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Conserved domains on  [gi|1720787248|ref|XP_030134830|]
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alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 [Taeniopygia guttata]

Protein Classification

glycosyltransferase family 29 protein( domain architecture ID 690)

glycosyltransferase family 29 protein catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; uses a nucleotide monophosphosugar as the donor (CMP-NeuA) instead of a nucleotide diphosphosugar

CATH:  3.90.1480.20
CAZY:  GT29
EC:  2.4.99.-
Gene Ontology:  GO:0008373|GO:0006486
PubMed:  9334165

Graphical summary

 Zoom to residue level

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Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
GT29_ST6GALNAC5 cd23976
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are ...
 88-331 0e+00

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilize Sia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


:

Pssm-ID: 467704  Cd Length: 244  Bit Score: 530.60  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  88 GYISVLEHKPLKMHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILRNRNE 167
Cdd:cd23976     1 GYISIIDHKPLKMHCKSCALVTSSGHLTGSNRGNEIDETECVIRMNDAPTRGYGKDVGNKTSLRVIAHSSIQRILRNRNE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 168 LLNMSHGAVFIFWGPSSYMRRDGKGLVYNNLQLMNQILPQLKVYMISRHKMLQFDDLFKRETGKDRKISNTWLSTGWFTM 247
Cdd:cd23976    81 LLNVSQGTVFIFWGPSNYMRRDGKGLVYNNLQLMNQILPKLKVYTITRHKMLQFDELFKRETGKDRKISNTWLSTGWFTM 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 248 TIALELCERINVYGMVPPDFCRDPNHLSVPYHYYEPLGPDECTMYISHERGRKGSHHRFITEKRVFENWARTFDIRFFQP 327
Cdd:cd23976   161 IIALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPSGPDECTMYISHERGRKGSHHRFITEKRVFANWARTFNIHFYQP 240


                  ....
gi 1720787248 328 DWKP 331
Cdd:cd23976   241 DWKP 244
 
Name Accession Description Interval E-value
GT29_ST6GALNAC5 cd23976
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are ...
 88-331 0e+00

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilize Sia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467704  Cd Length: 244  Bit Score: 530.60  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  88 GYISVLEHKPLKMHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILRNRNE 167
Cdd:cd23976     1 GYISIIDHKPLKMHCKSCALVTSSGHLTGSNRGNEIDETECVIRMNDAPTRGYGKDVGNKTSLRVIAHSSIQRILRNRNE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 168 LLNMSHGAVFIFWGPSSYMRRDGKGLVYNNLQLMNQILPQLKVYMISRHKMLQFDDLFKRETGKDRKISNTWLSTGWFTM 247
Cdd:cd23976    81 LLNVSQGTVFIFWGPSNYMRRDGKGLVYNNLQLMNQILPKLKVYTITRHKMLQFDELFKRETGKDRKISNTWLSTGWFTM 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 248 TIALELCERINVYGMVPPDFCRDPNHLSVPYHYYEPLGPDECTMYISHERGRKGSHHRFITEKRVFENWARTFDIRFFQP 327
Cdd:cd23976   161 IIALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPSGPDECTMYISHERGRKGSHHRFITEKRVFANWARTFNIHFYQP 240


                  ....
gi 1720787248 328 DWKP 331
Cdd:cd23976   241 DWKP 244
Glyco_transf_29 pfam00777
Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to ...
 92-282 4.86e-32

Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to glycosyltransferase family 29.


Pssm-ID: 459935  Cd Length: 256  Bit Score: 120.40  E-value: 4.86e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  92 VLEHKPLK-MHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVI-AHSSIQRILRNRNE-- 167
Cdd:pfam00777  32 LPKVSPFDnKRCRRCAVVGNGGILRGSGCGKEIDSHDFVIRCNLAPTKGYEKDVGSKTTLRTMnPESAIDSKYGNLGFsh 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 168 --------LLNMSHG------AVFIFWGPSSYMRRdgkglVYNNLQLMNQILPQLKVYMISRHKMLQFDDLFKRETGKDR 233
Cdd:pfam00777 112 prdpfvefVLVPFKGrdllwlPAFLTKGNVSRSLR-----VLYTLKEVKIPVDPDKVLFLHPDFLRYVANFWLRSHGLKG 186

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1720787248 234 KIsntwLSTGWFTMTIALELCERINVYGMVPPDfcrdpNHLSVPYHYYE 282
Cdd:pfam00777 187 RR----PSTGLLMLSLALHLCDEVSLYGFGPFL-----DSRGNSHHYYD 226
 
Name Accession Description Interval E-value
GT29_ST6GALNAC5 cd23976
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are ...
 88-331 0e+00

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilize Sia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467704  Cd Length: 244  Bit Score: 530.60  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  88 GYISVLEHKPLKMHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILRNRNE 167
Cdd:cd23976     1 GYISIIDHKPLKMHCKSCALVTSSGHLTGSNRGNEIDETECVIRMNDAPTRGYGKDVGNKTSLRVIAHSSIQRILRNRNE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 168 LLNMSHGAVFIFWGPSSYMRRDGKGLVYNNLQLMNQILPQLKVYMISRHKMLQFDDLFKRETGKDRKISNTWLSTGWFTM 247
Cdd:cd23976    81 LLNVSQGTVFIFWGPSNYMRRDGKGLVYNNLQLMNQILPKLKVYTITRHKMLQFDELFKRETGKDRKISNTWLSTGWFTM 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 248 TIALELCERINVYGMVPPDFCRDPNHLSVPYHYYEPLGPDECTMYISHERGRKGSHHRFITEKRVFENWARTFDIRFFQP 327
Cdd:cd23976   161 IIALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPSGPDECTMYISHERGRKGSHHRFITEKRVFANWARTFNIHFYQP 240


