVTQVVLK 857
Cdd:pfam05109  535 TSP---TLGKTSPTSAVTTPTpNATSPTPAVTTPTPNATIPTLGKTSPTSAvttPTPNATS-PTVGETSPQANTTNHTLG 610

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  858 GAPGQPgtILRTVPMGGVRLVTPVTVSAVKPTVTTLVVKGTTGVTTLGTVTGTVSTSLAG--AGGHST---NASLATPIT 932
Cdd:pfam05109  611 GTSSTP--VVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPllTSAHPTggeNITQVTPAS 688

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2092204041  933 TLGTIATLSSQVINPAAITVSAAQTTMTAASGLGTPTITMQpvSQPTQVTLITTPSG 989
Cdd:pfam05109  689 TSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKG--TPPKNATSPQAPSG 743
PHA03098 PHA03098
kelch-like protein; Provisional
 61-318 9.59e-03

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 40.91  E-value: 9.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041   61 AVAIKELIVVFGGGNEG--IVDELHVYNTATNQWF-IPavrgDIPPGCAAYGFVCDGTRLLVFGGmVEYGKYSSDLYELQ 137
Cdd:PHA03098   290 SVVLNNVIYFIGGMNKNnlSVNSVVSYDTKTKSWNkVP----ELIYPRKNPGVTVFNNRIYVIGG-IYNSISLNTVESWK 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  138 ASRWEWKRLKaktpkngPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNnIPRYlnDLYILELRPGSGvvawdipityg 217
Cdd:PHA03098   365 PGESKWREEP-------PLIFPRYNPCVVNVNNLIYVIGGISKNDELLKT-VECF--SLNTNKWSKGSP----------- 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092204041  218 vLPPPRESHTAVVYterdnkKSKLVIYGGMS----GCRLGDLWTLDIETLTWNKPSLSGVaplPRSLHSATTIGNKMYVF 293
Cdd:PHA03098   424 -LPISHYGGCAIYH------DGKIYVIGGISyidnIKVYNIVESYNPVTNKWTELSSLNF---PRINASLCIFNNKIYVV 493

                          250       260
                   ....*....|....*....|....*
gi 2092204041  294 GGWvplvMDDVKVATHEKEWKCTNT 318
Cdd:PHA03098   494 GGD----KYEYYINEIEVYDDKTNT 514
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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