|
Name |
Accession |
Description |
Interval |
E-value |
| DUF4482 |
pfam14818 |
Domain of unknown function (DUF4482); This family is found in eukaryotes, and is approximately ... |
1295-1418 |
2.37e-52 |
|
Domain of unknown function (DUF4482); This family is found in eukaryotes, and is approximately 140 amino acids in length. The family is found in association with pfam11365.
Pssm-ID: 464333 [Multi-domain] Cd Length: 138 Bit Score: 180.65 E-value: 2.37e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 1295 MDLRWQIHHSEKNWNREKVELLDRLDRDRQEWERQKKEFLWRIEQLQKENSPRR------------GGSFLCDQKDGNVR 1362
Cdd:pfam14818 1 MDLRWQLQHTEKNWHREKMELLDRFDRERQEWESQKKIMQKKIEQLQREVSLRRkinmnerakvidGEKFVPDQKESSSP 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2217316411 1363 PFPHQGSLRMPR--PVAMWPCADADSIPFEDRPLSKLKESDRCSASENLYLDALSLDD 1418
Cdd:pfam14818 81 PFPDSGQCEFPRmnHPGSLSKSDSDEESFLDEGNQKLKEQKRCKASENLFLDALSLDN 138
|
|
| SOGA |
pfam11365 |
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, ... |
527-621 |
1.96e-38 |
|
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, SOGA2, and SOGA3. SOGA1 regulates autophagy by playing a role in the reduction of glucose production in an adiponectin and insulin dependent manner.
Pssm-ID: 463264 [Multi-domain] Cd Length: 95 Bit Score: 138.97 E-value: 1.96e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 527 DSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANI 606
Cdd:pfam11365 1 SSAELRRQLQFVEEEAELLRRSLSEIEDHNKQLTNELNKYKSKYGPDESSLSDGEGGGSDSSREAELQEELKLARLQINE 80
|
90
....*....|....*
gi 2217316411 607 LGRKIVELEVENRGL 621
Cdd:pfam11365 81 LSGKVMKLQYENRVL 95
|
|
| SOGA |
pfam11365 |
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, ... |
656-748 |
4.61e-38 |
|
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, SOGA2, and SOGA3. SOGA1 regulates autophagy by playing a role in the reduction of glucose production in an adiponectin and insulin dependent manner.
Pssm-ID: 463264 [Multi-domain] Cd Length: 95 Bit Score: 138.20 E-value: 4.61e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 656 SSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPPREPGWLGEGASPGA--GGGAPLQEELKSARLQISE 733
Cdd:pfam11365 1 SSAELRRQLQFVEEEAELLRRSLSEIEDHNKQLTNELNKYKSKYGPDESSLSDGEGGGSdsSREAELQEELKLARLQINE 80
|
90
....*....|....*
gi 2217316411 734 LSGKVLKLQHENHAL 748
Cdd:pfam11365 81 LSGKVMKLQYENRVL 95
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
12-326 |
1.29e-14 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 80.37 E-value: 1.29e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 12 APDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFL----KDLHARPAAPGPAVP---------SSGRAPAPAAPRSP 78
Cdd:PHA03247 2563 APDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRApvddRGDPRGPAPPSPLPPdthapdpppPSPSPAANEPDPHP 2642
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 79 NLAGKAPPSPGSLAAPGRLSR----RSGGVPGAKDKPPpgagaraaggakaALGSRRAARvAPAEPLSRAGKPPGAEPPS 154
Cdd:PHA03247 2643 PPTVPPPERPRDDPAPGRVSRprraRRLGRAAQASSPP-------------QRPRRRAAR-PTVGSLTSLADPPPPPPTP 2708
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 155 AAAKgRKAKRGSRAPP----ARTVGPPTPAARIPAVTLAVTSVAGSPARCSRiSHTDSSSDLSDCPSEPLSDEQRLLPAA 230
Cdd:PHA03247 2709 EPAP-HALVSATPLPPgpaaARQASPALPAAPAPPAVPAGPATPGGPARPAR-PPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 231 SSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVS------GGFAGPGvaEDVRG 304
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPppslplGGSVAPG--GDVRR 2864
|
330 340
....*....|....*....|....
gi 2217316411 305 RSPPERPV--PGTPKEPSLGEQSR 326
Cdd:PHA03247 2865 RPPSRSPAakPAAPARPPVRRLAR 2888
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
353-682 |
1.98e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 69.70 E-value: 1.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 353 ELDELRAEMEEMRDSY---------LEEDVYQLQE----LRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIR 419
Cdd:TIGR02168 678 EIEELEEKIEELEEKIaelekalaeLRKELEELEEeleqLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 420 SLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKtfnq 499
Cdd:TIGR02168 758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI---- 833
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 500 qnggmerpgncrpatKTQRKLAPRRKDDSADLRCQLQFAKEEaflmrkkMAKLGREKDELEQELQKYKSLYGDVDSPLpt 579
Cdd:TIGR02168 834 ---------------AATERRLEDLEEQIEELSEDIESLAAE-------IEELEELIEELESELEALLNERASLEEAL-- 889
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 580 geaggppstreAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLEsstE 659
Cdd:TIGR02168 890 -----------ALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE---E 955
|
330 340
....*....|....*....|...
gi 2217316411 660 LRRHLQFVEEEAELLRRSISEIE 682
Cdd:TIGR02168 956 AEALENKIEDDEEEARRRLKRLE 978
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
7-316 |
1.83e-10 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 66.73 E-value: 1.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 7 PAGGGAPDAklqPPGQHHRHHHLHPVAERRRLHRAPSPA-RPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAP 85
Cdd:PHA03307 122 PPASPPPSP---APDLSEMLRPVGSPGPPPAASPPAAGAsPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTP 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 86 PSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSR-RAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKR 164
Cdd:PHA03307 199 PAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSEsSGCGWGPENECPLPRPAPITLPTRIWEASGWNGP 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 165 GSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDRE 244
Cdd:PHA03307 279 SSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPP 358
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217316411 245 PPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGP-----GVAEDVRGRSPPERPVPGTP 316
Cdd:PHA03307 359 PADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGrprpsPLDAGAASGAFYARYPLLTP 435
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
10-319 |
9.97e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 64.19 E-value: 9.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 10 GGAPDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPG 89
Cdd:PHA03247 2639 DPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSA 2718
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 90 SLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAAR---VAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGS 166
Cdd:PHA03247 2719 TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTagpPAPAPPAAPAAGPPRRLTRPAVASLSESRESL 2798
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 167 RAPPARTVGPPTPAARIPAVTLAVTSVAGSPArcsrishtdSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSsdREPP 246
Cdd:PHA03247 2799 PSPWDPADPPAAVLAPAAALPPAASPAGPLPP---------PTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVR--RRPP 2867
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217316411 247 RGAPTPSPAARGAPPGSPEPPALLAAPLAAGACP--GGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEP 319
Cdd:PHA03247 2868 SRSPAAKPAAPARPPVRRLARPAVSRSTESFALPpdQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP 2942
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
39-331 |
5.03e-09 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 61.73 E-value: 5.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 39 HRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLS--RRSGGVPGAKDKPPPGAG 116
Cdd:PHA03307 77 TEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEmlRPVGSPGPPPAASPPAAG 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 117 ARAAGGAKAALGSRRAARVAP-----AEPLSRAGKPPGAEPPSAAAKGRKAKRGS----RAPPARTVGPPTPAARIPAvt 187
Cdd:PHA03307 157 ASPAAVASDAASSRQAALPLSspeetARAPSSPPAEPPPSTPPAAASPRPPRRSSpisaSASSPAPAPGRSAADDAGA-- 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 188 lAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPP 267
Cdd:PHA03307 235 -SSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPR 313
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217316411 268 ALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSLGEQSRLVPAA 331
Cdd:PHA03307 314 ASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSS 377
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
8-330 |
1.04e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 61.11 E-value: 1.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 8 AGGGAPDAKLQPPGQHHRHHHLHPVAERRRlHRAPSPARPflkdlharPAAPGPAVPSSGRapapaaprspnlAGKAPPS 87
Cdd:PHA03247 2728 ARQASPALPAAPAPPAVPAGPATPGGPARP-ARPPTTAGP--------PAPAPPAAPAAGP------------PRRLTRP 2786
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 88 PGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPP--SAAAKGRKAKRG 165
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggSVAPGGDVRRRP 2866
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 166 -SRAPPARTVGPPTPAAR---IPAVTLAVTSVAGSPARCSRISHTDSssdlsdcPSEPLSDEQRLLPAASSDAEsgtgss 241
Cdd:PHA03247 2867 pSRSPAAKPAAPARPPVRrlaRPAVSRSTESFALPPDQPERPPQPQA-------PPPPQPQPQPPPPPQPQPPP------ 2933
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 242 drePPRGAPTPSPAARGAPPGSPEppallaaplAAGACPGGRSipsgvsgGFAGPGVAEDVRGRSPPERPVPGTPKEPSL 321
Cdd:PHA03247 2934 ---PPPPRPQPPLAPTTDPAGAGE---------PSGAVPQPWL-------GALVPGRVAVPRFRVPQPAPSREAPASSTP 2994
|
....*....
