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Conserved domains on  [gi|1281044098|ref|XP_023006773|]
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probable purine permease 11 isoform X1 [Cucurbita maxima]

Protein Classification

purine permease( domain architecture ID 12180965)

purine permease is a proton-coupled transporter that mediates the uptake of nucleosides, nucleotides, and their derivatives, such as adenine and cytosine, as well as purine derivatives (hypoxanthine), phytohormones (zeatin and kinetin), and alkaloids (caffeine and nicotine)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PUNUT pfam16913
Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal ...
 32-349 3.80e-135

Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal purine transporters. Most members are 10-pass transmembrane proteins, and they belong to the drug/metabolite transporter (dmt) superfamily. The plant vascular system transports nucloebases and their derivatives such as cytokinins and caffeine by a common H+-coupled high-affinity purine transport system; the PUNUT family members carry out this transport.


:

Pssm-ID: 293518 [Multi-domain]  Cd Length: 321  Bit Score: 388.18  E-value: 3.80e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098  32 LVALNIFFLIVGQAAAVLLGRFYYDQGGNSKWMATVVQTAAFPVLFIPLFLFRSAKDTSTSTNP--PSILVLLLIYFSLG 109
Cdd:pfam16913   2 LVIISIFFLLIGQAISTLLGRLYFVNGGKSTWLQTLVQTAGFPLLLLPLLFSFLSKKRNQETTSfsSSFKRLVIIYIVLG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098 110 SVIALDNWLYSTGLLYLSASTYSLVCASQLAFNAVFSYFINSQKFTILISNSVIILSLSSALLAVDDDSERPSGVSKSKY 189
Cdd:pfam16913  82 LLVGADNFLYSYGLLYLPVSTFSLILATQLAFTAIFSYFINKQKFTPFIINSVVLLTISAALLALDSSSDKPSGESKKKY 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098 190 FFGFICALGASALYSLLLSLMQLTFQKVLKRETFTVVLEMQIYTSIVATIVSVVALFASGEWKSLPHEMAGFGKGRVSYV 269
Cdd:pfam16913 162 VIGFWCTIGASALFSLILCLVELAFEKVLKRRTFSMVLEMQIVMSLVATCVCVIGLFASGEFKDLKGEMEEFKKGKSLYV 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098 270 LTLVGTAVAWQTCSVGVVGLIFIVSSLFSNAISTVSLAVTPLAALVIFHDKMNGVKIIALLLAIWGFVTYLYQNYIDESK 349
Cdd:pfam16913 242 LTLVGTAVSWQVYFVGAVGLVFLVSSLFSNVISTVLLPVVPVLAVIAFHDKFSGFKGVALVLAIWGFASYFYGLYKDKKK 321
 
Name Accession Description Interval E-value
PUNUT pfam16913
Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal ...
 32-349 3.80e-135

Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal purine transporters. Most members are 10-pass transmembrane proteins, and they belong to the drug/metabolite transporter (dmt) superfamily. The plant vascular system transports nucloebases and their derivatives such as cytokinins and caffeine by a common H+-coupled high-affinity purine transport system; the PUNUT family members carry out this transport.


Pssm-ID: 293518 [Multi-domain]  Cd Length: 321  Bit Score: 388.18  E-value: 3.80e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098  32 LVALNIFFLIVGQAAAVLLGRFYYDQGGNSKWMATVVQTAAFPVLFIPLFLFRSAKDTSTSTNP--PSILVLLLIYFSLG 109
Cdd:pfam16913   2 LVIISIFFLLIGQAISTLLGRLYFVNGGKSTWLQTLVQTAGFPLLLLPLLFSFLSKKRNQETTSfsSSFKRLVIIYIVLG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098 110 SVIALDNWLYSTGLLYLSASTYSLVCASQLAFNAVFSYFINSQKFTILISNSVIILSLSSALLAVDDDSERPSGVSKSKY 189
Cdd:pfam16913  82 LLVGADNFLYSYGLLYLPVSTFSLILATQLAFTAIFSYFINKQKFTPFIINSVVLLTISAALLALDSSSDKPSGESKKKY 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098 190 FFGFICALGASALYSLLLSLMQLTFQKVLKRETFTVVLEMQIYTSIVATIVSVVALFASGEWKSLPHEMAGFGKGRVSYV 269
Cdd:pfam16913 162 VIGFWCTIGASALFSLILCLVELAFEKVLKRRTFSMVLEMQIVMSLVATCVCVIGLFASGEFKDLKGEMEEFKKGKSLYV 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098 270 LTLVGTAVAWQTCSVGVVGLIFIVSSLFSNAISTVSLAVTPLAALVIFHDKMNGVKIIALLLAIWGFVTYLYQNYIDESK 349
Cdd:pfam16913 242 LTLVGTAVSWQVYFVGAVGLVFLVSSLFSNVISTVLLPVVPVLAVIAFHDKFSGFKGVALVLAIWGFASYFYGLYKDKKK 321
 
Name Accession Description Interval E-value
PUNUT pfam16913
Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal ...
 32-349 3.80e-135

Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal purine transporters. Most members are 10-pass transmembrane proteins, and they belong to the drug/metabolite transporter (dmt) superfamily. The plant vascular system transports nucloebases and their derivatives such as cytokinins and caffeine by a common H+-coupled high-affinity purine transport system; the PUNUT family members carry out this transport.


Pssm-ID: 293518 [Multi-domain]  Cd Length: 321  Bit Score: 388.18  E-value: 3.80e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098  32 LVALNIFFLIVGQAAAVLLGRFYYDQGGNSKWMATVVQTAAFPVLFIPLFLFRSAKDTSTSTNP--PSILVLLLIYFSLG 109
Cdd:pfam16913   2 LVIISIFFLLIGQAISTLLGRLYFVNGGKSTWLQTLVQTAGFPLLLLPLLFSFLSKKRNQETTSfsSSFKRLVIIYIVLG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098 110 SVIALDNWLYSTGLLYLSASTYSLVCASQLAFNAVFSYFINSQKFTILISNSVIILSLSSALLAVDDDSERPSGVSKSKY 189
Cdd:pfam16913  82 LLVGADNFLYSYGLLYLPVSTFSLILATQLAFTAIFSYFINKQKFTPFIINSVVLLTISAALLALDSSSDKPSGESKKKY 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098 190 FFGFICALGASALYSLLLSLMQLTFQKVLKRETFTVVLEMQIYTSIVATIVSVVALFASGEWKSLPHEMAGFGKGRVSYV 269
Cdd:pfam16913 162 VIGFWCTIGASALFSLILCLVELAFEKVLKRRTFSMVLEMQIVMSLVATCVCVIGLFASGEFKDLKGEMEEFKKGKSLYV 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281044098 270 LTLVGTAVAWQTCSVGVVGLIFIVSSLFSNAISTVSLAVTPLAALVIFHDKMNGVKIIALLLAIWGFVTYLYQNYIDESK 349
Cdd:pfam16913 242 LTLVGTAVSWQVYFVGAVGLVFLVSSLFSNVISTVLLPVVPVLAVIAFHDKFSGFKGVALVLAIWGFASYFYGLYKDKKK 321
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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