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Conserved domains on  [gi|1768482563|ref|XP_031260675|]
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N-terminal acetyltransferase A complex auxiliary subunit NAA15 [Pistacia vera]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11420860)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NatA_aux_su pfam12569
N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal ...
 187-696 0e+00

N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal acetyltransferase A (NatA) auxiliary subunit (also known as NMDA receptor-regulated protein 1), which is a non-catalytic component of the NatA N-terminal acetyltransferase that catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-terminal acetylation plays a role in normal eukaryotic translation and processing, protecting against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome, and may present the N terminus of nascent polypeptides for acetylation.


:

Pssm-ID: 463630 [Multi-domain]  Cd Length: 514  Bit Score: 663.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 187 EHGEMLLYKISLLEECGSLKRALEELHKKELKIVDKLAYKEQEVSLLVKLGLLEEAAKLYRVLLSMNPDNYKYYEGLQKC 266
Cdd:pfam12569   2 EHSELLLYKNQIIAESGDLEEALEHLEKVEKQIVDKLAVLETKADYLLKLGRKEEAEATYRALLERNPENHAYYEGLEKA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 267 VGlysengnYSSDEIDQLDSLYESLGQQYTWSSAVKRIPLDFLQGDKFREAAFNYIRPLLTKGVPSLFSDLSPLYGQPGK 346
Cdd:pfam12569  82 LG-------ISKEDHEALLALYDELAEKYPRSDAPRRLPLDFLEGEEFKELADKYLRRMLRKGVPSLFVNLKSLYTDSEK 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 347 ADILEHLILELEHSIRTTGRCPGRE----EKEPPSTLMWTLFFLAQHYDRRGQYDVALSKIDEAIEHTPTVIDLYSVKSR 422
Cdd:pfam12569 155 VDIIEELVEGYVSSLKTNGKFSGSDngdgEKEPPSTLLWTYYFLAQHYDYLGSYEKALEYIDKAIDHTPTLIELYMTKAR 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 423 ILKHAGDLAAAAALADEARCMDLADRYVNSECVKRMLQADQVALAEKTAVLFTKDG-DQHNNLHDMQCMWYELASGESYF 501
Cdd:pfam12569 235 IYKHAGDLQKAAEWMDEARSLDLADRYINSKCAKYMLRANEVEEAEETCSKFTRNGvGALGNLNEMQCMWFLTEDGEAYQ 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 502 RQCDLGRSLKKFLAVEKHYADITEDQFDFHSYCLRKMTLRAYVEMLKFQDRLHSHAYFHKAAVGAIRCYIKLYDSPPKST 581
Cdd:pfam12569 315 RQGKYGLALKRFHAVEKHFDEWEEDQFDFHTYCLRKMTLRAYVDMLRWEDRLRSHPFYFKAAKGAIEVYLRLHDKPLLKE 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 582 NEEDDDK-ANLLPSQKKKLKQKQRKAEARAKKEAEIKNEESSSSGVSKSGKRH---VKPVDPDPHGEKLLQVEDPLLEAT 657
Cdd:pfam12569 395 GPEEEGDnGNLSPAERKKARKKQKKAEKKAEKEEAEKAAKKKKKKAEKKAKGEdgeTKKEDPDPLGEKLAQTEDPLEEAM 474

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 1768482563 658 KYLKLLLKNSPDSLETHLLSFEVNIRKQKILLAFQAVKQ 696
Cdd:pfam12569 475 KFLKPLLKLAPDNIETHLLAFEVYIRKKKYLLALQCLKA 513
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
20-246 1.16e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 1.16e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  20 YETKQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRSDREYREAIKC 99
Cdd:COG0457    19 RRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALED 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 100 YRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSKAVEILEAYEGTLEDDY 179
Cdd:COG0457    99 YDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAAL 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1768482563 180 PPDNERCEHGEMLLYKISLLEECGSLKRALEELHKKELKIVDKLAYKEQEVSLLVKLGLLEEAAKLY 246
Cdd:COG0457   179 LAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
 
Name Accession Description Interval E-value
NatA_aux_su pfam12569
N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal ...
 187-696 0e+00

N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal acetyltransferase A (NatA) auxiliary subunit (also known as NMDA receptor-regulated protein 1), which is a non-catalytic component of the NatA N-terminal acetyltransferase that catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-terminal acetylation plays a role in normal eukaryotic translation and processing, protecting against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome, and may present the N terminus of nascent polypeptides for acetylation.