gi 2217316411 322 GEQSRLVPA 330
Cdd:PHA03247 2995 PLTGHSLSR 3003
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
352-568 |
1.88e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 59.93 E-value: 1.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 352 DELDELRAEMEEMRDSY--LEedvyQLQELRRELDRANKNCRILQYRLRKAEqkslkvAETGQVDGELIRSLEQDLKVAK 429
Cdd:COG4913 235 DDLERAHEALEDAREQIelLE----PIRELAERYAAARERLAELEYLRAALR------LWFAQRRLELLEAELEELRAEL 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 430 DvsvRLHHELKTVEEKRAKAEDENETLRQQMIEVE-ISKQALQNELERLKESSLKRRSTREMYKEKktfnQQNGGMERPG 508
Cdd:COG4913 305 A---RLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEAL----LAALGLPLPA 377
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 509 NcRPATKTQRKLAPRRKDDSADLRCQLQfakEEAFLMRKKMAKLGREKDELEQELQKYKS 568
Cdd:COG4913 378 S-AEEFAALRAEAAALLEALEEELEALE---EALAEAEAALRDLRRELRELEAEIASLER 433
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
353-568 |
2.53e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.30 E-value: 2.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 353 ELDELRAEMEEMRDsylEEDVYQ--LQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQ-------VDGELIRSLEQ 423
Cdd:TIGR02168 268 KLEELRLEVSELEE---EIEELQkeLYALANEISRLEQQKQILRERLANLERQLEELEAQLEeleskldELAEELAELEE 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 424 DLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQM-------IEVEISKQALQNELERLKE--SSLKRRSTRemykek 494
Cdd:TIGR02168 345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLetlrskvAQLELQIASLNNEIERLEArlERLEDRRER------ 418
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217316411 495 ktfNQQNGGMERPGNCRPATKTQRKLAPRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKS 568
Cdd:TIGR02168 419 ---LQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
350-688 |
2.82e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.01 E-value: 2.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRDSYLE--------EDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETgqvdGELIRSL 421
Cdd:COG4717 93 LQEELEELEEELEELEAELEElreeleklEKLLQLLPLYQELEALEAELAELPERLEELEERLEELREL----EEELEEL 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 422 EQDLKVAK--------DVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKE 493
Cdd:COG4717 169 EAELAELQeeleelleQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEA 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 494 KKTFNQQNGGMERPGNCRPATKTQRKLAPRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGR--EKDELEQ-ELQKYKSLY 570
Cdd:COG4717 249 RLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQAlpALEELEEeELEELLAAL 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 571 GdVDSPLPTGEAGGPPST-----------REAELKLRLKLVEEEANILG-----------RKIVELEVENRGLKAEMEDM 628
Cdd:COG4717 329 G-LPPDLSPEELLELLDRieelqellreaEELEEELQLEELEQEIAALLaeagvedeeelRAALEQAEEYQELKEELEEL 407
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316411 629 RGQQEREGPGRDHAPSIPTspfGDSLES-STELRRHLQFVEEEAELLRRSISEIEDHNRQL 688
Cdd:COG4717 408 EEQLEELLGELEELLEALD---EEELEEeLEELEEELEELEEELEELREELAELEAELEQL 465
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
351-734 |
5.25e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.54 E-value: 5.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 351 KDELDELRAEMEEMrDSYLEEDVYQLQELRRELDRANKNcRILQYRLRKAEQ----KSLKVAETG--QVDGElIRSLEQD 424
Cdd:TIGR02169 176 LEELEEVEENIERL-DLIIDEKRQQLERLRREREKAERY-QALLKEKREYEGyellKEKEALERQkeAIERQ-LASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 425 LkvaKDVSVRLHHELKTVEEKRAKAEDENEtlrqqmievEISKQAlQNELERLKESSLKRRSTREMYKEKKTFNQQNggm 504
Cdd:TIGR02169 253 L---EKLTEEISELEKRLEEIEQLLEELNK---------KIKDLG-EEEQLRVKEKIGELEAEIASLERSIAEKERE--- 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 505 erpgncrpatktQRKLAPRRKDDSADLRCQlqfaKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLptgeagG 584
Cdd:TIGR02169 317 ------------LEDAEERLAKLEAEIDKL----LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAEL------E 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 585 PPSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMedmrgqQEREGPGRDHAPSIPtspfgDSLESSTELrrhl 664
Cdd:TIGR02169 375 EVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL------QRLSEELADLNAAIA-----GIEAKINEL---- 439
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 665 qfvEEEAELLRRSISEIEDHNRQLTHELSKFKFEpprepgwlgegASPGAGGGAPLQEELKSARLQISEL 734
Cdd:TIGR02169 440 ---EEEKEDKALEIKKQEWKLEQLAADLSKYEQE-----------LYDLKEEYDRVEKELSKLQRELAEA 495
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
85-331 |
6.21e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.41 E-value: 6.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 85 PPSPGSLAAPGRLSRRSggVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPlsrAGKPPGAEPPSAAAKGRKAKR 164
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRS--VPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDD---RGDPRGPAPPSPLPPDTHAPD 2625
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 165 ---GSRAPPARTVGPPTPAARIPAvtlAVTSVAGSPARCSRISHTDSSSDlsdcPSEPLSDEQRLLPAASSDAESGTGSS 241
Cdd:PHA03247 2626 pppPSPSPAANEPDPHPPPTVPPP---ERPRDDPAPGRVSRPRRARRLGR----AAQASSPPQRPRRRAARPTVGSLTSL 2698
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 242 DREPPRGaPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSL 321
Cdd:PHA03247 2699 ADPPPPP-PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA 2777
|
250
....*....|
gi 2217316411 322 GEQSRLVPAA 331
Cdd:PHA03247 2778 GPPRRLTRPA 2787
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
7-264 |
8.40e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 57.55 E-value: 8.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 7 PAGGGAPDAKLQPP---GQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGK 83
Cdd:PRK07003 362 VTGGGAPGGGVPARvagAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDD 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 84 APPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAK 163
Cdd:PRK07003 442 AADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDA 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 164 RGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCS--RIShtdsssdlsdcpseplSDEQRLLPAASSDAESGTGSS 241
Cdd:PRK07003 522 PAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAgmRVS----------------SDRGARAAAAAKPAAAPAAAP 585
|
250 260
....*....|....*....|....
gi 2217316411 242 DREPPRGA-PTPSPAARGAPPGSP 264
Cdd:PRK07003 586 KPAAPRVAvQVPTPRARAATGDAP 609
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
370-1102 |
1.21e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 1.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 370 EEDVYQLQELRRELDRANKNCRI-----LQYRLRKAEQKSLKVAETGQVDGELIRSLEQdLKVAKDVSVRLHHELktvEE 444
Cdd:TIGR02168 185 RENLDRLEDILNELERQLKSLERqaekaERYKELKAELRELELALLVLRLEELREELEE-LQEELKEAEEELEEL---TA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 445 KRAKAEDENETLRQQMIEVEISKQALQNELERLKE--SSLKRRstREMYKEKKTFNQQNggmerpgncRPATKTQRKLAP 522
Cdd:TIGR02168 261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANeiSRLEQQ--KQILRERLANLERQ---------LEELEAQLEELE 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 523 RRKD----DSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVdsplptgeaggppSTREAELKLRLK 598
Cdd:TIGR02168 330 SKLDelaeELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL-------------RSKVAQLELQIA 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 599 LVEEEANILGRKIVELEVENRGLKAEMEDMRGQQErEGPGRDHAPSIPTSPfgdslESSTELRRHLQFVEEEAELLRRSI 678
Cdd:TIGR02168 397 SLNNEIERLEARLERLEDRRERLQQEIEELLKKLE-EAELKELQAELEELE-----EELEELQEELERLEEALEELREEL 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 679 SEIEDHNRQLTHELSKFKFEpprepgwlGEGASPGAGGGAPLQEELKSARLQISELSGKVlklqhenhALLSNIQRCD-- 756
Cdd:TIGR02168 471 EEAEQALDAAERELAQLQAR--------LDSLERLQENLEGFSEGVKALLKNQSGLSGIL--------GVLSELISVDeg 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 757 ----LAAHLGLRAPSPRDSDAES-----DAGKKESDGEESRLPqPKREGPVGGESDSEEMFEKTSGF-GSGKPSEASEPC 826
Cdd:TIGR02168 535 yeaaIEAALGGRLQAVVVENLNAakkaiAFLKQNELGRVTFLP-LDSIKGTEIQGNDREILKNIEGFlGVAKDLVKFDPK 613
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 827 PTELLKAREDSEYLVTLKHEAQRL---ERTVERLITDTDSFLHDAGLRGGAPLPGPGLQGEEEQ------GEGDQQEPQL 897
Cdd:TIGR02168 614 LRKALSYLLGGVLVVDDLDNALELakkLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRReieeleEKIEELEEKI 693
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 898 LgTINAKMKAFKKELQAF---LEQVNRIGDGLSPLPHLTESSSFLSTVTSVSRDSPIGNLGKELGpDLQSRLKEQLEwQL 974
Cdd:TIGR02168 694 A-ELEKALAELRKELEELeeeLEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT-ELEAEIEELEE-RL 770
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 975 GPARG------DERESL----------------RLRAARELHRRADGDTGSHGLGGQtcfSLELRgppvLPEQSVSIEEL 1032
Cdd:TIGR02168 771 EEAEEelaeaeAEIEELeaqieqlkeelkalreALDELRAELTLLNEEAANLRERLE---SLERR----IAATERRLEDL 843
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217316411 1033 QGQL------VQAARLHQEETETFTNKIHKMEEEHLYALRWKELEMHSL--ALQNTLHE-RTWSDEKNLMQQELRSLKQ 1102
Cdd:TIGR02168 844 EEQIeelsedIESLAAEIEELEELIEELESELEALLNERASLEEALALLrsELEELSEElRELESKRSELRRELEELRE 922
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
443-795 |
1.53e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.00 E-value: 1.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 443 EEKRAKAEDENETLRQQMIEVEISKQALQNELERLKesslKRRSTREMYKEKKTFNQQNGGMERPGNCRPATKTQRKLAP 522
Cdd:TIGR02169 169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLR----REREKAERYQALLKEKREYEGYELLKEKEALERQKEAIER 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 523 RRkddsADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSlygdvDSPLPTGEAGGPPSTREAELKLRLKLVEE 602
Cdd:TIGR02169 245 QL----ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE-----EEQLRVKEKIGELEAEIASLERSIAEKER 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 603 EANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHApsipTSPFGDSLESSTELRRHLQFVEEEAELLRRSISEIE 682
Cdd:TIGR02169 316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKL----TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 683 DHNRQLTHELSKFKFEPPRepgwLGEGASPGAGGGAPLQEELKSARLQISELSGKVLKLQHENHALLSNIQRcdLAAHLG 762
Cdd:TIGR02169 392 EKLEKLKREINELKRELDR----LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ--LAADLS 465
|
330 340 350
....*....|....*....|....*....|...
gi 2217316411 763 lrapsprDSDAESDAGKKESDGEESRLPQPKRE 795
Cdd:TIGR02169 466 -------KYEQELYDLKEEYDRVEKELSKLQRE 491
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
133-383 |
1.70e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 56.53 E-value: 1.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 133 ARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGSR-APPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSSD 211
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAApAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 212 LSDCPSEPLSdeqrllPAASSDAESGTGSSDRePPRGAPTPSPAARGAPPGSPEPPallaaplaagacPGGRSIPSGVSG 291
Cdd:PRK07764 666 GDGWPAKAGG------AAPAAPPPAPAPAAPA-APAGAAPAQPAPAPAATPPAGQA------------DDPAAQPPQAAQ 726
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 292 GFAGPGVAEDVRGRSPPERPVPGTPKEPSLGEQSRLVPAAEEEELLREMEELRSEndylkdELDELRAEMEEMRDSYLEE 371
Cdd:PRK07764 727 GASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE------EEEMAEDDAPSMDDEDRRD 800
|
250
....*....|...
