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Conserved domains on  [gi|1444542519|ref|XP_025948084|]
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aspartyl/asparaginyl beta-hydroxylase-like [Apteryx rowi]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Asp_Arg_Hydrox pfam05118
Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases ...
 415-569 2.25e-75

Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyze oxidative reactions in a range of metabolic processes. Proline 3-hydroxylase hydroxylates proline at position 3, the first of a 2-OG oxygenase catalysing oxidation of a free alpha-amino acid. The structure of proline 3-hydroxylase contains the conserved motifs present in other 2-OG oxygenases including a jelly roll strand core and residues binding iron and 2-oxoglutarate, consistent with divergent evolution within the extended family. This family represent the arginine, asparagine and proline hydroxylases. The aspartyl/asparaginyl beta-hydroxylase (EC:1.14.11.16) specifically hydroxylates one aspartic or asparagine residue in certain epidermal growth factor-like domains of a number of proteins.


:

Pssm-ID: 461552  Cd Length: 157  Bit Score: 236.39  E-value: 2.25e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 415 EKNWKLIRDEGLAVMDKKRSLFLPEDENLREKGD--WSQFTLWQQGRKNENACKGAPKTCALLERFP-EATGCRRGQIKY 491
Cdd:pfam05118   1 EANWQVIRDELLALLKQEEGLPPYEEEALDDFGDigWKTFYLYAYGARLPENCALCPKTAALLEQPGvKASGCPRGQAMF 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1444542519 492 SVMHPGTHVWPHTGPTNCRLRMHLGLVIPkEGCRIRCAQENRTWEEGKVLIFDDSFEHEVWQDAENYRLIFIVDVWHP 569
Cdd:pfam05118  81 SRLQPGTHIPPHRGPTNGRLRCHLGLVVP-PGCRIRVGGETRTWREGECLLFDDSFEHEAWNETDEPRVVLLVDVWRP 157
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 163-384 9.78e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 86.71  E-value: 9.78e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 163 KTIKAELDAAEKLRKKGKVEEALRAFEALVNQYPQSPRARYGkaqseddLAEKMRSNEMLQQAINTYDEVAGL-PNVPSD 241
Cdd:COG2956    40 ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLE-------LAQDYLKAGLLDRAEELLEKLLELdPDDAEA 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 242 LMKLslkreADRQQFLGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFI 321
Cdd:COG2956   113 LRLL-----AEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAEL 187

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1444542519 322 LKAENKIAESIPYLKEGLESgDPgtNDGRFYFHLGDALQRIGD-KEAYKWYELGYQRGHFASVW 384
Cdd:COG2956   188 YLEQGDYEEAIAALERALEQ-DP--DYLPALPRLAELYEKLGDpEEALELLRKALELDPSDDLL 248
 
Name Accession Description Interval E-value
Asp_Arg_Hydrox pfam05118
Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases ...
 415-569 2.25e-75

Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyze oxidative reactions in a range of metabolic processes. Proline 3-hydroxylase hydroxylates proline at position 3, the first of a 2-OG oxygenase catalysing oxidation of a free alpha-amino acid. The structure of proline 3-hydroxylase contains the conserved motifs present in other 2-OG oxygenases including a jelly roll strand core and residues binding iron and 2-oxoglutarate, consistent with divergent evolution within the extended family. This family represent the arginine, asparagine and proline hydroxylases. The aspartyl/asparaginyl beta-hydroxylase (EC:1.14.11.16) specifically hydroxylates one aspartic or asparagine residue in certain epidermal growth factor-like domains of a number of proteins.


Pssm-ID: 461552  Cd Length: 157  Bit Score: 236.39  E-value: 2.25e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 415 EKNWKLIRDEGLAVMDKKRSLFLPEDENLREKGD--WSQFTLWQQGRKNENACKGAPKTCALLERFP-EATGCRRGQIKY 491
Cdd:pfam05118   1 EANWQVIRDELLALLKQEEGLPPYEEEALDDFGDigWKTFYLYAYGARLPENCALCPKTAALLEQPGvKASGCPRGQAMF 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1444542519 492 SVMHPGTHVWPHTGPTNCRLRMHLGLVIPkEGCRIRCAQENRTWEEGKVLIFDDSFEHEVWQDAENYRLIFIVDVWHP 569
Cdd:pfam05118  81 SRLQPGTHIPPHRGPTNGRLRCHLGLVVP-PGCRIRVGGETRTWREGECLLFDDSFEHEAWNETDEPRVVLLVDVWRP 157
LpxO2 COG3555
Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, ...
 411-576 3.93e-57

Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442776  Cd Length: 220  Bit Score: 191.24  E-value: 3.93e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 411 VKSLEKNWKLIRDEGLAVMDKKRSL-----FLPEDENLREKGDWSQFTLWQQGRKNENACKGAPKTCALLERFPeatgcr 485
Cdd:COG3555    20 LAELEANWPTIRAELLALLAEIEALppyhdISFDQANIFFDRGWKRFYLYWYGERHPSNCALCPKTAALLEQIP------ 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 486 rgQIK---YSVMHPGTHVWPHTGPTNCRLRMHLGLVIP-KEGCRIRCAQENRTWEEGKVLIFDDSFEHEVWQDAENYRLI 561
Cdd:COG3555    94 --GVKaamFSILPPGKHIPPHRGPYNGRLRYHLGLIVPnDDRCRIRVDGETYSWREGEAVLFDDTYEHEAWNDTDETRVV 171

                         170
                  ....*....|....*
gi 1444542519 562 FIVDVWHPELTAQQR 576
Cdd:COG3555   172 LFCDVWRPMLSPWER 186
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 163-384 9.78e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 86.71  E-value: 9.78e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 163 KTIKAELDAAEKLRKKGKVEEALRAFEALVNQYPQSPRARYGkaqseddLAEKMRSNEMLQQAINTYDEVAGL-PNVPSD 241
Cdd:COG2956    40 ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLE-------LAQDYLKAGLLDRAEELLEKLLELdPDDAEA 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 242 LMKLslkreADRQQFLGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFI 321
Cdd:COG2956   113 LRLL-----AEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAEL 187

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1444542519 322 LKAENKIAESIPYLKEGLESgDPgtNDGRFYFHLGDALQRIGD-KEAYKWYELGYQRGHFASVW 384
Cdd:COG2956   188 YLEQGDYEEAIAALERALEQ-DP--DYLPALPRLAELYEKLGDpEEALELLRKALELDPSDDLL 248
tol_pal_ybgF TIGR02795
tol-pal system protein YbgF; Members of this protein family are the product of one of seven ...
 166-279 2.75e-07

tol-pal system protein YbgF; Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.


Pssm-ID: 188247 [Multi-domain]  Cd Length: 117  Bit Score: 49.20  E-value: 2.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 166 KAELDAAEKLRKKGKVEEALRAFEALVNQYPQSPR---ARYGKAQSEDDLAEKMRSNEMLQQAINTYDEVaglPNVPSDL 242
Cdd:TIGR02795   1 EAYYDAALLVLKAGDYADAIQAFQAFLKKYPKSTYapnAHYWLGEAYYAQGDYADAAKAFLAVVKKYPKS---PKAPDAL 77

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1444542519 243 MKLslkreADRQQFLGRMRGSLVTLQKLVHLFPSDTS 279
Cdd:TIGR02795  78 LKL-----GMSLQELGDKEKAKATLQQVIKRYPGSSA 109
YfiO pfam13525
Outer membrane lipoprotein; This outer membrane lipoprotein carries a TPR-like region towards ...
 177-284 5.98e-03

Outer membrane lipoprotein; This outer membrane lipoprotein carries a TPR-like region towards its N-terminal. YfiO in E.coli is one of three outer membrane lipoproteins that form a multicomponent YaeT complex in the outer membrane of Gram-negative bacteria that is involved in the targeting and folding of beta-barrel outer membrane proteins. YfiO is the only essential lipoprotein component of the complex. It is required for the proper assembly and/or targeting of outer membrane proteins to the outer membrane. Through its interactions with NlpB it maintains the functional integrity of the YaeT complex.


