NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1281006283|ref|XP_022987086|]
View 

protein LURP-one-related 6 [Cucurbita maxima]

Protein Classification

LURP-one-related/scramblase family protein( domain architecture ID 1453)

LURP-one-related/scramblase family protein similar to Arabidopsis thaliana protein LURP16, which might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors

PubMed:  19010806

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
LOR super family cl02043
LURP-one-related; The structure of this family has been solved. It comprises a 12-stranded ...
2-190 7.81e-34

LURP-one-related; The structure of this family has been solved. It comprises a 12-stranded beta barrel with a central C-terminal alpha helix. This helix is thought to be a transmembrane helix. It is structurally similar to the C-terminal domain of the Tubby protein. In plants it plays a role in defense against pathogens.


The actual alignment was detected with superfamily member pfam04525:

Pssm-ID: 470445  Cd Length: 186  Bit Score: 119.09  E-value: 7.81e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281006283   2 IPLVSKFYCSSSEVVFVVRTRPHVINGGGFVVTDCNQKVVFSVDGCgILGKEEELVVRDEKRDALLLLRGKGgifeaLSF 81
Cdd:pfam04525   1 GVVVSSEYLSPEPEDLTVWRKSLVFNGDGFTVYDSNGNLVFRVDGY-AFGLSDERVLMDSSGNPLLTIRRKK-----LSL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281006283  82 HKIWKAYKYDFQGSKKLVFSLRRPKSCLPVKNDVGIRITTKPKVSRKD--WDFEVSGYFPDRRCSIIDSQGNAVAQI-GT 158
Cdd:pfam04525  75 HDRWEVYRGESTEGKDPLFTVKRSSIVQLKTSSSVFSKRNSNVIVDDEstCDFDIKGSFLDRSCKIYDESGKIIAEVkRK 154
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1281006283 159 IKKTGEQLSKDIYFVSIKPGVDQAFIVGVVAI 190
Cdd:pfam04525 155 QTSRGVLLGKDVFTLVVKPEVDYAFIMALVVV 186
 
Name Accession Description Interval E-value
LOR pfam04525
LURP-one-related; The structure of this family has been solved. It comprises a 12-stranded ...
2-190 7.81e-34

LURP-one-related; The structure of this family has been solved. It comprises a 12-stranded beta barrel with a central C-terminal alpha helix. This helix is thought to be a transmembrane helix. It is structurally similar to the C-terminal domain of the Tubby protein. In plants it plays a role in defense against pathogens.


Pssm-ID: 398294  Cd Length: 186  Bit Score: 119.09  E-value: 7.81e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281006283   2 IPLVSKFYCSSSEVVFVVRTRPHVINGGGFVVTDCNQKVVFSVDGCgILGKEEELVVRDEKRDALLLLRGKGgifeaLSF 81
Cdd:pfam04525   1 GVVVSSEYLSPEPEDLTVWRKSLVFNGDGFTVYDSNGNLVFRVDGY-AFGLSDERVLMDSSGNPLLTIRRKK-----LSL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281006283  82 HKIWKAYKYDFQGSKKLVFSLRRPKSCLPVKNDVGIRITTKPKVSRKD--WDFEVSGYFPDRRCSIIDSQGNAVAQI-GT 158
Cdd:pfam04525  75 HDRWEVYRGESTEGKDPLFTVKRSSIVQLKTSSSVFSKRNSNVIVDDEstCDFDIKGSFLDRSCKIYDESGKIIAEVkRK 154
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1281006283 159 IKKTGEQLSKDIYFVSIKPGVDQAFIVGVVAI 190
Cdd:pfam04525 155 QTSRGVLLGKDVFTLVVKPEVDYAFIMALVVV 186
YxjI COG4894
Putative phospholipid scramblase YxjI, Tubby2 superfamily [Lipid transport and metabolism];
28-198 4.35e-05

Putative phospholipid scramblase YxjI, Tubby2 superfamily [Lipid transport and metabolism];


