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Conserved domains on  [gi|1953050669|ref|XP_038437637|]
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pericentrin isoform X5 [Canis lupus familiaris]

Protein Classification

ClyA-like and PACT_coil_coil domain-containing protein( domain architecture ID 13380129)

protein containing domains Smc, SMC_prok_B, ClyA-like, and PACT_coil_coil

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3036-3114 8.02e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


:

Pssm-ID: 463115  Cd Length: 77  Bit Score: 103.06  E-value: 8.02e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953050669 3036 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAdkkTTTSRPFTRFRTAVRVVIAILRLRFLVKKW 3114
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD---RPSRKPRRKLKSAALAVIAIARMKRLAREW 77
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2468-3024 8.42e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.17  E-value: 8.42e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2468 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAQlRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVELLAYKV 2547
Cdd:COG1196    188 LERLEDILGELERQLEPL----------ERQAEKAE-RYRELKEELKELEAELLLLKLRELEAELE-ELEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2548 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAA 2627
Cdd:COG1196    256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2628 LQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLcVALKHEQTAKDNLQKELQIEASRCEA 2707
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL-LEALRAAAELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2708 LLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRgprespAHHALLRKLKEEKSRAAELQARLEQVQRQQEA 2787
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE------EEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2788 DVQKRRAELEREKEVRAaqarepgrclRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKeklR 2867
Cdd:COG1196    489 AAARLLLLLEAEADYEG----------FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE---D 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2868 ELELQRQRDEHKIRQLQR-TVQALEAKEEAAQRPEAERLQEERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNE 2946
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRaTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953050669 2947 KAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRR 3024
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1365-1901 4.55e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 88.84  E-value: 4.55e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1365 QEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEF 1444
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1445 QREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCR 1524
Cdd:COG1196    322 EEELAELEEELEELEE---------ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1525 REAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcpvppadscpegpeVQLEAVQRALQQRESEV 1604
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE--------------EALEEAAEEEAELEEEE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1605 LDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGmgsgalR 1684
Cdd:COG1196    459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG------V 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1685 EVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVPAA------------VDCELPAVP 1752
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAlargaigaavdlVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1753 APA-----------VGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMAS-- 1819
Cdd:COG1196    613 ARYyvlgdtllgrtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEee 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1820 -----QIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRL 1894
Cdd:COG1196    693 leleeALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772


                   ....*..
gi 1953050669 1895 SRQLQVL 1901
Cdd:COG1196    773 EREIEAL 779
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 139-698 7.69e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.60  E-value: 7.69e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  139 ELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLrcsQET 218
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---AEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  219 AKLKEKLQSEMERNARAVESLKRdweserglclENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECAL 298
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEE----------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  299 RTLEAQHEEALRQLREDLQSERCQYVQDLELRLRDQEVEKQLE-LESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDA 377
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  378 SARTphgEELEQRERECGVQQQRRGRRAEQESELGQSPEGAVERGRedpvLLEQRLQDATEEPSLESGGIGPSSMREGER 457
Cdd:COG1196    448 AEEE---AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA----ARLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  458 REQRVGPSLQPELAEnhrcHLTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTE---V 534
Cdd:COG1196    521 GLAGAVAVLIGVEAA----YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALargA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  535 VARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERV------------------KHSLVEDHR 596
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVtlegeggsaggsltggsrRELLAALLE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  597 EELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQIL 676
Cdd:COG1196    677 AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756

                          570       580
                   ....*....|....*....|..
gi 1953050669  677 DLEGSLVEQQGRLRQLEHGLEA 698
Cdd:COG1196    757 PEPPDLEELERELERLEREIEA 778
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 566-1066 2.39e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 2.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  566 ENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAE--EELTLMLHDLK 643
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEErlEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  644 EQAEAEKQSVINKfELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcgqepAGRVAPADQDWE 723
Cdd:COG1196    330 EELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA-----------EELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  724 LATRRLREDCALQ-LMQAQSRFLKERKELTEKFTAEQDAL--LQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEV 800
Cdd:COG1196    398 LAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEeeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  801 EELKASVESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEKEAS 880
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  881 HPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQ 960
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  961 LHCQEEPEVLECPSEPFLEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQIL 1040
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          490       500
                   ....*....|....*....|....*.
gi 1953050669 1041 SLSHEVEERRRDLEQLQQRRERENQE 1066
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1186-1518 1.20e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 1.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1186 SSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLM 1265
Cdd:TIGR02168  671 SILERRREIEE----LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1266 LELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAGT 1345
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1346 pAPIAHEDSALRREVECLtQEQSEARKQSEKDRAALLSQMKVFEAELEEQLsrheacakqaEELSALRQQMAALDKHLRS 1425
Cdd:TIGR02168  827 -ESLERRIAATERRLEDL-EEQIEELSEDIESLAAEIEELEELIEELESEL----------EALLNERASLEEALALLRS 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1426 QRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREK-SDGFNELVIKKELADR 1504
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEySLTLEEAEALENKIED 965

                          330
                   ....*....|....
gi 1953050669 1505 QVMIQEEEIRRLEE 1518
Cdd:TIGR02168  966 DEEEARRRLKRLEN 979
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3036-3114 8.02e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 103.06  E-value: 8.02e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953050669 3036 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAdkkTTTSRPFTRFRTAVRVVIAILRLRFLVKKW 3114
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD---RPSRKPRRKLKSAALAVIAIARMKRLAREW 77
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2468-3024 8.42e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.17  E-value: 8.42e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2468 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAQlRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVELLAYKV 2547
Cdd:COG1196    188 LERLEDILGELERQLEPL----------ERQAEKAE-RYRELKEELKELEAELLLLKLRELEAELE-ELEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2548 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAA 2627
Cdd:COG1196    256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2628 LQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLcVALKHEQTAKDNLQKELQIEASRCEA 2707
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL-LEALRAAAELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2708 LLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRgprespAHHALLRKLKEEKSRAAELQARLEQVQRQQEA 2787
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE------EEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2788 DVQKRRAELEREKEVRAaqarepgrclRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKeklR 2867
Cdd:COG1196    489 AAARLLLLLEAEADYEG----------FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE---D 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2868 ELELQRQRDEHKIRQLQR-TVQALEAKEEAAQRPEAERLQEERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNE 2946
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRaTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953050669 2947 KAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRR 3024
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1365-1901 4.55e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 88.84  E-value: 4.55e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1365 QEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEF 1444
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1445 QREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCR 1524
Cdd:COG1196    322 EEELAELEEELEELEE---------ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1525 REAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcpvppadscpegpeVQLEAVQRALQQRESEV 1604
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE--------------EALEEAAEEEAELEEEE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1605 LDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGmgsgalR 1684
Cdd:COG1196    459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG------V 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1685 EVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVPAA------------VDCELPAVP 1752
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAlargaigaavdlVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1753 APA-----------VGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMAS-- 1819
Cdd:COG1196    613 ARYyvlgdtllgrtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEee 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1820 -----QIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRL 1894
Cdd:COG1196    693 leleeALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772


                   ....*..
gi 1953050669 1895 SRQLQVL 1901
Cdd:COG1196    773 EREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 139-698 7.69e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.60  E-value: 7.69e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  139 ELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLrcsQET 218
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---AEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  219 AKLKEKLQSEMERNARAVESLKRdweserglclENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECAL 298
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEE----------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  299 RTLEAQHEEALRQLREDLQSERCQYVQDLELRLRDQEVEKQLE-LESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDA 377
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  378 SARTphgEELEQRERECGVQQQRRGRRAEQESELGQSPEGAVERGRedpvLLEQRLQDATEEPSLESGGIGPSSMREGER 457
Cdd:COG1196    448 AEEE---AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA----ARLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  458 REQRVGPSLQPELAEnhrcHLTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTE---V 534
Cdd:COG1196    521 GLAGAVAVLIGVEAA----YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALargA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  535 VARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERV------------------KHSLVEDHR 596
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVtlegeggsaggsltggsrRELLAALLE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  597 EELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQIL 676
Cdd:COG1196    677 AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756

                          570       580
                   ....*....|....*....|..
gi 1953050669  677 DLEGSLVEQQGRLRQLEHGLEA 698
Cdd:COG1196    757 PEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1369-1734 1.77e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.57  E-value: 1.77e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1369 EARKQSEKDRAALlSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHL--------RSQRQFMDEQAVEREHE 1440
Cdd:TIGR02168  176 ETERKLERTRENL-DRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALlvlrleelREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1441 REEFQREIQRLEEQLrqaarprphgprvsdeEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETN 1520
Cdd:TIGR02168  255 LEELTAELQELEEKL----------------EELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1521 ASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSnlllvstLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRALQQR 1600
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELES-------LEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1601 ESEVLDLKEQLGkmkddlvsksdevlhlnlELDAQSSRAAVSVRELQEENASLKAFLQNKEKeimcvsEQLEAQLAGMGS 1680
Cdd:TIGR02168  392 ELQIASLNNEIE------------------RLEARLERLEDRRERLQQEIEELLKKLEEAEL------KELQAELEELEE 447

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1953050669 1681 gALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEME--QLHEVIERLQEELS 1734
Cdd:TIGR02168  448 -ELEELQEELERLEEALEELREELEEAEQALDAAERELAQlqARLDSLERLQENLE 502
PTZ00121 PTZ00121
MAEBL; Provisional
 2477-2918 2.00e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.02  E-value: 2.00e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2477 EQEKSLEHLRASDRSSLLSEIQalRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAykveQEKRIASD 2556
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVK--KAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA----EEARKADE 1282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2557 VQKTltEEQEKASSVRKLLVVEQTVVRDLRSELR----ECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELE 2632
Cdd:PTZ00121  1283 LKKA--EEKKKADEAKKAEEKKKADEAKKKAEEAkkadEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE 1360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2633 SERGKERALQSRLEEAQ--LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLA 2710
Cdd:PTZ00121  1361 AAEEKAEAAEKKKEEAKkkADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2711 QERGQLSELQRslEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEAdvq 2790
Cdd:PTZ00121  1441 EEAKKADEAKK--KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA--- 1515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2791 KRRAELEREKEVRAAQAREPGRCLRReghaSQQQAGLEPLQAglaAQEGRKDARRADVGPGRADAEMRPTGAK--EKLRE 2868
Cdd:PTZ00121  1516 KKAEEAKKADEAKKAEEAKKADEAKK----AEEKKKADELKK---AEELKKAEEKKKAEEAKKAEEDKNMALRkaEEAKK 1588

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1953050669 2869 LELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERL---QEERLGLERVRQQ 2918
Cdd:PTZ00121  1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkaEEEKKKVEQLKKK 1641
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2468-2808 6.36e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.01  E-value: 6.36e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2468 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAqlrmthlqnqEKLQQLCAALTSAEARgsrqehqlrrqveLLAYKV 2547
Cdd:TIGR02168  188 LDRLEDILNELERQLKSL----------ERQAEKA----------ERYKELKAELRELELA-------------LLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2548 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQdnerllaSLGEAQKEVLQLRSVLDSKESNLRAA 2627
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE-------EIEELQKELYALANEISRLEQQKQIL 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2628 LQELESergkeraLQSRLEEAQLQhLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEA 2707
Cdd:TIGR02168  308 RERLAN-------LERQLEELEAQ-LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2708 LLAQERGQLSELQRSLEAEKGRSLELAAAL-----RHERLLTEQLSRGPR-ESPAHHALLRKLKEEKSRAAELQARLEQV 2781
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLerledRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERL 459

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1953050669 2782 QRQ----QEADVQKRRAELEREKEVRAAQAR 2808
Cdd:TIGR02168  460 EEAleelREELEEAEQALDAAERELAQLQAR 490
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 566-1066 2.39e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 2.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  566 ENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAE--EELTLMLHDLK 643
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEErlEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  644 EQAEAEKQSVINKfELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcgqepAGRVAPADQDWE 723
Cdd:COG1196    330 EELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA-----------EELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  724 LATRRLREDCALQ-LMQAQSRFLKERKELTEKFTAEQDAL--LQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEV 800
Cdd:COG1196    398 LAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEeeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  801 EELKASVESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEKEAS 880
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  881 HPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQ 960
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  961 LHCQEEPEVLECPSEPFLEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQIL 1040
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          490       500
                   ....*....|....*....|....*.
gi 1953050669 1041 SLSHEVEERRRDLEQLQQRRERENQE 1066
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1186-1518 1.20e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 1.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1186 SSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLM 1265
Cdd:TIGR02168  671 SILERRREIEE----LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1266 LELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAGT 1345
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1346 pAPIAHEDSALRREVECLtQEQSEARKQSEKDRAALLSQMKVFEAELEEQLsrheacakqaEELSALRQQMAALDKHLRS 1425
Cdd:TIGR02168  827 -ESLERRIAATERRLEDL-EEQIEELSEDIESLAAEIEELEELIEELESEL----------EALLNERASLEEALALLRS 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1426 QRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREK-SDGFNELVIKKELADR 1504
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEySLTLEEAEALENKIED 965

                          330
                   ....*....|....
gi 1953050669 1505 QVMIQEEEIRRLEE 1518
Cdd:TIGR02168  966 DEEEARRRLKRLEN 979
PTZ00121 PTZ00121
MAEBL; Provisional
 172-876 7.55e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 7.55e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  172 ELRAMLNGRHAQELALLRSRQQQElELAREQHAREQEEMR----LRCSQETAKLKEKLQSEMERNARAVESLKRDWESER 247
Cdd:PTZ00121  1150 DAKRVEIARKAEDARKAEEARKAE-DAKKAEAARKAEEVRkaeeLRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEA 1228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  248 GLCLENLRRELSAKHRSELENLQDQFkRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERCQYVQDL 327
Cdd:PTZ00121  1229 VKKAEEAKKDAEEAKKAEEERNNEEI-RKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  328 ----ELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDASARTPHGEELEQRErecgvqQQRRGR 403
Cdd:PTZ00121  1308 kkkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE------AKKKAD 1381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  404 RAEQESELGQSPEGAVERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERREQRvgpslqpelAENHRchltawtS 483
Cdd:PTZ00121  1382 AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKK---------AEEAK-------K 1445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  484 SLEAQQQAGlvETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEvvarglglEAEHRLKLLLLQTELKEEMDvl 563
Cdd:PTZ00121  1446 ADEAKKKAE--EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE--------EAKKKADEAKKAAEAKKKAD-- 1513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  564 klENRNLHEKLQHEVCLKEDLERVKHSLVEdhREELKKANErlqlVKQELKDKEAEWKVASEDlKRKAEEELTLMLHDLK 643
Cdd:PTZ00121  1514 --EAKKAEEAKKADEAKKAEEAKKADEAKK--AEEKKKADE----LKKAEELKKAEEKKKAEE-AKKAEEDKNMALRKAE 1584

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  644 EQAEAEKQSVINKFELREiKMRQLQDQQAAQildlegslvEQQGRLRQLEHGLEAEECPRCGHCGQEPAGRVAPADQdwe 723
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYE-EEKKMKAEEAKK---------AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE--- 1651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  724 laTRRLREDCALQLMQAQSRFLKERKELTEKFTAEQD------ALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRR 797
Cdd:PTZ00121  1652 --LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDekkaaeALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK 1729

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953050669  798 AEVEELKASVESERWALAEARVAELQTEHAAAISALEARHSallgslESRHLSEVQAMREEHRQALEQLRVDLEKQLQE 876
Cdd:PTZ00121  1730 IKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA------EEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
PTZ00121 PTZ00121
MAEBL; Provisional
 1217-1888 1.62e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.93  E-value: 1.62e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1217 RQLEEARQIHSRFEKEFSCKNEET--AQVVRKQQQL-----LERLEE----ENAARTRLMLELHQAQGIIEGFKEEKASL 1285
Cdd:PTZ00121  1158 RKAEDARKAEEARKAEDAKKAEAArkAEEVRKAEELrkaedARKAEAarkaEEERKAEEARKAEDAKKAEAVKKAEEAKK 1237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1286 QEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENsalwSQKEASAAEAEAREAGTPAPIAHEdsalRREVECLTQ 1365
Cdd:PTZ00121  1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE----ARKADELKKAEEKKKADEAKKAEE----KKKADEAKK 1309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1366 EQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQfmDEQAVEREHEREEFQ 1445
Cdd:PTZ00121  1310 KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK--KEEAKKKADAAKKKA 1387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1446 REIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKSDGfNELVIKKELADR--QVMIQEEEIRRLEETN--A 1521
Cdd:PTZ00121  1388 EEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA-DEAKKKAEEAKKadEAKKKAEEAKKAEEAKkkA 1466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1522 SCRREAAQLREELERQRDAMKALQQDKEAlqEKQMSNLLLVSTLQSKLDEGRcpvppadscpegpevQLEAVQRALQQRE 1601
Cdd:PTZ00121  1467 EEAKKADEAKKKAEEAKKADEAKKKAEEA--KKKADEAKKAAEAKKKADEAK---------------KAEEAKKADEAKK 1529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1602 SEVLDLKEQLGKMKDdlVSKSDEVlhlnleLDAQSSRAAVSVRELQE-ENASLKAFLQNKEKEIMCVSEQLEAQLAGMGS 1680
Cdd:PTZ00121  1530 AEEAKKADEAKKAEE--KKKADEL------KKAEELKKAEEKKKAEEaKKAEEDKNMALRKAEEAKKAEEARIEEVMKLY 1601

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1681 GALREVTYDRSSEIEELRSIIENLRenqqrlqkeKAEEMEQLHEVIERLQEELSLGAPAVPAAVDCELPAVPAPAVGPEA 1760
Cdd:PTZ00121  1602 EEEKKMKAEEAKKAEEAKIKAEELK---------KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE 1672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1761 LAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQamaSQIQAFEAALRAKEARLAERDL 1840
Cdd:PTZ00121  1673 DKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEE---NKIKAEEAKKEAEEDKKKAEEA 1749

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*....
gi 1953050669 1841 EIDAMKRQKLAHSAELETILAAFSRF-RRTLERQPLAAEDEPPELQRLR 1888
Cdd:PTZ00121  1750 KKDEEEKKKIAHLKKEEEKKAEEIRKeKEAVIEEELDEEDEKRRMEVDK 1798
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1351-1564 1.13e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 54.74  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1351 HEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEE-QLSRHEACAKQAEELSALRQQMAALDKHLRSQRQF 1429
Cdd:pfam17380  339 QERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERlQMERQQKNERVRQELEAARKVKILEEERQRKIQQQ 418

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1430 MDEQAVEREHEREEFQREIQRLEEQ-------LRQAARPRPHGP---RVSDEEQLDEEVELLQEKL-REKSDGFNELVIK 1498
Cdd:pfam17380  419 KVEMEQIRAEQEEARQREVRRLEEEraremerVRLEEQERQQQVerlRQQEEERKRKKLELEKEKRdRKRAEEQRRKILE 498

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953050669 1499 KEL-ADRQVMIQEEEIRRLEETNASCRREAAQlreELERQRDAMKALQQDKEALQEKQMSNLLLVST 1564
Cdd:pfam17380  499 KELeERKQAMIEEERKRKLLEKEMEERQKAIY---EEERRREAEEERRKQQEMEERRRIQEQMRKAT 562
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 156-441 1.25e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 54.36  E-value: 1.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  156 ELTQANLQKEKETALTEL--RAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNA 233
Cdd:pfam17380  295 KMEQERLRQEKEEKAREVerRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEI 374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  234 RAVESLKRdWESERGLCLENLRRELSAKHRSELenLQDQFKRELSEQKAELEKI-FQAKNQAECALRTLEAQHEEALRQL 312
Cdd:pfam17380  375 SRMRELER-LQMERQQKNERVRQELEAARKVKI--LEEERQRKIQQQKVEMEQIrAEQEEARQREVRRLEEERAREMERV 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  313 REDLQsERCQYVQdlelRLRDQEVE---KQLELESLRasyaELKAQSQEEIRRLWSQLESPRPDRQDASARTPHGEELEQ 389
Cdd:pfam17380  452 RLEEQ-ERQQQVE----RLRQQEEErkrKKLELEKEK----RDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEM 522

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1953050669  390 RERECGVQQQRRGRRAEQESELGQSPEgavERGRedpvlLEQRLQDATEEPS 441
Cdd:pfam17380  523 EERQKAIYEEERRREAEEERRKQQEME---ERRR-----IQEQMRKATEERS 566
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 169-439 2.23e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 2.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  169 ALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAvESLKRDWESERG 248
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI-EQLEQEEEKLKE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  249 LcLENLRRELSAKHRsELENLqdqfKRELSEQKAELEKIFQAKNQAECALRTLEAQ-HEEALRQLREDLQSERcQYVQDL 327
Cdd:TIGR02169  738 R-LEELEEDLSSLEQ-EIENV----KSELKELEARIEELEEDLHKLEEALNDLEARlSHSRIPEIQAELSKLE-EEVSRI 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  328 ELRLrdQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS----------ARTPHGEELEQRERECGVQ 397
Cdd:TIGR02169  811 EARL--REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLngkkeeleeeLEELEAALRDLESRLGDLK 888

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1953050669  398 QQRRGRRA---EQESELGQSpEGAVERGREDPVLLEQRLQDATEE 439
Cdd:TIGR02169  889 KERDELEAqlrELERKIEEL-EAQIEKKRKRLSELKAKLEALEEE 932
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2480-2908 2.30e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.14  E-value: 2.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2480 KSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRR-----------QVELLAYKVE 2548
Cdd:pfam12128  268 KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEAledqhgafldaDIETAAADQE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2549 QEKRIASDVQ------KTLTEEQ---EKASSVRKLLVVEQ--TVVRDLRSELRECKQDNERLLASL-GEAQKEVLQLRSV 2616
Cdd:pfam12128  348 QLPSWQSELEnleerlKALTGKHqdvTAKYNRRRSKIKEQnnRDIAGIKDKLAKIREARDRQLAVAeDDLQALESELREQ 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2617 LDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREgQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQK 2696
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLE-NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASE 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2697 ELQieasRCEALLAQERGQLSELQRSLEAEKGRSLE----------------LAAALRHERLLTEQLSRGPR-------- 2752
Cdd:pfam12128  507 ALR----QASRRLEERQSALDELELQLFPQAGTLLHflrkeapdweqsigkvISPELLHRTDLDPEVWDGSVggelnlyg 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2753 --------ESPAHHALLRKLKEEKSRAAE-LQARLEQVQRQQEADVQKRRA-ELEREKEVRAAQAREPGRcLRREGHASQ 2822
Cdd:pfam12128  583 vkldlkriDVPEWAASEEELRERLDKAEEaLQSAREKQAAAEEQLVQANGElEKASREETFARTALKNAR-LDLRRLFDE 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2823 QQAGLEPLQAGLAAQEGRKDARRADVgpgraDAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEA 2902
Cdd:pfam12128  662 KQSEKDKKNKALAERKDSANERLNSL-----EAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKA 736