Pssm-ID: 433282 [Multi-domain]  Cd Length: 200  Bit Score: 38.46  E-value: 5.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 177 KKGKVEEALRAFEALVNQYPQSPRArygkAQSEDDLAEKMRSNEMLQQAINTYDEVAGL----PNVP--------SDLMK 244
Cdd:pfam13525  16 QKGDYGDAIKKLEALDNRYPFSPYA----EQAQLDLIYAYYKDADYADALAAAERFLRLypthPNIDyvyymrglSNFAQ 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1444542519 245 LSLKREADRQQflGRMRGSLVTLQKLVHLFPsDTSFKNDL 284
Cdd:pfam13525  92 DRDFFRSDRDP--ESARQAFEDFATLIRKYP-DSEYATDA 128
 
Name Accession Description Interval E-value
Asp_Arg_Hydrox pfam05118
Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases ...
 415-569 2.25e-75

Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyze oxidative reactions in a range of metabolic processes. Proline 3-hydroxylase hydroxylates proline at position 3, the first of a 2-OG oxygenase catalysing oxidation of a free alpha-amino acid. The structure of proline 3-hydroxylase contains the conserved motifs present in other 2-OG oxygenases including a jelly roll strand core and residues binding iron and 2-oxoglutarate, consistent with divergent evolution within the extended family. This family represent the arginine, asparagine and proline hydroxylases. The aspartyl/asparaginyl beta-hydroxylase (EC:1.14.11.16) specifically hydroxylates one aspartic or asparagine residue in certain epidermal growth factor-like domains of a number of proteins.


Pssm-ID: 461552  Cd Length: 157  Bit Score: 236.39  E-value: 2.25e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 415 EKNWKLIRDEGLAVMDKKRSLFLPEDENLREKGD--WSQFTLWQQGRKNENACKGAPKTCALLERFP-EATGCRRGQIKY 491
Cdd:pfam05118   1 EANWQVIRDELLALLKQEEGLPPYEEEALDDFGDigWKTFYLYAYGARLPENCALCPKTAALLEQPGvKASGCPRGQAMF 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1444542519 492 SVMHPGTHVWPHTGPTNCRLRMHLGLVIPkEGCRIRCAQENRTWEEGKVLIFDDSFEHEVWQDAENYRLIFIVDVWHP 569
Cdd:pfam05118  81 SRLQPGTHIPPHRGPTNGRLRCHLGLVVP-PGCRIRVGGETRTWREGECLLFDDSFEHEAWNETDEPRVVLLVDVWRP 157
LpxO2 COG3555
Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, ...
 411-576 3.93e-57

Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442776  Cd Length: 220  Bit Score: 191.24  E-value: 3.93e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 411 VKSLEKNWKLIRDEGLAVMDKKRSL-----FLPEDENLREKGDWSQFTLWQQGRKNENACKGAPKTCALLERFPeatgcr 485
Cdd:COG3555    20 LAELEANWPTIRAELLALLAEIEALppyhdISFDQANIFFDRGWKRFYLYWYGERHPSNCALCPKTAALLEQIP------ 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 486 rgQIK---YSVMHPGTHVWPHTGPTNCRLRMHLGLVIP-KEGCRIRCAQENRTWEEGKVLIFDDSFEHEVWQDAENYRLI 561
Cdd:COG3555    94 --GVKaamFSILPPGKHIPPHRGPYNGRLRYHLGLIVPnDDRCRIRVDGETYSWREGEAVLFDDTYEHEAWNDTDETRVV 171

                         170
                  ....*....|....*
gi 1444542519 562 FIVDVWHPELTAQQR 576
Cdd:COG3555   172 LFCDVWRPMLSPWER 186
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 163-384 9.78e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 86.71  E-value: 9.78e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 163 KTIKAELDAAEKLRKKGKVEEALRAFEALVNQYPQSPRARYGkaqseddLAEKMRSNEMLQQAINTYDEVAGL-PNVPSD 241
Cdd:COG2956    40 ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLE-------LAQDYLKAGLLDRAEELLEKLLELdPDDAEA 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 242 LMKLslkreADRQQFLGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFI 321
Cdd:COG2956   113 LRLL-----AEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAEL 187