Pssm-ID: 443922  Cd Length: 163  Bit Score: 42.13  E-value: 4.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281006283  28 GGGFVVTDCNQKVVFSVDGcGILGKEEELVVRDEKRDALLLLRGKggifeALSFHKiwkayKYDFQGSKKLVFSLRRPKS 107
Cdd:COG4894    14 GDDFTIYDENGQPVYLVKG-KFFSLGDTLSIYDADGNELATIKQK-----LFSLLP-----TFEIYDDGEPVATIKKKFT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281006283 108 CLpvkndvgiriTTKPKVSRKDWDFEVSGYFPDRRCSIIDsQGNAVAQIgtikkTGEQLS-KDIYFVSIKPGVDQAFIVG 186
Cdd:COG4894    83 FF----------KDRFTIEADGLDLEIEGDFWDHDFEITR-GGKVVASV-----SKKWFSwRDTYELDIDDEEDRPLVIA 146
                         170
                  ....*....|..
gi 1281006283 187 VVAILDNIYGES 198
Cdd:COG4894   147 LAIAIDAVLHKE 158
 
Name Accession Description Interval E-value
LOR pfam04525
LURP-one-related; The structure of this family has been solved. It comprises a 12-stranded ...
2-190 7.81e-34

LURP-one-related; The structure of this family has been solved. It comprises a 12-stranded beta barrel with a central C-terminal alpha helix. This helix is thought to be a transmembrane helix. It is structurally similar to the C-terminal domain of the Tubby protein. In plants it plays a role in defense against pathogens.


Pssm-ID: 398294  Cd Length: 186  Bit Score: 119.09  E-value: 7.81e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281006283   2 IPLVSKFYCSSSEVVFVVRTRPHVINGGGFVVTDCNQKVVFSVDGCgILGKEEELVVRDEKRDALLLLRGKGgifeaLSF 81
Cdd:pfam04525   1 GVVVSSEYLSPEPEDLTVWRKSLVFNGDGFTVYDSNGNLVFRVDGY-AFGLSDERVLMDSSGNPLLTIRRKK-----LSL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281006283  82 HKIWKAYKYDFQGSKKLVFSLRRPKSCLPVKNDVGIRITTKPKVSRKD--WDFEVSGYFPDRRCSIIDSQGNAVAQI-GT 158
Cdd:pfam04525  75 HDRWEVYRGESTEGKDPLFTVKRSSIVQLKTSSSVFSKRNSNVIVDDEstCDFDIKGSFLDRSCKIYDESGKIIAEVkRK 154
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1281006283 159 IKKTGEQLSKDIYFVSIKPGVDQAFIVGVVAI 190
Cdd:pfam04525 155 QTSRGVLLGKDVFTLVVKPEVDYAFIMALVVV 186
YxjI COG4894
Putative phospholipid scramblase YxjI, Tubby2 superfamily [Lipid transport and metabolism];
28-198 4.35e-05

Putative phospholipid scramblase YxjI, Tubby2 superfamily [Lipid transport and metabolism];


Pssm-ID: 443922  Cd Length: 163  Bit Score: 42.13  E-value: 4.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281006283  28 GGGFVVTDCNQKVVFSVDGcGILGKEEELVVRDEKRDALLLLRGKggifeALSFHKiwkayKYDFQGSKKLVFSLRRPKS 107
Cdd:COG4894    14 GDDFTIYDENGQPVYLVKG-KFFSLGDTLSIYDADGNELATIKQK-----LFSLLP-----TFEIYDDGEPVATIKKKFT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281006283 108 CLpvkndvgiriTTKPKVSRKDWDFEVSGYFPDRRCSIIDsQGNAVAQIgtikkTGEQLS-KDIYFVSIKPGVDQAFIVG 186
Cdd:COG4894    83 FF----------KDRFTIEADGLDLEIEGDFWDHDFEITR-GGKVVASV-----SKKWFSwRDTYELDIDDEEDRPLVIA 146
                         170
                  ....*....|..
gi 1281006283 187 VVAILDNIYGES 198
Cdd:COG4894   147 LAIAIDAVLHKE 158
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH