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Conserved domains on  [gi|1338807362|ref|XP_023701154|]
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NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [Paramormyrops kingsleyae]

Protein Classification

NuoI/complex I 23 kDa subunit family protein( domain architecture ID 11481829)

NuoI/complex I 23 kDa subunit family protein such as bacterial NADH-quinone oxidoreductase subunit I (NuoI), which is part of the connecting domain of complex I of the respiratory chain that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

EC:  7.1.1.-
Gene Ontology:  GO:0016651|GO:0051539|GO:0016020
PubMed:  23417064|33957129|24059520

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
95-251 6.61e-94

NADH-quinone oxidoreductase subunit NuoI;


:

Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 272.91  E-value: 6.61e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362  95 RAAQTLLWTELFRGLGMTMSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPR 174
Cdd:PRK05888    3 QYLKSMLLKELLKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAER 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338807362 175 ADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR 251
Cdd:PRK05888   83 EDGRRRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGDRVEREIAPGKAADANYR 159
 
Name Accession Description Interval E-value
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
95-251 6.61e-94

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 272.91  E-value: 6.61e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362  95 RAAQTLLWTELFRGLGMTMSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPR 174
Cdd:PRK05888    3 QYLKSMLLKELLKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAER 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338807362 175 ADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR 251
Cdd:PRK05888   83 EDGRRRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGDRVEREIAPGKAADANYR 159
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 108-229 1.01e-62

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 192.25  E-value: 1.01e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 108 GLGMTMSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDID 187
Cdd:TIGR01971   1 GLGLTLKYFFSKPVTVQYPEEKLYLPPRFRGRIVLTRDPNGEEKCIGCTLCAAVCPADAIRVVPAEGEDGKRRLKFYEIN 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1338807362 188 MTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKL 229
Cdd:TIGR01971  81 FGRCIFCGLCEEACPTDAIVLTPEFELATYTRSDLVYGKEDL 122
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 149-221 3.81e-22

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 86.34  E-value: 3.81e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEpradgsRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPnFEFSTETHEE 221
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDG------EPGKVYVIDPDKCIGCGLCVEVCPTGAISMTP-FELAVEDREE 66
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 149-207 1.28e-16

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 73.59  E-value: 1.28e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRADgsrrttrydIDMTKCIYCGFCQEACPVDAIV 207
Cdd:cd10549    77 EEKCIGCGLCVKVCPVDAITLEDELEIV---------IDKEKCIGCGICAEVCPVNAIK 126
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 152-205 1.87e-12

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 60.23  E-value: 1.87e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1338807362 152 CIACKLCEAICPAQAITIEAEPRADGsrrTTRYDIDMTKCIYCGFCQEACPVDA 205
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKG---TKTVVIDPERCVGCGACVAVCPTGA 51
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 116-206 2.04e-06

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 47.55  E-value: 2.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 116 LFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAE-PRADGsrrttrydidmtKCIYC 194
Cdd:NF038196  151 GPEKKKGFIPRLLSKLVNPLFYKFKVKDKKFHVTDKCIGCGICAKVCPVNNIEMEDGkPVWGH------------NCTHC 218

                          90
                  ....*....|..
gi 1338807362 195 GFCQEACPVDAI 206
Cdd:NF038196  219 LACIHRCPKEAI 230
 
Name Accession Description Interval E-value
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
95-251 6.61e-94

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 272.91  E-value: 6.61e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362  95 RAAQTLLWTELFRGLGMTMSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPR 174
Cdd:PRK05888    3 QYLKSMLLKELLKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAER 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338807362 175 ADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR 251
Cdd:PRK05888   83 EDGRRRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGDRVEREIAPGKAADANYR 159
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 108-229 1.01e-62

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 192.25  E-value: 1.01e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 108 GLGMTMSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDID 187
Cdd:TIGR01971   1 GLGLTLKYFFSKPVTVQYPEEKLYLPPRFRGRIVLTRDPNGEEKCIGCTLCAAVCPADAIRVVPAEGEDGKRRLKFYEIN 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1338807362 188 MTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKL 229
Cdd:TIGR01971  81 FGRCIFCGLCEEACPTDAIVLTPEFELATYTRSDLVYGKEDL 122
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 149-221 3.81e-22

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 86.34  E-value: 3.81e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEpradgsRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPnFEFSTETHEE 221
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDG------EPGKVYVIDPDKCIGCGLCVEVCPTGAISMTP-FELAVEDREE 66
ndhI CHL00014
NADH dehydrogenase subunit I
 107-226 1.47e-17

NADH dehydrogenase subunit I


Pssm-ID: 214334 [Multi-domain]  Cd Length: 167  Bit Score: 77.49  E-value: 1.47e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 107 RGLGMTMSYLFREPATINYPFEKGPLSPRFRGehalrRYPSGEERCIACKLCEAICPAQAITIEAEPRAD-GSRRTTRYD 185
Cdd:CHL00014   21 QGFMITLSHANRLPVTIQYPYEKLITSERFRG-----RIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDiRKKRLLNYS 95

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1338807362 186 IDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNK 226
Cdd:CHL00014   96 IDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQ 136
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 120-227 5.76e-17

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 76.22  E-value: 5.76e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 120 PATINYPFEKGPLSPRFRG--EHALrrypsgeERCIACKLCEAICPAQAITIEAepraDGSRRTTRYDIDMTKCIYCGFC 197
Cdd:PRK12387   13 TATSSYPLEPIAVDKNFRGkpEYNP-------QQCIGCAACVNACPSNALTVET----DLATGELAWEFNLGRCIFCGRC 81