                  ....
gi 1720787248 328 DWKP 331
Cdd:cd23976   241 DWKP 244
GT29_ST6GALNAC3_4_5_6 cd23965
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3, 4, 5 and 6; ST6GalNAc family ...
 102-327 5.63e-126

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3, 4, 5 and 6; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acidand the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, bytransfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substratespecificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467693  Cd Length: 225  Bit Score: 360.40  E-value: 5.63e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 102 CKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILRNRNELL-NMSHGAVFIFW 180
Cdd:cd23965     1 CDTCALVSSSGQLLGSGAGKEIDSADCVIRMNDAPTRGYEKDVGRRTTIRVVSHSSLPRLLRNAILLLaGTRAPTVVVFW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 181 GPSSYMRRDGKGlVYNNLQLMNQILPQLKVYMISRHKMLQFDDLFKRETGKDRKISNTWLSTGWFTMTIALELCERINVY 260
Cdd:cd23965    81 GPETKMNKDGAG-KYNLLRSLSKKYPDVEFYSLTPEKMDYADELFEKETGKSRIKSGTWLSTGWFTMLLALDVCDEIKVY 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720787248 261 GMVPPDFCRDPNHLSVPYHYYEPLGPDECTMYISHERGRKGsHHRFITEKRVFENWARTFDIRFFQP 327
Cdd:cd23965   160 GMVPENYCREHPNSKVPYHYYEPGGLKECTYYNYHENALKG-GHRFITEKAVFARWAKKYNITFHHP 225
GT29_ST6GALNAC6 cd23978
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are ...
 102-329 1.91e-122

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467706  Cd Length: 229  Bit Score: 351.46  E-value: 1.91e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 102 CKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILRNRNELLNMSHGAVFIFWG 181
Cdd:cd23978     1 CHQCALITSSSHLLGTSLGPEIDQTECTIRMNDAPTTGYEKDVGNKTTLRVVAHSSVYRVLRRPQEFLNRTPETTLIFWG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 182 PSSYMRRDGKGLVYNNLQLMNQILPQLKVYMISRHKMLQFDDLFKRETGKDRKISNTWLSTGWFTMTIALELCERINVYG 261
Cdd:cd23978    81 PPNKMQKDGKSNLFRIIQRASMTFPNMSAFVVSPRRMRQFDDLFRGETGRDRKKSHSWLSTGWFTMVIAVELCDNVHVYG 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720787248 262 MVPPDFCRD-PNHLSVPYHYYEPLGPDECTMYISHERGRKGSHHRFITEKRVFENWARTFDIRFFQPDW 329
Cdd:cd23978   161 MVPPNYCSKrPTPKKMPYHYYEPKGPDECVTYIQNEHGRRGNHHRFITEKRVFARWAEHYNITFSHPSW 229
GT29_ST6GALNAC4 cd23977
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; ST6GalNAc family members are ...
 102-329 4.70e-97

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467705  Cd Length: 228  Bit Score: 287.14  E-value: 4.70e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 102 CKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILRNRNELLNMSHGAVFIFWG 181
Cdd:cd23977     1 CRRCAVVSSSGQMLGSGLGPEIDQQECVLRMNVAPTAGYEADVGNRSSLRVVSHTSVPLLLRNQGYFFQQSRDTKYVIWG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 182 PSSYMRRDGKGLVYNNLQLMNQILPQLKVYMISRHKMLQFDDLFKRETGKDRKISNTWLSTGWFTMTIALELCERINVYG 261
Cdd:cd23977    81 PERNMDRDGGGKTYRALLTLAKMYPHLQVYTLTEEKMAYCDGVFQNETGKNRMKSGSFLSTGWFTMILALELCEEILVYG 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720787248 262 MVPPDFCRDPNHLSVPYHYYEPLGPDECTMYISHERGRKGShHRFITEKRVFENWARTFDIRFFQPDW 329
Cdd:cd23977   161 MVSDSYCRNKNHSSVPYHYYEKGRLDECRMYLVHERAPRGG-HRFITEKAIFSRWAKRKKIRFAHPSW 227
GT29_ST6GALNAC3 cd23975
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; ST6GalNAc family members are ...
 102-329 3.62e-85

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467703  Cd Length: 226  Bit Score: 256.78  E-value: 3.62e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 102 CKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILRNRNELLNMSHGAVFIFWG 181
Cdd:cd23975     1 CDLCAVVSNSGQMVGQKVGAEIDQSSCIWRMNNAPTKGYEEDVGKRTTIRVVSHTSVPLLLKNPDYFFKETNETIYVIWG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 182 PSSYMRRDGKGLVYNNLQLMNQILPQLKVYMISRHKMLQFDDLFKRETGKDRKISNTWLSTGWFTMTIALELCERINVYG 261
Cdd:cd23975    81 PFRNMRKDGKGIVYNMLKKAVESYPQAKIYVTTEKRMSYCDTVFKKETGKDRVQSGSYLSTGWFTLILAMDACYGIHVYG 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720787248 262 MVPPDFCRDPNHLSVPYHYYEPlGPDECTMYISHERGRKGShHRFITEKRVFENWARTFDIRFFQPDW 329
Cdd:cd23975   161 MINDTYCKTEGYRKVPYHYYEP-GRDECDEYFLHENAPYGG-HRFITEKKVFAKWAKKHPITFTHPNW 226
GT29 cd19952
glycosyltransferase family 29; Glycosyltransferase family 29 members (also called ...
 105-316 5.49e-38

glycosyltransferase family 29; Glycosyltransferase family 29 members (also called sialyltransferases) are enzymes that transfer sialic acid to oligosaccharide, each having specificity for a certain sugar substrate.


