|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00191 |
PLN00191 |
enolase |
3-435 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 815.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 3 FSMSITKIHAREILDSRGNPTVEVDLYTAKGRFRAAVPSGASTGVHEALELRDGDKsRYLGKGTVKAVDHVNKDIAAKLI 82
Cdd:PLN00191 24 VMATITKVKARQIIDSRGNPTVEVDLHTSKGMFRAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 83 EKkfSVVDQEKIDQFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGHKDVILPCPAFNVINGGSH 162
Cdd:PLN00191 103 GM--DPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHIADLAGNKKLVLPVPAFNVINGGSH 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 163 AGNKLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKYGKDATNVGDEGGFAPNILENNEALELLKSAIEKAGYPD 242
Cdd:PLN00191 181 AGNKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKYGQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYTG 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 243 KIIIGMDVAASEFY-KAGKYDLDFKSPD-DPARYITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWSKFTAAVDIQVV 320
Cdd:PLN00191 261 KIKIGMDVAASEFYtKDKKYDLDFKEENnDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSLEDVQIV 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 321 GDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTG 400
Cdd:PLN00191 341 GDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQIKTG 420
|
410 420 430
....*....|....*....|....*....|....*
gi 1782257411 401 APCRSERLAKYNQLMRIEEELGNKAKFAGKDYRHP 435
Cdd:PLN00191 421 APCRSERLAKYNQLLRIEEELGDEAVYAGENFRKP 455
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
9-420 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 772.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 9 KIHAREILDSRGNPTVEVDLYTA-KGRFRAAVPSGASTGVHEALELRDGDKSRYLGKGTVKAVDHVNKDIAAKLIekKFS 87
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEdGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALI--GMD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 88 VVDQEKIDQFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGHkdvILPCPAFNVINGGSHAGNKL 167
Cdd:cd03313 79 VTDQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAY---VLPVPMFNVINGGAHAGNKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 168 AMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKYGKDATNVGDEGGFAPNILENNEALELLKSAIEKAGYPD--KII 245
Cdd:cd03313 156 DFQEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGGLLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPgkKIA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 246 IGMDVAASEFYKAGKYDLDfkspDDPARYITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWSKFTAAV--DIQVVGDD 323
Cdd:cd03313 236 IALDVAASEFYDEGKYVYD----SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLgdKIQIVGDD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 324 LTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPC 403
Cdd:cd03313 312 LFVTNPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPC 391
|
410
....*....|....*..
gi 1782257411 404 RSERLAKYNQLMRIEEE 420
Cdd:cd03313 392 RSERTAKYNQLLRIEEE 408
|
|
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
5-431 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 720.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 5 MS-ITKIHAREILDSRGNPTVEVDLYTAKGRF-RAAVPSGASTGVHEALELRDGDKSRYLGKGTVKAVDHVNKDIAAKLI 82
Cdd:COG0148 1 MSrIEDVHAREILDSRGNPTVEVEVTLEDGAVgRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 83 ekKFSVVDQEKIDQFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGHkdvILPCPAFNVINGGSH 162
Cdd:COG0148 81 --GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAK---TLPVPMMNIINGGAH 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 163 AGNKLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKygKDATNVGDEGGFAPNILENNEALELLKSAIEKAGY-P 241
Cdd:COG0148 156 ADNNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEK--GLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYkP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 242 -DKIIIGMDVAASEFYKAGKYDLDFKSpddpaRYITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWSKFTAAV--DIQ 318
Cdd:COG0148 234 gEDIALALDVAASEFYKDGKYHLKGEG-----KELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLgdKVQ 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 319 VVGDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIK 398
Cdd:COG0148 309 LVGDDLFVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIK 388
|
410 420 430
....*....|....*....|....*....|...
