NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2565188145|ref|XP_033870629|]
View 

ubiquinone biosynthesis monooxygenase COQ6, mitochondrial-like [Acipenser ruthenus]

Protein Classification

Rossmann-fold NAD(P)-binding domain-containing protein( domain architecture ID 229380)

Rossmann-fold NAD(P)-binding domain-containing protein may function as an oxidoreductase

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
NADB_Rossmann super family cl21454
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ...
 57-484 0e+00

Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.


The actual alignment was detected with superfamily member TIGR01989:

Pssm-ID: 473865 [Multi-domain]  Cd Length: 437  Bit Score: 579.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSLGFDPNLQGKKILLLEAGNKKE------FEVPESYSTRVSSISPGSATLLSGIGAWDHILNM 130
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPKlksrnyEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 131 RCKPFNRMQVWDACSDAMITFDKENLEDEMGYVVENDVVMAALTKQLDAV-SDQVKVQYRSRAVRYTWPLPYQTAESNpW 209
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNGKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPSKYPNDNSN-W 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 210 VQVELASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPTENNVAWQRFLPTGPIALLPLSDSASS 289
Cdd:TIGR01989 160 VHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNST 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 290 LVWSTTHQHATDLLALDDESFVDAINSAF---WSNENHSELIHTAGTVFRSALSLLMPSGTSPRQLPPSVSRVGPKSKAM 366
Cdd:TIGR01989 240 LVWSTSPEEALRLLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 367 FPLGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQRHNLPMMA 446
Cdd:TIGR01989 320 FPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLG 399

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 2565188145 447 AIDILKRLYSTKMAPFVLLRTLGLQATSAVPPLKEQIM 484
Cdd:TIGR01989 400 LVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 57-484 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 579.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSLGFDPNLQGKKILLLEAGNKKE------FEVPESYSTRVSSISPGSATLLSGIGAWDHILNM 130
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPKlksrnyEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 131 RCKPFNRMQVWDACSDAMITFDKENLEDEMGYVVENDVVMAALTKQLDAV-SDQVKVQYRSRAVRYTWPLPYQTAESNpW 209
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNGKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPSKYPNDNSN-W 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 210 VQVELASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPTENNVAWQRFLPTGPIALLPLSDSASS 289
Cdd:TIGR01989 160 VHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNST 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 290 LVWSTTHQHATDLLALDDESFVDAINSAF---WSNENHSELIHTAGTVFRSALSLLMPSGTSPRQLPPSVSRVGPKSKAM 366
Cdd:TIGR01989 240 LVWSTSPEEALRLLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 367 FPLGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQRHNLPMMA 446
Cdd:TIGR01989 320 FPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLG 399

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 2565188145 447 AIDILKRLYSTKMAPFVLLRTLGLQATSAVPPLKEQIM 484
Cdd:TIGR01989 400 LVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
PRK07364 PRK07364
FAD-dependent hydroxylase;
42-480 2.83e-84

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 266.11  E-value: 2.83e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  42 TSEGTAAASSDTDSVYDVIVSGGGMVGTAMACSLgfdpNLQGKKILLLEAgnkkefEVPESYSTR--VSSISPGSATLLS 119
Cdd:PRK07364    4 TAATSPTLPSTRSLTYDVAIVGGGIVGLTLAAAL----KDSGLRIALIEA------QPAEAAAAKgqAYALSLLSARIFE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 120 GIGAWDHILNmRCKPFNRMQVWDACSDAMITFDKENL-EDEMGYVVENDVVMAALTKQLDAvSDQVKVQYRSRAVRYTwp 198
Cdd:PRK07364   74 GIGVWEKILP-QIGKFRQIRLSDADYPGVVKFQPTDLgTEALGYVGEHQVLLEALQEFLQS-CPNITWLCPAEVVSVE-- 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 199 lpYQTAESNpwVQVELASG-QQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPtENNVAWQRFLPTGP 277
Cdd:PRK07364  150 --YQQDAAT--VTLEIEGKqQTLQSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHEAP-HNDIAYERFWPSGP 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 278 IALLPLSDSASSLVWSTTHQHATDLLALDDESFVDAINSafwsnenhseliHTAGtvFRSALSLLmpsgtSPRQLppsvs 357
Cdd:PRK07364  225 FAILPLPGNRCQIVWTAPHAQAKALLALPEAEFLAELQQ------------RYGD--QLGKLELL-----GDRFL----- 280

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 358 rvgpkskamFPLGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETER 437
Cdd:PRK07364  281 ---------FPVQLMQSDRYVQHRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQVLQTAHQRGEDIGSLAVLKRYERWR 351

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 2565188145 438 QRHNLPMMAAIDILKRLYSTKMAPFVLLRTLGLQATSAVPPLK 480
Cdd:PRK07364  352 KRENWLILGFTDLLDRLFSNQWWPLVVVRRLGLWLLRHVPPLK 394
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 57-480 1.26e-54

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 185.91  E-value: 1.26e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSLGfdpnLQGKKILLLEAgnkkefEVPESYSTRVSSISPGSATLLSGIGAWDHILnMRCKPFN 136
Cdd:COG0654     4 TDVLIVGGGPAGLALALALA----RAGIRVTVVER------APPPRPDGRGIALSPRSLELLRRLGLWDRLL-ARGAPIR 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 137 RMQVWDACSDAMIT-FDKENLEDEMGYVVENDVVMAALTKQLDAvsDQVKVQYRSRAVRYTwplpyQTAESnpwVQVELA 215
Cdd:COG0654    73 GIRVRDGSDGRVLArFDAAETGLPAGLVVPRADLERALLEAARA--LGVELRFGTEVTGLE-----QDADG---VTVTLA 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 216 SGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHlseptennVAWQRFLptgpiallplsdsasslvwSTT 295
Cdd:COG0654   143 DGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVR--------TELRARL-------------------AAA 195

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 296 HQHATDLLALDDESFvdainsafwsnenhselihtagtvfrsalsllmpsgtsprqlppsvsrvgpkskamFPLGLGHAS 375
Cdd:COG0654   196 GPRLGELLELSPRSA--------------------------------------------------------FPLRRRRAE 219

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 376 EYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGAtrhLLEYETERQRHNLPMMAAIDILKRLY 455
Cdd:COG0654   220 RWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAALRGRDDEAA---LARYERERRPRAARVQRAADALGRLF 296

                         410       420
                  ....*....|....*....|....*
gi 2565188145 456 STKMAPFVLLRTLGLQATSAVPPLK 480
Cdd:COG0654   297 HPDSPPLRLLRNAGLRLLDRLPPLK 321
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 57-440 1.48e-09

