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Conserved domains on  [gi|1953366519|ref|XP_038299670|]
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pericentrin isoform X3 [Canis lupus familiaris]

Protein Classification

kinesin family protein( domain architecture ID 13278080)

kinesin family protein is a microtubule-dependent molecular motor that plays an important role in intracellular transport and in cell division and has ATPase-containing motor domain; similar to N-type kinesins that are (+) end-directed motors and have a N-terminal motor domain: may have a coiled-coil segment C-terminal to the motor domain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3069-3147 7.13e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


:

Pssm-ID: 463115  Cd Length: 77  Bit Score: 103.06  E-value: 7.13e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366519 3069 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAdkkTTTSRPFTRFRTAVRVVIAILRLRFLVKKW 3147
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD---RPSRKPRRKLKSAALAVIAIARMKRLAREW 77
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2461-3017 5.25e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 5.25e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2461 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAQlRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVELLAYKV 2540
Cdd:COG1196    188 LERLEDILGELERQLEPL----------ERQAEKAE-RYRELKEELKELEAELLLLKLRELEAELE-ELEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2541 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAA 2620
Cdd:COG1196    256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2621 LQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLcVALKHEQTAKDNLQKELQIEASRCEA 2700
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL-LEALRAAAELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2701 LLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRgprespAHHALLRKLKEEKSRAAELQARLEQVQRQQEA 2780
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE------EEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2781 DVQKRRAELEREKEVRAaqarepgrclRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKeklR 2860
Cdd:COG1196    489 AAARLLLLLEAEADYEG----------FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE---D 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2861 ELELQRQRDEHKIRQLQR-TVQALEAKEEAAQRPEAERLQEERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNE 2939
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRaTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953366519 2940 KAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRR 3017
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 139-698 3.89e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.76  E-value: 3.89e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  139 ELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLrcsQET 218
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---AEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  219 AKLKEKLQSEMERNARAVESLKRdweserglclENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECAL 298
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEE----------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  299 RTLEAQHEEALRQLREDLQSERcqyvqdLELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS 378
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELL------EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  379 ARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERR 458
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  459 EQRVGPSLQPELAEnhrcHLTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTE---VV 535
Cdd:COG1196    522 LAGAVAVLIGVEAA----YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALargAI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  536 ARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERV------------------KHSLVEDHRE 597
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVtlegeggsaggsltggsrRELLAALLEA 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  598 ELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQILD 677
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570       580
                   ....*....|....*....|.
gi 1953366519  678 LEGSLVEQQGRLRQLEHGLEA 698
Cdd:COG1196    758 EPPDLEELERELERLEREIEA 778
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1369-1727 4.67e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 4.67e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1369 EARKQSEKDRAALlSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHL--------RSQRQFMDEQAVEREHE 1440
Cdd:TIGR02168  176 ETERKLERTRENL-DRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALlvlrleelREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1441 REEFQREIQRLEEQLRQAarprphgpRVSDVElLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREA 1520
Cdd:TIGR02168  255 LEELTAELQELEEKLEEL--------RLEVSE-LEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1521 AQLREELERQRDAMKALQQDKEALQEKQMSnlllvstLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRALQQRESEVLDL 1600
Cdd:TIGR02168  326 EELESKLDELAEELAELEEKLEELKEELES-------LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1601 KEQLGkmkddlvsksdevlhlnlELDAQSSRAAVSVRELQEENASLKAFLQNKEKeimcvsEQLEAQLAGMGSgALREVT 1680
Cdd:TIGR02168  399 NNEIE------------------RLEARLERLEDRRERLQQEIEELLKKLEEAEL------KELQAELEELEE-ELEELQ 453

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1953366519 1681 YDRSSEIEELRSIIENLRENQQRLQKEKAEEME--QLHEVIERLQEELS 1727
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQlqARLDSLERLQENLE 502
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 566-1066 1.80e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.80e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  566 ENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAE--EELTLMLHDLK 643
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEErlEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  644 EQAEAEKQSVINKfELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcgqepAGRVAPADQDWE 723
Cdd:COG1196    330 EELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA-----------EELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  724 LATRRLREDCALQ-LMQAQSRFLKERKELTEKFTAEQDAL--LQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEV 800
Cdd:COG1196    398 LAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEeeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  801 EELKASVESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEKEAS 880
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  881 HPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQ 960
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  961 LHCQEEPEVLECPSEPFLEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQIL 1040
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          490       500
                   ....*....|....*....|....*.
gi 1953366519 1041 SLSHEVEERRRDLEQLQQRRERENQE 1066
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1186-1511 1.67e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 1.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1186 SSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLM 1265
Cdd:TIGR02168  671 SILERRREIEE----LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1266 LELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAGT 1345
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1346 pAPIAHEDSALRREVECLtQEQSEARKQSEKDRAALLSQMKVFEAELEEQLsrheacakqaEELSALRQQMAALDKHLRS 1425
Cdd:TIGR02168  827 -ESLERRIAATERRLEDL-EEQIEELSEDIESLAAEIEELEELIEELESEL----------EALLNERASLEEALALLRS 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1426 QRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARpRPHGPRVsDVELLQEKLREK-SDGFNELVIKKELADRQVMIQEE 1504
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLEL-RLEGLEV-RIDNLQERLSEEySLTLEEAEALENKIEDDEEEARR 972


                   ....*..
gi 1953366519 1505 EIRRLEE 1511
Cdd:TIGR02168  973 RLKRLEN 979
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1637-1870 1.18e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1637 RELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGsgALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLH 1716
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIA--ALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1717 EVIERLQEELSLGAPAVPAAVDcelpavpapavGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAEL 1796
Cdd:COG4942    108 ELLRALYRLGRQPPLALLLSPE-----------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366519 1797 ERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAA 1870
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3069-3147 7.13e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 103.06  E-value: 7.13e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366519 3069 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAdkkTTTSRPFTRFRTAVRVVIAILRLRFLVKKW 3147
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD---RPSRKPRRKLKSAALAVIAIARMKRLAREW 77
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2461-3017 5.25e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 5.25e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2461 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAQlRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVELLAYKV 2540
Cdd:COG1196    188 LERLEDILGELERQLEPL----------ERQAEKAE-RYRELKEELKELEAELLLLKLRELEAELE-ELEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2541 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAA 2620
Cdd:COG1196    256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2621 LQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLcVALKHEQTAKDNLQKELQIEASRCEA 2700
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL-LEALRAAAELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2701 LLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRgprespAHHALLRKLKEEKSRAAELQARLEQVQRQQEA 2780
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE------EEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2781 DVQKRRAELEREKEVRAaqarepgrclRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKeklR 2860
Cdd:COG1196    489 AAARLLLLLEAEADYEG----------FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE---D 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2861 ELELQRQRDEHKIRQLQR-TVQALEAKEEAAQRPEAERLQEERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNE 2939
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRaTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953366519 2940 KAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRR 3017
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 139-698 3.89e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.76  E-value: 3.89e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  139 ELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLrcsQET 218
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---AEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  219 AKLKEKLQSEMERNARAVESLKRdweserglclENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECAL 298
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEE----------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  299 RTLEAQHEEALRQLREDLQSERcqyvqdLELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS 378
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELL------EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  379 ARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERR 458
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  459 EQRVGPSLQPELAEnhrcHLTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTE---VV 535
Cdd:COG1196    522 LAGAVAVLIGVEAA----YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALargAI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  536 ARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERV------------------KHSLVEDHRE 597
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVtlegeggsaggsltggsrRELLAALLEA 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  598 ELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQILD 677
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570       580
                   ....*....|....*....|.
gi 1953366519  678 LEGSLVEQQGRLRQLEHGLEA 698
Cdd:COG1196    758 EPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1369-1727 4.67e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 4.67e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1369 EARKQSEKDRAALlSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHL--------RSQRQFMDEQAVEREHE 1440
Cdd:TIGR02168  176 ETERKLERTRENL-DRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALlvlrleelREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1441 REEFQREIQRLEEQLRQAarprphgpRVSDVElLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREA 1520
Cdd:TIGR02168  255 LEELTAELQELEEKLEEL--------RLEVSE-LEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1521 AQLREELERQRDAMKALQQDKEALQEKQMSnlllvstLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRALQQRESEVLDL 1600
Cdd:TIGR02168  326 EELESKLDELAEELAELEEKLEELKEELES-------LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1601 KEQLGkmkddlvsksdevlhlnlELDAQSSRAAVSVRELQEENASLKAFLQNKEKeimcvsEQLEAQLAGMGSgALREVT 1680
Cdd:TIGR02168  399 NNEIE------------------RLEARLERLEDRRERLQQEIEELLKKLEEAEL------KELQAELEELEE-ELEELQ 453

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1953366519 1681 YDRSSEIEELRSIIENLRENQQRLQKEKAEEME--QLHEVIERLQEELS 1727
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQlqARLDSLERLQENLE 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1365-1894 5.30e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.91  E-value: 5.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1365 QEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSA----LRQQMAALDK---HLRSQRQFMDEQAVER 1437
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyeLLAELARLEQdiaRLEERRRELEERLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1438 EHEREEFQREIQRLEEQLRQAARprphgprvsDVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCR 1517
Cdd:COG1196    322 EEELAELEEELEELEEELEELEE---------ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1518 REAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcpvppadscpegpeVQLEAVQRALQQRESEV 1597
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE--------------EALEEAAEEEAELEEEE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1598 LDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGmgsgalR 1677
Cdd:COG1196    459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG------V 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1678 EVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVPAA------------VDCELPAVP 1745
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAlargaigaavdlVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1746 APA-----------VGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMAS-- 1812
Cdd:COG1196    613 ARYyvlgdtllgrtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEee 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1813 -----QIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRL 1887
Cdd:COG1196    693 leleeALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772


                   ....*..
gi 1953366519 1888 SRQLQVL 1894
Cdd:COG1196    773 EREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 2470-2911 1.41e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.41  E-value: 1.41e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2470 EQEKSLEHLRASDRSSLLSEIQalRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAykveQEKRIASD 2549
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVK--KAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA----EEARKADE 1282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2550 VQKTltEEQEKASSVRKLLVVEQTVVRDLRSELR----ECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELE 2625
Cdd:PTZ00121  1283 LKKA--EEKKKADEAKKAEEKKKADEAKKKAEEAkkadEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE 1360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2626 SERGKERALQSRLEEAQ--LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLA 2703
Cdd:PTZ00121  1361 AAEEKAEAAEKKKEEAKkkADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2704 QERGQLSELQRslEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEAdvq 2783
Cdd:PTZ00121  1441 EEAKKADEAKK--KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA--- 1515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2784 KRRAELEREKEVRAAQAREPGRCLRReghaSQQQAGLEPLQAglaAQEGRKDARRADVGPGRADAEMRPTGAK--EKLRE 2861
Cdd:PTZ00121  1516 KKAEEAKKADEAKKAEEAKKADEAKK----AEEKKKADELKK---AEELKKAEEKKKAEEAKKAEEDKNMALRkaEEAKK 1588

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1953366519 2862 LELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERL---QEERLGLERVRQQ 2911
Cdd:PTZ00121  1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkaEEEKKKVEQLKKK 1641
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2461-2801 4.29e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 4.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2461 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAqlrmthlqnqEKLQQLCAALTSAEARgsrqehqlrrqveLLAYKV 2540
Cdd:TIGR02168  188 LDRLEDILNELERQLKSL----------ERQAEKA----------ERYKELKAELRELELA-------------LLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2541 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQdnerllaSLGEAQKEVLQLRSVLDSKESNLRAA 2620
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE-------EIEELQKELYALANEISRLEQQKQIL 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2621 LQELESergkeraLQSRLEEAQLQhLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEA 2700
Cdd:TIGR02168  308 RERLAN-------LERQLEELEAQ-LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2701 LLAQERGQLSELQRSLEAEKGRSLELAAAL-----RHERLLTEQLSRGPR-ESPAHHALLRKLKEEKSRAAELQARLEQV 2774
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLerledRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERL 459

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1953366519 2775 QRQ----QEADVQKRRAELEREKEVRAAQAR 2801
Cdd:TIGR02168  460 EEAleelREELEEAEQALDAAERELAQLQAR 490
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 566-1066 1.80e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.80e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  566 ENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAE--EELTLMLHDLK 643
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEErlEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  644 EQAEAEKQSVINKfELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcgqepAGRVAPADQDWE 723
Cdd:COG1196    330 EELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA-----------EELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  724 LATRRLREDCALQ-LMQAQSRFLKERKELTEKFTAEQDAL--LQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEV 800
Cdd:COG1196    398 LAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEeeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  801 EELKASVESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEKEAS 880
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  881 HPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQ 960
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  961 LHCQEEPEVLECPSEPFLEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQIL 1040
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          490       500
                   ....*....|....*....|....*.
gi 1953366519 1041 SLSHEVEERRRDLEQLQQRRERENQE 1066
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLE 743
PTZ00121 PTZ00121
MAEBL; Provisional
 172-876 3.62e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.24  E-value: 3.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  172 ELRAMLNGRHAQELALLRSRQQQElELAREQHAREQEEMR----LRCSQETAKLKEKLQSEMERNARAVESLKRDWESER 247
Cdd:PTZ00121  1150 DAKRVEIARKAEDARKAEEARKAE-DAKKAEAARKAEEVRkaeeLRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEA 1228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  248 GLCLENLRRELSAKHRSELENLQDQFkRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERCQYVQDL 327
Cdd:PTZ00121  1229 VKKAEEAKKDAEEAKKAEEERNNEEI-RKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  328 ----ELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDASARTPHGEELEQRErecgvqQQRRGR 403
Cdd:PTZ00121  1308 kkkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE------AKKKAD 1381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  404 RAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERREQRvgpslqpelAENHRchltawtS 483
Cdd:PTZ00121  1382 AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKK---------AEEAK-------K 1445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  484 SLEAQQQAGlvETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEvvarglglEAEHRLKLLLLQTELKEEMDvl 563
Cdd:PTZ00121  1446 ADEAKKKAE--EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE--------EAKKKADEAKKAAEAKKKAD-- 1513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  564 klENRNLHEKLQHEVCLKEDLERVKHSLVEdhREELKKANErlqlVKQELKDKEAEWKVASEDlKRKAEEELTLMLHDLK 643
Cdd:PTZ00121  1514 --EAKKAEEAKKADEAKKAEEAKKADEAKK--AEEKKKADE----LKKAEELKKAEEKKKAEE-AKKAEEDKNMALRKAE 1584

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  644 EQAEAEKQSVINKFELREiKMRQLQDQQAAQildlegslvEQQGRLRQLEHGLEAEECPRCGHCGQEPAGRVAPADQdwe 723
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYE-EEKKMKAEEAKK---------AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE--- 1651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  724 laTRRLREDCALQLMQAQSRFLKERKELTEKFTAEQD------ALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRR 797
Cdd:PTZ00121  1652 --LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDekkaaeALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK 1729

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366519  798 AEVEELKASVESERWALAEARVAELQTEHAAAISALEARHSallgslESRHLSEVQAMREEHRQALEQLRVDLEKQLQE 876
Cdd:PTZ00121  1730 IKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA------EEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1186-1511 1.67e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 1.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1186 SSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLM 1265
Cdd:TIGR02168  671 SILERRREIEE----LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1266 LELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAGT 1345
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1346 pAPIAHEDSALRREVECLtQEQSEARKQSEKDRAALLSQMKVFEAELEEQLsrheacakqaEELSALRQQMAALDKHLRS 1425
Cdd:TIGR02168  827 -ESLERRIAATERRLEDL-EEQIEELSEDIESLAAEIEELEELIEELESEL----------EALLNERASLEEALALLRS 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1426 QRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARpRPHGPRVsDVELLQEKLREK-SDGFNELVIKKELADRQVMIQEE 1504
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLEL-RLEGLEV-RIDNLQERLSEEySLTLEEAEALENKIEDDEEEARR 972


                   ....*..
gi 1953366519 1505 EIRRLEE 1511
Cdd:TIGR02168  973 RLKRLEN 979
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1364-1726 1.10e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.15  E-value: 1.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1364 TQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFM---DEQAVEREHE 1440
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKrklEEKIRELEER 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1441 REEFQREIQRLEEQLRQAARPRPHGPRVSDVELLQEKLREKSDGfnelvIKKELADRQVMIQ--EEEIRRLEETNascrR 1518
Cdd:PRK03918   268 IEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELRE-----IEKRLSRLEEEINgiEERIKELEEKE----E 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1519 EAAQLREELERQRDAMKALQQDKEALQEkqmsnlllVSTLQSKLDEGRCPVppADSCPEGPEVQLEAVQRALQQRESEVL 1598
Cdd:PRK03918   339 RLEELKKKLKELEKRLEELEERHELYEE--------AKAKKEELERLKKRL--TGLTPEKLEKELEELEKAKEEIEEEIS 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1599 DLKEQLGKMKDDLVSKSDEVlhlnLELDAQSSRAAVSVRELQEEN-----ASLKAFLQNKEKEIMCVSEQLEAQLAgmgs 1673
Cdd:PRK03918   409 KITARIGELKKEIKELKKAI----EELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKELKEIEEKERKLRK---- 480

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1953366519 1674 gALREV--TYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEEL 1726
Cdd:PRK03918   481 -ELRELekVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKL 534
PTZ00121 PTZ00121
MAEBL; Provisional
 1346-2072 1.66e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 1.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1346 PAPIAHEDSALRREVEclTQEQSEARKQSEKDRaallsqmKVFEAELEEQLSRHEAcAKQAEELSALRQQMAALD-KHLR 1424
Cdd:PTZ00121  1074 PSYKDFDFDAKEDNRA--DEATEEAFGKAEEAK-------KTETGKAEEARKAEEA-KKKAEDARKAEEARKAEDaRKAE 1143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1425 SQRQFMDEQAVEREHEREEFQR-EIQRLEEQLRQAARPRphgpRVSDVELLQEkLREKSDgfnelVIKKELADRQvmiqe 1503
Cdd:PTZ00121  1144 EARKAEDAKRVEIARKAEDARKaEEARKAEDAKKAEAAR----KAEEVRKAEE-LRKAED-----ARKAEAARKA----- 1208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1504 EEIRRLEETNascRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRCPVPPADSCPEGPEV-- 1581
Cdd:PTZ00121  1209 EEERKAEEAR---KAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELkk 1285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1582 -----QLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELD--AQSSRAAVSVRELQEENASLKAFLQNKE 1654
Cdd:PTZ00121  1286 aeekkKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKkkAEEAKKAAEAAKAEAEAAADEAEAAEEK 1365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1655 KEimcvSEQLEAQLAGMGSGALREVTyDRSSEIEELRSIIENLRENQQRLQKEKAEE--MEQLHEVIERLQEELSLGAPA 1732
Cdd:PTZ00121  1366 AE----AAEKKKEEAKKKADAAKKKA-EEKKKADEAKKKAEEDKKKADELKKAAAAKkkADEAKKKAEEKKKADEAKKKA 1440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1733 VPAAVDCELPAVPAPAVGPEALAAAGAASRLFAE-----QEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEV 1807
Cdd:PTZ00121  1441 EEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEakkkaEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE 1520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1808 QAMASQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELetilaafsrfRRTLERQPLAAEDEPPELQRLRVQcvrl 1887
Cdd:PTZ00121  1521 AKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEE----------KKKAEEAKKAEEDKNMALRKAEEA---- 1586

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1888 srqlqvlnqrflrcqkeadkQQARGARLRPRGARGLQGPGPRAEEASRDEASQQDVDSRQVASATQGQVRDPQNAVNDDL 1967
Cdd:PTZ00121  1587 --------------------KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK 1646

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1968 QPAElpvtsgppGLLKQDSVMSVLAVCQRQLESELLLLKNEMHLRTEDRGKAPARMKNKENllEDRQLQKVGliSQVKEL 2047
Cdd:PTZ00121  1647 KKAE--------ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE--EAKKAEELK--KKEAEE 1714

                          730       740
                   ....*....|....*....|....*
gi 1953366519 2048 QEKLNHLVRSVNFQNIETEDFKSQQ 2072
Cdd:PTZ00121  1715 KKKAEELKKAEEENKIKAEEAKKEA 1739
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1142-1712 1.72e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 53.96  E-value: 1.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1142 LEETWPGSEAALLELDRSLPECVEMPSEAEISSHIC----ESFFMSPESSLEYE---QPIRRIYQSLGLAVEGLLeLALD 1214
Cdd:pfam05483  122 IQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCnllkETCARSAEKTKKYEyerEETRQVYMDLNNNIEKMI-LAFE 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1215 STR-QLEEAR-----QIHSRFEKEFSCKNEETAQVVRKQQQ----LLERLEEENAARTrLMLELHQAQGIIEGFKEEKAS 1284
Cdd:pfam05483  201 ELRvQAENARlemhfKLKEDHEKIQHLEEEYKKEINDKEKQvsllLIQITEKENKMKD-LTFLLEESRDKANQLEEKTKL 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1285 LQEALCRQETAEHGLAEELEGLRQQLQQAAQQQA--------------ELKEENSALWSQKEASAAEAEAREAGTPAPIA 1350
Cdd:pfam05483  280 QDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKaleedlqiatkticQLTEEKEAQMEELNKAKAAHSFVVTEFEATTC 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1351 HEDSALRREVECLTQEQSE--------ARKQSE--------KDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQ 1414
Cdd:pfam05483  360 SLEELLRTEQQRLEKNEDQlkiitmelQKKSSEleemtkfkNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQ 439

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1415 QMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDVELLQEK--LREKSDGFNELviKK 1492
Cdd:pfam05483  440 ELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKelTQEASDMTLEL--KK 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1493 ELADRQVMIQEEE-----IRRLEETNASCRREAAQLREELERQRDAMKAlQQDKEALQEKQMSNLLLVSTLQSKLDEGRC 1567
Cdd:pfam05483  518 HQEDIINCKKQEErmlkqIENLEEKEMNLRDELESVREEFIQKGDEVKC-KLDKSEENARSIEYEVLKKEKQMKILENKC 596

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1568 pvppadscpEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSV----RELQEEN 1643
Cdd:pfam05483  597 ---------NNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIdnyqKEIEDKK 667