Pssm-ID: 467690  Cd Length: 193  Bit Score: 134.41  E-value: 5.49e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 105 CALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILRN-RNELLNMS--HGAVFIFWG 181
Cdd:cd19952     1 CAVVGNSGILLGSEYGKEIDSHDAVFRFNQAPTKGFEKDVGSKTTFRVLNSKWAGFYLRGpRCGCHPLPleEEVVLILSR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 182 PSSYMRRDGK---GLVYNNLQLMNQILPQLKVYMISRhkmlqfddlFKRETGKDRKISNTwLSTGWFTMTIALELCERIN 258
Cdd:cd19952    81 AAAADFKRLKrrkKRHDNAVLLLTDPAPDLLSYVRKR---------LEKLGLKSFFGGNA-PSSGLLAVLLALQLCDSVD 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720787248 259 VYGmvppdFCRDPNH-LSVPYHYYEPLGPdectmyisherGRKGSHHRFITEKRVFENW 316
Cdd:cd19952   151 LYG-----FGVDSGHaPKVPYHYYDLVEA-----------EEGTAVHSFDLEAELLRAL 193
GT29_ST8SIA cd23963
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ST8Sia family members are ...
 103-309 1.42e-32

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ST8Sia family members are alpha-N-acetylneuraminidealpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The family is subdivided into 3 classes of enzymes, depending on their catalytic activiy, the mono-STs (ST8Sia1, ST8Sia5 and ST8Sia6), the oligo-ST(ST8Sia3), and the poly-STs (ST8Sia2 and ST8Sia4). The ST8Sia family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467691  Cd Length: 274  Bit Score: 122.37  E-value: 1.42e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 103 KSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRIL------RNRNELLN-MSHGA 175
Cdd:cd23963    64 KTCAVVGNSGILLGSGCGKEIDSHDFVIRCNLPPIKGFEKDVGRKTNLTTLNPSILKRRYnslkknRDRDKFLNrLKEYN 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 176 VFIFWGPSSYMRRDGKgLVYNNLQLMNQILPQLKV-YMISRHKMLQFDdlFKRETGKDRkisntWLSTGWFTMTIALELC 254
Cdd:cd23963   144 GSILWYPKFSFKSSTN-LLLKAARALKKNGLNLTVvYSNPEHFLAVQK--FWKRRGLEK-----RPSTGLYLVSLALTFC 215

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1720787248 255 ERINVYGMVPpdFCRDPNHLSVPYHYYEPLGPDEctmyishergrKGSHHRFITE 309
Cdd:cd23963   216 DEIHLYGFWP--FPTDPNGRPVPYHYYDDLSPST-----------KNKVHNMPEE 257
Glyco_transf_29 pfam00777
Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to ...
 92-282 4.86e-32

Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to glycosyltransferase family 29.


Pssm-ID: 459935  Cd Length: 256  Bit Score: 120.40  E-value: 4.86e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  92 VLEHKPLK-MHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVI-AHSSIQRILRNRNE-- 167
Cdd:pfam00777  32 LPKVSPFDnKRCRRCAVVGNGGILRGSGCGKEIDSHDFVIRCNLAPTKGYEKDVGSKTTLRTMnPESAIDSKYGNLGFsh 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 168 --------LLNMSHG------AVFIFWGPSSYMRRdgkglVYNNLQLMNQILPQLKVYMISRHKMLQFDDLFKRETGKDR 233
Cdd:pfam00777 112 prdpfvefVLVPFKGrdllwlPAFLTKGNVSRSLR-----VLYTLKEVKIPVDPDKVLFLHPDFLRYVANFWLRSHGLKG 186

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1720787248 234 KIsntwLSTGWFTMTIALELCERINVYGMVPPDfcrdpNHLSVPYHYYE 282
Cdd:pfam00777 187 RR----PSTGLLMLSLALHLCDEVSLYGFGPFL-----DSRGNSHHYYD 226
GT29_ST6GAL1_2 cd23968
beta-galactoside alpha-2,6-sialyltransferase 1 and 2; ST6Gal family members are ...
 103-313 4.20e-29

beta-galactoside alpha-2,6-sialyltransferase 1 and 2; ST6Gal family members are beta-galactosidealpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acidand the terminal galactose residue of a glycochain, by transfering sialic acid fromCMP-Sia. The ST6Gal family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467696  Cd Length: 266  Bit Score: 112.75  E-value: 4.20e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 103 KSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHssiQRILRNRNELLN---MSHGAVFIf 179
Cdd:cd23968    46 NTCAVVSSSGALLGSKLGKEIDSHDAVLRFNDAPTKGFEKDVGSKTTLRLINS---QILSKPEFNFLTdplYRNVTLLV- 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 180 WGPSSYMRRDGKGL------VYNNLQLMNQILPQLKVYMISRHKMLQFDDLFKRETGkdRKISNTWLSTGWFTMTIALEL 253
Cdd:cd23968   122 WDPSSYNVNLEKWYkkpdfdFFPNYIKYRRRHPEEPFYLIDPRFLWRLWDILQEYTP--EKIKPNPPSSGFIGIVLMLHL 199

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720787248 254 CERINVYGMVPP----DFCrdpnhlsvpyHYYEPLGPDECTMyishergrkGSHHRFITEKRVF 313
Cdd:cd23968   200 CDWVDVYEYVPSvrqtDRC----------HYYDVEKDLACTL---------GAWHPLAAEKLLV 244
GT29_ST8SIA2 cd23987
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2; ST8Sia2 is a polysialyltransferase ...
 97-284 4.73e-22

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2; ST8Sia2 is a polysialyltransferase that can synthesize polysialic acid on neural cell adhesion molecules (NCAMs). ST8Sia2 catalyzes shorter polysialic acid formation of NCAMs than ST8Sia4. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia and they belong to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467715  Cd Length: 278  Bit Score: 93.85  E-value: 4.73e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  97 PLK-MHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILRN------RNELL 169
Cdd:cd23987    58 PLKnKHFKTCAIVGNSGILLNSGCGREIDSHDFVIRCNLAPVEEYAKDVGTKTDLVTMNPSVVQRAFEDlvnetwKEKFL 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 170 NMSHG-AVFIFWGPsSYMRRDGKGLV--YNNLQLMNQI-----LPQLKVYMISRHKMLQFDDLFKRETgkdrkisntwls 241
Cdd:cd23987   138 QRLQSlNGSILWIP-AFMAKGGEERVewVNDLILKHHInvrtaYPSLRLLHAVRGYWLTNKVHIKRPT------------ 204