gi 1782257411 399 TGAPCRSERLAKYNQLMRIEEELGNKAKFAGKD 431
Cdd:COG0148 389 TGSPSRSERVAKYNQLLRIEEELGDAARYAGRS 421
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
7-435 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 605.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 7 ITKIHAREILDSRGNPTVEVDLYTAKGRF-RAAVPSGASTGVHEALELRDGDKSRYLGKGTVKAVDHVNKDIAAKLIekK 85
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFgRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELI--G 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 86 FSVVDQEKIDQFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHiadLAGHKDVILPCPAFNVINGGSHAGN 165
Cdd:TIGR01060 79 MDATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRY---LGGFNAYVLPVPMMNIINGGAHADN 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 166 KLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKYgkDATNVGDEGGFAPNILENNEALELLKSAIEKAGYP--DK 243
Cdd:TIGR01060 156 NLDFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKG--LATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKpgED 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 244 IIIGMDVAASEFY--KAGKYDLDFKSpddpaRYITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWSKFTAAV--DIQV 319
Cdd:TIGR01060 234 VALALDCAASEFYdeEDGKYVYKGEN-----KQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLgdKVQI 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 320 VGDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKT 399
Cdd:TIGR01060 309 VGDDLFVTNTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKT 388
|
410 420 430
....*....|....*....|....*....|....*.
gi 1782257411 400 GAPCRSERLAKYNQLMRIEEELGNKAKFAGKDYRHP 435
Cdd:TIGR01060 389 GSLSRSERIAKYNQLLRIEEELGDSARYAGKNSFYR 424
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
148-435 |
2.27e-179 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 502.39 E-value: 2.27e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 148 ILPCPAFNVINGGSHAGNKLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKYGKDATNVGDEGGFAPNILENNEA 227
Cdd:pfam00113 3 VLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGQSATNVGDEGGFAPNLQSNKEA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 228 LELLKSAIEKAGYPDKIIIGMDVAASEFYKA--GKYDLDFKSPD-DPARYITGDQLGDLYKSFIKGYPVQSIEDPFDQDD 304
Cdd:pfam00113 83 LDLIVEAIEKAGYKGKIKIAMDVASSEFYNKkdGKYDLDFKGEKsDKSKKLTSAQLADLYEELVKKYPIVSIEDPFDEDD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 305 WAAWSKFTAAVD--IQVVGDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETED 382
Cdd:pfam00113 163 WEAWKYLTERLGdkVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGETED 242
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1782257411 383 TFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGNKAKFAGKDYRHP 435
Cdd:pfam00113 243 TTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKP 295
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00191 |
PLN00191 |
enolase |
3-435 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 815.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 3 FSMSITKIHAREILDSRGNPTVEVDLYTAKGRFRAAVPSGASTGVHEALELRDGDKsRYLGKGTVKAVDHVNKDIAAKLI 82
Cdd:PLN00191 24 VMATITKVKARQIIDSRGNPTVEVDLHTSKGMFRAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 83 EKkfSVVDQEKIDQFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGHKDVILPCPAFNVINGGSH 162
Cdd:PLN00191 103 GM--DPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHIADLAGNKKLVLPVPAFNVINGGSH 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 163 AGNKLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKYGKDATNVGDEGGFAPNILENNEALELLKSAIEKAGYPD 242
Cdd:PLN00191 181 AGNKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKYGQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYTG 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 243 KIIIGMDVAASEFY-KAGKYDLDFKSPD-DPARYITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWSKFTAAVDIQVV 320
Cdd:PLN00191 261 KIKIGMDVAASEFYtKDKKYDLDFKEENnDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSLEDVQIV 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 321 GDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTG 400
Cdd:PLN00191 341 GDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQIKTG 420
|
410 420 430
....*....|....*....|....*....|....*
gi 1782257411 401 APCRSERLAKYNQLMRIEEELGNKAKFAGKDYRHP 435
Cdd:PLN00191 421 APCRSERLAKYNQLLRIEEELGDEAVYAGENFRKP 455
|
|
| PTZ00081 |
PTZ00081 |
enolase; Provisional |