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1444542519 322 LKAENKIAESIPYLKEGLESgDPgtNDGRFYFHLGDALQRIGD-KEAYKWYELGYQRGHFASVW 384
Cdd:COG2956   188 YLEQGDYEEAIAALERALEQ-DP--DYLPALPRLAELYEKLGDpEEALELLRKALELDPSDDLL 248
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 167-376 2.36e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 69.64  E-value: 2.36e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 167 AELDAAEKLRKKGKVEEALRAFEALVNQYPQSPRARYGKAQSEDDLAEKMRSNEMLQQAINTYDEVAGlpnvPSDLMKLS 246
Cdd:COG3914     5 ALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAA----ALLLLAAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 247 LKREADRQQFLGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAEN 326
Cdd:COG3914    81 LELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1444542519 327 KIAESIPYLKEGLESgDPgtNDGRFYFHLGDALQRIGD-KEAYKWYELGYQ 376
Cdd:COG3914   161 RLEEAIAALRRALEL-DP--DNAEALNNLGNALQDLGRlEEAIAAYRRALE 208
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
175-340 1.02e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.33  E-value: 1.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 175 LRKKGKVEEALRAFEALVNQYPQSPRARYGKAQSEDDLaekmrsnEMLQQAINTYDEVAGL-PNVPSDLMKLslkreADR 253
Cdd:COG0457    18 YRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRL-------GRYEEALADYEQALELdPDDAEALNNL-----GLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 254 QQFLGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAESIP 333
Cdd:COG0457    86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165


                  ....*..
gi 1444542519 334 YLKEGLE 340
Cdd:COG0457   166 LLEKLEA 172
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 167-340 1.37e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.44  E-value: 1.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 167 AELDAAEKLRKKGKVEEALRAFEALVNQYPQSPRARYGKAQSeddlaekmrsnemlqqaintydevaglpnvpsdlmkls 246
Cdd:COG4783     6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEI-------------------------------------- 47

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 247 lkreadrQQFLGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAEN 326
Cdd:COG4783    48 -------LLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALG 120

                         170
                  ....*....|....
gi 1444542519 327 KIAESIPYLKEGLE 340
Cdd:COG4783   121 RPDEAIAALEKALE 134
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
257-372 3.79e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 60.41  E-value: 3.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 257 LGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAESIPYLK 336
Cdd:COG0457    21 LGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYD 100

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1444542519 337 EGLESgDPgtNDGRFYFHLGDALQRIGD-KEAYKWYE 372
Cdd:COG0457   101 KALEL-DP--DDAEALYNLGLALLELGRyDEAIEAYE 134
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 257-341 5.24e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.35  E-value: 5.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 257 LGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAESIPYLK 336
Cdd:COG5010    67 LGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQ 146


                  ....*
gi 1444542519 337 EGLES 341
Cdd:COG5010   147 RALGT 151
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 264-372 1.27e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.47  E-value: 1.27e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 264 LVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAESIPYLKEGLESgD 343
Cdd:COG4235     3 IARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL-D 81

                          90       100       110
                  ....*....|....*....|....*....|
gi 1444542519 344 PgtNDGRFYFHLGDALQRIGD-KEAYKWYE 372
Cdd:COG4235    82 P--DNPEALYLLGLAAFQQGDyAEAIAAWQ 109
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 257-347 1.19e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.77  E-value: 1.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 257 LGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAESIPYLK 336
Cdd:COG4235    30 LGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQ 109

                          90
                  ....*....|.
gi 1444542519 337 EGLESGDPGTN 347
Cdd:COG4235   110 KLLALLPADAP 120
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
288-372 1.83e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.40  E-value: 1.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 288 YLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAESIPYlKEGLESgDPgtNDGRFYFHLGDALQRIGD-KE 366
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL-DP--NNAEALLNLAELLLELGDyDE 77


                  ....*.
gi 1444542519 367 AYKWYE 372
Cdd:COG3063    78 ALAYLE 83
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
271-372 2.02e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.32  E-value: 2.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 271 VHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAESIPYLKEGLESgDPgtNDGR 350
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL-DP--DDAE 77

                          90       100
                  ....*....|....*....|...
gi 1444542519 351 FYFHLGDALQRIGD-KEAYKWYE 372
Cdd:COG0457    78 ALNNLGLALQALGRyEEALEDYD 100
tol_pal_ybgF TIGR02795
tol-pal system protein YbgF; Members of this protein family are the product of one of seven ...
 166-279 2.75e-07

tol-pal system protein YbgF; Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.


