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Conserved domains on  [gi|1279841338|ref|XP_022931187|]
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uncharacterized protein LOC111437445 [Cucurbita moschata]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 14-107 5.70e-40

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


:

Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 130.18  E-value: 5.70e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279841338  14 KILRGDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNLVKKHIKQGQGH-EGGIFTVEAPLHVSNVQVVDPATGKPCKV 92
Cdd:COG0198     4 KIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNpQGGIIEKEAPIHISNVMLVDPKTGKPTRV 83

                          90
                  ....*....|....*
gi 1279841338  93 GVRYLEDGSKVRVSR 107
Cdd:COG0198    84 GFKVLEDGKKVRVCK 98
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 14-107 5.70e-40

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 130.18  E-value: 5.70e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279841338  14 KILRGDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNLVKKHIKQGQGH-EGGIFTVEAPLHVSNVQVVDPATGKPCKV 92
Cdd:COG0198     4 KIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNpQGGIIEKEAPIHISNVMLVDPKTGKPTRV 83

                          90
                  ....*....|....*
gi 1279841338  93 GVRYLEDGSKVRVSR 107
Cdd:COG0198    84 GFKVLEDGKKVRVCK 98
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 14-116 3.65e-30

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 105.43  E-value: 3.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279841338  14 KILRGDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNLVKKHIK-QGQGHEGGIFTVEAPLHVSNVQVVDPATGKPCKV 92
Cdd:TIGR01079   2 KIKKGDTVKVISGKDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKpVPANRQGGIIEKEAPIHISNVMLFDPKTGKATRV 81

                          90       100
                  ....*....|....*....|....
gi 1279841338  93 GVRYLEDGSKVRVSRgigASGSII 116
Cdd:TIGR01079  82 GYRFEEDGKKVRVFK---KNGEII 102
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 18-81 2.57e-21

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 81.41  E-value: 2.57e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1279841338  18 GDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNLVKKHIKQGQ-GHEGGIFTVEAPLHVSNVQV 81
Cdd:cd06089     1 GDEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQeNPQGGIIEVEAPIHISNVML 65
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 51-107 1.35e-19

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 77.10  E-value: 1.35e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1279841338  51 NLVKKHIKQGQ-GHEGGIFTVEAPLHVSNVQVVDPATGKPCKVGvrYLEDGSKVRVSR 107
Cdd:pfam17136   2 NMVKKHVKPSQqNPQGGIIEKEAPIHVSNVMLVDPKCGKPTRVG--FKEDGKKVRVSK 57
rpl24 CHL00141
ribosomal protein L24; Validated
 17-84 1.18e-16

ribosomal protein L24; Validated


Pssm-ID: 214374  Cd Length: 83  Bit Score: 70.06  E-value: 1.18e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279841338  17 RGDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNLVKKHIKQGQGHEGG-IFTVEAPLHVSNVQVVDP 84
Cdd:CHL00141   11 IGDTVKIISGSDKGKIGEVLKIIKKSNKVIVKGINIKFKHIKPNKENEVGeIKQFEAPIHSSNVMLYNE 79
KOW smart00739
KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.
 14-40 9.66e-04

KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.


Pssm-ID: 128978  Cd Length: 28  Bit Score: 35.00  E-value: 9.66e-04
                           10        20
                   ....*....|....*....|....*..
gi 1279841338   14 KILRGDNVMIIRGKDKGETGVIKRVIR 40
Cdd:smart00739   1 KFEVGDTVRVIAGPFKGKVGKVLEVDG 27
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 14-107 5.70e-40

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 130.18  E-value: 5.70e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279841338  14 KILRGDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNLVKKHIKQGQGH-EGGIFTVEAPLHVSNVQVVDPATGKPCKV 92
Cdd:COG0198     4 KIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNpQGGIIEKEAPIHISNVMLVDPKTGKPTRV 83

                          90
                  ....*....|....*
gi 1279841338  93 GVRYLEDGSKVRVSR 107
Cdd:COG0198    84 GFKVLEDGKKVRVCK 98
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 14-116 3.65e-30

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 105.43  E-value: 3.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279841338  14 KILRGDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNLVKKHIK-QGQGHEGGIFTVEAPLHVSNVQVVDPATGKPCKV 92
Cdd:TIGR01079   2 KIKKGDTVKVISGKDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKpVPANRQGGIIEKEAPIHISNVMLFDPKTGKATRV 81