                   ....*.
gi 1953050669 2903 ERLQEE 2908
Cdd:pfam12128  737 AIAARR 742
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1252-1466 2.65e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1252 ERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQK 1331
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1332 EASAAEAEAR--------EAGTPAPIAHEDSALR-----REVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSR 1398
Cdd:COG4942    100 EAQKEELAELlralyrlgRQPPLALLLSPEDFLDavrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953050669 1399 HEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGP 1466
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3036-3114 8.02e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 103.06  E-value: 8.02e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953050669 3036 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAdkkTTTSRPFTRFRTAVRVVIAILRLRFLVKKW 3114
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD---RPSRKPRRKLKSAALAVIAIARMKRLAREW 77
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2468-3024 8.42e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.17  E-value: 8.42e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2468 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAQlRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVELLAYKV 2547
Cdd:COG1196    188 LERLEDILGELERQLEPL----------ERQAEKAE-RYRELKEELKELEAELLLLKLRELEAELE-ELEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2548 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAA 2627
Cdd:COG1196    256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2628 LQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLcVALKHEQTAKDNLQKELQIEASRCEA 2707
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL-LEALRAAAELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2708 LLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRgprespAHHALLRKLKEEKSRAAELQARLEQVQRQQEA 2787
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE------EEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2788 DVQKRRAELEREKEVRAaqarepgrclRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKeklR 2867
Cdd:COG1196    489 AAARLLLLLEAEADYEG----------FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE---D 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2868 ELELQRQRDEHKIRQLQR-TVQALEAKEEAAQRPEAERLQEERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNE 2946
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRaTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953050669 2947 KAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRR 3024
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2463-2920 2.24e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.00  E-value: 2.24e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2463 EHSSLLERLEKVVQEQEKSLEHLRAS--DRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQV 2540
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLEleELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2541 ELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSvLDSK 2620
Cdd:COG1196    330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-LEEA 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2621 ESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQI 2700
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2701 EASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQ 2780
Cdd:COG1196    489 AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2781 -----VQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQQQAGLEPLQAGLAA--------QEGRKDARRAD 2847
Cdd:COG1196    569 akagrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAarleaalrRAVTLAGRLRE 648

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1953050669 2848 VGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERLGLERVRQQLL 2920
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1365-1901 4.55e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 88.84  E-value: 4.55e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1365 QEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEF 1444
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1445 QREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCR 1524
Cdd:COG1196    322 EEELAELEEELEELEE---------ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1525 REAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcpvppadscpegpeVQLEAVQRALQQRESEV 1604
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE--------------EALEEAAEEEAELEEEE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1605 LDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGmgsgalR 1684
Cdd:COG1196    459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG------V 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1685 EVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVPAA------------VDCELPAVP 1752
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAlargaigaavdlVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1753 APA-----------VGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMAS-- 1819
Cdd:COG1196    613 ARYyvlgdtllgrtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEee 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1820 -----QIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRL 1894
Cdd:COG1196    693 leleeALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772


                   ....*..
gi 1953050669 1895 SRQLQVL 1901
Cdd:COG1196    773 EREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 139-698 7.69e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.60  E-value: 7.69e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  139 ELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLrcsQET 218
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---AEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  219 AKLKEKLQSEMERNARAVESLKRdweserglclENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECAL 298
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEE----------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  299 RTLEAQHEEALRQLREDLQSERCQYVQDLELRLRDQEVEKQLE-LESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDA 377
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  378 SARTphgEELEQRERECGVQQQRRGRRAEQESELGQSPEGAVERGRedpvLLEQRLQDATEEPSLESGGIGPSSMREGER 457
Cdd:COG1196    448 AEEE---AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA----ARLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  458 REQRVGPSLQPELAEnhrcHLTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTE---V 534
Cdd:COG1196    521 GLAGAVAVLIGVEAA----YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALargA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  535 VARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERV------------------KHSLVEDHR 596
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVtlegeggsaggsltggsrRELLAALLE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  597 EELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQIL 676
Cdd:COG1196    677 AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756

                          570       580
                   ....*....|....*....|..
gi 1953050669  677 DLEGSLVEQQGRLRQLEHGLEA 698
Cdd:COG1196    757 PEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1369-1734 1.77e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.57  E-value: 1.77e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1369 EARKQSEKDRAALlSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHL--------RSQRQFMDEQAVEREHE 1440
Cdd:TIGR02168  176 ETERKLERTRENL-DRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALlvlrleelREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1441 REEFQREIQRLEEQLrqaarprphgprvsdeEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETN 1520
Cdd:TIGR02168  255 LEELTAELQELEEKL----------------EELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1521 ASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSnlllvstLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRALQQR 1600
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELES-------LEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1601 ESEVLDLKEQLGkmkddlvsksdevlhlnlELDAQSSRAAVSVRELQEENASLKAFLQNKEKeimcvsEQLEAQLAGMGS 1680
Cdd:TIGR02168  392 ELQIASLNNEIE------------------RLEARLERLEDRRERLQQEIEELLKKLEEAEL------KELQAELEELEE 447

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1953050669 1681 gALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEME--QLHEVIERLQEELS 1734
Cdd:TIGR02168  448 -ELEELQEELERLEEALEELREELEEAEQALDAAERELAQlqARLDSLERLQENLE 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1199-1745 1.08e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 1.08e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1199 QSLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGF 1278
Cdd:COG1196    228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1279 KEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAreagtpapIAHEDSALRR 1358
Cdd:COG1196    308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE--------AEAELAEAEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1359 EVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVERE 1438
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1439 HEREEFQREIQRLEEQLRQAArprphgpRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQ--------VMIQE 1510
Cdd:COG1196    460 ALLELLAELLEEAALLEAALA-------ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavaVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1511 EEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcPVPPADSCPEGPEVQL 1590
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARG-AIGAAVDLVASDLREA 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1591 EAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEimcvsEQ 1670
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL-----AE 686

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953050669 1671 LEAQLAGMGSGALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVPAAVD 1745
Cdd:COG1196    687 RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761
PTZ00121 PTZ00121
MAEBL; Provisional
 2477-2918 2.00e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.02  E-value: 2.00e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2477 EQEKSLEHLRASDRSSLLSEIQalRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAykveQEKRIASD 2556
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVK--KAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA----EEARKADE 1282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2557 VQKTltEEQEKASSVRKLLVVEQTVVRDLRSELR----ECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELE 2632
Cdd:PTZ00121  1283 LKKA--EEKKKADEAKKAEEKKKADEAKKKAEEAkkadEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE 1360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2633 SERGKERALQSRLEEAQ--LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLA 2710
Cdd:PTZ00121  1361 AAEEKAEAAEKKKEEAKkkADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2711 QERGQLSELQRslEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEAdvq 2790
Cdd:PTZ00121  1441 EEAKKADEAKK--KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA--- 1515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2791 KRRAELEREKEVRAAQAREPGRCLRReghaSQQQAGLEPLQAglaAQEGRKDARRADVGPGRADAEMRPTGAK--EKLRE 2868
Cdd:PTZ00121  1516 KKAEEAKKADEAKKAEEAKKADEAKK----AEEKKKADELKK---AEELKKAEEKKKAEEAKKAEEDKNMALRkaEEAKK 1588

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1953050669 2869 LELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERL---QEERLGLERVRQQ 2918
Cdd:PTZ00121  1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkaEEEKKKVEQLKKK 1641
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2468-2808 6.36e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.01  E-value: 6.36e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2468 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAqlrmthlqnqEKLQQLCAALTSAEARgsrqehqlrrqveLLAYKV 2547
Cdd:TIGR02168  188 LDRLEDILNELERQLKSL----------ERQAEKA----------ERYKELKAELRELELA-------------LLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2548 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQdnerllaSLGEAQKEVLQLRSVLDSKESNLRAA 2627
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE-------EIEELQKELYALANEISRLEQQKQIL 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2628 LQELESergkeraLQSRLEEAQLQhLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEA 2707
Cdd:TIGR02168  308 RERLAN-------LERQLEELEAQ-LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2708 LLAQERGQLSELQRSLEAEKGRSLELAAAL-----RHERLLTEQLSRGPR-ESPAHHALLRKLKEEKSRAAELQARLEQV 2781
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLerledRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERL 459

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1953050669 2782 QRQ----QEADVQKRRAELEREKEVRAAQAR 2808
Cdd:TIGR02168  460 EEAleelREELEEAEQALDAAERELAQLQAR 490
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1255-1925 1.17e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.24  E-value: 1.17e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1255 EEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEAS 1334
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1335 AAEAEAreagtpapIAHEDSALRREVECLTQEQSEARKQSEKDRAALLSQmkvfEAELEEQLSRHEACAKQAEELSALRQ 1414
Cdd:TIGR02168  301 EQQKQI--------LRERLANLERQLEELEAQLEELESKLDELAEELAEL----EEKLEELKEELESLEAELEELEAELE 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1415 QMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAA--RPRPHGPRVSDEEQLDE-EVELLQEKLREKSDG 1491
Cdd:TIGR02168  369 ELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEdrRERLQQEIEELLKKLEEaELKELQAELEELEEE 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1492 FNELVIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREELerqrDAMKALQQDKEALQEkQMSNLLLVstlQSKLDE 1571
Cdd:TIGR02168  449 LEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL----DSLERLQENLEGFSE-GVKALLKN---QSGLSG 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1572 GRCPVPPADSCPEGPEVQLEAVqralqqresevldlkeqLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVREL----- 1646
Cdd:TIGR02168  521 ILGVLSELISVDEGYEAAIEAA-----------------LGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLdsikg 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1647 QEENASLKAFLQNKE------KEIMCVSEQLEAQLAGMGSGAL-------------------REVTYD------------ 1689
Cdd:TIGR02168  584 TEIQGNDREILKNIEgflgvaKDLVKFDPKLRKALSYLLGGVLvvddldnalelakklrpgyRIVTLDgdlvrpggvitg 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1690 ----RSSEIEELRSIIENLRENQQRLQkekaEEMEQLHEVIERLQEELSLGAPAVPAAVDCELPAVPAPAVGPEALAAAG 1765
Cdd:TIGR02168  664 gsakTNSSILERRREIEELEEKIEELE----EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE 739

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1766 AASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALR---EAEVQAMASQIQAFEAALRAKEARLAERDLEI 1842
Cdd:TIGR02168  740 AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIeelEAQIEQLKEELKALREALDELRAELTLLNEEA 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1843 DAMKRQKLAHSAELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRLSRQLQVLnqrflrcQKEADKQQARGARL 1922
Cdd:TIGR02168  820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL-------LNERASLEEALALL 892


                   ...
gi 1953050669 1923 RPR 1925
Cdd:TIGR02168  893 RSE 895
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 566-1066 2.39e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 2.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  566 ENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAE--EELTLMLHDLK 643
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEErlEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  644 EQAEAEKQSVINKfELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcgqepAGRVAPADQDWE 723
Cdd:COG1196    330 EELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA-----------EELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  724 LATRRLREDCALQ-LMQAQSRFLKERKELTEKFTAEQDAL--LQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEV 800
Cdd:COG1196    398 LAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEeeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  801 EELKASVESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEKEAS 880
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  881 HPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQ 960
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  961 LHCQEEPEVLECPSEPFLEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQIL 1040
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          490       500
                   ....*....|....*....|....*.
gi 1953050669 1041 SLSHEVEERRRDLEQLQQRRERENQE 1066
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLE 743
PTZ00121 PTZ00121
MAEBL; Provisional
 2526-2909 2.54e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.09  E-value: 2.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2526 EARGSRQEHQLRRQVELLAYKVEqEKRIASDVQKTLTEEQEKASSVRKllvveQTVVRDLRSELRECKQDNERLLASLGE 2605
Cdd:PTZ00121  1458 KAEEAKKKAEEAKKADEAKKKAE-EAKKADEAKKKAEEAKKKADEAKK-----AAEAKKKADEAKKAEEAKKADEAKKAE 1531

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2606 AQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQlcvALK 2685
Cdd:PTZ00121  1532 EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK---KMK 1608

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2686 HEQTAKDNLQKELQIEASRCEallaQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLK 2765
Cdd:PTZ00121  1609 AEEAKKAEEAKIKAEELKKAE----EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2766 EEKSRAAELQAR-------LEQVQRQQEADVQKRRaELEREKEVRAAQAREpgrcLRREGHASQQQagleplqaglaAQE 2838
Cdd:PTZ00121  1685 EDEKKAAEALKKeaeeakkAEELKKKEAEEKKKAE-ELKKAEEENKIKAEE----AKKEAEEDKKK-----------AEE 1748

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953050669 2839 GRKDarradvgpgradaemrpTGAKEKLRELELQRQRDEHKIRQLQRTVqaleAKEEAAQRPEAERLQEER 2909
Cdd:PTZ00121  1749 AKKD-----------------EEEKKKIAHLKKEEEKKAEEIRKEKEAV----IEEELDEEDEKRRMEVDK 1798
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1218-1732 4.14e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 4.14e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1218 QLEEARQIHSRFEKEFSCKNEETAQVVRKQQQL-------LERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALC 1290
Cdd:COG1196    268 ELEELRLELEELELELEEAQAEEYELLAELARLeqdiarlEERRRELEERLEELEEELAELEEELEELEEELEELEEELE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1291 RQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAGTPAPIAHEDSALRREVEcLTQEQSEA 1370
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER-LEEELEEL 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1371 RKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVER------EHEREEF 1444
Cdd:COG1196    427 EEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLlllleaEADYEGF 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1445 QREIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVE-----LLQEKLREKSDGFNELV--IKKELADRQVMIQEEEIRRLE 1517
Cdd:COG1196    507 LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEaalaaALQNIVVEDDEVAAAAIeyLKAAKAGRATFLPLDKIRARA 586

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1518 ETNASCRR----EAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRCPVPPADscpEGPEVQLEAV 1593
Cdd:COG1196    587 ALAAALARgaigAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEG---EGGSAGGSLT 663

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1594 QRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEA 1673
Cdd:COG1196    664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1674 QLAGMGSGALREVTYDRS-----SEIEELRSIIENL-----------RENQQR---LQKEKA---EEMEQLHEVIERLQE 1731
Cdd:COG1196    744 EEELLEEEALEELPEPPDleeleRELERLEREIEALgpvnllaieeyEELEERydfLSEQREdleEARETLEEAIEEIDR 823


                   .
gi 1953050669 1732 E 1732
Cdd:COG1196    824 E 824
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2466-3030 6.13e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 6.13e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2466 SLLERLEKVvQEQEKSLEHLRASdRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAY 2545
Cdd:TIGR02168  236 ELREELEEL-QEELKEAEEELEE-LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2546 KVEQEKRIASD---VQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKE- 2621
Cdd:TIGR02168  314 LERQLEELEAQleeLESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEl 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2622 ---------SNLRAALQELESERGKER----ALQSRLEEAQLQHLQRE-GQSSKTLEELRASLEKQFAQSSQLCVALKHE 2687
Cdd:TIGR02168  394 qiaslnneiERLEARLERLEDRRERLQqeieELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2688 QTAKDNLQKELQIEASRCEALLAQER--------------------GQLSELQRSLEAEKGRSLELAAALRhERLL---- 2743
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQEnlegfsegvkallknqsglsGILGVLSELISVDEGYEAAIEAALG-GRLQavvv 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2744 -TEQLSRGPRESPAHHALLRK--LKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHA 2820
Cdd:TIGR02168  553 eNLNAAKKAIAFLKQNELGRVtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLD 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2821 S-QQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQr 2899
Cdd:TIGR02168  633 NaLELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELE- 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2900 peaERLQEERLGLERVRQQLLCAAGLLTSFisRTVDRTISDWTSSNEKAVTSLLHTLEELKSELSTPSSSQKKMTAELQT 2979
Cdd:TIGR02168  712 ---EELEQLRKELEELSRQISALRKDLARL--EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1953050669 2980 --QLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRRGVCSME 3030
Cdd:TIGR02168  787 leAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1433-1731 6.67e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 6.67e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1433 QAVEREHEREEFQREIQRLEEQLRQAARPRPhgpRVSDE-EQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEE 1511
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKALA---ELRKElEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1512 EIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKqmsnlllVSTLQSKLDEGRcpvppadscpegpeVQLE 1591
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-------IEQLKEELKALR--------------EALD 806

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1592 AVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEvlhlNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQL 1671
Cdd:TIGR02168  807 ELRAELTLLNEEAANLRERLESLERRIAATERR----LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNER 882

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1672 EAQLAGMGSgalrevtydRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQE 1731
Cdd:TIGR02168  883 ASLEEALAL---------LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2427-2892 7.04e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 7.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2427 LDWRGEFLQAVQEAFGKEREMLRAELQprpcgsapgEHSSLLERLEKVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRm 2506
Cdd:COG1196    321 LEEELAELEEELEELEEELEELEEELE---------EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE- 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2507 tHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLR 2586
Cdd:COG1196    391 -ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2587 SELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAAL------------QELESERGKERALQSRLEEAQLQHLQ 2654
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKaalllaglrglaGAVAVLIGVEAAYEAALEAALAAALQ 549

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2655 REG-QSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLEL 2733
Cdd:COG1196    550 NIVvEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2734 AAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRC 2813
Cdd:COG1196    630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953050669 2814 LRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELelqrqrdEHKIRQLQRTVQALEA 2892
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL-------ERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2586-2907 8.17e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.08  E-value: 8.17e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2586 RSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQ---SRLEEAQLQHLQREGQSSKT 2662
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkdlARLEAEVEQLEERIAQLSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2663 LEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQieasRCEALLAQERGQLSELQRSLEAEKGRSLElaaalrherl 2742
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE----QLKEELKALREALDELRAELTLLNEEAAN---------- 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2743 LTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQ 2822
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2823 QQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRE---------------LELQRQRDEHKIRQLQRTV 2887
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEeysltleeaealenkIEDDEEEARRRLKRLENKI 981

                          330       340
                   ....*....|....*....|....*
gi 1953050669 2888 QA-----LEAKEEAAQrpEAERLQE 2907
Cdd:TIGR02168  982 KElgpvnLAAIEEYEE--LKERYDF 1004
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1186-1518 1.20e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 1.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1186 SSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLM 1265
Cdd:TIGR02168  671 SILERRREIEE----LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1266 LELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAGT 1345
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1346 pAPIAHEDSALRREVECLtQEQSEARKQSEKDRAALLSQMKVFEAELEEQLsrheacakqaEELSALRQQMAALDKHLRS 1425
Cdd:TIGR02168  827 -ESLERRIAATERRLEDL-EEQIEELSEDIESLAAEIEELEELIEELESEL----------EALLNERASLEEALALLRS 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1426 QRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREK-SDGFNELVIKKELADR 1504
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEySLTLEEAEALENKIED 965

                          330
                   ....*....|....
gi 1953050669 1505 QVMIQEEEIRRLEE 1518
Cdd:TIGR02168  966 DEEEARRRLKRLEN 979
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2466-2809 1.72e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.93  E-value: 1.72e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2466 SLLERLEKVvQEQEKSLEHLRAS---DRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVEL 2542
Cdd:TIGR02169  671 SEPAELQRL-RERLEGLKRELSSlqsELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE-ELEEDLSS 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2543 LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLvvEQTVVRDLRSELREckqdnerLLASLGEAQKEVLQLRSVLDSKES 2622
Cdd:TIGR02169  749 LEQEIENVKSELKELEARIEELEEDLHKLEEAL--NDLEARLSHSRIPE-------IQAELSKLEEEVSRIEARLREIEQ 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2623 NLRAALQELESERGKERALQSRLEEAQLQHLQREGQ---SSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQK--- 2696
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEienLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAqlr 899

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2697 ELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELaaalrherlltEQLSRGPRESPAHHALLRKLKEEKSRAAELQA 2776
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI-----------EDPKGEDEEIPEEELSLEDVQAELQRVEEEIR 968

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 1953050669 2777 RLEQVQR---QQEADVQKRRAELEREKEVRAAQARE 2809
Cdd:TIGR02169  969 ALEPVNMlaiQEYEEVLKRLDELKEKRAKLEEERKA 1004
PTZ00121 PTZ00121
MAEBL; Provisional
 2463-2917 2.06e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 2.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2463 EHSSLLERLEKVVQEQEKSLEHLRA-SDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAE---ARGSRQEHQLRR 2538
Cdd:PTZ00121  1312 EEAKKADEAKKKAEEAKKKADAAKKkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAkkkADAAKKKAEEKK 1391

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2539 QVELLAYKVEQEKRIASDVQKTlTEEQEKASSVRKLlVVEQTVVRDLRSELRECKQDNErlLASLGEAQKEVLQLRSvlD 2618
Cdd:PTZ00121  1392 KADEAKKKAEEDKKKADELKKA-AAAKKKADEAKKK-AEEKKKADEAKKKAEEAKKADE--AKKKAEEAKKAEEAKK--K 1465

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2619 SKESNLRAALQELESERGKERALQSRLEEAQ--LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQK 2696
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKkkADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEK 1545

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2697 ELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRH-ERLLTEQLSRGPRESpahhallRKLKEEKSRAA-EL 2774
Cdd:PTZ00121  1546 KKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKaEEARIEEVMKLYEEE-------KKMKAEEAKKAeEA 1618

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2775 QARLEQVQRQQEADVQKRRAELEREKEVRAAQ---AREPGRCLRREGHASQQQAGLEPLQAGLAAQEGRKDARRA---DV 2848
Cdd:PTZ00121  1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEelkKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEAlkkEA 1698

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953050669 2849 GPGRADAEMRPTGAKEKLRELELQRQRDEHKIR--QLQRTVQALEAKEEAAQRPEAERLQEERLGLERVRQ 2917
Cdd:PTZ00121  1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKaeEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769
PTZ00121 PTZ00121
MAEBL; Provisional
 172-876 7.55e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 7.55e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  172 ELRAMLNGRHAQELALLRSRQQQElELAREQHAREQEEMR----LRCSQETAKLKEKLQSEMERNARAVESLKRDWESER 247
Cdd:PTZ00121  1150 DAKRVEIARKAEDARKAEEARKAE-DAKKAEAARKAEEVRkaeeLRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEA 1228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  248 GLCLENLRRELSAKHRSELENLQDQFkRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERCQYVQDL 327
Cdd:PTZ00121  1229 VKKAEEAKKDAEEAKKAEEERNNEEI-RKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  328 ----ELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDASARTPHGEELEQRErecgvqQQRRGR 403
Cdd:PTZ00121  1308 kkkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE------AKKKAD 1381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  404 RAEQESELGQSPEGAVERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERREQRvgpslqpelAENHRchltawtS 483
Cdd:PTZ00121  1382 AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKK---------AEEAK-------K 1445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  484 SLEAQQQAGlvETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEvvarglglEAEHRLKLLLLQTELKEEMDvl 563
Cdd:PTZ00121  1446 ADEAKKKAE--EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE--------EAKKKADEAKKAAEAKKKAD-- 1513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  564 klENRNLHEKLQHEVCLKEDLERVKHSLVEdhREELKKANErlqlVKQELKDKEAEWKVASEDlKRKAEEELTLMLHDLK 643
Cdd:PTZ00121  1514 --EAKKAEEAKKADEAKKAEEAKKADEAKK--AEEKKKADE----LKKAEELKKAEEKKKAEE-AKKAEEDKNMALRKAE 1584