                          90       100       110
                  ....*....|....*....|....*....|
gi 1338807362 198 QEACPVDAIVEGPNFEFSTETHEELLYNKE 227
Cdd:PRK12387   82 EEVCPTAAIKLSQEFELAVWKKEDLLQQSE 111
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 149-207 1.28e-16

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 73.59  E-value: 1.28e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRADgsrrttrydIDMTKCIYCGFCQEACPVDAIV 207
Cdd:cd10549    77 EEKCIGCGLCVKVCPVDAITLEDELEIV---------IDKEKCIGCGICAEVCPVNAIK 126
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 121-226 6.31e-15

hydrogenase 4 subunit H; Validated


Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 70.55  E-value: 6.31e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 121 ATINYPFEKGPLSPRFRGEHALrrypsGEERCIACKLCEAICPAQAITIEAepraDGSRRTTRYDIDMTKCIYCGFCQEA 200
Cdd:PRK08222   14 ATVKYPFAPLEVSPGFRGKPDL-----MPSQCIACGACTCACPANALTIQT----DDQQNSRTWQLYLGRCIYCGRCEEV 84

                          90       100
                  ....*....|....*....|....*.
gi 1338807362 201 CPVDAIVEGPNFEFsTETHEELLYNK 226
Cdd:PRK08222   85 CPTRAIQLTNNFEL-TVTNKADLYTR 109
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
140-213 6.74e-15

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 67.45  E-value: 6.74e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1338807362 140 HALRRYPSGEERCIACKLCEAICPAQAITIEAEPradgsrrttrYDIDMTKCIYCGFCQEACPVDAIVEGPNFE 213
Cdd:COG2768     1 HSLGKPYVDEEKCIGCGACVKVCPVGAISIEDGK----------AVIDPEKCIGCGACIEVCPVGAIKIEWEED 64
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 149-228 7.58e-15

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 68.96  E-value: 7.58e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 149 EERCIACKLCEAICPAQAITIEaepraDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEK 228
Cdd:cd10549     5 PEKCIGCGICVKACPTDAIELG-----PNGAIARGPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKEAEIDEEK 79
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 149-214 1.44e-14

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 66.61  E-value: 1.44e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEpradgsrrttRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEF 214
Cdd:COG2221    14 EEKCIGCGLCVAVCPTGAISLDDG----------KLVIDEEKCIGCGACIRVCPTGAIKGEKPKKF 69
PRK13984 PRK13984
putative oxidoreductase; Provisional
 115-201 2.96e-13

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 68.64  E-value: 2.96e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 115 YLFREPATINYPFEKGPLSPRFRGEHAlrrypSGEERCIACKLCEAICPAQAIT---IEAEPRADGSrRTTRYDIDMTKC 191
Cdd:PRK13984   15 FLFRKPVTIKVPNVKREAAERYRGFHI-----NDWEKCIGCGTCSKICPTDAITmveVPDLPQEYGK-KPQRPVIDYGRC 88

                          90
                  ....*....|
gi 1338807362 192 IYCGFCQEAC 201
Cdd:PRK13984   89 SFCALCVDIC 98
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 149-206 4.30e-13

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 64.34  E-value: 4.30e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 149 EERCIACKLCEAICPAQAITIEaEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 206
Cdd:cd10549    39 EDKCVFCGACVEVCPTGAIELT-PEGKEYVPKEKEAEIDEEKCIGCGLCVKVCPVDAI 95
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 149-207 5.68e-13

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 62.37  E-value: 5.68e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRAdgsrrttrydIDMTKCIYCGFCQEACPVDAIV 207
Cdd:COG4231    21 EDKCTGCGACVKVCPADAIEEGDGKAV----------IDPDLCIGCGSCVQVCPVDAIK 69
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 152-205 1.87e-12

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 60.23  E-value: 1.87e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1338807362 152 CIACKLCEAICPAQAITIEAEPRADGsrrTTRYDIDMTKCIYCGFCQEACPVDA 205
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKG---TKTVVIDPERCVGCGACVAVCPTGA 51
NapF COG1145
Ferredoxin [Energy production and conversion];
149-206 2.37e-12

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 64.74  E-value: 2.37e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEpradgsrrTTRYDIDMTKCIYCGFCQEACPVDAI 206
Cdd:COG1145   181 AEKCIGCGLCVKVCPTGAIRLKDG--------KPQIVVDPDKCIGCGACVKVCPVGAI 230
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 149-207 4.34e-12

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 60.45  E-value: 4.34e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEpradgsrrtTRYDIDMTKCIYCGFCQEACPVDAIV 207
Cdd:COG1144    29 EDKCIGCGLCWIVCPDGAIRVDDG---------KYYGIDYDYCKGCGICAEVCPVKAIE 78
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 149-210 7.85e-12

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 58.97  E-value: 7.85e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEpradgsrrtTRYDIDMTKCIYCGFCQEACPVDAIVEGP 210
Cdd:COG1149    10 EEKCIGCGLCVEVCPEGAIKLDDG---------GAPVVDPDLCTGCGACVGVCPTGAITLEE 62
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 149-206 2.05e-11

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 58.18  E-value: 2.05e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEpradgSRRTTRYDIDmtKCIYCGFCQEACPVDAI 206
Cdd:COG1146     7 TDKCIGCGACVEVCPVDVLELDEE-----GKKALVINPE--ECIGCGACELVCPVGAI 57
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 109-217 1.98e-10