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1720787248 242 TGWFTMTIALELCERINVYGMVPpdFCRDPNHLSVPYHYYEPL 284
Cdd:cd23987   205 TGLLMYTLATRFCNRIHLYGFWP--FPRDQNQNPVKYHYYDSL 245
GT29_ST8SIA3_oligo cd23970
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3; Alpha-N-acetylneuraminide alpha-2, ...
 98-285 7.63e-22

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3 synthesizes polysialic acid and has been shown to autopolysialylate. ST8Sia3 utilizes the Siaalpha2,3Galbeta1,4GlcNAc structure on N-glycans of glycoproteins and glycolipids as acceptor substrates. ST8Sia family members are alpha-N-acetylneuraminidealpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acidand the terminal sialic acid residues of glycochains, by transfering sialic acidfrom CMP-Sia and they belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467698  Cd Length: 284  Bit Score: 93.61  E-value: 7.63e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  98 LKMHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRIL--------RNRNELL 169
Cdd:cd23970    64 QNKHYNTCAVVGNSGILTNSQCGNEIDKSDFVFRCNFAPTEGFEKDVGRKTNLTTFNPSILEKYYnnlltiqdRNNFFLS 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 170 NMSHGAVfIFWGPS---SYMRRDGKGLVYNNLQLMNQILPQLKvymISRHKMLQFDDLFKRETGKDRKisntwLSTGWFT 246
Cdd:cd23970   144 LKKLDGA-ILWIPAfffHTSATVTRTLVDFFVEHRGQLKVQLA---WPGNIMQHVNRYWKTKHLSPKR-----LSTGILM 214

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1720787248 247 MTIALELCERINVYGMVPpdFCRDPNHLSVPYHYYEPLG 285
Cdd:cd23970   215 YTLASAICEEIHLYGFWP--FGFDPTGTPLPYHYYDKKG 251
GT29_ST3GAL3_4_5_6 cd23967
beta-galactoside alpha-2,3-sialyltransferase 3,4,5 and 6; ST3GAL family transfers sialic acid ...
 102-311 3.44e-21

beta-galactoside alpha-2,3-sialyltransferase 3,4,5 and 6; ST3GAL family transfers sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL3 and 4 utilize bothGalbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates. ST3GAL5 is also known as GM3 ganglioside synthase. ST3GAL6 utilizes the Galbeta1,4GlcNAc on glycoproteins and glycolipids as an acceptor. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467695  Cd Length: 205  Bit Score: 90.04  E-value: 3.44e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 102 CKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSS--IQRILRNRNELLnmshgaVFIF 179
Cdd:cd23967     2 CRRCVVVGNGGVLKGKSLGSVIDKYDVVIRMNDAPVKGYEKDVGSKTTFRMFYPESafRDPEEYDSDWLL------VLVP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 180 WGPSSY-------MRRDGKGLVY-------------NNLQLMN-QILPQLKVYMISrhkmlqfddlfKRETGKDRKIsnt 238
Cdd:cd23967    76 FKSMDLlwlqaviKGKKPNGKGGfwkkiatsvpkppKKIRILNpYILQEAAFDLIG-----------LPMNGKQGKN--- 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720787248 239 WLSTGWFTMTIALELCERINVYGmvppdFCRDPNHLSVPYHYYEPLgpdecTMYIShergRKGSHHRFITEKR 311
Cdd:cd23967   142 VPTTGIIAIVMALHYCDEVDIAG-----FGYDPSDPNAPLHYYDSL-----TMKAI----KRSWTHNVTKEKK 200
GT29_ST8SIA_mono cd23971
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1, 5 and 6; ST8 Sia family members are ...
 103-286 4.32e-21

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1, 5 and 6; ST8 Sia family members are alpha-N-acetylneuraminidealpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The family is subdivided into 3 classes of enzymes, depending on theircatalytic activiy, the mono-STs (ST8Sia1, ST8Sia5 and ST8Sia6), the oligo-ST(ST8Sia3), and the poly-STs (ST8Sia2 and ST8Sia4). The ST8Sia family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467699  Cd Length: 271  Bit Score: 91.16  E-value: 4.32e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 103 KSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTrGYGTDVGNKTSLrVIAHSSiqrILRNRNELLNMSHGAvFI---- 178
Cdd:cd23971    65 KTCAVVGNGGILKNSSCGREIDSADFVIRCNLPPL-NDSKDVGSKTNL-VTANPS---ILREKFHNLKKRRRP-FVermk 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 179 ------FWGPS-SYMRRDGKGL-VYNNLQlmnQILPQLKVYMISRHKMLQFDDLFKRETGKDRKisntwLSTGWFTMTIA 250
Cdd:cd23971   139 vygnalLLLPAfSYTSNTEPSLrALYTLE---DFGSPQKVLFFNPEYLRNLSRYWKSKGLKARR-----LSTGLMLVSAA 210

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1720787248 251 LELCERINVYGMVPpdFCRDPNHLSVPYHYYEPLGP 286
Cdd:cd23971   211 LELCENVHLYGFWP--FSTDLDGNPISHHYYDNVLP 244
GT29_ST8SIA_poly cd23969
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2 and 4; ST8Sia2 and 4 are known to be ...
 94-313 1.40e-19