Pssm-ID: 463630 [Multi-domain]  Cd Length: 514  Bit Score: 663.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 187 EHGEMLLYKISLLEECGSLKRALEELHKKELKIVDKLAYKEQEVSLLVKLGLLEEAAKLYRVLLSMNPDNYKYYEGLQKC 266
Cdd:pfam12569   2 EHSELLLYKNQIIAESGDLEEALEHLEKVEKQIVDKLAVLETKADYLLKLGRKEEAEATYRALLERNPENHAYYEGLEKA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 267 VGlysengnYSSDEIDQLDSLYESLGQQYTWSSAVKRIPLDFLQGDKFREAAFNYIRPLLTKGVPSLFSDLSPLYGQPGK 346
Cdd:pfam12569  82 LG-------ISKEDHEALLALYDELAEKYPRSDAPRRLPLDFLEGEEFKELADKYLRRMLRKGVPSLFVNLKSLYTDSEK 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 347 ADILEHLILELEHSIRTTGRCPGRE----EKEPPSTLMWTLFFLAQHYDRRGQYDVALSKIDEAIEHTPTVIDLYSVKSR 422
Cdd:pfam12569 155 VDIIEELVEGYVSSLKTNGKFSGSDngdgEKEPPSTLLWTYYFLAQHYDYLGSYEKALEYIDKAIDHTPTLIELYMTKAR 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 423 ILKHAGDLAAAAALADEARCMDLADRYVNSECVKRMLQADQVALAEKTAVLFTKDG-DQHNNLHDMQCMWYELASGESYF 501
Cdd:pfam12569 235 IYKHAGDLQKAAEWMDEARSLDLADRYINSKCAKYMLRANEVEEAEETCSKFTRNGvGALGNLNEMQCMWFLTEDGEAYQ 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 502 RQCDLGRSLKKFLAVEKHYADITEDQFDFHSYCLRKMTLRAYVEMLKFQDRLHSHAYFHKAAVGAIRCYIKLYDSPPKST 581
Cdd:pfam12569 315 RQGKYGLALKRFHAVEKHFDEWEEDQFDFHTYCLRKMTLRAYVDMLRWEDRLRSHPFYFKAAKGAIEVYLRLHDKPLLKE 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 582 NEEDDDK-ANLLPSQKKKLKQKQRKAEARAKKEAEIKNEESSSSGVSKSGKRH---VKPVDPDPHGEKLLQVEDPLLEAT 657
Cdd:pfam12569 395 GPEEEGDnGNLSPAERKKARKKQKKAEKKAEKEEAEKAAKKKKKKAEKKAKGEdgeTKKEDPDPLGEKLAQTEDPLEEAM 474

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 1768482563 658 KYLKLLLKNSPDSLETHLLSFEVNIRKQKILLAFQAVKQ 696
Cdd:pfam12569 475 KFLKPLLKLAPDNIETHLLAFEVYIRKKKYLLALQCLKA 513
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
20-246 1.16e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 1.16e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  20 YETKQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRSDREYREAIKC 99
Cdd:COG0457    19 RRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALED 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 100 YRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSKAVEILEAYEGTLEDDY 179
Cdd:COG0457    99 YDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAAL 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1768482563 180 PPDNERCEHGEMLLYKISLLEECGSLKRALEELHKKELKIVDKLAYKEQEVSLLVKLGLLEEAAKLY 246
Cdd:COG0457   179 LAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
TPR_11 pfam13414
TPR repeat;
84-124 1.60e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 42.46  E-value: 1.60e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1768482563  84 GLLYRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQM 124
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 3-256 2.60e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 2.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563   3 ASLPPKEANLFKLIVKSYET-KQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWH 81
Cdd:TIGR02917 628 LALQPDSALALLLLADAYAVmKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFE 707

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  82 VYGLLYRSDREYREAIKCYRNALRIDPDNiEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNH---RMNWIGFAVAHHLN 158
Cdd:TIGR02917 708 LEGDLYLRQKDYPAAIQAYRKALKRAPSS-QNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDavlRTALAELYLAQKDY 786

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 159 SNGSKAVEILeayegtleDDYPPDNercehgEMLLYKISLLEECGSLKRALeELHKKELK-------IVDKLAYkeqevs 231
Cdd:TIGR02917 787 DKAIKHYQTV--------VKKAPDN------AVVLNNLAWLYLELKDPRAL-EYAERALKlapnipaILDTLGW------ 845

                         250       260
                  ....*....|....*....|....*
gi 1768482563 232 LLVKLGLLEEAAKLYRVLLSMNPDN 256
Cdd:TIGR02917 846 LLVEKGEADRALPLLRKAVNIAPEA 870
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 84-110 1.66e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.66e-03
                           10        20
                   ....*....|....*....|....*..
gi 1768482563   84 GLLYRSDREYREAIKCYRNALRIDPDN 110
Cdd:smart00028   8 GNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
NatA_aux_su pfam12569
N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal ...
 187-696 0e+00

N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal acetyltransferase A (NatA) auxiliary subunit (also known as NMDA receptor-regulated protein 1), which is a non-catalytic component of the NatA N-terminal acetyltransferase that catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-terminal acetylation plays a role in normal eukaryotic translation and processing, protecting against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome, and may present the N terminus of nascent polypeptides for acetylation.


Pssm-ID: 463630 [Multi-domain]  Cd Length: 514  Bit Score: 663.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 187 EHGEMLLYKISLLEECGSLKRALEELHKKELKIVDKLAYKEQEVSLLVKLGLLEEAAKLYRVLLSMNPDNYKYYEGLQKC 266
Cdd:pfam12569   2 EHSELLLYKNQIIAESGDLEEALEHLEKVEKQIVDKLAVLETKADYLLKLGRKEEAEATYRALLERNPENHAYYEGLEKA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 267 VGlysengnYSSDEIDQLDSLYESLGQQYTWSSAVKRIPLDFLQGDKFREAAFNYIRPLLTKGVPSLFSDLSPLYGQPGK 346
Cdd:pfam12569  82 LG-------ISKEDHEALLALYDELAEKYPRSDAPRRLPLDFLEGEEFKELADKYLRRMLRKGVPSLFVNLKSLYTDSEK 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 347 ADILEHLILELEHSIRTTGRCPGRE----EKEPPSTLMWTLFFLAQHYDRRGQYDVALSKIDEAIEHTPTVIDLYSVKSR 422
Cdd:pfam12569 155 VDIIEELVEGYVSSLKTNGKFSGSDngdgEKEPPSTLLWTYYFLAQHYDYLGSYEKALEYIDKAIDHTPTLIELYMTKAR 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 423 ILKHAGDLAAAAALADEARCMDLADRYVNSECVKRMLQADQVALAEKTAVLFTKDG-DQHNNLHDMQCMWYELASGESYF 501
Cdd:pfam12569 235 IYKHAGDLQKAAEWMDEARSLDLADRYINSKCAKYMLRANEVEEAEETCSKFTRNGvGALGNLNEMQCMWFLTEDGEAYQ 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 502 RQCDLGRSLKKFLAVEKHYADITEDQFDFHSYCLRKMTLRAYVEMLKFQDRLHSHAYFHKAAVGAIRCYIKLYDSPPKST 581
Cdd:pfam12569 315 RQGKYGLALKRFHAVEKHFDEWEEDQFDFHTYCLRKMTLRAYVDMLRWEDRLRSHPFYFKAAKGAIEVYLRLHDKPLLKE 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 582 NEEDDDK-ANLLPSQKKKLKQKQRKAEARAKKEAEIKNEESSSSGVSKSGKRH---VKPVDPDPHGEKLLQVEDPLLEAT 657
Cdd:pfam12569 395 GPEEEGDnGNLSPAERKKARKKQKKAEKKAEKEEAEKAAKKKKKKAEKKAKGEdgeTKKEDPDPLGEKLAQTEDPLEEAM 474

