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Conserved domains on  [gi|1333175532|ref|XP_023518819|]
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trafficking protein particle complex subunit 12 [Cucurbita pepo subsp. pepo]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
218-339 7.19e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 46.92  E-value: 7.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 218 LSRDFSDPALISKLGYIQMHVGDIEGAKRSFNKiedmvkegksSVSLSEVEIKNLVNRnkALVFLVGKDYLSAVREYEEC 297
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEK----------ALELDPDDAEALYNL--GLAYLRLGRYEEALADYEQA 68

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1333175532 298 IERDHTDVVAINNKALCLMYLRDLADSIKVLENALERVPTVA 339
Cdd:COG0457    69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDA 110
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
218-339 7.19e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 46.92  E-value: 7.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 218 LSRDFSDPALISKLGYIQMHVGDIEGAKRSFNKiedmvkegksSVSLSEVEIKNLVNRnkALVFLVGKDYLSAVREYEEC 297
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEK----------ALELDPDDAEALYNL--GLAYLRLGRYEEALADYEQA 68

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1333175532 298 IERDHTDVVAINNKALCLMYLRDLADSIKVLENALERVPTVA 339
Cdd:COG0457    69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDA 110
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
218-339 7.19e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 46.92  E-value: 7.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 218 LSRDFSDPALISKLGYIQMHVGDIEGAKRSFNKiedmvkegksSVSLSEVEIKNLVNRnkALVFLVGKDYLSAVREYEEC 297
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEK----------ALELDPDDAEALYNL--GLAYLRLGRYEEALADYEQA 68

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1333175532 298 IERDHTDVVAINNKALCLMYLRDLADSIKVLENALERVPTVA 339
Cdd:COG0457    69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDA 110
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 211-336 2.22e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.03  E-value: 2.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 211 LSLIDNLLSRDFSDPALISKLGYIQMHVGDIEGAKRSFNKIEDMVKEgkssvslsEVEIKNlvnrNKALVFLVGKDYLSA 290
Cdd:COG4783    24 EALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD--------EPEARL----NLGLALLKAGDYDEA 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1333175532 291 VREYEECIERDHTDVVAINNKALCLMYLRDLADSIKVLENALERVP 336
Cdd:COG4783    92 LALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 160-340 3.04e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.11  E-value: 3.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 160 LYEL-LDFVQSKVKDKQEKNLDVSVDLwKKREVFVINCIMGHHLSNKEFGVCLSLIDNLLSRDFSDPALISKLGYIQMHV 238
Cdd:COG2956    79 LLELaQDYLKAGLLDRAEELLEKLLEL-DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 239 GDIEGAKRSFNKIedmVKEGKSSVSlseveiknlVNRNKALVFLVGKDYLSAVREYEECIERDHTDVVAINNKALCLMYL 318
Cdd:COG2956   158 GDYDEAIEALEKA---LKLDPDCAR---------ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225

                         170       180
                  ....*....|....*....|..
gi 1333175532 319 RDLADSIKVLENALERVPTVAL 340
Cdd:COG2956   226 GDPEEALELLRKALELDPSDDL 247
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
218-339 3.46e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.00  E-value: 3.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 218 LSRDFSDPALISKLGYIQMHVGDIEGAKRSFNKiedmvkegksSVSLSEVEIKNLVNRnkALVFLVGKDYLSAVREYEEC 297
Cdd:COG0457    35 LELDPDDAEALYNLGLAYLRLGRYEEALADYEQ----------ALELDPDDAEALNNL--GLALQALGRYEEALEDYDKA 102

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1333175532 298 IERDHTDVVAINNKALCLMYLRDLADSIKVLENALERVPTVA 339
Cdd:COG0457   103 LELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDA 144
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 226-336 4.41e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 4.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 226 ALISKLGYIQMHVGDIEGAKRSFNKiedmvkegksSVSLSEVEIKNLVNRnkALVFLVGKDYLSAVREYEECIERDHTDV 305
Cdd:COG5010    55 AIESPSDNLYNKLGDFEESLALLEQ----------ALQLDPNNPELYYNL--ALLYSRSGDKDEAKEYYEKALALSPDNP 122