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2 and 4; ST8Sia2 and 4 are known to be polysialyltransferases, and they can synthesize polysialic acid on neural cell adhesion molecules (NCAMs). ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia and they belong to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467697  Cd Length: 276  Bit Score: 87.08  E-value: 1.40e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  94 EHKPLK-MHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSL-----RVIAH-------SSIQR 160
Cdd:cd23969    55 EVSPLKgKHFRTCAVVGNSGILLNSGCGQEIDSHDFVIRCNLAPVEGYEKDVGTKSNLttmnpSVIPHaygdlvnATDKE 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 161 ILRNRNELLNMShgavfIFWGPsSYMRRDGKGLV-YNNLQLMNQILPqLKVYMISRHkMLQfddlfkretgkdrKISNTW 239
Cdd:cd23969   135 KFVERLRQLGDS-----ILWIP-AFVSKGGEEHVqWTNEIILKHKLN-VKTAYPPLR-LNH-------------AIRGYW 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 240 L---------STGWFTMTIALELCERINVYGMVPpdFCRDPNHLSVPYHYYEPLGpdectmYIShergrKGSHHRFITEK 310
Cdd:cd23969   194 LttkfrikrpSTGLLMYTLATRFCDEIHLYGFYP--FSEDGNGRAVKYHYYDNRK------YLT-----TARPHKMPEEF 260


                  ...
gi 1720787248 311 RVF 313
Cdd:cd23969   261 RAL 263
GT29_ST6GAL2 cd23986
beta-galactoside alpha-2,6-sialyltransferase 2; ST6Gal family members are beta-galactoside ...
 77-310 3.06e-19

beta-galactoside alpha-2,6-sialyltransferase 2; ST6Gal family members are beta-galactoside alpha-2,3-sialyltransferases that catalyze an alpha2,6-linkage between sialic acid and the terminal galactose residue of a glycochain, by a transfering sialic acid from CMP-Sia. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467714  Cd Length: 270  Bit Score: 86.04  E-value: 3.06e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  77 PALPVGAGLLEGYisvlehkplkmhcKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAhs 156
Cdd:cd23986    37 PKIPLSKLHLRGF-------------RSCAVVTSAGAILNSSLGKEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIIN-- 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 157 siQRILRNRNELLNMS---HGAVFIFWGPSSYMRRDGKGLVYNNLQLMNQIL------PQLKVYMISRHKMLQFDDLFKR 227
Cdd:cd23986   102 --SQILTNPNHHFIDSslyKDVILVAWDPAPYSANLHKWYKKPDYNLFTPYVqyrkrnPNQPFYILHPKFIWQLWDIIQE 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 228 ETgkDRKISNTWLSTGWFTMTIALELCERINVYGMVPP----DFCrdpnhlsvpyHYYEPLGPDECTMyishergrkGSH 303
Cdd:cd23986   180 NT--QEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSvrqtDLC----------HYHERYYDAACTL---------GAY 238


                  ....*..
gi 1720787248 304 HRFITEK 310
Cdd:cd23986   239 HPLLYEK 245
GT29_ST6GAL1 cd23985
beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside ...
 79-310 3.97e-18

beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the terminal galactose residue of a glycochain, by transfering sialic acid from CMP-Sia. ST6Gal1 play important roles in the immune system. The ST6Gal family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467713  Cd Length: 266  Bit Score: 82.83  E-value: 3.97e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  79 LPVGAGLLEGYisvLEHKPLKM---HCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIah 155
Cdd:cd23985    22 FPFNTSEWEGY---LPKKSLREevgPLGRCAVVSSAGSLKSSGLGREIDSHDAVLRFNGAPTAGFQQDVGTKTTIRLI-- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 156 sSIQRILRNRNELLNMS--HGAVFIFWGPSSY--------MRRDGKglVYNNLQLMNQILPQLKVYMISRHKMLQFDDLF 225
Cdd:cd23985    97 -NSQLVTTEKHKFLKDSlyNEGILIVWDPAPYhsdipewyKNPDYN--FFENYKTYRRLNPNQPFYILHPQMQWELWDII 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 226 KRETGKDrkISNTWLSTGWFTMTIALELCERINVYGMVPP----DFCrdpnhlsvpyHYYEPLGPDECTMyishergrkG 301
Cdd:cd23985   174 QENSPEE--IQPNPPSSGMLGIILMMTLCDQVDVYEFLPSkrktDVC----------HYYQKFFDRACTM---------G 232


                  ....*....
gi 1720787248 302 SHHRFITEK 310
Cdd:cd23985   233 AYHPLLYEK 241
GT29_ST8SIA1 cd23989
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1; Alpha-N-acetylneuraminide alpha-2, ...
 97-287 5.69e-18

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1 (also known as ganglioside GD3 synthase) adds sialic acids to GM3 ganglioside. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze analpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The ST8Sia family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467717  Cd Length: 272  Bit Score: 82.57  E-value: 5.69e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  97 PLKMHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAP-TRGYGTDVGNKTSLrVIAHSSI-----QRILRNRNELL- 169
Cdd:cd23989    58 PLQLPLKKCSVVGNGGILKNSGCGQQIDRADFVMRCNLPPlSREYTDDVGTKTQL-VTANPSIidkrfQNLLWSRKSFVe 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 170 NMS-HGAVFIFWgPSSYMRRDGKglvynnlqlmnqilPQLKVYMI-----SRHKMLQFDDLFKRETG---KDRKISNTWL 240
Cdd:cd23989   137 SMKvYGRSYIYM-PAFSMKTGTD--------------PSLRVYYTladvgANQTVLFANPNFLRNVGkfwKSKGVHAKRL 201

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1720787248 241 STGWFTMTIALELCERINVYGMVPpdFCRDPNHLSVPYHYYEPLGPD 287
Cdd:cd23989   202 STGLFLVSAALGLCEEVTIYGFWP--FSVDLDERTISHHYYDNVLPD 246
GT29_ST8SIA4 cd23988
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 4; ST8Sia4 is a polysialyltransferase ...
 94-284 7.20e-18