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366519 1644 ASLKAFLQNKEKEIMCVSEQLEAQlagmgsgalREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEM 1712
Cdd:pfam05483  668 ISEEKLLEEVEKAKAIADEAVKLQ---------KEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSEL 727
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 137-875 3.62e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.84  E-value: 3.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  137 SLELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQeLALLRSRQQQELELAREQHAREQEEMRLRCSQ 216
Cdd:pfam12128  252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQ-WKEKRDELNGELSAADAAVAKDRSELEALEDQ 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  217 ETAKLKEKLQSEMERNARAvESLKRDWE--SERGLCLENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQA 294
Cdd:pfam12128  331 HGAFLDADIETAAADQEQL-PSWQSELEnlEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQ 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  295 ECALRTLEAQHEEALRQLREDLQSErcqyVQDLELRLRDQEVEKQLELESLRASYAEL--KAQSQEEIRRLWSQLESPRP 372
Cdd:pfam12128  410 LAVAEDDLQALESELREQLEAGKLE----FNEEEYRLKSRLGELKLRLNQATATPELLlqLENFDERIERAREEQEAANA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  373 DRQDAsartphgeeleQRERecgvqQQRRGRRAEQESELGQSPEGAAERgredpvllEQRLQDATEEPSLESGGIGPSSM 452
Cdd:pfam12128  486 EVERL-----------QSEL-----RQARKRRDQASEALRQASRRLEER--------QSALDELELQLFPQAGTLLHFLR 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  453 REGERREQRVGPSLQPELAenHRCHLTAwtssleaqqqaglVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDT 532
Cdd:pfam12128  542 KEAPDWEQSIGKVISPELL--HRTDLDP-------------EVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  533 EVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLEnrnlheklqhevclkedLERVKHSLvEDHREELKKANERLQLVKQE 612
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASRE-----------------ETFARTAL-KNARLDLRRLFDEKQSEKDK 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  613 LKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQsvinkfELREIKMRQLQDQQAaqildLEGSLVEQQGRLRQL 692
Cdd:pfam12128  669 KNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKE------QKREARTEKQAYWQV-----VEGALDAQLALLKAA 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  693 EHGLEAEECPRCGHCGQEPAGRVAPADQDWELATRRLREdcALQLMQAQSRFLKERKELTEKFTAEQDALLQEAQEKHAc 772
Cdd:pfam12128  738 IAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKRE--IRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLAT- 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  773 dmrlLQERHQQHVLSLTAQLeARRRAEVEELKASVESERWAL--AEARVAELQTEHAAAISALEARHSALLGSLESRHLS 850
Cdd:pfam12128  815 ----QLSNIERAISELQQQL-ARLIADTKLRRAKLEMERKASekQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIG 889

                          730       740
                   ....*....|....*....|....*
gi 1953366519  851 EVQAMREEHRQALEQLRVDLEKQLQ 875
Cdd:pfam12128  890 ERLAQLEDLKLKRDYLSESVKKYVE 914
PTZ00121 PTZ00121
MAEBL; Provisional
 1214-1512 5.54e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.37  E-value: 5.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1214 DSTRQLEEARQIHSRFEKEFSCKNEET--AQVVRKQQQLlERLEEENAARTRLMLELHQAQgiiEGFKEEKASLQEALCR 1291
Cdd:PTZ00121  1525 DEAKKAEEAKKADEAKKAEEKKKADELkkAEELKKAEEK-KKAEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKL 1600

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1292 QETAEHGLAEELEglrqQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQ---- 1367
Cdd:PTZ00121  1601 YEEEKKMKAEEAK----KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkk 1676

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1368 -SEARKQSEKDRAAllsqmkvfeaelEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQfmdeqavEREHEREEFQR 1446
Cdd:PTZ00121  1677 aEEAKKAEEDEKKA------------AEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEE-------ENKIKAEEAKK 1737

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1953366519 1447 EIQRLEEQLRQAARPRPHGPRVSDVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEET 1512
Cdd:PTZ00121  1738 EAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDI 1803
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 581-879 1.71e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.74  E-value: 1.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  581 KEDLERVkhslvEDHREELKKANERLQL----------VKQELKDKE-----AEWKVASEDLKR--KAEEELTLMLHDLK 643
Cdd:TIGR02168  185 RENLDRL-----EDILNELERQLKSLERqaekaerykeLKAELRELElallvLRLEELREELEElqEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  644 EQ-AEAEKQSVINKFELREIKMRQLQDQQ-----AAQILDLEGSLVEQQGRLRQLEHGLEAEECPRCGHcgQEPAGRVAP 717
Cdd:TIGR02168  260 AElQELEEKLEELRLEVSELEEEIEELQKelyalANEISRLEQQKQILRERLANLERQLEELEAQLEEL--ESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  718 ADQDWELATRRLREDCALQLmQAQSRFLKERKELTEKFTAEQDALLQEAQEKHacDMRLLQERHQQHVLSLTAQLEaRRR 797
Cdd:TIGR02168  338 ELAELEEKLEELKEELESLE-AELEELEAELEELESRLEELEEQLETLRSKVA--QLELQIASLNNEIERLEARLE-RLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  798 AEVEELKASVESERWALAEARVAELQT---EHAAAISALEARHSALlgsleSRHLSEVQAMREEHRQALEQLRVDLEKQL 874
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAeleELEEELEELQEELERL-----EEALEELREELEEAEQALDAAERELAQLQ 488


                   ....*
gi 1953366519  875 QEKEA 879
Cdd:TIGR02168  489 ARLDS 493
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2473-2902 1.79e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.53  E-value: 1.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2473 KSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRR-----------QVELLAYKVE 2541
Cdd:pfam12128  268 KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEAledqhgafldaDIETAAADQE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2542 QEKRIASDVQ------KTLTEEQ---EKASSVRKLLVVEQ--TVVRDLRSELRECKQDNERLLASL-GEAQKEVLQLRSV 2609
Cdd:pfam12128  348 QLPSWQSELEnleerlKALTGKHqdvTAKYNRRRSKIKEQnnRDIAGIKDKLAKIREARDRQLAVAeDDLQALESELREQ 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2610 LDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREgQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQK 2689
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLE-NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASE 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2690 ELQieasRCEALLAQERGQLSELQRSLEAEKGRSLELaaaLRHERLLTEQlSRGPRESPA--HHALLRKLKEEKSRAAEL 2767
Cdd:pfam12128  507 ALR----QASRRLEERQSALDELELQLFPQAGTLLHF---LRKEAPDWEQ-SIGKVISPEllHRTDLDPEVWDGSVGGEL 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2768 -----QARLEQVQRQQEADvqkrraeLEREKEVRAAQAREPgrclRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVG 2842
Cdd:pfam12128  579 nlygvKLDLKRIDVPEWAA-------SEEELRERLDKAEEA----LQSAREKQAAAEEQLVQANGELEKASREETFARTA 647

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2843 PGRADAEMRPTGAKEKLRELELQRQRDEHKiRQLQRTVQALEAKEEAAQRPEAERLQEER 2902
Cdd:pfam12128  648 LKNARLDLRRLFDEKQSEKDKKNKALAERK-DSANERLNSLEAQLKQLDKKHQAWLEEQK 706
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 169-439 2.56e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 2.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  169 ALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAvESLKRDWESERG 248
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI-EQLEQEEEKLKE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  249 LcLENLRRELSAKHRsELENLqdqfKRELSEQKAELEKIFQAKNQAECALRTLEAQ-HEEALRQLREDLQSERcQYVQDL 327
Cdd:TIGR02169  738 R-LEELEEDLSSLEQ-EIENV----KSELKELEARIEELEEDLHKLEEALNDLEARlSHSRIPEIQAELSKLE-EEVSRI 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  328 ELRLrdQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS----------ARTPHGEELEQRERECGVQ 397
Cdd:TIGR02169  811 EARL--REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLngkkeeleeeLEELEAALRDLESRLGDLK 888

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1953366519  398 QQRRGRRA---EQESELGQSpEGAAERGREDPVLLEQRLQDATEE 439
Cdd:TIGR02169  889 KERDELEAqlrELERKIEEL-EAQIEKKRKRLSELKAKLEALEEE 932
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1637-1870 1.18e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1637 RELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGsgALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLH 1716
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIA--ALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1717 EVIERLQEELSLGAPAVPAAVDcelpavpapavGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAEL 1796
Cdd:COG4942    108 ELLRALYRLGRQPPLALLLSPE-----------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366519 1797 ERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAA 1870
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1252-1466 2.36e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1252 ERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQK 1331
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1332 EASAAEAEAR--------EAGTPAPIAHEDSALR-----REVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSR 1398
Cdd:COG4942    100 EAQKEELAELlralyrlgRQPPLALLLSPEDFLDavrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953366519 1399 HEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGP 1466
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3069-3147 7.13e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 103.06  E-value: 7.13e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366519 3069 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAdkkTTTSRPFTRFRTAVRVVIAILRLRFLVKKW 3147
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD---RPSRKPRRKLKSAALAVIAIARMKRLAREW 77
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2461-3017 5.25e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 5.25e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2461 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAQlRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVELLAYKV 2540
Cdd:COG1196    188 LERLEDILGELERQLEPL----------ERQAEKAE-RYRELKEELKELEAELLLLKLRELEAELE-ELEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2541 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAA 2620
Cdd:COG1196    256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2621 LQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLcVALKHEQTAKDNLQKELQIEASRCEA 2700
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL-LEALRAAAELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2701 LLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRgprespAHHALLRKLKEEKSRAAELQARLEQVQRQQEA 2780
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE------EEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2781 DVQKRRAELEREKEVRAaqarepgrclRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKeklR 2860
Cdd:COG1196    489 AAARLLLLLEAEADYEG----------FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE---D 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2861 ELELQRQRDEHKIRQLQR-TVQALEAKEEAAQRPEAERLQEERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNE 2939
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRaTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953366519 2940 KAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRR 3017
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2456-2913 1.53e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.38  E-value: 1.53e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2456 EHSSLLERLEKVVQEQEKSLEHLRAS--DRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQV 2533
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLEleELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2534 ELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSvLDSK 2613
Cdd:COG1196    330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-LEEA 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2614 ESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQI 2693
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2694 EASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQ 2773
Cdd:COG1196    489 AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2774 -----VQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQQQAGLEPLQAGLAA--------QEGRKDARRAD 2840
Cdd:COG1196    569 akagrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAarleaalrRAVTLAGRLRE 648

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1953366519 2841 VGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERLGLERVRQQLL 2913
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 139-698 3.89e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.76  E-value: 3.89e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  139 ELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLrcsQET 218
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---AEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  219 AKLKEKLQSEMERNARAVESLKRdweserglclENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECAL 298
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEE----------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  299 RTLEAQHEEALRQLREDLQSERcqyvqdLELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS 378
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELL------EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  379 ARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERR 458
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  459 EQRVGPSLQPELAEnhrcHLTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTE---VV 535
Cdd:COG1196    522 LAGAVAVLIGVEAA----YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALargAI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  536 ARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERV------------------KHSLVEDHRE 597
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVtlegeggsaggsltggsrRELLAALLEA 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  598 ELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQILD 677
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570       580
                   ....*....|....*....|.
gi 1953366519  678 LEGSLVEQQGRLRQLEHGLEA 698
Cdd:COG1196    758 EPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1369-1727 4.67e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 4.67e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1369 EARKQSEKDRAALlSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHL--------RSQRQFMDEQAVEREHE 1440
Cdd:TIGR02168  176 ETERKLERTRENL-DRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALlvlrleelREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1441 REEFQREIQRLEEQLRQAarprphgpRVSDVElLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREA 1520
Cdd:TIGR02168  255 LEELTAELQELEEKLEEL--------RLEVSE-LEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1521 AQLREELERQRDAMKALQQDKEALQEKQMSnlllvstLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRALQQRESEVLDL 1600
Cdd:TIGR02168  326 EELESKLDELAEELAELEEKLEELKEELES-------LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1601 KEQLGkmkddlvsksdevlhlnlELDAQSSRAAVSVRELQEENASLKAFLQNKEKeimcvsEQLEAQLAGMGSgALREVT 1680
Cdd:TIGR02168  399 NNEIE------------------RLEARLERLEDRRERLQQEIEELLKKLEEAEL------KELQAELEELEE-ELEELQ 453

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1953366519 1681 YDRSSEIEELRSIIENLRENQQRLQKEKAEEME--QLHEVIERLQEELS 1727
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQlqARLDSLERLQENLE 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1365-1894 5.30e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.91  E-value: 5.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1365 QEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSA----LRQQMAALDK---HLRSQRQFMDEQAVER 1437
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyeLLAELARLEQdiaRLEERRRELEERLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1438 EHEREEFQREIQRLEEQLRQAARprphgprvsDVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCR 1517
Cdd:COG1196    322 EEELAELEEELEELEEELEELEE---------ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1518 REAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcpvppadscpegpeVQLEAVQRALQQRESEV 1597
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE--------------EALEEAAEEEAELEEEE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1598 LDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGmgsgalR 1677
Cdd:COG1196    459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG------V 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1678 EVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVPAA------------VDCELPAVP 1745
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAlargaigaavdlVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1746 APA-----------VGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMAS-- 1812
Cdd:COG1196    613 ARYyvlgdtllgrtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEee 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1813 -----QIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRL 1887
Cdd:COG1196    693 leleeALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772


                   ....*..
gi 1953366519 1888 SRQLQVL 1894
Cdd:COG1196    773 EREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1199-1738 8.14e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 8.14e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1199 QSLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGF 1278
Cdd:COG1196    228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1279 KEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAreagtpapIAHEDSALRR 1358
Cdd:COG1196    308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE--------AEAELAEAEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1359 EVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVERE 1438
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1439 HEREEFQREIQRLEEQLRQAARPRPHGPRVSDVELLQEKLREKSDGFNELVIKKELADRQ--------VMIQEEEIRRLE 1510
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavaVLIGVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1511 ETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcPVPPADSCPEGPEVQLEAVQRAL 1590
Cdd:COG1196    540 LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARG-AIGAAVDLVASDLREADARYYVL 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1591 QQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEimcvsEQLEAQLAG 1670
Cdd:COG1196    619 GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL-----AERLAEEEL 693

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953366519 1671 MGSGALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVPAAVD 1738
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761
PTZ00121 PTZ00121
MAEBL; Provisional
 2470-2911 1.41e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.41  E-value: 1.41e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2470 EQEKSLEHLRASDRSSLLSEIQalRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAykveQEKRIASD 2549
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVK--KAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA----EEARKADE 1282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2550 VQKTltEEQEKASSVRKLLVVEQTVVRDLRSELR----ECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELE 2625
Cdd:PTZ00121  1283 LKKA--EEKKKADEAKKAEEKKKADEAKKKAEEAkkadEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE 1360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2626 SERGKERALQSRLEEAQ--LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLA 2703
Cdd:PTZ00121  1361 AAEEKAEAAEKKKEEAKkkADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2704 QERGQLSELQRslEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEAdvq 2783
Cdd:PTZ00121  1441 EEAKKADEAKK--KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA--- 1515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2784 KRRAELEREKEVRAAQAREPGRCLRReghaSQQQAGLEPLQAglaAQEGRKDARRADVGPGRADAEMRPTGAK--EKLRE 2861
Cdd:PTZ00121  1516 KKAEEAKKADEAKKAEEAKKADEAKK----AEEKKKADELKK---AEELKKAEEKKKAEEAKKAEEDKNMALRkaEEAKK 1588

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1953366519 2862 LELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERL---QEERLGLERVRQQ 2911
Cdd:PTZ00121  1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkaEEEKKKVEQLKKK 1641
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2461-2801 4.29e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 4.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2461 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAqlrmthlqnqEKLQQLCAALTSAEARgsrqehqlrrqveLLAYKV 2540
Cdd:TIGR02168  188 LDRLEDILNELERQLKSL----------ERQAEKA----------ERYKELKAELRELELA-------------LLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2541 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQdnerllaSLGEAQKEVLQLRSVLDSKESNLRAA 2620
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE-------EIEELQKELYALANEISRLEQQKQIL 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2621 LQELESergkeraLQSRLEEAQLQhLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEA 2700
Cdd:TIGR02168  308 RERLAN-------LERQLEELEAQ-LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2701 LLAQERGQLSELQRSLEAEKGRSLELAAAL-----RHERLLTEQLSRGPR-ESPAHHALLRKLKEEKSRAAELQARLEQV 2774
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLerledRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERL 459

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1953366519 2775 QRQ----QEADVQKRRAELEREKEVRAAQAR 2801
Cdd:TIGR02168  460 EEAleelREELEEAEQALDAAERELAQLQAR 490
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1255-1918 3.35e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.70  E-value: 3.35e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1255 EEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWS----- 1329
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANeisrl 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1330 -QKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQSEARKQSE---KDRAALLSQMKVFEAELEEQLSRHEACAKQ 1405
Cdd:TIGR02168  301 eQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEelkEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1406 AEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAarprphgprvsDVELLQEKLREKSDGF 1485
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA-----------ELKELQAELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1486 NELVIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREELerqrDAMKALQQDKEALQEkQMSNLLLVstlQSKLDEG 1565
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL----DSLERLQENLEGFSE-GVKALLKN---QSGLSGI 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1566 RCPVPPADSCPEGPEVQLEAVqralqqresevldlkeqLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVREL-----Q 1640
Cdd:TIGR02168  522 LGVLSELISVDEGYEAAIEAA-----------------LGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLdsikgT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1641 EENASLKAFLQNKE------KEIMCVSEQLEAQLAGMGSGAL-------------------REVTYD------------- 1682
Cdd:TIGR02168  585 EIQGNDREILKNIEgflgvaKDLVKFDPKLRKALSYLLGGVLvvddldnalelakklrpgyRIVTLDgdlvrpggvitgg 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1683 ---RSSEIEELRSIIENLRENQQRLQkekaEEMEQLHEVIERLQEELSLGAPAVPAAVDCELPAVPAPAVGPEALAAAGA 1759
Cdd:TIGR02168  665 sakTNSSILERRREIEELEEKIEELE----EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1760 ASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALR---EAEVQAMASQIQAFEAALRAKEARLAERDLEID 1836
Cdd:TIGR02168  741 EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIeelEAQIEQLKEELKALREALDELRAELTLLNEEAA 820

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1837 AMKRQKLAHSAELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRLSRQLQVLnqrflrcQKEADKQQARGARLR 1916
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL-------LNERASLEEALALLR 893


                   ..
gi 1953366519 1917 PR 1918
Cdd:TIGR02168  894 SE 895
PTZ00121 PTZ00121
MAEBL; Provisional
 2519-2902 1.79e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 1.79e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2519 EARGSRQEHQLRRQVELLAYKVEqEKRIASDVQKTLTEEQEKASSVRKllvveQTVVRDLRSELRECKQDNERLLASLGE 2598
Cdd:PTZ00121  1458 KAEEAKKKAEEAKKADEAKKKAE-EAKKADEAKKKAEEAKKKADEAKK-----AAEAKKKADEAKKAEEAKKADEAKKAE 1531

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2599 AQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQlcvALK 2678
Cdd:PTZ00121  1532 EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK---KMK 1608

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2679 HEQTAKDNLQKELQIEASRCEallaQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLK 2758
Cdd:PTZ00121  1609 AEEAKKAEEAKIKAEELKKAE----EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2759 EEKSRAAELQAR-------LEQVQRQQEADVQKRRaELEREKEVRAAQAREpgrcLRREGHASQQQagleplqaglaAQE 2831
Cdd:PTZ00121  1685 EDEKKAAEALKKeaeeakkAEELKKKEAEEKKKAE-ELKKAEEENKIKAEE----AKKEAEEDKKK-----------AEE 1748

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953366519 2832 GRKDarradvgpgradaemrpTGAKEKLRELELQRQRDEHKIRQLQRTVqaleAKEEAAQRPEAERLQEER 2902
Cdd:PTZ00121  1749 AKKD-----------------EEEKKKIAHLKKEEEKKAEEIRKEKEAV----IEEELDEEDEKRRMEVDK 1798
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 566-1066 1.80e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.80e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  566 ENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAE--EELTLMLHDLK 643
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEErlEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  644 EQAEAEKQSVINKfELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcgqepAGRVAPADQDWE 723
Cdd:COG1196    330 EELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA-----------EELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  724 LATRRLREDCALQ-LMQAQSRFLKERKELTEKFTAEQDAL--LQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEV 800
Cdd:COG1196    398 LAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEeeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  801 EELKASVESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEKEAS 880
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  881 HPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQ 960
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  961 LHCQEEPEVLECPSEPFLEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQIL 1040
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          490       500
                   ....*....|....*....|....*.
gi 1953366519 1041 SLSHEVEERRRDLEQLQQRRERENQE 1066
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2459-3022 2.04e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 2.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2459 SLLERLEKVvQEQEKSLEHLRASdRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAY 2538
Cdd:TIGR02168  236 ELREELEEL-QEELKEAEEELEE-LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2539 KVEQEKRIASD---VQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKE- 2614
Cdd:TIGR02168  314 LERQLEELEAQleeLESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEl 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2615 ---------SNLRAALQELESERGKER----ALQSRLEEAQLQHLQRE-GQSSKTLEELRASLEKQFAQSSQLCVALKHE 2680
Cdd:TIGR02168  394 qiaslnneiERLEARLERLEDRRERLQqeieELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2681 QTAKDNLQKELQIEASRCEALLAQER--------------------GQLSELQRSLEAEKGRSLELAAALRhERLL---- 2736
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQEnlegfsegvkallknqsglsGILGVLSELISVDEGYEAAIEAALG-GRLQavvv 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2737 -TEQLSRGPRESPAHHALLRK--LKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHA 2813
Cdd:TIGR02168  553 eNLNAAKKAIAFLKQNELGRVtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLD 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2814 S-QQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQr 2892
Cdd:TIGR02168  633 NaLELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELE- 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2893 peaERLQEERLGLERVRQQLLCAAGLLTSFisRTVDRTISDWTSSNEKAVTSLLHTLEELKSELSTPSSSQKKMTAELQT 2972
Cdd:TIGR02168  712 ---EELEQLRKELEELSRQISALRKDLARL--EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1953366519 2973 --QLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRRGVCSK 3022
Cdd:TIGR02168  787 leAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1245-1819 3.14e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 3.14e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1245 RKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEEN 1324
Cdd:COG1196    239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1325 SALwsqkeasaaeaeareagtpapiAHEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAK 1404
Cdd:COG1196    319 EEL----------------------EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1405 QAEELSALRQQMAALDKH---LRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRphgprvsdvELLQEKLREK 1481
Cdd:COG1196    377 AEEELEELAEELLEALRAaaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE---------EEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1482 SDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQ-DKEALQEKQMSNLLLVSTLQS 1560
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGfLEGVKAALLLAGLRGLAGAVA 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1561 KLDEGRCPVPPADSCPEGPEVQLEAVQRALQQRESEVLDLKEQLGKM----------------KDDLVSKSDEVLHLNLE 1624
Cdd:COG1196    528 VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAtflpldkiraraalaaALARGAIGAAVDLVASD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1625 LDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSGALREVTYDRSSEIEELRSIIENLRENQQRL 1704
Cdd:COG1196    608 LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1705 QKEKAEEMEQLHEVIERLQEELSLGApavpaavdcelpavpapavgpEALAAAGAASRLFAEQEHRHGQALEALQQRLQA 1784
Cdd:COG1196    688 LAEEELELEEALLAEEEEERELAEAE---------------------EERLEEELEEEALEEQLEAEREELLEELLEEEE 746

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1953366519 1785 AEEAAAGQLAELERSAALREAEVQAMASQIQAFEA 1819
Cdd:COG1196    747 LLEEEALEELPEPPDLEELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2420-2885 5.21e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 5.21e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2420 LDWRGEFLQAVQEAFGKEREMLRAELQprpcgsapgEHSSLLERLEKVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRm 2499
Cdd:COG1196    321 LEEELAELEEELEELEEELEELEEELE---------EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE- 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2500 tHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLR 2579
Cdd:COG1196    391 -ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2580 SELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAAL------------QELESERGKERALQSRLEEAQLQHLQ 2647
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKaalllaglrglaGAVAVLIGVEAAYEAALEAALAAALQ 549