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 59.65  E-value: 1.48e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSLGfdpnLQGKKILLLEAGNKKefevpeSYSTRVSSISPGSATLLSGIGAWDHILNMrCKPFN 136
Cdd:pfam01494   2 TDVLIVGGGPAGLMLALLLA----RAGVRVVLVERHATT------SVLPRAHGLNQRTMELLRQAGLEDRILAE-GVPHE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 137 RMQVWDACSDAMItfdkeNLEDEMGYVVENDVVMAALTKQL--DAVSDQVKVQyrsRAVRYTWPLPYQTAESNPWVQVEL 214
Cdd:pfam01494  71 GMGLAFYNTRRRA-----DLDFLTSPPRVTVYPQTELEPILveHAEARGAQVR---FGTEVLSLEQDGDGVTAVVRDRRD 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 215 ASGQQLQTKLLIGADGPNSTVRKAAGMQ-----TVQWNyEQSAVVAVLHLSEPTENN--VAWQRFLPTGPIALLPlsdsa 287
Cdd:pfam01494 143 GEEYTVRAKYLVGCDGGRSPVRKTLGIEfegfeGVPFG-SLDVLFDAPDLSDPVERAfvHYLIYAPHSRGFMVGP----- 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 288 sslVWSTTHQHATDLLALDDESfvdainsAFWSNEnhselihtagtVFRSALSLLMPSGTSPRQLPPSVSRvgpksKAMF 367
Cdd:pfam01494 217 ---WRSAGRERYYVQVPWDEEV-------EERPEE-----------FTDEELKQRLRSIVGIDLALVEILW-----KSIW 270

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2565188145 368 PLGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSqAAFDGRdlgATRHLLE-YETERQRH 440
Cdd:pfam01494 271 GVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLA-AVLRGQ---AGESLLDtYSAERLPV 340
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 57-484 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 579.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSLGFDPNLQGKKILLLEAGNKKE------FEVPESYSTRVSSISPGSATLLSGIGAWDHILNM 130
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPKlksrnyEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 131 RCKPFNRMQVWDACSDAMITFDKENLEDEMGYVVENDVVMAALTKQLDAV-SDQVKVQYRSRAVRYTWPLPYQTAESNpW 209
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNGKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPSKYPNDNSN-W 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 210 VQVELASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPTENNVAWQRFLPTGPIALLPLSDSASS 289
Cdd:TIGR01989 160 VHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNST 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 290 LVWSTTHQHATDLLALDDESFVDAINSAF---WSNENHSELIHTAGTVFRSALSLLMPSGTSPRQLPPSVSRVGPKSKAM 366
Cdd:TIGR01989 240 LVWSTSPEEALRLLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 367 FPLGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQRHNLPMMA 446
Cdd:TIGR01989 320 FPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLG 399

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 2565188145 447 AIDILKRLYSTKMAPFVLLRTLGLQATSAVPPLKEQIM 484
Cdd:TIGR01989 400 LVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 58-488 1.14e-158

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 455.12  E-value: 1.14e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  58 DVIVSGGGMVGTAMACSLGFDpnlqGKKILLLEAGNKKEFeVPESYSTRVSSISPGSATLLSGIGAWDHILNMRCKPFNR 137
Cdd:TIGR01988   1 DIVIVGGGMVGLALALALARS----GLKVALIEATPLPAP-ADPGFDNRVSALSAASIRLLEKLGVWDKIEPARAQPIRD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 138 MQVWDACSDAMITFDKENL-EDEMGYVVENDVVMAALTKQLDAvsdqvkvqyrSRAVRYTWPLPYQTAESNP-WVQVELA 215
Cdd:TIGR01988  76 IHVSDGGSFGALRFDADEIgLEALGYVVENRVLQQALWERLQE----------LPNVTLLCPARVVELPRHSdHVELTLD 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 216 SGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPTeNNVAWQRFLPTGPIALLPLSDSASSLVWSTT 295
Cdd:TIGR01988 146 DGQQLRARLLVGADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPH-QGTAWERFTPTGPLALLPLPDNRSSLVWTLP 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 296 HQHATDLLALDDESFVDAINSAFWSnenhselihtagtvfrsalsllmpsgtsprQLPPSVSrvgPKSKAMFPLGLGHAS 375
Cdd:TIGR01988 225 PEEAERLLALSDEEFLAELQRAFGS------------------------------RLGAITL---VGERHAFPLSLTHAK 271

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 376 EYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQRHNLPMMAAIDILKRLY 455
Cdd:TIGR01988 272 RYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLRVLQRYERRRRFDNAAMLGATDGLNRLF 351

                         410       420       430
                  ....*....|....*....|....*....|...
gi 2565188145 456 STKMAPFVLLRTLGLQATSAVPPLKEQIMAFAS 488
Cdd:TIGR01988 352 SNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAM 384
PRK07364 PRK07364
FAD-dependent hydroxylase;
42-480 2.83e-84

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 266.11  E-value: 2.83e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  42 TSEGTAAASSDTDSVYDVIVSGGGMVGTAMACSLgfdpNLQGKKILLLEAgnkkefEVPESYSTR--VSSISPGSATLLS 119
Cdd:PRK07364    4 TAATSPTLPSTRSLTYDVAIVGGGIVGLTLAAAL----KDSGLRIALIEA------QPAEAAAAKgqAYALSLLSARIFE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 120 GIGAWDHILNmRCKPFNRMQVWDACSDAMITFDKENL-EDEMGYVVENDVVMAALTKQLDAvSDQVKVQYRSRAVRYTwp 198
Cdd:PRK07364   74 GIGVWEKILP-QIGKFRQIRLSDADYPGVVKFQPTDLgTEALGYVGEHQVLLEALQEFLQS-CPNITWLCPAEVVSVE-- 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 199 lpYQTAESNpwVQVELASG-QQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPtENNVAWQRFLPTGP 277
Cdd:PRK07364  150 --YQQDAAT--VTLEIEGKqQTLQSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHEAP-HNDIAYERFWPSGP 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 278 IALLPLSDSASSLVWSTTHQHATDLLALDDESFVDAINSafwsnenhseliHTAGtvFRSALSLLmpsgtSPRQLppsvs 357
Cdd:PRK07364  225 FAILPLPGNRCQIVWTAPHAQAKALLALPEAEFLAELQQ------------RYGD--QLGKLELL-----GDRFL----- 280

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 358 rvgpkskamFPLGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETER 437
Cdd:PRK07364  281 ---------FPVQLMQSDRYVQHRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQVLQTAHQRGEDIGSLAVLKRYERWR 351

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 2565188145 438 QRHNLPMMAAIDILKRLYSTKMAPFVLLRTLGLQATSAVPPLK 480
Cdd:PRK07364  352 KRENWLILGFTDLLDRLFSNQWWPLVVVRRLGLWLLRHVPPLK 394
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 58-487 2.49e-82