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 4; ST8Sia4 is a polysialyltransferase that can synthesize polysialic acid on neural cell adhesion molecules (NCAMs). ST8Sia4 catalyzes longer polysialicacid formation of NCAMs than ST8Sia2. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia and they belong to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467716  Cd Length: 278  Bit Score: 82.31  E-value: 7.20e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  94 EHKPLK-MHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRI---LRNRNELL 169
Cdd:cd23988    55 EVSPMKnRRFKTCAVVGNSGILLDSGCGKEIDSHDFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAfggFRNESDRE 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 170 NMSHGAVF----IFWGPsSYMRRDGKGLV--YNNLQLMNQI-----LPQLKVYMISRHKMLQFDDLFKREtgkdrkisnt 238
Cdd:cd23988   135 KFVHRLSMlndsVLWIP-AFMVKGGEKHVewVNALILKNKLkvrtaYPSLRLIHAVRGYWLTNKVNIKRP---------- 203

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1720787248 239 wlSTGWFTMTIALELCERINVYGMVPpdFCRDPNHLSVPYHYYEPL 284
Cdd:cd23988   204 --STGLLMYTLATRFCDEIHLYGFWP--FPKDANGNPVKYHYYDDL 245
GT29_ST3GAL5 cd23983
beta-galactoside alpha-2,3-sialyltransferase 5; ST3GAL family transfers sialic acid from ...
 101-284 1.45e-15

beta-galactoside alpha-2,3-sialyltransferase 5; ST3GAL family transfers sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL5 is also known as GM3 ganglioside synthase. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467711  Cd Length: 211  Bit Score: 74.39  E-value: 1.45e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 101 HCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVI----AHSSIQRILRNR----------- 165
Cdd:cd23983     1 TCRRCVVVGSGGILHGLELGHLLDQFDIVIRLNNAPVQGYSQDVGNKTTIRMTypegAPKSEQEYDPTSlfvavlfksvd 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 166 -NELLNMSHGAVFIFWGPSSYMRRDGKGLVYNNLQLmnQILPQLKVYMISRhKMLQFDDLFKRETGKDRKISntwlSTGW 244
Cdd:cd23983    81 fAWLKAMVKKEPLSFWSRLFFWKEVADSIPLKPSQF--RILNPLIIKETAL-DILQYPEPQSRLWGWDKNVP----TLGV 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1720787248 245 FTMTIALELCERINVYGmvppdFCRDPNHLSVPYHYYEPL 284
Cdd:cd23983   154 TAVVLATHLCDEVSLAG-----FGYDLSQPHAPLHYYDSV 188
GT29_ST3GAL1_2 cd23966
beta-galactoside alpha-2,3-sialyltransferase 1 and 2; ST3GAL family transfer sialic acid from ...
 101-326 5.25e-15

beta-galactoside alpha-2,3-sialyltransferase 1 and 2; ST3GAL family transfer sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL1 and 2 preferentially utilize the Galbeta1,3GalNAc on O-glycans of glycoproteins (core1O-glycans) and on glycolipids as an acceptor substrate, respectively. Members ofthis family belong to glycosyltransferase family 29.


Pssm-ID: 467694  Cd Length: 276  Bit Score: 74.24  E-value: 5.25e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 101 HCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRiLRNRNELLNMSHGAVFIFW 180
Cdd:cd23966    76 RCRRCAVVGNSGNLRGSRYGKLIDSHDFVIRMNKAPTKGFEKDVGSKTTHHFMYPESAVD-LDPGVHLVLVPFKVLDLQW 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 181 GPSS---------YMRrdgkglVYNNLQLmnqilpqlkvymiSRHKMLQFDDLFKREtgkdrkISNTWL-------STGW 244
Cdd:cd23966   155 LISAlttgeitrtYTP------VKRFIKA-------------DKDKVLVINPAFIKY------VHDNWTehhgrypSTGF 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 245 FTMTIALELCERINVYGMvppdfcrDPNHLSVPYHYYEPLgpdectmyISHERGRKGSHHRFITEKRVFENWARTFDIRF 324
Cdd:cd23966   210 LALIFALHICDEVSVFGF-------GADSKGNWHHYWEKN--------RSAGAFRKTGVHDADFESDIIKKLAKEGKIRV 274


                  ..
gi 1720787248 325 FQ 326
Cdd:cd23966   275 YR 276
GT29_ST3GAL4 cd23982
beta-galactoside alpha-2,3-sialyltransferase 4; ST3GAL family transfers sialic acid from ...
 102-282 1.97e-14

beta-galactoside alpha-2,3-sialyltransferase 4; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL4 can utilize both Galbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates, but prefers the Galbeta1,4GlcNAc. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467710  Cd Length: 204  Bit Score: 71.23  E-value: 1.97e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 102 CKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQ---RILRNRNELLnmshgaVFI 178
Cdd:cd23982     2 CRRCVVVGNGHNLKNSSLGDVIDSYDVVIRLNDAPVRGFEKDVGSKTTIRLFYPESAQfdpGIENDPDTLL------VLV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 179 FWGPSSYM---------RRDGKGLVYNNLQLMNQILPQLKV----YM-ISRHKMLQFddlfkreTGKDRKIsnTWLSTGW 244
Cdd:cd23982    76 PFKPLDFYwlyeilsneKRVRKGFWKQPPRIWDANPKQIRIlnpyYTyVAATKLLQV-------PGQRKKK--QKPTTGL 146

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1720787248 245 FTMTIALELCERINVYGMVPPDfCRDPNHlsvPYHYYE 282
Cdd:cd23982   147 LAITLALHLCDEVHIAGFGYPD-NGNSNQ---PIHYYN 180
GT29_ST6GALNAC1 cd23973
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6GalNAc family members are ...
 95-326 5.55e-14