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  644 EQAEAEKQSVINKFELREiKMRQLQDQQAAQildlegslvEQQGRLRQLEHGLEAEECPRCGHCGQEPAGRVAPADQdwe 723
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYE-EEKKMKAEEAKK---------AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE--- 1651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  724 laTRRLREDCALQLMQAQSRFLKERKELTEKFTAEQD------ALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRR 797
Cdd:PTZ00121  1652 --LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDekkaaeALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK 1729

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953050669  798 AEVEELKASVESERWALAEARVAELQTEHAAAISALEARHSallgslESRHLSEVQAMREEHRQALEQLRVDLEKQLQE 876
Cdd:PTZ00121  1730 IKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA------EEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 138-638 7.56e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 7.56e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  138 LELEALRLSLSNMHTAQLELTQA-NLQKEKETALTELRAMLNGRHAQELALLRSRQQQ--ELELAREQHAREQEEMRLRC 214
Cdd:COG1196    281 LELEEAQAEEYELLAELARLEQDiARLEERRRELEERLEELEEELAELEEELEELEEEleELEEELEEAEEELEEAEAEL 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  215 SQETAKLKEKLQSEMERNARAVEslkrdweserglclENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQA 294
Cdd:COG1196    361 AEAEEALLEAEAELAEAEEELEE--------------LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  295 ECALRTLEAQHEEALRQLREDLQSErcQYVQDLELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLEsPRPDR 374
Cdd:COG1196    427 EEALAELEEEEEEEEEALEEAAEEE--AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE-AEADY 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  375 QDASARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGA-VERGREDPVLLEQRLQDATEEPSLESGGIGPSSMR 453
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAlQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  454 EGERREQRVGPSLQPELAENHRCHLTAWTSSLEAQQQAGLVETQESE-GEQREGLSEGPGQELTQVpvpcaqgtaLKVDT 532
Cdd:COG1196    584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAArLEAALRRAVTLAGRLREV---------TLEGE 654

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  533 EVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQE 612
Cdd:COG1196    655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                          490       500
                   ....*....|....*....|....*.
gi 1953050669  613 LKDKEAEWKVASEDLKRKAEEELTLM 638
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPP 760
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1218-1907 1.20e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.23  E-value: 1.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1218 QLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEH 1297
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1298 GLAEELEGLRQQLQQAAQQQAELKEENSAL------WSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQSEAR 1371
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESRLEELeeqletLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELL 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1372 KQ-SEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQR 1450
Cdd:TIGR02168  428 KKlEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG 507

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1451 LEEQLRQAARPRPHGPRVSDEEQLDEEVEL-LQEKLREKSDgfNELVIKKELADRQV--MIQEEEIRR--LEETNASCRR 1525
Cdd:TIGR02168  508 VKALLKNQSGLSGILGVLSELISVDEGYEAaIEAALGGRLQ--AVVVENLNAAKKAIafLKQNELGRVtfLPLDSIKGTE 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1526 EAAQLREELERQRDAMKALQQDKEALQEKQ------MSNLLLVSTLQSKLD-------EGRCPVPPADSCPEGPEVQLEA 1592
Cdd:TIGR02168  586 IQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsylLGGVLVVDDLDNALElakklrpGYRIVTLDGDLVRPGGVITGGS 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1593 VQRA--LQQRESEVLDLKEQLGKMKDDLvsksdevlhlnLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQ 1670
Cdd:TIGR02168  666 AKTNssILERRREIEELEEKIEELEEKI-----------AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1671 LEAqlAGMGSGALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAE---EMEQLHEVIERLQEELSLgapavpaavdce 1747
Cdd:TIGR02168  735 LAR--LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKA------------ 800

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1748 lpavpapavgpEALAAAGAASRLFAEQEHRHGQALEalQQRLQAAEEAAAGQLAELERSAALREAEVQAMASQIQAFEAA 1827
Cdd:TIGR02168  801 -----------LREALDELRAELTLLNEEAANLRER--LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1828 LRAKEARLAERDLEIDAMKRQKLAHSAELETilaaFSRFRRTLERQPLAAEDeppELQRLRVQCVRLSRQLQVLNQRFLR 1907
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEE----LSEELRELESKRSELRR---ELEELREKLAQLELRLEGLEVRIDN 940
PTZ00121 PTZ00121
MAEBL; Provisional
 2416-2916 1.36e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 1.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2416 QKGEQEPPDPGLDWRGEFLQAVQEAFGKEREMLRAELQPRPCGSAPGEHSSLLERLEKVvqEQEKSLEHLRASDRSSLLS 2495
Cdd:PTZ00121  1096 AFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRV--EIARKAEDARKAEEARKAE 1173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2496 EIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEhqlRRQVEllAYKVEQEKRI-----ASDVQKTlTEEQEKASS 2570
Cdd:PTZ00121  1174 DAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEE---RKAEE--ARKAEDAKKAeavkkAEEAKKD-AEEAKKAEE 1247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2571 VRKLLVVEQTVVRDLRSELR--------------ECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRA--ALQELESE 2634
Cdd:PTZ00121  1248 ERNNEEIRKFEEARMAHFARrqaaikaeearkadELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEA 1327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2635 RGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEAllaQERG 2714
Cdd:PTZ00121  1328 KKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKA---EEDK 1404

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2715 QLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHAllRKLKEEKSRAAELQARLEQVQRQQEADVQKRRA 2794
Cdd:PTZ00121  1405 KKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA--KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEA 1482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2795 ELEREKEVRAAQAREPGRCLRREGHASQQQAGLEPLQAGLAAQEGRK--DARRADvgpgradaEMRPTGAKEKLRELelq 2872
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaeEAKKAD--------EAKKAEEKKKADEL--- 1551

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1953050669 2873 rqRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERLGLERVR 2916
Cdd:PTZ00121  1552 --KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1421-1733 1.59e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 1.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1421 KHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAAR-----PRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNEL 1495
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKeleelSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1496 VIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRCP 1575
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1576 VppadscpEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSR---AAVSVRELQEENAS 1652
Cdd:TIGR02168  840 L-------EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEleeLSEELRELESKRSE 912

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1653 LKAFLQNKEKEImcvsEQLEAQLAGMGSgalrevtydrsseieELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEE 1732
Cdd:TIGR02168  913 LRRELEELREKL----AQLELRLEGLEV---------------RIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRR 973


                   .
gi 1953050669 1733 L 1733
Cdd:TIGR02168  974 L 974
PTZ00121 PTZ00121
MAEBL; Provisional
 1217-1888 1.62e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.93  E-value: 1.62e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1217 RQLEEARQIHSRFEKEFSCKNEET--AQVVRKQQQL-----LERLEE----ENAARTRLMLELHQAQGIIEGFKEEKASL 1285
Cdd:PTZ00121  1158 RKAEDARKAEEARKAEDAKKAEAArkAEEVRKAEELrkaedARKAEAarkaEEERKAEEARKAEDAKKAEAVKKAEEAKK 1237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1286 QEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENsalwSQKEASAAEAEAREAGTPAPIAHEdsalRREVECLTQ 1365
Cdd:PTZ00121  1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE----ARKADELKKAEEKKKADEAKKAEE----KKKADEAKK 1309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1366 EQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQfmDEQAVEREHEREEFQ 1445
Cdd:PTZ00121  1310 KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK--KEEAKKKADAAKKKA 1387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1446 REIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKSDGfNELVIKKELADR--QVMIQEEEIRRLEETN--A 1521
Cdd:PTZ00121  1388 EEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA-DEAKKKAEEAKKadEAKKKAEEAKKAEEAKkkA 1466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1522 SCRREAAQLREELERQRDAMKALQQDKEAlqEKQMSNLLLVSTLQSKLDEGRcpvppadscpegpevQLEAVQRALQQRE 1601
Cdd:PTZ00121  1467 EEAKKADEAKKKAEEAKKADEAKKKAEEA--KKKADEAKKAAEAKKKADEAK---------------KAEEAKKADEAKK 1529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1602 SEVLDLKEQLGKMKDdlVSKSDEVlhlnleLDAQSSRAAVSVRELQE-ENASLKAFLQNKEKEIMCVSEQLEAQLAGMGS 1680
Cdd:PTZ00121  1530 AEEAKKADEAKKAEE--KKKADEL------KKAEELKKAEEKKKAEEaKKAEEDKNMALRKAEEAKKAEEARIEEVMKLY 1601

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1681 GALREVTYDRSSEIEELRSIIENLRenqqrlqkeKAEEMEQLHEVIERLQEELSLGAPAVPAAVDCELPAVPAPAVGPEA 1760
Cdd:PTZ00121  1602 EEEKKMKAEEAKKAEEAKIKAEELK---------KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE 1672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1761 LAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQamaSQIQAFEAALRAKEARLAERDL 1840
Cdd:PTZ00121  1673 DKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEE---NKIKAEEAKKEAEEDKKKAEEA 1749

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*....
gi 1953050669 1841 EIDAMKRQKLAHSAELETILAAFSRF-RRTLERQPLAAEDEPPELQRLR 1888
Cdd:PTZ00121  1750 KKDEEEKKKIAHLKKEEEKKAEEIRKeKEAVIEEELDEEDEKRRMEVDK 1798
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1199-1603 2.66e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 2.66e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1199 QSLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGF 1278
Cdd:COG1196    354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1279 KEEKASLQEALCRQETAEHGLAEELEGL--------RQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAGTPAPIA 1350
Cdd:COG1196    434 EEEEEEEEEALEEAAEEEAELEEEEEALlellaellEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1351 HEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEE-------LSALRQQMAALDKHL 1423
Cdd:COG1196    514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratflpLDKIRARAALAAALA 593

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1424 RSQRQF-MDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELA 1502
Cdd:COG1196    594 RGAIGAaVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAA 673

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1503 DRQVM-IQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRCPVPPADS 1581
Cdd:COG1196    674 LLEAEaELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL 753

                          410       420
                   ....*....|....*....|..
gi 1953050669 1582 CPEGPEVQLEAVQRALQQRESE 1603
Cdd:COG1196    754 EELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1211-1553 3.64e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.70  E-value: 3.64e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1211 LALDSTRQLEEARQIHSR---FEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQE 1287
Cdd:TIGR02169  665 GILFSRSEPAELQRLRERlegLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEE 744

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1288 ALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSAL--------WSQKEASAAEAEAREAGTPAPIAHEDSALRRE 1359
Cdd:TIGR02169  745 DLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlshsrIPEIQAELSKLEEEVSRIEARLREIEQKLNRL 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1360 VECLTQEQSEaRKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREH 1439
Cdd:TIGR02169  825 TLEKEYLEKE-IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1440 EREEFQREIQRLEEQLRQAArprphgprVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMiqEEEIRRLEET 1519
Cdd:TIGR02169  904 KIEELEAQIEKKRKRLSELK--------AKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRV--EEEIRALEPV 973

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 1953050669 1520 NAScrreAAQLREELERQRDAMKA----LQQDKEALQE 1553
Cdd:TIGR02169  974 NML----AIQEYEEVLKRLDELKEkrakLEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2474-2799 5.20e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 5.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2474 VVQEQEKSLEHLRAsDRSSLLSEIQALRAQLRMTHLQNQEKLQQLcAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRI 2553
Cdd:TIGR02168  671 SILERRREIEELEE-KIEELEEKIAELEKALAELRKELEELEEEL-EQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2554 ASDVQKTLTEEQEKASSVRKLLvveqtvvRDLRSELRECKQDNERLLASLGEAQKEVLQLRSvldskesnlraALQELES 2633
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERL-------EEAEEELAEAEAEIEELEAQIEQLKEELKALRE-----------ALDELRA 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2634 ERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQI---EASRCEALLA 2710
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAllnERASLEEALA 890

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2711 QERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPREspahhaLLRKLKEEKSRAAELQARLEQVQRQQEADVQ 2790
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG------LEVRIDNLQERLSEEYSLTLEEAEALENKIE 964


                   ....*....
gi 1953050669 2791 KRRAELERE 2799
Cdd:TIGR02168  965 DDEEEARRR 973
PTZ00121 PTZ00121
MAEBL; Provisional
 165-700 6.42e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.00  E-value: 6.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  165 EKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAVESLKRDWE 244
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  245 SERGLCL---ENLRRELSAKHRSELENLQDQFKRELSEQKAELEkifQAKNQAECALRTLEAQHEEALRQLREDLQSERC 321
Cdd:PTZ00121  1289 KKKADEAkkaEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAD---AAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK 1365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  322 QYVQDL---ELRLRDQEVEKQLElESLRASYAELKAqsqEEIRRLWSQLESPRPDRQDASARTPHGEELEQ-RERECGVQ 397
Cdd:PTZ00121  1366 AEAAEKkkeEAKKKADAAKKKAE-EKKKADEAKKKA---EEDKKKADELKKAAAAKKKADEAKKKAEEKKKaDEAKKKAE 1441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  398 QQRRGRRAEQESELGQSPEGAVERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGErrEQRVGPSLQPELAENHRCH 477
Cdd:PTZ00121  1442 EAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKAD--EAKKAAEAKKKADEAKKAE 1519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  478 LTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEVV-----ARGLGLEAEHRLKLLLL 552
Cdd:PTZ00121  1520 EAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNmalrkAEEAKKAEEARIEEVMK 1599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  553 QTELKEEMDVLKL----ENRNLHEKLQHEVCLKEDLERVKHSLVEDHR--EELKKANERLQLVKQELKDKEAEWKVASED 626
Cdd:PTZ00121  1600 LYEEEKKMKAEEAkkaeEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKkaEELKKAEEENKIKAAEEAKKAEEDKKKAEE 1679

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953050669  627 LKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREI-KMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEE 700
Cdd:PTZ00121  1680 AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKkKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEE 1754
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1364-1733 7.77e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.54  E-value: 7.77e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1364 TQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFM---DEQAVEREHE 1440
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKrklEEKIRELEER 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1441 REEFQREIQRLEEQLRqaarprphgpRVSDEEQLDEEVELLQEKLREKSDGFNElvIKKELADRQVMIQ--EEEIRRLEE 1518
Cdd:PRK03918   268 IEELKKEIEELEEKVK----------ELKELKEKAEEYIKLSEFYEEYLDELRE--IEKRLSRLEEEINgiEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1519 TNascrREAAQLREELERQRDAMKALQQDKEALQEkqmsnlllVSTLQSKLDEGRCPVppADSCPEGPEVQLEAVQRALQ 1598
Cdd:PRK03918   336 KE----ERLEELKKKLKELEKRLEELEERHELYEE--------AKAKKEELERLKKRL--TGLTPEKLEKELEELEKAKE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1599 QRESEVLDLKEQLGKMKDDLVSKSDEVlhlnLELDAQSSRAAVSVRELQEEN-----ASLKAFLQNKEKEIMCVSEQLEA 1673
Cdd:PRK03918   402 EIEEEISKITARIGELKKEIKELKKAI----EELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKELKEIEEKERK 477

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1953050669 1674 QLAgmgsgALREV--TYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEEL 1733
Cdd:PRK03918   478 LRK-----ELRELekVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKL 534
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1363-1722 1.98e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 57.08  E-value: 1.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1363 LTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALD---KHLRSQRQFMD--EQAVER 1437
Cdd:COG4717     51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEaelEELREELEKLEklLQLLPL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1438 EHEREEFQREIQRLEEQLRQAARprphgpRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQ-EEEIRRL 1516
Cdd:COG4717    131 YQELEALEAELAELPERLEELEE------RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDlAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1517 EETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQ-----------MSNLLLVSTLQSKLDEGRCPVPPA------ 1579
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlkearlllliAAALLALLGLGGSLLSLILTIAGVlflvlg 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1580 --------------DSCPEGPEVQLEAVQRALQQRE----------------SEVLDLKEQLGKMKDDLVSKSD-----E 1624
Cdd:COG4717    285 llallflllarekaSLGKEAEELQALPALEELEEEEleellaalglppdlspEELLELLDRIEELQELLREAEEleeelQ 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1625 VLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSGALREVTYDRSSEIEELRSIIENL 1704
Cdd:COG4717    365 LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEEL 444

                          410       420
                   ....*....|....*....|.
gi 1953050669 1705 RENQQRLQKEKAE---EMEQL 1722
Cdd:COG4717    445 EEELEELREELAEleaELEQL 465
PTZ00121 PTZ00121
MAEBL; Provisional
 2535-2918 2.00e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 2.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2535 QLRRQVELLAYkvEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRdlRSELRECKQDNERLLASLGEAQKEVLQLR 2614
Cdd:PTZ00121  1083 AKEDNRADEAT--EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARK--AEEARKAEDARKAEEARKAEDAKRVEIAR 1158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2615 SVLDSKESNLRAALQELESERGKERALQSR-LEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDN 2693
Cdd:PTZ00121  1159 KAEDARKAEEARKAEDAKKAEAARKAEEVRkAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKD 1238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2694 LQKELQIEASRC-EALLAQERGQLSELQRSLEAEKGRSLELAAALR--HERLLTEQLSRGPRESPAHHAllRKLKEEKSR 2770
Cdd:PTZ00121  1239 AEEAKKAEEERNnEEIRKFEEARMAHFARRQAAIKAEEARKADELKkaEEKKKADEAKKAEEKKKADEA--KKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2771 AAELQARLEQVQRQqeADVQKRRAElEREKEVRAAQAREPGRCLRREGHASQQQAG-LEPLQAGLAAQEGRKDA---RRA 2846
Cdd:PTZ00121  1317 ADEAKKKAEEAKKK--ADAAKKKAE-EAKKAAEAAKAEAEAAADEAEAAEEKAEAAeKKKEEAKKKADAAKKKAeekKKA 1393

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953050669 2847 DVGPGRADAEMRPTgakEKLRELELQRQRDEHKIRQLQRTVQALEAK---EEAAQRPEAERLQEERLGLERVRQQ 2918
Cdd:PTZ00121  1394 DEAKKKAEEDKKKA---DELKKAAAAKKKADEAKKKAEEKKKADEAKkkaEEAKKADEAKKKAEEAKKAEEAKKK 1465
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1238-1553 2.14e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.00  E-value: 2.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1238 EETAQVVRKQQQLLERLEEENAARTR---LMLELHQAQGII-----EGFKEEKASLQEALCRQETAEHGLAEELEGLRQQ 1309
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKAERyqaLLKEKREYEGYEllkekEALERQKEAIERQLASLEEELEKLTEEISELEKR 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1310 LQQAAQQQAELKEENSALWSQKEASAAEAEAREAGtpapiahEDSALRREVECLTQEQSEA---RKQSEKDRAALLSQMK 1386
Cdd:TIGR02169  267 LEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEA-------EIASLERSIAEKERELEDAeerLAKLEAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1387 VFEAELEEQLSRHEAC----AKQAEELSALRQQMAALDKHLRSQRQFMDEQAVERE---HEREEFQREIQRLEEQLRQA- 1458
Cdd:TIGR02169  340 ELEREIEEERKRRDKLteeyAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEklkREINELKRELDRLQEELQRLs 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1459 ---ARPRPHGPRVSDE-EQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREAAqlreEL 1534
Cdd:TIGR02169  420 eelADLNAAIAGIEAKiNELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELA----EA 495

                          330
                   ....*....|....*....
gi 1953050669 1535 ERQRDAMKALQQDKEALQE 1553
Cdd:TIGR02169  496 EAQARASEERVRGGRAVEE 514
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 580-1063 2.25e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 2.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  580 LKEDLERVKHSLVEDhREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLmlhdlkEQAEAEKQSVINKFEL 659
Cdd:COG1196    314 LEERLEELEEELAEL-EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA------EAELAEAEEELEELAE 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  660 REIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcGQEPAGRVAPADQDWELATRRLREDCALQLMQ 739
Cdd:COG1196    387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE-------EALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  740 AQSRFLKERKELTEKFTAEQDALLQEAQEKHAcdmrllqerhqqhVLSLTAQLEARRRAEVEELKASVESERWALAEARV 819
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAA-------------RLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  820 AELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQlRVDLEKQLQEKEASHPTPLTQALEKHPLSHGQE 899
Cdd:COG1196    527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG-RATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  900 LPPVEGGLRTQTSSGQLEGVKAPVPP----------------EVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQLHC 963
Cdd:COG1196    606 SDLREADARYYVLGDTLLGRTLVAARleaalrravtlagrlrEVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  964 QEEPEVLEcpsepFLEQQILQpkgefESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQILSLS 1043
Cdd:COG1196    686 ERLAEEEL-----ELEEALLA-----EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