                          90       100
                  ....*....|....*....|....
gi 1279841338  93 GVRYLEDGSKVRVSRgigASGSII 116
Cdd:TIGR01079  82 GYRFEEDGKKVRVFK---KNGEII 102
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 18-81 2.57e-21

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 81.41  E-value: 2.57e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1279841338  18 GDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNLVKKHIKQGQ-GHEGGIFTVEAPLHVSNVQV 81
Cdd:cd06089     1 GDEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQeNPQGGIIEVEAPIHISNVML 65
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 51-107 1.35e-19

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 77.10  E-value: 1.35e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1279841338  51 NLVKKHIKQGQ-GHEGGIFTVEAPLHVSNVQVVDPATGKPCKVGvrYLEDGSKVRVSR 107
Cdd:pfam17136   2 NMVKKHVKPSQqNPQGGIIEKEAPIHVSNVMLVDPKCGKPTRVG--FKEDGKKVRVSK 57
rpl24 CHL00141
ribosomal protein L24; Validated
 17-84 1.18e-16

ribosomal protein L24; Validated


Pssm-ID: 214374  Cd Length: 83  Bit Score: 70.06  E-value: 1.18e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279841338  17 RGDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNLVKKHIKQGQGHEGG-IFTVEAPLHVSNVQVVDP 84
Cdd:CHL00141   11 IGDTVKIISGSDKGKIGEVLKIIKKSNKVIVKGINIKFKHIKPNKENEVGeIKQFEAPIHSSNVMLYNE 79
rplX PRK12281
50S ribosomal protein L24; Reviewed
 14-82 8.76e-16

50S ribosomal protein L24; Reviewed


Pssm-ID: 183399  Cd Length: 76  Bit Score: 67.76  E-value: 8.76e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279841338  14 KILRGDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNLVKKHIKQGQGH-EGGIFTVEAPLHVSNVQVV 82
Cdd:PRK12281    6 KVKKGDMVKVIAGDDKGKTGKVLAVLPKKNRVIVEGVKIAKKAIKPSQKNpNGGFIEKEMPIHISNVKKV 75
KOW pfam00467
KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, ...
 17-48 3.71e-06

KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, Woese) motif is found in a variety of ribosomal proteins and NusG.


Pssm-ID: 425698 [Multi-domain]  Cd Length: 32  Bit Score: 41.60  E-value: 3.71e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1279841338  17 RGDNVMIIRGKDKGETGVIKRVIRTQNRVIVE 48
Cdd:pfam00467   1 KGDVVRVIAGPFKGKVGKVVEVDDKKNRVLVE 32
rplX_A_E TIGR01080
ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and ...
 10-83 3.78e-04

ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and eukaryotic branch of the ribosomal protein L24p/L26e family. Bacterial and organellar forms are represented by related model TIGR01079. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273432  Cd Length: 114  Bit Score: 37.91  E-value: 3.78e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1279841338  10 IRHWKILRGDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNlvkkhIKQGQGHeggifTVEAPLHVSNVQVVD 83
Cdd:TIGR01080  37 KRALPIRKGDEVRIVRGDFKGHEGKVSKVDRKRYRIYVEGVT-----KEKVDGT-----EVPVPLHPSNVMITK 100
KOW smart00739
KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.
 14-40 9.66e-04

KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.


Pssm-ID: 128978  Cd Length: 28  Bit Score: 35.00  E-value: 9.66e-04
                           10        20
                   ....*....|....*....|....*..
gi 1279841338   14 KILRGDNVMIIRGKDKGETGVIKRVIR 40
Cdd:smart00739   1 KFEVGDTVRVIAGPFKGKVGKVLEVDG 27
KOW cd00380
KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); KOW domain is known ...
 18-58 7.47e-03

KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. The KOW motif contains an invariants glycine residue and comprises alternating blocks of hydrophilic and hydrophobic residues.


Pssm-ID: 240504  Cd Length: 49  Bit Score: 32.96  E-value: 7.47e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1279841338  18 GDNVMIIRGKDKGETGVIKRVIRTQNRVIVEGKNLVKKHIK 58
Cdd:cd00380     1 GDVVRVLRGPYKGREGVVVDIDPRFGIVTVKGATGSKGAEL 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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