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc1 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467701  Cd Length: 309  Bit Score: 71.71  E-value: 5.55e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  95 HKPLKMHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRV-IAHSSIQ--RILRNRNeLLNM 171
Cdd:cd23973    76 SPPGGDGCIRCAVVGNGGILNGSKMGQEIDSHDYVFRVNGAVIKGYEEDVGTRTSFYVhTAHSITSslMILQKRG-FKNI 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 172 SHGA----VFIFWGPssymrRDgkglvYNNLQ--LMNQILPQLKVYmiSRHKMLQFDDLFKRET---------------- 229
Cdd:cd23973   155 PQDKdikyILFPEGP-----RD-----YQWLEalLKNKTIPSGAYY--GRRPRSYFSGDFTEDKylvlhpdflryvknrf 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 230 --GKDRKISNTWL---STGWFTMTIALELCERINVYGMVPPDFCRDPNhlsvpyHYYEpLGPDECTMYISHErgrkgshh 304
Cdd:cd23973   223 lrSKTLKGKYWAIyrpTTGAFLLLTALHLCDTVSAYGFITEDYRKYPD------HYYD-KKKTKLVFYINHD-------- 287

                         250       260
                  ....*....|....*....|....*
gi 1720787248 305 rFITEKRVfenWARTFD---IRFFQ 326
Cdd:cd23973   288 -FRLEKKL---WKRLHDekiIKLYQ 308
GT29_ST3GAL6 cd23984
beta-galactoside alpha-2,3-sialyltransferase 6; ST3GAL family transfers sialic acid from ...
 102-282 4.51e-13

beta-galactoside alpha-2,3-sialyltransferase 6; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL6 utilizes the Galbeta1,4GlcNAc on glycoproteins and glycolipids as an acceptor. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467712  Cd Length: 206  Bit Score: 67.46  E-value: 4.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 102 CKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSI-------------------QRIL 162
Cdd:cd23984     2 CKKCVVVGNGGVLRNKSLGKKIDSYDVIIRMNNGPVIGYENDVGKRTTFRLCYPESIfsdpshydpnttvvlipfkPHDL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 163 RNRNELLNMSHGAVFIFWgpssymRRDGKGLVYNNLQLmnQILPQLKVYmISRHKMLQFDDLFKREtgkDRKISNTwlsT 242
Cdd:cd23984    82 RWLLDLLMGKKVSAKGFW------KKPALNLIYKPNQI--RILNPFILR-IAAYELLHFPKRFPKE---KKPKHPT---T 146

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1720787248 243 GWFTMTIALELCERINVYGmvppdFCRDPNHLSVPYHYYE 282
Cdd:cd23984   147 GIIAITLALHICNEVHIAG-----FKYDFSNLNSTLHYYG 181
GT29_ST8SIA6 cd23991
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 6; alpha-N-acetylneuraminide alpha-2, ...
 103-286 1.28e-11

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 6; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 6 (also known as alpha-2,8-sialyltransferase 8F) prefers O-glycans to N-glycans or glycolipids as acceptor substrates. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The ST8Sia family belongs to glycosyltransferase family 29(GT29).


Pssm-ID: 467719  Cd Length: 273  Bit Score: 64.00  E-value: 1.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 103 KSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRG-YGTDVGNKTSLrVIAHSSI-----QRILRNRNELLN--MSHG 174
Cdd:cd23991    65 KQCAVVGNGGILKNSSCGAEIDQADFVFRCNLPPTGGnISKDVGSKTNL-VTANPSIisikyAKLNERRKPFLEtvSVYG 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 175 AVFIFWGPSSYmrRDGKGLVYNNLQLMNQILPQLKVymISRH-KMLQFDDLFKRETGkdrkISNTWLSTGWFTMTIALEL 253
Cdd:cd23991   144 DAFLLLPAFSY--RSNTALSFKVYYTLEDFKAKQKV--IFFHpIYLKHLAQFWRSKG----VQVYRLSTGLMITSAALEL 215

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1720787248 254 CERINVYGMVPpdFCRDPNHLSVPYHYYEPLGP 286
Cdd:cd23991   216 CEEVKLYGFWP--FSKNTEGKPISHHYYDNQLP 246
GT29_ST6GALNAC1_2 cd23964
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 and 2; ST6GalNAc family members ...
 89-282 1.37e-11

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 and 2; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc1 and 2 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467692  Cd Length: 292  Bit Score: 64.20  E-value: 1.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  89 YISVLEHKPLKmhCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVI-AHSSIQRILRNrne 167
Cdd:cd23964    71 YMFVLRGGRPR--CIRCAVVGNGGILNGSGKGKEIDAHDYVFRVNHALTKGFEKDVGTKTSFYTFfPESLHNSLLKH--- 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 168 lLNMSHGAVFIFwgpSSYMRRDgkgLVYNNLQLMNQILPQLKVYMISRHKMLQFD-----------DLFkretgkdRKIS 236
Cdd:cd23964   146 -VPQDKDTKYLF---IPFKIRD---YDYLDAVLSGKPVPDGCDKGKRPPPLFGPKlnatnvrllhpDFI-------RYLF 211

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1720787248 237 NTWL--------STGWFTMTIALELCERINVYGmvppdFCRDPNHlsvPYHYYE 282
Cdd:cd23964   212 NRWLnsstsyrpTTGALMLLTALHTCDQVSVYG-----FGYDPRF---SLHYYD 257
GT29_ST3GAL3 cd23981
beta-galactoside alpha-2,3-sialyltransferase 3; ST3GAL family transfers sialic acid from ...
 102-282 9.66e-11

beta-galactoside alpha-2,3-sialyltransferase 3; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL3 can utilize both Galbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates, but prefers the Galbeta1,3GlcNAc. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467709  Cd Length: 207  Bit Score: 60.71  E-value: 9.66e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 102 CKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVI-AHSSIQRILRNRNEllnmshgAVFIFW 180
Cdd:cd23981     2 CRRCIIVGNGGVLANKSLGSKIDDYDVVVRLNSAPVKGFEKDVGSKTTLRITyPEGAIQKPEQYEKD-------SLFVLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 181 GpssYMRRDGKGLVY----NNLQLMNQILPQLKVYMISR-HKMLQFDDLFKRETGKD---RKISNTWL------STGWFT 246
Cdd:cd23981    75 G---FKWQDFKWLKYivykEKVSASDGFWKSVATRVPREpHEIRILNPYFIQEAAFSfigLPFNNGLMgrgnipTLGSVA 151

