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Conserved domains on  [gi|2008076678|ref|XP_040056298|]
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ubiquinone biosynthesis monooxygenase COQ6, mitochondrial [Gasterosteus aculeatus aculeatus]

Protein Classification

Rossmann-fold NAD(P)-binding domain-containing protein( domain architecture ID 229380)

Rossmann-fold NAD(P)-binding domain-containing protein may function as an oxidoreductase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NADB_Rossmann super family cl21454
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ...
 49-477 0e+00

Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.


The actual alignment was detected with superfamily member TIGR01989:

Pssm-ID: 473865 [Multi-domain]  Cd Length: 437  Bit Score: 571.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSLGMDRNLEGKKILLLEAGNKK-----VMHKVPDTYSTRVSSISPGSATLLTGVGAWEHITKM 123
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPklksrNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 124 RCKPYKRMQVWDACSDVLITFDKEDMQDEMAHIVENDVVVAALTKQLDD-LSDNVQVKYRSKVVKYSWPMPHQQANaIPW 202
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNGKEDMACIIENDNIQNSLYNRLQEyNGDNVKILNPARLISVTIPSKYPNDN-SNW 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 203 VKVTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPTENNVAWQRFLPSGPIAMLPLSDTESS 282
Cdd:TIGR01989 160 VHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNST 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 283 LVWSTSHQQAQELLELDEESFVDAINSAF---WSNENQSELIETAGSLFRSTLSAIMPSAGSPRQLPPSVAGIGPKSRVK 359
Cdd:TIGR01989 240 LVWSTSPEEALRLLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 360 FPLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMA 439
Cdd:TIGR01989 320 FPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLG 399

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 2008076678 440 AIDLMKRLYSTNAAPVVLLRTFGLQATNMVPALKEQIM 477
Cdd:TIGR01989 400 LVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 49-477 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 571.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSLGMDRNLEGKKILLLEAGNKK-----VMHKVPDTYSTRVSSISPGSATLLTGVGAWEHITKM 123
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPklksrNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 124 RCKPYKRMQVWDACSDVLITFDKEDMQDEMAHIVENDVVVAALTKQLDD-LSDNVQVKYRSKVVKYSWPMPHQQANaIPW 202
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNGKEDMACIIENDNIQNSLYNRLQEyNGDNVKILNPARLISVTIPSKYPNDN-SNW 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 203 VKVTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPTENNVAWQRFLPSGPIAMLPLSDTESS 282
Cdd:TIGR01989 160 VHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNST 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 283 LVWSTSHQQAQELLELDEESFVDAINSAF---WSNENQSELIETAGSLFRSTLSAIMPSAGSPRQLPPSVAGIGPKSRVK 359
Cdd:TIGR01989 240 LVWSTSPEEALRLLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 360 FPLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMA 439
Cdd:TIGR01989 320 FPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLG 399

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 2008076678 440 AIDLMKRLYSTNAAPVVLLRTFGLQATNMVPALKEQIM 477
Cdd:TIGR01989 400 LVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
PRK07364 PRK07364
FAD-dependent hydroxylase;
49-473 9.94e-83

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 261.88  E-value: 9.94e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSLgmdRNlEGKKILLLEAGNKKVMHKVPDTYStrvssISPGSATLLTGVGAWEHItKMRCKPY 128
Cdd:PRK07364   19 YDVAIVGGGIVGLTLAAAL---KD-SGLRIALIEAQPAEAAAAKGQAYA-----LSLLSARIFEGIGVWEKI-LPQIGKF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 129 KRMQVWDACSDVLITFDKEDM-QDEMAHIVENDVVVAALTKQLDDLsDNVQVKYRSKVVKYswpmpHQQANAipwVKVTL 207
Cdd:PRK07364   89 RQIRLSDADYPGVVKFQPTDLgTEALGYVGEHQVLLEALQEFLQSC-PNITWLCPAEVVSV-----EYQQDA---ATVTL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 208 ASGE---SVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPtENNVAWQRFLPSGPIAMLPLSDTESSLV 284
Cdd:PRK07364  160 EIEGkqqTLQSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHEAP-HNDIAYERFWPSGPFAILPLPGNRCQIV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 285 WSTSHQQAQELLELDEESFVDAINSAFWSNENQSELIetagslfrstlsaimpsagSPRQLppsvagigpksrvkFPLGI 364
Cdd:PRK07364  239 WTAPHAQAKALLALPEAEFLAELQQRYGDQLGKLELL-------------------GDRFL--------------FPVQL 285

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 365 GHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMAAIDLM 444
Cdd:PRK07364  286 MQSDRYVQHRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQVLQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLL 365

                         410       420
                  ....*....|....*....|....*....
gi 2008076678 445 KRLYSTNAAPVVLLRTFGLQATNMVPALK 473
Cdd:PRK07364  366 DRLFSNQWWPLVVVRRLGLWLLRHVPPLK 394
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 49-473 1.82e-57

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 193.23  E-value: 1.82e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSLGmdrnLEGKKILLLEAgnkkvmHKVPDTYStRVSSISPGSATLLTGVGAWEHITKmRCKPY 128
Cdd:COG0654     4 TDVLIVGGGPAGLALALALA----RAGIRVTVVER------APPPRPDG-RGIALSPRSLELLRRLGLWDRLLA-RGAPI 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 129 KRMQVWDACSD-VLITFDKEDMQDEMAHIVENDVVVAALTKQLDDLsdNVQVKYRSKVVKYswpmpHQQANAipwVKVTL 207
Cdd:COG0654    72 RGIRVRDGSDGrVLARFDAAETGLPAGLVVPRADLERALLEAARAL--GVELRFGTEVTGL-----EQDADG---VTVTL 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 208 ASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHlseptennVAWQRFLpsgpiamlplsdtesslvwST 287
Cdd:COG0654   142 ADGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVR--------TELRARL-------------------AA 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 288 SHQQAQELLELDeesfvdainsafwsnenqselietagslfrstlsaimpsagsprqlppsvagigpkSRVKFPLGIGHA 367
Cdd:COG0654   195 AGPRLGELLELS--------------------------------------------------------PRSAFPLRRRRA 218

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 368 SEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAmqhLLEYETERQRHNLPMMAAIDLMKRL 447
Cdd:COG0654   219 ERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAALRGRDDEAA---LARYERERRPRAARVQRAADALGRL 295

                         410       420
                  ....*....|....*....|....*.
gi 2008076678 448 YSTNAAPVVLLRTFGLQATNMVPALK 473
Cdd:COG0654   296 FHPDSPPLRLLRNAGLRLLDRLPPLK 321
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 210-433 3.89e-12

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 67.35  E-value: 3.89e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 210 GESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPTENNVA------WQRFLPSGPIAMLPLSDTESS- 282
Cdd:pfam01494 145 EYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDAPDLSDPVErafvhyLIYAPHSRGFMVGPWRSAGREr 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 283 --LVWSTSHQQAQELLELDEESFVDAINSAFwsnenqselietagslfrstlsaimpsagsprQLPPSVAGIGPKSRvkF 360
Cdd:pfam01494 225 yyVQVPWDEEVEERPEEFTDEELKQRLRSIV--------------------------------GIDLALVEILWKSI--W 270