Pssm-ID: 188247 [Multi-domain]  Cd Length: 117  Bit Score: 49.20  E-value: 2.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 166 KAELDAAEKLRKKGKVEEALRAFEALVNQYPQSPR---ARYGKAQSEDDLAEKMRSNEMLQQAINTYDEVaglPNVPSDL 242
Cdd:TIGR02795   1 EAYYDAALLVLKAGDYADAIQAFQAFLKKYPKSTYapnAHYWLGEAYYAQGDYADAAKAFLAVVKKYPKS---PKAPDAL 77

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1444542519 243 MKLslkreADRQQFLGRMRGSLVTLQKLVHLFPSDTS 279
Cdd:TIGR02795  78 LKL-----GMSLQELGDKEKAKATLQQVIKRYPGSSA 109
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 288-372 3.41e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 50.34  E-value: 3.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 288 YLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAESIPYLKEGLESgDPgtNDGRFYFHLGDALQRIGD-KE 366
Cdd:COG5010    64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL-SP--DNPNAYSNLAALLLSLGQdDE 140


                  ....*.
gi 1444542519 367 AYKWYE 372
Cdd:COG5010   141 AKAALQ 146
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 162-340 1.25e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.11  E-value: 1.25e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 162 DKTIKAELDAAEKLRKKGKVEEALRAFEALVNQYPQSPRARYGkaqseddLAEKMRSNEMLQQAINTYDEVAGL-PNVPS 240
Cdd:COG2956   107 PDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCE-------LAELYLEQGDYDEAIEALEKALKLdPDCAR 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 241 DLMKLslkreADRQQFLGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDgFAKVHYGF 320
Cdd:COG2956   180 ALLLL-----AELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALAD 253

                         170       180
                  ....*....|....*....|
gi 1444542519 321 ILKAENKIAESIPYLKEGLE 340
Cdd:COG2956   254 LLERKEGLEAALALLERQLR 273
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 165-351 5.89e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.31  E-value: 5.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 165 IKAELDAAEKLRKKGKVEEALRAFEALVNQYPQSPRARYGKAQSE----------DDLAEKMRSN--------------- 219
Cdd:TIGR02917 227 IAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDfqkknyedarETLQDALKSApeylpalllagasey 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 220 -----EMLQQAINTYdeVAGLPNVPsdlmkLSLKREADRQQFLGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDN 294
Cdd:TIGR02917 307 qlgnlEQAYQYLNQI--LKYAPNSH-----QARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDF 379

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1444542519 295 SNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAESIPYLKEGLESGDPGTNDGRF 351
Cdd:TIGR02917 380 EKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLL 436
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 174-276 8.25e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.98  E-value: 8.25e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 174 KLRKKGKVEEALRAFEALVNQYPQS---PRARYGKAQSEDDLAEKMRSNEMLQQAINTYDEVaglPNVPSDLMKLslkre 250
Cdd:COG1729     2 ALLKAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDS---PKAPDALLKL----- 73

                          90       100
                  ....*....|....*....|....*.
gi 1444542519 251 ADRQQFLGRMRGSLVTLQKLVHLFPS 276
Cdd:COG1729    74 GLSYLELGDYDKARATLEELIKKYPD 99
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
257-340 8.54e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.39  E-value: 8.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 257 LGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKvYEEVLSLAPNDGFAKVHYGFILKAENKIAESIPYLK 336
Cdd:COG3063     5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83