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2648 REG-QSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLEL 2726
Cdd:COG1196    550 NIVvEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2727 AAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRC 2806
Cdd:COG1196    630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366519 2807 LRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELelqrqrdEHKIRQLQRTVQALEA 2885
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL-------ERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2579-2900 5.65e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 5.65e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2579 RSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQ---SRLEEAQLQHLQREGQSSKT 2655
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkdlARLEAEVEQLEERIAQLSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2656 LEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQieasRCEALLAQERGQLSELQRSLEAEKGRSLElaaalrherl 2735
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE----QLKEELKALREALDELRAELTLLNEEAAN---------- 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2736 LTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQ 2815
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2816 QQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRE---------------LELQRQRDEHKIRQLQRTV 2880
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEeysltleeaealenkIEDDEEEARRRLKRLENKI 981

                          330       340
                   ....*....|....*....|....*
gi 1953366519 2881 QA-----LEAKEEAAQrpEAERLQE 2900
Cdd:TIGR02168  982 KElgpvnLAAIEEYEE--LKERYDF 1004
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2459-2802 1.05e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 1.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2459 SLLERLEKVvQEQEKSLEHLRAS---DRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVEL 2535
Cdd:TIGR02169  671 SEPAELQRL-RERLEGLKRELSSlqsELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE-ELEEDLSS 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2536 LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLvvEQTVVRDLRSELREckqdnerLLASLGEAQKEVLQLRSVLDSKES 2615
Cdd:TIGR02169  749 LEQEIENVKSELKELEARIEELEEDLHKLEEAL--NDLEARLSHSRIPE-------IQAELSKLEEEVSRIEARLREIEQ 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2616 NLRAALQELESERGKERALQSRLEEAQLQHLQREGQ---SSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQK--- 2689
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEienLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAqlr 899

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2690 ELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELaaalrherlltEQLSRGPRESPAHHALLRKLKEEKSRAAELQA 2769
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI-----------EDPKGEDEEIPEEELSLEDVQAELQRVEEEIR 968

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 1953366519 2770 RLEQVQR---QQEADVQKRRAELEREKEVRAAQARE 2802
Cdd:TIGR02169  969 ALEPVNMlaiQEYEEVLKRLDELKEKRAKLEEERKA 1004
PTZ00121 PTZ00121
MAEBL; Provisional
 2462-2910 1.45e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.39  E-value: 1.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2462 ERLEKVVQEQEKSLEHLRA-SDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAE---ARGSRQEHQLRRQVELLA 2537
Cdd:PTZ00121  1318 DEAKKKAEEAKKKADAAKKkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAkkkADAAKKKAEEKKKADEAK 1397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2538 YKVEQEKRIASDVQKTlTEEQEKASSVRKLlVVEQTVVRDLRSELRECKQDNErlLASLGEAQKEVLQLRSvlDSKESNL 2617
Cdd:PTZ00121  1398 KKAEEDKKKADELKKA-AAAKKKADEAKKK-AEEKKKADEAKKKAEEAKKADE--AKKKAEEAKKAEEAKK--KAEEAKK 1471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2618 RAALQELESERGKERALQSRLEEAQ--LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEA 2695
Cdd:PTZ00121  1472 ADEAKKKAEEAKKADEAKKKAEEAKkkADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADEL 1551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2696 SRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRH-ERLLTEQLSRGPRESpahhallRKLKEEKSRAA-ELQARLEQ 2773
Cdd:PTZ00121  1552 KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKaEEARIEEVMKLYEEE-------KKMKAEEAKKAeEAKIKAEE 1624

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2774 VQRQQEADVQKRRAELEREKEVRAAQ---AREPGRCLRREGHASQQQAGLEPLQAGLAAQEGRKDARRA---DVGPGRAD 2847
Cdd:PTZ00121  1625 LKKAEEEKKKVEQLKKKEAEEKKKAEelkKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEAlkkEAEEAKKA 1704

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366519 2848 AEMRPTGAKEKLRELELQRQRDEHKIR--QLQRTVQALEAKEEAAQRPEAERLQEERLGLERVRQ 2910
Cdd:PTZ00121  1705 EELKKKEAEEKKKAEELKKAEEENKIKaeEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769
PTZ00121 PTZ00121
MAEBL; Provisional
 172-876 3.62e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.24  E-value: 3.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  172 ELRAMLNGRHAQELALLRSRQQQElELAREQHAREQEEMR----LRCSQETAKLKEKLQSEMERNARAVESLKRDWESER 247
Cdd:PTZ00121  1150 DAKRVEIARKAEDARKAEEARKAE-DAKKAEAARKAEEVRkaeeLRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEA 1228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  248 GLCLENLRRELSAKHRSELENLQDQFkRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERCQYVQDL 327
Cdd:PTZ00121  1229 VKKAEEAKKDAEEAKKAEEERNNEEI-RKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  328 ----ELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDASARTPHGEELEQRErecgvqQQRRGR 403
Cdd:PTZ00121  1308 kkkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE------AKKKAD 1381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  404 RAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERREQRvgpslqpelAENHRchltawtS 483
Cdd:PTZ00121  1382 AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKK---------AEEAK-------K 1445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  484 SLEAQQQAGlvETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEvvarglglEAEHRLKLLLLQTELKEEMDvl 563
Cdd:PTZ00121  1446 ADEAKKKAE--EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE--------EAKKKADEAKKAAEAKKKAD-- 1513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  564 klENRNLHEKLQHEVCLKEDLERVKHSLVEdhREELKKANErlqlVKQELKDKEAEWKVASEDlKRKAEEELTLMLHDLK 643
Cdd:PTZ00121  1514 --EAKKAEEAKKADEAKKAEEAKKADEAKK--AEEKKKADE----LKKAEELKKAEEKKKAEE-AKKAEEDKNMALRKAE 1584

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  644 EQAEAEKQSVINKFELREiKMRQLQDQQAAQildlegslvEQQGRLRQLEHGLEAEECPRCGHCGQEPAGRVAPADQdwe 723
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYE-EEKKMKAEEAKK---------AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE--- 1651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  724 laTRRLREDCALQLMQAQSRFLKERKELTEKFTAEQD------ALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRR 797
Cdd:PTZ00121  1652 --LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDekkaaeALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK 1729

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366519  798 AEVEELKASVESERWALAEARVAELQTEHAAAISALEARHSallgslESRHLSEVQAMREEHRQALEQLRVDLEKQLQE 876
Cdd:PTZ00121  1730 IKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA------EEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1421-1724 7.26e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 7.26e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1421 KHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQaarprphgprvsdvelLQEKLREKSDGFNELVIKKELADRQVM 1500
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQ----------------LRKELEELSRQISALRKDLARLEAEVE 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1501 IQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKqmsnlllVSTLQSKLDEGRcpvppadscpegpe 1580
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-------IEQLKEELKALR-------------- 802

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1581 VQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEvlhlNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCV 1660
Cdd:TIGR02168  803 EALDELRAELTLLNEEAANLRERLESLERRIAATERR----LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366519 1661 SEQLEAQLAGMGSgalrevtydRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQE 1724
Cdd:TIGR02168  879 LNERASLEEALAL---------LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
PTZ00121 PTZ00121
MAEBL; Provisional
 2409-2909 9.99e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 9.99e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2409 QKGEQEPPDPGLDWRGEFLQAVQEAFGKEREMLRAELQPRPCGSAPGEHSSLLERLEKVvqEQEKSLEHLRASDRSSLLS 2488
Cdd:PTZ00121  1096 AFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRV--EIARKAEDARKAEEARKAE 1173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2489 EIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEhqlRRQVEllAYKVEQEKRI-----ASDVQKTlTEEQEKASS 2563
Cdd:PTZ00121  1174 DAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEE---RKAEE--ARKAEDAKKAeavkkAEEAKKD-AEEAKKAEE 1247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2564 VRKLLVVEQTVVRDLRSELR--------------ECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRA--ALQELESE 2627
Cdd:PTZ00121  1248 ERNNEEIRKFEEARMAHFARrqaaikaeearkadELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEA 1327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2628 RGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEAllaQERG 2707
Cdd:PTZ00121  1328 KKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKA---EEDK 1404

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2708 QLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHAllRKLKEEKSRAAELQARLEQVQRQQEADVQKRRA 2787
Cdd:PTZ00121  1405 KKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA--KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEA 1482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2788 ELEREKEVRAAQAREPGRCLRREGHASQQQAGLEPLQAGLAAQEGRK--DARRADvgpgradaEMRPTGAKEKLRELelq 2865
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaeEAKKAD--------EAKKAEEKKKADEL--- 1551

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1953366519 2866 rqRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERLGLERVR 2909
Cdd:PTZ00121  1552 --KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1186-1511 1.67e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 1.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1186 SSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLM 1265
Cdd:TIGR02168  671 SILERRREIEE----LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1266 LELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAGT 1345
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1346 pAPIAHEDSALRREVECLtQEQSEARKQSEKDRAALLSQMKVFEAELEEQLsrheacakqaEELSALRQQMAALDKHLRS 1425
Cdd:TIGR02168  827 -ESLERRIAATERRLEDL-EEQIEELSEDIESLAAEIEELEELIEELESEL----------EALLNERASLEEALALLRS 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1426 QRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARpRPHGPRVsDVELLQEKLREK-SDGFNELVIKKELADRQVMIQEE 1504
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLEL-RLEGLEV-RIDNLQERLSEEySLTLEEAEALENKIEDDEEEARR 972


                   ....*..
gi 1953366519 1505 EIRRLEE 1511
Cdd:TIGR02168  973 RLKRLEN 979
PTZ00121 PTZ00121
MAEBL; Provisional
 165-700 3.79e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.77  E-value: 3.79e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  165 EKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAVESLKRDWE 244
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  245 SERGLCL---ENLRRELSAKHRSELENLQDQFKRELSEQKAELEkifQAKNQAECALRTLEAQHEEALRQLREDLQSERC 321
Cdd:PTZ00121  1289 KKKADEAkkaEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAD---AAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK 1365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  322 QYVQDL---ELRLRDQEVEKQLElESLRASYAELKAqsqEEIRRLWSQLESPRPDRQDASARTPHGEELEQ-RERECGVQ 397
Cdd:PTZ00121  1366 AEAAEKkkeEAKKKADAAKKKAE-EKKKADEAKKKA---EEDKKKADELKKAAAAKKKADEAKKKAEEKKKaDEAKKKAE 1441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  398 QQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGErrEQRVGPSLQPELAENHRCH 477
Cdd:PTZ00121  1442 EAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKAD--EAKKAAEAKKKADEAKKAE 1519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  478 LTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEVV-----ARGLGLEAEHRLKLLLL 552
Cdd:PTZ00121  1520 EAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNmalrkAEEAKKAEEARIEEVMK 1599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  553 QTELKEEMDVLKL----ENRNLHEKLQHEVCLKEDLERVKHSLVEDHR--EELKKANERLQLVKQELKDKEAEWKVASED 626
Cdd:PTZ00121  1600 LYEEEKKMKAEEAkkaeEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKkaEELKKAEEENKIKAAEEAKKAEEDKKKAEE 1679

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366519  627 LKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREI-KMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEE 700
Cdd:PTZ00121  1680 AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKkKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEE 1754
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2467-2792 3.92e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 3.92e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2467 VVQEQEKSLEHLRAsDRSSLLSEIQALRAQLRMTHLQNQEKLQQLcAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRI 2546
Cdd:TIGR02168  671 SILERRREIEELEE-KIEELEEKIAELEKALAELRKELEELEEEL-EQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2547 ASDVQKTLTEEQEKASSVRKLLvveqtvvRDLRSELRECKQDNERLLASLGEAQKEVLQLRSvldskesnlraALQELES 2626
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERL-------EEAEEELAEAEAEIEELEAQIEQLKEELKALRE-----------ALDELRA 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2627 ERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQI---EASRCEALLA 2703
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAllnERASLEEALA 890

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2704 QERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPREspahhaLLRKLKEEKSRAAELQARLEQVQRQQEADVQ 2783
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG------LEVRIDNLQERLSEEYSLTLEEAEALENKIE 964


                   ....*....
gi 1953366519 2784 KRRAELERE 2792
Cdd:TIGR02168  965 DDEEEARRR 973
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1364-1726 1.10e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.15  E-value: 1.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1364 TQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFM---DEQAVEREHE 1440
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKrklEEKIRELEER 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1441 REEFQREIQRLEEQLRQAARPRPHGPRVSDVELLQEKLREKSDGfnelvIKKELADRQVMIQ--EEEIRRLEETNascrR 1518
Cdd:PRK03918   268 IEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELRE-----IEKRLSRLEEEINgiEERIKELEEKE----E 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1519 EAAQLREELERQRDAMKALQQDKEALQEkqmsnlllVSTLQSKLDEGRCPVppADSCPEGPEVQLEAVQRALQQRESEVL 1598
Cdd:PRK03918   339 RLEELKKKLKELEKRLEELEERHELYEE--------AKAKKEELERLKKRL--TGLTPEKLEKELEELEKAKEEIEEEIS 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1599 DLKEQLGKMKDDLVSKSDEVlhlnLELDAQSSRAAVSVRELQEEN-----ASLKAFLQNKEKEIMCVSEQLEAQLAgmgs 1673
Cdd:PRK03918   409 KITARIGELKKEIKELKKAI----EELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKELKEIEEKERKLRK---- 480

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1953366519 1674 gALREV--TYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEEL 1726
Cdd:PRK03918   481 -ELRELekVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKL 534
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 580-1063 1.57e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 1.57e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  580 LKEDLERVKHSLVEDhREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLmlhdlkEQAEAEKQSVINKFEL 659
Cdd:COG1196    314 LEERLEELEEELAEL-EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA------EAELAEAEEELEELAE 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  660 REIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcGQEPAGRVAPADQDWELATRRLREDCALQLMQ 739
Cdd:COG1196    387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE-------EALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  740 AQSRFLKERKELTEKFTAEQDALLQEAQEKHAcdmrllqerhqqhVLSLTAQLEARRRAEVEELKASVESERWALAEARV 819
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAA-------------RLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  820 AELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQlRVDLEKQLQEKEASHPTPLTQALEKHPLSHGQE 899
Cdd:COG1196    527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG-RATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  900 LPPVEGGLRTQTSSGQLEGVKAPVPP----------------EVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQLHC 963
Cdd:COG1196    606 SDLREADARYYVLGDTLLGRTLVAARleaalrravtlagrlrEVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  964 QEEPEVLEcpsepFLEQQILQpkgefESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQILSLS 1043
Cdd:COG1196    686 ERLAEEEL-----ELEEALLA-----EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

                          490       500
                   ....*....|....*....|
gi 1953366519 1044 HEVEERRRDLEQLQQRRERE 1063
Cdd:COG1196    756 LPEPPDLEELERELERLERE 775
PTZ00121 PTZ00121
MAEBL; Provisional
 2528-2911 1.82e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 1.82e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2528 QLRRQVELLAYkvEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRdlRSELRECKQDNERLLASLGEAQKEVLQLR 2607
Cdd:PTZ00121  1083 AKEDNRADEAT--EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARK--AEEARKAEDARKAEEARKAEDAKRVEIAR 1158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2608 SVLDSKESNLRAALQELESERGKERALQSR-LEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDN 2686
Cdd:PTZ00121  1159 KAEDARKAEEARKAEDAKKAEAARKAEEVRkAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKD 1238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2687 LQKELQIEASRC-EALLAQERGQLSELQRSLEAEKGRSLELAAALR--HERLLTEQLSRGPRESPAHHAllRKLKEEKSR 2763
Cdd:PTZ00121  1239 AEEAKKAEEERNnEEIRKFEEARMAHFARRQAAIKAEEARKADELKkaEEKKKADEAKKAEEKKKADEA--KKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2764 AAELQARLEQVQRQqeADVQKRRAElEREKEVRAAQAREPGRCLRREGHASQQQAG-LEPLQAGLAAQEGRKDA---RRA 2839
Cdd:PTZ00121  1317 ADEAKKKAEEAKKK--ADAAKKKAE-EAKKAAEAAKAEAEAAADEAEAAEEKAEAAeKKKEEAKKKADAAKKKAeekKKA 1393

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366519 2840 DVGPGRADAEMRPTgakEKLRELELQRQRDEHKIRQLQRTVQALEAK---EEAAQRPEAERLQEERLGLERVRQQ 2911
Cdd:PTZ00121  1394 DEAKKKAEEDKKKA---DELKKAAAAKKKADEAKKKAEEKKKADEAKkkaEEAKKADEAKKKAEEAKKAEEAKKK 1465
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 251-872 1.83e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.83e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  251 LENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERcqyvqdlELR 330
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY-------ELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  331 LRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQlesprpDRQDASARTPhgEELEQRERECGVQQQRRGRRAEQESE 410
Cdd:COG1196    295 AELARLEQDIARLEERRRELEERLEELEEELAELEE------ELEELEEELE--ELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  411 LGQSPEGAAERGREDPVLLEQRLQDATEEPSLEsggigpSSMREGERREQRvgpslqpelAENHRCHLTAWTSSLEAQQQ 490
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELA------AQLEELEEAEEA---------LLERLERLEEELEELEEALA 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  491 AGLVETQESEGEQREglsegpgqeltqvpvpcAQGTALKVDTEVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNL 570
Cdd:COG1196    432 ELEEEEEEEEEALEE-----------------AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  571 heklqhevcLKEDLERVKHSLVEDHREELKKANERL--QLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEA 648
Cdd:COG1196    495 ---------LLLEAEADYEGFLEGVKAALLLAGLRGlaGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  649 EKQSVINKFE-LREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcGQEPAGRVAPADQDWELATR 727
Cdd:COG1196    566 LKAAKAGRATfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVL-------GDTLLGRTLVAARLEAALRR 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  728 RLREDCALQLMQAQSRFLKERKELTEKFTAEQDALLQEAQEKhacdMRLLQERHQQHVLSLTAQLEARRRAEVEELKASV 807
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE----LEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366519  808 ESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAmREEHRQALEQLRVDLEK 872
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD-LEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1218-1900 2.10e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 2.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1218 QLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEH 1297
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1298 GLAEELEGLRQQLQQAAQQQAELKEENSAL------WSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQSEA- 1370
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESRLEELeeqletLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELl 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1371 RKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQR 1450
Cdd:TIGR02168  428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG 507

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1451 LEEQLRQAARPRPHGPRVSDVELLQEK--------LREKSDgfNELVIKKELADRQV--MIQEEEIRR--LEETNASCRR 1518
Cdd:TIGR02168  508 VKALLKNQSGLSGILGVLSELISVDEGyeaaieaaLGGRLQ--AVVVENLNAAKKAIafLKQNELGRVtfLPLDSIKGTE 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1519 EAAQLREELERQRDAMKALQQDKEALQEKQ------MSNLLLVSTLQSKLD-------EGRCPVPPADSCPEGPEVQLEA 1585
Cdd:TIGR02168  586 IQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsylLGGVLVVDDLDNALElakklrpGYRIVTLDGDLVRPGGVITGGS 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1586 VQRA--LQQRESEVLDLKEQLGKMKDDLvsksdevlhlnLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQ 1663
Cdd:TIGR02168  666 AKTNssILERRREIEELEEKIEELEEKI-----------AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1664 LEAqlAGMGSGALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAE---EMEQLHEVIERLQEELSLgapavpaavdce 1740
Cdd:TIGR02168  735 LAR--LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKA------------ 800

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1741 lpavpapavgpEALAAAGAASRLFAEQEHRHGQALEalQQRLQAAEEAAAGQLAELERSAALREAEVQAMASQIQAFEAA 1820
Cdd:TIGR02168  801 -----------LREALDELRAELTLLNEEAANLRER--LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1821 LRAKEARLAERDLEIDAMKRQKLAHSAELETilaaFSRFRRTLERQPLAAEDeppELQRLRVQCVRLSRQLQVLNQRFLR 1900
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEE----LSEELRELESKRSELRR---ELEELREKLAQLELRLEGLEVRIDN 940
PTZ00121 PTZ00121
MAEBL; Provisional
 245-1080 5.38e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 5.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  245 SERGLCLENLRRELSAKHRS-ELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERCQY 323
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNrADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  324 VQDLELRLRDQEVEKQLELESLR----ASYAElKAQSQEEIRRlwsqlesprpdrqdasartphGEELEQRERecgVQQQ 399
Cdd:PTZ00121  1148 AEDAKRVEIARKAEDARKAEEARkaedAKKAE-AARKAEEVRK---------------------AEELRKAED---ARKA 1202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  400 RRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERREQRVGPSLQPELAENHRchlt 479
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEAR---- 1278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  480 AWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEVVARglGLEAEHRLKLLLLQTELKEE 559
Cdd:PTZ00121  1279 KADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKK--KAEEAKKAAEAAKAEAEAAA 1356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  560 MDVLKLENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVAsEDLKRKAEEELTlmL 639
Cdd:PTZ00121  1357 DEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA-DEAKKKAEEKKK--A 1433

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  640 HDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEECPRcghcGQEPAGRVAPAD 719
Cdd:PTZ00121  1434 DEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKK----KADEAKKAAEAK 1509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  720 QDWELATRRLREDCALQLMQA-QSRFLKERKELTEKFTAEQ---DALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEAR 795
Cdd:PTZ00121  1510 KKADEAKKAEEAKKADEAKKAeEAKKADEAKKAEEKKKADElkkAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA 1589

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  796 RRAEVEELKASVESERWALAEarvaELQTEHAAAISALEARHSallgSLESRHLSEVQAMREEHRQALEQLRVDLEKQL- 874
Cdd:PTZ00121  1590 EEARIEEVMKLYEEEKKMKAE----EAKKAEEAKIKAEELKKA----EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKi 1661

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  875 -QEKEASHPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQ-----EGAPVPAEvEAQRPA- 947
Cdd:PTZ00121  1662 kAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEElkkaeEENKIKAE-EAKKEAe 1740

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  948 ----LLAELRQETGK----QQLHCQEEPEVLECPSEpflEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKE 1019
Cdd:PTZ00121  1741 edkkKAEEAKKDEEEkkkiAHLKKEEEKKAEEIRKE---KEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEG 1817

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953366519 1020 SLFLQlQEKNNQILQLKEQILSlSHEVEERRRDLEQLQQRRERENQEGTNLISMLKSDADL 1080
Cdd:PTZ00121  1818 NLVIN-DSKEMEDSAIKEVADS-KNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDL 1876
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1363-1715 9.74e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.77  E-value: 9.74e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1363 LTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALD---KHLRSQRQFMD--EQAVER 1437
Cdd:COG4717     51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEaelEELREELEKLEklLQLLPL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1438 EHEREEFQREIQRLEEQLRQA-ARPRPHGPRVSDVELLQEKLREKSDGFNELVIKKELADRQVMIQ-EEEIRRLEETNAS 1515
Cdd:COG4717    131 YQELEALEAELAELPERLEELeERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDlAEELEELQQRLAE 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1516 CRREAAQLREELERQRDAMKALQQDKEALQEKQ-----------MSNLLLVSTLQSKLDEGRCPVPPA------------ 1572
Cdd:COG4717    211 LEEELEEAQEELEELEEELEQLENELEAAALEErlkearlllliAAALLALLGLGGSLLSLILTIAGVlflvlgllallf 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1573 --------DSCPEGPEVQLEAVQRALQQRE----------------SEVLDLKEQLGKMKDDLVSKSD-----EVLHLNL 1623
Cdd:COG4717    291 lllarekaSLGKEAEELQALPALEELEEEEleellaalglppdlspEELLELLDRIEELQELLREAEEleeelQLEELEQ 370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1624 ELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSGALREVTYDRSSEIEELRSIIENLRENQQR 1703
Cdd:COG4717    371 EIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEE 450