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 56.77  E-value: 1.98e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 109 LGMTMSYLFREPATINYP-FEKGPLSPRFRGEHALRRypsgeERCIACKLCEAICPAQAITIEAEPRadgsrrttRYDID 187
Cdd:PRK08348    5 LPTVLRNLFKKPATNLFPaTEPVPVPEDFRGKILYDV-----DKCVGCRMCVTVCPAGVFVYLPEIR--------KVALW 71

                          90       100       110
                  ....*....|....*....|....*....|
gi 1338807362 188 MTKCIYCGFCQEACPVDAIVEGPNFEFSTE 217
Cdd:PRK08348   72 TGRCVFCGQCVDVCPTGALQMSDDFLLASY 101
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
149-208 1.29e-09

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 57.73  E-value: 1.29e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 149 EERCIACKLCEAICPAQAITIEaepraDGSRRttrydIDMTKCIYCGFCQEACPVDAIVE 208
Cdd:COG4624    90 KEKCKNCYPCVRACPVKAIKVD-----DGKAE-----IDEEKCISCGQCVAVCPFGAITE 139
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
152-208 1.72e-09

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 56.87  E-value: 1.72e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1338807362 152 CIACKLCEAICPAQAITIEaepradgsrrTTRYDIDMTKCIYCGFCQEACPVDAIVE 208
Cdd:PRK07118  215 CIGCGKCVKACPAGAITME----------NNLAVIDQEKCTSCGKCVEKCPTKAIRI 261
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
149-206 1.93e-09

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 57.56  E-value: 1.93e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRAdgsrrttryDIDMTKCIYCGFCQEACPVDAI 206
Cdd:COG1148   495 PEKCTGCGRCVEVCPYGAISIDEKGVA---------EVNPALCKGCGTCAAACPSGAI 543
Fer4_9 pfam13187
4Fe-4S dicluster domain;
151-206 5.67e-09

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 51.02  E-value: 5.67e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1338807362 151 RCIACKLCEAICPAQAITIeaepraDGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 206
Cdd:pfam13187   1 KCTGCGACVAACPAGAIVP------DLVGQTIRGDIAGLACIGCGACVDACPRGAI 50
PRK06273 PRK06273
ferredoxin; Provisional
 149-203 2.79e-08

ferredoxin; Provisional


Pssm-ID: 235764 [Multi-domain]  Cd Length: 165  Bit Score: 52.02  E-value: 2.79e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 149 EERCIACKLCEAICPAQAIT-IEAEPR--ADGSRRTTRYDIDMTKCIYCGFCQEACPV 203
Cdd:PRK06273   48 EELCIGCGGCANVCPTKAIEmIPVEPVkiTEGYVKTKIPKIDYEKCVYCLYCHDFCPV 105
FeFe_hydrog_B1 TIGR04105
[FeFe] hydrogenase, group B1/B3; See for descriptions of different groups.
 150-208 4.63e-08

[FeFe] hydrogenase, group B1/B3; See for descriptions of different groups.


Pssm-ID: 274983 [Multi-domain]  Cd Length: 462  Bit Score: 52.98  E-value: 4.63e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1338807362 150 ERCIACKLCEAICPAQAIT------IEAEP-RADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVE 208
Cdd:TIGR04105 142 EKCIECGKCKKACPYNAIVeierpcEKACPvGAISSDEDGRAVIDYDKCISCGACMVACPFGAISD 207
PRK14028 PRK14028
pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional
 151-206 1.68e-07

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional


Pssm-ID: 172522 [Multi-domain]  Cd Length: 312  Bit Score: 51.15  E-value: 1.68e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 151 RCIACKLCEAICPAQAItIEAEPRADGSR----RTTRYDIDMTKCIYCGFCQEACPVDAI 206
Cdd:PRK14028  248 KCIMCRKCWLYCPDDAI-IEAWREAEGPRgrkfRMKMIDFDYQYCKGCGVCAEVCPTGAI 306
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 149-206 3.86e-07

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 48.41  E-value: 3.86e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIdMTKCIYCGF------CQEACPVDAI 206
Cdd:cd10554    84 EERCIGCKLCVLACPFGAIEMAPTTVPGVDWERGPRAV-AVKCDLCAGreggpaCVEACPTKAL 146
PRK13795 PRK13795
hypothetical protein; Provisional
 151-203 4.06e-07

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 50.38  E-value: 4.06e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1338807362 151 RCIACKLCEAICPAQAITIEAEPRadgsrrttRYDIDMTKCIYCGFCQEACPV 203
Cdd:PRK13795  582 ECVGCGVCVGACPTGAIRIEEGKR--------KISVDEEKCIHCGKCTEVCPV 626
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 150-215 4.84e-07

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 48.68  E-value: 4.84e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 150 ERCIACKLCEAICPAQAITI-EAEPRADGSRRTTRYDIdMTKCIYC------G---FCQEACPVDAIVEG----PNFEFS 215
Cdd:cd10551    83 DKCIGCRYCMAACPYGARYFnPEEPHEFGEVPVRPKGV-VEKCTFCyhrldeGllpACVEACPTGARIFGdlddPNSEVS 161
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 139-207 7.77e-07

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 47.00  E-value: 7.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 139 EHALRRYPSG-----EERCIACKLCEAICPAQAITIEAEPRadgsrrttrydiDMTKCIYCGF---------CQEACPVD 204
Cdd:cd04410    64 TGAIYKDEDGivlidEDKCIGCGSCVEACPYGAIVFDPEPG------------KAVKCDLCGDrldeglepaCVKACPTG 131


                  ...
gi 1338807362 205 AIV 207
Cdd:cd04410   132 ALT 134
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 153-206 1.01e-06