5-430 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 240259 [Multi-domain] Cd Length: 439 Bit Score: 795.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 5 MSITKIHAREILDSRGNPTVEVDLYTAKGRFRAAVPSGASTGVHEALELRDGDKSRYLGKGTVKAVDHVNKDIAAKLIEK 84
Cdd:PTZ00081 2 STIKSIKAREILDSRGNPTVEVDLTTEKGVFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALIGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 85 kfSVVDQEKIDQFMLE-LDGTEN-----KSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAG--HKDVILPCPAFNV 156
Cdd:PTZ00081 82 --DVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGkpTDKFVLPVPCFNV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 157 INGGSHAGNKLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKYGKDATNVGDEGGFAPNILENNEALELLKSAIE 236
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKYGLDATNVGDEGGFAPNIKDPEEALDLLVEAIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 237 KAGYPDKIIIGMDVAASEFYKAGK--YDLDFKSPDDP-ARYITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWSKFTA 313
Cdd:PTZ00081 240 KAGYEGKVKICMDVAASEFYDKEKkvYDLDFKNPNNDkSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKLTA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 314 AV--DIQVVGDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVG 391
Cdd:PTZ00081 320 AIgqKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLVVG 399
|
410 420 430
....*....|....*....|....*....|....*....
gi 1782257411 392 LCTGQIKTGAPCRSERLAKYNQLMRIEEELGNKAKFAGK 430
Cdd:PTZ00081 400 LGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAGE 438
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
9-420 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 772.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 9 KIHAREILDSRGNPTVEVDLYTA-KGRFRAAVPSGASTGVHEALELRDGDKSRYLGKGTVKAVDHVNKDIAAKLIekKFS 87
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEdGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALI--GMD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 88 VVDQEKIDQFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGHkdvILPCPAFNVINGGSHAGNKL 167
Cdd:cd03313 79 VTDQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAY---VLPVPMFNVINGGAHAGNKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 168 AMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKYGKDATNVGDEGGFAPNILENNEALELLKSAIEKAGYPD--KII 245
Cdd:cd03313 156 DFQEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGGLLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPgkKIA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 246 IGMDVAASEFYKAGKYDLDfkspDDPARYITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWSKFTAAV--DIQVVGDD 323
Cdd:cd03313 236 IALDVAASEFYDEGKYVYD----SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLgdKIQIVGDD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 324 LTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPC 403
Cdd:cd03313 312 LFVTNPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPC 391
|
410
....*....|....*..
gi 1782257411 404 RSERLAKYNQLMRIEEE 420
Cdd:cd03313 392 RSERTAKYNQLLRIEEE 408
|
|
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
5-431 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 720.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 5 MS-ITKIHAREILDSRGNPTVEVDLYTAKGRF-RAAVPSGASTGVHEALELRDGDKSRYLGKGTVKAVDHVNKDIAAKLI 82
Cdd:COG0148 1 MSrIEDVHAREILDSRGNPTVEVEVTLEDGAVgRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 83 ekKFSVVDQEKIDQFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGHkdvILPCPAFNVINGGSH 162
Cdd:COG0148 81 --GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAK---TLPVPMMNIINGGAH 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 163 AGNKLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKygKDATNVGDEGGFAPNILENNEALELLKSAIEKAGY-P 241
Cdd:COG0148 156 ADNNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEK--GLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYkP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 242 -DKIIIGMDVAASEFYKAGKYDLDFKSpddpaRYITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWSKFTAAV--DIQ 318
Cdd:COG0148 234 gEDIALALDVAASEFYKDGKYHLKGEG-----KELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLgdKVQ 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 319 VVGDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIK 398
Cdd:COG0148 309 LVGDDLFVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIK 388
|
410 420 430
....*....|....*....|....*....|...