                  ....
gi 1444542519 337 EGLE 340
Cdd:COG3063    84 RALE 87
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 172-229 3.17e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.44  E-value: 3.17e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1444542519 172 AEKLRKKGKVEEALRAFEALVNQYPQS---PRARYGKAQSEDDLAEKMRSNEMLQQAINTY 229
Cdd:COG1729    37 GEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLELGDYDKARATLEELIKKY 97
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 171-339 1.65e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 171 AAEKLRKKGKVEEALRAFEALVNQYPQSPRARYGKAQSEDDLAEKMRSNEMLQQAINTYDEvagLPNVPSDLMKLSLKRe 250
Cdd:TIGR02917 369 LGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPE---LGRADLLLILSYLRS- 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 251 adrqqflGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAE 330
Cdd:TIGR02917 445 -------GQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDD 517


                  ....*....
gi 1444542519 331 SIPYLKEGL 339
Cdd:TIGR02917 518 AIQRFEKVL 526
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
175-311 2.69e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.07  E-value: 2.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 175 LRKKGKVEEALRAFEALVNQYPQSPRARYGKAQSEDDLAEkmrsnemLQQAINTYDEVAGL-PNVPSDLMKLslkreADR 253
Cdd:COG0457    52 YLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGR-------YEEALEDYDKALELdPDDAEALYNL-----GLA 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1444542519 254 QQFLGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPND 311
Cdd:COG0457   120 LLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAA 177
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 176-340 4.09e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.53  E-value: 4.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 176 RKKGKVEEALRAFEALVNQYPQSPRARYGKAqsedDLAEKMRSNEMlqqAINTYDEVAGLPnvPSDL-MKLSLKREADRQ 254
Cdd:TIGR02917 510 IQEGNPDDAIQRFEKVLTIDPKNLRAILALA----GLYLRTGNEEE---AVAWLEKAAELN--PQEIePALALAQYYLGK 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 255 qflGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAESIPY 334
Cdd:TIGR02917 581 ---GQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITS 657


                  ....*.
gi 1444542519 335 LKEGLE 340
Cdd:TIGR02917 658 LKRALE 663
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 162-348 4.46e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 4.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 162 DKTIKAELDAAEKLRKKGKVEEALRAFEALVNQYPQSPRARY--GKAQSED-DL--AEKmrsnEMLQQAINTYDEVAGLP 236
Cdd:TIGR02917  19 DQSPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFllGKIYLALgDYaaAEK----ELRKALSLGYPKNQVLP 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 237 nvpsDLMKLSLKREADrqqflgrmrgslvtlQKLVHLFPSDTSFKND--------LGVGYLLTGDNSNAKKVYEEVLSLA 308
Cdd:TIGR02917  95 ----LLARAYLLQGKF---------------QQVLDELPGKTLLDDEgaaellalRGLAYLGLGQLELAQKSYEQALAID 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1444542519 309 PNDGFAKVHYGFILKAENKIAESIPYLKEGLeSGDPGTND 348
Cdd:TIGR02917 156 PRSLYAKLGLAQLALAENRFDEARALIDEVL-TADPGNVD 194
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 178-368 1.94e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 1.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 178 KGKVEEALRAFEALVNQYPQSPRARYGKAQSeddlaeKMRSNEmLQQAINTYDEVAGL--PNVPSDLMKlslkreADRQQ 255
Cdd:TIGR02917 138 LGQLELAQKSYEQALAIDPRSLYAKLGLAQL------ALAENR-FDEARALIDEVLTAdpGNVDALLLK------GDLLL 204

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 256 FLGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAkvHYgfiLKA-----ENKIAE 330
Cdd:TIGR02917 205 SLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLA--HY---LKAlvdfqKKNYED 279

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1444542519 331 SIPYLKEGLESgDPGTNDGRFY-----FHLGD---ALQRIGDKEAY 368
Cdd:TIGR02917 280 ARETLQDALKS-APEYLPALLLagaseYQLGNleqAYQYLNQILKY 324
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 167-309 2.45e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.79  E-value: 2.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 167 AELDAAEKLRKKGKVEEALRAFEALVNQYPQSPRARYGKAQSEDDLAEKMRSNemLQQAINTYDEVAGL-PNVPSDLMKL 245
Cdd:COG5010    17 LTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGD--FEESLALLEQALQLdPNNPELYYNL 94