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 46.85  E-value: 1.01e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1338807362 153 IACKLCEAICPAQAITIEaePRADGSRRTTrydIDMTKCIYCGFCQEACPVDAI 206
Cdd:cd10564    86 VECRSCQDACPTQAIRFR--PRLGGIALPE---LDADACTGCGACVSVCPVGAI 134
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
152-206 1.05e-06

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 46.96  E-value: 1.05e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1338807362 152 CIACKL--CEAICPAQAITieaepradgsRRTTRYDIDMTKCIYCGFCQEACPVDAI 206
Cdd:COG1142    52 CRHCEDapCAEVCPVGAIT----------RDDGAVVVDEEKCIGCGLCVLACPFGAI 98
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
151-206 1.08e-06

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 48.87  E-value: 1.08e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1338807362 151 RCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 206
Cdd:COG4624    53 RCCLCCCCCCRCCVAISCIQVRGIIIIDKRGPSIIRDKEKCKNCYPCVRACPVKAI 108
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
149-207 1.08e-06

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 46.96  E-value: 1.08e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRADGSrrttrydidmTKCIYCGF------CQEACPVDAIV 207
Cdd:COG1142    80 EEKCIGCGLCVLACPFGAITMVGEKSRAVA----------VKCDLCGGreggpaCVEACPTGALR 134
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 152-210 1.09e-06

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 49.10  E-value: 1.09e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1338807362 152 CIACKLCEAICPAQAITIEAEPRadgsrrttRYDIDMTKCIYCGFCQEACPVDAIVEGP 210
Cdd:PRK12771  512 CFECDNCYGACPQDAIIKLGPGR--------RYHFDYDKCTGCHICADVCPCGAIEMGP 562
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
149-206 1.13e-06

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 48.52  E-value: 1.13e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 149 EERCIACKLCEAICPAQAItieaePRaDGSrrttrydIDMTKCIYCGFCQEACPVDAI 206
Cdd:COG0348   209 RGDCIDCGLCVKVCPMGID-----IR-KGE-------INQSECINCGRCIDACPKDAI 253
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 140-207 1.56e-06

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 47.25  E-value: 1.56e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 140 HALRRYPSG-----EERCIACKLCEAICPAQAITIEAEPRAdgsrrttrydidMTKCIYCGF---------CQEACPVDA 205
Cdd:COG0437    75 GATYKREDGivlvdYDKCIGCRYCVAACPYGAPRFNPETGV------------VEKCTFCADrldegllpaCVEACPTGA 142


                  ..
gi 1338807362 206 IV 207
Cdd:COG0437   143 LV 144
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 143-207 1.96e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 46.03  E-value: 1.96e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 143 RRYPSGEERCIACKLCE-----AICPAQAITIEAEpradgsrrTTRYDIDMTKCIYCGFCQEACPVDAIV 207
Cdd:cd10550    37 RFEPEGLDVPVVCRQCEdapcvEACPVGAISRDEE--------TGAVVVDEDKCIGCGMCVEACPFGAIR 98
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 116-206 2.04e-06

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 47.55  E-value: 2.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 116 LFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAE-PRADGsrrttrydidmtKCIYC 194
Cdd:NF038196  151 GPEKKKGFIPRLLSKLVNPLFYKFKVKDKKFHVTDKCIGCGICAKVCPVNNIEMEDGkPVWGH------------NCTHC 218

                          90
                  ....*....|..
gi 1338807362 195 GFCQEACPVDAI 206
Cdd:NF038196  219 LACIHRCPKEAI 230
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 149-207 2.39e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 46.09  E-value: 2.39e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 149 EERCIA------CKLCEAICPAQAITIEAEpraDGSRRTTrydIDMTKCIYCGFCQEACPVD---AIV 207
Cdd:cd16373    90 KDRCLAwqggtdCGVCVEACPTEAIAIVLE---DDVLRPV---VDEDKCVGCGLCEYVCPVEppkAIV 151
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 149-202 3.74e-06

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 43.39  E-value: 3.74e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRADGSRRTtryDIDMTKCIYCGFCQEACP 202
Cdd:pfam13237   6 PDKCIGCGRCTAACPAGLTRVGAIVERLEGEAV---RIGVWKCIGCGACVEACP 56
Fer4_16 pfam13484
4Fe-4S double cluster binding domain;
152-202 4.71e-06

4Fe-4S double cluster binding domain;


Pssm-ID: 463893 [Multi-domain]  Cd Length: 65  Bit Score: 43.25  E-value: 4.71e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338807362 152 CIACKLCEAICPAQAIT---IEAEPRADGSRRTTRYD---------IDMTKCIYCGFCQEACP 202
Cdd:pfam13484   1 CGSCGKCIDACPTGAIVgpeGVLDARRCISYLTIEKKglipdelrcLLGNRCYGCDICQDVCP 63
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 184-206 8.92e-06

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 41.46  E-value: 8.92e-06
                          10        20
                  ....*....|....*....|...
gi 1338807362 184 YDIDMTKCIYCGFCQEACPVDAI 206
Cdd:pfam00037   1 VVIDEEKCIGCGACVEVCPVGAI 23
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 158-206 9.61e-06

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 44.94  E-value: 9.61e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1338807362 158 CEAICPAQAITIeaepRADGSRRttrydIDMTKCIYCGFCQEACPVDAI 206
Cdd:COG0437    68 CVKVCPTGATYK----REDGIVL-----VDYDKCIGCRYCVAACPYGAP 107
NapF COG1145
Ferredoxin [Energy production and conversion];
148-211 1.28e-05