gi 1782257411 399 TGAPCRSERLAKYNQLMRIEEELGNKAKFAGKD 431
Cdd:COG0148 389 TGSPSRSERVAKYNQLLRIEEELGDAARYAGRS 421
|
|
| eno |
PRK00077 |
enolase; Provisional |
5-431 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 692.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 5 MSITKIHAREILDSRGNPTVEVDLYTAKGRF-RAAVPSGASTGVHEALELRDGDKSRYLGKGTVKAVDHVNKDIAAKLIE 83
Cdd:PRK00077 2 SKIEDIIAREILDSRGNPTVEVEVTLEDGAFgRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 84 kkFSVVDQEKIDQFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGHkdvILPCPAFNVINGGSHA 163
Cdd:PRK00077 82 --LDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAK---VLPVPMMNIINGGAHA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 164 GNKLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKyGKdATNVGDEGGFAPNILENNEALELLKSAIEKAGY-PD 242
Cdd:PRK00077 157 DNNVDIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEK-GL-STAVGDEGGFAPNLKSNEEALDLILEAIEKAGYkPG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 243 KII-IGMDVAASEFYKAGKYDLDFKSpddparyITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWSKFTAAV--DIQV 319
Cdd:PRK00077 235 EDIaLALDCAASEFYKDGKYVLEGEG-------LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLgdKVQL 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 320 VGDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKT 399
Cdd:PRK00077 308 VGDDLFVTNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKT 387
|
410 420 430
....*....|....*....|....*....|..
gi 1782257411 400 GAPCRSERLAKYNQLMRIEEELGNKAKFAGKD 431
Cdd:PRK00077 388 GSLSRSERIAKYNQLLRIEEELGDAARYAGKK 419
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
7-435 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 605.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 7 ITKIHAREILDSRGNPTVEVDLYTAKGRF-RAAVPSGASTGVHEALELRDGDKSRYLGKGTVKAVDHVNKDIAAKLIekK 85
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFgRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELI--G 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 86 FSVVDQEKIDQFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHiadLAGHKDVILPCPAFNVINGGSHAGN 165
Cdd:TIGR01060 79 MDATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRY---LGGFNAYVLPVPMMNIINGGAHADN 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 166 KLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKYgkDATNVGDEGGFAPNILENNEALELLKSAIEKAGYP--DK 243
Cdd:TIGR01060 156 NLDFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKG--LATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKpgED 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 244 IIIGMDVAASEFY--KAGKYDLDFKSpddpaRYITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWSKFTAAV--DIQV 319
Cdd:TIGR01060 234 VALALDCAASEFYdeEDGKYVYKGEN-----KQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLgdKVQI 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 320 VGDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKT 399
Cdd:TIGR01060 309 VGDDLFVTNTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKT 388
|
410 420 430
....*....|....*....|....*....|....*.
gi 1782257411 400 GAPCRSERLAKYNQLMRIEEELGNKAKFAGKDYRHP 435
Cdd:TIGR01060 389 GSLSRSERIAKYNQLLRIEEELGDSARYAGKNSFYR 424
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
148-435 |
2.27e-179 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 502.39 E-value: 2.27e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 148 ILPCPAFNVINGGSHAGNKLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKYGKDATNVGDEGGFAPNILENNEA 227
Cdd:pfam00113 3 VLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGQSATNVGDEGGFAPNLQSNKEA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 228 LELLKSAIEKAGYPDKIIIGMDVAASEFYKA--GKYDLDFKSPD-DPARYITGDQLGDLYKSFIKGYPVQSIEDPFDQDD 304
Cdd:pfam00113 83 LDLIVEAIEKAGYKGKIKIAMDVASSEFYNKkdGKYDLDFKGEKsDKSKKLTSAQLADLYEELVKKYPIVSIEDPFDEDD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 305 WAAWSKFTAAVD--IQVVGDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETED 382
Cdd:pfam00113 163 WEAWKYLTERLGdkVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGETED 242
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1782257411 383 TFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGNKAKFAGKDYRHP 435
Cdd:pfam00113 243 TTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKP 295
|
|
| Enolase_N |
pfam03952 |
Enolase, N-terminal domain; |
7-138 |
2.03e-84 |
|
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain] Cd Length: 131 Bit Score: 254.61 E-value: 2.03e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 7 ITKIHAREILDSRGNPTVEVDLYTAKGRF-RAAVPSGASTGVHEALELRDGDKSRYLGKGTVKAVDHVNKDIAAKLIekK 85
Cdd:pfam03952 1 ITKVKAREILDSRGNPTVEVEVTLEDGTFgRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALI--G 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1782257411 86 FSVVDQEKIDQFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHI 138
Cdd:pfam03952 79 MDATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
|
|
| enolase_like |
cd00308 |
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ... |
270-392 |
3.68e-20 |
|
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.