gi 2217316411 372 -DVYQLQELRREL 383
Cdd:PRK07764 801 aEEVAMELLEEEL 813
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
81-331 |
1.83e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 56.40 E-value: 1.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 81 AGKAPPS-PGSLAAPGrlsRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKG 159
Cdd:PRK07003 369 GGGVPARvAGAVPAPG---ARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADG 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 160 RKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARcsrishtdsssdlSDCPSEPLSdeqrllPAASSDAESGTG 239
Cdd:PRK07003 446 DAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAP-------------PDAAFEPAP------RAAAPSAATPAA 506
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 240 SSDREPPRGAPTPSPAARGAPPgSPEPPALLAAPLAAGACPGGRSIP---------------SGVSGGFAGPGVAEDVRG 304
Cdd:PRK07003 507 VPDARAPAAASREDAPAAAAPP-APEARPPTPAAAAPAARAGGAAAAldvlrnagmrvssdrGARAAAAAKPAAAPAAAP 585
|
250 260 270
....*....|....*....|....*....|
gi 2217316411 305 RSPPER---PVPgTPKEPSLGEQSRLVPAA 331
Cdd:PRK07003 586 KPAAPRvavQVP-TPRARAATGDAPPNGAA 614
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
350-568 |
2.04e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 56.27 E-value: 2.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRDsyleedvyqlqELRRELDRANKNCRILQYRLRKAEqKSLKVAETG------QVD--GELIRSL 421
Cdd:pfam05483 546 LRDELESVREEFIQKGD-----------EVKCKLDKSEENARSIEYEVLKKE-KQMKILENKcnnlkkQIEnkNKNIEEL 613
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 422 EQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQAlQNELERLKESSLkrrsTREMYKEKKTFNQqn 501
Cdd:pfam05483 614 HQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQK-EIEDKKISEEKL----LEEVEKAKAIADE-- 686
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217316411 502 ggmerpgncrpATKTQRKLaprrkddsaDLRCQLQFAkEEAFLMRKKMAKLGREKDELEQELQKYKS 568
Cdd:pfam05483 687 -----------AVKLQKEI---------DKRCQHKIA-EMVALMEKHKHQYDKIIEERDSELGLYKN 732
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
39-317 |
3.32e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 55.95 E-value: 3.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 39 HRAPSPARPFLKDLHARPAA--PGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAP---GRLSRRSGGVPGAKDKP-P 112
Cdd:PHA03307 118 PPTPPPASPPPSPAPDLSEMlrPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPlssPEETARAPSSPPAEPPPsT 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 113 PGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGSRA-----PPARTVGPPTPAARIPAVT 187
Cdd:PHA03307 198 PPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENecplpRPAPITLPTRIWEASGWNG 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 188 LAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARG--------- 258
Cdd:PHA03307 278 PSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSrspspsrpp 357
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316411 259 --APPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPK 317
Cdd:PHA03307 358 ppADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLD 418
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
350-696 |
4.29e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 55.46 E-value: 4.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEmrdsyLEEDVYQLQELRRELDRANKNCRILQYRLR---------KAEQKSL--KVAETGQVDG--- 415
Cdd:PRK03918 219 LREELEKLEKEVKE-----LEELKEEIEELEKELESLEGSKRKLEEKIReleerieelKKEIEELeeKVKELKELKEkae 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 416 ---ELIRSLEQDLKVAKDVSVRL---HHELKTVEEKRAKAEDENETLRqqmiEVEISKQALQNELERLKESSlkrrstrE 489
Cdd:PRK03918 294 eyiKLSEFYEEYLDELREIEKRLsrlEEEINGIEERIKELEEKEERLE----ELKKKLKELEKRLEELEERH-------E 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 490 MYKEKKTFNQQNGGMERPGNCRPATKTQRKLAPRRKddsadlrcqlqfAKEEaflMRKKMAKLGREKDELEQELQKYKSL 569
Cdd:PRK03918 363 LYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEK------------AKEE---IEEEISKITARIGELKKEIKELKKA 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 570 YGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANILGRKIvELEVENRGLKAEMEDMRGQQEREgpgRDHAPSIPTSP 649
Cdd:PRK03918 428 IEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELK-EIEEKERKLRKELRELEKVLKKE---SELIKLKELAE 503
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 2217316411 650 FGDSLESSTEL--RRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFK 696
Cdd:PRK03918 504 QLKELEEKLKKynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE 552
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
60-265 |
5.37e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 54.99 E-value: 5.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 60 GPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAE 139
Cdd:PRK07764 590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGW 669
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 140 PLSRAGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARipavtlAVTSVAGSPARCSRISHTDSSSDLSDCPSEP 219
Cdd:PRK07764 670 PAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAG------QADDPAAQPPQAAQGASAPSPAADDPVPLPP 743
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2217316411 220 LSDEQRLLPAASSDAESGTGSSDREPPrgAPTPSPAARGAPPGSPE 265
Cdd:PRK07764 744 EPDDPPDPAGAPAQPPPPPAPAPAAAP--AAAPPPSPPSEEEEMAE 787
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
346-921 |
9.11e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 54.28 E-value: 9.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 346 ENDYLKDE----LDELRAEMEEMRD-SYLEEDVYQLQELRRelDRANKNCRILQYRLRKAEQKSLKVAE---TGQVDgEL 417
Cdd:TIGR00606 502 EVKSLQNEkadlDRKLRKLDQEMEQlNHHTTTRTQMEMLTK--DKMDKDEQIRKIKSRHSDELTSLLGYfpnKKQLE-DW 578
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 418 IRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVE------ISKQALQNELERLKESSLKRRSTREMY 491
Cdd:TIGR00606 579 LHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEdklfdvCGSQDEESDLERLKEEIEKSSKQRAML 658
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 492 KEKKTFNQQ--NGGMERPGNCRPATKTQRKLAPRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSL 569
Cdd:TIGR00606 659 AGATAVYSQfiTQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSI 738
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 570 YGDVDSPLP-TGEAGGPPSTREAELKLRLklvEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTS 648
Cdd:TIGR00606 739 IDLKEKEIPeLRNKLQKVNRDIQRLKNDI---EEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKL 815
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 649 PFGDSLESSTELRrhlQFVEEEAELLRRSISEIE-------DHNRQLTHELSKFKfepprepgwlgegaspgagggaplq 721
Cdd:TIGR00606 816 QGSDLDRTVQQVN---QEKQEKQHELDTVVSKIElnrkliqDQQEQIQHLKSKTN------------------------- 867
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 722 eELKSARLQISELSGKVLKLQHENHALLSNIQRCDLAAHLGLRAPSPRDSDAESDAGKKE----SDGEESRLPQPKREgp 797
Cdd:TIGR00606 868 -ELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEelisSKETSNKKAQDKVN-- 944
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 798 vggesDSEEMFEKTSGFGSGKPSEASEPCPTELL-KAREDSEYLVTLKHEAQRLERTVERLITDTDSFlhdaglrggapl 876
Cdd:TIGR00606 945 -----DIKEKVKNIHGYMKDIENKIQDGKDDYLKqKETELNTVNAQLEECEKHQEKINEDMRLMRQDI------------ 1007
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 2217316411 877 pgpglqGEEEQGEGDQQEPQLLGTINAKMKAFKKELQAFLEQVNR 921
Cdd:TIGR00606 1008 ------DTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQ 1046
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
348-694 |
9.45e-07 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 53.37 E-value: 9.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 348 DYLKDELDELRAEMEEMRDsyleedvyQLQELRRELDRANKNCRILQYRLRKAEQKsLKVAETGQvdgeliRSLEQDLKV 427
Cdd:COG4372 41 DKLQEELEQLREELEQARE--------ELEQLEEELEQARSELEQLEEELEELNEQ-LQAAQAEL------AQAQEELES 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 428 AKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKEsslkrrstremykEKKTFNQQNGGMERP 507
Cdd:COG4372 106 LQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEE-------------QLESLQEELAALEQE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 508 GNCRPATKTQRKLAPRRKddsaDLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPS 587
Cdd:COG4372 173 LQALSEAEAEQALDELLK----EANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDK 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 588 T---REAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLESSTELRRHL 664
Cdd:COG4372 249 EellEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKL 328
|
330 340 350
....*....|....*....|....*....|
gi 2217316411 665 QFVEEEAELLRRSISEIEDHNRQLTHELSK 694
Cdd:COG4372 329 ELALAILLAELADLLQLLLVGLLDNDVLEL 358
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
350-635 |
1.28e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.79 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRDsyleedvyQLQELRRELDRANKNCRILQYRLRKAEQKslkvaetgqvdgelIRSLEQDLKVAK 429
Cdd:COG1196 258 LEAELAELEAELEELRL--------ELEELELELEEAQAEEYELLAELARLEQD--------------IARLEERRRELE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 430 DVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKtfnqqnggmerpgn 509
Cdd:COG1196 316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL-------------- 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 510 crpATKTQRKLAPRRkdDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVdsplptgeaggppSTR 589
Cdd:COG1196 382 ---EELAEELLEALR--AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE-------------EEA 443
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 2217316411 590 EAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERE 635
Cdd:COG1196 444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
350-751 |
1.30e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 53.49 E-value: 1.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRD------SYLEEDVYQLQELRRELDRANKNCRILQYRLR--KAEQKSLKvaetGQVDGELIRSL 421
Cdd:TIGR04523 237 KQQEINEKTTEISNTQTqlnqlkDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNqlKSEISDLN----NQKEQDWNKEL 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 422 EQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERlKESSLKRrstreMYKEKKTFNQQN 501
Cdd:TIGR04523 313 KSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEE-KQNEIEK-----LKKENQSYKQEI 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 502 ggmerpgncrpatktqRKLaprrKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGE 581
Cdd:TIGR04523 387 ----------------KNL----ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLT 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 582 aggppsTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMrgQQEREGPGRDHapSIPTSPFGDSLESSTELR 661
Cdd:TIGR04523 447 ------NQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQK--QKELKSKEKEL--KKLNEEKKELEEKVKDLT 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 662 RHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFepprepgwlgegaspgagggaplqeELKSARL--QISELSGKVL 739
Cdd:TIGR04523 517 KKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF-------------------------ELKKENLekEIDEKNKEIE 571
|
410
....*....|..
gi 2217316411 740 KLQHENHALLSN 751
Cdd:TIGR04523 572 ELKQTQKSLKKK 583
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
6-264 |
1.32e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 53.73 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 6 GPAGGGAPDAklqppgqhhrHHHLHPVAERRRLHRAPSPARPflkdlharPAAPGPAVPSSGRAPAPAAPRSPNLAGKAP 85
Cdd:PRK12323 366 GQSGGGAGPA----------TAAAAPVAQPAPAAAAPAAAAP--------APAAPPAAPAAAPAAAAAARAVAAAPARRS 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 86 PSPGSLAAP-GRLSRRSGGVPGAKDKPPPGAgaraaggakaalgsrrAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKR 164
Cdd:PRK12323 428 PAPEALAAArQASARGPGGAPAPAPAPAAAP----------------AAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP 491
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 165 GSRAPPARTVGPPTPAARIPAvtlavtsvagsparcsrishtDSSSDLSDCPSEPLSDEqrllpaaSSDAESGTGSSDRE 244
Cdd:PRK12323 492 ADDDPPPWEELPPEFASPAPA---------------------QPDAAPAGWVAESIPDP-------ATADPDDAFETLAP 543
|
250 260
....*....|....*....|
gi 2217316411 245 PPRGAPTPSPAARGAPPGSP 264
Cdd:PRK12323 544 APAAAPAPRAAAATEPVVAP 563
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
350-615 |
1.52e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.40 E-value: 1.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRDSY---------LEEDVY----QLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGE 416
Cdd:COG1196 272 LRLELEELELELEEAQAEEyellaelarLEQDIArleeRRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 417 LIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKT 496
Cdd:COG1196 352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 497 FNQQNGGMERpgncRPATKTQRKLApRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDvdsp 576
Cdd:COG1196 432 ELEEEEEEEE----EALEEAAEEEA-ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD---- 502
|
250 260 270
....*....|....*....|....*....|....*....