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 45.10  E-value: 1.28e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1338807362 148 GEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPN 211
Cdd:COG1145   141 EAGLAILGAAAPVDALAISGGKKIEEELKIAIKKAKAVIDAEKCIGCGLCVKVCPTGAIRLKDG 204
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
149-206 1.60e-05

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 42.63  E-value: 1.60e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 149 EERCIACKLCEAICPAQAITIeaepRADGSrrttrYDIDMTKCIYCGFCQEACPVDAI 206
Cdd:PRK09623   50 ESKCVKCYICWKFCPEPAIYI----KEDGY-----VAIDYDYCKGCGICANECPTKAI 98
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 152-206 1.87e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 43.03  E-value: 1.87e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1338807362 152 CIACKL--CEAICPAQAItieaEPRADGSRRTTRydidmTKCIYCGFCQEACPVDAI 206
Cdd:cd16370    53 CRACEDppCAEACPTGAL----EPRKGGGVVLDK-----EKCIGCGNCVKACIVGAI 100
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 149-206 2.05e-05

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 45.12  E-value: 2.05e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYdidmtKCIYCG------FCQEACPVDAI 206
Cdd:PRK12769   84 QQKCIGCKSCVVACPFGTMQIVLTPVAAGKVKATAH-----KCDLCAgrengpACVENCPADAL 142
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 151-206 2.17e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 43.40  E-value: 2.17e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1338807362 151 RCIACKLCEAICPAQAITIeaEPRADGSR--RTTRYDIDMTKCIYCG-FCQEACPVDAI 206
Cdd:cd16373    15 LCIRCGLCVEACPTGVIQP--AGLEDGLEggRTPYLDPREGPCDLCCdACVEVCPTGAL 71
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
150-212 3.28e-05

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 42.72  E-value: 3.28e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 150 ERCIACKLCEAICPAQAITIEAE---PRADGSRRTTRYDIDMtkCIYC--GFCQEACPVDAIVEGPNF 212
Cdd:COG1142    10 EKCIGCRTCEAACAVAHEGEEGEpflPRIRVVRKAGVSAPVQ--CRHCedAPCAEVCPVGAITRDDGA 75
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 180-211 3.53e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 41.18  E-value: 3.53e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1338807362 180 RTT--RYDIDMTKCIYCGFCQEACPVDAIVEGPN 211
Cdd:COG4231    11 RTTamRYVIDEDKCTGCGACVKVCPADAIEEGDG 44
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 149-206 4.41e-05

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 43.44  E-value: 4.41e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAE--PRadgsrrttrydIDMTKCIYCGFCQEACPVDAI 206
Cdd:COG2878   136 EYGCIGCGDCIKACPFDAIVGAAKgmHT-----------VDEDKCTGCGLCVEACPVDCI 184
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 149-206 4.80e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 41.79  E-value: 4.80e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEpradgsrrtTRYdidMTKCIYCG---FCQEACPVDAI 206
Cdd:cd10550    79 EDKCIGCGMCVEACPFGAIRVDPE---------TGK---AIKCDLCGgdpACVKVCPTGAL 127
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 186-221 5.65e-05

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 40.08  E-value: 5.65e-05
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1338807362 186 IDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEE 221
Cdd:COG1146     5 IDTDKCIGCGACVEVCPVDVLELDEEGKKALVINPE 40
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 149-207 5.85e-05

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 42.48  E-value: 5.85e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1338807362 149 EERCIACKLCEAICPAQAITieAEPRAdgsrrttRYDIDMTKCIYCGFCQEACPVDAIV 207
Cdd:TIGR01944 112 EDNCIGCTKCIQACPVDAIV--GAAKA-------MHTVIADECTGCDLCVEPCPTDCIE 161
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 149-177 7.23e-05

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 40.08  E-value: 7.23e-05
                          10        20
                  ....*....|....*....|....*....
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRADG 177
Cdd:COG1146    39 PEECIGCGACELVCPVGAITVEDDEPEEQ 67
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 158-206 7.32e-05

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 42.13  E-value: 7.32e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1338807362 158 CEAICPAQAITIeaepRADGsrrttRYDIDMTKCIYCGFCQEACPVDAI 206
Cdd:cd10551    61 CVKVCPTGATYK----REDG-----IVLVDYDKCIGCRYCMAACPYGAR 100
PRK09898 PRK09898
ferredoxin-like protein;
149-206 9.02e-05

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 42.13  E-value: 9.02e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRADgsrrttrydidmTKCIYCGFCQEACPVDAI 206
Cdd:PRK09898  153 HKRCIGCSACTTACPWMMATVNTESKKS------------SKCVLCGECANACPTGAL 198
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 149-210 9.15e-05

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 41.22  E-value: 9.15e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 149 EERCIACKLCEAICPaQAITIEAEPRADGSRRTTRYDIDM----TKCIYCGF--CQEACPVDAIVEGP 210
Cdd:cd04410     5 LDRCIGCGTCEVACK-QEHGLRPGPDWSRIKVIEGGGLERaflpVSCMHCEDppCVKACPTGAIYKDE 71
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 158-207 1.02e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 41.01  E-value: 1.02e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1338807362 158 CEAICPAQAITIeaepRADGsrrTTRYDIDmtKCIYCGFCQEACPVDAIV 207
Cdd:cd16371    62 CVKVCPTGAITK----REDG---IVVVDQD--KCIGCGYCVWACPYGAPQ 102
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 186-207 1.63e-04