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2008076678 361 PLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSqAAFDGKdlgAMQHLLE-YETERQRH 433
Cdd:pfam01494 271 GVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLA-AVLRGQ---AGESLLDtYSAERLPV 340
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 49-477 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 571.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSLGMDRNLEGKKILLLEAGNKK-----VMHKVPDTYSTRVSSISPGSATLLTGVGAWEHITKM 123
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPklksrNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 124 RCKPYKRMQVWDACSDVLITFDKEDMQDEMAHIVENDVVVAALTKQLDD-LSDNVQVKYRSKVVKYSWPMPHQQANaIPW 202
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNGKEDMACIIENDNIQNSLYNRLQEyNGDNVKILNPARLISVTIPSKYPNDN-SNW 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 203 VKVTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPTENNVAWQRFLPSGPIAMLPLSDTESS 282
Cdd:TIGR01989 160 VHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNST 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 283 LVWSTSHQQAQELLELDEESFVDAINSAF---WSNENQSELIETAGSLFRSTLSAIMPSAGSPRQLPPSVAGIGPKSRVK 359
Cdd:TIGR01989 240 LVWSTSPEEALRLLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 360 FPLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMA 439
Cdd:TIGR01989 320 FPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLG 399

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 2008076678 440 AIDLMKRLYSTNAAPVVLLRTFGLQATNMVPALKEQIM 477
Cdd:TIGR01989 400 LVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 50-481 7.18e-153

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 440.10  E-value: 7.18e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  50 DIIISGGGMVGSAMACSLGMDrnleGKKILLLEAgnKKVMHKVPDTYSTRVSSISPGSATLLTGVGAWEHITKMRCKPYK 129
Cdd:TIGR01988   1 DIVIVGGGMVGLALALALARS----GLKVALIEA--TPLPAPADPGFDNRVSALSAASIRLLEKLGVWDKIEPARAQPIR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 130 RMQVWDACSDVLITFDKEDMQ-DEMAHIVENDVVVAALTKQLDDLSDnvqVKYRSKVVKYSWPmphqqaNAIPWVKVTLA 208
Cdd:TIGR01988  75 DIHVSDGGSFGALRFDADEIGlEALGYVVENRVLQQALWERLQELPN---VTLLCPARVVELP------RHSDHVELTLD 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 209 SGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPTeNNVAWQRFLPSGPIAMLPLSDTESSLVWSTS 288
Cdd:TIGR01988 146 DGQQLRARLLVGADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPH-QGTAWERFTPTGPLALLPLPDNRSSLVWTLP 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 289 HQQAQELLELDEESFVDAINSAFWSnenqselietagslfrstlsaimpsagsprQLPPSVAgigPKSRVKFPLGIGHAS 368
Cdd:TIGR01988 225 PEEAERLLALSDEEFLAELQRAFGS------------------------------RLGAITL---VGERHAFPLSLTHAK 271

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 369 EYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMAAIDLMKRLY 448
Cdd:TIGR01988 272 RYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLRVLQRYERRRRFDNAAMLGATDGLNRLF 351

                         410       420       430
                  ....*....|....*....|....*....|...
gi 2008076678 449 STNAAPVVLLRTFGLQATNMVPALKEQIMGFAS 481
Cdd:TIGR01988 352 SNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAM 384
PRK07364 PRK07364
FAD-dependent hydroxylase;
49-473 9.94e-83

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 261.88  E-value: 9.94e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSLgmdRNlEGKKILLLEAGNKKVMHKVPDTYStrvssISPGSATLLTGVGAWEHItKMRCKPY 128
Cdd:PRK07364   19 YDVAIVGGGIVGLTLAAAL---KD-SGLRIALIEAQPAEAAAAKGQAYA-----LSLLSARIFEGIGVWEKI-LPQIGKF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 129 KRMQVWDACSDVLITFDKEDM-QDEMAHIVENDVVVAALTKQLDDLsDNVQVKYRSKVVKYswpmpHQQANAipwVKVTL 207
Cdd:PRK07364   89 RQIRLSDADYPGVVKFQPTDLgTEALGYVGEHQVLLEALQEFLQSC-PNITWLCPAEVVSV-----EYQQDA---ATVTL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 208 ASGE---SVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPtENNVAWQRFLPSGPIAMLPLSDTESSLV 284
Cdd:PRK07364  160 EIEGkqqTLQSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHEAP-HNDIAYERFWPSGPFAILPLPGNRCQIV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 285 WSTSHQQAQELLELDEESFVDAINSAFWSNENQSELIetagslfrstlsaimpsagSPRQLppsvagigpksrvkFPLGI 364
Cdd:PRK07364  239 WTAPHAQAKALLALPEAEFLAELQQRYGDQLGKLELL-------------------GDRFL--------------FPVQL 285

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 365 GHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMAAIDLM 444
Cdd:PRK07364  286 MQSDRYVQHRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQVLQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLL 365

                         410       420
                  ....*....|....*....|....*....
gi 2008076678 445 KRLYSTNAAPVVLLRTFGLQATNMVPALK 473
Cdd:PRK07364  366 DRLFSNQWWPLVVVRRLGLWLLRHVPPLK 394
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 50-477 1.03e-82

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 261.24  E-value: 1.03e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  50 DIIISGGGMVGSAMACSLGmDRNLegkKILLLEAG-NKKVMHKVPDTystRVSSISPGSATLLTGVGAWEHITKMRCKPY 128
Cdd:PRK08850    6 DVAIIGGGMVGLALAAALK-ESDL---RIAVIEGQlPEEALNELPDV---RVSALSRSSEHILRNLGAWQGIEARRAAPY 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 129 KRMQVWDACSDVLITFDKEDM-QDEMAHIVENDVVVAALTKQLDDLsDNVQVKyrskvvkyswpMPHQQAN-----AIPW 202
Cdd:PRK08850   79 IAMEVWEQDSFARIEFDAESMaQPDLGHIVENRVIQLALLEQVQKQ-DNVTLL-----------MPARCQSiavgeSEAW 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 203 VkvTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPtENNVAWQRFLPSGPIAMLPLSDTE-S 281
Cdd:PRK08850  147 L--TLDNGQALTAKLVVGADGANSWLRRQMDIPLTHWDYGHSALVANVRTVDP-HNSVARQIFTPQGPLAFLPMSEPNmS 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 282 SLVWSTSHQQAQELLELDEESFVDAINSAFwsnENQSELIETAGslfrstlsaimpsagsprqlppsvagigpkSRVKFP 361
Cdd:PRK08850  224 SIVWSTEPLRAEALLAMSDEQFNKALTAEF---DNRLGLCEVVG------------------------------ERQAFP 270

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 362 LGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMAAI 441
Cdd:PRK08850  271 LKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQEILALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAM 350

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 2008076678 442 DLMKRLYSTNAAPVVLLRTFGLQATNMVPALKEQIM 477
Cdd:PRK08850  351 QGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIM 386
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
49-481 2.31e-79