                          490       500
                   ....*....|....*....|
gi 1953050669 1044 HEVEERRRDLEQLQQRRERE 1063
Cdd:COG1196    756 LPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1403-1734 2.33e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.00  E-value: 2.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1403 AKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREH--EREEFQREIQRLEEQLRQAARPRPHGPRVSDEEQLD---EE 1477
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKaeRYQALLKEKREYEGYELLKEKEALERQKEAIERQLAsleEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1478 VELLQEKLREKSDGFNELVIKKELADRQVM-IQEEEIRRLeetnascRREAAQLREELERQRDAMKALQQDKEALQEKQM 1556
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEQLLEELNKKIKdLGEEEQLRV-------KEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1557 SNLLLVSTLQSKLdegrcpvppadscpEGPEVQLEAVQRALQQRESEVLDLKEQLgkmkDDLVSKSDEVLHLNLELDAQS 1636
Cdd:TIGR02169  326 KLEAEIDKLLAEI--------------EELEREIEEERKRRDKLTEEYAELKEEL----EDLRAELEEVDKEFAETRDEL 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1637 SRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQ---LEAQLAGMgSGALREVTYDRSSEIEELRSIIENLRENQQRLQK 1713
Cdd:TIGR02169  388 KDYREKLEKLKREINELKRELDRLQEELQRLSEEladLNAAIAGI-EAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          330       340
                   ....*....|....*....|.
gi 1953050669 1714 EKaEEMEQLHEVIERLQEELS 1734
Cdd:TIGR02169  467 YE-QELYDLKEEYDRVEKELS 486
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 251-872 5.33e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 5.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  251 LENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERcqyvqdlELR 330
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY-------ELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  331 LRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDASArtphgEELEQRERECGVQQQRRGRRAEQESE 410
Cdd:COG1196    295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELE-----EELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  411 LGQSPEGAVERGREDPVLLEQRLQDATEEPSLEsggigpssmREGERREQRvgpslqpelAENHRCHLTAWTSSLEAQQQ 490
Cdd:COG1196    370 AEAELAEAEEELEELAEELLEALRAAAELAAQL---------EELEEAEEA---------LLERLERLEEELEELEEALA 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  491 AGLVETQESEGEQREglsegpgqeltqvpvpcAQGTALKVDTEVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNL 570
Cdd:COG1196    432 ELEEEEEEEEEALEE-----------------AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  571 heklqhevcLKEDLERVKHSLVEDHREELKKANERL--QLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEA 648
Cdd:COG1196    495 ---------LLLEAEADYEGFLEGVKAALLLAGLRGlaGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  649 EKQSVINKFE-LREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcGQEPAGRVAPADQDWELATR 727
Cdd:COG1196    566 LKAAKAGRATfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVL-------GDTLLGRTLVAARLEAALRR 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  728 RLREDCALQLMQAQSRFLKERKELTEKFTAEQDALLQEAQEKhacdMRLLQERHQQHVLSLTAQLEARRRAEVEELKASV 807
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE----LEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953050669  808 ESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAmREEHRQALEQLRVDLEK 872
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD-LEELERELERLEREIEA 778
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1236-1731 6.16e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 6.16e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1236 KNEETAQVVRKQQQLLERLEEENA-ARTRLMLELHQAQGI---IEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQ 1311
Cdd:PRK02224   273 EREELAEEVRDLRERLEELEEERDdLLAEAGLDDADAEAVearREELEDRDEELRDRLEECRVAAQAHNEEAESLREDAD 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1312 QAAQQQAELKEENSALWSqkeasaaeaeareagtpapiahEDSALRREVECLTQEQSEARKQSEKDRAALLSQmkvfEAE 1391
Cdd:PRK02224   353 DLEERAEELREEAAELES----------------------ELEEAREAVEDRREEIEELEEEIEELRERFGDA----PVD 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1392 LEEQLSRHEACakqAEELSALRQQMAALDKHLRSQRQFMDE--------------QAVERE---HEREEFQREIQRLEEQ 1454
Cdd:PRK02224   407 LGNAEDFLEEL---REERDELREREAELEATLRTARERVEEaealleagkcpecgQPVEGSphvETIEEDRERVEELEAE 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1455 LRQAArprphgprvSDEEQLDEEVELLqEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREEL 1534
Cdd:PRK02224   484 LEDLE---------EEVEEVEERLERA-EDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEA 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1535 ERQRDAMKALQQDKEALQEKqmsnlllVSTLQSKLDEGRCPVPPADSCPEGPEvQLEAVQRALQQRESEVLDLKEQLGKM 1614
Cdd:PRK02224   554 EEKREAAAEAEEEAEEAREE-------VAELNSKLAELKERIESLERIRTLLA-AIADAEDEIERLREKREALAELNDER 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1615 KDDLVSKSDEVLHLNLELDAQssraavSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSgalrevtydRSSEI 1694
Cdd:PRK02224   626 RERLAEKRERKRELEAEFDEA------RIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGA---------VENEL 690

                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 1953050669 1695 EELrsiiENLRENQQRLQkEKAEEMEQLHEVIERLQE 1731
Cdd:PRK02224   691 EEL----EELRERREALE-NRVEALEALYDEAEELES 722
PTZ00121 PTZ00121
MAEBL; Provisional
 1213-1733 9.67e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.15  E-value: 9.67e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1213 LDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENA-----ARTRLMLELHQAQGIIEGFK-EEKASLQ 1286
Cdd:PTZ00121  1214 AEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEArmahfARRQAAIKAEEARKADELKKaEEKKKAD 1293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1287 EALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALwSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQE 1366
Cdd:PTZ00121  1294 EAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAA-KKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK 1372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1367 QSEARKQSEKDRAALLSQMKVFEAELE--------EQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVERE 1438
Cdd:PTZ00121  1373 KEEAKKKADAAKKKAEEKKKADEAKKKaeedkkkaDELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKK 1452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1439 HEREEFQREIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEE 1518
Cdd:PTZ00121  1453 AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEE 1532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1519 T-------NASCRREAAQLR--EELERQRDAMKALQQDKEalqEKQMSNLLLVSTLQSKLDEGRCPvppadscPEGPEVQ 1589
Cdd:PTZ00121  1533 AkkadeakKAEEKKKADELKkaEELKKAEEKKKAEEAKKA---EEDKNMALRKAEEAKKAEEARIE-------EVMKLYE 1602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1590 LEAVQRALQQResevldlKEQLGKMKDDLVSKSDEVLHLNLEL---DAQSSRAAVSVRELQEENASLKAFLQNKEKEimc 1666
Cdd:PTZ00121  1603 EEKKMKAEEAK-------KAEEAKIKAEELKKAEEEKKKVEQLkkkEAEEKKKAEELKKAEEENKIKAAEEAKKAEE--- 1672

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953050669 1667 vsEQLEAQLAGMGSGALREVTYDRSSEIEELRSiIENLRENQQRlQKEKAEEMEQLHEVIERLQEEL 1733
Cdd:PTZ00121  1673 --DKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-AEELKKKEAE-EKKKAEELKKAEEENKIKAEEA 1735
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1267-1554 1.13e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.68  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1267 ELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEAsaaeaeareagtp 1346
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ------------- 744

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1347 apIAHEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEaELEEQLSRH-EACAKQAEELSALRQQMAALDKHLRS 1425
Cdd:TIGR02168  745 --LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE-ELEAQIEQLkEELKALREALDELRAELTLLNEEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1426 QRQfmDEQAVEREHEREEfqREIQRLEEQLRQAArprphgprvSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQ 1505
Cdd:TIGR02168  822 LRE--RLESLERRIAATE--RRLEDLEEQIEELS---------EDIESLAAEIEELEELIEELESELEALLNERASLEEA 888

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1953050669 1506 VM-------IQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEK 1554
Cdd:TIGR02168  889 LAllrseleELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1351-1564 1.13e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 54.74  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1351 HEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEE-QLSRHEACAKQAEELSALRQQMAALDKHLRSQRQF 1429
Cdd:pfam17380  339 QERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERlQMERQQKNERVRQELEAARKVKILEEERQRKIQQQ 418

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1430 MDEQAVEREHEREEFQREIQRLEEQ-------LRQAARPRPHGP---RVSDEEQLDEEVELLQEKL-REKSDGFNELVIK 1498
Cdd:pfam17380  419 KVEMEQIRAEQEEARQREVRRLEEEraremerVRLEEQERQQQVerlRQQEEERKRKKLELEKEKRdRKRAEEQRRKILE 498

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953050669 1499 KEL-ADRQVMIQEEEIRRLEETNASCRREAAQlreELERQRDAMKALQQDKEALQEKQMSNLLLVST 1564
Cdd:pfam17380  499 KELeERKQAMIEEERKRKLLEKEMEERQKAIY---EEERRREAEEERRKQQEMEERRRIQEQMRKAT 562
PTZ00121 PTZ00121
MAEBL; Provisional
 245-1080 1.14e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.76  E-value: 1.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  245 SERGLCLENLRRELSAKHRS-ELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERCQY 323
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNrADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  324 VQDLELRLRDQEVEKQLELESLR----ASYAElKAQSQEEIRRlwsqlesprpdrqdasartphGEELEQRERecgVQQQ 399
Cdd:PTZ00121  1148 AEDAKRVEIARKAEDARKAEEARkaedAKKAE-AARKAEEVRK---------------------AEELRKAED---ARKA 1202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  400 RRGRRAEQESELGQSPEGAVERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERREQRVGPSLQPELAENHRchlt 479
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEAR---- 1278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  480 AWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEVVARglGLEAEHRLKLLLLQTELKEE 559
Cdd:PTZ00121  1279 KADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKK--KAEEAKKAAEAAKAEAEAAA 1356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  560 MDVLKLENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVAsEDLKRKAEEELTlmL 639
Cdd:PTZ00121  1357 DEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA-DEAKKKAEEKKK--A 1433

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  640 HDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEECPRcghcGQEPAGRVAPAD 719
Cdd:PTZ00121  1434 DEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKK----KADEAKKAAEAK 1509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  720 QDWELATRRLREDCALQLMQA-QSRFLKERKELTEKFTAEQ---DALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEAR 795
Cdd:PTZ00121  1510 KKADEAKKAEEAKKADEAKKAeEAKKADEAKKAEEKKKADElkkAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA 1589

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  796 RRAEVEELKASVESERWALAEarvaELQTEHAAAISALEARHSallgSLESRHLSEVQAMREEHRQALEQLRVDLEKQL- 874
Cdd:PTZ00121  1590 EEARIEEVMKLYEEEKKMKAE----EAKKAEEAKIKAEELKKA----EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKi 1661

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  875 -QEKEASHPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQ-----EGAPVPAEvEAQRPA- 947
Cdd:PTZ00121  1662 kAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEElkkaeEENKIKAE-EAKKEAe 1740

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  948 ----LLAELRQETGK----QQLHCQEEPEVLECPSEpflEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKE 1019
Cdd:PTZ00121  1741 edkkKAEEAKKDEEEkkkiAHLKKEEEKKAEEIRKE---KEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEG 1817

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953050669 1020 SLFLQlQEKNNQILQLKEQILSlSHEVEERRRDLEQLQQRRERENQEGTNLISMLKSDADL 1080
Cdd:PTZ00121  1818 NLVIN-DSKEMEDSAIKEVADS-KNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDL 1876
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 156-441 1.25e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 54.36  E-value: 1.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  156 ELTQANLQKEKETALTEL--RAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNA 233
Cdd:pfam17380  295 KMEQERLRQEKEEKAREVerRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEI 374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  234 RAVESLKRdWESERGLCLENLRRELSAKHRSELenLQDQFKRELSEQKAELEKI-FQAKNQAECALRTLEAQHEEALRQL 312
Cdd:pfam17380  375 SRMRELER-LQMERQQKNERVRQELEAARKVKI--LEEERQRKIQQQKVEMEQIrAEQEEARQREVRRLEEERAREMERV 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  313 REDLQsERCQYVQdlelRLRDQEVE---KQLELESLRasyaELKAQSQEEIRRLWSQLESPRPDRQDASARTPHGEELEQ 389
Cdd:pfam17380  452 RLEEQ-ERQQQVE----RLRQQEEErkrKKLELEKEK----RDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEM 522

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1953050669  390 RERECGVQQQRRGRRAEQESELGQSPEgavERGRedpvlLEQRLQDATEEPS 441
Cdd:pfam17380  523 EERQKAIYEEERRREAEEERRKQQEME---ERRR-----IQEQMRKATEERS 566
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1367-1553 3.25e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 3.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1367 QSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEEL----SALRQQMAALDKHLRSQRQFMDEQAVEREHERE 1442
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALerriAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1443 EFQREIQRLEEQLRQAARPRPHGP---RVSDE----------------EQLDEEVELLQEKLREKSDGFNELVIKKELAD 1503
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPlalLLSPEdfldavrrlqylkylaPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1504 RQVMIQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQE 1553
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1365-1732 3.39e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 3.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1365 QEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELS----ALRQQMAALDKHLRSQRQFMDEQAVEREHE 1440
Cdd:TIGR02169  677 QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEkeieQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1441 REEFQREIQRLEEQLRQAARPRphgprvsdEEQLDEEVELLQEKLREKSDGFNELvikkeladrqvmiqEEEIRRLEETN 1520
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLE--------EALNDLEARLSHSRIPEIQAELSKL--------------EEEVSRIEARL 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1521 ASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEgrcpvppadscpegPEVQLEAVQRALQQR 1600
Cdd:TIGR02169  815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE--------------LEEELEELEAALRDL 880

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1601 ESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAA---VSVRELQEENASLKAFLQNKEKEIMCVS--EQLEAQL 1675
Cdd:TIGR02169  881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSelkAKLEALEEELSEIEDPKGEDEEIPEEELslEDVQAEL 960

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1953050669 1676 AGMGSG--ALREVTYDRSSEIEELRSIIENLRENQQRLQKEKaeemEQLHEVIERLQEE 1732
Cdd:TIGR02169  961 QRVEEEirALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEER----KAILERIEEYEKK 1015
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2463-2917 3.94e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 3.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2463 EHSSLLERLEKVVQEQEKsLEHLRASDRSSLL-SEIQALRAQLRmthlQNQEKLQQLCAALTSAEARGSRQEHQLR---- 2537
Cdd:COG4913    263 RYAAARERLAELEYLRAA-LRLWFAQRRLELLeAELEELRAELA----RLEAELERLEARLDALREELDELEAQIRgngg 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2538 RQVELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELREckqdnerLLASLGEAQKEVLQLRSVL 2617
Cdd:COG4913    338 DRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA-------LLEALEEELEALEEALAEA 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2618 DSKESNLRAALQELESERGKERALQSRLEEAQLQHLQR-EGQSSKTLEEL----------------RASLEK---QFAQS 2677
Cdd:COG4913    411 EAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAlAEALGLDEAELpfvgelievrpeeerwRGAIERvlgGFALT 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2678 sqLCVALKHEQTAK---DNLQKELQIEASRCEALLAQERGQ--------------LSELQRSLEAEKGRSLELA-----A 2735
Cdd:COG4913    491 --LLVPPEHYAAALrwvNRLHLRGRLVYERVRTGLPDPERPrldpdslagkldfkPHPFRAWLEAELGRRFDYVcvdspE 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2736 AL-RHERLLTEQ-LSRGPRESPAH--------------------HALLRKLKEEKSRAAELQARLEQVQRQQEAdVQKRR 2793
Cdd:COG4913    569 ELrRHPRAITRAgQVKGNGTRHEKddrrrirsryvlgfdnraklAALEAELAELEEELAEAEERLEALEAELDA-LQERR 647

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2794 AELEREKEVRAAQAREPGrcLRREGHASQQQ-AGLEPLQAGLAAQEGRKDARRADvgpgRADAEMRPTGAKEKLRELELQ 2872
Cdd:COG4913    648 EALQRLAEYSWDEIDVAS--AEREIAELEAElERLDASSDDLAALEEQLEELEAE----LEELEEELDELKGEIGRLEKE 721

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 1953050669 2873 RQRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERLGLERVRQ 2917
Cdd:COG4913    722 LEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERE 766
PTZ00121 PTZ00121
MAEBL; Provisional
 1346-1855 7.56e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 7.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1346 PAPIAHEDSALRREVEclTQEQSEARKQSEKDRaallsqmKVFEAELEEQLSRHEAcAKQAEELSALRQQMAALD-KHLR 1424
Cdd:PTZ00121  1074 PSYKDFDFDAKEDNRA--DEATEEAFGKAEEAK-------KTETGKAEEARKAEEA-KKKAEDARKAEEARKAEDaRKAE 1143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1425 SQRQFMDEQAVEREHEREEFQR--EIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELA 1502
Cdd:PTZ00121  1144 EARKAEDAKRVEIARKAEDARKaeEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDA 1223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1503 DRQvmiqeEEIRRLEETNascRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLllvstlqsKLDEGRcpvpPADSC 1582
Cdd:PTZ00121  1224 KKA-----EAVKKAEEAK---KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAI--------KAEEAR----KADEL 1283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1583 PEGPEV-QLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELD--AQSSRAAVSVRELQEENASLKAFLQN 1659
Cdd:PTZ00121  1284 KKAEEKkKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKkkAEEAKKAAEAAKAEAEAAADEAEAAE 1363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1660 KEKEimcvSEQLEAQLAGMGSGALREVTyDRSSEIEELRSIIENLRENQQRLQKEKAEE--MEQLHEVIERLQEELSLGA 1737
Cdd:PTZ00121  1364 EKAE----AAEKKKEEAKKKADAAKKKA-EEKKKADEAKKKAEEDKKKADELKKAAAAKkkADEAKKKAEEKKKADEAKK 1438

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1738 PAVPAAVDCELPAVPAPAVGPEALAAAGAASRLFAE-----QEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREA 1812
Cdd:PTZ00121  1439 KAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEakkkaEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 1953050669 1813 EVQAMASQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAE 1855
Cdd:PTZ00121  1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAE 1561
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2583-2904 1.25e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2583 RDLRSELRECKQdnERLLASLGEAQKEVLQLRSVLDSKESNLrAALQELESERGKE-RALQSRLEEAQLQHLQREGQSSK 2661
Cdd:TIGR02169  214 QALLKEKREYEG--YELLKEKEALERQKEAIERQLASLEEEL-EKLTEEISELEKRlEEIEQLLEELNKKIKDLGEEEQL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2662 TLEELRASLEKQFAQssqlcvaLKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHER 2741
Cdd:TIGR02169  291 RVKEKIGELEAEIAS-------LERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2742 LLTEQL-SRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQARepgrclrREGHA 2820
Cdd:TIGR02169  364 EELEDLrAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAG-------IEAKI 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2821 SQQQAGLEPLQAGLAAQEGRKDARRADVGPgradaemrptgAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRP 2900
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSK-----------YEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505


                   ....
gi 1953050669 2901 EAER 2904
Cdd:TIGR02169  506 VRGG 509
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1142-1719 1.30e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 51.26  E-value: 1.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1142 LEETWPGSEAALLELDRSLPECVEMPSEAEISSHIC----ESFFMSPESSLEYE---QPIRRIYQSLGLAVEGLLeLALD 1214
Cdd:pfam05483  122 IQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCnllkETCARSAEKTKKYEyerEETRQVYMDLNNNIEKMI-LAFE 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1215 STR-QLEEAR-----QIHSRFEKEFSCKNEETAQVVRKQQQ----LLERLEEENAARTrLMLELHQAQGIIEGFKEEKAS 1284
Cdd:pfam05483  201 ELRvQAENARlemhfKLKEDHEKIQHLEEEYKKEINDKEKQvsllLIQITEKENKMKD-LTFLLEESRDKANQLEEKTKL 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1285 LQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEE-NSALWSQKEASAAEAEAREAGTPAPIAHedSALRREVECL 1363
Cdd:pfam05483  280 QDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDlQIATKTICQLTEEKEAQMEELNKAKAAH--SFVVTEFEAT 357

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1364 TQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAK----QAEELSALRQQMAALDKHLRSQRQFmDEQAVEREH 1439
Cdd:pfam05483  358 TCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKfknnKEVELEELKKILAEDEKLLDEKKQF-EKIAEELKG 436

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1440 EREEF-------QREIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQ----------------EKLREKSDGFNELv 1496
Cdd:pfam05483  437 KEQELifllqarEKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKnieltahcdklllenkELTQEASDMTLEL- 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1497 iKKELADRQVMIQEEE-----IRRLEETNASCRREAAQLREELERQRDAMKAlQQDKEALQEKQMSNLLLVSTLQSKLDE 1571
Cdd:pfam05483  516 -KKHQEDIINCKKQEErmlkqIENLEEKEMNLRDELESVREEFIQKGDEVKC-KLDKSEENARSIEYEVLKKEKQMKILE 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1572 GRCpvppadscpEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSV----RELQ 1647
Cdd:pfam05483  594 NKC---------NNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIdnyqKEIE 664

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1953050669 1648 EENASLKAFLQNKEKEIMCVSEQLEAQlagmgsgalREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEM 1719
Cdd:pfam05483  665 DKKISEEKLLEEVEKAKAIADEAVKLQ---------KEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSEL 727
mukB PRK04863
chromosome partition protein MukB;
2469-2911 1.80e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 50.73  E-value: 1.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2469 ERLEKVVQEQEKSlehlrASDRSSLLSEIQALRA--QLRMTHLQNQEKLQQLCAALTSAEARgsrqehqLRRQVELLAyk 2546
Cdd:PRK04863   307 YRLVEMARELAEL-----NEAESDLEQDYQAASDhlNLVQTALRQQEKIERYQADLEELEER-------LEEQNEVVE-- 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2547 VEQEKRIASDVQKTLTEEQekassvrkllvveqtvVRDLRSELRECKQdnerllaSLGEAQKEVLQLR---SVLDSKESN 2623
Cdd:PRK04863   373 EADEQQEENEARAEAAEEE----------------VDELKSQLADYQQ-------ALDVQQTRAIQYQqavQALERAKQL 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2624 LRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRaslekQFAQSSQLCVALKHE-------QTAKDNLQK 2696
Cdd:PRK04863   430 CGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHS-----QFEQAYQLVRKIAGEvsrseawDVARELLRR 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2697 --ELQIEASRCEALlaqeRGQLSELQRSLEAEKgrslelaaalRHERLLTE---QLSRGP-------RESPAHHALLRKL 2764
Cdd:PRK04863   505 lrEQRHLAEQLQQL----RMRLSELEQRLRQQQ----------RAERLLAEfckRLGKNLddedeleQLQEELEARLESL 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2765 KEEKSRAAELQARLEQVQRQQEADVQKRRAeleREKEVRAAQARepgrclrreghasqqqagLEPLQAglaaQEGRKDAR 2844
Cdd:PRK04863   571 SESVSEARERRMALRQQLEQLQARIQRLAA---RAPAWLAAQDA------------------LARLRE----QSGEEFED 625

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953050669 2845 RADVgpgraDAEMRPTgaKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAaqrpEAERLQE--ERLG 2911
Cdd:PRK04863   626 SQDV-----TEYMQQL--LERERELTVERDELAARKQALDEEIERLSQPGGS----EDPRLNAlaERFG 683
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2468-2679 2.40e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 2.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2468 LERLEKVVQEQEKSLEHLRAsDRSSLLSEIQALRAQLRMTHLQ---NQEKLQQLCAALTSAEARGSRQEHQLRRQVELLA 2544
Cdd:COG4942     29 LEQLQQEIAELEKELAALKK-EEKALLKQLAALERRIAALARRiraLEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2545 YKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDskesNL 2624
Cdd:COG4942    108 ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA----EL 183

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1953050669 2625 RAALQELESERGKERALQSRLE---EAQLQHLQREGQSSKTLEELRASLEKQFAQSSQ 2679
Cdd:COG4942    184 EEERAALEALKAERQKLLARLEkelAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 950-1607 2.89e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.06  E-value: 2.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  950 AELRQETGKQQLHCQEEPEVLecpsepfLEQQILQPKGEFESEKKvALHEKEihglecAQAQSLYQKEKEsLFLQLQEKN 1029
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAE-------LEEKLEELKEELESLEA-ELEELE------AELEELESRLEE-LEEQLETLR 385