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 1768482563 658 KYLKLLLKNSPDSLETHLLSFEVNIRKQKILLAFQAVKQ 696
Cdd:pfam12569 475 KFLKPLLKLAPDNIETHLLAFEVYIRKKKYLLALQCLKA 513
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
20-246 1.16e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 1.16e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  20 YETKQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRSDREYREAIKC 99
Cdd:COG0457    19 RRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALED 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 100 YRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSKAVEILEAYEGTLEDDY 179
Cdd:COG0457    99 YDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAAL 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1768482563 180 PPDNERCEHGEMLLYKISLLEECGSLKRALEELHKKELKIVDKLAYKEQEVSLLVKLGLLEEAAKLY 246
Cdd:COG0457   179 LAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 10-178 3.61e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 70.02  E-value: 3.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  10 ANLFKLIVKSYETKQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRS 89
Cdd:COG3914    79 ALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRR 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  90 DREYREAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMnWIGFAVAHHLNSNGSKAVEILE 169
Cdd:COG3914   159 LGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNAD-AHSNLLFALRQACDWEVYDRFE 237


                  ....*....
gi 1768482563 170 AYEGTLEDD 178
Cdd:COG3914   238 ELLAALARG 246
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
40-264 5.12e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 66.95  E-value: 5.12e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  40 PDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRSDREYREAIKCYRNALRIDPDNIEILRDLSL 119
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 120 LQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSKAveiLEAYEGTLEDDypPDnerceHGEMLLYKISLL 199
Cdd:COG0457    85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEA---IEAYERALELD--PD-----DADALYNLGIAL 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1768482563 200 EECGSLKRALEELHKKELKIVDKLAYKEQEVSLLVKLGLLEEAAKLYRVLLSMNPDNYKYYEGLQ 264
Cdd:COG0457   155 EKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAAL 219
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 20-144 4.78e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 61.36  E-value: 4.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  20 YETKQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRSDREYREAIKC 99
Cdd:COG4783    15 LLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALAL 94

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1768482563 100 YRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNH 144
Cdd:COG4783    95 LEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 80-185 5.04e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.09  E-value: 5.04e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  80 WHVYGLLYRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNS 159
Cdd:COG4235    20 WLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQG 99

                          90       100
                  ....*....|....*....|....*.
gi 1768482563 160 NGSKAVEILEAyegtLEDDYPPDNER 185
Cdd:COG4235   100 DYAEAIAAWQK----LLALLPADAPA 121
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 80-276 6.79e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 6.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  80 WHVYGLLYRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNS 159
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 160 NGSKAVEILEAYEGTLEDDYppdnercehgEMLLYKISLLEECGSLKRALEELhKKELKIVDKLAYKEQEVS-LLVKLGL 238
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDA----------EALRLLAEIYEQEGDWEKAIEVL-ERLLKLGPENAHAYCELAeLYLEQGD 159

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1768482563 239 LEEAAKLYRVLLSMNPDNYKYYEGLQKcvgLYSENGNY 276
Cdd:COG2956   160 YDEAIEALEKALKLDPDCARALLLLAE---LYLEQGDY 194
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
73-247 9.81e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.94  E-value: 9.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  73 DIKSHVCWHVYGLLYRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFA 152
Cdd:COG0457     4 DPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 153 VAHHLNSNGSKAveiLEAYEGTLEDDypPDNercehGEMLLYKISLLEECGSLKRALEELHK-KELKIVDKLAYKEQEVs 231
Cdd:COG0457    84 LALQALGRYEEA---LEDYDKALELD--PDD-----AEALYNLGLALLELGRYDEAIEAYERaLELDPDDADALYNLGI- 152

                         170
                  ....*....|....*.
gi 1768482563 232 LLVKLGLLEEAAKLYR 247
Cdd:COG0457   153 ALEKLGRYEEALELLE 168
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 10-253 2.22e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.28  E-value: 2.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  10 ANLFklivksYETKQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRS 89
Cdd:COG2956    49 GNLY------RRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQ 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  90 DREYREAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSKAveiLE 169
Cdd:COG2956   123 EGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEA---IA 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 170 AYEGTLEDDYppdnercEHGEMLLYKISLLEECGSLKRALEELhKKELKIVDKLAYKEQEVSLLVKLGLLEEAAKLYRVL 249
Cdd:COG2956   200 ALERALEQDP-------DYLPALPRLAELYEKLGDPEEALELL-RKALELDPSDDLLLALADLLERKEGLEAALALLERQ 271