                          410
                   ....*....|....*
gi 1953366519 1704 LQKEKAE---EMEQL 1715
Cdd:COG4717    451 LREELAEleaELEQL 465
PTZ00121 PTZ00121
MAEBL; Provisional
 1213-1725 1.62e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 1.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1213 LDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENA-----ARTRLMLELHQAQGIIEGFKEEKASLQE 1287
Cdd:PTZ00121  1214 AEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEArmahfARRQAAIKAEEARKADELKKAEEKKKAD 1293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1288 ALCRQEtaEHGLAEEL----------EGLRQQLQQAAQQQAELKEEnsALWSQKEASAAEAEAREAGTPAPIAHEDS-AL 1356
Cdd:PTZ00121  1294 EAKKAE--EKKKADEAkkkaeeakkaDEAKKKAEEAKKKADAAKKK--AEEAKKAAEAAKAEAEAAADEAEAAEEKAeAA 1369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1357 RREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELE-EQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAV 1435
Cdd:PTZ00121  1370 EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKaDELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA 1449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1436 EREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDVELLQEKLREKSDGFNELViKKELADRQVmiqeEEIRRLEEtnas 1515
Cdd:PTZ00121  1450 KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAK-KAAEAKKKA----DEAKKAEE---- 1520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1516 cRREAAQLRE-ELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQsKLDEGRcpvpPADSCPEGPEVQLEAVQRALQQRE 1594
Cdd:PTZ00121  1521 -AKKADEAKKaEEAKKADEAKKAEEKKKADELKKAEELKKAEEKK-KAEEAK----KAEEDKNMALRKAEEAKKAEEARI 1594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1595 SEVLDLKEQLGKMKDDLVSKSDEVLHLNLEL-DAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAgmgs 1673
Cdd:PTZ00121  1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA---- 1670

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1953366519 1674 galrevtYDRSSEIEELRSIIENLRENQQRLQKEkAEEMEQLHEVIERLQEE 1725
Cdd:PTZ00121  1671 -------EEDKKKAEEAKKAEEDEKKAAEALKKE-AEEAKKAEELKKKEAEE 1714
PTZ00121 PTZ00121
MAEBL; Provisional
 1346-2072 1.66e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 1.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1346 PAPIAHEDSALRREVEclTQEQSEARKQSEKDRaallsqmKVFEAELEEQLSRHEAcAKQAEELSALRQQMAALD-KHLR 1424
Cdd:PTZ00121  1074 PSYKDFDFDAKEDNRA--DEATEEAFGKAEEAK-------KTETGKAEEARKAEEA-KKKAEDARKAEEARKAEDaRKAE 1143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1425 SQRQFMDEQAVEREHEREEFQR-EIQRLEEQLRQAARPRphgpRVSDVELLQEkLREKSDgfnelVIKKELADRQvmiqe 1503
Cdd:PTZ00121  1144 EARKAEDAKRVEIARKAEDARKaEEARKAEDAKKAEAAR----KAEEVRKAEE-LRKAED-----ARKAEAARKA----- 1208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1504 EEIRRLEETNascRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRCPVPPADSCPEGPEV-- 1581
Cdd:PTZ00121  1209 EEERKAEEAR---KAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELkk 1285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1582 -----QLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELD--AQSSRAAVSVRELQEENASLKAFLQNKE 1654
Cdd:PTZ00121  1286 aeekkKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKkkAEEAKKAAEAAKAEAEAAADEAEAAEEK 1365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1655 KEimcvSEQLEAQLAGMGSGALREVTyDRSSEIEELRSIIENLRENQQRLQKEKAEE--MEQLHEVIERLQEELSLGAPA 1732
Cdd:PTZ00121  1366 AE----AAEKKKEEAKKKADAAKKKA-EEKKKADEAKKKAEEDKKKADELKKAAAAKkkADEAKKKAEEKKKADEAKKKA 1440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1733 VPAAVDCELPAVPAPAVGPEALAAAGAASRLFAE-----QEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEV 1807
Cdd:PTZ00121  1441 EEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEakkkaEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE 1520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1808 QAMASQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELetilaafsrfRRTLERQPLAAEDEPPELQRLRVQcvrl 1887
Cdd:PTZ00121  1521 AKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEE----------KKKAEEAKKAEEDKNMALRKAEEA---- 1586

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1888 srqlqvlnqrflrcqkeadkQQARGARLRPRGARGLQGPGPRAEEASRDEASQQDVDSRQVASATQGQVRDPQNAVNDDL 1967
Cdd:PTZ00121  1587 --------------------KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK 1646

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1968 QPAElpvtsgppGLLKQDSVMSVLAVCQRQLESELLLLKNEMHLRTEDRGKAPARMKNKENllEDRQLQKVGliSQVKEL 2047
Cdd:PTZ00121  1647 KKAE--------ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE--EAKKAEELK--KKEAEE 1714

                          730       740
                   ....*....|....*....|....*
gi 1953366519 2048 QEKLNHLVRSVNFQNIETEDFKSQQ 2072
Cdd:PTZ00121  1715 KKKAEELKKAEEENKIKAEEAKKEA 1739
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1142-1712 1.72e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 53.96  E-value: 1.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1142 LEETWPGSEAALLELDRSLPECVEMPSEAEISSHIC----ESFFMSPESSLEYE---QPIRRIYQSLGLAVEGLLeLALD 1214
Cdd:pfam05483  122 IQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCnllkETCARSAEKTKKYEyerEETRQVYMDLNNNIEKMI-LAFE 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1215 STR-QLEEAR-----QIHSRFEKEFSCKNEETAQVVRKQQQ----LLERLEEENAARTrLMLELHQAQGIIEGFKEEKAS 1284
Cdd:pfam05483  201 ELRvQAENARlemhfKLKEDHEKIQHLEEEYKKEINDKEKQvsllLIQITEKENKMKD-LTFLLEESRDKANQLEEKTKL 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1285 LQEALCRQETAEHGLAEELEGLRQQLQQAAQQQA--------------ELKEENSALWSQKEASAAEAEAREAGTPAPIA 1350
Cdd:pfam05483  280 QDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKaleedlqiatkticQLTEEKEAQMEELNKAKAAHSFVVTEFEATTC 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1351 HEDSALRREVECLTQEQSE--------ARKQSE--------KDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQ 1414
Cdd:pfam05483  360 SLEELLRTEQQRLEKNEDQlkiitmelQKKSSEleemtkfkNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQ 439

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1415 QMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDVELLQEK--LREKSDGFNELviKK 1492
Cdd:pfam05483  440 ELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKelTQEASDMTLEL--KK 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1493 ELADRQVMIQEEE-----IRRLEETNASCRREAAQLREELERQRDAMKAlQQDKEALQEKQMSNLLLVSTLQSKLDEGRC 1567
Cdd:pfam05483  518 HQEDIINCKKQEErmlkqIENLEEKEMNLRDELESVREEFIQKGDEVKC-KLDKSEENARSIEYEVLKKEKQMKILENKC 596

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1568 pvppadscpEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSV----RELQEEN 1643
Cdd:pfam05483  597 ---------NNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIdnyqKEIEDKK 667

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366519 1644 ASLKAFLQNKEKEIMCVSEQLEAQlagmgsgalREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEM 1712
Cdd:pfam05483  668 ISEEKLLEEVEKAKAIADEAVKLQ---------KEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSEL 727
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1442-1726 1.76e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.30  E-value: 1.76e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1442 EEFQREIQRLEEQLRQAARPRPHGPRVSDvelLQEKLREKSdgFNELVIKKELADRQVMIQEEEIRRLEETNASCRREAA 1521
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKAERYQA---LLKEKREYE--GYELLKEKEALERQKEAIERQLASLEEELEKLTEEIS 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1522 QLREELERQRDAMKALQQDKEALQEKQMSnlllvsTLQSKLDEgrcpvppadscpegPEVQLEAVQRALQQRESEVLDLK 1601
Cdd:TIGR02169  262 ELEKRLEEIEQLLEELNKKIKDLGEEEQL------RVKEKIGE--------------LEAEIASLERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1602 EQLGKMKDDLVSKSDEVLHLNLELDAQssraAVSVRELQEENASLKAFLQNKEKEImcvsEQLEAQLAgmgsgALREVTY 1681
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELEREIEEE----RKRRDKLTEEYAELKEELEDLRAEL----EEVDKEFA-----ETRDELK 388

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1953366519 1682 DRSSEIEELRSIIENLRENQQRLQKEK---AEEMEQLHEVIERLQEEL 1726
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELqrlSEELADLNAAIAGIEAKI 436
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2456-2910 2.52e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.77  E-value: 2.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2456 EHSSLLERLEKVVQEQEKsLEHLRASDRSSLL-SEIQALRAQLRmthlQNQEKLQQLCAALTSAEARGSRQEHQLR---- 2530
Cdd:COG4913    263 RYAAARERLAELEYLRAA-LRLWFAQRRLELLeAELEELRAELA----RLEAELERLEARLDALREELDELEAQIRgngg 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2531 RQVELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELREckqdnerLLASLGEAQKEVLQLRSVL 2610
Cdd:COG4913    338 DRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA-------LLEALEEELEALEEALAEA 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2611 DSKESNLRAALQELESERGKERALQSRLEEAQLQHLQR-EGQSSKTLEEL----------------RASLEK---QFAQS 2670
Cdd:COG4913    411 EAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAlAEALGLDEAELpfvgelievrpeeerwRGAIERvlgGFALT 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2671 sqLCVALKHEQTAK---DNLQKELQIEASRCEALLAQERGQ--------------LSELQRSLEAEKGRSLELA-----A 2728
Cdd:COG4913    491 --LLVPPEHYAAALrwvNRLHLRGRLVYERVRTGLPDPERPrldpdslagkldfkPHPFRAWLEAELGRRFDYVcvdspE 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2729 AL-RHERLLTEQ-LSRGPRESPAH--------------------HALLRKLKEEKSRAAELQARLEQVQRQQEAdVQKRR 2786
Cdd:COG4913    569 ELrRHPRAITRAgQVKGNGTRHEKddrrrirsryvlgfdnraklAALEAELAELEEELAEAEERLEALEAELDA-LQERR 647

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2787 AELEREKEVRAAQAREPGrcLRREGHASQQQ-AGLEPLQAGLAAQEGRKDARRADvgpgRADAEMRPTGAKEKLRELELQ 2865
Cdd:COG4913    648 EALQRLAEYSWDEIDVAS--AEREIAELEAElERLDASSDDLAALEEQLEELEAE----LEELEEELDELKGEIGRLEKE 721

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 1953366519 2866 RQRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERLGLERVRQ 2910
Cdd:COG4913    722 LEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERE 766
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1216-1897 4.45e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.76  E-value: 4.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1216 TRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERL----EEENAARTRLMLELH----QAQGIIEGFKEEKASLQE 1287
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEaeiaSLERSIAEKERELEDAEE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1288 ALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALwSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQ 1367
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL-KEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1368 SE-----ARKQSEKDR------------AALLSQMKVFEAELEEqlsRHEACAKQAEELSALRQQMAALDKHLRSQRQfm 1430
Cdd:TIGR02169  402 NElkrelDRLQEELQRlseeladlnaaiAGIEAKINELEEEKED---KALEIKKQEWKLEQLAADLSKYEQELYDLKE-- 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1431 DEQAVEREheREEFQREIQRLEEQLRQAARPRPHGPRVSDVellqekLREKSDGFNELVikkeladRQVMIQEEEIRRLE 1510
Cdd:TIGR02169  477 EYDRVEKE--LSKLQRELAEAEAQARASEERVRGGRAVEEV------LKASIQGVHGTV-------AQLGSVGERYATAI 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1511 ETNASCRREA--------AQLREELERQRDA----------MKALQQDKEALQEK------------------------- 1547
Cdd:TIGR02169  542 EVAAGNRLNNvvveddavAKEAIELLKRRKAgratflplnkMRDERRDLSILSEDgvigfavdlvefdpkyepafkyvfg 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1548 -------------QMSNLLLVsTLQSKLDEgrcpvpPADSCPEGPEVQLEAVQRALQQREsEVLDLKEQLGKMKDDLVSK 1614
Cdd:TIGR02169  622 dtlvvedieaarrLMGKYRMV-TLEGELFE------KSGAMTGGSRAPRGGILFSRSEPA-ELQRLRERLEGLKRELSSL 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1615 SDEVLHLNLELDAQSSRAAVSVRELQEenaslkaflqnKEKEImcvsEQLEAQLAgmgsgALREVTYDRSSEIEELRSII 1694
Cdd:TIGR02169  694 QSELRRIENRLDELSQELSDASRKIGE-----------IEKEI----EQLEQEEE-----KLKERLEELEEDLSSLEQEI 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1695 ENLRENQQRLQKEKAEEMEQLHEvierLQEELSlgapavpaavdcELPAVPAPAVGPEALAAAGAASRLFAEQEHRhGQA 1774
Cdd:TIGR02169  754 ENVKSELKELEARIEELEEDLHK----LEEALN------------DLEARLSHSRIPEIQAELSKLEEEVSRIEAR-LRE 816

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1775 LEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEIdamkrqklahsAELETILA 1854
Cdd:TIGR02169  817 IEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL-----------RDLESRLG 885

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1953366519 1855 AFSRFRRTLERQPLAAEDEPPEL----QRLRVQCVRLSRQLQVLNQR 1897
Cdd:TIGR02169  886 DLKKERDELEAQLRELERKIEELeaqiEKKRKRLSELKAKLEALEEE 932
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1236-1724 5.38e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 5.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1236 KNEETAQVVRKQQQLLERLEEENA-ARTRLMLELHQAQGI---IEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQ 1311
Cdd:PRK02224   273 EREELAEEVRDLRERLEELEEERDdLLAEAGLDDADAEAVearREELEDRDEELRDRLEECRVAAQAHNEEAESLREDAD 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1312 QAAQQQAELKEENSALWSqkeasaaeaeareagtpapiahEDSALRREVECLTQEQSEARKQSEKDRAALLSQmkvfEAE 1391
Cdd:PRK02224   353 DLEERAEELREEAAELES----------------------ELEEAREAVEDRREEIEELEEEIEELRERFGDA----PVD 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1392 LEEQLSRHEACakqAEELSALRQQMAALDKHLRSQRQFMDE--------------QAV----------EREHEREEFQRE 1447
Cdd:PRK02224   407 LGNAEDFLEEL---REERDELREREAELEATLRTARERVEEaealleagkcpecgQPVegsphvetieEDRERVEELEAE 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1448 IQRLEEQlrqaarprpHGPRVSDVELLqEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREEL 1527
Cdd:PRK02224   484 LEDLEEE---------VEEVEERLERA-EDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEA 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1528 ERQRDAMKALQQDKEALQEKqmsnlllVSTLQSKLDEGRCPVPPADSCPEGPEvQLEAVQRALQQRESEVLDLKEQLGKM 1607
Cdd:PRK02224   554 EEKREAAAEAEEEAEEAREE-------VAELNSKLAELKERIESLERIRTLLA-AIADAEDEIERLREKREALAELNDER 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1608 KDDLVSKSDEVLHLNLELDAQssraavSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSgalrevtydRSSEI 1687
Cdd:PRK02224   626 RERLAEKRERKRELEAEFDEA------RIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGA---------VENEL 690

                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 1953366519 1688 EELrsiiENLRENQQRLQkEKAEEMEQLHEVIERLQE 1724
Cdd:PRK02224   691 EEL----EELRERREALE-NRVEALEALYDEAEELES 722
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1367-1546 8.04e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 8.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1367 QSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEEL----SALRQQMAALDKHLRSQRQFMDEQAVEREHERE 1442
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALerriAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1443 EFQREIQRLEEQLRQAARPRPHGP--------------------------RVSDVELLQEKLREKSDGFNELVIKKELAD 1496
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPlalllspedfldavrrlqylkylapaRREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1497 RQVMIQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQE 1546
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2576-2897 8.51e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 8.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2576 RDLRSELRECKQdnERLLASLGEAQKEVLQLRSVLDSKESNLrAALQELESERGKE-RALQSRLEEAQLQHLQREGQSSK 2654
Cdd:TIGR02169  214 QALLKEKREYEG--YELLKEKEALERQKEAIERQLASLEEEL-EKLTEEISELEKRlEEIEQLLEELNKKIKDLGEEEQL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2655 TLEELRASLEKQFAQssqlcvaLKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHER 2734
Cdd:TIGR02169  291 RVKEKIGELEAEIAS-------LERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2735 LLTEQL-SRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQARepgrclrREGHA 2813
Cdd:TIGR02169  364 EELEDLrAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAG-------IEAKI 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2814 SQQQAGLEPLQAGLAAQEGRKDARRADVGPgradaemrptgAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRP 2893
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSK-----------YEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505


                   ....
gi 1953366519 2894 EAER 2897
Cdd:TIGR02169  506 VRGG 509
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1389-1727 9.42e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 9.42e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1389 EAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQfmdeQAVEREheREEFQREIQRLEEQLRQaarprphgprv 1468
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEK----EALERQ--KEAIERQLASLEEELEK----------- 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1469 sdvelLQEKLREKSDGFNELVIKKELADRQVM-IQEEEIRRLeetnascRREAAQLREELERQRDAMKALQQDKEALQEK 1547
Cdd:TIGR02169  256 -----LTEEISELEKRLEEIEQLLEELNKKIKdLGEEEQLRV-------KEKIGELEAEIASLERSIAEKERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1548 QMSNLLLVSTLQSKLdegrcpvppadscpEGPEVQLEAVQRALQQRESEVLDLKEQLgkmkDDLVSKSDEVLHLNLELDA 1627
Cdd:TIGR02169  324 LAKLEAEIDKLLAEI--------------EELEREIEEERKRRDKLTEEYAELKEEL----EDLRAELEEVDKEFAETRD 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1628 QSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQ---LEAQLAGMgSGALREVTYDRSSEIEELRSIIENLRENQQRL 1704
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEEladLNAAIAGI-EAKINELEEEKEDKALEIKKQEWKLEQLAADL 464

                          330       340
                   ....*....|....*....|...
gi 1953366519 1705 QKEKaEEMEQLHEVIERLQEELS 1727
Cdd:TIGR02169  465 SKYE-QELYDLKEEYDRVEKELS 486
mukB PRK04863
chromosome partition protein MukB;
2462-2904 1.11e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 51.50  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2462 ERLEKVVQEQEKSlehlrASDRSSLLSEIQALRA--QLRMTHLQNQEKLQQLCAALTSAEARgsrqehqLRRQVELLAyk 2539
Cdd:PRK04863   307 YRLVEMARELAEL-----NEAESDLEQDYQAASDhlNLVQTALRQQEKIERYQADLEELEER-------LEEQNEVVE-- 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2540 VEQEKRIASDVQKTLTEEQekassvrkllvveqtvVRDLRSELRECKQdnerllaSLGEAQKEVLQLR---SVLDSKESN 2616
Cdd:PRK04863   373 EADEQQEENEARAEAAEEE----------------VDELKSQLADYQQ-------ALDVQQTRAIQYQqavQALERAKQL 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2617 LRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRaslekQFAQSSQLCVALKHE-------QTAKDNLQK 2689
Cdd:PRK04863   430 CGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHS-----QFEQAYQLVRKIAGEvsrseawDVARELLRR 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2690 --ELQIEASRCEALlaqeRGQLSELQRSLEAEKgrslelaaalRHERLLTE---QLSRGP-------RESPAHHALLRKL 2757
Cdd:PRK04863   505 lrEQRHLAEQLQQL----RMRLSELEQRLRQQQ----------RAERLLAEfckRLGKNLddedeleQLQEELEARLESL 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2758 KEEKSRAAELQARLEQVQRQQEADVQKRRAeleREKEVRAAQARepgrclrreghasqqqagLEPLQAglaaQEGRKDAR 2837
Cdd:PRK04863   571 SESVSEARERRMALRQQLEQLQARIQRLAA---RAPAWLAAQDA------------------LARLRE----QSGEEFED 625

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366519 2838 RADVgpgraDAEMRPTgaKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAaqrpEAERLQE--ERLG 2904
Cdd:PRK04863   626 SQDV-----TEYMQQL--LERERELTVERDELAARKQALDEEIERLSQPGGS----EDPRLNAlaERFG 683
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1355-1911 1.42e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.38  E-value: 1.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1355 ALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRH--------EACAKQAEELSALRQQMAALDKHLRSQ 1426
Cdd:pfam12128  287 ELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHgafldadiETAAADQEQLPSWQSELENLEERLKAL 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1427 RQfmDEQAVEREHER------EEFQREIQRLEEQL--RQAARPRPHGPRVSDVELLQEKLREKSDGFNelvikkeladRQ 1498
Cdd:pfam12128  367 TG--KHQDVTAKYNRrrskikEQNNRDIAGIKDKLakIREARDRQLAVAEDDLQALESELREQLEAGK----------LE 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1499 VMIQEEEIR-RLEETNAscRREAAQLREELERQrdaMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRCPVPPADSCPE 1577
Cdd:pfam12128  435 FNEEEYRLKsRLGELKL--RLNQATATPELLLQ---LENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALR 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1578 GPEVQLEAVQRALQQRE---------------SEVLDLKEQLGKMKD-------DLVSKSDE--------VLHLNLELDA 1627
Cdd:pfam12128  510 QASRRLEERQSALDELElqlfpqagtllhflrKEAPDWEQSIGKVISpellhrtDLDPEVWDgsvggelnLYGVKLDLKR 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1628 -QSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLeaqlaGMGSGALREVtydrSSEIEELRSIIENLRENQQRLQK 1706
Cdd:pfam12128  590 iDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQL-----VQANGELEKA----SREETFARTALKNARLDLRRLFD 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1707 EKAEEMEQLHEVIERLQEElslgapAVPAAVDCElpavpapavgpeaLAAAGAASRLFAEQEHRHGQALEALQQRLQAAE 1786
Cdd:pfam12128  661 EKQSEKDKKNKALAERKDS------ANERLNSLE-------------AQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQ 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1787 EAAAGQLAELERSAALREAEVQAMASQIQAFE-------AALRAKEARLAERDLEIDAMKRqKLAHSAELETILAAFSRF 1859
Cdd:pfam12128  722 VVEGALDAQLALLKAAIAARRSGAKAELKALEtwykrdlASLGVDPDVIAKLKREIRTLER-KIERIAVRRQEVLRYFDW 800