Pssm-ID: 238188 [Multi-domain] Cd Length: 229 Bit Score: 88.92 E-value: 3.68e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 270 DPARYITGDQLGDLYKSfIKGYPVQSIEDPFDQDDWAAWSKFTAAVDIQVVGDDLTVTNPKRIqQAVEKKACNCLLLKVN 349
Cdd:cd00308 100 DANGAWTPKEAIRLIRA-LEKYGLAWIEEPCAPDDLEGYAALRRRTGIPIAADESVTTVDDAL-EALELGAVDILQIKPT 177
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1782257411 350 QIGSVTESIKACKLAQSNGWGVMVSHRSG-ETEDTFIADLVVGL 392
Cdd:cd00308 178 RVGGLTESRRAADLAEAFGIRVMVHGTLEsSIGTAAALHLAAAL 221
|
|
| PRK08350 |
PRK08350 |
hypothetical protein; Provisional |
20-138 |
7.21e-14 |
|
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain] Cd Length: 341 Bit Score: 72.53 E-value: 7.21e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 20 GNPTVEVDLYTAKGRFRAAVPSgastgvhealelrDGDKSRYLGKGTvKAVDHVNKDIAAKLIekKFSVVDQEKIDQFML 99
Cdd:PRK08350 17 GKYSVEVDVITDSGFGRFAAPI-------------DENPSLYIAEAH-RAVSEVDEIIGPELI--GFDASEQELIDSYLW 80
|
90 100 110
....*....|....*....|....*....|....*....
gi 1782257411 100 ELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHI 138
Cdd:PRK08350 81 EIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYI 119
|
|
| RspA |
COG4948 |
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ... |
288-373 |
2.97e-08 |
|
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 443975 [Multi-domain] Cd Length: 359 Bit Score: 55.21 E-value: 2.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 288 IKGYPVQSIEDPFDQDDWAAWSKFTAAVDIQVVGDDlTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSN 367
Cdd:COG4948 205 LEDLGLEWIEQPLPAEDLEGLAELRRATPVPIAADE-SLTSRADFRRLIEAGAVDIVNIKLSKVGGLTEALRIAALAEAH 283
|
....*.
gi 1782257411 368 GWGVMV 373
Cdd:COG4948 284 GVPVMP 289
|
|
| MLE_like |
cd03315 |
Muconate lactonizing enzyme (MLE) like subgroup of the enolase superfamily. Enzymes of this ... |
296-374 |
6.99e-04 |
|
Muconate lactonizing enzyme (MLE) like subgroup of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and residues that can function as general acid/base catalysts, a Lys-X-Lys motif and another conserved lysine. Despite these conserved residues, the members of the MLE subgroup, like muconate lactonizing enzyme, o-succinylbenzoate synthase (OSBS) and N-acylamino acid racemase (NAAAR), catalyze different reactions.