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 252.18  E-value: 2.31e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSLGMdrnlEGKKILLLEAGNKKVmhKVPDTYSTRVSSISPGSATLLTGVGAWEHITKMRCKPY 128
Cdd:PRK07608    6 FDVVVVGGGLVGASLALALAQ----SGLRVALLAPRAPPR--PADDAWDSRVYAISPSSQAFLERLGVWQALDAARLAPV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 129 KRMQVW-DACSDvlITFDKEDM-QDEMAHIVENDVVVAALTKQLDDlSDNVQVkyrskvvkyswpMPHQqANAIPW---- 202
Cdd:PRK07608   80 YDMRVFgDAHAR--LHFSAYQAgVPQLAWIVESSLIERALWAALRF-QPNLTW------------FPAR-AQGLEVdpda 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 203 VKVTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPtENNVAWQRFLPSGPIAMLPLSDTESS 282
Cdd:PRK07608  144 ATLTLADGQVLRADLVVGADGAHSWVRSQAGIKAERRPYRQTGVVANFKAERP-HRGTAYQWFRDDGILALLPLPDGHVS 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 283 LVWSTSHQQAQELLELDEESFVDAINSAfwsnenqselieTAGSLFRstLSAIMPSAGsprqlppsvagigpksrvkFPL 362
Cdd:PRK07608  223 MVWSARTAHADELLALSPEALAARVERA------------SGGRLGR--LECVTPAAG-------------------FPL 269

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 363 GIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAfDGKDLGAMQHLLEYETERQRHNLPMMAAID 442
Cdd:PRK07608  270 RLQRVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLAGRE-PFRDLGDLRLLRRYERARREDILALQVATD 348

                         410       420       430
                  ....*....|....*....|....*....|....*....
gi 2008076678 443 LMKRLYSTNAAPVVLLRTFGLQATNMVPALKEQIMGFAS 481
Cdd:PRK07608  349 GLQRLFALPGPLARWLRNAGMALVGALPLVKRWLVRHAL 387
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 50-473 1.60e-78

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 250.52  E-value: 1.60e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  50 DIIISGGGMVGSAMACSLgmdrNLEGKKILLLEAGNKKVMHKVPDT-YSTRVSSISPGSATLLTGVGAWEHITKMRCKPY 128
Cdd:PRK05714    4 DLLIVGAGMVGSALALAL----QGSGLEVLLLDGGPLSVKPFDPQApFEPRVSALSAASQRILERLGAWDGIAARRASPY 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 129 KRMQVWDACSDVLITFDKEDMQDE-MAHIVENDVVVAALTKQLDDLSDNVQVKYRSKVVKYSwpmphqqanAIPWVkVTL 207
Cdd:PRK05714   80 SEMQVWDGSGTGQIHFSAASVHAEvLGHIVENRVVQDALLERLHDSDIGLLANARLEQMRRS---------GDDWL-LTL 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 208 ASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPtENNVAWQRFLPSGPIAMLPLSDTES----SL 283
Cdd:PRK05714  150 ADGRQLRAPLVVAADGANSAVRRLAGCATREWDYLHHAIVTSVRCSEP-HRATAWQRFTDDGPLAFLPLERDGDehwcSI 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 284 VWSTSHQQAQELLELDEESFVDAINSAFwsnenqselietAGSLfrstlsaimpsaGSPRQLPPsvagigpksRVKFPLG 363
Cdd:PRK05714  229 VWSTTPEEAERLMALDDDAFCAALERAF------------EGRL------------GEVLSADP---------RLCVPLR 275

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 364 IGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMAAIDL 443
Cdd:PRK05714  276 QRHAKRYVEPGLALIGDAAHTIHPLAGQGVNLGFLDAAVLAEVLLHAAERGERLADVRVLSRFERRRMPHNLALMAAMEG 355

                         410       420       430
                  ....*....|....*....|....*....|
gi 2008076678 444 MKRLYSTNAAPVVLLRTFGLQATNMVPALK 473
Cdd:PRK05714  356 FERLFQADPLPLRWLRNTGLKLVDQMPEAK 385
PRK08013 PRK08013
oxidoreductase; Provisional
 49-478 5.46e-78

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 249.19  E-value: 5.46e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSL-GmdrnlEGKKILLLEagNKKVMHKVPD-TYSTRVSSISPGSATLLTGVGAWEHITKMRCK 126
Cdd:PRK08013    4 VDVVIAGGGMVGLAVACGLqG-----SGLRVAVLE--QRVPEPLAADaPPALRVSAINAASEKLLTRLGVWQDILARRAS 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 127 PYKRMQVWDACSDVLITFDKEDMQ-DEMAHIVENDVVVAALTKQLDDLSDnvqvkyrskvVKYSWPMPHQQanaIPW--- 202
Cdd:PRK08013   77 CYHGMEVWDKDSFGRIAFDDQSMGySHLGHIIENSVIHYALWQKAQQSSD----------ITLLAPAELQQ---VAWgen 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 203 -VKVTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPtENNVAWQRFLPSGPIAMLPLSDTE- 280
Cdd:PRK08013  144 eAFLTLKDGSMLTARLVVGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEP-HDAVARQVFHGDGILAFLPLSDPHl 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 281 SSLVWSTSHQQAQELLELDEESFVDAINSAFWSNENQSELIetagslfrstlsaimpsagSPRQLppsvagigpksrvkF 360
Cdd:PRK08013  223 CSIVWSLSPEEAQRMQQAPEEEFNRALAIAFDNRLGLCELE-------------------SERQV--------------F 269

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 361 PLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMAA 440
Cdd:PRK08013  270 PLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELRRLHRQGKDIGQHLYLRRYERSRKHSAALMLAG 349

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 2008076678 441 IDLMKRLYSTNAAPVVLLRTFGLQATNMVPALK----EQIMG 478
Cdd:PRK08013  350 MQGFRDLFAGNNPAKKLLRDIGLKLADTLPGVKpqliRQAMG 391
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 46-480 3.21e-77

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 246.82  E-value: 3.21e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  46 NEVYDIIISGGGMVGSAMACSLGMdrnlEGKKILLLE--AGNKKVMHKVPDTystRVSSISPGSATLLTGVGAWEHITKM 123
Cdd:PRK08020    3 NQPTDIAIVGGGMVGAALALGLAQ----HGFSVAVLEhaAPAPFDADSQPDV---RISAISAASVALLKGLGVWDAVQAM 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 124 RCKPYKRMQVWDAcSDVLITFDKEDMQ-DEMAHIVENDVVVAALTKQLDDlSDNVQVKYRSKVVKYSWPMPHQQanaipw 202
Cdd:PRK08020   76 RSHPYRRLETWEW-ETAHVVFDAAELKlPELGYMVENRVLQLALWQALEA-HPNVTLRCPASLQALQRDDDGWE------ 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 203 vkVTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPTENnVAWQRFLPSGPIAMLPLSDTESS 282
Cdd:PRK08020  148 --LTLADGEEIQAKLVIGADGANSQVRQMAGIGVHGWQYRQSCMLISVKCENPPGD-STWQQFTPSGPRAFLPLFDNWAS 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 283 LVWSTSHQ-----QAQELLELDEEsfvdainsafwsnenqselIETAgslFRSTLSAIMP-SAGSprqlppsvagigpks 356
Cdd:PRK08020  225 LVWYDSPArirqlQAMSMAQLQQE-------------------IAAH---FPARLGAVTPvAAGA--------------- 267