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 38.94  E-value: 1.63e-04
                          10        20
                  ....*....|....*....|..
gi 1338807362 186 IDMTKCIYCGFCQEACPVDAIV 207
Cdd:COG1149     8 IDEEKCIGCGLCVEVCPEGAIK 29
porD PRK09624
pyruvate ferredoxin oxidoreductase subunit delta; Reviewed
 149-207 1.63e-04

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 170017 [Multi-domain]  Cd Length: 105  Bit Score: 40.01  E-value: 1.63e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEpradgsrrttRYDI-DMTKCIYCGFCQEACPVDAIV 207
Cdd:PRK09624   50 RDKCVRCYLCYIYCPEPAIYLDEE----------GYPVfDYDYCKGCGICANECPTKAIE 99
PRK08318 PRK08318
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;
149-208 1.80e-04

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;


Pssm-ID: 236237 [Multi-domain]  Cd Length: 420  Bit Score: 42.24  E-value: 1.80e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338807362 149 EERCIACKLCEAIC---PAQAITIEAepraDGSRRttrYDIDMTKCIYCGFCQEACPVDAIVE 208
Cdd:PRK08318  341 QDKCIGCGRCYIACedtSHQAIEWDE----DGTRT---PEVIEEECVGCNLCAHVCPVEGCIT 396
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 143-206 2.14e-04

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 40.30  E-value: 2.14e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338807362 143 RRYPSGEE-----RCIACKLCEAICPAQAITIeaepradGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 206
Cdd:cd10564     1 RPPWAVDEalfldLCTRCGDCVEACPEGIIVR-------GDGGFPELDFSRGECTFCGACAEACPEGAL 62
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 177-217 2.42e-04

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 38.88  E-value: 2.42e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1338807362 177 GSRRTTRYDIDMTKCIYCGFCQEACPVDAI--VEGPNFEFSTE 217
Cdd:COG1144    18 GGWRVERPVVDEDKCIGCGLCWIVCPDGAIrvDDGKYYGIDYD 60
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 141-206 2.58e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 39.95  E-value: 2.58e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338807362 141 ALRRYPSG-----EERCIACKLCEAICPAQAITIEAEpradgsrrtTRYDIdmtKCIYCGFCQEACPVDAI 206
Cdd:cd16370    69 ALEPRKGGgvvldKEKCIGCGNCVKACIVGAIFWDEE---------TNKPI---ICIHCGYCARYCPHDVL 127
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 186-212 3.38e-04

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 40.17  E-value: 3.38e-04
                          10        20
                  ....*....|....*....|....*..
gi 1338807362 186 IDMTKCIYCGFCQEACPVDAIVEGPNF 212
Cdd:TIGR01944 110 IDEDNCIGCTKCIQACPVDAIVGAAKA 136
oorD PRK09626
2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed
 149-220 3.75e-04

2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed


Pssm-ID: 236597 [Multi-domain]  Cd Length: 103  Bit Score: 38.93  E-value: 3.75e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRAD-GSRRTTRYDidmTKCIYCGFCQEACPVDAI--VEGPNFEFSTETHE 220
Cdd:PRK09626   15 ESRCKACDICVSVCPAGVLAMRIDPHAVlGKMIKVVHP---ESCIGCRECELHCPDFAIyvADRKEFKFAKLSKE 86
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 152-207 4.74e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 38.86  E-value: 4.74e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 152 CIACKLCEAICPAQAITieaepradgsrRTTR--YDIDMTKCIYCGFCQEACPVDAIV 207
Cdd:cd16372    49 CNQCGECIDVCPTGAIT-----------RDANgvVMINKKLCVGCLMCVGFCPEGAMF 95
PRK06259 PRK06259
succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Provisional
 130-202 4.75e-04

succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Provisional


Pssm-ID: 235756 [Multi-domain]  Cd Length: 486  Bit Score: 40.76  E-value: 4.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 130 GPLSPRFRGEHALRRYPSGEER------CIACKLCEAICPAQAIT-------------IEAEPRADGSRRTTRYDIDMTK 190
Cdd:PRK06259  107 KSLRNYLQRKNEKITYPEDIEDikklrgCIECLSCVSTCPARKVSdypgptfmrqlarFAFDPRDEGDREKEAFDEGLYN 186

                          90
                  ....*....|..
gi 1338807362 191 CIYCGFCQEACP 202
Cdd:PRK06259  187 CTTCGKCVEVCP 198
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 151-206 4.84e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 39.18  E-value: 4.84e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 151 RCIACK--LCEAICPAQAITIEAepraDGSRRttrydIDMTKCIYCGFCQEACPVDAI 206
Cdd:cd16374    42 RCRHCEdaPCMEVCPTGAIYRDE----DGAVL-----VDPDKCIGCGMCAMACPFGVP 90
PRK12576 PRK12576
succinate dehydrogenase/fumarate reductase iron-sulfur subunit;
102-204 5.26e-04

succinate dehydrogenase/fumarate reductase iron-sulfur subunit;


Pssm-ID: 237143 [Multi-domain]  Cd Length: 279  Bit Score: 40.50  E-value: 5.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338807362 102 WTELFRGLGMTMSYLFRepatiNYPFEKGPLSPRFRGEHALRRYPSGEerCIACKLCEAICPAQAITIE----------- 170
Cdd:PRK12576  111 FDEFYERMFKVKPRLYR-----AKEVLEGKAEHRLKPEDQKELWKFAQ--CIWCGLCVSACPVVAIDPEflgpaahakgy 183