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 260.47  E-value: 2.49e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  58 DVIVSGGGMVGTAMACSLGfDPNLqgkKILLLEaGNKKEFEVPESYSTRVSSISPGSATLLSGIGAWDHILNMRCKPFNR 137
Cdd:PRK08850    6 DVAIIGGGMVGLALAAALK-ESDL---RIAVIE-GQLPEEALNELPDVRVSALSRSSEHILRNLGAWQGIEARRAAPYIA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 138 MQVWDACSDAMITFDKENL-EDEMGYVVENDVVMAALtkqLDAVSDQVKVQYRSRAVRYTwplpYQTAESNPWVQVElaS 216
Cdd:PRK08850   81 MEVWEQDSFARIEFDAESMaQPDLGHIVENRVIQLAL---LEQVQKQDNVTLLMPARCQS----IAVGESEAWLTLD--N 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 217 GQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPtENNVAWQRFLPTGPIALLPLSDS-ASSLVWSTT 295
Cdd:PRK08850  152 GQALTAKLVVGADGANSWLRRQMDIPLTHWDYGHSALVANVRTVDP-HNSVARQIFTPQGPLAFLPMSEPnMSSIVWSTE 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 296 HQHATDLLALDDESFVDAINSAFwsnENHSELIHTAGTvfRSAlsllmpsgtsprqlppsvsrvgpkskamFPLGLGHAS 375
Cdd:PRK08850  231 PLRAEALLAMSDEQFNKALTAEF---DNRLGLCEVVGE--RQA----------------------------FPLKMRYAR 277

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 376 EYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQRHNLPMMAAIDILKRLY 455
Cdd:PRK08850  278 DFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQEILALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGFRDLF 357

                         410       420       430
                  ....*....|....*....|....*....|..
gi 2565188145 456 STKMAPFVLLRTLGLQATSAVPPLKEQIMAFA 487
Cdd:PRK08850  358 SGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRA 389
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 52-487 1.52e-81

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 257.99  E-value: 1.52e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  52 DTDSVYDVIVSGGGMVGTAMACSLGfdpnLQGKKILLLEAGNKKEFeVPESY-STRVSSISPGSATLLSGIGAWDHILNM 130
Cdd:PRK08020    1 MTNQPTDIAIVGGGMVGAALALGLA----QHGFSVAVLEHAAPAPF-DADSQpDVRISAISAASVALLKGLGVWDAVQAM 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 131 RCKPFNRMQVWDAcSDAMITFDKENLE-DEMGYVVENDVVMAALTKQLDAvsdQVKVQYRSRAVrytwpLPYQTAESNPW 209
Cdd:PRK08020   76 RSHPYRRLETWEW-ETAHVVFDAAELKlPELGYMVENRVLQLALWQALEA---HPNVTLRCPAS-----LQALQRDDDGW 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 210 vQVELASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPTEnNVAWQRFLPTGPIALLPLSDSASS 289
Cdd:PRK08020  147 -ELTLADGEEIQAKLVIGADGANSQVRQMAGIGVHGWQYRQSCMLISVKCENPPG-DSTWQQFTPSGPRAFLPLFDNWAS 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 290 LVWSTTHQHATDLLALDDESFVDAINSAFwsnenhselihtagtvfrsalsllmpsgtsprqlPPSVSRVGPKSKAMFPL 369
Cdd:PRK08020  225 LVWYDSPARIRQLQAMSMAQLQQEIAAHF----------------------------------PARLGAVTPVAAGAFPL 270

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 370 GLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQRHNLPMMAAID 449
Cdd:PRK08020  271 TRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVLVNARSYGEAWASEAVLKRYQRRRMADNLLMQSGMD 350

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 2565188145 450 ILKRLYSTKMAPFVLLRTLGLQATSAVPPLKEQIMAFA 487
Cdd:PRK08020  351 LFYAGFSNNLPPLRFARNLGLMAAQRAGVLKRQALKYA 388
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
57-488 2.28e-81

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 257.58  E-value: 2.28e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSLGfdpnLQGKKILLLEAGNKKEfEVPESYSTRVSSISPGSATLLSGIGAWDHILNMRCKPFN 136
Cdd:PRK07608    6 FDVVVVGGGLVGASLALALA----QSGLRVALLAPRAPPR-PADDAWDSRVYAISPSSQAFLERLGVWQALDAARLAPVY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 137 RMQVW-DAcsDAMITFDK-ENLEDEMGYVVENDVVMAALTKQLdavSDQVKVQ-YRSRAVRYTWplpyqTAESnpwVQVE 213
Cdd:PRK07608   81 DMRVFgDA--HARLHFSAyQAGVPQLAWIVESSLIERALWAAL---RFQPNLTwFPARAQGLEV-----DPDA---ATLT 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 214 LASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPtENNVAWQRFLPTGPIALLPLSDSASSLVWS 293
Cdd:PRK07608  148 LADGQVLRADLVVGADGAHSWVRSQAGIKAERRPYRQTGVVANFKAERP-HRGTAYQWFRDDGILALLPLPDGHVSMVWS 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 294 TTHQHATDLLALDDESFVDAINSAfwsnenhseLIHTAGtvfrsALSLLMPSgtsprqlppsvsrvgpkskAMFPLGLGH 373
Cdd:PRK07608  227 ARTAHADELLALSPEALAARVERA---------SGGRLG-----RLECVTPA-------------------AGFPLRLQR 273

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 374 ASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAfDGRDLGATRHLLEYETERQRHNLPMMAAIDILKR 453
Cdd:PRK07608  274 VDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLAGRE-PFRDLGDLRLLRRYERARREDILALQVATDGLQR 352

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 2565188145 454 LYSTKMAPFVLLRTLGLQATSAVPPLKEQIMAFAS 488
Cdd:PRK07608  353 LFALPGPLARWLRNAGMALVGALPLVKRWLVRHAL 387
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 58-483 2.44e-80

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 254.55  E-value: 2.44e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  58 DVIVSGGGMVGTAMACSLGfdpNLQGKKILLLEAGNKKEfeVPESYSTRVSSISPGSATLLSGIGAWDHILNMRCkPFNR 137
Cdd:TIGR01984   1 DVIIVGGGLVGLSLALALS---RLGKIKIALIEANSPSA--AQPGFDARSLALSYGSKQILEKLGLWPKLAPFAT-PILD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 138 MQVWDACSDAMITFDKENL-EDEMGYVVENDVVMAALTKQLDavsdqvkvqyRSRAVRYTWPLPYQTAESNP-WVQVELA 215
Cdd:TIGR01984  75 IHVSDQGHFGATHLRASEFgLPALGYVVELADLGQALLSRLA----------LLTNIQLYCPARYKEIIRNQdYVRVTLD 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 216 SGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPTENnVAWQRFLPTGPIALLPLSD-SASSLVWST 294
Cdd:TIGR01984 145 NGQQLRAKLLIAADGANSKVRELLSIPTEEHDYNQTALIANIRHEQPHQG-CAFERFTPHGPLALLPLKDnYRSSLVWCL 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 295 THQHATDLLALDDESFVDAINSAF-WSnenhselihtAGtvfrsalsllmpsgtsprqlppSVSRVGPKSkaMFPLGLGH 373
Cdd:TIGR01984 224 PSKQADTIANLPDAEFLAELQQAFgWR----------LG----------------------KITQVGERK--TYPLKLRI 269