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 357 rvkFPLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLP 436
Cdd:PRK08020  268 ---FPLTRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVLVNARSYGEAWASEAVLKRYQRRRMADNLL 344

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....
gi 2008076678 437 MMAAIDLMKRLYSTNAAPVVLLRTFGLQATNMVPALKEQIMGFA 480
Cdd:PRK08020  345 MQSGMDLFYAGFSNNLPPLRFARNLGLMAAQRAGVLKRQALKYA 388
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 50-478 3.40e-75

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 241.06  E-value: 3.40e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  50 DIIISGGGMVGSAMACSLGMDRNLegkKILLLEAgnkKVMHKVPDTYSTRVSSISPGSATLLTGVGAWEHITKMRCkPYK 129
Cdd:TIGR01984   1 DVIIVGGGLVGLSLALALSRLGKI---KIALIEA---NSPSAAQPGFDARSLALSYGSKQILEKLGLWPKLAPFAT-PIL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 130 RMQVWDACSDVLITFDKEDMQDE-MAHIVENDVVVAALTKQLDDLSdNVQvkyrskvvkysWPMPHQQANAIP---WVKV 205
Cdd:TIGR01984  74 DIHVSDQGHFGATHLRASEFGLPaLGYVVELADLGQALLSRLALLT-NIQ-----------LYCPARYKEIIRnqdYVRV 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 206 TLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPTENnVAWQRFLPSGPIAMLPLSDTE-SSLV 284
Cdd:TIGR01984 142 TLDNGQQLRAKLLIAADGANSKVRELLSIPTEEHDYNQTALIANIRHEQPHQG-CAFERFTPHGPLALLPLKDNYrSSLV 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 285 WSTSHQQAQELLELDEESFVDAINSAFwsnenqselietaGslfrstlsaimPSAGSPRQlppsvagIGPKSRvkFPLGI 364
Cdd:TIGR01984 221 WCLPSKQADTIANLPDAEFLAELQQAF-------------G-----------WRLGKITQ-------VGERKT--YPLKL 267

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 365 GHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAfdgKDLGAMQHLLEYETERQRHNLPMMAAIDLM 444
Cdd:TIGR01984 268 RIAETHVHPRVVLIGNAAQTLHPIAGQGFNLGLRDVETLAEVLIDAR---IDLGTYALLQEYLRRRQFDQFITIGLTDGL 344

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 2008076678 445 KRLYSTNAAPVVLLRTFGLQATNMVPALKE----QIMG 478
Cdd:TIGR01984 345 NRLFSNHIPLLRALRNLGLLALENFPPLKKrlarQAMG 382
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
49-481 1.52e-73

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 237.57  E-value: 1.52e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSLGMDRNleGKKILLLEAGNKKVMHKVPdtystRVSSISPGSATLLTGVGAWEHItKMRCKPY 128
Cdd:PRK07333    2 CDVVIAGGGYVGLALAVALKQAAP--HLPVTVVDAAPAGAWSRDP-----RASAIAAAARRMLEALGVWDEI-APEAQPI 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 129 KRMQVWDA-CSD----VLITFDKEDMQDE-MAHIVENDVVVAALTKQLDDLsdNVQVKYRSKVVKYswpmpHQQANAipw 202
Cdd:PRK07333   74 TDMVITDSrTSDpvrpVFLTFEGEVEPGEpFAHMVENRVLINALRKRAEAL--GIDLREATSVTDF-----ETRDEG--- 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 203 VKVTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSA-VVAVLHlsEPTENNVAWQRFLPSGPIAMLPLSDTES 281
Cdd:PRK07333  144 VTVTLSDGSVLEARLLVAADGARSKLRELAGIKTVGWDYGQSGiVCTVEH--ERPHGGRAEEHFLPAGPFAILPLKGNRS 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 282 SLVWSTSHQQAQELLELDEESFvdainsafwsnenQSELiETAgslFRSTLSAIMPsAGSPRqlppsvagigpksrvKFP 361
Cdd:PRK07333  222 SLVWTERTADAERLVALDDLVF-------------EAEL-EQR---FGHRLGELKV-LGKRR---------------AFP 268

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 362 LGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMAAI 441
Cdd:PRK07333  269 LGLTLARSFVAPRFALVGDAAHGIHPIAGQGLNLGLKDVAALAEVVVEAARLGLDIGSLDVLERYQRWRRFDTVRMGVTT 348

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 2008076678 442 DLMKRLYSTNAAPVVLLRTFGLQATNMVPALKEQIMGFAS 481
Cdd:PRK07333  349 DVLNRLFSNDSTLLRSVRDIGLGLVDRLPKLKSFFIRQAA 388
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 49-480 4.02e-68

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 222.72  E-value: 4.02e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMAcsLGMDRnlEGKKILLLEAGNKKVMHKVPDTySTRVSSISPGSATLLTGVGAWEHITKMRCKPY 128
Cdd:PRK08849    4 YDIAVVGGGMVGAATA--LGFAK--QGRSVAVIEGGEPKAFEPSQPM-DIRVSAISQTSVDLLESLGAWSSIVAMRVCPY 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 129 KRMQVWDAcSDVLITFDKEDMQ-DEMAHIVENDVVVAALTKQLdDLSDNVQVKYRSKVVKYSWpmpHQQANaipwvKVTL 207
Cdd:PRK08849   79 KRLETWEH-PECRTRFHSDELNlDQLGYIVENRLIQLGLWQQF-AQYPNLTLMCPEKLADLEF---SAEGN-----RVTL 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 208 ASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPtENNVAWQRFLPSGPIAMLPLSDTESSLVWST 287
Cdd:PRK08849  149 ESGAEIEAKWVIGADGANSQVRQLAGIGITAWDYRQHCMLINVETEQP-QQDITWQQFTPSGPRSFLPLCGNQGSLVWYD 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 288 SHQQAQELLELDEESFvdainsafwsnenQSELIetagslfrstlsaimpsagspRQLPPSVAGIGPKSRVKFPLGIGHA 367
Cdd:PRK08849  228 SPKRIKQLSAMNPEQL-------------RSEIL---------------------RHFPAELGEIKVLQHGSFPLTRRHA 273

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 368 SEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMqhlleYETERQRHNLPMMAAIDLMKRL 447
Cdd:PRK08849  274 QQYVKNNCVLLGDAAHTINPLAGQGVNLGFKDVDVLLAETEKQGVLNDASFAR-----YERRRRPDNLLMQTGMDLFYKT 348

                         410       420       430
                  ....*....|....*....|....*....|...
gi 2008076678 448 YSTNAAPVVLLRTFGLQATNMVPALKEQIMGFA 480
Cdd:PRK08849  349 FSNSLTPLKFVRNAALKLAENSGPLKTQVLKYA 381
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
50-472 4.80e-66