                  ....
gi 1768482563 250 LSMN 253
Cdd:COG2956   272 LRRH 275
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 84-260 4.64e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.93  E-value: 4.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  84 GLLYRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSK 163
Cdd:COG3914    85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 164 AVEILEayegtleddyppdnercehgemllykislleecgslkRALEeLHKKELKIVDKLAykeqevSLLVKLGLLEEAA 243
Cdd:COG3914   165 AIAALR-------------------------------------RALE-LDPDNAEALNNLG------NALQDLGRLEEAI 200

                         170
                  ....*....|....*..
gi 1768482563 244 KLYRVLLSMNPDNYKYY 260
Cdd:COG3914   201 AAYRRALELDPDNADAH 217
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 6-182 1.65e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.00  E-value: 1.65e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563   6 PPKEANLFKLIVKSYETKQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGL 85
Cdd:COG3914   109 PDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGN 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  86 LYRSDREYREAIKCYRNALRIDPDNIEILrdLSLLQAQMRDLA-GFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSKA 164
Cdd:COG3914   189 ALQDLGRLEEAIAAYRRALELDPDNADAH--SNLLFALRQACDwEVYDRFEELLAALARGPSELSPFALLYLPDDDPAEL 266

                         170
                  ....*....|....*...
gi 1768482563 165 VEILEAYEGTLEDDYPPD 182
Cdd:COG3914   267 LALARAWAQLVAAAAAPE 284
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 44-171 2.08e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.96  E-value: 2.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  44 ETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQ 123
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1768482563 124 MRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSKAVEILEAY 171
Cdd:COG4783    85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKA 132
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 29-142 4.51e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 50.34  E-value: 4.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  29 LKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRSDREYREAIKCYRNALRIDP 108
Cdd:COG5010    40 DELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSP 119

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1768482563 109 DNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKP 142
Cdd:COG5010   120 DNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 83-170 6.12e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.96  E-value: 6.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  83 YGLLYRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGS 162
Cdd:COG5010    60 SDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDD 139


                  ....*...
gi 1768482563 163 KAVEILEA 170
Cdd:COG5010   140 EAKAALQR 147
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 31-171 2.15e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.53  E-value: 2.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  31 AADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRSDREYREAIKCYRNALRIDPDN 110
Cdd:COG3914    66 EAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDF 145

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1768482563 111 IEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSKAVEILEAY 171
Cdd:COG3914   146 AEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRA 206
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
86-171 9.96e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.78  E-value: 9.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  86 LYRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRqQLLTLKPNHRMNWIGFAVAHHLNSNGSKAV 165
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALE-KALKLDPNNAEALLNLAELLLELGDYDEAL 79


                  ....*.
gi 1768482563 166 EILEAY 171
Cdd:COG3063    80 AYLERA 85
TPR_11 pfam13414
TPR repeat;
84-124 1.60e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 42.46  E-value: 1.60e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1768482563  84 GLLYRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQM 124
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
84-185 1.91e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.83  E-value: 1.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  84 GLLYRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSK 163
Cdd:COG4785    80 GVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYEL 159

                          90       100
                  ....*....|....*....|..
gi 1768482563 164 AVEILEAYegtLEDDyPPDNER 185
Cdd:COG4785   160 AIADLEKA---LELD-PNDPER 177
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 3-256 2.60e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 2.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563   3 ASLPPKEANLFKLIVKSYET-KQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWH 81
Cdd:TIGR02917 628 LALQPDSALALLLLADAYAVmKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFE 707

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  82 VYGLLYRSDREYREAIKCYRNALRIDPDNiEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNH---RMNWIGFAVAHHLN 158
Cdd:TIGR02917 708 LEGDLYLRQKDYPAAIQAYRKALKRAPSS-QNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDavlRTALAELYLAQKDY 786

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 159 SNGSKAVEILeayegtleDDYPPDNercehgEMLLYKISLLEECGSLKRALeELHKKELK-------IVDKLAYkeqevs 231
Cdd:TIGR02917 787 DKAIKHYQTV--------VKKAPDN------AVVLNNLAWLYLELKDPRAL-EYAERALKlapnipaILDTLGW------ 845