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 374 ASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAfdgRDLGATRHLLEYETERQRHNLPMMAAIDILKR 453
Cdd:TIGR01984 270 AETHVHPRVVLIGNAAQTLHPIAGQGFNLGLRDVETLAEVLIDAR---IDLGTYALLQEYLRRRQFDQFITIGLTDGLNR 346

                         410       420       430
                  ....*....|....*....|....*....|
gi 2565188145 454 LYSTKMAPFVLLRTLGLQATSAVPPLKEQI 483
Cdd:TIGR01984 347 LFSNHIPLLRALRNLGLLALENFPPLKKRL 376
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 58-480 3.43e-80

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 255.14  E-value: 3.43e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  58 DVIVSGGGMVGTAMACSLgfdpNLQGKKILLLEAG--NKKEFEVPESYSTRVSSISPGSATLLSGIGAWDHILNMRCKPF 135
Cdd:PRK05714    4 DLLIVGAGMVGSALALAL----QGSGLEVLLLDGGplSVKPFDPQAPFEPRVSALSAASQRILERLGAWDGIAARRASPY 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 136 NRMQVWDACSDAMITFDKENLEDE-MGYVVENDVVMAALTKQLDAVSDQVKVQYRSRAVRYTwplpyqtaeSNPWvQVEL 214
Cdd:PRK05714   80 SEMQVWDGSGTGQIHFSAASVHAEvLGHIVENRVVQDALLERLHDSDIGLLANARLEQMRRS---------GDDW-LLTL 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 215 ASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPtENNVAWQRFLPTGPIALLPLSDSAS----SL 290
Cdd:PRK05714  150 ADGRQLRAPLVVAADGANSAVRRLAGCATREWDYLHHAIVTSVRCSEP-HRATAWQRFTDDGPLAFLPLERDGDehwcSI 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 291 VWSTTHQHATDLLALDDESFVDAINSAFwsnENHselihtAGTVFRSalsllmpsgtSPRQLPPSVSRvgpkskamfplg 370
Cdd:PRK05714  229 VWSTTPEEAERLMALDDDAFCAALERAF---EGR------LGEVLSA----------DPRLCVPLRQR------------ 277

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 371 lgHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQRHNLPMMAAIDI 450
Cdd:PRK05714  278 --HAKRYVEPGLALIGDAAHTIHPLAGQGVNLGFLDAAVLAEVLLHAAERGERLADVRVLSRFERRRMPHNLALMAAMEG 355

                         410       420       430
                  ....*....|....*....|....*....|
gi 2565188145 451 LKRLYSTKMAPFVLLRTLGLQATSAVPPLK 480
Cdd:PRK05714  356 FERLFQADPLPLRWLRNTGLKLVDQMPEAK 385
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 57-487 4.53e-73

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 235.82  E-value: 4.53e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMAcsLGFDPnlQGKKILLLEAGNKKEFEVPESYSTRVSSISPGSATLLSGIGAWDHILNMRCKPFN 136
Cdd:PRK08849    4 YDIAVVGGGMVGAATA--LGFAK--QGRSVAVIEGGEPKAFEPSQPMDIRVSAISQTSVDLLESLGAWSSIVAMRVCPYK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 137 RMQVWDAcSDAMITFDKENLE-DEMGYVVENDVVMAALTKQLDAVsDQVKVQYRSRAVRYTWplpyqTAESNpwvQVELA 215
Cdd:PRK08849   80 RLETWEH-PECRTRFHSDELNlDQLGYIVENRLIQLGLWQQFAQY-PNLTLMCPEKLADLEF-----SAEGN---RVTLE 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 216 SGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPtENNVAWQRFLPTGPIALLPLSDSASSLVWSTT 295
Cdd:PRK08849  150 SGAEIEAKWVIGADGANSQVRQLAGIGITAWDYRQHCMLINVETEQP-QQDITWQQFTPSGPRSFLPLCGNQGSLVWYDS 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 296 HQHATDLLALDDESFvdainsafwsnenHSELIhtagtvfrsalsllmpsgtspRQLPPSVSRVGPKSKAMFPLGLGHAS 375
Cdd:PRK08849  229 PKRIKQLSAMNPEQL-------------RSEIL---------------------RHFPAELGEIKVLQHGSFPLTRRHAQ 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 376 EYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLtrhLSQAafDGRDLGATRHLLEYETERQRHNLPMMAAIDILKRLY 455
Cdd:PRK08849  275 QYVKNNCVLLGDAAHTINPLAGQGVNLGFKDVDVL---LAET--EKQGVLNDASFARYERRRRPDNLLMQTGMDLFYKTF 349

                         410       420       430
                  ....*....|....*....|....*....|..
gi 2565188145 456 STKMAPFVLLRTLGLQATSAVPPLKEQIMAFA 487
Cdd:PRK08849  350 SNSLTPLKFVRNAALKLAENSGPLKTQVLKYA 381
PRK08013 PRK08013
oxidoreductase; Provisional
 57-484 1.30e-69

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 227.62  E-value: 1.30e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSLgfdpnlQGK--KILLLEAGNKKEFEVPESYSTRVSSISPGSATLLSGIGAWDHILNMRCKP 134
Cdd:PRK08013    4 VDVVIAGGGMVGLAVACGL------QGSglRVAVLEQRVPEPLAADAPPALRVSAINAASEKLLTRLGVWQDILARRASC 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 135 FNRMQVWDACSDAMITFD-KENLEDEMGYVVENDVVMAALTKQLDAVSDqVKVQYRSRAVRYTWplpyqtAESNPWVQve 213
Cdd:PRK08013   78 YHGMEVWDKDSFGRIAFDdQSMGYSHLGHIIENSVIHYALWQKAQQSSD-ITLLAPAELQQVAW------GENEAFLT-- 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 214 LASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPtENNVAWQRFLPTGPIALLPLSDS-ASSLVW 292
Cdd:PRK08013  149 LKDGSMLTARLVVGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEP-HDAVARQVFHGDGILAFLPLSDPhLCSIVW 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 293 STTHQHATDLLALDDESFVDAINSAFwsnenhselihtagtVFRSALSLLMpsgtSPRQLppsvsrvgpkskamFPLGLG 372
Cdd:PRK08013  228 SLSPEEAQRMQQAPEEEFNRALAIAF---------------DNRLGLCELE----SERQV--------------FPLTGR 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 373 HASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQRHNLPMMAAIDILK 452
Cdd:PRK08013  275 YARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELRRLHRQGKDIGQHLYLRRYERSRKHSAALMLAGMQGFR 354

                         410       420       430
                  ....*....|....*....|....*....|..
gi 2565188145 453 RLYSTKMAPFVLLRTLGLQATSAVPPLKEQIM 484
Cdd:PRK08013  355 DLFAGNNPAKKLLRDIGLKLADTLPGVKPQLI 386
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
58-479 1.56e-68