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 217.81  E-value: 4.80e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  50 DIIISGGGMVGSAMACSLgmdrNLEGKKILLLEAGNKKVMHkvPDTYSTRVSSISPGSATLLTGVGAWEHITKMRCKPYK 129
Cdd:PRK08773    8 DAVIVGGGVVGAACALAL----ADAGLSVALVEGREPPRWQ--ADQPDLRVYAFAADNAALLDRLGVWPAVRAARAQPYR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 130 RMQVWDACSDVLITFDKEDM-QDEMAHIVENDVVVAALTKQLDdlSDNVQVKYRSKVVKYswpmpHQQANAipwVKVTLA 208
Cdd:PRK08773   82 RMRVWDAGGGGELGFDADTLgREQLGWIVENDLLVDRLWAALH--AAGVQLHCPARVVAL-----EQDADR---VRLRLD 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 209 SGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPTENNvAWQRFLPSGPIAMLPLSDTESSLVWSTS 288
Cdd:PRK08773  152 DGRRLEAALAIAADGAASTLRELAGLPVSRHDYAQRGVVAFVDTEHPHQAT-AWQRFLPTGPLALLPFADGRSSIVWTLP 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 289 HQQAQELLELDEESFVDAINSAFwsnenqselietAGSLfrstlsaimpsaGSPRQLPPsvagigpksRVKFPLGIGHAS 368
Cdd:PRK08773  231 DAEAERVLALDEAAFSRELTQAF------------AARL------------GEVRVASP---------RTAFPLRRQLVQ 277

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 369 EYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMAAIDLMKRLY 448
Cdd:PRK08773  278 QYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAHARRADWAAPHRLQRWARTRRSDNTVAAYGFDAINRVF 357

                         410       420
                  ....*....|....*....|....
gi 2008076678 449 STNAAPVVLLRTFGLQATNMVPAL 472
Cdd:PRK08773  358 SNDEMHLTLLRGSVLGLAGKLPPL 381
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 49-479 9.45e-65

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 214.33  E-value: 9.45e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSLgmDRNLEGK-KILLLEAgnKKVMHKVPDTYSTRVSSISPGSATLLTGVGAWEHItKMRCKP 127
Cdd:PRK05732    4 MDVIIVGGGMAGATLALAL--SRLSHGGlPVALIEA--FAPESDAHPGFDARAIALAAGTCQQLARLGVWQAL-ADCATP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 128 YKRMQVWDACSDVLITFDKEDMQ-DEMAHIVENDVVVAALTKQLDDlSDNVQVKYRSKVVKyswpMPHQQANaipwVKVT 206
Cdd:PRK05732   79 ITHIHVSDRGHAGFVRLDAEDYGvPALGYVVELHDVGQRLFALLDK-APGVTLHCPARVAN----VERTQGS----VRVT 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 207 LASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPtENNVAWQRFLPSGPIAMLPLSDTESSLVWS 286
Cdd:PRK05732  150 LDDGETLTGRLLVAADGSHSALREALGIDWQQHPYEQVAVIANVTTSEA-HQGRAFERFTEHGPLALLPMSDGRCSLVWC 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 287 TSHQQAQELLELDEESFVDAINSAF-WsnenqselietagslfRstlsaimpsAGSPRQlppsvagIGPksRVKFPLGIG 365
Cdd:PRK05732  229 HPLEDAEEVLSWSDAQFLAELQQAFgW----------------R---------LGRITH-------AGK--RSAYPLALV 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 366 HASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQ--RHNLPMMAaiDL 443
Cdd:PRK05732  275 TAAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQALARGEDIGDYAVLQRYQQRRQqdREATIGFT--DG 352

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 2008076678 444 MKRLYSTNAAPVVLLRTFGLQATNMVPALK----EQIMGF 479
Cdd:PRK05732  353 LVRLFANRWAPLVVGRNLGLMAMDLLPPARdwlaRRTLGW 392
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 49-473 1.82e-57

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 193.23  E-value: 1.82e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSLGmdrnLEGKKILLLEAgnkkvmHKVPDTYStRVSSISPGSATLLTGVGAWEHITKmRCKPY 128
Cdd:COG0654     4 TDVLIVGGGPAGLALALALA----RAGIRVTVVER------APPPRPDG-RGIALSPRSLELLRRLGLWDRLLA-RGAPI 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 129 KRMQVWDACSD-VLITFDKEDMQDEMAHIVENDVVVAALTKQLDDLsdNVQVKYRSKVVKYswpmpHQQANAipwVKVTL 207
Cdd:COG0654    72 RGIRVRDGSDGrVLARFDAAETGLPAGLVVPRADLERALLEAARAL--GVELRFGTEVTGL-----EQDADG---VTVTL 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 208 ASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHlseptennVAWQRFLpsgpiamlplsdtesslvwST 287
Cdd:COG0654   142 ADGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVR--------TELRARL-------------------AA 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 288 SHQQAQELLELDeesfvdainsafwsnenqselietagslfrstlsaimpsagsprqlppsvagigpkSRVKFPLGIGHA 367
Cdd:COG0654   195 AGPRLGELLELS--------------------------------------------------------PRSAFPLRRRRA 218

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 368 SEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAmqhLLEYETERQRHNLPMMAAIDLMKRL 447
Cdd:COG0654   219 ERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAALRGRDDEAA---LARYERERRPRAARVQRAADALGRL 295

                         410       420
                  ....*....|....*....|....*.
gi 2008076678 448 YSTNAAPVVLLRTFGLQATNMVPALK 473
Cdd:COG0654   296 FHPDSPPLRLLRNAGLRLLDRLPPLK 321
PRK09126 PRK09126
FAD-dependent hydroxylase;
49-479 6.79e-49

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 172.43  E-value: 6.79e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  49 YDIIISGGGMVGSAMACSLGMDrnleGKKILLLEAGNKKVMHKVPdtYSTRVSSISPGSATLLTGVGAWEHITKMRCKPY 128
Cdd:PRK09126    4 SDIVVVGAGPAGLSFARSLAGS----GLKVTLIERQPLAALADPA--FDGREIALTHASREILQRLGAWDRIPEDEISPL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 129 KRMQVWDACSDVLITFD-KEDMQDEMAHIVENDVVVAALTKQLDDlSDNVQVKYRSKVVKYswpmpHQQANaipWVKVTL 207
Cdd:PRK09126   78 RDAKVLNGRSPFALTFDaRGRGADALGYLVPNHLIRRAAYEAVSQ-QDGIELLTGTRVTAV-----RTDDD---GAQVTL 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 208 ASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPtENNVAWQRFLPSGPIAMLPLSDTESSLVWST 287
Cdd:PRK09126  149 ANGRRLTARLLVAADSRFSATRRQLGIGADMHDFGRTMLVCRMRHELP-HHHTAWEWFGYGQTLALLPLNGHLSSLVLTL 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 288 SHQQAQELLELDEESFvdainsafwsNENQSElietagsLFRSTLSAIMPSAgsprqlppsvagigpkSRVKFPLGIGHA 367
Cdd:PRK09126  228 PPDQIEALLALDPEAF----------AAEVTA-------RFKGRLGAMRLVS----------------SRHAYPLVAVYA 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 368 SEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQHLLEYETERQRHNLPMMAAIDLMKRL 447
Cdd:PRK09126  275 HRFVAKRFALIGDAAVGMHPVTAHGFNLGLKGQDILARLILAAARRGQDIGAASLLERYERKHRLATRPLYHATNAIAAL 354