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1953366519 1860 RR---TLERQPLAAEDEPPE--LQRLRVQCVRLSRQLQVLNQRFLRCQKEADKQQAR 1911
Cdd:pfam12128  801 YQetwLQRRPRLATQLSNIEraISELQQQLARLIADTKLRRAKLEMERKASEKQQVR 857
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 735-1548 1.98e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.83  E-value: 1.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  735 LQLMQAQSRFLKERKEL-TEKFTAEQDALLQEAQEKHACDMRLLQE--RHQQHVLSLTAQLEARRrAEVEELKASVESer 811
Cdd:TIGR02168  202 LKSLERQAEKAERYKELkAELRELELALLVLRLEELREELEELQEElkEAEEELEELTAELQELE-EKLEELRLEVSE-- 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  812 walAEARVAELQTE---HAAAISALEAR---HSALLGSLEsRHLSEVQAMREEHRQALEQLRVDLEkQLQEKEASHPTPL 885
Cdd:TIGR02168  279 ---LEEEIEELQKElyaLANEISRLEQQkqiLRERLANLE-RQLEELEAQLEELESKLDELAEELA-ELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  886 TQALEKHPLSHgQELPPVEGGLRTQTSsgQLEGVKApvppEVQGAQQEGAPVPAEVEAQRpallAELRQETGKQQLHCQE 965
Cdd:TIGR02168  354 ESLEAELEELE-AELEELESRLEELEE--QLETLRS----KVAQLELQIASLNNEIERLE----ARLERLEDRRERLQQE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  966 EPEVLECPSEPFLEqqilqpkgefESEKKVALHEKEIHGLecaqaqslyQKEKESLFLQLQEKNNQILQLKEQILSLSHE 1045
Cdd:TIGR02168  423 IEELLKKLEEAELK----------ELQAELEELEEELEEL---------QEELERLEEALEELREELEEAEQALDAAERE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1046 VEERRRDLEQLQQRRERENQEGTNLISMLKSDADLSDrerralrdalrrLLSLFGEMLKVA----IALKSRISERVG-LC 1120
Cdd:TIGR02168  484 LAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSG------------ILGVLSELISVDegyeAAIEAALGGRLQaVV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1121 LEDEDppgawpsgQALSAAPVLEETWPGsEAALLELDRSLPECVEMPSEAEISSHICesfFMSPESSLEYEQP-IRRIYQ 1199
Cdd:TIGR02168  552 VENLN--------AAKKAIAFLKQNELG-RVTFLPLDSIKGTEIQGNDREILKNIEG---FLGVAKDLVKFDPkLRKALS 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1200 SL--GLAVEGLLELALDSTRQLEEARQIHS----RFEKEFSC--KNEETAQVVRKQQQLLERLEEENAARTRLMLELHQA 1271
Cdd:TIGR02168  620 YLlgGVLVVDDLDNALELAKKLRPGYRIVTldgdLVRPGGVItgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKA 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1272 ----QGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAgtpa 1347
Cdd:TIGR02168  700 laelRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE---- 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1348 piahEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQR 1427
Cdd:TIGR02168  776 ----ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1428 qfmdEQAVEREHEREEFQREIQRLEEQL-----RQAARPRPHGPRVSDVELLQEKLREKSDGFNELvikKELADRQVMIQ 1502
Cdd:TIGR02168  852 ----EDIESLAAEIEELEELIEELESELeallnERASLEEALALLRSELEELSEELRELESKRSEL---RRELEELREKL 924

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*.
gi 1953366519 1503 EEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQ 1548
Cdd:TIGR02168  925 AQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEA 970
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2461-2672 2.08e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 2.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2461 LERLEKVVQEQEKSLEHLRAsDRSSLLSEIQALRAQLRMTHLQ---NQEKLQQLCAALTSAEARGSRQEHQLRRQVELLA 2537
Cdd:COG4942     29 LEQLQQEIAELEKELAALKK-EEKALLKQLAALERRIAALARRiraLEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2538 YKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDskesNL 2617
Cdd:COG4942    108 ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA----EL 183

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1953366519 2618 RAALQELESERGKERALQSRLE---EAQLQHLQREGQSSKTLEELRASLEKQFAQSSQ 2672
Cdd:COG4942    184 EEERAALEALKAERQKLLARLEkelAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 137-875 3.62e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.84  E-value: 3.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  137 SLELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQeLALLRSRQQQELELAREQHAREQEEMRLRCSQ 216
Cdd:pfam12128  252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQ-WKEKRDELNGELSAADAAVAKDRSELEALEDQ 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  217 ETAKLKEKLQSEMERNARAvESLKRDWE--SERGLCLENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQA 294
Cdd:pfam12128  331 HGAFLDADIETAAADQEQL-PSWQSELEnlEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQ 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  295 ECALRTLEAQHEEALRQLREDLQSErcqyVQDLELRLRDQEVEKQLELESLRASYAEL--KAQSQEEIRRLWSQLESPRP 372
Cdd:pfam12128  410 LAVAEDDLQALESELREQLEAGKLE----FNEEEYRLKSRLGELKLRLNQATATPELLlqLENFDERIERAREEQEAANA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  373 DRQDAsartphgeeleQRERecgvqQQRRGRRAEQESELGQSPEGAAERgredpvllEQRLQDATEEPSLESGGIGPSSM 452
Cdd:pfam12128  486 EVERL-----------QSEL-----RQARKRRDQASEALRQASRRLEER--------QSALDELELQLFPQAGTLLHFLR 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  453 REGERREQRVGPSLQPELAenHRCHLTAwtssleaqqqaglVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDT 532
Cdd:pfam12128  542 KEAPDWEQSIGKVISPELL--HRTDLDP-------------EVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  533 EVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLEnrnlheklqhevclkedLERVKHSLvEDHREELKKANERLQLVKQE 612
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASRE-----------------ETFARTAL-KNARLDLRRLFDEKQSEKDK 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  613 LKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQsvinkfELREIKMRQLQDQQAaqildLEGSLVEQQGRLRQL 692
Cdd:pfam12128  669 KNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKE------QKREARTEKQAYWQV-----VEGALDAQLALLKAA 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  693 EHGLEAEECPRCGHCGQEPAGRVAPADQDWELATRRLREdcALQLMQAQSRFLKERKELTEKFTAEQDALLQEAQEKHAc 772
Cdd:pfam12128  738 IAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKRE--IRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLAT- 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  773 dmrlLQERHQQHVLSLTAQLeARRRAEVEELKASVESERWAL--AEARVAELQTEHAAAISALEARHSALLGSLESRHLS 850
Cdd:pfam12128  815 ----QLSNIERAISELQQQL-ARLIADTKLRRAKLEMERKASekQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIG 889

                          730       740
                   ....*....|....*....|....*
gi 1953366519  851 EVQAMREEHRQALEQLRVDLEKQLQ 875
Cdd:pfam12128  890 ERLAQLEDLKLKRDYLSESVKKYVE 914
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2464-2903 4.81e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 4.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2464 LEKVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRM------THLQNQEKLQQLCAALTSAEARGSRQEHQLRR-QVELL 2536
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEaeekeeEYAELQEELEELEEELEELEAELEELREELEKlEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2537 AYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEvlQLRSVLDSKESn 2616
Cdd:COG4717    127 LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEE--ELQDLAEELEE- 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2617 LRAALQELESERGKERALQSRLEEaQLQHLQREGQSSKTLEELRASLEKQFAQSSqLCVALKHEQTAKDNLQKELQIEAS 2696
Cdd:COG4717    204 LQQRLAELEEELEEAQEELEELEE-ELEQLENELEAAALEERLKEARLLLLIAAA-LLALLGLGGSLLSLILTIAGVLFL 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2697 RCEALLA----QERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQ---LSRGPRESPAHHALLRKLKEEKSRAAELQA 2769
Cdd:COG4717    282 VLGLLALlfllLAREKASLGKEAEELQALPALEELEEEELEELLAALglpPDLSPEELLELLDRIEELQELLREAEELEE 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2770 RLEQVQRQQEADVQKRRAELEREKEVRAAqarepgrcLRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAE 2849
Cdd:COG4717    362 ELQLEELEQEIAALLAEAGVEDEEELRAA--------LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE 433

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1953366519 2850 MRptGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERL 2903
Cdd:COG4717    434 LE--ELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAEL 485
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 2506-2789 4.99e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 49.28  E-value: 4.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2506 EKLQQLCAALTS-AEARGSRQEHQLRRQVellaykVEQEKRIASDVQKTLTEEQEKASSVRKLLVV---EQTVVrdlrse 2581
Cdd:PRK10929    45 EIVEALQSALNWlEERKGSLERAKQYQQV------IDNFPKLSAELRQQLNNERDEPRSVPPNMSTdalEQEIL------ 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2582 lreckQDNERLLASLGEAQKEVLQLRSVLDS------KESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSK- 2654
Cdd:PRK10929   113 -----QVSSQLLEKSRQAQQEQDRAREISDSlsqlpqQQTEARRQLNEIERRLQTLGTPNTPLAQAQLTALQAESAALKa 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2655 TLEELraslekQFAQSSqlcvALKHEQTAKdnLQKEL-QIEASRCEALLAQERGQLSElQRSLEAEKgrslelaaALRHE 2733
Cdd:PRK10929   188 LVDEL------ELAQLS----ANNRQELAR--LRSELaKKRSQQLDAYLQALRNQLNS-QRQREAER--------ALEST 246

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1953366519 2734 RLLTEQLSRGPRespahhALLRKLK--EEKSRAAELQA-RLEQV---QRQQEADVQKRRAEL 2789
Cdd:PRK10929   247 ELLAEQSGDLPK------SIVAQFKinRELSQALNQQAqRMDLIasqQRQAASQTLQVRQAL 302
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 1353-1604 5.04e-05

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 49.08  E-value: 5.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1353 DSALRREVECLTQEQSEARKQsekdraalLSQMKVFEAELEEQLsrHEAC-AKQAEelsalRQQMAALDKHLRSQRQfmD 1431
Cdd:pfam09726  418 EQELRSQISSLTSLERSLKSE--------LGQLRQENDLLQTKL--HNAVsAKQKD-----KQTVQQLEKRLKAEQE--A 480

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1432 EQAVEREHEREefqREIQRLEEQLRQAARPRPHGPRVSDVELLQEKLREKsdgfnELVIKKelADRQVMIQEEEIRRLEE 1511
Cdd:pfam09726  481 RASAEKQLAEE---KKRKKEEEATAARAVALAAASRGECTESLKQRKREL-----ESEIKK--LTHDIKLKEEQIRELEI 550

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1512 tnascrrEAAQLREELERQRDA---MKALQ--QDKEALQEKQMSnlllvSTLQSKLDegrcpvppADSCPEGPEVQLEAV 1586
Cdd:pfam09726  551 -------KVQELRKYKESEKDTevlMSALSamQDKNQHLENSLS-----AETRIKLD--------LFSALGDAKRQLEIA 610

                          250
                   ....*....|....*...
gi 1953366519 1587 QRALQQRESEVLDLKEQL 1604
Cdd:pfam09726  611 QGQIYQKDQEIKDLKQKI 628
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 88-382 5.27e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.97  E-value: 5.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519   88 QDREQDCKLEIAQPMGRQEDEAGAQQQVAVELRQPAGMQQVQLQTQPVPSLELEALRLSLSNMHTAQLELTQANLQKEKE 167
Cdd:pfam17380  298 QERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRM 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  168 TALTELRamlngrhaQELALLRSRQQQELELAREQHAREQEEMR-----------LRCSQETAKLKEKLQSEMERnARAV 236
Cdd:pfam17380  378 RELERLQ--------MERQQKNERVRQELEAARKVKILEEERQRkiqqqkvemeqIRAEQEEARQREVRRLEEER-AREM 448

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  237 ESLKRDwESERGLCLENLRRELSAKHRSELENLQDQFKRELSEQ------KAELEKIFQAKNQAECALRTLEAQHEEALR 310
Cdd:pfam17380  449 ERVRLE-EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEqrrkilEKELEERKQAMIEEERKRKLLEKEMEERQK 527

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366519  311 QLREDLQSERCQyvqdlELRLRDQEVE--KQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDASARTP 382
Cdd:pfam17380  528 AIYEEERRREAE-----EERRKQQEMEerRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEATTP 596
PTZ00121 PTZ00121
MAEBL; Provisional
 1214-1512 5.54e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.37  E-value: 5.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1214 DSTRQLEEARQIHSRFEKEFSCKNEET--AQVVRKQQQLlERLEEENAARTRLMLELHQAQgiiEGFKEEKASLQEALCR 1291
Cdd:PTZ00121  1525 DEAKKAEEAKKADEAKKAEEKKKADELkkAEELKKAEEK-KKAEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKL 1600

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1292 QETAEHGLAEELEglrqQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQ---- 1367
Cdd:PTZ00121  1601 YEEEKKMKAEEAK----KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkk 1676

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1368 -SEARKQSEKDRAAllsqmkvfeaelEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQfmdeqavEREHEREEFQR 1446
Cdd:PTZ00121  1677 aEEAKKAEEDEKKA------------AEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEE-------ENKIKAEEAKK 1737

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1953366519 1447 EIQRLEEQLRQAARPRPHGPRVSDVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEET 1512
Cdd:PTZ00121  1738 EAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDI 1803
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1351-1557 8.61e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.58  E-value: 8.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1351 HEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEE-QLSRHEACAKQAEELSALRQQMAALDKHLRSQRQF 1429
Cdd:pfam17380  339 QERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERlQMERQQKNERVRQELEAARKVKILEEERQRKIQQQ 418

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1430 MDEQAVEREHEREEFQREIQRLEEQ-LRQAARPR-PHGPRVSDVELL----------------QEKLREKSDGFNELVIK 1491
Cdd:pfam17380  419 KVEMEQIRAEQEEARQREVRRLEEErAREMERVRlEEQERQQQVERLrqqeeerkrkklelekEKRDRKRAEEQRRKILE 498

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953366519 1492 KEL-ADRQVMIQEEEIRRLEETNASCRREAAQlreELERQRDAMKALQQDKEALQEKQMSNLLLVST 1557
Cdd:pfam17380  499 KELeERKQAMIEEERKRKLLEKEMEERQKAIY---EEERRREAEEERRKQQEMEERRRIQEQMRKAT 562
mukB PRK04863
chromosome partition protein MukB;
2598-2900 1.26e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.03  E-value: 1.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2598 EAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQ---------LQHLQREGQSSKTLEELRASLEKQfa 2668
Cdd:PRK04863   290 ELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASdhlnlvqtaLRQQEKIERYQADLEELEERLEEQ-- 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2669 qssQLCVALKHEQtakdnlQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRH-ERllTEQLSRGPRES 2747
Cdd:PRK04863   368 ---NEVVEEADEQ------QEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQAlER--AKQLCGLPDLT 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2748 PA-----HHALLRKLKE--EKSRAAELQARLEQVQRQQEADVQK--RRAELEREKEVRAAQAREPGRCLRREGHASQQqa 2818
Cdd:PRK04863   437 ADnaedwLEEFQAKEQEatEELLSLEQKLSVAQAAHSQFEQAYQlvRKIAGEVSRSEAWDVARELLRRLREQRHLAEQ-- 514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2819 gLEPLQAGLAAQEGR----KDARR----------------ADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQR 2878
Cdd:PRK04863   515 -LQQLRMRLSELEQRlrqqQRAERllaefckrlgknlddeDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQA 593

                          330       340
                   ....*....|....*....|....
gi 1953366519 2879 TVQALEAKEEA--AQRPEAERLQE 2900
Cdd:PRK04863   594 RIQRLAARAPAwlAAQDALARLRE 617
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2619-2851 1.30e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2619 AALQELESERGKERALQSRLEEAQlQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRC 2698
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELE-KELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2699 EALLAQERGQLSELQRSLEAEKGRSL--------ELAAALRHERLLTEQlsrgpreSPAHHALLRKLKEEKSRAAELQAR 2770
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPlalllspeDFLDAVRRLQYLKYL-------APARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2771 LEQVQRQQE---ADVQKRRAELEREKEVRAAQAREPGRCLRREGHA----SQQQAGLEPLQAGLAAQEGRKDARRADVGP 2843
Cdd:COG4942    169 LEAERAELEallAELEEERAALEALKAERQKLLARLEKELAELAAElaelQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ....*...
gi 1953366519 2844 GRADAEMR 2851
Cdd:COG4942    249 AALKGKLP 256
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1636-1721 1.33e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.93  E-value: 1.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1636 VRELQEENASLKAFLQNKEKEImcvsEQLEAQLAGMGSGALREVTYDRS-----SEIEELRSIIENLRENQQRLqKEKAE 1710
Cdd:COG2433    422 VERLEAEVEELEAELEEKDERI----ERLERELSEARSEERREIRKDREisrldREIERLERELEEERERIEEL-KRKLE 496

                           90
                   ....*....|.
gi 1953366519 1711 EMEQLHEVIER 1721
Cdd:COG2433    497 RLKELWKLEHS 507
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1438-1851 1.51e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 1.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1438 EHEREEFQREIQRLEEQLRQAARPRphgprvSDVELLQEKLREKSDGFNELvikkeladrqvmiqEEEIRRLEETNASCR 1517
Cdd:PRK02224   212 ESELAELDEEIERYEEQREQARETR------DEADEVLEEHEERREELETL--------------EAEIEDLRETIAETE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1518 REAAQLREELERQRDAmkalqqdkealqekqmsnlllVSTLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRALQQRESEV 1597
Cdd:PRK02224   272 REREELAEEVRDLRER---------------------LEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRL 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1598 LDLKEQLGKMKDDLVSKSDEVLHLNleldaqsSRAAvsvrELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSgaLR 1677
Cdd:PRK02224   331 EECRVAAQAHNEEAESLREDADDLE-------ERAE----ELREEAAELESELEEAREAVEDRREEIEELEEEIEE--LR 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1678 EVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEelslgAPAVPAAVDCelpavpapavgPEALAAA 1757
Cdd:PRK02224   398 ERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-----AEALLEAGKC-----------PECGQPV 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1758 GAASRLFAEQEHRhgQALEALQQRLQAAEEAAAGQLAELERSAALREAE--VQAMASQIQAFEAALRAKEARLAERDLEI 1835
Cdd:PRK02224   462 EGSPHVETIEEDR--ERVEELEAELEDLEEEVEEVEERLERAEDLVEAEdrIERLEERREDLEELIAERRETIEEKRERA 539

                          410
                   ....*....|....*.
gi 1953366519 1836 DAMKRQKLAHSAELET 1851
Cdd:PRK02224   540 EELRERAAELEAEAEE 555
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 581-879 1.71e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.74  E-value: 1.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  581 KEDLERVkhslvEDHREELKKANERLQL----------VKQELKDKE-----AEWKVASEDLKR--KAEEELTLMLHDLK 643
Cdd:TIGR02168  185 RENLDRL-----EDILNELERQLKSLERqaekaerykeLKAELRELElallvLRLEELREELEElqEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  644 EQ-AEAEKQSVINKFELREIKMRQLQDQQ-----AAQILDLEGSLVEQQGRLRQLEHGLEAEECPRCGHcgQEPAGRVAP 717
Cdd:TIGR02168  260 AElQELEEKLEELRLEVSELEEEIEELQKelyalANEISRLEQQKQILRERLANLERQLEELEAQLEEL--ESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  718 ADQDWELATRRLREDCALQLmQAQSRFLKERKELTEKFTAEQDALLQEAQEKHacDMRLLQERHQQHVLSLTAQLEaRRR 797
Cdd:TIGR02168  338 ELAELEEKLEELKEELESLE-AELEELEAELEELESRLEELEEQLETLRSKVA--QLELQIASLNNEIERLEARLE-RLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  798 AEVEELKASVESERWALAEARVAELQT---EHAAAISALEARHSALlgsleSRHLSEVQAMREEHRQALEQLRVDLEKQL 874
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAeleELEEELEELQEELERL-----EEALEELREELEEAEQALDAAERELAQLQ 488


                   ....*
gi 1953366519  875 QEKEA 879
Cdd:TIGR02168  489 ARLDS 493
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2473-2902 1.79e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.53  E-value: 1.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2473 KSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRR-----------QVELLAYKVE 2541
Cdd:pfam12128  268 KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEAledqhgafldaDIETAAADQE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2542 QEKRIASDVQ------KTLTEEQ---EKASSVRKLLVVEQ--TVVRDLRSELRECKQDNERLLASL-GEAQKEVLQLRSV 2609
Cdd:pfam12128  348 QLPSWQSELEnleerlKALTGKHqdvTAKYNRRRSKIKEQnnRDIAGIKDKLAKIREARDRQLAVAeDDLQALESELREQ 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2610 LDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREgQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQK 2689
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLE-NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASE 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2690 ELQieasRCEALLAQERGQLSELQRSLEAEKGRSLELaaaLRHERLLTEQlSRGPRESPA--HHALLRKLKEEKSRAAEL 2767
Cdd:pfam12128  507 ALR----QASRRLEERQSALDELELQLFPQAGTLLHF---LRKEAPDWEQ-SIGKVISPEllHRTDLDPEVWDGSVGGEL 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2768 -----QARLEQVQRQQEADvqkrraeLEREKEVRAAQAREPgrclRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVG 2842
Cdd:pfam12128  579 nlygvKLDLKRIDVPEWAA-------SEEELRERLDKAEEA----LQSAREKQAAAEEQLVQANGELEKASREETFARTA 647

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2843 PGRADAEMRPTGAKEKLRELELQRQRDEHKiRQLQRTVQALEAKEEAAQRPEAERLQEER 2902
Cdd:pfam12128  648 LKNARLDLRRLFDEKQSEKDKKNKALAERK-DSANERLNSLEAQLKQLDKKHQAWLEEQK 706
PRK11281 PRK11281
mechanosensitive channel MscK;
2467-2741 1.84e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2467 VVQEQEKSLEHLRASDRSSllSEIQALRAQL-----RMThlQNQEKLQQLCAALTSA-------------EAR-GSRQEH 2527
Cdd:PRK11281    61 VQQDLEQTLALLDKIDRQK--EETEQLKQQLaqapaKLR--QAQAELEALKDDNDEEtretlstlslrqlESRlAQTLDQ 136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2528 QLRRQVELLAYKVE------QEKRiasdVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQK 2601
Cdd:PRK11281   137 LQNAQNDLAEYNSQlvslqtQPER----AQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQR 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2602 EVLQLRSVLdskesnlraalQELESERGKERALQSRLEEAQLQHLQ------REGQSSKTLEELRASLEKQFAQSSQLcv 2675
Cdd:PRK11281   213 KSLEGNTQL-----------QDLLQKQRDYLTARIQRLEHQLQLLQeainskRLTLSEKTVQEAQSQDEAARIQANPL-- 279

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953366519 2676 alkheqtakdnLQKELQIEASRCEALLAQERgQLSEL-QRSLEAEKgrslELAAALRHERLLTEQLS 2741
Cdd:PRK11281   280 -----------VAQELEINLQLSQRLLKATE-KLNTLtQQNLRVKN----WLDRLTQSERNIKEQIS 330
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
164-314 2.04e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 2.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  164 KEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRlRCSQETAKLKEKL----QSEMERNARAVESL 239
Cdd:COG4913    265 AAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELE-RLEARLDALREELdeleAQIRGNGGDRLEQL 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  240 KRD---WESERGLCLENLRR--------ELSAKH-RSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEE 307
Cdd:COG4913    344 EREierLERELEERERRRARleallaalGLPLPAsAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRE 423