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1030 NQILQLKEQILSLSHEVEERRRDLEQLQQRRERENQEGTNLismLKSDADLSDRERRALRDALRRLLSLFGEMLKVAIAL 1109
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEEL---LKKLEEAELKELQAELEELEEELEELQEELERLEEA 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1110 KSRISERVGLCLEDEDPPG-------------------------------AWPSGQALSAAPVLE--ETWPGSEAALLEL 1156
Cdd:TIGR02168  463 LEELREELEEAEQALDAAErelaqlqarldslerlqenlegfsegvkallKNQSGLSGILGVLSEliSVDEGYEAAIEAA 542

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1157 DRSLPECVEMPSEAEISSHICesfFMSPESS-----LEYEQPIRRIYQSLGLAVEGLLELALDSTRQLEEARqihSRFEK 1231
Cdd:TIGR02168  543 LGGRLQAVVVENLNAAKKAIA---FLKQNELgrvtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFD---PKLRK 616

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1232 EFS--------CKNEETAQVVRKQQQLLERL------------------EEENAARTRLMLELHQAQGIIEGFKEEKASL 1285
Cdd:TIGR02168  617 ALSyllggvlvVDDLDNALELAKKLRPGYRIvtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAEL 696

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1286 QEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEAsaaeaeareagtpapIAHEDSALRREVECLTQ 1365
Cdd:TIGR02168  697 EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ---------------LEERIAQLSKELTELEA 761

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1366 EQSEARKQSEKDRAALLSQMKVFEaELEEQLSRH-EACAKQAEELSALRQQMAALDKHLRSQRQfmDEQAVEREHEREEf 1444
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIE-ELEAQIEQLkEELKALREALDELRAELTLLNEEAANLRE--RLESLERRIAATE- 837

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1445 qREIQRLEEQLRQAArprphgprvSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCR 1524
Cdd:TIGR02168  838 -RRLEDLEEQIEELS---------EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1525 REAAQLREELERQRDAMKALQQDKEALQekqmsnlLLVSTLQSKL-DEGRCPVPPADSCPEGPEVQLEAVQRALQQRESE 1603
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLE-------VRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980


                   ....
gi 1953050669 1604 VLDL 1607
Cdd:TIGR02168  981 IKEL 984
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 2513-2796 5.24e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 49.28  E-value: 5.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2513 EKLQQLCAALTS-AEARGSRQEHQLRRQVellaykVEQEKRIASDVQKTLTEEQEKASSVRKLLVV---EQTVVrdlrse 2588
Cdd:PRK10929    45 EIVEALQSALNWlEERKGSLERAKQYQQV------IDNFPKLSAELRQQLNNERDEPRSVPPNMSTdalEQEIL------ 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2589 lreckQDNERLLASLGEAQKEVLQLRSVLDS------KESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSK- 2661
Cdd:PRK10929   113 -----QVSSQLLEKSRQAQQEQDRAREISDSlsqlpqQQTEARRQLNEIERRLQTLGTPNTPLAQAQLTALQAESAALKa 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2662 TLEELraslekQFAQSSqlcvALKHEQTAKdnLQKEL-QIEASRCEALLAQERGQLSElQRSLEAEKgrslelaaALRHE 2740
Cdd:PRK10929   188 LVDEL------ELAQLS----ANNRQELAR--LRSELaKKRSQQLDAYLQALRNQLNS-QRQREAER--------ALEST 246

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1953050669 2741 RLLTEQLSRGPRespahhALLRKLK--EEKSRAAELQA-RLEQV---QRQQEADVQKRRAEL 2796
Cdd:PRK10929   247 ELLAEQSGDLPK------SIVAQFKinRELSQALNQQAqRMDLIasqQRQAASQTLQVRQAL 302
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 137-875 5.88e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.07  E-value: 5.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  137 SLELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQeLALLRSRQQQELELAREQHAREQEEMRLRCSQ 216
Cdd:pfam12128  252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQ-WKEKRDELNGELSAADAAVAKDRSELEALEDQ 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  217 ETAKLKEKLQSEMERNARAvESLKRDWE--SERGLCLENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQA 294
Cdd:pfam12128  331 HGAFLDADIETAAADQEQL-PSWQSELEnlEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQ 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  295 ECALRTLEAQHEEALRQLREDLQSErcqyVQDLELRLRDQEVEKQLELESLRASYAEL--KAQSQEEIRRLWSQLESPRP 372
Cdd:pfam12128  410 LAVAEDDLQALESELREQLEAGKLE----FNEEEYRLKSRLGELKLRLNQATATPELLlqLENFDERIERAREEQEAANA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  373 DRQDAsartphgeeleQRERecgvqQQRRGRRAEQESELGQSPEGAVERgredpvllEQRLQDATEEPSLESGGIGPSSM 452
Cdd:pfam12128  486 EVERL-----------QSEL-----RQARKRRDQASEALRQASRRLEER--------QSALDELELQLFPQAGTLLHFLR 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  453 REGERREQRVGPSLQPELAenHRCHLTAwtssleaqqqaglVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDT 532
Cdd:pfam12128  542 KEAPDWEQSIGKVISPELL--HRTDLDP-------------EVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  533 EVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLEnrnlheklqhevclkedLERVKHSLvEDHREELKKANERLQLVKQE 612
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASRE-----------------ETFARTAL-KNARLDLRRLFDEKQSEKDK 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  613 LKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQsvinkfELREIKMRQLQDQQAaqildLEGSLVEQQGRLRQL 692
Cdd:pfam12128  669 KNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKE------QKREARTEKQAYWQV-----VEGALDAQLALLKAA 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  693 EHGLEAEECPRCGHCGQEPAGRVAPADQDWELATRRLREdcALQLMQAQSRFLKERKELTEKFTAEQDALLQEAQEKHAc 772
Cdd:pfam12128  738 IAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKRE--IRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLAT- 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  773 dmrlLQERHQQHVLSLTAQLeARRRAEVEELKASVESERWAL--AEARVAELQTEHAAAISALEARHSALLGSLESRHLS 850
Cdd:pfam12128  815 ----QLSNIERAISELQQQL-ARLIADTKLRRAKLEMERKASekQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIG 889

                          730       740
                   ....*....|....*....|....*
gi 1953050669  851 EVQAMREEHRQALEQLRVDLEKQLQ 875
Cdd:pfam12128  890 ERLAQLEDLKLKRDYLSESVKKYVE 914
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 88-382 6.07e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.97  E-value: 6.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669   88 QDREQDCKLEIAQPMGRQEDEAGAQQQVAVELRQPAGMQQVQLQTQPVPSLELEALRLSLSNMHTAQLELTQANLQKEKE 167
Cdd:pfam17380  298 QERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRM 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  168 TALTELRamlngrhaQELALLRSRQQQELELAREQHAREQEEMR-----------LRCSQETAKLKEKLQSEMERnARAV 236
Cdd:pfam17380  378 RELERLQ--------MERQQKNERVRQELEAARKVKILEEERQRkiqqqkvemeqIRAEQEEARQREVRRLEEER-AREM 448

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  237 ESLKRDwESERGLCLENLRRELSAKHRSELENLQDQFKRELSEQ------KAELEKIFQAKNQAECALRTLEAQHEEALR 310
Cdd:pfam17380  449 ERVRLE-EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEqrrkilEKELEERKQAMIEEERKRKLLEKEMEERQK 527

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953050669  311 QLREDLQSERCQyvqdlELRLRDQEVE--KQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDASARTP 382
Cdd:pfam17380  528 AIYEEERRREAE-----EERRKQQEMEerRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEATTP 596
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2471-2910 7.67e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.61  E-value: 7.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2471 LEKVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRM------THLQNQEKLQQLCAALTSAEARGSRQEHQLRR-QVELL 2543
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEaeekeeEYAELQEELEELEEELEELEAELEELREELEKlEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2544 AYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLG-EAQKEVLQLRSVLDSKES 2622
Cdd:COG4717    127 LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQ 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2623 NLRAALQELESERGKERALQSRLEeaQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEA 2702
Cdd:COG4717    207 RLAELEEELEEAQEELEELEEELE--QLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLG 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2703 SRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQ---LSRGPRESPAHHALLRKLKEEKSRAAELQARLE 2779
Cdd:COG4717    285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALglpPDLSPEELLELLDRIEELQELLREAEELEEELQ 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2780 QVQRQQEADVQKRRAELEREKEVRAAqarepgrcLRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRp 2859
Cdd:COG4717    365 LEELEQEIAALLAEAGVEDEEELRAA--------LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELE- 435

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1953050669 2860 tGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERL 2910
Cdd:COG4717    436 -ELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAEL 485
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1352-1751 7.86e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 48.35  E-value: 7.86e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1352 EDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQR---- 1427
Cdd:pfam07888   49 AQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRaahe 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1428 ----------QFMDEQAVEREHEREEFQREIQRLEEQLRQAArprphgprvSDEEQLDEEVELLQEKLREKSDGFNELVI 1497
Cdd:pfam07888  129 arireleediKTLTQRVLERETELERMKERAKKAGAQRKEEE---------AERKQLQAKLQQTEEELRSLSKEFQELRN 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1498 KKELADRQVMIQEEEIRRLEETNASCRREAAQ---LREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRc 1574
Cdd:pfam07888  200 SLAQRDTQVLQLQDTITTLTQKLTTAHRKEAEneaLLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQAR- 278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1575 pvppadscpegpevqLEAVQRALQQRESEvLDLKEQLGKMkddlvSKSDEVLHLNLELDAQSsraavsVRELQEENASLK 1654
Cdd:pfam07888  279 ---------------LQAAQLTLQLADAS-LALREGRARW-----AQERETLQQSAEADKDR------IEKLSAELQRLE 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1655 AFLQNKEKEimcvSEQLEAQLAGMGSGALREVTyDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELS 1734
Cdd:pfam07888  332 ERLQEERME----REKLEVELGREKDCNRVQLS-ESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETVAD 406

                          410
                   ....*....|....*..
gi 1953050669 1735 LGAPAVPAAVDCELPAV 1751
Cdd:pfam07888  407 AKWSEAALTSTERPDSP 423
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1238-1560 8.07e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.61  E-value: 8.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1238 EETAQVVRKQQQLLERLEEENAARTRLMLEL-HQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQ 1316
Cdd:COG4717    156 EELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1317 QAELKEEN------------------SALWSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQSEARKQSEKDR 1378
Cdd:COG4717    236 LEAAALEErlkearlllliaaallalLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEE 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1379 ---AALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMD----------------EQAVEREH 1439
Cdd:COG4717    316 leeEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEiaallaeagvedeeelRAALEQAE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1440 EREEFQREIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNELviKKELADRQVMIQE-EEIRRLEE 1518
Cdd:COG4717    396 EYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEEL--REELAELEAELEQlEEDGELAE 473

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1953050669 1519 TNASCRREAAQLREELER---QRDAMKALQQDKEALQEKQMSNLL 1560
Cdd:COG4717    474 LLQELEELKAELRELAEEwaaLKLALELLEEAREEYREERLPPVL 518
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1356-1733 8.15e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.50  E-value: 8.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1356 LRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEE--------LSALRQQMAALDKhLRSQR 1427
Cdd:PRK02224   182 LSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQAREtrdeadevLEEHEERREELET-LEAEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1428 QFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDEEQLDEE-VELLQEKLREKSDGfnelvIKKELADRQV 1506
Cdd:PRK02224   261 EDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEaVEARREELEDRDEE-----LRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1507 MIQE---------EEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKqmsnlllvstlqskLDEGRCPVp 1577
Cdd:PRK02224   336 AAQAhneeaeslrEDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEE--------------IEELRERF- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1578 padscpEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDA----------QSSRAAVSVRELQ 1647
Cdd:PRK02224   401 ------GDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDR 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1648 EENASLKAFLQNKEKEIMCVSEQLEA--QLAGMGSG---------ALREVTYDRSSEIEELRSIIENLRENQQRLQKEKA 1716
Cdd:PRK02224   475 ERVEELEAELEDLEEEVEEVEERLERaeDLVEAEDRierleerreDLEELIAERRETIEEKRERAEELRERAAELEAEAE 554

                          410
                   ....*....|....*..
gi 1953050669 1717 EEMEQLHEVIERLQEEL 1733
Cdd:PRK02224   555 EKREAAAEAEEEAEEAR 571
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1245-1918 1.06e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 1.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1245 RKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKeekaSLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEEN 1324
Cdd:pfam12128  217 RLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFN----TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLL 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1325 SAL---WSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEA 1401
Cdd:pfam12128  293 RTLddqWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQD 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1402 CAKQAEELSALRQQ-----MAALDKHLRSQRQFMDEQAVErehEREEFQREIQRLEEQLRQAARprphgprvsdeeQLDE 1476
Cdd:pfam12128  373 VTAKYNRRRSKIKEqnnrdIAGIKDKLAKIREARDRQLAV---AEDDLQALESELREQLEAGKL------------EFNE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1477 EVELLQEKLREKSDGFNELVIKKELADrQVMIQEEEIRRLEETNASCRREAAQLREELERQR----DAMKALQQDKEALQ 1552
Cdd:pfam12128  438 EEYRLKSRLGELKLRLNQATATPELLL-QLENFDERIERAREEQEAANAEVERLQSELRQARkrrdQASEALRQASRRLE 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1553 EKQMSnlllVSTLQSKLDegrcpvPPADSCpegpevqleavqraLQQRESEVLDLKEQLGKMKD-------DLVSKSDE- 1624
Cdd:pfam12128  517 ERQSA----LDELELQLF------PQAGTL--------------LHFLRKEAPDWEQSIGKVISpellhrtDLDPEVWDg 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1625 -------VLHLNLELDA-QSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLeaqlaGMGSGALREVtydrSSEIEE 1696
Cdd:pfam12128  573 svggelnLYGVKLDLKRiDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQL-----VQANGELEKA----SREETF 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1697 LRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEElslgapAVPAAVDCElpavpapavgpeaLAAAGAASRLFAEQEH 1776
Cdd:pfam12128  644 ARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDS------ANERLNSLE-------------AQLKQLDKKHQAWLEE 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1777 RHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMASQIQAFE-------AALRAKEARLAERDLEIDAMKRqK 1849
Cdd:pfam12128  705 QKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALEtwykrdlASLGVDPDVIAKLKREIRTLER-K 783

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953050669 1850 LAHSAELETILAAFSRFRR---TLERQPLAAEDEPPE--LQRLRVQCVRLSRQLQVLNQRFLRCQKEADKQQAR 1918
Cdd:pfam12128  784 IERIAVRRQEVLRYFDWYQetwLQRRPRLATQLSNIEraISELQQQLARLIADTKLRRAKLEMERKASEKQQVR 857
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1216-1904 1.07e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.14  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1216 TRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERL----EEENAARTRLMLELH----QAQGIIEGFKEEKASLQE 1287
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEaeiaSLERSIAEKERELEDAEE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1288 ALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALwSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQ 1367
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL-KEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1368 SE-----ARKQSEKDR------------AALLSQMKVFEAELEEqlsRHEACAKQAEELSALRQQMAALDKHLRSQRQfm 1430
Cdd:TIGR02169  402 NElkrelDRLQEELQRlseeladlnaaiAGIEAKINELEEEKED---KALEIKKQEWKLEQLAADLSKYEQELYDLKE-- 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1431 DEQAVEREheREEFQREIQRLEEQLRQAARPRPHGPRVsdEEQLDEEVELLQEKLRE----------------------- 1487
Cdd:TIGR02169  477 EYDRVEKE--LSKLQRELAEAEAQARASEERVRGGRAV--EEVLKASIQGVHGTVAQlgsvgeryataievaagnrlnnv 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1488 --KSDGFNELVI---KKELADRQVMIQEEEIRRLEETNASCRRE-----AAQLREELERQRDAMKALQQDKEALQE---- 1553
Cdd:TIGR02169  553 vvEDDAVAKEAIellKRRKAGRATFLPLNKMRDERRDLSILSEDgvigfAVDLVEFDPKYEPAFKYVFGDTLVVEDieaa 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1554 -KQMSNLLLVsTLQSKLDEgrcpvpPADSCPEGPEVQLEAVQRALQQREsEVLDLKEQLGKMKDDLVSKSDEVLHLNLEL 1632
Cdd:TIGR02169  633 rRLMGKYRMV-TLEGELFE------KSGAMTGGSRAPRGGILFSRSEPA-ELQRLRERLEGLKRELSSLQSELRRIENRL 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1633 DAQSSRAAVSVRELQEenaslkaflqnKEKEImcvsEQLEAQLAgmgsgALREVTYDRSSEIEELRSIIENLRENQQRLQ 1712
Cdd:TIGR02169  705 DELSQELSDASRKIGE-----------IEKEI----EQLEQEEE-----KLKERLEELEEDLSSLEQEIENVKSELKELE 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1713 KEKAEEMEQLHEvierLQEELSlgapavpaavdcELPAVPAPAVGPEALAAAGAASRLFAEQEHRhGQALEALQQRLQAA 1792
Cdd:TIGR02169  765 ARIEELEEDLHK----LEEALN------------DLEARLSHSRIPEIQAELSKLEEEVSRIEAR-LREIEQKLNRLTLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1793 EEAAAGQLAELERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEIdamkrqklahsAELETILAAFSRFRRTLER 1872
Cdd:TIGR02169  828 KEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL-----------RDLESRLGDLKKERDELEA 896

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 1953050669 1873 QPLAAEDEPPEL----QRLRVQCVRLSRQLQVLNQR 1904
Cdd:TIGR02169  897 QLRELERKIEELeaqiEKKRKRLSELKAKLEALEEE 932
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1643-1728 1.45e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.55  E-value: 1.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1643 VRELQEENASLKAFLQNKEKEImcvsEQLEAQLAGMGSGALREVTYDRS-----SEIEELRSIIENLRENQQRLqKEKAE 1717
Cdd:COG2433    422 VERLEAEVEELEAELEEKDERI----ERLERELSEARSEERREIRKDREisrldREIERLERELEEERERIEEL-KRKLE 496

                           90
                   ....*....|.
gi 1953050669 1718 EMEQLHEVIER 1728
Cdd:COG2433    497 RLKELWKLEHS 507
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2626-2858 1.46e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2626 AALQELESERGKERALQSRLEEAQlQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRC 2705
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELE-KELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2706 EALLAQERGQLSELQRSLEAEKGRSL--------ELAAALRHERLLTEQlsrgpreSPAHHALLRKLKEEKSRAAELQAR 2777
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPlalllspeDFLDAVRRLQYLKYL-------APARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2778 LEQVQRQQE---ADVQKRRAELEREKEVRAAQAREPGRCLRREGHA----SQQQAGLEPLQAGLAAQEGRKDARRADVGP 2850
Cdd:COG4942    169 LEAERAELEallAELEEERAALEALKAERQKLLARLEKELAELAAElaelQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ....*...
gi 1953050669 2851 GRADAEMR 2858
Cdd:COG4942    249 AALKGKLP 256
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1432-1548 1.52e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.55  E-value: 1.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1432 EQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDE-EQLDEEVELLQEKLREKSDGFNElvikKELADRQVMIQE 1510
Cdd:COG2433    396 EAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAElEEKDERIERLERELSEARSEERR----EIRKDREISRLD 471

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1953050669 1511 EEIRRLEETNASCRREAAQLREELERQRDAMKALQQDK 1548
Cdd:COG2433    472 REIERLERELEEERERIEELKRKLERLKELWKLEHSGE 509
mukB PRK04863
chromosome partition protein MukB;
2605-2907 1.55e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 1.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2605 EAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQ---------LQHLQREGQSSKTLEELRASLEKQfa 2675
Cdd:PRK04863   290 ELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASdhlnlvqtaLRQQEKIERYQADLEELEERLEEQ-- 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2676 qssQLCVALKHEQtakdnlQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRH-ERllTEQLSRGPRES 2754
Cdd:PRK04863   368 ---NEVVEEADEQ------QEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQAlER--AKQLCGLPDLT 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2755 PA-----HHALLRKLKE--EKSRAAELQARLEQVQRQQEADVQK--RRAELEREKEVRAAQAREPGRCLRREGHASQQqa 2825
Cdd:PRK04863   437 ADnaedwLEEFQAKEQEatEELLSLEQKLSVAQAAHSQFEQAYQlvRKIAGEVSRSEAWDVARELLRRLREQRHLAEQ-- 514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2826 gLEPLQAGLAAQEGR----KDARR----------------ADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQR 2885
Cdd:PRK04863   515 -LQQLRMRLSELEQRlrqqQRAERllaefckrlgknlddeDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQA 593

                          330       340
                   ....*....|....*....|....
gi 1953050669 2886 TVQALEAKEEA--AQRPEAERLQE 2907
Cdd:PRK04863   594 RIQRLAARAPAwlAAQDALARLRE 617
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1355-1557 1.66e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1355 ALRREVECLTQEQSEARKQSEKDRAALlsqmkvfeAELEEQLSRHEACAKQAEE---LSALRQQMAALDKHLRSQRQFMD 1431
Cdd:COG4913    614 ALEAELAELEEELAEAEERLEALEAEL--------DALQERREALQRLAEYSWDeidVASAEREIAELEAELERLDASSD 685

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1432 E-QAVEREheREEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREKSDgfnelvikkELADRQVMIQE 1510
Cdd:COG4913    686 DlAALEEQ--LEELEAELEELEEELDELKG---------EIGRLEKELEQAEEELDELQD---------RLEAAEDLARL 745

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1953050669 1511 EEIRRLEET--NASCRREAAQLREELERQRDAMKALQQDKEALQEKQMS 1557
Cdd:COG4913    746 ELRALLEERfaAALGDAVERELRENLEERIDALRARLNRAEEELERAMR 794
PRK11281 PRK11281
mechanosensitive channel MscK;
2474-2748 2.12e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.21  E-value: 2.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2474 VVQEQEKSLEHLRASDRSSllSEIQALRAQL-----RMThlQNQEKLQQLCAALTSA-------------EARGSRQEHQ 2535
Cdd:PRK11281    61 VQQDLEQTLALLDKIDRQK--EETEQLKQQLaqapaKLR--QAQAELEALKDDNDEEtretlstlslrqlESRLAQTLDQ 136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2536 LRR-QVELLAYKVE------QEKRiasdVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQK 2608
Cdd:PRK11281   137 LQNaQNDLAEYNSQlvslqtQPER----AQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQR 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2609 EVLQLRSVLdskesnlraalQELESERGKERALQSRLEEAQLQHLQ------REGQSSKTLEELRASLEKQFAQSSQLcv 2682
Cdd:PRK11281   213 KSLEGNTQL-----------QDLLQKQRDYLTARIQRLEHQLQLLQeainskRLTLSEKTVQEAQSQDEAARIQANPL-- 279