                         410       420       430
                  ....*....|....*....|....*....|..
gi 2008076678 448 YSTNAAPVVLLRTFGLQATNMVPALKEQIMGF 479
Cdd:PRK09126  355 YTDDRPPARLLRRAVLRAANRFPPLKQAIAKQ 386
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
45-477 8.13e-43

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 155.83  E-value: 8.13e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  45 KNEVYDIIISGGGMVGSAMACSLGMdrnlEGKKILLLEAgnkkvmhkVPDTYSTRVSSISPGSATLLTGVGAWEhitkmR 124
Cdd:PRK07494    4 EKEHTDIAVIGGGPAGLAAAIALAR----AGASVALVAP--------EPPYADLRTTALLGPSIRFLERLGLWA-----R 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 125 CKPY----KRMQVWDACSDVL----ITFDKEDMQDE-MAHIVENDVVVAALTKQLDDLSdNVQvkyRSKVVKYSWpmpHQ 195
Cdd:PRK07494   67 LAPHaaplQSMRIVDATGRLIrapeVRFRAAEIGEDaFGYNIPNWLLNRALEARVAELP-NIT---RFGDEAESV---RP 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 196 QANAipwVKVTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVV-AVLHlSEPTEnNVAWQRFLPSGPIAML 274
Cdd:PRK07494  140 REDE---VTVTLADGTTLSARLVVGADGRNSPVREAAGIGVRTWSYPQKALVlNFTH-SRPHQ-NVSTEFHTEGGPFTQV 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 275 PLSDTESSLVWSTSHQQAQELLELDEESFVDAInsafwsnENQSELIetagsLFRSTLsaimpsaGSPRQLppsvagigp 354
Cdd:PRK07494  215 PLPGRRSSLVWVVRPAEAERLLALSDAALSAAI-------EERMQSM-----LGKLTL-------EPGRQA--------- 266

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 355 ksrvkFPLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQaafDGKDLGAMQHLLEYETERQRHN 434
Cdd:PRK07494  267 -----WPLSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLGLRDVATLVEIVED---RPEDPGSAAVLAAYDRARRPDI 338

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 2008076678 435 LPMMAAIDLMKRLYSTNAAPVVLLRTFGLQATNMVPALKEQIM 477
Cdd:PRK07494  339 LSRTASVDLLNRSLLSDFLPVQDLRAAGLHLLYSFGPLRRLFM 381
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
48-476 1.15e-38

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 144.83  E-value: 1.15e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  48 VYDIIISGGGMVGSAMACSLGMDRNLEGKKILLLEAGNKKVMHKVPdtystRVSSISPGSATLLTGVGAW-------EHI 120
Cdd:PRK06996   11 DFDIAIVGAGPVGLALAGWLARRSATRALSIALIDAREPAASANDP-----RAIALSHGSRVLLETLGAWpadatpiEHI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 121 TKMRCKPYKRmqvwdacsdVLITFDKEDMQdEMAHIVENDVVVAALTKQLDDLSDNVQVKYRSKVvkyswpmPHQQANAI 200
Cdd:PRK06996   86 HVSQRGHFGR---------TLIDRDDHDVP-ALGYVVRYGSLVAALARAVRGTPVRWLTSTTAHA-------PAQDADGV 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 201 PWVKVTLASGESVETKLLIGADGP-NSMVRQELGIPTVKWNYDQSAVVAVLHLSEPTENnVAWQRFLPSGPIAMLPLSDT 279
Cdd:PRK06996  149 TLALGTPQGARTLRARIAVQAEGGlFHDQKADAGDSARRRDYGQTAIVGTVTVSAPRPG-WAWERFTHEGPLALLPLGGP 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 280 ---ESSLVWSTSHQQAQELLELDEESFVDAINSAFWSNenqselietagsLFRSTLsaimpsagsprqlppsvagIGPks 356
Cdd:PRK06996  228 rqaDYALVWCCAPDEAARRAALPDDAFLAELGAAFGTR------------MGRFTR-------------------IAG-- 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 357 RVKFPLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAMQhlleyeterQRHNLP 436
Cdd:PRK06996  275 RHAFPLGLNAARTLVNGRIAAVGNAAQTLHPVAGQGLNLGLRDAHTLADALSDHGATPLALATFA---------ARRALD 345

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 2008076678 437 ---MMAAIDLMKRLYSTNAAPVVLLRTFGLQATNMVPALKEQI 476
Cdd:PRK06996  346 rrvTIGATDLLPRLFTVDSRPLAHLRGAALTALEFVPPLKHAL 388
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 50-480 2.96e-31

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 123.88  E-value: 2.96e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  50 DIIISGGGMVGSAMACSLGMdrnlEGKKILLLEAgnKKVmhKVPDTYS-TRVSSISPGSATLLTGVGAWEHITKMRCKPY 128
Cdd:PRK06617    3 NTVILGCGLSGMLTALSFAQ----KGIKTTIFES--KSV--KSPEFFKdIRTTALTPHSKNFLFSIDIWEELEKFVAEMQ 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 129 KRMQVWDACSDVLITfdKEDMQDEMAHIVEND----VVVAALTKQ-LDDLSDNVQvkyrskvvkYSWPMPHQQANAIPWv 203
Cdd:PRK06617   75 DIYVVDNKASEILDL--RNDADAVLGYVVKNSdfkkILLSKITNNpLITLIDNNQ---------YQEVISHNDYSIIKF- 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 204 kvtlaSGESVETKLLIGADGPNSMVRQELGIPTVKWNYdQSAVVAVLHLSEPTENnVAWQRFLPSGPIAMLPLSDT-ESS 282
Cdd:PRK06617  143 -----DDKQIKCNLLIICDGANSKVRSHYFANEIEKPY-QTALTFNIKHEKPHEN-CAMEHFLPLGPFALLPLKDQyASS 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 283 LVWSTSHQQAQELLELDEESFvdainsAFWSNENqselieTAGSLFRSTLSAIMPSagsprqlppsvagigpksrvkFPL 362
Cdd:PRK06617  216 VIWSTSSDQAALIVNLPVEEV------RFLTQRN------AGNSLGKITIDSEISS---------------------FPL 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 363 GIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAafdgkdlGAMQhllEYETERQRHNLPMMAAID 442
Cdd:PRK06617  263 KARIANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDIEILSMIVSNN-------GTLQ---EYQKLRQEDNFIMYKLTD 332