gi 2217316411 577 lptgEAGGPPSTREAELKLRLKLVEEEANILGRKIVELE 615
Cdd:COG1196 503 ----YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
346-484 |
1.63e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 1.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 346 ENDYLKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDL 425
Cdd:TIGR02169 351 RRDKLTEEYAELKEELEDLRAELEEVDK-EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI 429
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316411 426 KVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKE--SSLKR 484
Cdd:TIGR02169 430 AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKelSKLQR 490
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
54-313 |
2.71e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 52.54 E-value: 2.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 54 ARPAAPGPAVPSS-----GRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRSGGVPGAKD-------KPPPGAGARAAG 121
Cdd:PRK07003 361 AVTGGGAPGGGVParvagAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATraeappaAPAPPATADRGD 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 122 GAKAALGSRRAARVAPAEPLSRAGkPPGAEPPSAAAKgrKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCS 201
Cdd:PRK07003 441 DAADGDAPVPAKANARASADSRCD-ERDAQPPADSGS--ASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAS 517
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 202 RishtdssSDLSDCPSEPLSDEQRLLPAASSDAESGTG---------------SSDREPPRGAPTPSPAARGAPPGSPEP 266
Cdd:PRK07003 518 R-------EDAPAAAAPPAPEARPPTPAAAAPAARAGGaaaaldvlrnagmrvSSDRGARAAAAAKPAAAPAAAPKPAAP 590
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2217316411 267 PALLAAPLaagacPGGRSIPSGVSGGFAGPGV-AEDVRGRSPPERPVP 313
Cdd:PRK07003 591 RVAVQVPT-----PRARAATGDAPPNGAARAEqAAESRGAPPPWEDIP 633
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
345-687 |
3.92e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 3.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 345 SENDYLKDELDELRAEMEEMRDsyleedvyQLQELRRELDRANKNCRILQYRLRKAEQKslkvaetgqvdgelIRSLEQD 424
Cdd:TIGR02169 695 SELRRIENRLDELSQELSDASR--------KIGEIEKEIEQLEQEEEKLKERLEELEED--------------LSSLEQE 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 425 LKVAKDVSVRLHHELKTVEEKRAKAEDENETL-----RQQMIEVEISKQALQNELERLK------ESSLKRRSTREMYKE 493
Cdd:TIGR02169 753 IENVKSELKELEARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSRIEarlreiEQKLNRLTLEKEYLE 832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 494 KKTFNQQNGgmerpgncRPATKTQRKLAPRRKDDS-ADLRCQLQFAKE-EAFL--MRKKMAKLGREKDELEQELQKYKSL 569
Cdd:TIGR02169 833 KEIQELQEQ--------RIDLKEQIKSIEKEIENLnGKKEELEEELEElEAALrdLESRLGDLKKERDELEAQLRELERK 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 570 YGDVDSPLPTGEaggppsTREAELKLRLKLVEEEANILGRKIVELEVEN------RGLKAEMEDMRGQQEREGPGRDHAP 643
Cdd:TIGR02169 905 IEELEAQIEKKR------KRLSELKAKLEALEEELSEIEDPKGEDEEIPeeelslEDVQAELQRVEEEIRALEPVNMLAI 978
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 2217316411 644 siptSPFGDSLESSTELRRHLQFVEEEAELLRRSISEIEDHNRQ 687
Cdd:TIGR02169 979 ----QEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
350-485 |
4.51e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.22 E-value: 4.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRANKncrilqyRLRKAEQKSLKVAetgqvdgELIRSLEQDLKVAK 429
Cdd:COG4913 314 LEARLDALREELDELEAQIRGNGGDRLEQLEREIERLER-------ELEERERRRARLE-------ALLAALGLPLPASA 379
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2217316411 430 DVSVRLHHELKtveEKRAKAEDENETLRQQMIEVEISKQALQNELERLKE--SSLKRR 485
Cdd:COG4913 380 EEFAALRAEAA---ALLEALEEELEALEEALAEAEAALRDLRRELRELEAeiASLERR 434
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
350-696 |
5.44e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 51.60 E-value: 5.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEmrdsyLEEDVYQLQELRRELDRANK--------NCRILQYRLRKAEQKSLKVAETGQVDGELIRSL 421
Cdd:PRK03918 343 LKKKLKELEKRLEE-----LEERHELYEEAKAKKEELERlkkrltglTPEKLEKELEELEKAKEEIEEEISKITARIGEL 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 422 EQ----------DLKVAK----------------DVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVE--ISKQ----A 469
Cdd:PRK03918 418 KKeikelkkaieELKKAKgkcpvcgrelteehrkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEkvLKKEseliK 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 470 LQNELERLK--ESSLKRRSTREMYKEKKTF---NQQNGGMErpGNCRPATKTQRKLAPRRKdDSADLRCQLQFAKEEAFL 544
Cdd:PRK03918 498 LKELAEQLKelEEKLKKYNLEELEKKAEEYeklKEKLIKLK--GEIKSLKKELEKLEELKK-KLAELEKKLDELEEELAE 574
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 545 MRKKMAKLGREK-DELEQELQKYKSLYGDVDsplptgEAGGPPSTREAELKlRLKLVEEEANILGRKIVELEVENRGLKA 623
Cdd:PRK03918 575 LLKELEELGFESvEELEERLKELEPFYNEYL------ELKDAEKELEREEK-ELKKLEEELDKAFEELAETEKRLEELRK 647
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217316411 624 EMEDMR---GQQEREGPGRDHapsiptspfgdslessTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFK 696
Cdd:PRK03918 648 ELEELEkkySEEEYEELREEY----------------LELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
351-635 |
6.73e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.68 E-value: 6.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 351 KDELDELRAEMEEMRDSylEEDVYQLQELRRELDRANKNCRILQY--RLRKAEQK----SLKVAETGQVDGELIRSLE-- 422
Cdd:PTZ00121 1469 AKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADEAKKAAEAKKKadEAKKAEEAkkadEAKKAEEAKKADEAKKAEEkk 1546
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 423 --QDLKVAKDVsvRLHHELKTVEEKRAKAEDENETLRQqmieVEISKQAlqnELERLKESSLKRRSTREMYKEKktFNQQ 500
Cdd:PTZ00121 1547 kaDELKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRK----AEEAKKA---EEARIEEVMKLYEEEKKMKAEE--AKKA 1615
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 501 NGGMERPGNCRPATKTQRKLAPRRKDDSADLRCQLQFAKEEaflmRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTG 580
Cdd:PTZ00121 1616 EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE----EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA 1691
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2217316411 581 EAggppSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERE 635
Cdd:PTZ00121 1692 EA----LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED 1742
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
350-696 |
7.03e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 51.28 E-value: 7.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEmRDSYLEEDVYQLQELRRELDRANKNCR---ILQYRLRKAeQKSLKVAEtgQVDGELIRSL---EQ 423
Cdd:pfam05557 109 LKNELSELRRQIQR-AELELQSTNSELEELQERLDLLKAKASeaeQLRQNLEKQ-QSSLAEAE--QRIKELEFEIqsqEQ 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 424 DLKVAKDVSV-------------RLHHELK--------------TVEEKRAKAEDEnETLRQQMIEVEISKQALQNEL-- 474
Cdd:pfam05557 185 DSEIVKNSKSelaripelekeleRLREHNKhlnenienklllkeEVEDLKRKLERE-EKYREEAATLELEKEKLEQELqs 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 475 -ERLKESS--------LKRRSTREMYKEKKTFNQQNGGMERpgNCRPATKTQRKLAPRRKDDSA---DLRCQLQFAKEEA 542
Cdd:pfam05557 264 wVKLAQDTglnlrspeDLSRRIEQLQQREIVLKEENSSLTS--SARQLEKARRELEQELAQYLKkieDLNKKLKRHKALV 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 543 FLMRKKMAKLGREKDELEQELQKYkslygdvDSPLPTGEAGGPPSTREAEL-----KLRLKLVEEEANI--LGRKIVELE 615
Cdd:pfam05557 342 RRLQRRVLLLTKERDGYRAILESY-------DKELTMSNYSPQLLERIEEAedmtqKMQAHNEEMEAQLsvAEEELGGYK 414
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 616 VENRGLKAEMEDMRGQQEREGPGRdhapsiptspfgdSLESSTELRRHLQFVEEEAELLRRSI----SEIEDHNRQLTHE 691
Cdd:pfam05557 415 QQAQTLERELQALRQQESLADPSY-------------SKEEVDSLRRKLETLELERQRLREQKneleMELERRCLQGDYD 481
|
....*
gi 2217316411 692 LSKFK 696
Cdd:pfam05557 482 PKKTK 486
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
358-567 |
7.96e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.30 E-value: 7.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 358 RAEMEEMRDSYLEEDVYQLQELRREldranKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHH 437
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKA-----EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE 1665
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 438 ELKTVEEKRAKAEdenETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKE---KKTFNQQNGGMERPGncRPAT 514
Cdd:PTZ00121 1666 EAKKAEEDKKKAE---EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAeelKKAEEENKIKAEEAK--KEAE 1740
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2217316411 515 KTQRKLAPRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYK 567
Cdd:PTZ00121 1741 EDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRR 1793
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
351-645 |
2.26e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 49.66 E-value: 2.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 351 KDELDELR---AEMEEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLkv 427
Cdd:TIGR00606 244 ENELDPLKnrlKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKEREL-- 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 428 akdvsVRLHHELKtveekraKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNqqngGMERP 507
Cdd:TIGR00606 322 -----VDCQRELE-------KLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELD----GFERG 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 508 GNCRPATKTQRKLAPRRKDDSA--------DLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPT 579
Cdd:TIGR00606 386 PFSERQIKNFHTLVIERQEDEAktaaqlcaDLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQ 465
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217316411 580 GEaGGPPSTREAELKLR-----LKLVEEEANILGRKIVELEVEN------RGLKAEMEDMRgQQEREGPGRDHAPSI 645
Cdd:TIGR00606 466 LE-GSSDRILELDQELRkaereLSKAEKNSLTETLKKEVKSLQNekadldRKLRKLDQEME-QLNHHTTTRTQMEML 540
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
352-692 |
2.85e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.55 E-value: 2.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 352 DELDELRAEMEEmrdsyleedvyQLQELRRELDRANKNcRILQYRLRKAEQKSLKVAetgqvdgelIRSLEQDLKVAKDV 431
Cdd:COG1196 189 ERLEDILGELER-----------QLEPLERQAEKAERY-RELKEELKELEAELLLLK---------LRELEAELEELEAE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 432 SVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQQNggMERpgncr 511
Cdd:COG1196 248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER--LEE----- 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 512 pATKTQRKLAPRRKDDSAdlrcQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKslygdvdsplptgeaggppSTREA 591
Cdd:COG1196 321 -LEEELAELEEELEELEE----ELEELEEELEEAEEELEEAEAELAEAEEALLEAE-------------------AELAE 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 592 ELKLRLKLVEEEANILgRKIVELEVENRGLKAEMEDMRGQQEREgpgrdhapsiptspfgdsLESSTELRRHLQFVEEEA 671
Cdd:COG1196 377 AEEELEELAEELLEAL-RAAAELAAQLEELEEAEEALLERLERL------------------EEELEELEEALAELEEEE 437
|
330 340
....*....|....*....|.
gi 2217316411 672 ELLRRSISEIEDHNRQLTHEL 692
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEE 458
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
41-297 |
3.28e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 49.40 E-value: 3.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 41 APSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPgsLAAPGRLSRRSGGVPGAKDKPPPGAGARAA 120
Cdd:PHA03307 48 AELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTL--APASPAREGSPTPPGPSSPDPPPPTPPPAS 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 121 GGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTLAV-TSVAGSPAR 199
Cdd:PHA03307 126 PPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPsTPPAAASPR 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 200 CSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPA--------ARGAPPGSPEPPALLA 271
Cdd:PHA03307 206 PPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPApitlptriWEASGWNGPSSRPGPA 285
|
250 260
....*....|....*....|....*.
gi 2217316411 272 APLAAGACPGGRSIPSGVSGGFAGPG 297
Cdd:PHA03307 286 SSSSSPRERSPSPSPSSPGSGPAPSS 311
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
351-629 |
3.87e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.98 E-value: 3.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 351 KDELDELRaEMEEMRDSyleEDVYQLQELRRELDRANKNCRILQyRLRKAEQKslKVAETGQVDGELIRSLEQDLKVAKD 430
Cdd:PTZ00121 1545 KKKADELK-KAEELKKA---EEKKKAEEAKKAEEDKNMALRKAE-EAKKAEEA--RIEEVMKLYEEEKKMKAEEAKKAEE 1617
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 431 VSVRLhHELKTVEEKRAKAEDENETLRQQMIEVEISKQAlqNELERLKESSLKRRSTREMYKEKKTFNQQNGGMERPGNC 510
Cdd:PTZ00121 1618 AKIKA-EELKKAEEEKKKVEQLKKKEAEEKKKAEELKKA--EEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEAL 1694
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 511 RPATKTQRKLAPRRKDDSADLRCQLQFAKEEaflmRKKMAKLGREKDELEQELQKYKSLYGDvdsplpTGEaggppSTRE 590
Cdd:PTZ00121 1695 KKEAEEAKKAEELKKKEAEEKKKAEELKKAE----EENKIKAEEAKKEAEEDKKKAEEAKKD------EEE-----KKKI 1759
|
250 260 270
....*....|....*....|....*....|....*....