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1338807362 171 ---AEPRADGSRRTTRYDIDMT-KCIYCGFCQEACPVD 204
Cdd:PRK12576  184 rflADPRDTITEERMKILIDSSwRCTYCYSCSNVCPRD 221
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 149-211 5.43e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 38.86  E-value: 5.43e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1338807362 149 EERCIACKLCEAICpaqAITIEAEPRADGSR---RTTRYDIDMTKCIYCGFCQEACPVDAIVEGPN 211
Cdd:cd16372     7 PEKCIGCLQCEEAC---SKTFFKEEDREKSCiriTETEGGYAINVCNQCGECIDVCPTGAITRDAN 69
RDH TIGR02486
reductive dehalogenase; This model represents a family of corrin and 8-iron Fe-S ...
 152-202 5.49e-04

reductive dehalogenase; This model represents a family of corrin and 8-iron Fe-S cluster-containing reductive dehalogenases found primarily in halorespiring microorganisms such as dehalococcoides ethenogenes which contains as many as 17 enzymes of this type with varying substrate ranges. One example of a characterized species is the tetrachloroethene reductive dehalogenase (1.97.1.8) which also acts on trichloroethene converting it to dichloroethene.


Pssm-ID: 274158  Cd Length: 314  Bit Score: 40.50  E-value: 5.49e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338807362 152 CIACKLCEAICPAQAITIEAEPRADGSRRTTRYD----------IDMTKCI----------YCGFCQEACP 202
Cdd:TIGR02486 207 CETCGKCADECPSGAISKGGEPTWDPEDSNGDPPgennpglkwqYDGWRCLlfrcynegggGCGVCQAVCP 277
PRK09898 PRK09898
ferredoxin-like protein;
150-202 5.66e-04

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 39.82  E-value: 5.66e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1338807362 150 ERCIACK--LCEAICPAQAITIEAEPRAdgsrrttrYDIDMTKCIYCGFCQEACP 202
Cdd:PRK09898  121 DTCRQCKepQCMNVCPIGAITWQQKEGC--------ITVDHKRCIGCSACTTACP 167
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 150-206 7.57e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 38.33  E-value: 7.57e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338807362 150 ERCIACKLCEAIC---------PAQA-ITIEAEPRADgsrrttrYDIDMTkCIYCG--FCQEACPVDAI 206
Cdd:cd10550     6 EKCTGCRTCELACslkhegvfnPSLSrIRVVRFEPEG-------LDVPVV-CRQCEdaPCVEACPVGAI 66
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 141-206 1.06e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 38.09  E-value: 1.06e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338807362 141 ALRRYPSG-----EERCIACKLCEAICPAQAItIEAEPRadgsrrttrydIDMTKCIYCGFCQEACPVDAI 206
Cdd:cd16372    63 AITRDANGvvminKKLCVGCLMCVGFCPEGAM-FKHEDY-----------PEPFKCIACGICVKACPTGAL 121
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 150-217 1.29e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 38.02  E-value: 1.29e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338807362 150 ERCIACKLCEAICPAQAITIEAEPRAdgsrrttrydidMTKCIYCG---------FCQEACPVDAIVEGPNFEFSTE 217
Cdd:cd16374    73 DKCIGCGMCAMACPFGVPRFDPSLKV------------AVKCDLCIdrrregklpACVEACPTGALKFGDIEELLKE 137
PRK06991 PRK06991
electron transport complex subunit RsxB;
186-210 1.42e-03

electron transport complex subunit RsxB;


Pssm-ID: 235903 [Multi-domain]  Cd Length: 270  Bit Score: 39.01  E-value: 1.42e-03
                          10        20
                  ....*....|....*....|....*
gi 1338807362 186 IDMTKCIYCGFCQEACPVDAIVEGP 210
Cdd:PRK06991   82 IDEQLCIGCTLCMQACPVDAIVGAP 106
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 149-168 1.44e-03

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 35.30  E-value: 1.44e-03
                          10        20
                  ....*....|....*....|
gi 1338807362 149 EERCIACKLCEAICPAQAIT 168
Cdd:pfam00037   5 EEKCIGCGACVEVCPVGAIT 24
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 185-211 1.50e-03

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 37.76  E-value: 1.50e-03
                          10        20
                  ....*....|....*....|....*..
gi 1338807362 185 DIDMTKCIYCGFCQEACPVDAIVEGPN 211
Cdd:cd10549     2 KYDPEKCIGCGICVKACPTDAIELGPN 28
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 181-206 1.85e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 36.18  E-value: 1.85e-03
                          10        20
                  ....*....|....*....|....*.
gi 1338807362 181 TTRYDIDMTKCIYCGFCQEACPVDAI 206
Cdd:COG2221     7 TWPPKIDEEKCIGCGLCVAVCPTGAI 32
NapF COG1145
Ferredoxin [Energy production and conversion];
149-173 1.86e-03

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 38.55  E-value: 1.86e-03
                          10        20
                  ....*....|....*....|....*
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEP 173
Cdd:COG1145   212 PDKCIGCGACVKVCPVGAISLEPKE 236
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 149-175 2.05e-03

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 36.17  E-value: 2.05e-03
                          10        20
                  ....*....|....*....|....*..
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRA 175
Cdd:COG4231    50 PDLCIGCGSCVQVCPVDAIKLEKRVPE 76
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 149-213 2.35e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 38.44  E-value: 2.35e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPrADGSRRTTRYDIDMTKCIYC-GFCQEACPVDAIVEGPNFE 213
Cdd:COG2878   166 EDKCTGCGLCVEACPVDCIEMVPVS-PTVVVSSWDKGKAVRKVVGCiGLCCKKCCPAAAITVNNLA 230
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
149-184 2.39e-03