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953050669 2683 alkheqtakdnLQKELQIEASRCEALLAQERgQLSEL-QRSLEAEKgrslELAAALRHERLLTEQLS 2748
Cdd:PRK11281   280 -----------VAQELEINLQLSQRLLKATE-KLNTLtQQNLRVKN----WLDRLTQSERNIKEQIS 330
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 169-439 2.23e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 2.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  169 ALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAvESLKRDWESERG 248
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI-EQLEQEEEKLKE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  249 LcLENLRRELSAKHRsELENLqdqfKRELSEQKAELEKIFQAKNQAECALRTLEAQ-HEEALRQLREDLQSERcQYVQDL 327
Cdd:TIGR02169  738 R-LEELEEDLSSLEQ-EIENV----KSELKELEARIEELEEDLHKLEEALNDLEARlSHSRIPEIQAELSKLE-EEVSRI 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  328 ELRLrdQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS----------ARTPHGEELEQRERECGVQ 397
Cdd:TIGR02169  811 EARL--REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLngkkeeleeeLEELEAALRDLESRLGDLK 888

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1953050669  398 QQRRGRRA---EQESELGQSpEGAVERGREDPVLLEQRLQDATEE 439
Cdd:TIGR02169  889 KERDELEAqlrELERKIEEL-EAQIEKKRKRLSELKAKLEALEEE 932
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2480-2908 2.30e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.14  E-value: 2.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2480 KSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRR-----------QVELLAYKVE 2548
Cdd:pfam12128  268 KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEAledqhgafldaDIETAAADQE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2549 QEKRIASDVQ------KTLTEEQ---EKASSVRKLLVVEQ--TVVRDLRSELRECKQDNERLLASL-GEAQKEVLQLRSV 2616
Cdd:pfam12128  348 QLPSWQSELEnleerlKALTGKHqdvTAKYNRRRSKIKEQnnRDIAGIKDKLAKIREARDRQLAVAeDDLQALESELREQ 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2617 LDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREgQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQK 2696
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLE-NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASE 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2697 ELQieasRCEALLAQERGQLSELQRSLEAEKGRSLE----------------LAAALRHERLLTEQLSRGPR-------- 2752
Cdd:pfam12128  507 ALR----QASRRLEERQSALDELELQLFPQAGTLLHflrkeapdweqsigkvISPELLHRTDLDPEVWDGSVggelnlyg 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2753 --------ESPAHHALLRKLKEEKSRAAE-LQARLEQVQRQQEADVQKRRA-ELEREKEVRAAQAREPGRcLRREGHASQ 2822
Cdd:pfam12128  583 vkldlkriDVPEWAASEEELRERLDKAEEaLQSAREKQAAAEEQLVQANGElEKASREETFARTALKNAR-LDLRRLFDE 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2823 QQAGLEPLQAGLAAQEGRKDARRADVgpgraDAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEA 2902
Cdd:pfam12128  662 KQSEKDKKNKALAERKDSANERLNSL-----EAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKA 736


                   ....*.
gi 1953050669 2903 ERLQEE 2908
Cdd:pfam12128  737 AIAARR 742
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1354-1731 2.38e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.94  E-value: 2.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1354 SALRREVECLTQEQSEARKQSEKDraalLSQMKVFEAELEEQLsrheacakqaEELSALRQQMAALDKHLRSQR---QFM 1430
Cdd:TIGR04523  345 SQLKKELTNSESENSEKQRELEEK----QNEIEKLKKENQSYK----------QEIKNLESQINDLESKIQNQEklnQQK 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1431 DEQAVEREHEREEFQREIQRLEEQLrqaarprphgprvsdeEQLDEEVELLQEKLREKSDGFNELVIKKEladrqvmIQE 1510
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETI----------------IKNNSEIKDLTNQDSVKELIIKNLDNTRE-------SLE 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1511 EEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKqmsnlllVSTLQSKLDEgrcpvppadscpegPEVQL 1590
Cdd:TIGR04523  468 TQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEK-------VKDLTKKISS--------------LKEKI 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1591 EAVQRALQQRESEVLDLKEQLGKMKDDLVSKS--DEVLHLNLELDaqssraavsvrELQEENASLKA-------FLQNKE 1661
Cdd:TIGR04523  527 EKLESEKKEKESKISDLEDELNKDDFELKKENleKEIDEKNKEIE-----------ELKQTQKSLKKkqeekqeLIDQKE 595

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1662 KEIMCVSEQLEAQlaGMGSGALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQE 1731
Cdd:TIGR04523  596 KEKKDLIKEIEEK--EKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPE 663
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
164-314 2.39e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 2.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  164 KEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRlRCSQETAKLKEKL----QSEMERNARAVESL 239
Cdd:COG4913    265 AAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELE-RLEARLDALREELdeleAQIRGNGGDRLEQL 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  240 KRD---WESERGLCLENLRR--------ELSAKH-RSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEE 307
Cdd:COG4913    344 EREierLERELEERERRRARleallaalGLPLPAsAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRE 423


                   ....*..
gi 1953050669  308 ALRQLRE 314
Cdd:COG4913    424 LEAEIAS 430
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2537-2796 2.60e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 2.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2537 RRQVELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVR------DLRSELRECkQDNERLLASLGEAQKEV 2610
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeiDVASAEREI-AELEAELERLDASSDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2611 LQLRSVLDSKESNLRAALQELESERGKERALQSRLEEA--QLQHLQR--EGQSSKTLEELRASLEKQFAQSSQlcvaLKH 2686
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAeeELDELQDrlEAAEDLARLELRALLEERFAAALG----DAV 763

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2687 EQTAKDNLQKE---LQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALR--HERLLTEQLsrgpresPAHHALL 2761
Cdd:COG4913    764 ERELRENLEERidaLRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLalLDRLEEDGL-------PEYEERF 836

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1953050669 2762 RKLKEEKSRA--AELQARLeqvqRQQEADVQKRRAEL 2796
Cdd:COG4913    837 KELLNENSIEfvADLLSKL----RRAIREIKERIDPL 869
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1219-1838 2.60e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.97  E-value: 2.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1219 LEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCR------- 1291
Cdd:TIGR02168  290 LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEleaelee 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1292 QETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKeasaaeaeareagtpapiahedSALRREVECLTQEQSEAR 1371
Cdd:TIGR02168  370 LESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL----------------------ERLEDRRERLQQEIEELL 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1372 KQ-SEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQR 1450
Cdd:TIGR02168  428 KKlEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG 507

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1451 LEEQLRQAARPRPHGPRVSDEEQLDEEVEL-LQEKLREKSDgfNELVIKKELADRQV--MIQEEEIRR--LEETNASCRR 1525
Cdd:TIGR02168  508 VKALLKNQSGLSGILGVLSELISVDEGYEAaIEAALGGRLQ--AVVVENLNAAKKAIafLKQNELGRVtfLPLDSIKGTE 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1526 EAAQLREELERQRDAMKALQQDKEALQEKQ------MSNLLLVSTLQS------KLDEGRCPVPPAD------------- 1580
Cdd:TIGR02168  586 IQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsylLGGVLVVDDLDNalelakKLRPGYRIVTLDGdlvrpggvitggs 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1581 ------------------SCPEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELD---AQSSRA 1639
Cdd:TIGR02168  666 aktnssilerrreieeleEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLArleAEVEQL 745

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1640 AVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGS------GALREVTYDRSsEIEELRSIIENLRENQQRLQ- 1712
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEleaqieQLKEELKALRE-ALDELRAELTLLNEEAANLRe 824

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1713 ---------KEKAEEMEQLHEVIERLQEELSLGAPAVPaavDCELPAvpapavgPEALAAAGAASRLFAEQEHRHGQALE 1783
Cdd:TIGR02168  825 rleslerriAATERRLEDLEEQIEELSEDIESLAAEIE---ELEELI-------EELESELEALLNERASLEEALALLRS 894

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1953050669 1784 ALQQRLQAAEEAAAGQLAELERSAALREAEVQaMASQIQAFEAALRAKEARLAER 1838
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQ-LELRLEGLEVRIDNLQERLSEE 948
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 949-1732 3.16e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.89  E-value: 3.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  949 LAELRQETGKQQLHCQEEPEVLECPSEPfLEQQILQPKGEFESEKKVALHEKEIHGlECAQAQSLYQKEKESLFLQLQEK 1028
Cdd:pfam02463  221 LEEEYLLYLDYLKLNEERIDLLQELLRD-EQEEIESSKQEIEKEEEKLAQVLKENK-EEEKEKKLQEEELKLLAKEEEEL 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1029 NNQILQLKEQILSLSHEVEERRRDLEQLQQRRERENQEGTNLISMLKSdADLSDRERRALRDALRRLLSLFGEMLKVAIA 1108
Cdd:pfam02463  299 KSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKE-LEIKREAEEEEEEELEKLQEKLEQLEEELLA 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1109 LKSRISERVGLCLEDEDPPGAWPSGQALSAAPVLEETWPGSEAALLELDRSLPECVEMPSEAE-------ISSHICESFF 1181
Cdd:pfam02463  378 KKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIElkqgkltEEKEELEKQE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1182 MSPESSLEYEQPIRRIYQSLGLAVEGLLELALDSTRQLEEARQ----IHSRFEKEFSCKNEETAQVVRKQQQLLERLEE- 1256
Cdd:pfam02463  458 LKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQkeskARSGLKVLLALIKDGVGGRIISAHGRLGDLGVa 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1257 ----ENAARTRLMLELHQAQGIIEGFKEEKASL--------------QEALCRQETAEHGLAEELEGLRQQLQQAAQQQA 1318
Cdd:pfam02463  538 venyKVAISTAVIVEVSATADEVEERQKLVRALtelplgarklrlliPKLKLPLKSIAVLEIDPILNLAQLDKATLEADE 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1319 ELKEENSALWSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQlSR 1398
Cdd:pfam02463  618 DDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEI-LR 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1399 HEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRqaarprphgprvSDEEQLDEEV 1478
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEK------------SRLKKEEKEE 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1479 ELLQEKLREKSdgfNELVIKKELADRQVMIQEEEIRRLEETNAScRREAAQLREELERQRDAMKALQQDKEALQEKQMSN 1558
Cdd:pfam02463  765 EKSELSLKEKE---LAEEREKTEKLKVEEEKEEKLKAQEEELRA-LEEELKEEAELLEEEQLLIEQEEKIKEEELEELAL 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1559 LLLVSTLQSKLDEGRcpvppadscpegpEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSR 1638
Cdd:pfam02463  841 ELKEEQKLEKLAEEE-------------LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQ 907

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1639 AAVSVRELQEENASLKAFLQNKE--KEIMCVSEQLEAQLAGMGSGALREVTYDRSSEIEELRSIIENLRENQQRLQKEKA 1716
Cdd:pfam02463  908 KLNLLEEKENEIEERIKEEAEILlkYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKE 987

                          810
                   ....*....|....*.
gi 1953050669 1717 EEMEQLHEVIERLQEE 1732
Cdd:pfam02463  988 ERYNKDELEKERLEEE 1003
PTZ00121 PTZ00121
MAEBL; Provisional
 1214-1548 3.25e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 3.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1214 DSTRQLEEARQIHSRFEKEFSCKNEET--AQVVRKQQQLlERLEEENAARTRLMLELHQAQgiiEGFKEEKASLQEALCR 1291
Cdd:PTZ00121  1525 DEAKKAEEAKKADEAKKAEEKKKADELkkAEELKKAEEK-KKAEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKL 1600

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1292 QETAEHGLAEELEglrqQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQ---- 1367
Cdd:PTZ00121  1601 YEEEKKMKAEEAK----KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkk 1676

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1368 -SEARKQSEKDR-AALLSQMKVFEAELEEQLSRHEAC-AKQAEELsalrqqmaaldKHLRSQRQFMDEQAvEREHEREEF 1444
Cdd:PTZ00121  1677 aEEAKKAEEDEKkAAEALKKEAEEAKKAEELKKKEAEeKKKAEEL-----------KKAEEENKIKAEEA-KKEAEEDKK 1744

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1445 QREIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNELVIK--KELADRQVMIQEEEIRRLEETNAS 1522
Cdd:PTZ00121  1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKkiKDIFDNFANIIEGGKEGNLVINDS 1824

                          330       340
                   ....*....|....*....|....*....
gi 1953050669 1523 CRREAAQLREELER---QRDAMKALQQDK 1548
Cdd:PTZ00121  1825 KEMEDSAIKEVADSknmQLEEADAFEKHK 1853
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1438-1858 3.37e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.57  E-value: 3.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1438 EHEREEFQREIQRLEEQLRQAARPRphgprvsdeeqldEEVELLQEKLREKSDGFNELvikkeladrqvmiqEEEIRRLE 1517
Cdd:PRK02224   212 ESELAELDEEIERYEEQREQARETR-------------DEADEVLEEHEERREELETL--------------EAEIEDLR 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1518 ETNASCRREAAQLREELERQRDAmkalqqdkealqekqmsnlllVSTLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRAL 1597
Cdd:PRK02224   265 ETIAETEREREELAEEVRDLRER---------------------LEELEEERDDLLAEAGLDDADAEAVEARREELEDRD 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1598 QQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNleldaqsSRAAvsvrELQEENASLKAFLQNKEKEIMCVSEQLEAQLAG 1677
Cdd:PRK02224   324 EELRDRLEECRVAAQAHNEEAESLREDADDLE-------ERAE----ELREEAAELESELEEAREAVEDRREEIEELEEE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1678 MGSgaLREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEelslgAPAVPAAVDCelpavpapavg 1757
Cdd:PRK02224   393 IEE--LRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-----AEALLEAGKC----------- 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1758 PEALAAAGAASRLFAEQEHRhgQALEALQQRLQAAEEAAAGQLAELERSAALREAE--VQAMASQIQAFEAALRAKEARL 1835
Cdd:PRK02224   455 PECGQPVEGSPHVETIEEDR--ERVEELEAELEDLEEEVEEVEERLERAEDLVEAEdrIERLEERREDLEELIAERRETI 532

                          410       420
                   ....*....|....*....|...
gi 1953050669 1836 AERDLEIDAMKRQKLAHSAELET 1858
Cdd:PRK02224   533 EEKRERAEELRERAAELEAEAEE 555
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 2596-2908 3.40e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 3.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2596 NER--LLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQ---------LQHLQREGQSSKTLE 2664
Cdd:COG3096    278 NERreLSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASdhlnlvqtaLRQQEKIERYQEDLE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2665 ELRASLEKQfaqssQLCVALKHEQtakdnlQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRH-ERll 2743
Cdd:COG3096    358 ELTERLEEQ-----EEVVEEAAEQ------LAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQAlEK-- 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2744 TEQLSRGPRESPA-----HHALLRKLKE--EKSRAAELQARLEQVQRQQ-----------------EADVQKRRAELERE 2799
Cdd:COG3096    425 ARALCGLPDLTPEnaedyLAAFRAKEQQatEEVLELEQKLSVADAARRQfekayelvckiageverSQAWQTARELLRRY 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2800 KEVRAAQAREPG--RCLRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELELQRQRDE 2877
Cdd:COG3096    505 RSQQALAQRLQQlrAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELR 584

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1953050669 2878 HKIRQLQRTVQALEAKEEA--AQRPEAERLQEE 2908
Cdd:COG3096    585 QQLEQLRARIKELAARAPAwlAAQDALERLREQ 617
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2518-2756 5.69e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 5.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2518 LCAALTSAEARGSRQEHQLRRQvellaykvEQEKRIASdVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNE 2597
Cdd:COG4942      9 LLLALAAAAQADAAAEAEAELE--------QLQQEIAE-LEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2598 RLLASLGEAQKEVLQLRSVLDSKESNLR---AALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQF 2674
Cdd:COG4942     80 ALEAELAELEKEIAELRAELEAQKEELAellRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADL 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2675 AQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRES 2754
Cdd:COG4942    160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239


                   ..
gi 1953050669 2755 PA 2756
Cdd:COG4942    240 AE 241
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 2465-2807 6.26e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.48  E-value: 6.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2465 SSLLERLEKVVQEQEKSLEHLRA--SDRSSLLSEiqalRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVEL 2542
Cdd:pfam05483  390 SSELEEMTKFKNNKEVELEELKKilAEDEKLLDE----KKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTS 465

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2543 LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVR---DLRSELRE-------CKQDNERLLASLGEAQKEVLQ 2612
Cdd:pfam05483  466 EEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQeasDMTLELKKhqediinCKKQEERMLKQIENLEEKEMN 545

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2613 LRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLE---KQFAQSSQLCVALKHEQT 2689
Cdd:pfam05483  546 LRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEnknKNIEELHQENKALKKKGS 625

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2690 AKDNLQKELQIEASRCEALLAQERGQLSEL----QRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPahhallrklK 2765
Cdd:pfam05483  626 AENKQLNAYEIKVNKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEID---------K 696

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1953050669 2766 EEKSRAAELQARLEQVQRQQEADVQKRRAEL----EREKEVRAAQA 2807
Cdd:pfam05483  697 RCQHKIAEMVALMEKHKHQYDKIIEERDSELglykNKEQEQSSAKA 742
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2486-2717 6.71e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2486 RASDRSSLLSEIQALRAQLRmthlQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRIASDVQKTLTEEQ 2565
Cdd:COG4942     25 AEAELEQLQQEIAELEKELA----ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2566 EKASSVRKLLVVEQTVVRDLRSEL---RECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQ 2642
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1953050669 2643 SRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEAL-LAQERGQLS 2717
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAgFAALKGKLP 256
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 126-346 6.80e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 6.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  126 QQVQLQTQPVPSLELEALRLSLSNMHTAQleltQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELarEQHAR 205
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELES----KLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL--ESRLE 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  206 EQEEMRLRCSQETAKLKEKLQSEMERNARAVESLKRDWESerglcLENLRRELSAKHRSELENLQDQFKRELSEQKAELE 285
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDR-----RERLQQEIEELLKKLEEAELKELQAELEELEEELE 450

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953050669  286 KIFQAKNQAECALRTLE---AQHEEALRQLREDLQ--SERCQYVQDLELRLRD-QEVEKQLELESLR 346
Cdd:TIGR02168  451 ELQEELERLEEALEELReelEEAEQALDAAERELAqlQARLDSLERLQENLEGfSEGVKALLKNQSG 517
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2642-3006 7.03e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 7.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2642 QSRLEEAQlQHLQREGQsskTLEELRASLEKQFAQSSQlCVALKHEQTAKDNLQKELQIeasrceALLAQERGQLSELQR 2721
Cdd:TIGR02168  178 ERKLERTR-ENLDRLED---ILNELERQLKSLERQAEK-AERYKELKAELRELELALLV------LRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2722 SLEAEKGRSLELAAALRherLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQeadvQKRRAELEREKE 2801
Cdd:TIGR02168  247 ELKEAEEELEELTAELQ---ELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQIL----RERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2802 VRAAQAREPGR---CLRREGHASQQQagLEPLQAGLAAQEGRKDARRADvgpgRADAEMRPTGAKEKLRELELQRQRDEH 2878
Cdd:TIGR02168  320 ELEAQLEELESkldELAEELAELEEK--LEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2879 KIRQLQRTVQALEAKEEAAQRpEAERLQEERLGLERvrqQLLCAAGLLTSFISRTVDRTISDWTSSNEKAVTsLLHTLEE 2958
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLED-RRERLQQEIEELLK---KLEEAELKELQAELEELEEELEELQEELERLEE-ALEELRE 468

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2959 LKSELSTPSSSQKKMTAELQTQL--VDVLLKDNDSLTKALRTVTQEKAEL 3006
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQARLdsLERLQENLEGFSEGVKALLKNQSGL 518
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 2461-2922 7.50e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.34  E-value: 7.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2461 PGEHSSLLERLEKVVQEQEKSLEHLRASdrSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQV 2540
Cdd:TIGR00618  162 SKEKKELLMNLFPLDQYTQLALMEFAKK--KSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQ 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2541 ELLAYKVEQEkriasdvqktltEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERL-----LASLGEAQKEVLQLRS 2615
Cdd:TIGR00618  240 QSHAYLTQKR------------EAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERInrarkAAPLAAHIKAVTQIEQ 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2616 VLDSKESNLRAALQELESERGKERALQSRLEEAQ-----LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTA 2690
Cdd:TIGR00618  308 QAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEeqrrlLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2691 KDNLQKELQIEASRCEALLAQERGQLSELQRS-------LEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRK 2763
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFrdlqgqlAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQS 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2764 LKEEKSRAAELQARLEQVQR--QQEADVQKRRAELEREKEvraaqarepGRCLRREGHAsQQQAGLEPLQAGLAAQEgrk 2841
Cdd:TIGR00618  468 LKEREQQLQTKEQIHLQETRkkAVVLARLLELQEEPCPLC---------GSCIHPNPAR-QDIDNPGPLTRRMQRGE--- 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2842 dARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEaERLQEERLGLERVRQQLLC 2921
Cdd:TIGR00618  535 -QTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNIT-VRLQDLTEKLSEAEDMLAC 612


                   .
gi 1953050669 2922 A 2922
Cdd:TIGR00618  613 E 613
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 1353-1611 1.00e-03

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 44.84  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1353 DSALRREVECLTQEQSEARKQsekdraalLSQMKVFEAELEEQLsrHEAC-AKQAEelsalRQQMAALDKHLRSQRQfmD 1431
Cdd:pfam09726  418 EQELRSQISSLTSLERSLKSE--------LGQLRQENDLLQTKL--HNAVsAKQKD-----KQTVQQLEKRLKAEQE--A 480

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1432 EQAVEREHEREefqREIQRLEEQLRQAARPRPHGPRVsdeeqldEEVELLQEKLREKsdgfnELVIKKelADRQVMIQEE 1511
Cdd:pfam09726  481 RASAEKQLAEE---KKRKKEEEATAARAVALAAASRG-------ECTESLKQRKREL-----ESEIKK--LTHDIKLKEE 543

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1512 EIRRLEEtnascrrEAAQLREELERQRDA---MKALQ--QDKEALQEKQMSnlllvSTLQSKLDegrcpvppADSCPEGP 1586
Cdd:pfam09726  544 QIRELEI-------KVQELRKYKESEKDTevlMSALSamQDKNQHLENSLS-----AETRIKLD--------LFSALGDA 603