gi 2217316411 591 AELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMR 629
Cdd:PTZ00121 1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
6-264 |
4.49e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.78 E-value: 4.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 6 GPAGGGAPDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGP----AVPSSGRAPAPAAPRSPNLA 81
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPpptsAQPTAPPPPPGPPPPSLPLG 2853
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 82 GKAPP------------SPGSLAAPGR----------LSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAE 139
Cdd:PHA03247 2854 GSVAPggdvrrrppsrsPAAKPAAPARppvrrlarpaVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 140 PLSRAGKPPGAEPPSAAAKGRKAKR-----------GSRAPPARTVGPPTPAARIPAVTlaVTSVAGSPArcSRISHTDS 208
Cdd:PHA03247 2934 PPPPRPQPPLAPTTDPAGAGEPSGAvpqpwlgalvpGRVAVPRFRVPQPAPSREAPASS--TPPLTGHSL--SRVSSWAS 3009
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 209 SSDLS-DCPSEPLSDEQRLLPAASSDAESGTGSSDREPPR---GAPTPSPAARGAPPGSP 264
Cdd:PHA03247 3010 SLALHeETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERsdlEALDPLPPEPHDPFAHE 3069
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
358-645 |
5.28e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 48.58 E-value: 5.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 358 RAEME-EMRDSYLEedvyqLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQvdgELIRSLeQDLKVAKDvsvRLH 436
Cdd:pfam15921 592 KAQLEkEINDRRLE-----LQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGS---ERLRAV-KDIKQERD---QLL 659
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 437 HELKTVEEKRAKAEDENETL----RQQMIEVEISKQALQNELerlkesslkRRSTREMYKEKKTFNQQNGGmerPGNC-R 511
Cdd:pfam15921 660 NEVKTSRNELNSLSEDYEVLkrnfRNKSEEMETTTNKLKMQL---------KSAQSELEQTRNTLKSMEGS---DGHAmK 727
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 512 PATKTQRKLAPRRKDDSAdLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVdsplptgeAGGPPSTREA 591
Cdd:pfam15921 728 VAMGMQKQITAKRGQIDA-LQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM--------AGELEVLRSQ 798
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316411 592 ELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQ-------QEREGPGRDHAPSI 645
Cdd:pfam15921 799 ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKlqhtldvKELQGPGYTSNSSM 859
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
354-585 |
5.73e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.37 E-value: 5.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 354 LDELRAEMEEmrdsyLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGElIRSLEQDLKVAKDVSV 433
Cdd:COG4913 612 LAALEAELAE-----LEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAERE-IAELEAELERLDASSD 685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 434 rlhhELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKEsslkrrstremykEKKTFNQQNGGMERPGNCRPA 513
Cdd:COG4913 686 ----DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEE-------------ELDELQDRLEAAEDLARLELR 748
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217316411 514 TKTQRKLA-----PRRKDDSADLRCQLQFAKeeaflmrkkmAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGP 585
Cdd:COG4913 749 ALLEERFAaalgdAVERELRENLEERIDALR----------ARLNRAEEELERAMRAFNREWPAETADLDADLESLP 815
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
375-565 |
5.95e-05 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 48.21 E-value: 5.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 375 QLQELRRELDRANKNcriLQYRLRKAEQKSLKVAETGQVD----GELIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAE 450
Cdd:pfam07111 482 ELEQLREERNRLDAE---LQLSAHLIQQEVGRAREQGEAErqqlSEVAQQLEQELQRAQESLASVGQQLEVARQGQQEST 558
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 451 DENETLRQQMI-EVEISKQALQN---ELE-RLKE--SSLKRR---STREMYKEKKTFNQqnggmerpgncrpatkTQRKl 520
Cdd:pfam07111 559 EEAASLRQELTqQQEIYGQALQEkvaEVEtRLREqlSDTKRRlneARREQAKAVVSLRQ----------------IQHR- 621
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2217316411 521 APRRKDDSADL-RCQLQFAKEEAFLMRKKMAKLGREKDELEQELQK 565
Cdd:pfam07111 622 ATQEKERNQELrRLQDEARKEEGQRLARRVQELERDKNLMLATLQQ 667
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
86-218 |
6.97e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 47.75 E-value: 6.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 86 PSPGSLAAPGRLSRRSGGVPGAKDKPPPGagaraaggakaalgSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRG 165
Cdd:PRK14959 373 PSGGGASAPSGSAAEGPASGGAATIPTPG--------------TQGPQGTAPAAGMTPSSAAPATPAPSAAPSPRVPWDD 438
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2217316411 166 SRAPPARTVGPPTPAARIPavtlAVTSVAGSPARCSRISHTDSSSDLSDCPSE 218
Cdd:PRK14959 439 APPAPPRSGIPPRPAPRMP----EASPVPGAPDSVASASDAPPTLGDPSDTAE 487
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
55-261 |
7.64e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 47.95 E-value: 7.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 55 RPAAPGPAVPSSGRAPAPAAprspnlAGKAPPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAAR 134
Cdd:PRK12323 359 RMLAFRPGQSGGGAGPATAA------AAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEA 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 135 VAPAEPLSRAGKPPGAEPPSAAAkgrkakrgsrAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSS--SDL 212
Cdd:PRK12323 433 LAAARQASARGPGGAPAPAPAPA----------AAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPpwEEL 502
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2217316411 213 SDCPSEPLSDEQRLLPA-ASSDAESGTGSSDREPPRGAPTPSPAARGAPP 261
Cdd:PRK12323 503 PPEFASPAPAQPDAAPAgWVAESIPDPATADPDDAFETLAPAPAAAPAPR 552
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
350-494 |
1.35e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.69 E-value: 1.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDG---ElIRSLEQDLK 426
Cdd:COG1579 29 LPAELAELEDELAALEARLEAAKT-ELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEAlqkE-IESLKRRIS 106
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217316411 427 VAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVeisKQALQNELERLKESSLKRRSTREMYKEK 494
Cdd:COG1579 107 DLEDEILELMERIEELEEELAELEAELAELEAELEEK---KAELDEELAELEAELEELEAEREELAAK 171
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
352-617 |
1.41e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 1.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 352 DELDELRAEMEEMRDsyleedvyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETgqvdgelIRSLEQDLKVAKDv 431
Cdd:COG4942 20 DAAAEAEAELEQLQQ--------EIAELEKELAALKKEEKALLKQLAALERRIAALARR-------IRALEQELAALEA- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 432 svrlhhELKTVEEKRAKAEDENETLRQQMIEV--EISKQALQNELERLkessLKRRSTREMYKEKKTFNQQNggmerpgn 509
Cdd:COG4942 84 ------ELAELEKEIAELRAELEAQKEELAELlrALYRLGRQPPLALL----LSPEDFLDAVRRLQYLKYLA-------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 510 crPATKTQRKLAPRRKDDSADLRCQLQFAKEEaflMRKKMAKLGREKDELEQELQKYKSLYGDVdsplptgeaggppSTR 589
Cdd:COG4942 146 --PARREQAEELRADLAELAALRAELEAERAE---LEALLAELEEERAALEALKAERQKLLARL-------------EKE 207
|
250 260
....*....|....*....|....*...
gi 2217316411 590 EAELKLRLKLVEEEANILGRKIVELEVE 617
Cdd:COG4942 208 LAELAAELAELQQEAEELEALIARLEAE 235
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
350-635 |
1.80e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.68 E-value: 1.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQK------SLKVAETGQVDGELIRSLEQ 423
Cdd:COG4717 168 LEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEleeleeELEQLENELEAAALEERLKE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 424 DLKVAKDVSVRLHHE----------------------------LKTVEEKRAKAEDENETLRQQMIEvEISKQALQNELE 475
Cdd:COG4717 248 ARLLLLIAAALLALLglggsllsliltiagvlflvlgllallfLLLAREKASLGKEAEELQALPALE-ELEEEELEELLA 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 476 RLK-ESSLKRRSTREMYKEKKTFNQQNGGMERpgncrpaTKTQRKLAPRRKDDSADLRcQLQFAKEEAFLMRkkmAKLGR 554
Cdd:COG4717 327 ALGlPPDLSPEELLELLDRIEELQELLREAEE-------LEEELQLEELEQEIAALLA-EAGVEDEEELRAA---LEQAE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 555 EKDELEQELQKYKSLYGDVDSPLPTGEAGGPPST---REAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQ 631
Cdd:COG4717 396 EYQELKEELEELEEQLEELLGELEELLEALDEEEleeELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELL 475
|
....
gi 2217316411 632 QERE 635
Cdd:COG4717 476 QELE 479
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
82-326 |
1.86e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 46.70 E-value: 1.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 82 GKAPPSPGSLAAPGRLSRRSGGvPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAG-------KPPGAEPPS 154
Cdd:PHA03307 69 TGPPPGPGTEAPANESRSTPTW-SLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPApdlsemlRPVGSPGPP 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 155 AAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAG----SPARCSRISHTDSSSDLSDcPSEPLSDEQRLLPAA 230
Cdd:PHA03307 148 PAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSppaePPPSTPPAAASPRPPRRSS-PISASASSPAPAPGR 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 231 SSDAESGTGSSDREPPRGAPTPSpAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPgvaedvRGRSPPer 310
Cdd:PHA03307 227 SAADDAGASSSDSSSSESSGCGW-GPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSP------RERSPS-- 297
|
250
....*....|....*.
gi 2217316411 311 PVPGTPKEPSLGEQSR 326
Cdd:PHA03307 298 PSPSSPGSGPAPSSPR 313
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
350-479 |
2.24e-04 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 46.00 E-value: 2.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRDSYL--EEDVYQLQELRRELDRANKNCRILQYRLRKAEQ-------------KSLKVAETGQVD 414
Cdd:pfam06160 303 AEEQNKELKEELERVQQSYTlnENELERVRGLEKQLEELEKRYDEIVERLEEKEVayselqeeleeilEQLEEIEEEQEE 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 415 G-ELIRSLEQDLKVAKDVSVRLHHELKTVE---EKR-------------AKAEDENETLRQQMIEV-----EISKQAL-- 470
Cdd:pfam06160 383 FkESLQSLRKDELEAREKLDEFKLELREIKrlvEKSnlpglpesyldyfFDVSDEIEDLADELNEVplnmdEVNRLLDea 462
|
....*....
gi 2217316411 471 QNELERLKE 479
Cdd:pfam06160 463 QDDVDTLYE 471
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
12-265 |
2.65e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.13 E-value: 2.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 12 APDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPflkdlhARPAAPGPAVPSSGRapapaAPRSPNLAGKAPPSPGSL 91
Cdd:PRK07764 589 GPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAP------AAPAPAGAAAAPAEA-----SAAPAPGVAAPEHHPKHV 657
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 92 AAPGRLSRRSGGVPGAKDKPPPgagaraaggakaalgsrrAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGSRAPPA 171
Cdd:PRK07764 658 AVPDASDGGDGWPAKAGGAAPA------------------APPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAA 719
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 172 RTVGPPTPAARIPAVTLAVTSVAGSParcsrishtdsssDLSDCPSEPLSDEQrllPAASSDAESGTGSSDREPPRGAPT 251
Cdd:PRK07764 720 QPPQAAQGASAPSPAADDPVPLPPEP-------------DDPPDPAGAPAQPP---PPPAPAPAAAPAAAPPPSPPSEEE 783
|
250
....*....|....