                   ....*..
gi 1953366519  308 ALRQLRE 314
Cdd:COG4913    424 LEAEIAS 430
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2530-2789 2.14e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 2.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2530 RRQVELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVR------DLRSELRECkQDNERLLASLGEAQKEV 2603
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeiDVASAEREI-AELEAELERLDASSDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2604 LQLRSVLDSKESNLRAALQELESERGKERALQSRLEEA--QLQHLQR--EGQSSKTLEELRASLEKQFAQSSQlcvaLKH 2679
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAeeELDELQDrlEAAEDLARLELRALLEERFAAALG----DAV 763

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2680 EQTAKDNLQKE---LQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALR--HERLLTEQLsrgpresPAHHALL 2754
Cdd:COG4913    764 ERELRENLEERidaLRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLalLDRLEEDGL-------PEYEERF 836

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1953366519 2755 RKLKEEKSRA--AELQARLeqvqRQQEADVQKRRAEL 2789
Cdd:COG4913    837 KELLNENSIEfvADLLSKL----RRAIREIKERIDPL 869
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 169-439 2.56e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 2.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  169 ALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAvESLKRDWESERG 248
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI-EQLEQEEEKLKE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  249 LcLENLRRELSAKHRsELENLqdqfKRELSEQKAELEKIFQAKNQAECALRTLEAQ-HEEALRQLREDLQSERcQYVQDL 327
Cdd:TIGR02169  738 R-LEELEEDLSSLEQ-EIENV----KSELKELEARIEELEEDLHKLEEALNDLEARlSHSRIPEIQAELSKLE-EEVSRI 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  328 ELRLrdQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS----------ARTPHGEELEQRERECGVQ 397
Cdd:TIGR02169  811 EARL--REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLngkkeeleeeLEELEAALRDLESRLGDLK 888

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1953366519  398 QQRRGRRA---EQESELGQSpEGAAERGREDPVLLEQRLQDATEE 439
Cdd:TIGR02169  889 KERDELEAqlrELERKIEEL-EAQIEKKRKRLSELKAKLEALEEE 932
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 2589-2901 2.72e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 2.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2589 NER--LLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQ---------LQHLQREGQSSKTLE 2657
Cdd:COG3096    278 NERreLSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASdhlnlvqtaLRQQEKIERYQEDLE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2658 ELRASLEKQfaqssQLCVALKHEQtakdnlQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRH-ERll 2736
Cdd:COG3096    358 ELTERLEEQ-----EEVVEEAAEQ------LAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQAlEK-- 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2737 TEQLSRGPRESPA-----HHALLRKLKE--EKSRAAELQARLEQVQRQQ-----------------EADVQKRRAELERE 2792
Cdd:COG3096    425 ARALCGLPDLTPEnaedyLAAFRAKEQQatEEVLELEQKLSVADAARRQfekayelvckiageverSQAWQTARELLRRY 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2793 KEVRAAQAREPG--RCLRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELELQRQRDE 2870
Cdd:COG3096    505 RSQQALAQRLQQlrAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELR 584

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1953366519 2871 HKIRQLQRTVQALEAKEEA--AQRPEAERLQEE 2901
Cdd:COG3096    585 QQLEQLRARIKELAARAPAwlAAQDALERLREQ 617
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1355-1550 3.87e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 3.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1355 ALRREVECLTQEQSEARKQSEKDRAALlsqmkvfeAELEEQLSRHEACAKQ----------AEELSALRQQMAALD---- 1420
Cdd:COG4913    614 ALEAELAELEEELAEAEERLEALEAEL--------DALQERREALQRLAEYswdeidvasaEREIAELEAELERLDassd 685

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1421 --KHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAarprphgprvsdvELLQEKLREKSDGFNELVIKKELADRQ 1498
Cdd:COG4913    686 dlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA-------------EEELDELQDRLEAAEDLARLELRALLE 752

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1953366519 1499 VMIQEEEIRRLEetnascrreaAQLREELERQRDAMKALQQDKEALQEKQMS 1550
Cdd:COG4913    753 ERFAAALGDAVE----------RELRENLEERIDALRARLNRAEEELERAMR 794
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 2458-2800 3.97e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 46.25  E-value: 3.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2458 SSLLERLEKVVQEQEKSLEHLRA--SDRSSLLSEiqalRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVEL 2535
Cdd:pfam05483  390 SSELEEMTKFKNNKEVELEELKKilAEDEKLLDE----KKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTS 465

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2536 LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVR---DLRSELRE-------CKQDNERLLASLGEAQKEVLQ 2605
Cdd:pfam05483  466 EEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQeasDMTLELKKhqediinCKKQEERMLKQIENLEEKEMN 545

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2606 LRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLE---KQFAQSSQLCVALKHEQT 2682
Cdd:pfam05483  546 LRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEnknKNIEELHQENKALKKKGS 625

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2683 AKDNLQKELQIEASRCEALLAQERGQLSEL----QRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPahhallrklK 2758
Cdd:pfam05483  626 AENKQLNAYEIKVNKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEID---------K 696

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1953366519 2759 EEKSRAAELQARLEQVQRQQEADVQKRRAEL----EREKEVRAAQA 2800
Cdd:pfam05483  697 RCQHKIAEMVALMEKHKHQYDKIIEERDSELglykNKEQEQSSAKA 742
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 2454-2915 4.42e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.12  E-value: 4.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2454 PGEHSSLLERLEKVVQEQEKSLEHLRASdrSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQV 2533
Cdd:TIGR00618  162 SKEKKELLMNLFPLDQYTQLALMEFAKK--KSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQ 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2534 ELLAYKVEQEkriasdvqktltEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERL-----LASLGEAQKEVLQLRS 2608
Cdd:TIGR00618  240 QSHAYLTQKR------------EAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERInrarkAAPLAAHIKAVTQIEQ 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2609 VLDSKESNLRAALQELESERGKERALQSRLEEAQ-----LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTA 2683
Cdd:TIGR00618  308 QAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEeqrrlLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2684 KDNLQKELQIEASRCEALLAQERGQLSELQRS-------LEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRK 2756
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFrdlqgqlAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQS 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2757 LKEEKSRAAELQARLEQVQR--QQEADVQKRRAELEREKEvraaqarepGRCLRREGHAsQQQAGLEPLQAGLAAQEgrk 2834
Cdd:TIGR00618  468 LKEREQQLQTKEQIHLQETRkkAVVLARLLELQEEPCPLC---------GSCIHPNPAR-QDIDNPGPLTRRMQRGE--- 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2835 dARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEaERLQEERLGLERVRQQLLC 2914
Cdd:TIGR00618  535 -QTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNIT-VRLQDLTEKLSEAEDMLAC 612


                   .
gi 1953366519 2915 A 2915
Cdd:TIGR00618  613 E 613
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2511-2749 4.92e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2511 LCAALTSAEARGSRQEHQLRRQvellaykvEQEKRIASdVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNE 2590
Cdd:COG4942      9 LLLALAAAAQADAAAEAEAELE--------QLQQEIAE-LEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2591 RLLASLGEAQKEVLQLRSVLDSKESNLR---AALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQF 2667
Cdd:COG4942     80 ALEAELAELEKEIAELRAELEAQKEELAellRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADL 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2668 AQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRES 2747
Cdd:COG4942    160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239


                   ..
gi 1953366519 2748 PA 2749
Cdd:COG4942    240 AE 241
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 126-346 5.11e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 5.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  126 QQVQLQTQPVPSLELEALRLSLSNMHTAQleltQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELarEQHAR 205
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELES----KLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL--ESRLE 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  206 EQEEMRLRCSQETAKLKEKLQSEMERNARAVESLKRDWESerglcLENLRRELSAKHRSELENLQDQFKRELSEQKAELE 285
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDR-----RERLQQEIEELLKKLEEAELKELQAELEELEEELE 450

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953366519  286 KIFQAKNQAECALRTLE---AQHEEALRQLREDLQ--SERCQYVQDLELRLRD-QEVEKQLELESLR 346
Cdd:TIGR02168  451 ELQEELERLEEALEELReelEEAEQALDAAERELAqlQARLDSLERLQENLEGfSEGVKALLKNQSG 517
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2635-2999 5.25e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 5.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2635 QSRLEEAQlQHLQREGQsskTLEELRASLEKQFAQSSQlCVALKHEQTAKDNLQKELQIeasrceALLAQERGQLSELQR 2714
Cdd:TIGR02168  178 ERKLERTR-ENLDRLED---ILNELERQLKSLERQAEK-AERYKELKAELRELELALLV------LRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2715 SLEAEKGRSLELAAALRherLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQeadvQKRRAELEREKE 2794
Cdd:TIGR02168  247 ELKEAEEELEELTAELQ---ELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQIL----RERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2795 VRAAQAREPGR---CLRREGHASQQQagLEPLQAGLAAQEGRKDARRADvgpgRADAEMRPTGAKEKLRELELQRQRDEH 2871
Cdd:TIGR02168  320 ELEAQLEELESkldELAEELAELEEK--LEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2872 KIRQLQRTVQALEAKEEAAQRpEAERLQEERLGLERvrqQLLCAAGLLTSFISRTVDRTISDWTSSNEKAVTsLLHTLEE 2951
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLED-RRERLQQEIEELLK---KLEEAELKELQAELEELEEELEELQEELERLEE-ALEELRE 468

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2952 LKSELSTPSSSQKKMTAELQTQL--VDVLLKDNDSLTKALRTVTQEKAEL 2999
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQARLdsLERLQENLEGFSEGVKALLKNQSGL 518
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 154-875 5.47e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 5.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  154 QLELTQANLQKeKETALTELRAMLNGRHAQ-ELALlrsrQQQELELAREQHAREQEEMRLrcsQETAKLKEKLQSEMERN 232
Cdd:TIGR02168  180 KLERTRENLDR-LEDILNELERQLKSLERQaEKAE----RYKELKAELRELELALLVLRL---EELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  233 ARAVESLKRDwESERGLCLENLRRElsakhRSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQL 312
Cdd:TIGR02168  252 EEELEELTAE-LQELEEKLEELRLE-----VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  313 REDLQS-----ERCQYVQDLELRLRDQEVEKQLELESLRASYAELKAQSQE------------------------EIRRL 363
Cdd:TIGR02168  326 EELESKldelaEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEleeqletlrskvaqlelqiaslnnEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  364 WSQLES--PRPDRQDASARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEps 441
Cdd:TIGR02168  406 EARLERleDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE-- 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  442 LESGGIGPSSMREGERREQRVGPSLQPELAENHRCHLTA------------WTSSLEA----QQQAGLVETQESEGEQRE 505
Cdd:TIGR02168  484 LAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvdegYEAAIEAalggRLQAVVVENLNAAKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  506 GLSEGPGQELTQVPVPCAQGTALKVDTEVVARG----LGLEAEHRLKLLLLQTELKEEM------DVLKLENRNLHEKLQ 575
Cdd:TIGR02168  564 FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNiegfLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  576 HEVCLKEDLERV------------KHSLVEDHREELKKANERLQLVKQELKDKEAEWKVAsedlkRKAEEELTLMLHDLK 643
Cdd:TIGR02168  644 GYRIVTLDGDLVrpggvitggsakTNSSILERRREIEELEEKIEELEEKIAELEKALAEL-----RKELEELEEELEQLR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  644 EQAEAEKQSV------INKFELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEECPRcghcgQEPAGRVAP 717
Cdd:TIGR02168  719 KELEELSRQIsalrkdLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI-----EELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  718 ADQDWELATRRLRE-DCALQLMQAQSRFLKERKELTEKFTAEQDALLQEAQEKHAcDMRLLQERHQQHVLSLTAQLEARR 796
Cdd:TIGR02168  794 LKEELKALREALDElRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE-ELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366519  797 RaEVEELKASVESERWALAEARvaELQTEHAAAISALEARHSALLGSLEsrhlsEVQAMREEHRQALEQLRVDLEKQLQ 875
Cdd:TIGR02168  873 S-ELEALLNERASLEEALALLR--SELEELSEELRELESKRSELRRELE-----ELREKLAQLELRLEGLEVRIDNLQE 943
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2479-2710 5.70e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 5.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2479 RASDRSSLLSEIQALRAQLRmthlQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRIASDVQKTLTEEQ 2558
Cdd:COG4942     25 AEAELEQLQQEIAELEKELA----ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2559 EKASSVRKLLVVEQTVVRDLRSEL---RECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQ 2635
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1953366519 2636 SRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEAL-LAQERGQLS 2710
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAgFAALKGKLP 256
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1352-1744 5.73e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 45.66  E-value: 5.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1352 EDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQR---- 1427
Cdd:pfam07888   49 AQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRaahe 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1428 ----------QFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPrvSDVELLQEKLREKSDGFNELVIKKELADR 1497
Cdd:pfam07888  129 arireleediKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQ--AKLQQTEEELRSLSKEFQELRNSLAQRDT 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1498 QVMIQEEEIRRLEETNASCRREAAQ---LREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcpvppads 1574
Cdd:pfam07888  207 QVLQLQDTITTLTQKLTTAHRKEAEneaLLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQAR-------- 278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1575 cpegpevqLEAVQRALQQRESEvLDLKEQLGKMkddlvSKSDEVLHLNLELDAQSsraavsVRELQEENASLKAFLQNKE 1654
Cdd:pfam07888  279 --------LQAAQLTLQLADAS-LALREGRARW-----AQERETLQQSAEADKDR------IEKLSAELQRLEERLQEER 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1655 KEimcvSEQLEAQLAGMGSGALREVTyDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVP 1734
Cdd:pfam07888  339 ME----REKLEVELGREKDCNRVQLS-ESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETVADAKWSEAA 413

                          410
                   ....*....|
gi 1953366519 1735 AAVDCELPAV 1744
Cdd:pfam07888  414 LTSTERPDSP 423
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 2425-2897 5.77e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 45.94  E-value: 5.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2425 EFLQAVQEAFGKEREMlRAELQPRPcgsapGEHSSLLERLEKVVQEQEKSLEHLRaSDRSSLLSEIQALRAQLRmthlQN 2504
Cdd:pfam01576   47 EQLQAETELCAEAEEM-RARLAARK-----QELEEILHELESRLEEEEERSQQLQ-NEKKKMQQHIQDLEEQLD----EE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2505 QEKLQQLCAALTSAEARGSRQEHQL----RRQVELLAYKVEQEKRIaSDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRS 2580
Cdd:pfam01576  116 EAARQKLQLEKVTTEAKIKKLEEDIllleDQNSKLSKERKLLEERI-SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEE 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2581 ELRECKQDNERLLAS--------------LGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEE--AQLQ 2644
Cdd:pfam01576  195 RLKKEEKGRQELEKAkrklegestdlqeqIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIREleAQIS 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2645 HLQREGQSSKTleeLRASLEKQFAQSSQLCVALKHEqtakdnLQKELQIEASRCEaLLAQERGQLSELQRSLEAEKGRSL 2724
Cdd:pfam01576  275 ELQEDLESERA---ARNKAEKQRRDLGEELEALKTE------LEDTLDTTAAQQE-LRSKREQEVTELKKALEEETRSHE 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2725 ELAAALRHERL-----LTEQLSRGPRESPAHHALLRKLKEEKsraAELQARLEQVQrQQEADVQKRRAELEREKEVRAAQ 2799
Cdd:pfam01576  345 AQLQEMRQKHTqaleeLTEQLEQAKRNKANLEKAKQALESEN---AELQAELRTLQ-QAKQDSEHKRKKLEGQLQELQAR 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2800 AREPGRC-LRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVgpgrADAEMRPTGAKEKLRELELQRQRDEHKIRQLQR 2878
Cdd:pfam01576  421 LSESERQrAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDV----SSLESQLQDTQELLQEETRQKLNLSTRLRQLED 496

                          490       500
                   ....*....|....*....|.
gi 1953366519 2879 TVQALEAK--EEAAQRPEAER 2897
Cdd:pfam01576  497 ERNSLQEQleEEEEAKRNVER 517
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1356-1726 6.81e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 6.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1356 LRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEE--------LSALRQQMAALDKhLRSQR 1427
Cdd:PRK02224   182 LSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQAREtrdeadevLEEHEERREELET-LEAEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1428 QFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHgpRVSDVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIR 1507
Cdd:PRK02224   261 EDLRETIAETEREREELAEEVRDLRERLEELEEERDD--LLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQ 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1508 RLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKqmsnlllVSTLQSKLDEGRCPVPPADSCPEGPEVQLEAVQ 1587
Cdd:PRK02224   339 AHNEEAESLREDADDLEERAEELREEAAELESELEEAREA-------VEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1588 RALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDA----------QSSRAAVSVRELQEENASLKAFLQNKEKEI 1657
Cdd:PRK02224   412 DFLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEV 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1658 MCVSEQLEA--QLAGMGSG---------ALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEEL 1726
Cdd:PRK02224   492 EEVEERLERaeDLVEAEDRierleerreDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR 571
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
224-635 6.92e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 6.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  224 KLQSEMER--NAR-AVESLKRDWESErglcLENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRT 300
Cdd:PRK02224   163 KLEEYRERasDARlGVERVLSDQRGS----LDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  301 LE---AQHEEALRQLrEDLQSErcqyVQDLELRLRDQEVEKQL---ELESLRASYAELkaqsQEEIRRLWSQLESPRPDR 374
Cdd:PRK02224   239 ADevlEEHEERREEL-ETLEAE----IEDLRETIAETEREREElaeEVRDLRERLEEL----EEERDDLLAEAGLDDADA 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  375 QDASAR----TPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPS 450
Cdd:PRK02224   310 EAVEARreelEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEEL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  451 SMREGERREQRVGPSLQPELAENHRCHLTAWTSSL---EAQQQAGLVETQESEGEQREGLSEGP----GQELTQVPVPCa 523
Cdd:PRK02224   390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELrerEAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVE- 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  524 qgtALKVDTEVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRnlHEKLQHEVCLKEDLERVKHSLVEDHREELKKAN 603
Cdd:PRK02224   469 ---TIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR--IERLEERREDLEELIAERRETIEEKRERAEELR 543

                          410       420       430
                   ....*....|....*....|....*....|..
gi 1953366519  604 ERlqlvKQELKDKEAEWKVASEDLKRKAEEEL 635
Cdd:PRK02224   544 ER----AAELEAEAEEKREAAAEAEEEAEEAR 571
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 949-1725 6.98e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 45.73  E-value: 6.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  949 LAELRQETGKQQLHCQEEPEVLECPSEPfLEQQILQPKGEFESEKKVALHEKEIHGlECAQAQSLYQKEKESLFLQLQEK 1028
Cdd:pfam02463  221 LEEEYLLYLDYLKLNEERIDLLQELLRD-EQEEIESSKQEIEKEEEKLAQVLKENK-EEEKEKKLQEEELKLLAKEEEEL 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1029 NNQILQLKEQILSLSHEVEERRRDLEQLQQRRERENQEGTNLISMLKSdADLSDRERRALRDALRRLLSLFGEMLKVAIA 1108
Cdd:pfam02463  299 KSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKE-LEIKREAEEEEEEELEKLQEKLEQLEEELLA 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1109 LKSRISERVGLCLEDEDPPGAWPSGQALSAAPVLEETWPGSEAALLELDRSLPECVEMPSEAE-------ISSHICESFF 1181
Cdd:pfam02463  378 KKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIElkqgkltEEKEELEKQE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1182 MSPESSLEYEQPIRRIYQSLGLAVEGLLELALDSTRQLEEARQ----IHSRFEKEFSCKNEETAQVVRKQQQLLERLEE- 1256
Cdd:pfam02463  458 LKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQkeskARSGLKVLLALIKDGVGGRIISAHGRLGDLGVa 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1257 ----ENAARTRLMLELHQAQGIIEGFKEEKASL--------------QEALCRQETAEHGLAEELEGLRQQLQQAAQQQA 1318
Cdd:pfam02463  538 venyKVAISTAVIVEVSATADEVEERQKLVRALtelplgarklrlliPKLKLPLKSIAVLEIDPILNLAQLDKATLEADE 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1319 ELKEENSALWSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQlSR 1398
Cdd:pfam02463  618 DDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEI-LR 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1399 HEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRqaarprphgPRVSDVELLQEKL 1478
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEK---------SRLKKEEKEEEKS 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1479 REKSDgfNELVIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTL 1558
Cdd:pfam02463  768 ELSLK--EKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1559 QSKLDEGrcpvppadscpEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRE 1638
Cdd:pfam02463  846 QKLEKLA-----------EEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEE 914

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1639 LQEENASLKAFLQNKE--KEIMCVSEQLEAQLAGMGSGALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLH 1716
Cdd:pfam02463  915 KENEIEERIKEEAEILlkYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDE 994


                   ....*....
gi 1953366519 1717 EVIERLQEE 1725
Cdd:pfam02463  995 LEKERLEEE 1003
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2452-2903 7.41e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.49  E-value: 7.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2452 SAPGEHSSLLERLEkVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSA-----EARGSRQE 2526
Cdd:pfam15921  289 SARSQANSIQSQLE-IIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLAnseltEARTERDQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2527 H-----QLRRQVE-LLA--YKVEQEKRIASDVQKTLTEEQEKAS----SVRKLLVVEQTVVRDLRSELR----ECKQDNE 2590
Cdd:pfam15921  368 FsqesgNLDDQLQkLLAdlHKREKELSLEKEQNKRLWDRDTGNSitidHLRRELDDRNMEVQRLEALLKamksECQGQME 447

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2591 RLLASL---GEAQKEVLQLRSVLDSKESNLRAALQEL--------ESERG----------KERA----------LQSR-- 2637
Cdd:pfam15921  448 RQMAAIqgkNESLEKVSSLTAQLESTKEMLRKVVEELtakkmtleSSERTvsdltaslqeKERAieatnaeitkLRSRvd 527

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2638 LEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKE-------LQIEASRCEALLAQERGQLS 2710
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQLEKEINDRRLELQ 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2711 ELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRE--------SPAHHALLRKLKEEKSRAAELQARLEQVQR------ 2776
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSErlravkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRnfrnks 687

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2777 -QQEADVQKRRAELeREKEVRAAQAREPGRCLR-REGHASQQQAGlepLQAGLAAQEGRKDARRADVgpgRADAEMRPTG 2854
Cdd:pfam15921  688 eEMETTTNKLKMQL-KSAQSELEQTRNTLKSMEgSDGHAMKVAMG---MQKQITAKRGQIDALQSKI---QFLEEAMTNA 760

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1953366519 2855 AKEK--LRElelqrqrDEHKIRQLQRTVQAleAKEEAAQRPEAERLQEERL 2903
Cdd:pfam15921  761 NKEKhfLKE-------EKNKLSQELSTVAT--EKNKMAGELEVLRSQERRL 802
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2464-2738 8.27e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 8.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2464 LEKVVQEQEKSLEHLRasdrsSLLSEIQALRAQLRMTHLQNQEKLQQLcaaltsaeaRGSRQEHQ-LRRQVELLAYKVEQ 2542
Cdd:TIGR04523  372 IEKLKKENQSYKQEIK-----NLESQINDLESKIQNQEKLNQQKDEQI---------KKLQQEKElLEKEIERLKETIIK 437

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2543 EKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQ 2622
Cdd:TIGR04523  438 NNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTK 517

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2623 ELESERGKERALQSRLEEAQLQHLQREGQSSKTLEEL-RASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEAL 2701
Cdd:TIGR04523  518 KISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELkKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKE 597