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 224.36  E-value: 1.56e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  58 DVIVSGGGMVGTAMACSLgfdpNLQGKKILLLEAGNKKEFEvPESYSTRVSSISPGSATLLSGIGAWDHILNMRCKPFNR 137
Cdd:PRK08773    8 DAVIVGGGVVGAACALAL----ADAGLSVALVEGREPPRWQ-ADQPDLRVYAFAADNAALLDRLGVWPAVRAARAQPYRR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 138 MQVWDACSDAMITFDKENL-EDEMGYVVENDVVMAALTKQLDAVSDQVKVQYRSRAVRytwplpyQTAESnpwVQVELAS 216
Cdd:PRK08773   83 MRVWDAGGGGELGFDADTLgREQLGWIVENDLLVDRLWAALHAAGVQLHCPARVVALE-------QDADR---VRLRLDD 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 217 GQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPTENNvAWQRFLPTGPIALLPLSDSASSLVWSTTH 296
Cdd:PRK08773  153 GRRLEAALAIAADGAASTLRELAGLPVSRHDYAQRGVVAFVDTEHPHQAT-AWQRFLPTGPLALLPFADGRSSIVWTLPD 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 297 QHATDLLALDDESFVDAINSAFWSNENHSELIhtagtvfrsalsllmpsgtSPRqlppsvsrvgpkskAMFPLGLGHASE 376
Cdd:PRK08773  232 AEAERVLALDEAAFSRELTQAFAARLGEVRVA-------------------SPR--------------TAFPLRRQLVQQ 278

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 377 YIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQRHNLPMMAAIDILKRLYS 456
Cdd:PRK08773  279 YVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAHARRADWAAPHRLQRWARTRRSDNTVAAYGFDAINRVFS 358

                         410       420
                  ....*....|....*....|...
gi 2565188145 457 TKMAPFVLLRTLGLQATSAVPPL 479
Cdd:PRK08773  359 NDEMHLTLLRGSVLGLAGKLPPL 381
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 57-480 2.04e-66

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 218.95  E-value: 2.04e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSLgfDPNLQGK-KILLLEAgNKKEFEVPESYSTRVSSISPGSATLLSGIGAWDHIlNMRCKPF 135
Cdd:PRK05732    4 MDVIIVGGGMAGATLALAL--SRLSHGGlPVALIEA-FAPESDAHPGFDARAIALAAGTCQQLARLGVWQAL-ADCATPI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 136 NRMQVWDACSDAMITFDKENLE-DEMGYVVENDVVMAALTKQLDAvSDQVKVQYRSRAVRYTwplpyQTAESnpwVQVEL 214
Cdd:PRK05732   80 THIHVSDRGHAGFVRLDAEDYGvPALGYVVELHDVGQRLFALLDK-APGVTLHCPARVANVE-----RTQGS---VRVTL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 215 ASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPtENNVAWQRFLPTGPIALLPLSDSASSLVWST 294
Cdd:PRK05732  151 DDGETLTGRLLVAADGSHSALREALGIDWQQHPYEQVAVIANVTTSEA-HQGRAFERFTEHGPLALLPMSDGRCSLVWCH 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 295 THQHATDLLALDDESFVDAINSAF-WSnenhselihtAGTvfrsalsllmpsgtsprqlppsVSRVGPKSkaMFPLGLGH 373
Cdd:PRK05732  230 PLEDAEEVLSWSDAQFLAELQQAFgWR----------LGR----------------------ITHAGKRS--AYPLALVT 275

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 374 ASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQ--RHNLPMMAaiDIL 451
Cdd:PRK05732  276 AAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQALARGEDIGDYAVLQRYQQRRQqdREATIGFT--DGL 353

                         410       420
                  ....*....|....*....|....*....
gi 2565188145 452 KRLYSTKMAPFVLLRTLGLQATSAVPPLK 480
Cdd:PRK05732  354 VRLFANRWAPLVVGRNLGLMAMDLLPPAR 382
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
57-481 2.51e-65

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 216.38  E-value: 2.51e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSL-GFDPNLqgkKILLLEAGnkkeFEVPESYSTRVSSISPGSATLLSGIGAWDHIlNMRCKPF 135
Cdd:PRK07333    2 CDVVIAGGGYVGLALAVALkQAAPHL---PVTVVDAA----PAGAWSRDPRASAIAAAARRMLEALGVWDEI-APEAQPI 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 136 NRMQVWDA-CSDA----MITFDKENLEDE-MGYVVENDVVMAALTKQLDAVsdQVKVQYRSRAVRYTwplpyQTAESnpw 209
Cdd:PRK07333   74 TDMVITDSrTSDPvrpvFLTFEGEVEPGEpFAHMVENRVLINALRKRAEAL--GIDLREATSVTDFE-----TRDEG--- 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 210 VQVELASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSA-VVAVLHlsEPTENNVAWQRFLPTGPIALLPLSDSAS 288
Cdd:PRK07333  144 VTVTLSDGSVLEARLLVAADGARSKLRELAGIKTVGWDYGQSGiVCTVEH--ERPHGGRAEEHFLPAGPFAILPLKGNRS 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 289 SLVWSTTHQHATDLLALDDESFVDAINSAFWsnenhseliHTAGTVfrsalsllmpsgtsprqlppsvsRVGPKSKAmFP 368
Cdd:PRK07333  222 SLVWTERTADAERLVALDDLVFEAELEQRFG---------HRLGEL-----------------------KVLGKRRA-FP 268

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 369 LGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQRHNLPMMAAI 448
Cdd:PRK07333  269 LGLTLARSFVAPRFALVGDAAHGIHPIAGQGLNLGLKDVAALAEVVVEAARLGLDIGSLDVLERYQRWRRFDTVRMGVTT 348

                         410       420       430
                  ....*....|....*....|....*....|...
gi 2565188145 449 DILKRLYSTKMAPFVLLRTLGLQATSAVPPLKE 481
Cdd:PRK07333  349 DVLNRLFSNDSTLLRSVRDIGLGLVDRLPKLKS 381
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 57-480 1.26e-54

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 185.91  E-value: 1.26e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSLGfdpnLQGKKILLLEAgnkkefEVPESYSTRVSSISPGSATLLSGIGAWDHILnMRCKPFN 136
Cdd:COG0654     4 TDVLIVGGGPAGLALALALA----RAGIRVTVVER------APPPRPDGRGIALSPRSLELLRRLGLWDRLL-ARGAPIR 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 137 RMQVWDACSDAMIT-FDKENLEDEMGYVVENDVVMAALTKQLDAvsDQVKVQYRSRAVRYTwplpyQTAESnpwVQVELA 215
Cdd:COG0654    73 GIRVRDGSDGRVLArFDAAETGLPAGLVVPRADLERALLEAARA--LGVELRFGTEVTGLE-----QDADG---VTVTLA 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 216 SGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHlseptennVAWQRFLptgpiallplsdsasslvwSTT 295
Cdd:COG0654   143 DGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVR--------TELRARL-------------------AAA 195

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 296 HQHATDLLALDDESFvdainsafwsnenhselihtagtvfrsalsllmpsgtsprqlppsvsrvgpkskamFPLGLGHAS 375
Cdd:COG0654   196 GPRLGELLELSPRSA--------------------------------------------------------FPLRRRRAE 219