gi 2217316411 252 PSPAARGAPPGSPE 265
Cdd:PRK07764 784 EMAEDDAPSMDDED 797
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
144-264 |
2.70e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 45.86 E-value: 2.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 144 AGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTL-AVTSVAGSPArcSRISHTDSSSDLSDCPSEPLSD 222
Cdd:PRK14951 363 AFKPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPaAAASAPAAPP--AAAPPAPVAAPAAAAPAAAPAA 440
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2217316411 223 EQRLLPAASSDAESGTGSSDREPPRGAPTPSPA-ARGAPPGSP 264
Cdd:PRK14951 441 APAAVALAPAPPAQAAPETVAIPVRVAPEPAVAsAAPAPAAAP 483
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
131-264 |
2.83e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.13 E-value: 2.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 131 RAARVAPAEPLSRAGKPPGAEPPSAAAkgrkAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSS 210
Cdd:PRK07764 377 RLERLERRLGVAGGAGAPAAAAPSAAA----AAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGG 452
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2217316411 211 DLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSP 264
Cdd:PRK07764 453 APSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGA 506
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
350-499 |
3.05e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.20 E-value: 3.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVA- 428
Cdd:TIGR02168 356 LEAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAe 434
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217316411 429 -KDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQ 499
Cdd:TIGR02168 435 lKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSE 506
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
338-694 |
4.50e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.35 E-value: 4.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 338 REMEELRSENDYLKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRankncRILQYRLRKAEQKSLKvaetgqVDGEL 417
Cdd:pfam02463 177 KLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE-----YLLYLDYLKLNEERID------LLQEL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 418 IRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDEnetlrQQMIEVEISKQALQNELERLKESSLKRRSTREmyKEKKTF 497
Cdd:pfam02463 246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKE-----KKLQEEELKLLAKEEEELKSELLKLERRKVDD--EEKLKE 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 498 NQQNggmerpgncrpATKTQRKLAPRRKDdsadlrcQLQFAKEEAFLMRKKmAKLGREKDELEQELQKYKSLYGDVDSPL 577
Cdd:pfam02463 319 SEKE-----------KKKAEKELKKEKEE-------IEELEKELKELEIKR-EAEEEEEEELEKLQEKLEQLEEELLAKK 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 578 PTGEAGGPPSTREAELKLRLKLVEEeaNILGRKIVELEVENRGLKAEMEDMRGQQEREGpgrdhapsiptsPFGDSLESS 657
Cdd:pfam02463 380 KLESERLSSAAKLKEEELELKSEEE--KEAQLLLELARQLEDLLKEEKKEELEILEEEE------------ESIELKQGK 445
|
330 340 350
....*....|....*....|....*....|....*..
gi 2217316411 658 TELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSK 694
Cdd:pfam02463 446 LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKL 482
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
102-323 |
4.55e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 4.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 102 GGVPGAKDKPPPGAGARAAGGAKAalgSRRAARVAPAEPlSRAGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAA 181
Cdd:PRK07764 589 GPAPGAAGGEGPPAPASSGPPEEA---ARPAAPAAPAAP-AAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 182 RIPAVTLAVTSVAGSParcsrishtdsssdlsdcPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPP 261
Cdd:PRK07764 665 GGDGWPAKAGGAAPAA------------------PPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQ 726
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217316411 262 GSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSLGE 323
Cdd:PRK07764 727 GASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAED 788
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
13-319 |
4.88e-04 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 45.05 E-value: 4.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 13 PDAKLQPPGQHHRHHHLHPVAERrrLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLA 92
Cdd:COG5180 158 SDPILAKDPDGDSASTLPPPAEK--LDKVLTEPRDALKDSPEKLDRPKVEVKDEAQEEPPDLTGGADHPRPEAASSPKVD 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 93 APGRLSRRSGgvPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAA-AKGRKAKRGSRAPPA 171
Cdd:COG5180 236 PPSTSEARSR--PATVDAQPEMRPPADAKERRRAAIGDTPAAEPPGLPVLEAGSEPQSDAPEAEtARPIDVKGVASAPPA 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 172 RTVGPPTPAAR---IPAVTLAVTSVAGSPARCSRISHTDSSSDlsdcPSEPLSDEQRLLPAASSDAESGTGSSDREPPRG 248
Cdd:COG5180 314 TRPVRPPGGARdpgTPRPGQPTERPAGVPEAASDAGQPPSAYP----PAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNG 389
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316411 249 APTPSPaARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAedvrgRSPPERPVPGTPKEP 319
Cdd:COG5180 390 APQPGL-GRRGAPGPPMGAGDLVQAALDGGGRETASLGGAAGGAGQGPKAD-----FVPGDAESVSGPAGL 454
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
352-496 |
5.06e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.52 E-value: 5.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 352 DELDELRAEMEEMRDsylEEDVYQLQELRRELDRANKNCRILQyrlRKAEQKSlKVAETGQVDGELIRSLEQDLKVAKDV 431
Cdd:PTZ00121 1656 EEENKIKAAEEAKKA---EEDKKKAEEAKKAEEDEKKAAEALK---KEAEEAK-KAEELKKKEAEEKKKAEELKKAEEEN 1728
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217316411 432 SVRLHHELKTVEEKRAKAE----DENETLRQQMIEVEISKQALQNELER---LKESSLKRRSTREMYKEKKT 496
Cdd:PTZ00121 1729 KIKAEEAKKEAEEDKKKAEeakkDEEEKKKIAHLKKEEEKKAEEIRKEKeavIEEELDEEDEKRRMEVDKKI 1800
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
346-500 |
5.20e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.11 E-value: 5.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 346 ENDYLKDELDELRAE--MEEMRDSYLEEDVYQLQELRRELDRANKN--CRILQYRLRKAEQKSLKVAETgQVDGELIRSL 421
Cdd:pfam17380 390 KNERVRQELEAARKVkiLEEERQRKIQQQKVEMEQIRAEQEEARQRevRRLEEERAREMERVRLEEQER-QQQVERLRQQ 468
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 422 EQDLKVAKDVSVRLHHELKTVEEKRAKA-EDENETLRQQMIEVEISKQALQNELE----------RLKESSLKRRSTREM 490
Cdd:pfam17380 469 EEERKRKKLELEKEKRDRKRAEEQRRKIlEKELEERKQAMIEEERKRKLLEKEMEerqkaiyeeeRRREAEEERRKQQEM 548
|
170
....*....|
gi 2217316411 491 yKEKKTFNQQ 500
Cdd:pfam17380 549 -EERRRIQEQ 557
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
345-569 |
5.41e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 44.13 E-value: 5.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 345 SENDYLKDELDELRAEMEEMRDSYLE---------EDVYQLQELRRELDRANKNCRILQYRLRKAEQKSlkvaETGQVDG 415
Cdd:COG1340 57 EEAQELREKRDELNEKVKELKEERDElneklnelrEELDELRKELAELNKAGGSIDKLRKEIERLEWRQ----QTEVLSP 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 416 EL-------IRSLEQDLKVAKDvSVRLHHELKTVEEKRAKAEDENETLRQQMieveiskQALQNELERLKESSLKRRSTR 488
Cdd:COG1340 133 EEekelvekIKELEKELEKAKK-ALEKNEKLKELRAELKELRKEAEEIHKKI-------KELAEEAQELHEEMIELYKEA 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 489 -EMYKEKKTFNQQNggmerpGNCRPATKTQRKLAPRRKDDSADLRCQL--QFAKEEAFLMRKKMAKLGREKDELEQELQK 565
Cdd:COG1340 205 dELRKEADELHKEI------VEAQEKADELHEEIIELQKELRELRKELkkLRKKQRALKREKEKEELEEKAEEIFEKLKK 278
|
....
gi 2217316411 566 YKSL 569
Cdd:COG1340 279 GEKL 282
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
149-331 |
6.94e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.87 E-value: 6.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 149 GAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRishtdsssdlsdcpsePLSDEQRLLP 228
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPA----------------RRSPAPEALA 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 229 AASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPE------PPALLAAPLAAGAcPGGRSIP--SGVSGGFAGPGVAE 300
Cdd:PRK12323 435 AARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPvaaaaaAAPARAAPAAAPA-PADDDPPpwEELPPEFASPAPAQ 513
|
170 180 190
....*....|....*....|....*....|....
gi 2217316411 301 DVRGRSPPER---PVPGTPKEPSLGEQSRLVPAA 331
Cdd:PRK12323 514 PDAAPAGWVAesiPDPATADPDDAFETLAPAPAA 547
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
130-313 |
7.10e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.78 E-value: 7.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 130 RRAARVAPAEPLSRA-GKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDS 208
Cdd:PHA03307 742 RRARARASAWDITDAlFSNPSLVPAKLAEALALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTASKRKS 821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 209 SSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSG 288
Cdd:PHA03307 822 RSHTPDGGSESSGPARPPGAAARPPPARSSESSKSKPAAAGGRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAP 901
|
170 180
....*....|....*....|....*
gi 2217316411 289 VSggfAGPGVAEDVRGRSPPERPVP 313
Cdd:PHA03307 902 AP---RPRPAPRVKLGPMPPGGPDP 923
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
345-683 |
7.12e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.78 E-value: 7.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 345 SENDYLKDELDEL-RAEME-EMRDSYLEEdvyQLQELRRELDRANKNCRILQYRLRKAEqkslkvAETGQVDGELIRSLE 422
Cdd:pfam01576 384 SENAELQAELRTLqQAKQDsEHKRKKLEG---QLQELQARLSESERQRAELAEKLSKLQ------SELESVSSLLNEAEG 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 423 QDLKVAKDVSvRLHHELKTV-----EEKRAK---------AEDENETLRQQMIEVEISKQALQNELERLKE--SSLKRR- 485
Cdd:pfam01576 455 KNIKLSKDVS-SLESQLQDTqellqEETRQKlnlstrlrqLEDERNSLQEQLEEEEEAKRNVERQLSTLQAqlSDMKKKl 533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 486 ------------STREMYKEKKTFNQQNGgmERPGNCRPATKTQRKLAPRRKDDSADLRCQLQFA-----KEEAF---LM 545
Cdd:pfam01576 534 eedagtlealeeGKKRLQRELEALTQQLE--EKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVsnlekKQKKFdqmLA 611
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 546 RKKM--AKLGREKDELEQElqkykslygdvdsplptgeaggppsTREAELK-LRLKLVEEEANilgRKIVELEVENRGLK 622
Cdd:pfam01576 612 EEKAisARYAEERDRAEAE-------------------------AREKETRaLSLARALEEAL---EAKEELERTNKQLR 663
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316411 623 AEMEDMRGQQEREGpgrdhapsiptspfgdslESSTELRRHLQFVEEEAELLRRSISEIED 683
Cdd:pfam01576 664 AEMEDLVSSKDDVG------------------KNVHELERSKRALEQQVEEMKTQLEELED 706
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
349-570 |
7.42e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.62 E-value: 7.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 349 YLKDELDELRAEMEEMRDsYLEEdvyQLQELRRELDRANKncRILQYRlrkAEQKSLKVAETGQVDGELIRSLEQDLKVA 428
Cdd:COG3206 161 YLEQNLELRREEARKALE-FLEE---QLPELRKELEEAEA--ALEEFR---QKNGLVDLSEEAKLLLQQLSELESQLAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 429 KDVSVRLHHELKTVEEKRAKAEDEN---------ETLRQQMIEVEiskQALQNELERLKESSLKRRSTREMYKEKKTFNQ 499
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALpellqspviQQLRAQLAELE---AELAELSARYTPNHPDVIALRAQIAALRAQLQ 308
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316411 500 QnggmeRPGNCRPATKTQRKLAPRRKddsADLRCQLQFAKEEAflmrKKMAKLGREKDELEQELQKYKSLY 570
Cdd:COG3206 309 Q-----EAQRILASLEAELEALQARE---ASLQAQLAQLEARL----AELPELEAELRRLEREVEVARELY 367
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
345-634 |
1.12e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 43.96 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 345 SENDYLKDELDELRAEMEEMRDSYLEEDVYQLQE---LRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSL 421
Cdd:pfam05557 2 AELIESKARLSQLQNEKKQMELEHKRARIELEKKasaLKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 422 EQDL---------KVAKDVSVR-LHHELKT-VEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREM 490
Cdd:pfam05557 82 KKYLealnkklneKESQLADAReVISCLKNeLSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQ 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 491 YKEKKTFNQQNGGMER-------------PGNCRPAT--KTQRKLAPRR----------------KDDSADLRCQLQfaK 539
Cdd:pfam05557 162 QSSLAEAEQRIKELEFeiqsqeqdseivkNSKSELARipELEKELERLRehnkhlnenienklllKEEVEDLKRKLE--R 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 540 EEAflMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPP----STREAELKLRLKLVEEEANILGRKIVELE 615
Cdd:pfam05557 240 EEK--YREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRieqlQQREIVLKEENSSLTSSARQLEKARRELE 317
|
330
....*....|....*....