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1333175532 306 VAINNKALCLMYLRDLADSIKVLENALERVP 336
Cdd:COG5010   123 NAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 285-355 1.21e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.25  E-value: 1.21e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1333175532 285 KDYLSAVREYEECIERDHTDVVAINNKALCLMYLRDLADSIKVLENALERVPTvalNETVIVNLCSMYELA 355
Cdd:COG5010    68 GDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---NPNAYSNLAALLLSL 135
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 201-339 1.70e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.79  E-value: 1.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 201 HLSNKEFGVCLSLIDNLLSRDFSDPALISKLGYIQMHVGDIEGAKRSFNKIedmvkegkssvsLSEVEIKNLVNRNKALV 280
Cdd:COG2956    18 YLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKL------------LERDPDRAEALLELAQD 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1333175532 281 FLVGKDYLSAVREYEECIERDHTDVVAINNKALCLMYLRDLADSIKVLENALERVPTVA 339
Cdd:COG2956    86 YLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENA 144
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 230-336 4.33e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 4.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 230 KLGYIQMHVGDIEGAKRSFNKIedmVKEGKSSVSlseveiknlVNRNKALVFLVGKDYLSAVREYEECIERDHTDVVAIN 309
Cdd:COG4783     9 ALAQALLLAGDYDEAEALLEKA---LELDPDNPE---------AFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARL 76

                          90       100
                  ....*....|....*....|....*..
gi 1333175532 310 NKALCLMYLRDLADSIKVLENALERVP 336
Cdd:COG4783    77 NLGLALLKAGDYDEALALLEKALKLDP 103
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
276-337 8.40e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.28  E-value: 8.40e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1333175532 276 NKALVFLVGKDYLSAVREYEECIERDHTDVVAINNKALCLMYLRDLADSIKVLENALERVPT 337
Cdd:COG4785   112 NRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPN 173
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 216-336 1.28e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.10  E-value: 1.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 216 NLLSRDFSDPALISKLGYIQMHVGDIEGAKRSFNKIEDMVKEGKSsvslseveiknlVNRNKALVFLVGKDYLSAVREYE 295
Cdd:COG2956    67 KLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAE------------ALRLLAEIYEQEGDWEKAIEVLE 134

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1333175532 296 ECIERDHTDVVAINNKALCLMYLRDLADSIKVLENALERVP 336
Cdd:COG2956   135 RLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDP 175
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
211-334 1.42e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.99  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 211 LSLIDNLLSRDFSDPALISKLGYIQMHVGDIEGAKRSFNKIedmvkegkssvslseVEIKN---LVNRNKALVFLVGKDY 287
Cdd:COG0457    62 LADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKA---------------LELDPddaEALYNLGLALLELGRY 126

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1333175532 288 LSAVREYEECIERDHTDVVAINNKALCLMYLRDLADSIKVLENALER 334
Cdd:COG0457   127 DEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAA 173
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 275-336 1.46e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.63  E-value: 1.46e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1333175532 275 RNKALVFLVGKDYLSAVREYEECIERDHTDVVAINNKALCLMYLRDLADSIKVLENALERVP 336
Cdd:COG4783     8 YALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDP 69
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
285-339 1.79e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.46  E-value: 1.79e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1333175532 285 KDYLSAVREYEECIERDHTDVVAINNKALCLMYLRDLADSIKvLENALERVPTVA 339
Cdd:COG3063     6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNA 59
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
234-336 2.89e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.69  E-value: 2.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333175532 234 IQMHVGDIEGAKRSFNKiedmvkegksSVSLSEVEIknLVNRNKALVFLVGKDYLSAvREYEECIERDHTDVVAINNKAL 313
Cdd:COG3063     1 LYLKLGDLEEAEEYYEK----------ALELDPDNA--DALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAE 67

                          90       100
                  ....*....|....*....|...
gi 1333175532 314 CLMYLRDLADSIKVLENALERVP 336
Cdd:COG3063    68 LLLELGDYDEALAYLERALELDP 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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