                          250       260
                   ....*....|....*....|....*
gi 1953050669 1587 EVQLEAVQRALQQRESEVLDLKEQL 1611
Cdd:pfam09726  604 KRQLEIAQGQIYQKDQEIKDLKQKI 628
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 154-875 1.14e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  154 QLELTQANLQKeKETALTELRAMLNGRHAQ-ELALlrsrQQQELELAREQHAREQEEMRLrcsQETAKLKEKLQSEMERN 232
Cdd:TIGR02168  180 KLERTRENLDR-LEDILNELERQLKSLERQaEKAE----RYKELKAELRELELALLVLRL---EELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  233 ARAVESLKRDwESERGLCLENLRRElsakhRSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQL 312
Cdd:TIGR02168  252 EEELEELTAE-LQELEEKLEELRLE-----VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  313 REDLQS-----ERCQYVQDLELRLRDQEVEKQLELESLRASYAELKAQSQE------------------------EIRRL 363
Cdd:TIGR02168  326 EELESKldelaEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEleeqletlrskvaqlelqiaslnnEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  364 WSQLES--PRPDRQDASARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAVERGREDPVLLEQRLQDATEEps 441
Cdd:TIGR02168  406 EARLERleDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE-- 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  442 LESGGIGPSSMREGERREQRVGPSLQPELAENHRCHLTA------------WTSSLEA----QQQAGLVETQESEGEQRE 505
Cdd:TIGR02168  484 LAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvdegYEAAIEAalggRLQAVVVENLNAAKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  506 GLSEGPGQELTQVPVPCAQGTALKVDTEVVARGLGLEAEHRLKLLLLQTELKEEM----------DVLKLENRNLHEKLQ 575
Cdd:TIGR02168  564 FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALsyllggvlvvDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  576 HEVCLKEDLERV------------KHSLVEDHREELKKANERLQLVKQELKDKEAEWKVAsedlkRKAEEELTLMLHDLK 643
Cdd:TIGR02168  644 GYRIVTLDGDLVrpggvitggsakTNSSILERRREIEELEEKIEELEEKIAELEKALAEL-----RKELEELEEELEQLR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  644 EQAEAEKQSV------INKFELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEECPRcghcgQEPAGRVAP 717
Cdd:TIGR02168  719 KELEELSRQIsalrkdLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI-----EELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  718 ADQDWELATRRLRE-DCALQLMQAQSRFLKERKELTEKFTAEQDALLQEAQEKHAcDMRLLQERHQQHVLSLTAQLEARR 796
Cdd:TIGR02168  794 LKEELKALREALDElRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE-ELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953050669  797 RaEVEELKASVESERWALAEARvaELQTEHAAAISALEARHSALLGSLEsrhlsEVQAMREEHRQALEQLRVDLEKQLQ 875
Cdd:TIGR02168  873 S-ELEALLNERASLEEALALLR--SELEELSEELRELESKRSELRRELE-----ELREKLAQLELRLEGLEVRIDNLQE 943
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 2432-2904 1.15e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.78  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2432 EFLQAVQEAFGKEREMlRAELQPRPcgsapGEHSSLLERLEKVVQEQEKSLEHLRaSDRSSLLSEIQALRAQLRmthlQN 2511
Cdd:pfam01576   47 EQLQAETELCAEAEEM-RARLAARK-----QELEEILHELESRLEEEEERSQQLQ-NEKKKMQQHIQDLEEQLD----EE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2512 QEKLQQLCAALTSAEARGSRQEHQL----RRQVELLAYKVEQEKRIaSDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRS 2587
Cdd:pfam01576  116 EAARQKLQLEKVTTEAKIKKLEEDIllleDQNSKLSKERKLLEERI-SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEE 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2588 ELRECKQDNERLLAS--------------LGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEE--AQLQ 2651
Cdd:pfam01576  195 RLKKEEKGRQELEKAkrklegestdlqeqIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIREleAQIS 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2652 HLQREGQSSKTleeLRASLEKQFAQSSQLCVALKHEqtakdnLQKELQIEASRCEaLLAQERGQLSELQRSLEAEKGRSL 2731
Cdd:pfam01576  275 ELQEDLESERA---ARNKAEKQRRDLGEELEALKTE------LEDTLDTTAAQQE-LRSKREQEVTELKKALEEETRSHE 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2732 ELAAALRHERL-----LTEQLSRGPRESPAHHALLRKLKEEKsraAELQARLEQVQrQQEADVQKRRAELEREKEVRAAQ 2806
Cdd:pfam01576  345 AQLQEMRQKHTqaleeLTEQLEQAKRNKANLEKAKQALESEN---AELQAELRTLQ-QAKQDSEHKRKKLEGQLQELQAR 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2807 AREPGRC-LRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVgpgrADAEMRPTGAKEKLRELELQRQRDEHKIRQLQR 2885
Cdd:pfam01576  421 LSESERQrAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDV----SSLESQLQDTQELLQEETRQKLNLSTRLRQLED 496

                          490       500
                   ....*....|....*....|.
gi 1953050669 2886 TVQALEAK--EEAAQRPEAER 2904
Cdd:pfam01576  497 ERNSLQEQleEEEEAKRNVER 517
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2459-2910 1.17e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2459 SAPGEHSSLLERLEkVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSA-----EARGSRQE 2533
Cdd:pfam15921  289 SARSQANSIQSQLE-IIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLAnseltEARTERDQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2534 H-----QLRRQVE-LLA--YKVEQEKRIASDVQKTLTEEQEKAS----SVRKLLVVEQTVVRDLRSELR----ECKQDNE 2597
Cdd:pfam15921  368 FsqesgNLDDQLQkLLAdlHKREKELSLEKEQNKRLWDRDTGNSitidHLRRELDDRNMEVQRLEALLKamksECQGQME 447

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2598 RLLASL---GEAQKEVLQLRSVLDSKESNLRAALQEL--------ESERG----------KERA----------LQSR-- 2644
Cdd:pfam15921  448 RQMAAIqgkNESLEKVSSLTAQLESTKEMLRKVVEELtakkmtleSSERTvsdltaslqeKERAieatnaeitkLRSRvd 527

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2645 LEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKE-------LQIEASRCEALLAQERGQLS 2717
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQLEKEINDRRLELQ 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2718 ELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRE--------SPAHHALLRKLKEEKSRAAELQARLEQVQR------ 2783
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSErlravkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRnfrnks 687

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2784 -QQEADVQKRRAELeREKEVRAAQAREPGRCLR-REGHASQQQAGlepLQAGLAAQEGRKDARRADVgpgRADAEMRPTG 2861
Cdd:pfam15921  688 eEMETTTNKLKMQL-KSAQSELEQTRNTLKSMEgSDGHAMKVAMG---MQKQITAKRGQIDALQSKI---QFLEEAMTNA 760

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1953050669 2862 AKEK--LRElelqrqrDEHKIRQLQRTVQAleAKEEAAQRPEAERLQEERL 2910
Cdd:pfam15921  761 NKEKhfLKE-------EKNKLSQELSTVAT--EKNKMAGELEVLRSQERRL 802
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1230-1734 1.25e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.67  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1230 EKEFscknEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQ 1309
Cdd:PRK03918   199 EKEL----EEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKE 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1310 LQQAAQQQAELKEENsalwsqkeasaaeaeareagtpaPIAHEDSALRREVECLTQEQSEArkqsEKDRAALLSQMKVFE 1389
Cdd:PRK03918   275 IEELEEKVKELKELK-----------------------EKAEEYIKLSEFYEEYLDELREI----EKRLSRLEEEINGIE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1390 AELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRvs 1469
Cdd:PRK03918   328 ERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEE-- 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1470 DEEQLDEEVELLQEKLREKSDGFNEL--------VIKKELAD--RQVMIQE--EEIRRLEETNASCRREAAQLREELERQ 1537
Cdd:PRK03918   406 EISKITARIGELKKEIKELKKAIEELkkakgkcpVCGRELTEehRKELLEEytAELKRIEKELKEIEEKERKLRKELREL 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1538 RdamKALQQDKEALQEKQMSNLLlvSTLQSKLDegrcpvppadscpegpEVQLEAVQRALQQRESevldLKEQLGKMKDD 1617
Cdd:PRK03918   486 E---KVLKKESELIKLKELAEQL--KELEEKLK----------------KYNLEELEKKAEEYEK----LKEKLIKLKGE 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1618 LVSKSDEVLHLNleldaqssraavsvrELQEENASLKAFLQNKEKEImcvsEQLEAQLAGMGSGALREVtydrSSEIEEL 1697
Cdd:PRK03918   541 IKSLKKELEKLE---------------ELKKKLAELEKKLDELEEEL----AELLKELEELGFESVEEL----EERLKEL 597

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 1953050669 1698 RSIIE---NLRENQQRLQKEKaEEMEQLHEVIERLQEELS 1734
Cdd:PRK03918   598 EPFYNeylELKDAEKELEREE-KELKKLEEELDKAFEELA 636
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1644-1877 1.26e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1644 RELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGsgALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLH 1723
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIA--ALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1724 EVIERLQEELSLGAPAVPAAVDcelpavpapavGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAEL 1803
Cdd:COG4942    108 ELLRALYRLGRQPPLALLLSPE-----------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953050669 1804 ERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAA 1877
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2463-2907 1.27e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2463 EHSSLLERLEKVVQEQEKSLEHLRA--SDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQV 2540
Cdd:PRK02224   245 EHEERREELETLEAEIEDLRETIAEteREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2541 ELLAYKVEQEKRI-------------ASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQ 2607
Cdd:PRK02224   325 ELRDRLEECRVAAqahneeaeslredADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAP 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2608 KEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAqlQHLQREG----------------------QSSKTLEE 2665
Cdd:PRK02224   405 VDLGNAEDFLEELREERDELREREAELEATLRTARERVEEA--EALLEAGkcpecgqpvegsphvetieedrERVEELEA 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2666 LRASLEKQFAQSSQLCVALKHEQTAKDNLQKeLQIEASRCEALLAQERGQLSELQRSLEAEKGRSLEL-AAALRHERLLT 2744
Cdd:PRK02224   483 ELEDLEEEVEEVEERLERAEDLVEAEDRIER-LEERREDLEELIAERRETIEEKRERAEELRERAAELeAEAEEKREAAA 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2745 EQLSRGPRESPAHHALLRKLKEEKSR------AAELQARLEQVQRQQEADVQKR--RAELEREKEVRAAQAREPGRCLR- 2815
Cdd:PRK02224   562 EAEEEAEEAREEVAELNSKLAELKERieslerIRTLLAAIADAEDEIERLREKReaLAELNDERRERLAEKRERKRELEa 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2816 --REGHASQQQAGLEPLQAGLAAQEGRKDARRADvgpgRADAEMRPTGAKEKLRELElqRQRDEHKirQLQRTVQALEAK 2893
Cdd:PRK02224   642 efDEARIEEAREDKERAEEYLEQVEEKLDELREE----RDDLQAEIGAVENELEELE--ELRERRE--ALENRVEALEAL 713

                          490
                   ....*....|....
gi 1953050669 2894 EEaaqrpEAERLQE 2907
Cdd:PRK02224   714 YD-----EAEELES 722
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2471-2745 1.28e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 1.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2471 LEKVVQEQEKSLEHLRasdrsSLLSEIQALRAQLRMTHLQNQEKLQQLcaaltsaeaRGSRQEHQ-LRRQVELLAYKVEQ 2549
Cdd:TIGR04523  372 IEKLKKENQSYKQEIK-----NLESQINDLESKIQNQEKLNQQKDEQI---------KKLQQEKElLEKEIERLKETIIK 437

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2550 EKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQ 2629
Cdd:TIGR04523  438 NNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTK 517

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2630 ELESERGKERALQSRLEEAQLQHLQREGQSSKTLEEL-RASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEAL 2708
Cdd:TIGR04523  518 KISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELkKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKE 597

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1953050669 2709 LAQERGQLSELQRSLEaEKGRSLELAAAlRHERLLTE 2745
Cdd:TIGR04523  598 KKDLIKEIEEKEKKIS-SLEKELEKAKK-ENEKLSSI 632
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 184-877 1.41e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.57  E-value: 1.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  184 ELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAVESLKRDWESErglclENLRRELsakhr 263
Cdd:TIGR00618  180 QLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSH-----AYLTQKR----- 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  264 sELENLQDQFKRELSEQKAELEKifqaknqaecaLRTLEAQHEEALRQLREDLQSERCQYVQDLELRLRDQEVEKQLELE 343
Cdd:TIGR00618  250 -EAQEEQLKKQQLLKQLRARIEE-----------LRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  344 SLRASYAELKAQSQEeirrlwSQLESPRPDRQDASARTPHGEELEQRERecgvQQQRRGRRAEQESELgqSPEGAVERGR 423
Cdd:TIGR00618  318 SKMRSRAKLLMKRAA------HVKQQSSIEEQRRLLQTLHSQEIHIRDA----HEVATSIREISCQQH--TLTQHIHTLQ 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  424 EDPVLLEQRLQDATEEPSL---ESGGIGPSSMREGERREQRVGPSLQPELAENHRCHLTAWTSSLEAQQQAGLVETQESE 500
Cdd:TIGR00618  386 QQKTTLTQKLQSLCKELDIlqrEQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESA 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  501 GEQREGLsegpgQELTQVPVPCAQGTALKvdTEVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLE--NRNLHEKLQHEV 578
Cdd:TIGR00618  466 QSLKERE-----QQLQTKEQIHLQETRKK--AVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGplTRRMQRGEQTYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  579 CLKEDLERVKHSLVEDhREELKKANERLQLVKQELKDKEAEWKVASEDLKrKAEEELTLMLHDLKEQAEAEKQsvinKFE 658
Cdd:TIGR00618  539 QLETSEEDVYHQLTSE-RKQRASLKEQMQEIQQSFSILTQCDNRSKEDIP-NLQNITVRLQDLTEKLSEAEDM----LAC 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  659 LREIKMRQLQDQQAAQILDLEGSLVEQqgRLRQLEHGLEAEEcprcghcgqepagrVAPADQDWELATRRLREDCALQLM 738
Cdd:TIGR00618  613 EQHALLRKLQPEQDLQDVRLHLQQCSQ--ELALKLTALHALQ--------------LTLTQERVREHALSIRVLPKELLA 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  739 QAQSRFLKERKELTE----KFTAEQDALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEVEELKASVESERWAL 814
Cdd:TIGR00618  677 SRQLALQKMQSEKEQltywKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVL 756

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1953050669  815 AEARVAELQTEHAAAIsalearhsALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEK 877
Cdd:TIGR00618  757 KARTEAHFNNNEEVTA--------ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQE 811
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 1352-1629 1.48e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 44.46  E-value: 1.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1352 EDSALRREVECLTQEQSEARKQSEKDRAALLSQM-KVFEAELEEQLSRHEACAKQAEELSALRQQMAALDkhlrSQRQFM 1430
Cdd:PLN03229   430 PVRELEGEVEKLKEQILKAKESSSKPSELALNEMiEKLKKEIDLEYTEAVIAMGLQERLENLREEFSKAN----SQDQLM 505

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1431 DEQAVER-EHEREEFQREIQRLE---------EQLRQAARPRPHGPRVSDEEQLDEEVE------LLQEKLREKSDGFNE 1494
Cdd:PLN03229   506 HPVLMEKiEKLKDEFNKRLSRAPnylslkyklDMLNEFSRAKALSEKKSKAEKLKAEINkkfkevMDRPEIKEKMEALKA 585

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1495 LVIKKELADRQVMiQEEEIRRLEETNASCRREAAQLREELERQRDAMKA-------------LQQDKEALQE---KQMSN 1558
Cdd:PLN03229   586 EVASSGASSGDEL-DDDLKEKVEKMKKEIELELAGVLKSMGLEVIGVTKknkdtaeqtpppnLQEKIESLNEeinKKIER 664

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953050669 1559 LLLVSTLQSKLDEGRCPVPPADSCPEGPEVQ-LEAVQRALQQRESEVLD---LKEQLGKMKDDLVSKSDEVLHLN 1629
Cdd:PLN03229   665 VIRSSDLKSKIELLKLEVAKASKTPDVTEKEkIEALEQQIKQKIAEALNsseLKEKFEELEAELAAARETAAESN 739
PTZ00121 PTZ00121
MAEBL; Provisional
 2439-2671 1.59e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 1.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2439 EAFGKEREMLRAELQPRpcgsAPGEHSSLLERLEKVVQEQEKSLEHLRASDRSSLLSEIQALR----AQLRMTHLQNQEK 2514
Cdd:PTZ00121  1555 EELKKAEEKKKAEEAKK----AEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKkaeeAKIKAEELKKAEE 1630

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2515 LQQLCAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRIASdvqktltEEQEKASSVRKLLVVEQTVVRDLRSELREcKQ 2594
Cdd:PTZ00121  1631 EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE-------EDKKKAEEAKKAEEDEKKAAEALKKEAEE-AK 1702

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2595 DNERLLASLGEAQKEVLQLRSvlDSKESNLRAALQELESERGKERALQSRLEEAQ---LQHLQREGQssKTLEELRASLE 2671
Cdd:PTZ00121  1703 KAEELKKKEAEEKKKAEELKK--AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEkkkIAHLKKEEE--KKAEEIRKEKE 1778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2820-3016 1.71e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2820 ASQQQAGLEPLQAGLAAQEGRKD---ARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEA 2896
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAalkKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2897 AQRPEAERLQE-ERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNEKAVTSLLHTLEELKSELSTPSSSQKKMTA 2975
Cdd:COG4942    102 QKEELAELLRAlYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1953050669 2976 ELQTQLVDvLLKDNDSLTKALRTVTQEKAELCRAVSQLEKS 3016
Cdd:COG4942    182 ELEEERAA-LEALKAERQKLLARLEKELAELAAELAELQQE 221
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2697-2981 1.80e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 1.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2697 ELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRK----LKEEKSRAA 2772
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAeveqLEERIAQLS 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2773 ELQARLEQVQRQQEADVQKRRAELEREKEVRAAQARepgrclRREGHASQQQAGLEPLQAgLAAQEGRKDARRADVGPGR 2852
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEA------QIEQLKEELKALREALDE-LRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2853 ADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRpEAERLQEERLGLERVRQQLLCAAglltsfisR 2932
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELES-ELEALLNERASLEEALALLRSEL--------E 897

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1953050669 2933 TVDRTISDWtssnEKAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQL 2981
Cdd:TIGR02168  898 ELSEELREL----ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 251-319 2.27e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 43.66  E-value: 2.27e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953050669  251 LENLRRELSAKHRsELENL---QDQFKRELSEQKAELEKIFQ-----AKNQAECALRTLEAQHEEALRQLREDLQSE 319
Cdd:PRK00409   525 LEELERELEQKAE-EAEALlkeAEKLKEELEEKKEKLQEEEDklleeAEKEAQQAIKEAKKEADEIIKELRQLQKGG 600
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 2577-2907 2.34e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.81  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2577 VEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEE---AQLQHL 2653
Cdd:pfam02463  153 ERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEeylLYLDYL 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2654 QREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKElqieasrceallaqergqLSELQRSLEAEKGRSLEL 2733
Cdd:pfam02463  233 KLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKE------------------EEKEKKLQEEELKLLAKE 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2734 AAALRHERLLTEQLsrgprespaHHALLRKLKEEKSRAAELQARLEQVQRQQEAdvqkRRAELEREKEVRAAQAREPGRC 2813
Cdd:pfam02463  295 EEELKSELLKLERR---------KVDDEEKLKESEKEKKKAEKELKKEKEEIEE----LEKELKELEIKREAEEEEEEEL 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2814 LRREGHASQQQAGLEPLQAGLAAQEGRKDARRadvgpgradaemrptGAKEKLRELELQRQRDEHKIRQLQRTVQALEAK 2893
Cdd:pfam02463  362 EKLQEKLEQLEEELLAKKKLESERLSSAAKLK---------------EEELELKSEEEKEAQLLLELARQLEDLLKEEKK 426

                          330
                   ....*....|....
gi 1953050669 2894 EEAAQRPEAERLQE 2907
Cdd:pfam02463  427 EELEILEEEEESIE 440
PRK10361 PRK10361
DNA recombination protein RmuC; Provisional
 1370-1535 2.45e-03

DNA recombination protein RmuC; Provisional


Pssm-ID: 182409 [Multi-domain]  Cd Length: 475  Bit Score: 43.43  E-value: 2.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1370 ARKQSEKDRAALLSQMKVFEAEL---EEQLSRHEACAKQAE----ELSALRQQMAALDKHLRSQRQFMDEQAVEREHERE 1442
Cdd:PRK10361    23 ASYQHAQQKAEQLAEREEMVAELsaaKQQITQSEHWRAECEllnnEVRSLQSINTSLEADLREVTTRMEAAQQHADDKIR 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1443 EFQREIQRLEEQLRQAA-RPRPHGPRVSDeEQLDEEVELLQEKLREKSDGFNELV---IKKELADRQVMIQeeEIRRLEE 1518
Cdd:PRK10361   103 QMINSEQRLSEQFENLAnRIFEHSNRRVD-EQNRQSLNSLLSPLREQLDGFRRQVqdsFGKEAQERHTLAH--EIRNLQQ 179

                          170
                   ....*....|....*..
gi 1953050669 1519 TNASCRREAAQLREELE 1535
Cdd:PRK10361   180 LNAQMAQEAINLTRALK 196
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1252-1466 2.65e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1252 ERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQK 1331
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1332 EASAAEAEAR--------EAGTPAPIAHEDSALR-----REVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSR 1398
Cdd:COG4942    100 EAQKEELAELlralyrlgRQPPLALLLSPEDFLDavrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953050669 1399 HEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGP 1466
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1441-1621 2.75e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 2.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1441 REEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLR--EKSDGFNELVIKKELADRQVMIQEEEIRRLEE 1518
Cdd:COG4913    612 LAALEAELAELEEELAEAEE---------RLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAELERLDA 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1519 TN----------ASCRREAAQLREELERQRDAMKALQQDKEALQEkqmsnllLVSTLQSKLDEgrcpvpPADSCPEGPEV 1588
Cdd:COG4913    683 SSddlaaleeqlEELEAELEELEEELDELKGEIGRLEKELEQAEE-------ELDELQDRLEA------AEDLARLELRA 749

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1953050669 1589 QLEAVQRALQQRESEvLDLKEQLGKMKDDLVSK 1621
Cdd:COG4913    750 LLEERFAAALGDAVE-RELRENLEERIDALRAR 781
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1248-1735 2.79e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 2.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1248 QQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSAL 1327
Cdd:TIGR00618  180 QLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQ 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1328 WSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQsEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAE 1407
Cdd:TIGR00618  260 QLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHI-KAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQS 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1408 ELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREE---------FQREIQRLEEQLRQAArprphgprvSDEEQLDEEV 1478
Cdd:TIGR00618  339 SIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQhtltqhihtLQQQKTTLTQKLQSLC---------KELDILQREQ 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1479 ELLQEKLREksdgFNELVIKKELADRQVMIQEEEIRRLE---ETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQ 1555
Cdd:TIGR00618  410 ATIDTRTSA----FRDLQGQLAHAKKQQELQQRYAELCAaaiTCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1556 MSNLLLVSTLQSKLDEGRCPVPPADSCPEgPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQ 1635
Cdd:TIGR00618  486 TRKKAVVLARLLELQEEPCPLCGSCIHPN-PARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1636 SSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAG--MGSGALREVTYDRSSEIEELRsIIENLRENQQRLQK 1713
Cdd:TIGR00618  565 MQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAedMLACEQHALLRKLQPEQDLQD-VRLHLQQCSQELAL 643