gi 2217316411 616 VENRGLKAEMEDMRGQQER 634
Cdd:pfam05557 318 QELAQYLKKIEDLNKKLKR 336
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
362-697 |
1.15e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.90 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 362 EEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVD--GELIRSLEQDLKVakdvsvrlhHEL 439
Cdd:PRK03918 447 EEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKelAEQLKELEEKLKK---------YNL 517
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 440 KTVEEKrakaEDENETLRQQMIEVEISKQALQNELERLKEssLKRRST------REMYKEKKTFNQQNGGM--------- 504
Cdd:PRK03918 518 EELEKK----AEEYEKLKEKLIKLKGEIKSLKKELEKLEE--LKKKLAelekklDELEEELAELLKELEELgfesveele 591
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 505 ERPGNCRPATKTQRKLAPRRKDDSADLRcQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDvdsplptgEAGG 584
Cdd:PRK03918 592 ERLKELEPFYNEYLELKDAEKELEREEK-ELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE--------EEYE 662
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 585 PPSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERegpgrdhapsipTSPFGDSLESSTELRRhl 664
Cdd:PRK03918 663 ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKE------------LEKLEKALERVEELRE-- 728
|
330 340 350
....*....|....*....|....*....|...
gi 2217316411 665 QFVEEEAELLRRSISEIEDHNRQLTHELSKFKF 697
Cdd:PRK03918 729 KVKKYKALLKERALSKVGEIASEIFEELTEGKY 761
|
|
| DUF4201 |
pfam13870 |
Domain of unknown function (DUF4201); This is a family of coiled-coil proteins from eukaryotes. ... |
376-507 |
1.16e-03 |
|
Domain of unknown function (DUF4201); This is a family of coiled-coil proteins from eukaryotes. The function is not known.
Pssm-ID: 464008 [Multi-domain] Cd Length: 177 Bit Score: 41.82 E-value: 1.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 376 LQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQ----VD-----------GELIRSLEQDLKVAKDVSVRLHHELK 440
Cdd:pfam13870 1 MRAKRNELSKLRLELITLKHTLAKIQEKLEQKEELGEgltmIDflqlqienqalNEKIEERNKELKRLKLKVTNTVHALT 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217316411 441 TVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRstremyKEKKTFNQQNGGMERP 507
Cdd:pfam13870 81 HLKEKLHFLSAELSRLKKELRERQELLAKLRKELYRVKLERDKLR------KQNKKLRQQGGLLHVP 141
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
110-262 |
1.71e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 43.55 E-value: 1.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 110 KPPPGAGaraaggakaalgsrrAARVAPAEPLSRAGKP-PGAEPPSAAAKGRKAKrgsRAPPARTVGPPTPAARI-PAVT 187
Cdd:PRK14951 365 KPAAAAE---------------AAAPAEKKTPARPEAAaPAAAPVAQAAAAPAPA---AAPAAAASAPAAPPAAApPAPV 426
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217316411 188 LAVTSVAGSPARcsriSHTDSSSDLSDCPSEPLSDEQRLLPAAssdAESGTGSSDREPPRGAPTPSPAARGAPPG 262
Cdd:PRK14951 427 AAPAAAAPAAAP----AAAPAAVALAPAPPAQAAPETVAIPVR---VAPEPAVASAAPAPAAAPAAARLTPTEEG 494
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
348-740 |
1.72e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 43.35 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 348 DYLKDELDELRAEMEEMrdSYLEEDVY----QLQELRRELDRANKNCRILqyrLRKAEQKSlkvAETGQVDGELI--RSL 421
Cdd:PRK01156 169 DKLKDVIDMLRAEISNI--DYLEEKLKssnlELENIKKQIADDEKSHSIT---LKEIERLS---IEYNNAMDDYNnlKSA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 422 EQDLKVAKDVSVRLHHELKTVEEKRAKAEDENetlrqqmieVEISkqALQNELERLKESSL--KRRSTREMYKEKKTFNQ 499
Cdd:PRK01156 241 LNELSSLEDMKNRYESEIKTAESDLSMELEKN---------NYYK--ELEERHMKIINDPVykNRNYINDYFKYKNDIEN 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 500 QNGGMER-PGNCRPATKTQRKLAPRRKDDSadlrcqlQFAKeeaflMRKKMAKLGREKDELEQELQKYKSLYGDVDS--- 575
Cdd:PRK01156 310 KKQILSNiDAEINKYHAIIKKLSVLQKDYN-------DYIK-----KKSRYDDLNNQILELEGYEMDYNSYLKSIESlkk 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 576 ------------PLPTGEAGGPPSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGpGRDHAP 643
Cdd:PRK01156 378 kieeyskniermSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLN-GQSVCP 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 644 SIPTSpFGDslESSTELRRH----LQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPPREpgwlgegASPGAGGGAP 719
Cdd:PRK01156 457 VCGTT-LGE--EKSNHIINHynekKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINK-------SINEYNKIES 526
|
410 420
....*....|....*....|.
gi 2217316411 720 LQEELKSARLQISELSGKVLK 740
Cdd:PRK01156 527 ARADLEDIKIKINELKDKHDK 547
|
|
| Rootletin |
pfam15035 |
Ciliary rootlet component, centrosome cohesion; |
391-493 |
1.72e-03 |
|
Ciliary rootlet component, centrosome cohesion;
Pssm-ID: 464459 [Multi-domain] Cd Length: 190 Bit Score: 41.56 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 391 RILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDL-----KVAKDVSVRLHHELKTVEEKRAKAED---ENETLRQQMIE 462
Cdd:pfam15035 24 KVLQYKKRCSELEQQLLEKTSELEKTELLLRKLTLeprlqRLEREHSADLEEALIRLEEERQRSESlsqVNSLLREQLEQ 103
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2217316411 463 VEISKQALQNELERL-------------KESSLKRRstREMYKE 493
Cdd:pfam15035 104 ASRANEALREDLQKLtndwerareeleqKESEWRKE--EEAFNE 145
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
350-487 |
2.31e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.08 E-value: 2.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKncrilqyRLRKAEQKSLKVAETgqvDGELIRSLEQDLKvak 429
Cdd:COG3206 268 LRAQLAELEAELAELSARYTPNHP-DVIALRAQIAALRA-------QLQQEAQRILASLEA---ELEALQAREASLQ--- 333
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316411 430 dvsvrlhhelKTVEEKRAKAEDENETLRQQMI---EVEISKQALQNELERLKESSLKRRST 487
Cdd:COG3206 334 ----------AQLAQLEARLAELPELEAELRRlerEVEVARELYESLLQRLEEARLAEALT 384
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
416-696 |
2.38e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.13 E-value: 2.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 416 ELIRSLEQDLKVAKDVSVRLhhelKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESslkRRSTREMYKEKK 495
Cdd:PRK03918 176 RRIERLEKFIKRTENIEELI----KEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL---KEEIEELEKELE 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 496 TFNQQNGGME-RPGNCRPATKTQRKLAPRRKDDSADLRcQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVD 574
Cdd:PRK03918 249 SLEGSKRKLEeKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIE 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 575 SPLPTGEAggpPSTREAELKLRLKLVEEEANILGRKIVELEVenrgLKAEMEDMRGQQEREGPgrdhapsiptspfgdsl 654
Cdd:PRK03918 328 ERIKELEE---KEERLEELKKKLKELEKRLEELEERHELYEE----AKAKKEELERLKKRLTG----------------- 383
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2217316411 655 ESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFK 696
Cdd:PRK03918 384 LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELK 425
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
340-633 |
2.60e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.83 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 340 MEELRSENDYLKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKsLKVAETGQVDGELIR 419
Cdd:COG4717 165 LEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE-LEQLENELEAAALEE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 420 SLEQDLKVAKDVSVRLHHE----------------------------LKTVEEKRAKAEDENETLRQQMIEvEISKQALQ 471
Cdd:COG4717 244 RLKEARLLLLIAAALLALLglggsllsliltiagvlflvlgllallfLLLAREKASLGKEAEELQALPALE-ELEEEELE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 472 NELERLK-ESSLKRRSTREMYKEKKTFNQQNGGMERpgncrpaTKTQRKLAPRRKDDSADLRcQLQFAKEEAFLMRkkmA 550
Cdd:COG4717 323 ELLAALGlPPDLSPEELLELLDRIEELQELLREAEE-------LEEELQLEELEQEIAALLA-EAGVEDEEELRAA---L 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 551 KLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPpstrEAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRG 630
Cdd:COG4717 392 EQAEEYQELKEELEELEEQLEELLGELEELLEALD----EEELEEELEELEEELEELEEELEELREELAELEAELEQLEE 467
|
...