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 376 EYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGAtrhLLEYETERQRHNLPMMAAIDILKRLY 455
Cdd:COG0654   220 RWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAALRGRDDEAA---LARYERERRPRAARVQRAADALGRLF 296

                         410       420
                  ....*....|....*....|....*
gi 2565188145 456 STKMAPFVLLRTLGLQATSAVPPLK 480
Cdd:COG0654   297 HPDSPPLRLLRNAGLRLLDRLPPLK 321
PRK09126 PRK09126
FAD-dependent hydroxylase;
57-483 3.10e-51

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 178.60  E-value: 3.10e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSLGFDpnlqGKKILLLEAGNKKEFEVPeSYSTRVSSISPGSATLLSGIGAWDHILNMRCKPFN 136
Cdd:PRK09126    4 SDIVVVGAGPAGLSFARSLAGS----GLKVTLIERQPLAALADP-AFDGREIALTHASREILQRLGAWDRIPEDEISPLR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 137 RMQVWDACSDAMITFD-KENLEDEMGYVVENDVVMAALtkqLDAVSDQVKVQYRS-RAVRYTWPLPyqtaesnPWVQVEL 214
Cdd:PRK09126   79 DAKVLNGRSPFALTFDaRGRGADALGYLVPNHLIRRAA---YEAVSQQDGIELLTgTRVTAVRTDD-------DGAQVTL 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 215 ASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPtENNVAWQRFLPTGPIALLPLSDSASSLVWST 294
Cdd:PRK09126  149 ANGRRLTARLLVAADSRFSATRRQLGIGADMHDFGRTMLVCRMRHELP-HHHTAWEWFGYGQTLALLPLNGHLSSLVLTL 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 295 THQHATDLLALDDESFvdainsafwsNENHSELihtagtvFRSALSLLMPSGTsprqlppsvsrvgpksKAMFPLGLGHA 374
Cdd:PRK09126  228 PPDQIEALLALDPEAF----------AAEVTAR-------FKGRLGAMRLVSS----------------RHAYPLVAVYA 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 375 SEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLGATRHLLEYETERQRHNLPMMAAIDILKRL 454
Cdd:PRK09126  275 HRFVAKRFALIGDAAVGMHPVTAHGFNLGLKGQDILARLILAAARRGQDIGAASLLERYERKHRLATRPLYHATNAIAAL 354

                         410       420
                  ....*....|....*....|....*....
gi 2565188145 455 YSTKMAPFVLLRTLGLQATSAVPPLKEQI 483
Cdd:PRK09126  355 YTDDRPPARLLRRAVLRAANRFPPLKQAI 383
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
49-483 3.15e-42

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 154.85  E-value: 3.15e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  49 ASSDTDSVYDVIVSGGGMVGTAMACSLGFDPNLQGKKILLLEAgnkKEFEVPESySTRVSSISPGSATLLSGIGAW---- 124
Cdd:PRK06996    4 AASMAAPDFDIAIVGAGPVGLALAGWLARRSATRALSIALIDA---REPAASAN-DPRAIALSHGSRVLLETLGAWpada 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 125 ---DHILNMRCKPFNRmqvwdacsdAMITFDKENLEdEMGYVVENDVVMAALTKQLDAVSDQVKVQYRSRAvrytwplPY 201
Cdd:PRK06996   80 tpiEHIHVSQRGHFGR---------TLIDRDDHDVP-ALGYVVRYGSLVAALARAVRGTPVRWLTSTTAHA-------PA 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 202 QTAESNPWVQVELASGQQLQTKLLIGADGP-NSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPTENnVAWQRFLPTGPIAL 280
Cdd:PRK06996  143 QDADGVTLALGTPQGARTLRARIAVQAEGGlFHDQKADAGDSARRRDYGQTAIVGTVTVSAPRPG-WAWERFTHEGPLAL 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 281 LPLSDSAS---SLVWSTTHQHATDLLALDDESFVDAINSAFwsnenhselihtagtvfrsalsllmpsGTSPRQLppsvS 357
Cdd:PRK06996  222 LPLGGPRQadyALVWCCAPDEAARRAALPDDAFLAELGAAF---------------------------GTRMGRF----T 270

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 358 RVGPKskAMFPLGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRDLG--ATRHLLEYET 435
Cdd:PRK06996  271 RIAGR--HAFPLGLNAARTLVNGRIAAVGNAAQTLHPVAGQGLNLGLRDAHTLADALSDHGATPLALAtfAARRALDRRV 348

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 2565188145 436 erqrhnlpMMAAIDILKRLYSTKMAPFVLLRTLGLQATSAVPPLKEQI 483
Cdd:PRK06996  349 --------TIGATDLLPRLFTVDSRPLAHLRGAALTALEFVPPLKHAL 388
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
50-484 4.56e-40

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 148.51  E-value: 4.56e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  50 SSDTDSVYDVIVSGGGMVGTAMACSL---GFDPNLQGKKillleagnkkefevPESYSTRVSSISPGSATLLSGIGAWDH 126
Cdd:PRK07494    1 SLMEKEHTDIAVIGGGPAGLAAAIALaraGASVALVAPE--------------PPYADLRTTALLGPSIRFLERLGLWAR 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 127 IlnmRCK--PFNRMQVWDACSD----AMITFDKENL-EDEMGYVVENDVVMAALTKQLDAVSDQVKVQYRSRAVRYtwpl 199
Cdd:PRK07494   67 L---APHaaPLQSMRIVDATGRliraPEVRFRAAEIgEDAFGYNIPNWLLNRALEARVAELPNITRFGDEAESVRP---- 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 200 pyQTAEsnpwVQVELASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVV-AVLHlSEPTEnNVAWQRFLPTGPI 278
Cdd:PRK07494  140 --REDE----VTVTLADGTTLSARLVVGADGRNSPVREAAGIGVRTWSYPQKALVlNFTH-SRPHQ-NVSTEFHTEGGPF 211

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 279 ALLPLSDSASSLVWSTTHQHATDLLALDDESFVDAINsafwsNENHSELihtaGTVfrsalsllmpSGTSPRQLppsvsr 358
Cdd:PRK07494  212 TQVPLPGRRSSLVWVVRPAEAERLLALSDAALSAAIE-----ERMQSML----GKL----------TLEPGRQA------ 266

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 359 vgpkskamFPLGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQaafDGRDLGATRHLLEYETERQ 438
Cdd:PRK07494  267 --------WPLSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLGLRDVATLVEIVED---RPEDPGSAAVLAAYDRARR 335

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 2565188145 439 RHNLPMMAAIDILKRLYSTKMAPFVLLRTLGLQATSAVPPLKEQIM 484
Cdd:PRK07494  336 PDILSRTASVDLLNRSLLSDFLPVQDLRAAGLHLLYSFGPLRRLFM 381
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 58-487 7.89e-29