                         250       260
                  ....*....|....*....|....*
gi 1768482563 232 LLVKLGLLEEAAKLYRVLLSMNPDN 256
Cdd:TIGR02917 846 LLVEKGEADRALPLLRKAVNIAPEA 870
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 7-256 6.08e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 6.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563   7 PKEANLFkLIVKSYETKQYKKGLKAADAILKKFPDHGETlsmkgltlncmdrkseayelvrvgvkndikshvcWHVYGLL 86
Cdd:TIGR02917 430 LGRADLL-LILSYLRSGQFDKALAAAKKLEKKQPDNASL----------------------------------HNLLGAI 474

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  87 YRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSKAVE 166
Cdd:TIGR02917 475 YLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVA 554

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 167 ILEAYEGTLEDDYPPdnercehgemLLYKISLLEECGSLKRALEELHKKELKIVDKLAYKEQEVSLLVKLGLLEEAAKLY 246
Cdd:TIGR02917 555 WLEKAAELNPQEIEP----------ALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624

                         250
                  ....*....|
gi 1768482563 247 RVLLSMNPDN 256
Cdd:TIGR02917 625 KKLLALQPDS 634
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 95-170 6.42e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.46  E-value: 6.42e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1768482563  95 EAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSKAVEILEA 170
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLER 76
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
20-109 9.86e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.08  E-value: 9.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  20 YETKQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVgVKNDIKSHVCWHVYGLLYRSDREYREAIKC 99
Cdd:COG3063     3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKA-LKLDPNNAEALLNLAELLLELGDYDEALAY 81

                          90
                  ....*....|
gi 1768482563 100 YRNALRIDPD 109
Cdd:COG3063    82 LERALELDPS 91
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 3-144 1.10e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 1.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563   3 ASLPPKEANLFKLIVKSYET-KQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWH 81
Cdd:TIGR02917 560 AELNPQEIEPALALAQYYLGkGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALL 639

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1768482563  82 VYGLLYRSDREYREAIKCYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNH 144
Cdd:TIGR02917 640 LLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKA 702
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
56-143 1.70e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 1.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  56 MDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRSDREYREAIKcYRNALRIDPDNIEILRDLSLLQAQMRDLAGFVETRQ 135
Cdd:COG3063     5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83


                  ....*...
gi 1768482563 136 QLLTLKPN 143
Cdd:COG3063    84 RALELDPS 91
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
104-263 1.98e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.84  E-value: 1.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 104 LRIDPDNIEILRDLSLLQAQMRDLAGFVETRQQLLTLKPNHRMNWIGFAVAHHLNSNGSKAveiLEAYEGTLEDDypPDN 183
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEA---LADYEQALELD--PDD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563 184 ercehGEMLLYKISLLEECGSLKRALE------ELHKKELKIVDKLAYkeqevsLLVKLGLLEEAAKLYRVLLSMNPDNY 257
Cdd:COG0457    76 -----AEALNNLGLALQALGRYEEALEdydkalELDPDDAEALYNLGL------ALLELGRYDEAIEAYERALELDPDDA 144


                  ....*.
gi 1768482563 258 KYYEGL 263
Cdd:COG0457   145 DALYNL 150
TPR_1 pfam00515
Tetratricopeptide repeat;
84-110 2.93e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.94  E-value: 2.93e-04
                          10        20
                  ....*....|....*....|....*..
gi 1768482563  84 GLLYRSDREYREAIKCYRNALRIDPDN 110
Cdd:pfam00515   8 GNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 84-110 1.66e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.66e-03
                           10        20
                   ....*....|....*....|....*..
gi 1768482563   84 GLLYRSDREYREAIKCYRNALRIDPDN 110
Cdd:smart00028   8 GNAYLKLGDYDEALEYYEKALELDPNN 34
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 20-108 2.26e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.56  E-value: 2.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768482563  20 YETKQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKSEAYELVRVGVKNDIKSHVCWHVYGLLYRSDREYREAIKC 99
Cdd:COG5010    65 NKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAA 144


                  ....*....
gi 1768482563 100 YRNALRIDP 108
Cdd:COG5010   145 LQRALGTSP 153
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 80-109 3.74e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.58  E-value: 3.74e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1768482563  80 WHVYGLLYRSDREYREAIKCYRNALRIDPD 109
Cdd:pfam07719   4 LYNLGLAYYKLGDYEEALEAYEKALELDPN 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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