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1953366519 2702 LAQERGQLSELQRSLEaEKGRSLELAAAlRHERLLTE 2738
Cdd:TIGR04523  598 KKDLIKEIEEKEKKIS-SLEKELEKAKK-ENEKLSSI 632
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2456-2900 8.55e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 8.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2456 EHSSLLERLEKVVQEQEKSLEHLRA--SDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQV 2533
Cdd:PRK02224   245 EHEERREELETLEAEIEDLRETIAEteREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2534 ELLAYKVEQEKRI-------------ASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQ 2600
Cdd:PRK02224   325 ELRDRLEECRVAAqahneeaeslredADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAP 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2601 KEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAqlQHLQREG----------------------QSSKTLEE 2658
Cdd:PRK02224   405 VDLGNAEDFLEELREERDELREREAELEATLRTARERVEEA--EALLEAGkcpecgqpvegsphvetieedrERVEELEA 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2659 LRASLEKQFAQSSQLCVALKHEQTAKDNLQKeLQIEASRCEALLAQERGQLSELQRSLEAEKGRSLEL-AAALRHERLLT 2737
Cdd:PRK02224   483 ELEDLEEEVEEVEERLERAEDLVEAEDRIER-LEERREDLEELIAERRETIEEKRERAEELRERAAELeAEAEEKREAAA 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2738 EQLSRGPRESPAHHALLRKLKEEKSR------AAELQARLEQVQRQQEADVQKR--RAELEREKEVRAAQAREPGRCLR- 2808
Cdd:PRK02224   562 EAEEEAEEAREEVAELNSKLAELKERieslerIRTLLAAIADAEDEIERLREKReaLAELNDERRERLAEKRERKRELEa 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2809 --REGHASQQQAGLEPLQAGLAAQEGRKDARRADvgpgRADAEMRPTGAKEKLRELElqRQRDEHKirQLQRTVQALEAK 2886
Cdd:PRK02224   642 efDEARIEEAREDKERAEEYLEQVEEKLDELREE----RDDLQAEIGAVENELEELE--ELRERRE--ALENRVEALEAL 713

                          490
                   ....*....|....
gi 1953366519 2887 EEaaqrpEAERLQE 2900
Cdd:PRK02224   714 YD-----EAEELES 722
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 184-877 9.20e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.34  E-value: 9.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  184 ELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAVESLKRDWESErglclENLRRELsakhr 263
Cdd:TIGR00618  180 QLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSH-----AYLTQKR----- 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  264 sELENLQDQFKRELSEQKAELEKifqaknqaecaLRTLEAQHEEALRQLREDLQSERCQYVQDLELRLRDQEVEKQLELE 343
Cdd:TIGR00618  250 -EAQEEQLKKQQLLKQLRARIEE-----------LRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  344 SLRASYAELKAQSQEeirrlwSQLESPRPDRQDASARTPHGEELEQReRECGVQQQRRGRRAEQESELgqSPEGAAERGR 423
Cdd:TIGR00618  318 SKMRSRAKLLMKRAA------HVKQQSSIEEQRRLLQTLHSQEIHIR-DAHEVATSIREISCQQHTLT--QHIHTLQQQK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  424 EDPVLLEQRLQDATEEPSLESGGIGPSSMREGERREQRVGPSLQPELAENHRCHLTAWTSSLEAQQQAGLVETQESEGEQ 503
Cdd:TIGR00618  389 TTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  504 REGLsegpgQELTQVPVPCAQGTALKvdTEVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLE--NRNLHEKLQHEVCLK 581
Cdd:TIGR00618  469 KERE-----QQLQTKEQIHLQETRKK--AVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGplTRRMQRGEQTYAQLE 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  582 EDLERVKHSLVEDhREELKKANERLQLVKQELKDKEAEWKVASEDLKrKAEEELTLMLHDLKEQAEAEKQsvinKFELRE 661
Cdd:TIGR00618  542 TSEEDVYHQLTSE-RKQRASLKEQMQEIQQSFSILTQCDNRSKEDIP-NLQNITVRLQDLTEKLSEAEDM----LACEQH 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  662 IKMRQLQDQQAAQILDLEGSLVEQqgRLRQLEHGLEAEEcprcghcgqepagrVAPADQDWELATRRLREDCALQLMQAQ 741
Cdd:TIGR00618  616 ALLRKLQPEQDLQDVRLHLQQCSQ--ELALKLTALHALQ--------------LTLTQERVREHALSIRVLPKELLASRQ 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  742 SRFLKERKELTE----KFTAEQDALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEVEELKASVESERWALAEA 817
Cdd:TIGR00618  680 LALQKMQSEKEQltywKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKAR 759

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  818 RVAELQTEHAAAIsalearhsALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEK 877
Cdd:TIGR00618  760 TEAHFNNNEEVTA--------ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQE 811
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 950-1600 9.62e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 9.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  950 AELRQETGKQQLHCQEEPEVLecpsepfLEQQILQPKGEFESEKKvALHEKEihglecAQAQSLYQKEKEsLFLQLQEKN 1029
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAE-------LEEKLEELKEELESLEA-ELEELE------AELEELESRLEE-LEEQLETLR 385

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1030 NQILQLKEQILSLSHEVEERRRDLEQLQQRRERENQEGTNLismLKSDADLSDRERRALRDALRRLLSLFGEMLKVAIAL 1109
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEEL---LKKLEEAELKELQAELEELEEELEELQEELERLEEA 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1110 KSRISERVGLCLEDEDPPG-------------------------------AWPSGQALSAAPVLE--ETWPGSEAALLEL 1156
Cdd:TIGR02168  463 LEELREELEEAEQALDAAErelaqlqarldslerlqenlegfsegvkallKNQSGLSGILGVLSEliSVDEGYEAAIEAA 542

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1157 DRSLPECVEMPSEAEISSHICesfFMSPESS-----LEYEQPIRRIYQSLGLAVEGLLELALDSTRQLEEARqihSRFEK 1231
Cdd:TIGR02168  543 LGGRLQAVVVENLNAAKKAIA---FLKQNELgrvtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFD---PKLRK 616

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1232 EFS--------CKNEETAQVVRKQQQLLERL------------------EEENAARTRLMLELHQAQGIIEGFKEEKASL 1285
Cdd:TIGR02168  617 ALSyllggvlvVDDLDNALELAKKLRPGYRIvtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAEL 696

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1286 QEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEAsaaeaeareagtpapIAHEDSALRREVECLTQ 1365
Cdd:TIGR02168  697 EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ---------------LEERIAQLSKELTELEA 761

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1366 EQSEARKQSEKDRAALLSQMKVFEaELEEQLSRH-EACAKQAEELSALRQQMAALDKHLRSQRQFMDE---QAVEREHER 1441
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIE-ELEAQIEQLkEELKALREALDELRAELTLLNEEAANLRERLESlerRIAATERRL 840

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1442 EEFQREIQRLEEQLRQAArprphgprvSDVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREAA 1521
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLA---------AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1522 QLREELERQRDAMKALQQDKEALQekqmsnlLLVSTLQSKL-DEGRCPVPPADSCPEGPEVQLEAVQRALQQRESEVLDL 1600
Cdd:TIGR02168  912 ELRRELEELREKLAQLELRLEGLE-------VRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
164-700 1.00e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  164 KEKETALTELRAMLNG--RHAQELALLRSR--QQQELELAREQHAREQEEmRLRCSQETAKLKEKLQSEMERNARAVESL 239
Cdd:PRK03918   210 NEISSELPELREELEKleKEVKELEELKEEieELEKELESLEGSKRKLEE-KIRELEERIEELKKEIEELEEKVKELKEL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  240 KrdWESERGLCLENLRRELS----------AKHRSELENLQDQFKrELSEQKAELEKIFQAKNQAECALRTLEAQHE--E 307
Cdd:PRK03918   289 K--EKAEEYIKLSEFYEEYLdelreiekrlSRLEEEINGIEERIK-ELEEKEERLEELKKKLKELEKRLEELEERHElyE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  308 ALRQLREDLQSercqyvqdLELRLRDQEVEK-QLELESLRASYAELKaQSQEEIRRLWSQLESPRPDRQDASartphgEE 386
Cdd:PRK03918   366 EAKAKKEELER--------LKKRLTGLTPEKlEKELEELEKAKEEIE-EEISKITARIGELKKEIKELKKAI------EE 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  387 LEQRERECGVQqqrrGRRAEQESELGQSPEGAAERGRedpvlLEQRLQDATEEpslesggigpssMREGERREQRVGPSL 466
Cdd:PRK03918   431 LKKAKGKCPVC----GRELTEEHRKELLEEYTAELKR-----IEKELKEIEEK------------ERKLRKELRELEKVL 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  467 --QPELAENHRchLTAWTSSLEAQQQAGLVETQESEGEQREGLSEgpgqeltqvpvpcaqgTALKVDTEVvaRGLGLEAE 544
Cdd:PRK03918   490 kkESELIKLKE--LAEQLKELEEKLKKYNLEELEKKAEEYEKLKE----------------KLIKLKGEI--KSLKKELE 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  545 HRLKLLLLQTELKEEMDVLKLENRNLHEKLQHE--VCLKEDLERVKhSLVEDHRE--ELKKANERLQLVKQELKDKEAEW 620
Cdd:PRK03918   550 KLEELKKKLAELEKKLDELEEELAELLKELEELgfESVEELEERLK-ELEPFYNEylELKDAEKELEREEKELKKLEEEL 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  621 KVASEDLKR--KAEEELTlmlhdlKEQAEAEKQSVINKFELREIKMRQLQDQQA---AQILDLEGSLVEQQGRLRQLEHG 695
Cdd:PRK03918   629 DKAFEELAEteKRLEELR------KELEELEKKYSEEEYEELREEYLELSRELAglrAELEELEKRREEIKKTLEKLKEE 702


                   ....*
gi 1953366519  696 LEAEE 700
Cdd:PRK03918   703 LEERE 707
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1637-1870 1.18e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1637 RELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGsgALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLH 1716
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIA--ALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1717 EVIERLQEELSLGAPAVPAAVDcelpavpapavGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAEL 1796
Cdd:COG4942    108 ELLRALYRLGRQPPLALLLSPE-----------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366519 1797 ERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAA 1870
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250
PTZ00121 PTZ00121
MAEBL; Provisional
 2432-2664 1.37e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.75  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2432 EAFGKEREMLRAELQPRpcgsAPGEHSSLLERLEKVVQEQEKSLEHLRASDRSSLLSEIQALR----AQLRMTHLQNQEK 2507
Cdd:PTZ00121  1555 EELKKAEEKKKAEEAKK----AEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKkaeeAKIKAEELKKAEE 1630

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2508 LQQLCAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRIASdvqktltEEQEKASSVRKLLVVEQTVVRDLRSELREcKQ 2587
Cdd:PTZ00121  1631 EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE-------EDKKKAEEAKKAEEDEKKAAEALKKEAEE-AK 1702

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2588 DNERLLASLGEAQKEVLQLRSvlDSKESNLRAALQELESERGKERALQSRLEEAQ---LQHLQREGQssKTLEELRASLE 2664
Cdd:PTZ00121  1703 KAEELKKKEAEEKKKAEELKK--AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEkkkIAHLKKEEE--KKAEEIRKEKE 1778
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1356-1725 1.39e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.65  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1356 LRREVECLTQEQSEARKQSEKDRAALLS-QMKVFEA----ELEEQLSRHEacakqaEELSALRQQMAALDKHLRSQRQFM 1430
Cdd:TIGR00606  596 LNKELASLEQNKNHINNELESKEEQLSSyEDKLFDVcgsqDEESDLERLK------EEIEKSSKQRAMLAGATAVYSQFI 669

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1431 DEQAVERE----------HEREEFQREIQRLEEQLRQAArprphgprvSDVELLQEKLREKSDGFNELVIKKELADRQVM 1500
Cdd:TIGR00606  670 TQLTDENQsccpvcqrvfQTEAELQEFISDLQSKLRLAP---------DKLKSTESELKKKEKRRDEMLGLAPGRQSIID 740

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1501 IQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQdKEALQEKQMSNLLLVSTLQSKLDEGRCPVPPADScpegpE 1580
Cdd:TIGR00606  741 LKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMP-EEESAKVCLTDVTIMERFQMELKDVERKIAQQAA-----K 814

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1581 VQLEAVQRALQQRESEVLDLKEQLgkmkDDLVSKSDEvlhlnleldaqssraavsVRELQEENASLKAFLQNKEKEIMcv 1660
Cdd:TIGR00606  815 LQGSDLDRTVQQVNQEKQEKQHEL----DTVVSKIEL------------------NRKLIQDQQEQIQHLKSKTNELK-- 870

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366519 1661 SEQLEAQLAGMGSGALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEE 1725
Cdd:TIGR00606  871 SEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETS 935
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 2570-2900 1.40e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.58  E-value: 1.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2570 VEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEE---AQLQHL 2646
Cdd:pfam02463  153 ERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEeylLYLDYL 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2647 QREGQSSKTLEELRASLEKQFAQSSQLCVAlkheQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKgRSLEL 2726
Cdd:pfam02463  233 KLNEERIDLLQELLRDEQEEIESSKQEIEK----EEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEL-LKLER 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2727 aaalrherllteqlsrgprespAHHALLRKLKEEKSRAAELQARLEQVQRQQEAdvqkRRAELEREKEVRAAQAREPGRC 2806
Cdd:pfam02463  308 ----------------------RKVDDEEKLKESEKEKKKAEKELKKEKEEIEE----LEKELKELEIKREAEEEEEEEL 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2807 LRREGHASQQQAGLEPLQAGLAAQEGRKDARRadvgpgradaemrptGAKEKLRELELQRQRDEHKIRQLQRTVQALEAK 2886
Cdd:pfam02463  362 EKLQEKLEQLEEELLAKKKLESERLSSAAKLK---------------EEELELKSEEEKEAQLLLELARQLEDLLKEEKK 426

                          330
                   ....*....|....
gi 1953366519 2887 EEAAQRPEAERLQE 2900
Cdd:pfam02463  427 EELEILEEEEESIE 440
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2690-2974 1.44e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2690 ELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRK----LKEEKSRAA 2765
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAeveqLEERIAQLS 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2766 ELQARLEQVQRQQEADVQKRRAELEREKEVRAAQARepgrclRREGHASQQQAGLEPLQAgLAAQEGRKDARRADVGPGR 2845
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEA------QIEQLKEELKALREALDE-LRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2846 ADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRpEAERLQEERLGLERVRQQLLCAAglltsfisR 2925
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELES-ELEALLNERASLEEALALLRSEL--------E 897

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1953366519 2926 TVDRTISDWtssnEKAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQL 2974
Cdd:TIGR02168  898 ELSEELREL----ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2813-3009 1.53e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2813 ASQQQAGLEPLQAGLAAQEGRKD---ARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEA 2889
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAalkKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2890 AQRPEAERLQE-ERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNEKAVTSLLHTLEELKSELSTPSSSQKKMTA 2968
Cdd:COG4942    102 QKEELAELLRAlYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1953366519 2969 ELQTQLVDvLLKDNDSLTKALRTVTQEKAELCRAVSQLEKS 3009
Cdd:COG4942    182 ELEEERAA-LEALKAERQKLLARLEKELAELAAELAELQQE 221
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 251-319 2.13e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.05  E-value: 2.13e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953366519  251 LENLRRELSAKHRsELENL---QDQFKRELSEQKAELEKIFQ-----AKNQAECALRTLEAQHEEALRQLREDLQSE 319
Cdd:PRK00409   525 LEELERELEQKAE-EAEALlkeAEKLKEELEEKKEKLQEEEDklleeAEKEAQQAIKEAKKEADEIIKELRQLQKGG 600
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2456-2794 2.23e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.77  E-value: 2.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2456 EHSSLLERLEKVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVEL 2535
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2536 -----------LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVL 2604
Cdd:COG1196    523 agavavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD 602

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2605 QLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAK 2684
Cdd:COG1196    603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2685 DNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRA 2764
Cdd:COG1196    683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1953366519 2765 AELQARLEQVQRQQEA-------------DVQKRRAELEREKE 2794
Cdd:COG1196    763 EELERELERLEREIEAlgpvnllaieeyeELEERYDFLSEQRE 805
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1252-1466 2.36e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1252 ERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQK 1331
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1332 EASAAEAEAR--------EAGTPAPIAHEDSALR-----REVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSR 1398
Cdd:COG4942    100 EAQKEELAELlralyrlgRQPPLALLLSPEDFLDavrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953366519 1399 HEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGP 1466
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1230-1727 2.42e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.90  E-value: 2.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1230 EKEFscknEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQ 1309
Cdd:PRK03918   199 EKEL----EEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKE 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1310 LQQAAQQQAELKEENsalwsqkeasaaeaeareagtpaPIAHEDSALRREVECLTQEQSEArkqsEKDRAALLSQMKVFE 1389
Cdd:PRK03918   275 IEELEEKVKELKELK-----------------------EKAEEYIKLSEFYEEYLDELREI----EKRLSRLEEEINGIE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1390 AELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRphgprvs 1469
Cdd:PRK03918   328 ERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAK------- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1470 dvELLQEKLREKSDGFNELviKKELADRQVMIqeEEIRRLEETNASCRREAAQLREE--LERQRDAMKALQQDKEALQEK 1547
Cdd:PRK03918   401 --EEIEEEISKITARIGEL--KKEIKELKKAI--EELKKAKGKCPVCGRELTEEHRKelLEEYTAELKRIEKELKEIEEK 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1548 QMSNLLLVSTLQSKLDEGRCPVP---PADSCPEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNle 1624
Cdd:PRK03918   475 ERKLRKELRELEKVLKKESELIKlkeLAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE-- 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1625 ldaqssraavsvrELQEENASLKAFLQNKEKEImcvsEQLEAQLAGMGSGALREVtydrSSEIEELRSIIE---NLRENQ 1701
Cdd:PRK03918   553 -------------ELKKKLAELEKKLDELEEEL----AELLKELEELGFESVEEL----EERLKELEPFYNeylELKDAE 611

                          490       500
                   ....*....|....*....|....*.
gi 1953366519 1702 QRLQKEKaEEMEQLHEVIERLQEELS 1727
Cdd:PRK03918   612 KELEREE-KELKKLEEELDKAFEELA 636
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1403-1728 2.52e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 43.66  E-value: 2.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1403 AKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDVELLQEKLREKS 1482
Cdd:pfam10174  174 KKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1483 DgfnELVIKKELADRQVMIQEEEIRRLEETNASC---RREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQ 1559
Cdd:pfam10174  254 D---EVQMLKTNGLLHTEDREEEIKQMEVYKSHSkfmKNKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLK 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1560 SKLD--EGRCPVPpadscpegpEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVsvr 1637
Cdd:pfam10174  331 ESLTakEQRAAIL---------QTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINV--- 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1638 eLQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSGALREVTYDRSseIEELRSIIENLRENQQRLQKEKAEEMEQLHE 1717
Cdd:pfam10174  399 -LQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEA--LSEKERIIERLKEQREREDRERLEELESLKK 475

                          330
                   ....*....|.
gi 1953366519 1718 VIERLQEELSL 1728
Cdd:pfam10174  476 ENKDLKEKVSA 486
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1248-1728 2.71e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.80  E-value: 2.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1248 QQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSAL 1327
Cdd:TIGR00618  180 QLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQ 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1328 WSQKEASAAEAEAREAGTPAPIAHEDSALRREVECLTQEQsEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAE 1407
Cdd:TIGR00618  260 QLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHI-KAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQS 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1408 ELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREE---------FQREIQRLEEQLRQAARprphgpRVSDVELLQEKL 1478
Cdd:TIGR00618  339 SIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQhtltqhihtLQQQKTTLTQKLQSLCK------ELDILQREQATI 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1479 REKSDGFNELVIKKELADRQVMIQEEEIRRLE---ETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLV 1555
Cdd:TIGR00618  413 DTRTSAFRDLQGQLAHAKKQQELQQRYAELCAaaiTCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVV 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1556 STLQSKLDEGRCPVPPADSCPEgPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVS 1635
Cdd:TIGR00618  493 LARLLELQEEPCPLCGSCIHPN-PARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQS 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1636 VRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAG--MGSGALREVTYDRSSEIEELRsIIENLRENQQRLQKEKAEEME 1713
Cdd:TIGR00618  572 FSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAedMLACEQHALLRKLQPEQDLQD-VRLHLQQCSQELALKLTALHA 650

                          490
                   ....*....|....*
gi 1953366519 1714 QLHEVIERLQEELSL 1728
Cdd:TIGR00618  651 LQLTLTQERVREHAL 665
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1682-1953 2.97e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 2.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1682 DRSSEIEELRSIIENLRENQQRLQKEKAE---EMEQLHEVIERLQEELSlgapavpaavdcelpavpapAVGPEALAAAG 1758
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAEleaELEELRLELEELELELE--------------------EAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1759 AASRLFAEQEHRHG--QALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEID 1836
Cdd:COG1196    296 ELARLEQDIARLEErrRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1837 AMKRQKLAHSAELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRLSRQLQVLNQRFLRCQKEADKQQARGARLR 1916
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1953366519 1917 pRGARGLQGPGPRAEEASRDEASQQDVDSRQVASATQ 1953
Cdd:COG1196    456 -EEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2586-2845 2.97e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2586 KQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEK 2665
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2666 QFAQSSQLCVALkheqtAKDNLQKELQIEASRCEALLAQERGQLseLQRSLEAEKGRSLELAAALRHERLLTEQLSrgpr 2745
Cdd:COG4942    102 QKEELAELLRAL-----YRLGRQPPLALLLSPEDFLDAVRRLQY--LKYLAPARREQAEELRADLAELAALRAELE---- 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2746 espahhALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREpgrclrreghASQQQAGLEPLQA 2825
Cdd:COG4942    171 ------AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE----------AEELEALIARLEA 234

                          250       260
                   ....*....|....*....|
gi 1953366519 2826 GLAAQEGRKDARRADVGPGR 2845
Cdd:COG4942    235 EAAAAAERTPAAGFAALKGK 254
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1209-1611 2.98e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.49  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1209 LELALDSTRQ-LEEARQIHSRFEKEFSCKNEETAQvvrkqqqLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQE 1287
Cdd:PRK02224   319 LEDRDEELRDrLEECRVAAQAHNEEAESLREDADD-------LEERAEELREEAAELESELEEAREAVEDRREEIEELEE 391

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1288 ALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEareagtpapiahEDSALRREVECLTQEQ 1367
Cdd:PRK02224   392 EIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVE------------EAEALLEAGKCPECGQ 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1368 -----------SEARKQSEKdRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVE 1436
Cdd:PRK02224   460 pvegsphvetiEEDRERVEE-LEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRER 538

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1437 REHEREEFQrEIQRLEEQLRQAARprphgprvsDVELLQEKLREKSDGFNELviKKELADRQvmiqeEEIRRLEETNAsc 1516
Cdd:PRK02224   539 AEELRERAA-ELEAEAEEKREAAA---------EAEEEAEEAREEVAELNSK--LAELKERI-----ESLERIRTLLA-- 599

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1517 rrEAAQLREELERQRDAMKALQ----QDKEALQEKQMSnlllVSTLQSKLDEGRcpVPPADSCPEGPEVQLEAVQRALQQ 1592
Cdd:PRK02224   600 --AIADAEDEIERLREKREALAelndERRERLAEKRER----KRELEAEFDEAR--IEEAREDKERAEEYLEQVEEKLDE 671

