NCBI Conserved Domain Search

Conserved domains on [gi|1370521309|ref|XP_024308171|]

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muscleblind-like protein 3 isoform X2 [Homo sapiens]

Protein Classification

zinc finger CCCH domain-containing protein( domain architecture ID 10646956)

zinc finger CCCH domain-containing protein similar to Homo sapiens Muscleblind-like proteins

CATH: 4.10.1000.10

Gene Ontology: GO:0046872|GO:0003676

PubMed: 12665246|27990022

SCOP: 3001741

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

ZnF_C3H1

smart00356

zinc finger;

132-158

2.96e-05

zinc finger;

Pssm-ID: 214632 [Multi-domain] Cd Length: 27 Bit Score: 40.31 E-value: 2.96e-05

                           10        20
                   ....*....|....*....|....*..
gi 1370521309  132 SDKLEVCREFQRGNCTRGENdCRYAHP 158
Cdd:smart00356   1 KYKTELCKFFKRGYCPRGDR-CKFAHP 26

Name

Accession

Description

Interval

E-value

ZnF_C3H1

smart00356

zinc finger;

132-158

2.96e-05

zinc finger;

Pssm-ID: 214632 [Multi-domain] Cd Length: 27 Bit Score: 40.31 E-value: 2.96e-05

                           10        20
                   ....*....|....*....|....*..
gi 1370521309  132 SDKLEVCREFQRGNCTRGENdCRYAHP 158
Cdd:smart00356   1 KYKTELCKFFKRGYCPRGDR-CKFAHP 26

zf_CCCH_4

pfam18345

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...

138-157

1.03e-03

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.

Pssm-ID: 465719 [Multi-domain] Cd Length: 19 Bit Score: 35.86 E-value: 1.03e-03

                          10        20
                  ....*....|....*....|
gi 1370521309 138 CREFQRGNCTRGENdCRYAH 157
Cdd:pfam18345   1 CKFFLKGRCRYGDK-CRFAH 19

Name

Accession

Description

Interval

E-value

ZnF_C3H1

smart00356

zinc finger;

132-158

2.96e-05

zinc finger;

Pssm-ID: 214632 [Multi-domain] Cd Length: 27 Bit Score: 40.31 E-value: 2.96e-05

                           10        20
                   ....*....|....*....|....*..
gi 1370521309  132 SDKLEVCREFQRGNCTRGENdCRYAHP 158
Cdd:smart00356   1 KYKTELCKFFKRGYCPRGDR-CKFAHP 26

zf_CCCH_4

pfam18345

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...

138-157

1.03e-03

Pssm-ID: 465719 [Multi-domain] Cd Length: 19 Bit Score: 35.86 E-value: 1.03e-03

                          10        20
                  ....*....|....*....|
gi 1370521309 138 CREFQRGNCTRGENdCRYAH 157
Cdd:pfam18345   1 CKFFLKGRCRYGDK-CRFAH 19

zf-CCCH_4

pfam18044

CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and ...

137-158

1.21e-03

CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and one histidine to coordinate the zinc ion. This domain is found in a wide variety of proteins such as E3 ligases.

Pssm-ID: 465626 Cd Length: 22 Bit Score: 35.64 E-value: 1.21e-03

                          10        20
                  ....*....|....*....|..
gi 1370521309 137 VCREFQRGNCTRGENdCRYAHP 158
Cdd:pfam18044   2 LCRYFQKGGCRYGDN-CRFSHD 22

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01