Pssm-ID: 239431 [Multi-domain] Cd Length: 265 Bit Score: 41.17 E-value: 6.99e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1782257411 296 IEDPFDQDDWAAWSKFTAAVDIQVVGDDlTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVS 374
Cdd:cd03315 160 VEQPLPADDLEGRAALARATDTPIMADE-SAFTPHDAFRELALGAADAVNIKTAKTGGLTKAQRVLAVAEALGLPVMVG 237
|
|
| L-Ala-DL-Glu_epimerase |
cd03319 |
L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The ... |
291-373 |
4.78e-03 |
|
L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of the murein peptide of peptidoglycan, of which L-Ala-D-Glu is a component. L-Ala-D/L-Glu epimerase is a member of the enolase-superfamily, which is characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239435 [Multi-domain] Cd Length: 316 Bit Score: 38.71 E-value: 4.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 291 YPVQSIEDPFDQDDWAAWSKFTAAVDIQVVGDDlTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWG 370
Cdd:cd03319 203 LGVELIEQPVPAGDDDGLAYLRDKSPLPIMADE-SCFSAADAARLAGGGAYDGINIKLMKTGGLTEALRIADLARAAGLK 281
|
...
gi 1782257411 371 VMV 373
Cdd:cd03319 282 VMV 284
|
|
| MAL |
cd03314 |
Methylaspartate ammonia lyase (3-methylaspartase, MAL) is a homodimeric enzyme, catalyzing the ... |
289-395 |
4.91e-03 |
|
Methylaspartate ammonia lyase (3-methylaspartase, MAL) is a homodimeric enzyme, catalyzing the magnesium-dependent reversible alpha,beta-elimination of ammonia from L-threo-(2S,3S)-3-methylaspartic acid to mesaconic acid. This reaction is part of the main catabolic pathway for glutamate. MAL belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239430 [Multi-domain] Cd Length: 369 Bit Score: 38.92 E-value: 4.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782257411 289 KGYPVQsIEDPFD----QDDWAAWSKFTAA-----VDIQVVGDDLTVTnPKRIQQAVEKKACNCLLLKVNQIGSVTESIK 359
Cdd:cd03314 226 APFPLR-IEGPMDagsrEAQIERMAALRAEldrrgVGVRIVADEWCNT-LEDIRDFADAGAAHMVQIKTPDLGGIDNTID 303
|
90 100 110
....*....|....*....|....*....|....*.
gi 1782257411 360 ACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTG 395
Cdd:cd03314 304 AVLYCKEHGVGAYLGGSCNETDISARVTVHVALATR 339
|
|
| mandelate_racemase |
cd03321 |
Mandelate racemase (MR) catalyzes the Mg2+-dependent 1,1-proton transfer reaction that ... |
296-368 |
5.54e-03 |
|
Mandelate racemase (MR) catalyzes the Mg2+-dependent 1,1-proton transfer reaction that interconverts the enantiomers of mandelic acid. MR is the first enzyme in the bacterial pathway that converts mandelic acid to benzoic acid and allows this pathway to utilize either enantiomer of mandelate. MR belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239437 [Multi-domain] Cd Length: 355 Bit Score: 38.62 E-value: 5.54e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1782257411 296 IEDPFDQDDWAAWSKFTAAVDIQV-VGDDLTvtNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNG 368
Cdd:cd03321 217 IEEPTLQHDYEGHARIASALRTPVqMGENWL--GPEEMFKALSAGACDLVMPDLMKIGGVTGWLRASALAEQAG 288
|
|
| NAAAR |
cd03317 |
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of ... |
296-371 |
7.84e-03 |
|
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building blocks for antibiotics, herbicides, and drugs. NAAAR is a member of the enolase superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239433 [Multi-domain] Cd Length: 354 Bit Score: 38.37 E-value: 7.84e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1782257411 296 IEDPFDQDDWAAWSKFTAAVDIQVVGDDlTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGV 371
Cdd:cd03317 208 IEQPLAADDLIDHAELQKLLKTPICLDE-SIQSAEDARKAIELGACKIINIKPGRVGGLTEALKIHDLCQEHGIPV 282
|
|
| |