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1720787248 247 MTIALELCERINVYGmvppdFCRDPNHLSVPYHYYE 282
Cdd:cd23981   152 ITMALHNCDEVAVAG-----FGYDMNTPNAPLHYYE 182
GT29_ST3GAL1 cd23980
beta-galactoside alpha-2,3-sialyltransferase 1; ST3GAL family transfer sialic acid from ...
 84-261 1.21e-09

beta-galactoside alpha-2,3-sialyltransferase 1; ST3GAL family transfer sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL1 preferentially utilizes the Galbeta1,3GalNAc on O-glycans of glycoproteins (core1 O-glycans) as an acceptor substrate. Members of this family belong to glycosyltransferase family29 (GT29).


Pssm-ID: 467708  Cd Length: 280  Bit Score: 58.35  E-value: 1.21e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248  84 GLLEGYISVLEHKPLkMHCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILR 163
Cdd:cd23980    64 QVVPGNVDPLLEKRL-VSCRRCAVVGNSGNLKESYYGPQIDSHDFVLRMNKAPTEGFEADVGSKTTHHFVYPESFRELAQ 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 164 NRNELL------------------NMSHGAVFIfwgPSSYMRRDGKGLVYNnlqlmnqilPQLKVYMISRhkMLQfddlf 225
Cdd:cd23980   143 NVSMILvpfktldlewvisatttgTISHTYVPV---PRKIKVKKEKILIYH---------PAFIKYVFDR--WLQ----- 203

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1720787248 226 kretGKDRkisntWLSTGWFTMTIALELCERINVYG 261
Cdd:cd23980   204 ----GHGR-----YPSTGILSVIFSLHVCDEVDLYG 230
GT29_ST3GAL2 cd23979
beta-galactoside alpha-2,3-sialyltransferase 2; ST3GAL family transfer sialic acid from ...
 101-261 1.64e-09

beta-galactoside alpha-2,3-sialyltransferase 2; ST3GAL family transfer sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL2 preferentially utilizes the Galbeta1,3GalNAc on glycolipids as an acceptor substrate. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467707  Cd Length: 279  Bit Score: 57.96  E-value: 1.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 101 HCKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILRNRNELL----------- 169
Cdd:cd23979    79 RCRRCAVVGNSGNLRGSGYGKDIDGHDFIMRMNQAPTVGFEADVGSRTTHHFMYPESAKNLPANVSFVLvpfktldllwi 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 170 --NMSHGAVFIFWGP-SSYMRRDG-KGLVYNnlqlmnqilPQLKVYMisrhkmlqfDDLFKRETGKdrkisntWLSTGWF 245
Cdd:cd23979   159 tsALSTGQIRFTYAPvKQFLRVDKdKVQIYN---------PAFFKYI---------HDRWTEHHGR-------YPSTGML 213

                         170
                  ....*....|....*.
gi 1720787248 246 TMTIALELCERINVYG 261
Cdd:cd23979   214 VLFFALHVCDEVNVYG 229
GT29_ST6GALNAC2 cd23972
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; ST6GalNAc family members are ...
 102-149 7.76e-08

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc2 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467700  Cd Length: 308  Bit Score: 53.29  E-value: 7.76e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1720787248 102 CKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTS 149
Cdd:cd23972    82 CIRCAVVGNGGILNGSRQGRAIDAHDYVFRLNGAVIKGFEEDVGTKTS 129
GT29_ST8SIA5 cd23990
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 5; alpha-N-acetylneuraminide alpha-2, ...
 103-286 1.53e-07

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 5; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 5 (also known as alpha-2,8-sialyltransferase 8E) is involved in the biosynthesis of gangliosides, such as GD1c, GT1a, GQ1b, and GT3. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The ST8Sia family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467718  Cd Length: 273  Bit Score: 52.15  E-value: 1.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 103 KSCALVTSSGHLLGSRQGHRIDESECVIRMNDAP-TRGYGTDVGNKTSLRVIAHSSI----QRILRNRN---ELLNMSHG 174
Cdd:cd23990    65 KKCAVVGNGGILKNSKCGREIDSADFVFRCNLPPiSEKYVRDVGVKTDVVTINPSIIterfHKLEKWRRpfyEVLQVYEN 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720787248 175 AVFIFwgPSSYMRRDgKGLVYNNLQLMNQILPQLKVYMISRHKMLQFDDLFKRETGKDRKISntwlsTGWFTMTIALELC 254
Cdd:cd23990   145 ASVVL--PAFYNTRN-TDVSIRVKYVLDDFESQQAVYYFHPQYLLNVSRFWLRQGVRAKRIS-----SGLMLVTAALELC 216

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1720787248 255 ERINVYGMVPpdFCRDPNHLSVPYHYYEPLGP 286
Cdd:cd23990   217 EEVHLYGFWA--FPMNPSGIFITHHYYDNVKP 246
GT29_ST6GALNAC2L cd23974
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2-like; ST6GalNAc family members are ...
 102-164 4.46e-06

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2-like; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467702  Cd Length: 309  Bit Score: 47.83  E-value: 4.46e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720787248 102 CKSCALVTSSGHLLGSRQGHRIDESECVIRMNDAPTRGYGTDVGNKTSLRVIAHSSIQRILRN 164
Cdd:cd23974    84 CIRCAVVGNGGILNGSRMGAEIDGHDYVFRVNGAITKGFEKDVGRRTSFYTFSTNTLMNSLRA 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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