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 2008076678 443 LMKRLYSTNAAPVVLLRTFGLQATNMVPALKEQIMGFA 480
Cdd:PRK06617  333 ELNNIFSNYSKNLRCLRQIGFKVINNFKPIKNLITSYA 370
PRK07045 PRK07045
putative monooxygenase; Reviewed
 204-472 1.86e-12

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 68.78  E-value: 1.86e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 204 KVTLASGESVETKLLIGADGPNSMVRQE-LGIPTVKWNYDQSAVVAVLHLSEPT-ENNvawQRFLPS--GPIAMLPLSDT 279
Cdd:PRK07045  143 SVTLSDGERVAPTVLVGADGARSMIRDDvLRMPAERVPYATPMAFGTIALTDSVrECN---RLYVDSnqGLAYFYPIGDQ 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 280 ESSLVWStshqqaqelleldeesfvdainsaFWSNENQSELIETAGSLFRSTLSAIMPSAGSPrqlppSVAGIGPKSRVK 359
Cdd:PRK07045  220 ATRLVVS------------------------FPADEMQGYLADTTRTKLLARLNEFVGDESAD-----AMAAIGAGTAFP 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 360 -FPLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAfdgKDLGAMQHLLE-YETERQRHNLPM 437
Cdd:PRK07045  271 lIPLGRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAGELGACLDLHL---SGQIALADALErFERIRRPVNEAV 347

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2008076678 438 MAAIDLMKRLYSTNAAPVVLLRTfGLQATNMVPAL 472
Cdd:PRK07045  348 ISYGHALATTYHDRAALVANFRS-QLQTSGRDAAW 381
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 210-433 3.89e-12

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 67.35  E-value: 3.89e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 210 GESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPTENNVA------WQRFLPSGPIAMLPLSDTESS- 282
Cdd:pfam01494 145 EYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDAPDLSDPVErafvhyLIYAPHSRGFMVGPWRSAGREr 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 283 --LVWSTSHQQAQELLELDEESFVDAINSAFwsnenqselietagslfrstlsaimpsagsprQLPPSVAGIGPKSRvkF 360
Cdd:pfam01494 225 yyVQVPWDEEVEERPEEFTDEELKQRLRSIV--------------------------------GIDLALVEILWKSI--W 270

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2008076678 361 PLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSqAAFDGKdlgAMQHLLE-YETERQRH 433
Cdd:pfam01494 271 GVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLA-AVLRGQ---AGESLLDtYSAERLPV 340
PRK06126 PRK06126
hypothetical protein; Provisional
 174-431 1.68e-09

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 60.01  E-value: 1.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 174 SDNVQVKYRSKVVKYSwpmphQQANAIPWVKVTLASGES--VETKLLIGADGPNSMVRQELGIP---TVKWNYDQSAVVA 248
Cdd:PRK06126  139 QPGVTLRYGHRLTDFE-----QDADGVTATVEDLDGGESltIRADYLVGCDGARSAVRRSLGISyegTSGLQRDLSIYIR 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 249 VLHLSEPTENNVAWQRFL----PSGPIAMLPLSDTesslvWSTSHQQAQEllelDEESFVDAinsafwsnenqselieTA 324
Cdd:PRK06126  214 APGLAALVGHDPAWMYWLfnpdRRGVLVAIDGRDE-----WLFHQLRGGE----DEFTIDDV----------------DA 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 325 GSLFRSTLsaimpsaGSPrqLPPSVAGIGPksrvkfplGIGH---ASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVA 401
Cdd:PRK06126  269 RAFVRRGV-------GED--IDYEVLSVVP--------WTGRrlvADSYRRGRVFLAGDAAHLFTPTGGYGMNTGIGDAV 331

                         250       260       270
                  ....*....|....*....|....*....|
gi 2008076678 402 CLTRILsQAAFDGkdLGAMQHLLEYETERQ 431
Cdd:PRK06126  332 NLAWKL-AAVLNG--WAGPALLDSYEAERR 358
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 46-409 1.64e-07

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 53.70  E-value: 1.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  46 NEVYDIIISGGGMVGSAMACSLGMdrnlEGKKILLLEagnkKVMHKVPDtystRVSS--ISPGSATLLTGVGAWEHITK- 122
Cdd:PTZ00367   31 NYDYDVIIVGGSIAGPVLAKALSK----QGRKVLMLE----RDLFSKPD----RIVGelLQPGGVNALKELGMEECAEGi 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 123 -MRCK--------------PYK-----------------RMQVWDACSDvlitfdkedmqdeMAHIVENdVVVAALTKQL 170
Cdd:PTZ00367   99 gMPCFgyvvfdhkgkqvklPYGagasgvsfhfgdfvqnlRSHVFHNCQD-------------NVTMLEG-TVNSLLEEGP 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 171 DDLSDNVQVKYrSKVVKYSWPMPHQQANAIPWVKVTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVL 250
Cdd:PTZ00367  165 GFSERAYGVEY-TEAEKYDVPENPFREDPPSANPSATTVRKVATAPLVVMCDGGMSKFKSRYQHYTPASENHSHFVGLVL 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 251 ---HLSEPTENNVAwqrFLPSGPIAMLPLSDTESSLV-------WSTSHQQAQELLE-----LDE---ESFVDAINSAfw 312
Cdd:PTZ00367  244 knvRLPKEQHGTVF---LGKTGPILSYRLDDNELRVLvdynkptLPSLEEQSEWLIEdvaphLPEnmrESFIRASKDT-- 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 313 snenqselietagSLFRSTLSAIMPSAgsprqlPPSVAGigpksrvkfplgighaseyirhrVALIGDAAHRVHPLAGQG 392
Cdd:PTZ00367  319 -------------KRIRSMPNARYPPA------FPSIKG-----------------------YVGIGDHANQRHPLTGGG 356

                         410
                  ....*....|....*..
gi 2008076678 393 ANLGFGDVACLTRILSQ 409
Cdd:PTZ00367  357 MTCCFSDCIRLAKSLTG 373
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
374-447 7.78e-07

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 51.45  E-value: 7.78e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2008076678 374 RVALIGDAAHRVHPLAGQGANLGFGDVACLT----RILSQAAFDGkdlgamqhLLE-YETERQRHnlpMMAAIDLMKRL 447
Cdd:PRK06183  287 RVLLAGDAAHLMPPFAGQGMNSGIRDAANLAwklaAVLRGRAGDA--------LLDtYEQERRPH---ARAMIDLAVRL 354
PRK06184 PRK06184
hypothetical protein; Provisional
 205-440 1.10e-06

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 51.14  E-value: 1.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 205 VTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQS-AVVAVLHLS--EPTennvAWQRFLPS--GPIAMLPLSDT 279
Cdd:PRK06184  147 AGPAGEETVRARYLVGADGGRSFVRKALGIGFPGETLGIDrMLVADVSLTglDRD----AWHQWPDGdmGMIALCPLPGT 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 280 ESSlvwstshqQAQELLELDEEsfvdainsafwsnenqselIETAGSLFRSTLSAImpSAGSPRQL--PPSVAGIGPKSR 357
Cdd:PRK06184  223 DLF--------QIQAPLPPGGE-------------------PDLSADGLTALLAER--TGRTDIRLhsVTWASAFRMNAR 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 358 VkfplgighASEYIRHRVALIGDAAHrVHPLAG-QGANLGFGDVACLTRILSQAAfdgkdLGAMQHLLE-YETERqrhnL 435
Cdd:PRK06184  274 L--------ADRYRVGRVFLAGDAAH-VHPPAGgQGLNTSVQDAYNLGWKLAAVL-----AGAPEALLDtYEEER----R 335