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 117.33  E-value: 7.89e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  58 DVIVSGGGMVGtaMACSLGFDPNlqGKKILLLEAgnkKEFEVPESYS-TRVSSISPGSATLLSGIGAWDHILNMRCKpfn 136
Cdd:PRK06617    3 NTVILGCGLSG--MLTALSFAQK--GIKTTIFES---KSVKSPEFFKdIRTTALTPHSKNFLFSIDIWEELEKFVAE--- 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 137 rMQ-VWDACSDAMITFDKENLEDE-MGYVVEND----VVMAALTKQ-LDAVSDQVKvqyrsravrytwplpYQTAESNPW 209
Cdd:PRK06617   73 -MQdIYVVDNKASEILDLRNDADAvLGYVVKNSdfkkILLSKITNNpLITLIDNNQ---------------YQEVISHND 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 210 VQVELASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHlsEPTENNVAWQRFLPTGPIALLPLSDS-AS 288
Cdd:PRK06617  137 YSIIKFDDKQIKCNLLIICDGANSKVRSHYFANEIEKPYQTALTFNIKH--EKPHENCAMEHFLPLGPFALLPLKDQyAS 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 289 SLVWSTTHQHATDLLALDDESFvdainsAFWSNENhselihtAGTvfrsalsllmpsgtsprqlppSVSRVGPKSK-AMF 367
Cdd:PRK06617  215 SVIWSTSSDQAALIVNLPVEEV------RFLTQRN-------AGN---------------------SLGKITIDSEiSSF 260

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 368 PLGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFdgrdlgatrhLLEYETERQRHNLPMMAA 447
Cdd:PRK06617  261 PLKARIANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDIEILSMIVSNNGT----------LQEYQKLRQEDNFIMYKL 330

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 2565188145 448 IDILKRLYSTKMAPFVLLRTLGLQATSAVPPLKEQIMAFA 487
Cdd:PRK06617  331 TDELNNIFSNYSKNLRCLRQIGFKVINNFKPIKNLITSYA 370
PRK06834 PRK06834
hypothetical protein; Provisional
 210-467 1.31e-10

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 63.50  E-value: 1.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 210 VQVELASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPTENNVawqRFLPTGPIALLPLSDSAS- 288
Cdd:PRK06834  133 VDVELSDGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEEPEWGV---HRDALGIHAFGRLEDEGPv 209

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 289 SLVWSTTHQHATDLLALDDESfvdainsafwsnenhSELIHTAGTVFrsalsllmpsGTSPrqlPPSVSRVGPKSKamfp 368
Cdd:PRK06834  210 RVMVTEKQVGATGEPTLDDLR---------------EALIAVYGTDY----------GIHS---PTWISRFTDMAR---- 257

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 369 lglgHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAfdgRDLGATRHLLEYETERQrhnlPMMAai 448
Cdd:PRK06834  258 ----QAASYRDGRVLLAGDAAHVHSPVGGQGLNTGVQDAVNLGWKLAQVV---KGTSPESLLDTYHAERH----PVAA-- 324

                         250
                  ....*....|....*....
gi 2565188145 449 dilkRLYSTKMAPFVLLRT 467
Cdd:PRK06834  325 ----RVLRNTMAQVALLRP 339
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 57-440 1.48e-09

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 59.65  E-value: 1.48e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  57 YDVIVSGGGMVGTAMACSLGfdpnLQGKKILLLEAGNKKefevpeSYSTRVSSISPGSATLLSGIGAWDHILNMrCKPFN 136
Cdd:pfam01494   2 TDVLIVGGGPAGLMLALLLA----RAGVRVVLVERHATT------SVLPRAHGLNQRTMELLRQAGLEDRILAE-GVPHE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 137 RMQVWDACSDAMItfdkeNLEDEMGYVVENDVVMAALTKQL--DAVSDQVKVQyrsRAVRYTWPLPYQTAESNPWVQVEL 214
Cdd:pfam01494  71 GMGLAFYNTRRRA-----DLDFLTSPPRVTVYPQTELEPILveHAEARGAQVR---FGTEVLSLEQDGDGVTAVVRDRRD 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 215 ASGQQLQTKLLIGADGPNSTVRKAAGMQ-----TVQWNyEQSAVVAVLHLSEPTENN--VAWQRFLPTGPIALLPlsdsa 287
Cdd:pfam01494 143 GEEYTVRAKYLVGCDGGRSPVRKTLGIEfegfeGVPFG-SLDVLFDAPDLSDPVERAfvHYLIYAPHSRGFMVGP----- 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 288 sslVWSTTHQHATDLLALDDESfvdainsAFWSNEnhselihtagtVFRSALSLLMPSGTSPRQLPPSVSRvgpksKAMF 367
Cdd:pfam01494 217 ---WRSAGRERYYVQVPWDEEV-------EERPEE-----------FTDEELKQRLRSIVGIDLALVEILW-----KSIW 270

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2565188145 368 PLGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSqAAFDGRdlgATRHLLE-YETERQRH 440
Cdd:pfam01494 271 GVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLA-AVLRGQ---AGESLLDtYSAERLPV 340
PRK07045 PRK07045
putative monooxygenase; Reviewed
 211-417 3.63e-08

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 55.30  E-value: 3.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 211 QVELASGQQLQTKLLIGADGPNSTVRK-AAGMQTVQWNYEQSAVVAVLHLSEPTENNVAWQRFLPTGPIALLPLSDSASS 289
Cdd:PRK07045  143 SVTLSDGERVAPTVLVGADGARSMIRDdVLRMPAERVPYATPMAFGTIALTDSVRECNRLYVDSNQGLAYFYPIGDQATR 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 290 LVWSTTHQHATDLLALDDESFVDAINSAFWSNENHSELIH-TAGTVFRsalsllmpsgtsprqlppsvsrvgpkskaMFP 368
Cdd:PRK07045  223 LVVSFPADEMQGYLADTTRTKLLARLNEFVGDESADAMAAiGAGTAFP-----------------------------LIP 273

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2565188145 369 LGLGHASEYIRHRVALIGDAAHRVHPLAGQGVNLGFGDV----ACLTRHLSQA 417
Cdd:PRK07045  274 LGRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAgelgACLDLHLSGQ 326
PRK08244 PRK08244
monooxygenase;
220-437 9.41e-08

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 54.36  E-value: 9.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 220 LQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVLHLSEPTENNVAwQRFLPTGPIALLPLSDSASSLVWSTTHQHA 299
Cdd:PRK08244  146 LTSSYVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDVVLKDPPPSSVL-SLCTREGGVMIVPLSGGIYRVLIIDPERPQ 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 300 TdllaLDDESFVDainsafwsNENHSELIHTAGTVFrsalsllmpsGTSPrqlPPSVSRVGPKSKamfplglgHASEYIR 379
Cdd:PRK08244  225 V----PKDEPVTL--------EELKTSLIRICGTDF----------GLND---PVWMSRFGNATR--------QAERYRS 271