                          410
                   ....*....|....*....
gi 1953366519 1593 RESEVLDLKEQLGKMKDDL 1611
Cdd:PRK02224   672 LREERDDLQAEIGAVENEL 690
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1245-1539 3.02e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 3.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1245 RKQQQLLERLEEEN--AARTRLMLELHQAQGIIEGFKEEKASL-QEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELK 1321
Cdd:pfam17380  287 RQQQEKFEKMEQERlrQEKEEKAREVERRRKLEEAEKARQAEMdRQAAIYAEQERMAMERERELERIRQEERKRELERIR 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1322 EENSALWSQKEASAAEAEAREagtpapiahedsalRREVECLTQEQSEARKQS--EKDRaallsQMKVFEAELEEQLSRH 1399
Cdd:pfam17380  367 QEEIAMEISRMRELERLQMER--------------QQKNERVRQELEAARKVKilEEER-----QRKIQQQKVEMEQIRA 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1400 EACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDVELLQEKLR 1479
Cdd:pfam17380  428 EQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA 507

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1480 EKSDGFNELVIKKELADRQVMIQEEEIRRLEETNascRREAAQLREELERQRDAMKALQQ 1539
Cdd:pfam17380  508 MIEEERKRKLLEKEMEERQKAIYEEERRREAEEE---RRKQQEMEERRRIQEQMRKATEE 564
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2748-2907 3.32e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 3.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2748 PAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELERE-------KEVRAAQAREPGRCLRREGHASQQQAG- 2819
Cdd:COG4913    258 RELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAelarleaELERLEARLDALREELDELEAQIRGNGg 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2820 --LEPLQAGLAAQEGRKDARRADVGpgRADAEMRPTGAKEKLRELELQRQRDEHK---------IRQLQRTVQALEAKEE 2888
Cdd:COG4913    338 drLEQLEREIERLERELEERERRRA--RLEALLAALGLPLPASAEEFAALRAEAAallealeeeLEALEEALAEAEAALR 415

                          170
                   ....*....|....*....
gi 1953366519 2889 AAQRpEAERLQEERLGLER 2907
Cdd:COG4913    416 DLRR-ELRELEAEIASLER 433
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1345-1458 3.66e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 43.40  E-value: 3.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1345 TPAPIAHEDSALRREVECLTQeQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEA-CAKQAEELSALRQQMAALDKHL 1423
Cdd:PRK11448   136 PPEDPENLLHALQQEVLTLKQ-QLELQAREKAQSQALAEAQQQELVALEGLAAELEEkQQELEAQLEQLQEKAAETSQER 214

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1953366519 1424 RSQRQFMDEQAVEREHEREEFQREIqrLEEQLRQA 1458
Cdd:PRK11448   215 KQKRKEITDQAAKRLELSEEETRIL--IDQQLRKA 247
COG3903 COG3903
Predicted ATPase [General function prediction only];
2578-2919 3.84e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 43.08  E-value: 3.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2578 LRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLE 2657
Cdd:COG3903    557 LRGLLREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAA 636

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2658 ELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLT 2737
Cdd:COG3903    637 AAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAA 716

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2738 EQLSRGPRESPAHHALLRkLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQQQ 2817
Cdd:COG3903    717 AAAAAAAAAALLAAAAAA-ALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAA 795

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2818 AGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAER 2897
Cdd:COG3903    796 AAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAA 875

                          330       340
                   ....*....|....*....|..
gi 1953366519 2898 LQEERLGLERVRQQLLCAAGLL 2919
Cdd:COG3903    876 AAAAAAAALLAAAAAAAAAAAA 897
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
217-416 4.06e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 4.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  217 ETAKLKEKLQSEMERNARAVESLKRDwESERGLCLENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAEC 296
Cdd:COG4913    245 EDAREQIELLEPIRELAERYAAARER-LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALRE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  297 ALRTLEAQHEEALRQLREDLQSERCQYVQDLELRLRD-QEVEKQ-----LELESLRASYAELKAQSQEEIRRLWSQLESP 370
Cdd:COG4913    324 ELDELEAQIRGNGGDRLEQLEREIERLERELEERERRrARLEALlaalgLPLPASAEEFAALRAEAAALLEALEEELEAL 403

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1953366519  371 RPDRQDASAR-TPHGEELEQRERECGVQQQRRGR--------RAEQESELGQSPE 416
Cdd:COG4913    404 EEALAEAEAAlRDLRRELRELEAEIASLERRKSNiparllalRDALAEALGLDEA 458
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 146-879 4.13e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.18  E-value: 4.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  146 SLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQeLALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEK- 224
Cdd:pfam15921  209 SMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQ-LEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKa 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  225 ---------LQSEME---RNARAVESLKRDWESERGLCLENLRRELSAKHRS---ELENLQDQF---KRELSEQKAELEK 286
Cdd:pfam15921  288 ssarsqansIQSQLEiiqEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMyedKIEELEKQLvlaNSELTEARTERDQ 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  287 IFQAKNQAECALRTLEAQHEEALRQLreDLQSERCQYVQDLEL-------RLRDQEVEKQLELESLRASYAELKAQSQEE 359
Cdd:pfam15921  368 FSQESGNLDDQLQKLLADLHKREKEL--SLEKEQNKRLWDRDTgnsitidHLRRELDDRNMEVQRLEALLKAMKSECQGQ 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  360 IRRLWSQLESPRPDRQDASARTPHGEELEQREREcgVQQQRRGRRAEQESelgqspegaAERGREDpvlLEQRLQDatEE 439
Cdd:pfam15921  446 MERQMAAIQGKNESLEKVSSLTAQLESTKEMLRK--VVEELTAKKMTLES---------SERTVSD---LTASLQE--KE 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  440 PSLESGGIGPSSMRegerreQRVGPSLQP-ELAENHRCHLTAWTSSLEA--QQQAGLVETQESEGEQREGLSEGPGQELT 516
Cdd:pfam15921  510 RAIEATNAEITKLR------SRVDLKLQElQHLKNEGDHLRNVQTECEAlkLQMAEKDKVIEILRQQIENMTQLVGQHGR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  517 QVPVpcAQGTALKVDTEVVARGLGLEAEH--RLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERVKHSL--- 591
Cdd:pfam15921  584 TAGA--MQVEKAQLEKEINDRRLELQEFKilKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLlne 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  592 VEDHREELKKANERLQLVKQELKDKEAEWKVASEDLK---RKAEEELTLMLHDLKEQAEAEKQSVINKFELREikmrqlq 668
Cdd:pfam15921  662 VKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKmqlKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQK------- 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  669 dqqaaQILDLEGSLVEQQGRLRQLEHGLEAEECPRcgHCGQEPAGRVapADQDWELATRRLREDCALQLMQAQSRFLKER 748
Cdd:pfam15921  735 -----QITAKRGQIDALQSKIQFLEEAMTNANKEK--HFLKEEKNKL--SQELSTVATEKNKMAGELEVLRSQERRLKEK 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  749 keltekfTAEQDALLQEAQEKHACDMRLLQERHQQHVlsltaQLEARRRAEVEELKASVESERWALAearvAELQTEHAA 828
Cdd:pfam15921  806 -------VANMEVALDKASLQFAECQDIIQRQEQESV-----RLKLQHTLDVKELQGPGYTSNSSMK----PRLLQPASF 869

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1953366519  829 AISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEKEA 879
Cdd:pfam15921  870 TRTHSNVPSSQSTASFLSHHSRKTNALKEDPTRDLKQLLQELRSVINEEPT 920
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1205-1608 4.48e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 4.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1205 VEGLLELALDSTRQLEEARQIHSRFeKEFSCKNEETAQVVRKQQQLLERLEEENAaRTRLMLELHQAQGIIEGFKEEKA- 1283
Cdd:PRK03918   306 LDELREIEKRLSRLEEEINGIEERI-KELEEKEERLEELKKKLKELEKRLEELEE-RHELYEEAKAKKEELERLKKRLTg 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1284 ----SLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEA----SAAEAEAREAGTPAPIAHEDSA 1355
Cdd:PRK03918   384 ltpeKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcGRELTEEHRKELLEEYTAELKR 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1356 LRREVECLTQEQSEARKQSEKDRAALLSQMKVFE--------AELEEQLSRH--EACAKQAEELSALRQQMAALDKHLRS 1425
Cdd:PRK03918   464 IEKELKEIEEKERKLRKELRELEKVLKKESELIKlkelaeqlKELEEKLKKYnlEELEKKAEEYEKLKEKLIKLKGEIKS 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1426 QRQFMdEQAVEREHEREEFQREIQRLEEQLRQAARpRPHGPRVSDVELLQEKLREKSDGFNELVIKKElADRQVMIQEEE 1505
Cdd:PRK03918   544 LKKEL-EKLEELKKKLAELEKKLDELEEELAELLK-ELEELGFESVEELEERLKELEPFYNEYLELKD-AEKELEREEKE 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1506 IRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLvsTLQSKLdegrcpvppadscpEGPEVQLEA 1585
Cdd:PRK03918   621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYL--ELSREL--------------AGLRAELEE 684

                          410       420
                   ....*....|....*....|...
gi 1953366519 1586 VQRALQQRESEVLDLKEQLGKMK 1608
Cdd:PRK03918   685 LEKRREEIKKTLEKLKEELEERE 707
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 797-1458 4.93e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 4.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  797 RAEVEELKASVESERWALAEARVAELQTEHAAAISALEArhsallgslESRHLSEVQAMREEHRQALEQLRVDLEKQLQE 876
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEE---------LEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  877 KEAshptpltqalekhplsHGQELPPVEGGLRtqtssgqlegvkapvpPEVQGAQQegapvpAEVEAQRpaLLAELRQET 956
Cdd:COG1196    290 EYE----------------LLAELARLEQDIA----------------RLEERRRE------LEERLEE--LEEELAELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  957 GKQQLHCQEEPEVLEcpsepflEQQILQPKgefESEKKVALHEKEihglecaQAQSLYQKEKESLFLQLQEKNNQILQLK 1036
Cdd:COG1196    330 EELEELEEELEELEE-------ELEEAEEE---LEEAEAELAEAE-------EALLEAEAELAEAEEELEELAEELLEAL 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1037 EQILSLSHEVEERRRDLEQLQQRRERENQEGTNLISMLKSDADLSDRERRALRDALRRLLSLFGEMLKVAIALKSRISER 1116
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1117 VGLCLEDED----------------PPGAWPSGQALSAAPVLEETWPGSEAALLELDRSLPECVEMPSEAEISSHICESF 1180
Cdd:COG1196    473 ALLEAALAElleelaeaaarlllllEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1181 FMSPESSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAA 1260
Cdd:COG1196    553 VEDDEVAAAAIEYLKA----AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1261 RTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEA 1340
Cdd:COG1196    629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1341 reagtpapIAHEDSALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQ----- 1415
Cdd:COG1196    709 --------LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREiealg 780

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 1953366519 1416 ---MAALD--KHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQA 1458
Cdd:COG1196    781 pvnLLAIEeyEELEERYDFLSEQREDLEEARETLEEAIEEIDRETRER 828
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2459-3011 5.17e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.75  E-value: 5.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2459 SLLERLEKVVQEQEKSLEHLRA---SDRSSLLSEIQALRAQLRmthlQNQEKLQQLCAALTSAEARgsrqEHQLRRQVEL 2535
Cdd:TIGR02169  304 ASLERSIAEKERELEDAEERLAkleAEIDKLLAEIEELEREIE----EERKRRDKLTEEYAELKEE----LEDLRAELEE 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2536 LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLR-------- 2607
Cdd:TIGR02169  376 VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAleikkqew 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2608 ---------SVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALK 2678
Cdd:TIGR02169  456 kleqlaadlSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGE 535

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2679 HEQTA--------KDNLQKELQIEASRCEALLAQERG-----------QLSELQRSLEAEKG------------------ 2721
Cdd:TIGR02169  536 RYATAievaagnrLNNVVVEDDAVAKEAIELLKRRKAgratflplnkmRDERRDLSILSEDGvigfavdlvefdpkyepa 615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2722 -----------RSLELAAALRHE-RLLT---EQLSRGPRESPAHHALLRKL---KEEKSRAAELQARLEQVQRqQEADVQ 2783
Cdd:TIGR02169  616 fkyvfgdtlvvEDIEAARRLMGKyRMVTlegELFEKSGAMTGGSRAPRGGIlfsRSEPAELQRLRERLEGLKR-ELSSLQ 694

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2784 KRRAELEREKEVRAAQAREPGRCLRR--------EGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRAD-AEMRPTG 2854
Cdd:TIGR02169  695 SELRRIENRLDELSQELSDASRKIGEiekeieqlEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARiEELEEDL 774

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2855 AKEKLRELELQRQRDEHKIRQLQRTVQALEAK----EEAAQRPEAE--RLQEERLGLERVRQQLLCAAGLLTSFIsrtvd 2928
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSRIPEIQAELSKLEEEvsriEARLREIEQKlnRLTLEKEYLEKEIQELQEQRIDLKEQI----- 849

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2929 rtisdwtSSNEKAVTSLLHTLEELKSELstpsSSQKKMTAELQTQLVDvLLKDNDSLTKALRTVTQEKAELCRAVSQLEK 3008
Cdd:TIGR02169  850 -------KSIEKEIENLNGKKEELEEEL----EELEAALRDLESRLGD-LKKERDELEAQLRELERKIEELEAQIEKKRK 917


                   ...
gi 1953366519 3009 SLK 3011
Cdd:TIGR02169  918 RLS 920
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 2620-2901 5.85e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 5.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2620 ALQELESERGKERALQSRL---EEAQLQHLQREGQSSKTLEELRASLEKQFA-QSSQLCVALKHEQTAKDNLQKELQIEA 2695
Cdd:pfam17380  283 AVSERQQQEKFEKMEQERLrqeKEEKAREVERRRKLEEAEKARQAEMDRQAAiYAEQERMAMERERELERIRQEERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2696 SRC-EALLAQERGQLSELQRsLEAEKGRSLELA----AALRHERLLTEQLSRGPRESP------------AHHALLRKLK 2758
Cdd:pfam17380  363 ERIrQEEIAMEISRMRELER-LQMERQQKNERVrqelEAARKVKILEEERQRKIQQQKvemeqiraeqeeARQREVRRLE 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2759 EEKSRAAEL-----QARLEQVQ--RQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQQQAGLEPLQAGLAAQE 2831
Cdd:pfam17380  442 EERAREMERvrleeQERQQQVErlRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKE 521

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366519 2832 grKDARRADVgpgrADAEMRPTGAKEKLRELEL-QRQRDEHKIRQLQRTVQALEA----KEEAAQRPEAERLQEE 2901
Cdd:pfam17380  522 --MEERQKAI----YEEERRREAEEERRKQQEMeERRRIQEQMRKATEERSRLEAmereREMMRQIVESEKARAE 590
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 192-502 5.95e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 5.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  192 QQQELELAREQHAREQEEMRLRCSQETAKlkeklQSEMERNArAVESLKRDWESERGLCLENLRRElsaKHRSELENL-Q 270
Cdd:pfam17380  297 EQERLRQEKEEKAREVERRRKLEEAEKAR-----QAEMDRQA-AIYAEQERMAMERERELERIRQE---ERKRELERIrQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  271 DQFKRELSEQKaELEKIFQAKNQAECALRT-LEAQHEEALrqLREDLQSERCQYVQDLELRLRDQEVEKQLELESLRASY 349
Cdd:pfam17380  368 EEIAMEISRMR-ELERLQMERQQKNERVRQeLEAARKVKI--LEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEER 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  350 A-ELKAQSQEEIRRlWSQLESPrpdRQDASARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREdpvL 428
Cdd:pfam17380  445 ArEMERVRLEEQER-QQQVERL---RQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRK---L 517

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366519  429 LEQRLQD-ATEEPSLESGGIGPSSMREGERREQRVGPSLQPELAENHRCHLTAWTSSLEAQQQAGLVETQESEGE 502
Cdd:pfam17380  518 LEKEMEErQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2614-2912 6.02e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 6.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2614 ESNLRAALQELESERGKERALQSRLEEA--QLQHLQREGQSSKTLEELRASLEkqfaqssqlcvalKHEQTAKDNLQKEL 2691
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKrqQLERLRREREKAERYQALLKEKR-------------EYEGYELLKEKEAL 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2692 QIEASRCEALLAQERGQLSELQRSLEAekgRSLELAAALRHERLLTEQLSRGPRESPAhhALLRKLKEEKSRAAELQARL 2771
Cdd:TIGR02169  236 ERQKEAIERQLASLEEELEKLTEEISE---LEKRLEEIEQLLEELNKKIKDLGEEEQL--RVKEKIGELEAEIASLERSI 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2772 EQVQRQQEaDVQKRRAELEREKEVRAAQAREPGRCLRreghasQQQAGLEPLQAGLAAQEGRKDARRADVGPGRAD-AEM 2850
Cdd:TIGR02169  311 AEKERELE-DAEERLAKLEAEIDKLLAEIEELEREIE------EERKRRDKLTEEYAELKEELEDLRAELEEVDKEfAET 383

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366519 2851 RPTGAKEKLRELELQRQRDEHK--IRQLQRTVQALEAKEEAAqRPEAERLQEERLGLERVRQQL 2912
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKreLDRLQEELQRLSEELADL-NAAIAGIEAKINELEEEKEDK 446
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1422-1726 6.10e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 6.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1422 HLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPH-----GPRVSDVELLQEKLREKSDGFNEL-------- 1488
Cdd:TIGR04523  222 ELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKikkqlSEKQKELEQNNKKIKELEKQLNQLkseisdln 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1489 ---------VIKKELADRQVMIQE----------------EEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEA 1543
Cdd:TIGR04523  302 nqkeqdwnkELKSELKNQEKKLEEiqnqisqnnkiisqlnEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQS 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1544 LQEKQMSNLLLVSTLQSKLDEgrcpvppADSCPEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNL 1623
Cdd:TIGR04523  382 YKQEIKNLESQINDLESKIQN-------QEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1624 ---ELDAQSSRAAVSVRELQEENASLKAFLQNKEKEImcvsEQLEAQLAgmgsgALREVTYDRSSEIEELRSIIENLREN 1700
Cdd:TIGR04523  455 iikNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL----KSKEKELK-----KLNEEKKELEEKVKDLTKKISSLKEK 525

                          330       340
                   ....*....|....*....|....*....
gi 1953366519 1701 QQRLQKEKAE---EMEQLHEVIERLQEEL 1726
Cdd:TIGR04523  526 IEKLESEKKEkesKISDLEDELNKDDFEL 554
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 593-843 6.31e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 6.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  593 EDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRkaeeeltlmlhdlKEQAEAEKQSVINKFELREIKMRQLQDQQA 672
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA-------------LERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  673 AQILDLEGSLVEQQGRLRQLEHGLEAEecprcghcGQEPAGRVAPADQDWELATRRlredcaLQLMQAQSRFLKERKELT 752
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRL--------GRQPPLALLLSPEDFLDAVRR------LQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  753 EKFTAEQDALLQEAQEKHACDMRLLQERHQQHvlSLTAQLEARRRAEVEELKASVESERWALAE--ARVAELQTEHAAAI 830
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEER--AALEALKAERQKLLARLEKELAELAAELAElqQEAEELEALIARLE 233

                          250
                   ....*....|...
gi 1953366519  831 SALEARHSALLGS 843
Cdd:COG4942    234 AEAAAAAERTPAA 246
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 151-429 7.65e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.25  E-value: 7.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  151 HTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQhareqeEMRLRCSQETA-------KLKE 223
Cdd:COG3096    409 QTRAIQYQQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLEL------EQKLSVADAARrqfekayELVC 482

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  224 KLQSEMERNA---RAVESLkRDWESERGLC--LENLRRELSakhrsELENLQDQfKRELSEQKAELEKIFQAKNQAECAL 298
Cdd:COG3096    483 KIAGEVERSQawqTARELL-RRYRSQQALAqrLQQLRAQLA-----ELEQRLRQ-QQNAERLLEEFCQRIGQQLDAAEEL 555

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519  299 RTLEAQHEEALRQLrEDLQSErcqyvqdlelrLRDQEVEKQLELESLRASYAELKAQ------SQEEIRRLWSQLESPRP 372
Cdd:COG3096    556 EELLAELEAQLEEL-EEQAAE-----------AVEQRSELRQQLEQLRARIKELAARapawlaAQDALERLREQSGEALA 623

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1953366519  373 DRQDASArtpHGEELEQREREcgVQQQRRGRRAEQESELGQSPEGAAERGREDPVLL 429
Cdd:COG3096    624 DSQEVTA---AMQQLLERERE--ATVERDELAARKQALESQIERLSQPGGAEDPRLL 675
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1371-1541 7.80e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.15  E-value: 7.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1371 RKQSEKDRAALLSQMKVFEAELEEQLSRHEacakqaEELSALRQQMAALDKHLRsqrqfmdeqavEREHEREEFQREIQR 1450
Cdd:COG2433    383 EELIEKELPEEEPEAEREKEHEERELTEEE------EEIRRLEEQVERLEAEVE-----------ELEAELEEKDERIER 445

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 1451 LEEQLRQAARPRphgprvsdvellQEKLREksdgfnelvikkelaDRQVMIQEEEIRRLEETNASCRREAAQLREELERQ 1530
Cdd:COG2433    446 LERELSEARSEE------------RREIRK---------------DREISRLDREIERLERELEEERERIEELKRKLERL 498

                          170
                   ....*....|.
gi 1953366519 1531 RDAMKALQQDK 1541
Cdd:COG2433    499 KELWKLEHSGE 509
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2462-2913 9.43e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.03  E-value: 9.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2462 ERLEKVVQEQEKSLEHLrASDRSSLLSEIQALRAQLRMthLQNQEKLQQlcaaltsaeARGSRQEHQLRRQVELLAYKVE 2541
Cdd:pfam15921  267 DRIEQLISEHEVEITGL-TEKASSARSQANSIQSQLEI--IQEQARNQN---------SMYMRQLSDLESTVSQLRSELR 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2542 QEKRIASDvqktlteeqeKASSVRKLLVVEQTVVRDLRSELRECKQDNERllaslgeaqkevlqlrsvLDSKESNLRAAL 2621
Cdd:pfam15921  335 EAKRMYED----------KIEELEKQLVLANSELTEARTERDQFSQESGN------------------LDDQLQKLLADL 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2622 QELESERGKERALQSRLEEaqlqhlqREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNlQKELQIEA------ 2695
Cdd:pfam15921  387 HKREKELSLEKEQNKRLWD-------RDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQG-QMERQMAAiqgkne 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2696 --SRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKeeksraAELQARLEQ 2773
Cdd:pfam15921  459 slEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLR------SRVDLKLQE 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366519 2774 VQRQQEADVQKRRAELEREK-EVRAAQAREPGRCLRREGHASQQQAGLEPLQAGLAAQEgrkdarradvgpgRADAEMRP 2852
Cdd:pfam15921  533 LQHLKNEGDHLRNVQTECEAlKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVE-------------KAQLEKEI 599

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953366519 2853 TGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERlGLERVRQQLL 2913
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVK-DIKQERDQLL 659
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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