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1444542519 246 slkreADRQQFLGRMRGSLVTLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAP 309
Cdd:COG5010    95 -----ALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 288-372 3.69e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 3.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 288 YLLTGDNSNAKKVYEEVLSLAPNDGFA-KVHY--GFILKAENKIAESIPYLKEGLESGDPGTNDGRFYFHLGDALQRIGD 364
Cdd:COG1729     3 LLKAGDYDEAIAAFKAFLKRYPNSPLApDALYwlGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELGD 82


                  ....*....
gi 1444542519 365 KE-AYKWYE 372
Cdd:COG1729    83 YDkARATLE 91
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
209-418 4.23e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.13  E-value: 4.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 209 EDDLAEKMRSNEMLQQAINtYDEVAGLPNVPSDLMKLSLKREADRQQFLGRMRGSLVTLQKLvhlfPSDTSFKNDLGVGY 288
Cdd:COG4785     9 LLALALAAAAASKAAILLA-ALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALAL----PDLAQLYYERGVAY 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 289 LLTGDNSNAKKVYEEVLSLAPndGFAKVHY--GFILKAENKIAESIPYLKEGLESgDPgtNDGRFYFHLGDALQRIGD-K 365
Cdd:COG4785    84 DSLGDYDLAIADFDQALELDP--DLAEAYNnrGLAYLLLGDYDAALEDFDRALEL-DP--DYAYAYLNRGIALYYLGRyE 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1444542519 366 EAYKWYELGYQRG---HFASVWQrslynvkglkaqpWWTARETGYTELVKSLEKNW 418
Cdd:COG4785   159 LAIADLEKALELDpndPERALWL-------------YLAERKLDPEKALALLLEDW 201
OM_YfiO TIGR03302
outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a ...
 170-231 4.63e-03

outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274513 [Multi-domain]  Cd Length: 235  Bit Score: 39.07  E-value: 4.63e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1444542519 170 DAAEKLRKKGKVEEALRAFEALVNQYPQSPRARygkaQSEDDLAEKMRSNEMLQQAINTYDE 231
Cdd:TIGR03302  38 EEAKEALDSGDYTEAIKYFEALESRYPFSPYAE----QAQLDLAYAYYKSGDYAEAIAAADR 95
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 266-372 5.64e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 5.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 266 TLQKLVHLFPSDTSFKNDLGVGYLLTGDNSNAKKVYEEVLSLAPNDGFAKVHYGFILKAENKIAESIPYLKEGLESGDpg 345
Cdd:COG2956    30 LLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDP-- 107

                          90       100
                  ....*....|....*....|....*...
gi 1444542519 346 tNDGRFYFHLGDALQRIGD-KEAYKWYE 372
Cdd:COG2956   108 -DDAEALRLLAEIYEQEGDwEKAIEVLE 134
YfiO pfam13525
Outer membrane lipoprotein; This outer membrane lipoprotein carries a TPR-like region towards ...
 177-284 5.98e-03

Outer membrane lipoprotein; This outer membrane lipoprotein carries a TPR-like region towards its N-terminal. YfiO in E.coli is one of three outer membrane lipoproteins that form a multicomponent YaeT complex in the outer membrane of Gram-negative bacteria that is involved in the targeting and folding of beta-barrel outer membrane proteins. YfiO is the only essential lipoprotein component of the complex. It is required for the proper assembly and/or targeting of outer membrane proteins to the outer membrane. Through its interactions with NlpB it maintains the functional integrity of the YaeT complex.


Pssm-ID: 433282 [Multi-domain]  Cd Length: 200  Bit Score: 38.46  E-value: 5.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444542519 177 KKGKVEEALRAFEALVNQYPQSPRArygkAQSEDDLAEKMRSNEMLQQAINTYDEVAGL----PNVP--------SDLMK 244
Cdd:pfam13525  16 QKGDYGDAIKKLEALDNRYPFSPYA----EQAQLDLIYAYYKDADYADALAAAERFLRLypthPNIDyvyymrglSNFAQ 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1444542519 245 LSLKREADRQQflGRMRGSLVTLQKLVHLFPsDTSFKNDL 284
Cdd:pfam13525  92 DRDFFRSDRDP--ESARQAFEDFATLIRKYP-DSEYATDA 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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