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2565188145 380 HRVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSqAAFDGRdlgATRHLLE-YETER 437
Cdd:PRK08244  272 GRIFLAGDAAHIHFPAGGQGLNVGLQDAMNLGWKLA-AAIKGW---APDWLLDsYHAER 326
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
64-424 1.03e-07

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 53.43  E-value: 1.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  64 GGMVGTAMACSLGfdpnLQGKKILLLEagnKKEFevPEsYSTRVSSISPGSATLLSGIGAWDHILNmrckPFNRMQVWdA 143
Cdd:COG0644     1 AGPAGSAAARRLA----RAGLSVLLLE---KGSF--PG-DKICGGGLLPRALEELEPLGLDEPLER----PVRGARFY-S 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 144 CSDAMITFDKENledEMGYVVENDVVMAALTKQldAVSDQVKVQYRSRAVRYTWplpyqtaeSNPWVQVELASGQQLQTK 223
Cdd:COG0644    66 PGGKSVELPPGR---GGGYVVDRARFDRWLAEQ--AEEAGAEVRTGTRVTDVLR--------DDGRVVVRTGDGEEIRAD 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 224 LLIGADGPNSTVRKAAGMQTvqwnyeqsavvavlHLSEPTENNVAWQRFLPTGPIAllplsdsasslvwstthqhatdll 303
Cdd:COG0644   133 YVVDADGARSLLARKLGLKR--------------RSDEPQDYALAIKEHWELPPLE------------------------ 174

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 304 alddesfvdainsafwsNENHSELIHTAGTvfrsalslLMPSGTS---PrqLPPSVSRVGpkskamFPLGlGHASEYIRH 380
Cdd:COG0644   175 -----------------GVDPGAVEFFFGE--------GAPGGYGwvfP--LGDGRVSVG------IPLG-GPRPRLVGD 220

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 2565188145 381 RVALIGDAAHRVHPLAGQGVNLGF--GDVA--CLTRHLSQAAFDGRDL 424
Cdd:COG0644   221 GVLLVGDAAGFVDPLTGEGIHLAMksGRLAaeAIAEALEGGDFSAEAL 268
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
381-440 2.99e-05

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 46.44  E-value: 2.99e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2565188145 381 RVALIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSqAAFDGRdlgATRHLLE-YETERQRH 440
Cdd:PRK06183  287 RVLLAGDAAHLMPPFAGQGMNSGIRDAANLAWKLA-AVLRGR---AGDALLDtYEQERRPH 343
PRK06185 PRK06185
FAD-dependent oxidoreductase;
384-438 1.77e-04

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 43.69  E-value: 1.77e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2565188145 384 LIGDAAHRVHPLAGQGVNLGFGDVACLTRHLSQAAFDGRdlGATRHLLEYETERQ 438
Cdd:PRK06185  288 CIGDAAHAMSPVGGVGINLAIQDAVAAANILAEPLRRGR--VSDRDLAAVQRRRE 340
PRK06184 PRK06184
hypothetical protein; Provisional
 225-447 1.89e-04

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 43.82  E-value: 1.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 225 LIGADGPNSTVRKAAGM----QTVQwnyEQSAVVAVLHLS--EPTennvAWQRFLP--TGPIALLPLSDsasslvwstth 296
Cdd:PRK06184  160 LVGADGGRSFVRKALGIgfpgETLG---IDRMLVADVSLTglDRD----AWHQWPDgdMGMIALCPLPG----------- 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 297 qhaTDLLALddESFVDAINSAFWSNENHSELIHTAgtvfrsalsllmpSGTSPRQLppsvSRVGPKSKamFPLGLGHASE 376
Cdd:PRK06184  222 ---TDLFQI--QAPLPPGGEPDLSADGLTALLAER-------------TGRTDIRL----HSVTWASA--FRMNARLADR 277

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2565188145 377 YIRHRVALIGDAAHrVHPLAG-QGVNLGFGDVACLTRHLSQAAfdgrdLGATRHLLE-YETERqrhnLPMMAA 447
Cdd:PRK06184  278 YRVGRVFLAGDAAH-VHPPAGgQGLNTSVQDAYNLGWKLAAVL-----AGAPEALLDtYEEER----RPVAAA 340
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 53-416 4.25e-04

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 42.92  E-value: 4.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145  53 TDSVYDVIVSGGGMVGTAMACSLGfdpnLQGKKILLLEagnKKEFEVPEsystRVSS--ISPGSATLL---------SGI 121
Cdd:PTZ00367   30 TNYDYDVIIVGGSIAGPVLAKALS----KQGRKVLMLE---RDLFSKPD----RIVGelLQPGGVNALkelgmeecaEGI 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 122 GAWDH---ILNMRCKPFN---------------------RMQVWDACSDAMitfdkenledemgYVVENDVVmAALTKQL 177
Cdd:PTZ00367   99 GMPCFgyvVFDHKGKQVKlpygagasgvsfhfgdfvqnlRSHVFHNCQDNV-------------TMLEGTVN-SLLEEGP 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 178 DAVSDQVKVQYrSRAVRYTWPLPYQTAESNPWVQVELASGQQLQTKLLIGADGPNSTVRKAAGMQTVQWNYEQSAVVAVL 257
Cdd:PTZ00367  165 GFSERAYGVEY-TEAEKYDVPENPFREDPPSANPSATTVRKVATAPLVVMCDGGMSKFKSRYQHYTPASENHSHFVGLVL 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 258 ---HLSEPTENNVAwqrFLPTGPIALLPLSDSASSLVWSTTHQHATDLLALdDESFVDAINSAFWSNEnHSELIHTAgtv 334
Cdd:PTZ00367  244 knvRLPKEQHGTVF---LGKTGPILSYRLDDNELRVLVDYNKPTLPSLEEQ-SEWLIEDVAPHLPENM-RESFIRAS--- 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 335 fRSALSL-LMPSgtspRQLPPSvsrvgpkskamFPLGLGhaseyirhrVALIGDAAHRVHPLAGQGVNLGFGDVACLTRH 413
Cdd:PTZ00367  316 -KDTKRIrSMPN----ARYPPA-----------FPSIKG---------YVGIGDHANQRHPLTGGGMTCCFSDCIRLAKS 370


                  ...
gi 2565188145 414 LSQ 416
Cdd:PTZ00367  371 LTG 373
PRK07538 PRK07538
hypothetical protein; Provisional
 381-466 6.34e-04

hypothetical protein; Provisional


Pssm-ID: 236046 [Multi-domain]  Cd Length: 413  Bit Score: 42.19  E-value: 6.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2565188145 381 RVALIGDAAHRVHPLAGQGVnlgfgdvacltrhlSQAAFDGRDLG----ATRH----LLEYETERqrhnLPMMAAIDILK 452
Cdd:PRK07538  298 RVTLLGDAAHPMYPVGSNGA--------------SQAILDARALAdalaAHGDpeaaLAAYEAER----RPATAQIVLAN 359

                          90
                  ....*....|....
gi 2565188145 453 RLystkMAPFVLLR 466
Cdd:PRK07538  360 RL----NGPEGVLQ 369
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH