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Conserved domains on  [gi|1279789211|ref|XP_022947607|]
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zinc finger CCCH domain-containing protein 3-like [Cucurbita moschata]

Protein Classification

zinc finger CCCH domain-containing protein( domain architecture ID 10457906)

zinc finger CCCH domain-containing protein similar to Homo sapiens proline-rich protein 3 (PRR3)

CATH:  4.10.1000.10
Gene Ontology:  GO:0046872|GO:0003676
PubMed:  12665246|27990022
SCOP:  3001741

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
277-303 8.69e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.96  E-value: 8.69e-08
                          10        20
                  ....*....|....*....|....*..
gi 1279789211 277 PDQPECRYFMNNGTCKYGSDCKFHHPK 303
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
90-115 1.15e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.57  E-value: 1.15e-07
                          10        20
                  ....*....|....*....|....*.
gi 1279789211  90 GQPDCEYFLKTGTCKYGGSCKYHHPR 115
Cdd:pfam00642   2 KTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
47-73 2.12e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.80  E-value: 2.12e-07
                          10        20
                  ....*....|....*....|....*..
gi 1279789211  47 PGEPDCLYYMRTGSCSYGSNCRFNHPV 73
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
139-160 6.46e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 45.26  E-value: 6.46e-07
                          10        20
                  ....*....|....*....|..
gi 1279789211 139 CSYYLRTGSCKFGVSCKFNHPQ 160
Cdd:pfam00642   6 CRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
320-345 8.57e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 42.18  E-value: 8.57e-06
                          10        20
                  ....*....|....*....|....*.
gi 1279789211 320 PGQAVCSYYSMYGLCKYGPSCKFDHP 345
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
 
Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
277-303 8.69e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.96  E-value: 8.69e-08
                          10        20
                  ....*....|....*....|....*..
gi 1279789211 277 PDQPECRYFMNNGTCKYGSDCKFHHPK 303
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
90-115 1.15e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.57  E-value: 1.15e-07
                          10        20
                  ....*....|....*....|....*.
gi 1279789211  90 GQPDCEYFLKTGTCKYGGSCKYHHPR 115
Cdd:pfam00642   2 KTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
47-73 2.12e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.80  E-value: 2.12e-07
                          10        20
                  ....*....|....*....|....*..
gi 1279789211  47 PGEPDCLYYMRTGSCSYGSNCRFNHPV 73
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
139-160 6.46e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 45.26  E-value: 6.46e-07
                          10        20
                  ....*....|....*....|..
gi 1279789211 139 CSYYLRTGSCKFGVSCKFNHPQ 160
Cdd:pfam00642   6 CRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
320-345 8.57e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 42.18  E-value: 8.57e-06
                          10        20
                  ....*....|....*....|....*.
gi 1279789211 320 PGQAVCSYYSMYGLCKYGPSCKFDHP 345
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
ZnF_C3H1 smart00356
zinc finger;
279-303 2.64e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.99  E-value: 2.64e-04
                           10        20
                   ....*....|....*....|....*
gi 1279789211  279 QPECRYFMNnGTCKYGSDCKFHHPK 303
Cdd:smart00356   4 TELCKFFKR-GYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
90-115 4.57e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.22  E-value: 4.57e-04
                           10        20
                   ....*....|....*....|....*.
gi 1279789211   90 GQPDCEYFlKTGTCKYGGSCKYHHPR 115
Cdd:smart00356   3 KTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
319-345 6.69e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.84  E-value: 6.69e-04
                           10        20
                   ....*....|....*....|....*..
gi 1279789211  319 RPGQAVCSYYsMYGLCKYGPSCKFDHP 345
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHP 26
COG5152 COG5152
Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers [General function ...
 91-121 8.45e-04

Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers [General function prediction only];


Pssm-ID: 227481 [Multi-domain]  Cd Length: 259  Bit Score: 40.83  E-value: 8.45e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1279789211  91 QPD-CEYFLKTGTCKYGGSCKYHHPRDRRGAG 121
Cdd:COG5152   140 QPDvCKDYKETGYCGYGDSCKFLHDRSDFKTG 171
ZnF_C3H1 smart00356
zinc finger;
46-72 2.92e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 34.91  E-value: 2.92e-03
                           10        20
                   ....*....|....*....|....*..
gi 1279789211   46 RPGEPDCLYYmRTGSCSYGSNCRFNHP 72
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHP 26
 
Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
277-303 8.69e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.96  E-value: 8.69e-08
                          10        20
                  ....*....|....*....|....*..
gi 1279789211 277 PDQPECRYFMNNGTCKYGSDCKFHHPK 303
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
90-115 1.15e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.57  E-value: 1.15e-07
                          10        20
                  ....*....|....*....|....*.
gi 1279789211  90 GQPDCEYFLKTGTCKYGGSCKYHHPR 115
Cdd:pfam00642   2 KTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
47-73 2.12e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.80  E-value: 2.12e-07
                          10        20
                  ....*....|....*....|....*..
gi 1279789211  47 PGEPDCLYYMRTGSCSYGSNCRFNHPV 73
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
139-160 6.46e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 45.26  E-value: 6.46e-07
                          10        20
                  ....*....|....*....|..
gi 1279789211 139 CSYYLRTGSCKFGVSCKFNHPQ 160
Cdd:pfam00642   6 CRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
320-345 8.57e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 42.18  E-value: 8.57e-06
                          10        20
                  ....*....|....*....|....*.
gi 1279789211 320 PGQAVCSYYSMYGLCKYGPSCKFDHP 345
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
ZnF_C3H1 smart00356
zinc finger;
279-303 2.64e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.99  E-value: 2.64e-04
                           10        20
                   ....*....|....*....|....*
gi 1279789211  279 QPECRYFMNnGTCKYGSDCKFHHPK 303
Cdd:smart00356   4 TELCKFFKR-GYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
90-115 4.57e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.22  E-value: 4.57e-04
                           10        20
                   ....*....|....*....|....*.
gi 1279789211   90 GQPDCEYFlKTGTCKYGGSCKYHHPR 115
Cdd:smart00356   3 KTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
319-345 6.69e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.84  E-value: 6.69e-04
                           10        20
                   ....*....|....*....|....*..
gi 1279789211  319 RPGQAVCSYYsMYGLCKYGPSCKFDHP 345
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHP 26
COG5152 COG5152
Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers [General function ...
 91-121 8.45e-04

Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers [General function prediction only];


Pssm-ID: 227481 [Multi-domain]  Cd Length: 259  Bit Score: 40.83  E-value: 8.45e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1279789211  91 QPD-CEYFLKTGTCKYGGSCKYHHPRDRRGAG 121
Cdd:COG5152   140 QPDvCKDYKETGYCGYGDSCKFLHDRSDFKTG 171
ZnF_C3H1 smart00356
zinc finger;
46-72 2.92e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 34.91  E-value: 2.92e-03
                           10        20
                   ....*....|....*....|....*..
gi 1279789211   46 RPGEPDCLYYmRTGSCSYGSNCRFNHP 72
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHP 26
zf_CCCH_4 pfam18345
Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...
 282-301 3.26e-03

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.


Pssm-ID: 465719 [Multi-domain]  Cd Length: 19  Bit Score: 34.70  E-value: 3.26e-03
                          10        20
                  ....*....|....*....|
gi 1279789211 282 CRYFMNnGTCKYGSDCKFHH 301
Cdd:pfam18345   1 CKFFLK-GRCRYGDKCRFAH 19
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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