                          490       500
                   ....*....|....*....|..
gi 1953050669 1714 EKAEEMEQLHEVIERLQEELSL 1735
Cdd:TIGR00618  644 KLTALHALQLTLTQERVREHAL 665
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2463-2801 2.89e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 2.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2463 EHSSLLERLEKVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVEL 2542
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2543 -----------LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVL 2611
Cdd:COG1196    523 agavavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD 602

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2612 QLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAK 2691
Cdd:COG1196    603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2692 DNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRA 2771
Cdd:COG1196    683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1953050669 2772 AELQARLEQVQRQQEA-------------DVQKRRAELEREKE 2801
Cdd:COG1196    763 EELERELERLEREIEAlgpvnllaieeyeELEERYDFLSEQRE 805
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
164-396 2.95e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 2.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  164 KEKETALTELRAMLNG--RHAQELALLRSR--QQQELELAREQHAREQEEmRLRCSQETAKLKEKLQSEMERNARAVESL 239
Cdd:PRK03918   210 NEISSELPELREELEKleKEVKELEELKEEieELEKELESLEGSKRKLEE-KIRELEERIEELKKEIEELEEKVKELKEL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  240 KrdWESERGLCLENLRRELS----------AKHRSELENLQDQFKrELSEQKAELEKIFQAKNQAECALRTLEAQHE--E 307
Cdd:PRK03918   289 K--EKAEEYIKLSEFYEEYLdelreiekrlSRLEEEINGIEERIK-ELEEKEERLEELKKKLKELEKRLEELEERHElyE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  308 ALRQLREDLQSercqyvqdLELRLRDQEVEK-QLELESLRASYAELKaQSQEEIRRLWSQLESPRPDRQDASartphgEE 386
Cdd:PRK03918   366 EAKAKKEELER--------LKKRLTGLTPEKlEKELEELEKAKEEIE-EEISKITARIGELKKEIKELKKAI------EE 430

                          250
                   ....*....|
gi 1953050669  387 LEQRERECGV 396
Cdd:PRK03918   431 LKKAKGKCPV 440
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1689-1960 3.42e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 3.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1689 DRSSEIEELRSIIENLRENQQRLQKEKAE---EMEQLHEVIERLQEELSlgapavpaavdcelpavpapAVGPEALAAAG 1765
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAEleaELEELRLELEELELELE--------------------EAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1766 AASRLFAEQEHRHG--QALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEID 1843
Cdd:COG1196    296 ELARLEQDIARLEErrRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1844 AMKRQKLAHSAELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRLSRQLQVLNQRFLRCQKEADKQQARGARLR 1923
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1953050669 1924 pRGARGLQGPGPRAEEASRDEASQQDVDSRQVASATQ 1960
Cdd:COG1196    456 -EEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1207-1546 3.61e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.40  E-value: 3.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1207 GLLELALDSTRQLEEARQIHSRFEKEFscknEETAQVVRKQQQLLERLEEE-NAARTRL--MLELHQAQGIIEGFKEEKA 1283
Cdd:COG3096    282 ELSERALELRRELFGARRQLAEEQYRL----VEMARELEELSARESDLEQDyQAASDHLnlVQTALRQQEKIERYQEDLE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1284 SLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKeenSALWSQKEASAAEAEAREAGTPAPIAHEDSALRREVECL 1363
Cdd:COG3096    358 ELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLK---SQLADYQQALDVQQTRAIQYQQAVQALEKARALCGLPDL 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1364 TQEQSEARKQSEKDRAALLSQMKVfeaELEEQLSRHEACAKQAEELSALRQQMAAldkhlrsqrqfmdeqAVEREHEREE 1443
Cdd:COG3096    435 TPENAEDYLAAFRAKEQQATEEVL---ELEQKLSVADAARRQFEKAYELVCKIAG---------------EVERSQAWQT 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1444 FQREIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASC 1523
Cdd:COG3096    497 ARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEA 576

                          330       340
                   ....*....|....*....|...
gi 1953050669 1524 RREAAQLREELERQRDAMKALQQ 1546
Cdd:COG3096    577 VEQRSELRQQLEQLRARIKELAA 599
COG3903 COG3903
Predicted ATPase [General function prediction only];
2585-2926 3.70e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 43.08  E-value: 3.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2585 LRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLE 2664
Cdd:COG3903    557 LRGLLREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAA 636

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2665 ELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLT 2744
Cdd:COG3903    637 AAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAA 716

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2745 EQLSRGPRESPAHHALLRkLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQQQ 2824
Cdd:COG3903    717 AAAAAAAAAALLAAAAAA-ALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAA 795

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2825 AGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAER 2904
Cdd:COG3903    796 AAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAA 875

                          330       340
                   ....*....|....*....|..
gi 1953050669 2905 LQEERLGLERVRQQLLCAAGLL 2926
Cdd:COG3903    876 AAAAAAAALLAAAAAAAAAAAA 897
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2587-2852 3.78e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 3.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2587 SELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQlqhlQREGQSSKTLEEL 2666
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALE----AELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2667 RASLEKQFAQSSQLCVALkheqtAKDNLQKELQIEASRCEALLAQERGQLseLQRSLEAEKGRSLELAAALRHERLLTEQ 2746
Cdd:COG4942     96 RAELEAQKEELAELLRAL-----YRLGRQPPLALLLSPEDFLDAVRRLQY--LKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2747 LSrgprespahhALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREpgrclrreghASQQQAG 2826
Cdd:COG4942    169 LE----------AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE----------AEELEAL 228

                          250       260
                   ....*....|....*....|....*.
gi 1953050669 2827 LEPLQAGLAAQEGRKDARRADVGPGR 2852
Cdd:COG4942    229 IARLEAEAAAAAERTPAAGFAALKGK 254
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2755-2914 3.95e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 3.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2755 PAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELERE-------KEVRAAQAREPGRCLRREGHASQQQAG- 2826
Cdd:COG4913    258 RELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAelarleaELERLEARLDALREELDELEAQIRGNGg 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2827 --LEPLQAGLAAQEGRKDARRADVGpgRADAEMRPTGAKEKLRELELQRQRDEHK---------IRQLQRTVQALEAKEE 2895
Cdd:COG4913    338 drLEQLEREIERLERELEERERRRA--RLEALLAALGLPLPASAEEFAALRAEAAallealeeeLEALEEALAEAEAALR 415

                          170
                   ....*....|....*....
gi 1953050669 2896 AAQRpEAERLQEERLGLER 2914
Cdd:COG4913    416 DLRR-ELRELEAEIASLER 433
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1217-1553 4.00e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.13  E-value: 4.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1217 RQLEEARQIHSRFEKefsCKNEETAQVVRKQQQLLERLEEenaARTRLMLELHQAQGIIEGFKEEKASLQEAL------- 1289
Cdd:PRK03918   362 ELYEEAKAKKEELER---LKKRLTGLTPEKLEKELEELEK---AKEEIEEEISKITARIGELKKEIKELKKAIeelkkak 435

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1290 -----CRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEareagtpapiahEDSALRREVECLT 1364
Cdd:PRK03918   436 gkcpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLK------------KESELIKLKELAE 503

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1365 QEQSEARKQSEKDRAALLSQMKVFEaELEEQL----SRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEqaVEREHE 1440
Cdd:PRK03918   504 QLKELEEKLKKYNLEELEKKAEEYE-KLKEKLiklkGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAE--LLKELE 580

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1441 R------EEFQREIQRLEEQLRQAARPRPhgpRVSDEEQLDEEVELLQEKLREKSDGFNELV-----IKKELADRQVMIQ 1509
Cdd:PRK03918   581 ElgfesvEELEERLKELEPFYNEYLELKD---AEKELEREEKELKKLEEELDKAFEELAETEkrleeLRKELEELEKKYS 657

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1953050669 1510 EEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQE 1553
Cdd:PRK03918   658 EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE 701
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1345-1458 4.11e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 43.02  E-value: 4.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1345 TPAPIAHEDSALRREVECLTQeQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEA-CAKQAEELSALRQQMAALDKHL 1423
Cdd:PRK11448   136 PPEDPENLLHALQQEVLTLKQ-QLELQAREKAQSQALAEAQQQELVALEGLAAELEEkQQELEAQLEQLQEKAAETSQER 214

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1953050669 1424 RSQRQFMDEQAVEREHEREEFQREIqrLEEQLRQA 1458
Cdd:PRK11448   215 KQKRKEITDQAAKRLELSEEETRIL--IDQQLRKA 247
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1407-1732 4.41e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.57  E-value: 4.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1407 EELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQaarprphgprvsdeeqLDEEVELLQEKLR 1486
Cdd:pfam07888   41 QERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQ----------------SREKHEELEEKYK 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1487 EKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREELERQRD-AMKALQQDKEALQEKQmsnlllvsTL 1565
Cdd:pfam07888  105 ELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKErAKKAGAQRKEEEAERK--------QL 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1566 QSKLDEGRCPVPPADScpegpevQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNL---------ELDAQS 1636
Cdd:pfam07888  177 QAKLQQTEEELRSLSK-------EFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEAlleelrslqERLNAS 249

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1637 SRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMgSGALREvtyDRSSEIEELRSIIENLRENQQRLQKEKA 1716
Cdd:pfam07888  250 ERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADA-SLALRE---GRARWAQERETLQQSAEADKDRIEKLSA 325

                          330
                   ....*....|....*.
gi 1953050669 1717 EemeqLHEVIERLQEE 1732
Cdd:pfam07888  326 E----LQRLEERLQEE 337
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
224-635 4.54e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 42.72  E-value: 4.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  224 KLQSEMER--NAR-AVESLKRDWESErglcLENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRT 300
Cdd:PRK02224   163 KLEEYRERasDARlGVERVLSDQRGS----LDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  301 LE---AQHEEALRQLrEDLQSErcqyVQDLELRLRDQEVEKQL---ELESLRASYAELkaqsQEEIRRLWSQLESPRPDR 374
Cdd:PRK02224   239 ADevlEEHEERREEL-ETLEAE----IEDLRETIAETEREREElaeEVRDLRERLEEL----EEERDDLLAEAGLDDADA 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  375 QDASAR----TPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAVERGREDPVLLEQRLQDATEEPSLESGGIGPS 450
Cdd:PRK02224   310 EAVEARreelEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEEL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  451 SMREGERREQRVGPSLQPELAENHRCHLTAWTSSL---EAQQQAGLVETQESEGEQREGLSEGP----GQELTQVPVPCa 523
Cdd:PRK02224   390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELrerEAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVE- 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  524 qgtALKVDTEVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRnlHEKLQHEVCLKEDLERVKHSLVEDHREELKKAN 603
Cdd:PRK02224   469 ---TIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR--IERLEERREDLEELIAERRETIEEKRERAEELR 543

                          410       420       430
                   ....*....|....*....|....*....|..
gi 1953050669  604 ERlqlvKQELKDKEAEWKVASEDLKRKAEEEL 635
Cdd:PRK02224   544 ER----AAELEAEAEEKREAAAEAEEEAEEAR 571
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
217-416 5.09e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 5.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  217 ETAKLKEKLQSEMERNARAVESLKRDwESERGLCLENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAEC 296
Cdd:COG4913    245 EDAREQIELLEPIRELAERYAAARER-LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALRE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  297 ALRTLEAQHEEALRQLREDLQSERCQYVQDLELRLRD-QEVEKQ-----LELESLRASYAELKAQSQEEIRRLWSQLESP 370
Cdd:COG4913    324 ELDELEAQIRGNGGDRLEQLEREIERLERELEERERRrARLEALlaalgLPLPASAEEFAALRAEAAALLEALEEELEAL 403

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1953050669  371 RPDRQDASAR-TPHGEELEQRERECGVQQQRRGR--------RAEQESELGQSPE 416
Cdd:COG4913    404 EEALAEAEAAlRDLRRELRELEAEIASLERRKSNiparllalRDALAEALGLDEA 458
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 2627-2908 6.62e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 6.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2627 ALQELESERGKERALQSRL---EEAQLQHLQREGQSSKTLEELRASLEKQFA-QSSQLCVALKHEQTAKDNLQKELQIEA 2702
Cdd:pfam17380  283 AVSERQQQEKFEKMEQERLrqeKEEKAREVERRRKLEEAEKARQAEMDRQAAiYAEQERMAMERERELERIRQEERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2703 SRC-EALLAQERGQLSELQRsLEAEKGRSLELA----AALRHERLLTEQLSRGPRESP------------AHHALLRKLK 2765
Cdd:pfam17380  363 ERIrQEEIAMEISRMRELER-LQMERQQKNERVrqelEAARKVKILEEERQRKIQQQKvemeqiraeqeeARQREVRRLE 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2766 EEKSRAAEL-----QARLEQVQ--RQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQQQAGLEPLQAGLAAQE 2838
Cdd:pfam17380  442 EERAREMERvrleeQERQQQVErlRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKE 521

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953050669 2839 grKDARRADVgpgrADAEMRPTGAKEKLRELEL-QRQRDEHKIRQLQRTVQALEA----KEEAAQRPEAERLQEE 2908
Cdd:pfam17380  522 --MEERQKAI----YEEERRREAEEERRKQQEMeERRRIQEQMRKATEERSRLEAmereREMMRQIVESEKARAE 590
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 593-843 6.74e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 6.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  593 EDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRkaeeeltlmlhdlKEQAEAEKQSVINKFELREIKMRQLQDQQA 672
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA-------------LERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  673 AQILDLEGSLVEQQGRLRQLEHGLEAEecprcghcGQEPAGRVAPADQDWELATRRlredcaLQLMQAQSRFLKERKELT 752
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRL--------GRQPPLALLLSPEDFLDAVRR------LQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  753 EKFTAEQDALLQEAQEKHACDMRLLQERHQQHvlSLTAQLEARRRAEVEELKASVESERWALAE--ARVAELQTEHAAAI 830
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEER--AALEALKAERQKLLARLEKELAELAAELAElqQEAEELEALIARLE 233

                          250
                   ....*....|...
gi 1953050669  831 SALEARHSALLGS 843
Cdd:COG4942    234 AEAAAAAERTPAA 246
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 797-1458 7.37e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 7.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  797 RAEVEELKASVESERWALAEARVAELQTEHAAAISALEArhsallgslESRHLSEVQAMREEHRQALEQLRVDLEKQLQE 876
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEE---------LEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  877 KEAshptpltqalekhplsHGQELPPVEGGLRtqtssgqlegvkapvpPEVQGAQQegapvpAEVEAQRpaLLAELRQET 956
Cdd:COG1196    290 EYE----------------LLAELARLEQDIA----------------RLEERRRE------LEERLEE--LEEELAELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  957 GKQQLHCQEEPEVLEcpsepflEQQILQPKgefESEKKVALHEKEihglecaQAQSLYQKEKESLFLQLQEKNNQILQLK 1036
Cdd:COG1196    330 EELEELEEELEELEE-------ELEEAEEE---LEEAEAELAEAE-------EALLEAEAELAEAEEELEELAEELLEAL 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1037 EQILSLSHEVEERRRDLEQLQQRRERENQEGTNLISMLKSDADLSDRERRALRDALRRLLSLFGEMLKVAIALKSRISER 1116
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1117 VGLCLEDED----------------PPGAWPSGQALSAAPVLEETWPGSEAALLELDRSLPECVEMPSEAEISSHICESF 1180
Cdd:COG1196    473 ALLEAALAElleelaeaaarlllllEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1181 FMSPESSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAA 1260
Cdd:COG1196    553 VEDDEVAAAAIEYLKA----AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1261 RTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEA 1340
Cdd:COG1196    629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1341 reagtpapIAHEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQ----- 1415
Cdd:COG1196    709 --------LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREiealg 780

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 1953050669 1416 ---MAALD--KHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQA 1458
Cdd:COG1196    781 pvnLLAIEeyEELEERYDFLSEQREDLEEARETLEEAIEEIDRETRER 828
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 146-393 7.95e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.03  E-value: 7.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  146 SLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQeLALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEK- 224
Cdd:pfam15921  209 SMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQ-LEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKa 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  225 ---------LQSEME---RNARAVESLKRDWESERGLCLENLRRELSAKHRS---ELENLQDQF---KRELSEQKAELEK 286
Cdd:pfam15921  288 ssarsqansIQSQLEiiqEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMyedKIEELEKQLvlaNSELTEARTERDQ 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669  287 IFQAKNQAECALRTLEAQHEEALRQLreDLQSERCQYVQDLEL-------RLRDQEVEKQLELESLRASYAELKAQSQEE 359
Cdd:pfam15921  368 FSQESGNLDDQLQKLLADLHKREKEL--SLEKEQNKRLWDRDTgnsitidHLRRELDDRNMEVQRLEALLKAMKSECQGQ 445

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1953050669  360 IRRLWSQLESPRPDRQDASARTPHGEELEQRERE 393
Cdd:pfam15921  446 MERQMAAIQGKNESLEKVSSLTAQLESTKEMLRK 479
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1432-1684 8.22e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 8.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1432 EQAVEREHEREEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREKSDGFNELvikkelaDRQVMIQEE 1511
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKK---------EEKALLKQLAALERRIAALARRIRAL-------EQELAALEA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1512 EIRRLEETNASCRREAAQLREELERQ---------RDAMKALQQDKEALQEKQMSNLL---------LVSTLQSKLDEgr 1573
Cdd:COG4942     84 ELAELEKEIAELRAELEAQKEELAELlralyrlgrQPPLALLLSPEDFLDAVRRLQYLkylaparreQAEELRADLAE-- 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1574 cpvppadscpegpevqLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASL 1653
Cdd:COG4942    162 ----------------LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL 225

                          250       260       270
                   ....*....|....*....|....*....|.
gi 1953050669 1654 KAFLQNKEKEIMCVSEQLEAQLAGMGSGALR 1684
Cdd:COG4942    226 EALIARLEAEAAAAAERTPAAGFAALKGKLP 256
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2621-2919 8.63e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 8.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2621 ESNLRAALQELESERGKERALQSRLEEA--QLQHLQREGQSSKTLEELRASLEkqfaqssqlcvalKHEQTAKDNLQKEL 2698
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKrqQLERLRREREKAERYQALLKEKR-------------EYEGYELLKEKEAL 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2699 QIEASRCEALLAQERGQLSELQRSLEAekgRSLELAAALRHERLLTEQLSRGPRESPAhhALLRKLKEEKSRAAELQARL 2778
Cdd:TIGR02169  236 ERQKEAIERQLASLEEELEKLTEEISE---LEKRLEEIEQLLEELNKKIKDLGEEEQL--RVKEKIGELEAEIASLERSI 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2779 EQVQRQQEaDVQKRRAELEREKEVRAAQAREPGRCLRreghasQQQAGLEPLQAGLAAQEGRKDARRADVGPGRAD-AEM 2857
Cdd:TIGR02169  311 AEKERELE-DAEERLAKLEAEIDKLLAEIEELEREIE------EERKRRDKLTEEYAELKEELEDLRAELEEVDKEfAET 383

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953050669 2858 RPTGAKEKLRELELQRQRDEHK--IRQLQRTVQALEAKEEAAqRPEAERLQEERLGLERVRQQL 2919
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKreLDRLQEELQRLSEELADL-NAAIAGIEAKINELEEEKEDK 446
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1371-1519 8.84e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.77  E-value: 8.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1371 RKQSEKDRAALLSQMKVFEAELEEQLSRHEacakqaEELSALRQQMAALDKHLRsqrqfmdeqavEREHEREEFQREIQR 1450
Cdd:COG2433    383 EELIEKELPEEEPEAEREKEHEERELTEEE------EEIRRLEEQVERLEAEVE-----------ELEAELEEKDERIER 445

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 1451 LEEQLRQAARPRPHGPRVSDE-EQLDEEVELLQEKLREKSDGFNEL---------VIKKELADRQVMIQE------EEIR 1514
Cdd:COG2433    446 LERELSEARSEERREIRKDREiSRLDREIERLERELEEERERIEELkrklerlkeLWKLEHSGELVPVKVvekftkEAIR 525


                   ....*
gi 1953050669 1515 RLEET 1519
Cdd:COG2433    526 RLEEE 530
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2466-3018 9.23e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 9.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2466 SLLERLEKVVQEQEKSLEHLRA---SDRSSLLSEIQALRAQLRmthlQNQEKLQQLCAALTSAEARgsrqEHQLRRQVEL 2542
Cdd:TIGR02169  304 ASLERSIAEKERELEDAEERLAkleAEIDKLLAEIEELEREIE----EERKRRDKLTEEYAELKEE----LEDLRAELEE 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2543 LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLR-------- 2614
Cdd:TIGR02169  376 VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAleikkqew 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2615 ---------SVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALK 2685
Cdd:TIGR02169  456 kleqlaadlSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGE 535

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2686 HEQTA--------KDNLQKELQIEASRCEALLAQERG-----------QLSELQRSLEAEKG------------------ 2728
Cdd:TIGR02169  536 RYATAievaagnrLNNVVVEDDAVAKEAIELLKRRKAgratflplnkmRDERRDLSILSEDGvigfavdlvefdpkyepa 615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2729 -----------RSLELAAALRHE-RLLT---EQLSRGPRESPAHHALLRKL---KEEKSRAAELQARLEQVQRqQEADVQ 2790
Cdd:TIGR02169  616 fkyvfgdtlvvEDIEAARRLMGKyRMVTlegELFEKSGAMTGGSRAPRGGIlfsRSEPAELQRLRERLEGLKR-ELSSLQ 694

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2791 KRRAELEREKEVRAAQAREPGRCLRR--------EGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRAD-AEMRPTG 2861
Cdd:TIGR02169  695 SELRRIENRLDELSQELSDASRKIGEiekeieqlEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARiEELEEDL 774

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2862 AKEKLRELELQRQRDEHKIRQLQRTVQALEAK----EEAAQRPEAE--RLQEERLGLERVRQQLLCAAGLLTSFIsrtvd 2935
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSRIPEIQAELSKLEEEvsriEARLREIEQKlnRLTLEKEYLEKEIQELQEQRIDLKEQI----- 849

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953050669 2936 rtisdwtSSNEKAVTSLLHTLEELKSELstpsSSQKKMTAELQTQLVDvLLKDNDSLTKALRTVTQEKAELCRAVSQLEK 3015
Cdd:TIGR02169  850 -------KSIEKEIENLNGKKEELEEEL----EELEAALRDLESRLGD-LKKERDELEAQLRELERKIEELEAQIEKKRK 917


                   ...
gi 1953050669 3016 SLK 3018
Cdd:TIGR02169  918 RLS 920
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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