                  ....*
gi 2008076678 436 PMMAA 440
Cdd:PRK06184  336 PVAAA 340
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
56-249 8.39e-06

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 47.27  E-value: 8.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678  56 GGMVGSAMACSLGMdrnlEGKKILLLEAGNKKVMHKVPDtystrvsSISPGSATLLTGVGAWEHITKmrckPYKRMQVWd 135
Cdd:COG0644     1 AGPAGSAAARRLAR----AGLSVLLLEKGSFPGDKICGG-------GLLPRALEELEPLGLDEPLER----PVRGARFY- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 136 ACSDVLITFDKEDmqdEMAHIVENDVVVAALTKQLDDLsdNVQVKYRSKVVKyswpmPHQQANAipwVKVTLASGESVET 215
Cdd:COG0644    65 SPGGKSVELPPGR---GGGYVVDRARFDRWLAEQAEEA--GAEVRTGTRVTD-----VLRDDGR---VVVRTGDGEEIRA 131

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2008076678 216 KLLIGADGPNSMVRQELGIPTvKWNYDQSAVVAV 249
Cdd:COG0644   132 DYVVDADGARSLLARKLGLKR-RSDEPQDYALAI 164
PRK06753 PRK06753
hypothetical protein; Provisional
 203-433 1.23e-05

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 47.38  E-value: 1.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 203 VKVTLASGESVETKLLIGADGPNSMVRQELGiPTVKWNYDQ----SAVVAVLHLSEPtenNVAWQRFLPSGPIAMLPLSD 278
Cdd:PRK06753  129 VTIHFADGESEAFDLCIGADGIHSKVRQSVN-ADSKVRYQGytcfRGLIDDIDLKLP---DCAKEYWGTKGRFGIVPLLN 204

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 279 TEssLVW----------------STSHQQAQElleldeESFVDAINSAFwsnENQSELietagSLFRSTLSAIMPsagsp 342
Cdd:PRK06753  205 NQ--AYWfitinakerdpkyssfGKPHLQAYF------NHYPNEVREIL---DKQSET-----GILHHDIYDLKP----- 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 343 rqlppsvagigpksrvkfplgighASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDgkdlgamQH 422
Cdd:PRK06753  264 ------------------------LKSFVYGRIVLLGDAAHATTPNMGQGAGQAMEDAIVLANCLNAYDFE-------KA 312

                         250
                  ....*....|.
gi 2008076678 423 LLEYETERQRH 433
Cdd:PRK06753  313 LQRYDKIRVKH 323
PRK06834 PRK06834
hypothetical protein; Provisional
 203-399 4.99e-05

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 45.78  E-value: 4.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 203 VKVTLASGESVETKLLIGADGPNSMVRQELGIPTVKWNYDQSAVVAVLHLSEPTENNV--------AWQRFLPSGPIAML 274
Cdd:PRK06834  133 VDVELSDGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEEPEWGVhrdalgihAFGRLEDEGPVRVM 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 275 PlsdTESSLVWSTShqqaQELLELDEEsfvdainsafwsnenqseLIETAGSLFrstlsaimpsagsprqlppsvaGI-G 353
Cdd:PRK06834  213 V---TEKQVGATGE----PTLDDLREA------------------LIAVYGTDY----------------------GIhS 245

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2008076678 354 PKSRVKFPLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGD 399
Cdd:PRK06834  246 PTWISRFTDMARQAASYRDGRVLLAGDAAHVHSPVGGQGLNTGVQD 291
PRK07538 PRK07538
hypothetical protein; Provisional
 374-447 3.09e-04

hypothetical protein; Provisional


Pssm-ID: 236046 [Multi-domain]  Cd Length: 413  Bit Score: 42.96  E-value: 3.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 374 RVALIGDAAHRVHPLAGQGAnlgfgdvacltrilSQAAFDGKDLGAM--------QHLLEYETERqrhnLPMMAAIDLMK 445
Cdd:PRK07538  298 RVTLLGDAAHPMYPVGSNGA--------------SQAILDARALADAlaahgdpeAALAAYEAER----RPATAQIVLAN 359


                  ..
gi 2008076678 446 RL 447
Cdd:PRK07538  360 RL 361
PRK07190 PRK07190
FAD-binding protein;
206-235 1.85e-03

FAD-binding protein;


Pssm-ID: 235955 [Multi-domain]  Cd Length: 487  Bit Score: 40.57  E-value: 1.85e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 2008076678 206 TLASGESVETKLLIGADGPNSMVRQELGIP 235
Cdd:PRK07190  145 TLSNGERIQSRYVIGADGSRSFVRNHFNVP 174
PRK02106 PRK02106
choline dehydrogenase; Validated
 45-84 2.67e-03

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 40.20  E-value: 2.67e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2008076678  45 KNEVYDIIISGGGMVGSAMACSLGMDRNlegKKILLLEAG 84
Cdd:PRK02106    2 TTMEYDYIIIGAGSAGCVLANRLSEDPD---VSVLLLEAG 38
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 46-97 2.99e-03

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 40.20  E-value: 2.99e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2008076678  46 NEVYDIIISGGGMVGSAMACSLGMDrnlEGKKILLLEAG--NKKVMHKVPDTYS 97
Cdd:COG2303     2 LEEYDYVIVGAGSAGCVLANRLSED---AGLRVLLLEAGgrDDDPLIRMPAGYA 52
PRK06185 PRK06185
FAD-dependent oxidoreductase;
203-431 7.28e-03

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 38.69  E-value: 7.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 203 VKVTLASGE-SVETKLLIGADGPNSMVRQELGIPTVKwnydQSAVVAVL--HLS-EPTENNVAWQRFLPSGPIAMLPLSD 278
Cdd:PRK06185  145 VRARTPDGPgEIRADLVVGADGRHSRVRALAGLEVRE----FGAPMDVLwfRLPrEPDDPESLMGRFGPGQGLIMIDRGD 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 279 tesslVWSTSH----QQAQELleldeesfvdainsafwsnenqselieTAGSL--FRSTLSAIMPsagsprQLPPSVAGI 352
Cdd:PRK06185  221 -----YWQCGYvipkGGYAAL---------------------------RAAGLeaFRERVAELAP------ELADRVAEL 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2008076678 353 GPKSRVKF-PLGIGHASEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVACLTRILSQAAFDGKDLGAmqHLLEYETERQ 431
Cdd:PRK06185  263 KSWDDVKLlDVRVDRLRRWHRPGLLCIGDAAHAMSPVGGVGINLAIQDAVAAANILAEPLRRGRVSDR--DLAAVQRRRE 340
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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