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 35.86  E-value: 2.39e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1338807362 149 EERCIACKLCEAICPAQAITIEAEPRADGSRRTTRY 184
Cdd:COG2768    39 PEKCIGCGACIEVCPVGAIKIEWEEDEEFQEKMAEY 74
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 149-170 2.41e-03

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 36.99  E-value: 2.41e-03
                          10        20
                  ....*....|....*....|..
gi 1338807362 149 EERCIACKLCEAICPAQAITIE 170
Cdd:cd10549   107 KEKCIGCGICAEVCPVNAIKLV 128
PRK05113 PRK05113
electron transport complex protein RnfB; Provisional
 186-207 2.59e-03

electron transport complex protein RnfB; Provisional


Pssm-ID: 235347 [Multi-domain]  Cd Length: 191  Bit Score: 37.62  E-value: 2.59e-03
                          10        20
                  ....*....|....*....|..
gi 1338807362 186 IDMTKCIYCGFCQEACPVDAIV 207
Cdd:PRK05113  111 IDEDNCIGCTKCIQACPVDAIV 132
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 158-206 2.86e-03

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 37.28  E-value: 2.86e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1338807362 158 CEAICPAQAITIEAepraDGSrrttrYDIDMTKCIYCGFCQEACPVDAI 206
Cdd:cd10562    78 CVKVCPTGALYKTE----NGA-----VVVDEDKCIGCGYCVAACPFDVP 117
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 149-218 3.94e-03

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 37.56  E-value: 3.94e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338807362 149 EERCIACKLCEAICPAQAITIEaepraDGSRRTTrydiDMTKCIYCGFCQEACPVDAIVEG--PN-FEFSTET 218
Cdd:PRK00783  168 SEDCDECEKCVEACPRGVLELK-----EGKLVVT----DLLNCSLCKLCERACPGKAIRVSddENkFIFTVES 231
CooF_like cd10563
CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the ...
 141-207 4.82e-03

CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the iron-sulfur subunit of carbon monoxide dehydrogenase (CODH), found in anaerobic bacteria and archaea. Carbon monoxide dehydrogenase is a key enzyme for carbon monoxide (CO) metabolism, where CooF is the proposed mediator of electron transfer between CODH and the CO-induced hydrogenase, catalyzing the reaction that uses CO as a single carbon and energy source, and producing only H2 and CO2. The ion-sulfur subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons in the protein complex during reaction.


Pssm-ID: 319885 [Multi-domain]  Cd Length: 140  Bit Score: 36.46  E-value: 4.82e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 141 ALRRYP-SG-----EERCIACKLCEAICPAQAITIEAEPRAdgsrrttrydidMTKCIYCGF-----CQEACPVDAIV 207
Cdd:cd10563    73 AMHKDPeTGivihdEEKCVGCWMCVMVCPYGAIRPDKERKV------------ALKCDLCPDretpaCVEACPTGALV 138
Fer4_8 pfam13183
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 151-204 5.16e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 433017 [Multi-domain]  Cd Length: 64  Bit Score: 34.59  E-value: 5.16e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338807362 151 RCIACKLCEAICPA---------QAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVD 204
Cdd:pfam13183   1 RCIRCGACLAACPVylvtggrfpGDPRGGAAALLGRLEALEGLAEGLWLCTLCGACTEVCPVG 63
porD PRK09625
pyruvate flavodoxin oxidoreductase subunit delta; Reviewed
 150-202 5.41e-03

pyruvate flavodoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 236596 [Multi-domain]  Cd Length: 133  Bit Score: 36.26  E-value: 5.41e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1338807362 150 ERCIACKLCEAICPAQAITieaepradgSRRTTRYDIDMTKCIYCGFCQEACP 202
Cdd:PRK09625   59 EICINCFNCWVYCPDAAIL---------SRDKKLKGVDYSHCKGCGVCVEVCP 102
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 153-206 6.55e-03

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 36.08  E-value: 6.55e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1338807362 153 IACKLCE-----AICPAQAITieaepRADGSRRttrydIDMTKCIYCGFCQEACPVDAI 206
Cdd:cd10554    54 VQCRQCEdapcaNVCPVGAIS-----QEDGVVQ-----VDEERCIGCKLCVLACPFGAI 102
QueG COG1600
Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and ...
 149-202 8.02e-03

Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and biogenesis]; Epoxyqueuosine reductase QueG (queuosine biosynthesis) is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441208 [Multi-domain]  Cd Length: 345  Bit Score: 37.11  E-value: 8.02e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338807362 149 EERCIACKLCEAICPAQAITieaEPradgsrrttrYDIDMTKCI-Y-----------------------CGFCQEACP 202
Cdd:COG1600   183 EDHCGSCTRCLDACPTGAIV---AP----------YVLDARRCIsYltielkgpipeelrpkmgnriygCDDCQDVCP 247
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 149-210 8.96e-03

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 35.74  E-value: 8.96e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338807362 149 EERCIACKLCEAICPAQAItieaepradgsrRTTRYDIDMTKCIYC------GF---CQEACPVDAIVEGP 210
Cdd:cd10562    99 EDKCIGCGYCVAACPFDVP------------RYDETTNKITKCTLCfdrienGMqpaCVKTCPTGALTFGD 157
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 191-211 9.76e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 36.51  E-value: 9.76e-03
                          10        20
                  ....*....|....*....|.
gi 1338807362 191 CIYCGFCQEACPVDAIVEGPN 211
Cdd:COG2878   139 CIGCGDCIKACPFDAIVGAAK 159
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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