gi 2217316411 631 QQE 633
Cdd:COG4717 468 DGE 470
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
12-185 |
2.68e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.94 E-value: 2.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 12 APDAKLQPPGQHHRHHHLHPV--AERRRLHRAPSPARPFLKDL----HARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAP 85
Cdd:PRK12323 391 APAAAAPAPAAPPAAPAAAPAaaAAARAVAAAPARRSPAPEALaaarQASARGPGGAPAPAPAPAAAPAAAARPAAAGPR 470
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 86 PSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRagkPPGAEPPSAAAKGRKAKRG 165
Cdd:PRK12323 471 PVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPD---PATADPDDAFETLAPAPAA 547
|
170 180
....*....|....*....|
gi 2217316411 166 SRAPPARTVGPPTPAARIPA 185
Cdd:PRK12323 548 APAPRAAAATEPVVAPRPPR 567
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1197-1345 |
2.71e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.12 E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 1197 KQVVENQQ-LFSAFKALLEDFRAELREDERARLRLQ---QQYASDKAAWDVEWAVLKCRLEQLEEKTENKLGELGSSAES 1272
Cdd:TIGR02168 788 EAQIEQLKeELKALREALDELRAELTLLNEEAANLRerlESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217316411 1273 KGALKKEREVHQKLLADSHSLVMDLRwqihhseknwnrekvELLDRLDRDRQEWERQKKEFLWRIEQLQKENS 1345
Cdd:TIGR02168 868 IEELESELEALLNERASLEEALALLR---------------SELEELSEELRELESKRSELRRELEELREKLA 925
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
31-156 |
2.78e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.78 E-value: 2.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 31 PVAERRRLHRaPSPARPFLKDLHARPAAPGPAVPSSGrapapaaprspnlAGKAPPSPGSLAAPGRLSRRSGGVPGAKDK 110
Cdd:PRK14951 374 APAEKKTPAR-PEAAAPAAAPVAQAAAAPAPAAAPAA-------------AASAPAAPPAAAPPAPVAAPAAAAPAAAPA 439
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2217316411 111 PPPGAGARAAGGAKAALGSRRA--ARVAPAEPLSRAGKPPGAEPPSAA 156
Cdd:PRK14951 440 AAPAAVALAPAPPAQAAPETVAipVRVAPEPAVASAAPAPAAAPAAAR 487
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
374-577 |
3.77e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 3.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 374 YQLQELRRELDRANKNCRILQYRLRKAEQKslkvaetgqvdgelIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDEN 453
Cdd:COG1579 10 LDLQELDSELDRLEHRLKELPAELAELEDE--------------LAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 454 ETLRQQMIEVEISK--QALQNELERLKesslKRRSTREmykekktfNQQNGGMERpgncrpATKTQRKLApRRKDDSADL 531
Cdd:COG1579 76 KKYEEQLGNVRNNKeyEALQKEIESLK----RRISDLE--------DEILELMER------IEELEEELA-ELEAELAEL 136
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2217316411 532 RCQLQFAKEEAflmRKKMAKLGREKDELEQELQKYKSlygDVDSPL 577
Cdd:COG1579 137 EAELEEKKAEL---DEELAELEAELEELEAEREELAA---KIPPEL 176
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
526-754 |
4.28e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 4.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 526 DDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYkslygdvdsplptgeaggppSTREAELKLRLKLVEEEAN 605
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL--------------------ERRIAALARRIRALEQELA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 606 ILGRKIVELEVENRGLKAEMEDMRGQQER-----EGPGRDHAPSIPTSP--FGDSLESSTELRRHLQFVEEEAELLRRSI 678
Cdd:COG4942 80 ALEAELAELEKEIAELRAELEAQKEELAEllralYRLGRQPPLALLLSPedFLDAVRRLQYLKYLAPARREQAEELRADL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217316411 679 SEIEDHNRQLTHELSKfkfepprepgwLGEGASPGAGGGAPLQEELKSARLQISELSGKVLKLQHENHALLSNIQR 754
Cdd:COG4942 160 AELAALRAELEAERAE-----------LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
356-688 |
4.80e-03 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 42.05 E-value: 4.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 356 ELRAEMEEMRDSyLEEDVYQLQELRRELDRANKNCRILQYRLRKaeqkslKVAETgQVDGELIRSLEQDLKVAKDVSVRL 435
Cdd:pfam07111 321 QLKAQDLEHRDS-VKQLRGQVAELQEQVTSQSQEQAILQRALQD------KAAEV-EVERMSAKGLQMELSRAQEARRRQ 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 436 HHELKTVEEKR----AKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQQNGGMERPGNCR 511
Cdd:pfam07111 393 QQQTASAEEQLkfvvNAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVHTIKGLMARKVALAQLRQESCPPPPPA 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 512 PATKTQRKLAPRR-KDDSADLRCQLQF-----------AKEEAFLMRKKMAKLGREkdeLEQELQKYKSLYGDVDSPLPT 579
Cdd:pfam07111 473 PPVDADLSLELEQlREERNRLDAELQLsahliqqevgrAREQGEAERQQLSEVAQQ---LEQELQRAQESLASVGQQLEV 549
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 580 GEAGGPPSTREAElKLRLKLVEEEaNILGRKIVE--LEVENRgLKAEMEDM--RGQQERegpgRDHAPSIPT-----SPF 650
Cdd:pfam07111 550 ARQGQQESTEEAA-SLRQELTQQQ-EIYGQALQEkvAEVETR-LREQLSDTkrRLNEAR----REQAKAVVSlrqiqHRA 622
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 2217316411 651 GDSLESSTELRR-HLQFVEEEAELLRRSISEIE-DHNRQL 688
Cdd:pfam07111 623 TQEKERNQELRRlQDEARKEEGQRLARRVQELErDKNLML 662
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
7-311 |
4.82e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.23 E-value: 4.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 7 PAGGGAPD------AKLQPPGQHHRHHHLHPVAERRRLHRAPsparpflkdLHARPAAPGPAVPSSGRAPAPAAPRSPNL 80
Cdd:PHA03247 206 PSGPGPAApadltaAALHLYGASETYLQDEPFVERRVVISHP---------LRGDIAAPAPPPVVGEGADRAPETARGAT 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 81 AGKAPPSPGSLAAPGRLSRRS-----GGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKP-------- 147
Cdd:PHA03247 277 GPPPPPEAAAPNGAAAPPDGVwgaalAGAPLALPAPPDPPPPAPAGDAEEEDDEDGAMEVVSPLPRPRQHYPlgfpkrrr 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 148 PGAEPPSAA---AKGRKAKRgsRAPPARTVGPPTPAARIPavtlavtsVAGSPArcsrishtdssSDLSDCPSEPlsdeq 224
Cdd:PHA03247 357 PTWTPPSSLedlSAGRHHPK--RASLPTRKRRSARHAATP--------FARGPG-----------GDDQTRPAAP----- 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 225 rlLPAASSDAESGTGSSDREPPRGAPTPSP-AARGAPPGSPeppallaaplAAGACPGGRSIPSGVSGGFAGPGVAEDVR 303
Cdd:PHA03247 411 --VPASVPTPAPTPVPASAPPPPATPLPSAePGSDDGPAPP----------PERQPPAPATEPAPDDPDDATRKALDALR 478
|
....*...
gi 2217316411 304 GRSPPERP 311
Cdd:PHA03247 479 ERRPPEPP 486
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
36-184 |
5.46e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 41.98 E-value: 5.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 36 RRLHRAPSPARPflkdlhaRPAAPGPAVPSSGRAPAPAAPrspnlAGKAPPSPGSLAAPGRLsRRSGGVPGAKdkPPPGA 115
Cdd:PHA03378 685 LPIQWAPGTMQP-------PPRAPTPMRPPAAPPGRAQRP-----AAATGRARPPAAAPGRA-RPPAAAPGRA--RPPAA 749
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217316411 116 GARAAGGAKAALGSRRAARVAPaeplsraGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIP 184
Cdd:PHA03378 750 APGRARPPAAAPGRARPPAAAP-------GAPTPQPPPQAPPAPQQRPRGAPTPQPPPQAGPTSMQLMP 811
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
392-624 |
6.18e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.68 E-value: 6.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 392 ILQYRLRKAEQKSLKV-AETGQVDGELIRSLEQDLKvakdvsvrlhhELKTVEEKRAKAEDENETLRQQMIEVEISKQAL 470
Cdd:COG4717 46 MLLERLEKEADELFKPqGRKPELNLKELKELEEELK-----------EAEEKEEEYAELQEELEELEEELEELEAELEEL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 471 QNELERLKesslKRRSTREMYKEKKTFNQQ-NGGMERpgncrpATKTQRKLAPRRkddsaDLRCQLQFAKEEAFLMRKKM 549
Cdd:COG4717 115 REELEKLE----KLLQLLPLYQELEALEAElAELPER------LEELEERLEELR-----ELEEELEELEAELAELQEEL 179
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217316411 550 AKLGREKD-ELEQELQKYKSLYGDVDSplptgeaggppstREAELKLRLKLVEEEANILGRKIVELEVENRGLKAE 624
Cdd:COG4717 180 EELLEQLSlATEEELQDLAEELEELQQ-------------RLAELEEELEEAQEELEELEEELEQLENELEAAALE 242
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
350-635 |
7.53e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 40.66 E-value: 7.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 350 LKDELDELRAEMEEMRDSyLEEDVYQLQELRRELDraNKNCRILQYRLRKAEQKSLKvaetgqvdGELIRSLeQDLKVAK 429
Cdd:COG1340 13 LEEKIEELREEIEELKEK-RDELNEELKELAEKRD--ELNAQVKELREEAQELREKR--------DELNEKV-KELKEER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 430 DvsvrlhhELKT-VEEKRAKAEDENEtLRQQMIEVEISKQALQNELERLKESSLKRRSTREmyKEKKTFNQqnggmerpg 508
Cdd:COG1340 81 D-------ELNEkLNELREELDELRK-ELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPE--EEKELVEK--------- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 509 ncrpATKTQRKLapRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYK----SLYGDVDSplptgeagg 584
Cdd:COG1340 142 ----IKELEKEL--EKAKKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHeemiELYKEADE--------- 206
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 2217316411 585 ppSTREA--------ELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERE 635
Cdd:COG1340 207 --LRKEAdelhkeivEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKE 263
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
344-695 |
7.58e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.16 E-value: 7.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 344 RSENDYLKDELDELRAEMEEmrdsyLEEDVYQLQELRRELDranKNCRILQ--YRLRKAEQKSLKVAETGQvdGELIRSL 421
Cdd:TIGR04523 376 KKENQSYKQEIKNLESQIND-----LESKIQNQEKLNQQKD---EQIKKLQqeKELLEKEIERLKETIIKN--NSEIKDL 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 422 EQDLKVAKdvsvrlhhelKTVEEKRAKAEDENETLRQQMIEVEISKQALQN---ELERlKESSLKR--RSTREMYKEKKT 496
Cdd:TIGR04523 446 TNQDSVKE----------LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQkqkELKS-KEKELKKlnEEKKELEEKVKD 514
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 497 FNQQNGGMerpgncrpaTKTQRKLAPRRKDDSADLRcqlqfAKEEAFL---MRKKMAKLGREKDELEQELQKYKSLYGDV 573
Cdd:TIGR04523 515 LTKKISSL---------KEKIEKLESEKKEKESKIS-----DLEDELNkddFELKKENLEKEIDEKNKEIEELKQTQKSL 580
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 574 DSplptgeaggppstREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERegpgrdhapsipTSPFGDS 653
Cdd:TIGR04523 581 KK-------------KQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEK------------LSSIIKN 635
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 2217316411 654 LESSTE-LRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKF 695
Cdd:TIGR04523 636 IKSKKNkLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDI 678
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
56-329 |
9.20e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 40.71 E-value: 9.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 56 PAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRS---------GGVP---GAKDKPPPGAGARAAGGA 123
Cdd:pfam17823 115 LAAAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAAPRAaiaaasaphAASPaprTAASSTTAASSTTAASSA 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 124 KAALGSRRAARVAPAEPLSRAGKPPGAepPSAAAKgrKAKRGSRAPPART----VGPPTPA--ARIPAVTLAVTSVAGSP 197
Cdd:pfam17823 195 PTTAASSAPATLTPARGISTAATATGH--PAAGTA--LAAVGNSSPAAGTvtaaVGTVTPAalATLAAAAGTVASAAGTI 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316411 198 ARCSRISHTDSSSdlSDCPSEPLSDEqrllPAASSDAES-GTGS--SDREP---PRGAPTPSPAARGAPPGSPEPPALLA 271
Cdd:pfam17823 271 NMGDPHARRLSPA--KHMPSDTMARN----PAAPMGAQAqGPIIqvSTDQPvhnTAGEPTPSPSNTTLEPNTPKSVASTN 344
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2217316411 272 APLAAGACPGGRSiPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSLGEQSRLVP 329
Cdd:pfam17823 345 LAVVTTTKAQAKE-PSASPVPVLHTSMIPEVEATSPTTQPSPLLPTQGAAGPGILLAP 401
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