|
Name |
Accession |
Description |
Interval |
E-value |
| Mesothelin |
pfam06060 |
Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin); This family consists of ... |
12688-13168 |
1.70e-34 |
|
Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin); This family consists of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known.
Pssm-ID: 368727 Cd Length: 624 Bit Score: 144.99 E-value: 1.70e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 12688 TQEQALVLFSSVASVSqDTEELSVPVLQGFSCTSVQTVSTQKVKQMVRSCRHRpgrsKVQLQESQLMCM----NNYVKDE 12763
Cdd:pfam06060 41 TSQEAALLDPVLANAS-NFASLSPGLLLGFTCAEVSGLSMEHAKELAMAVRQK----NITLRGDQLRCLarrlPRHLTPE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 12764 PLSSFsdlPAEVLLYYSYDNVQ-PVNCRSYFSAVGQADYSVLSSVLNKPAALFANARSCLGITGNSLSKDQIAVLGNLTC 12842
Cdd:pfam06060 116 DLNAL---PLDLLLFLNPAMFSgPQACAHFFSLISKANVDVLPRRSPERQRLLPAALACQGVQGSQVSEADVRALGGLAC 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 12843 TLDPVYIPNSDPSIIESLKNCV-ELSDAQISAVQRLLLSGNTSYGNSSTWGQQTLQRLAKIPLYFTNSFWSlfsaTVKKN 12921
Cdd:pfam06060 193 DLPGKFVARSAEVLLPRLAGCPgPLDQDQQEAVRAVLQGGGTPYGPPSKWSVSTLDALQSLLAVLDQSIIQ----SIPKG 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 12922 FMTTFMPYL-RSINTDKTKLKTLfsncnsglsRSRLSRST---ACTVGNITAATIADPSFplgYTVDQFDACLEpGVLkd 12997
Cdd:pfam06060 269 VKAAWLQHIsRDPSGRGPELTVI---------LPRFRRDTekkACPPGKEPYVVDEDLIF---YQNWELEACVD-GAL-- 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 12998 tLTAVAQKVDDSSFQRVILN----KLKQVYPAGLADGVVKDLGSVSRQASVQEISSWNISSLDTLATLMDKSNGNWSTAQ 13073
Cdd:pfam06060 334 -LATQMDRVNAIPFTYEQLNifkhKLDKTYPQGYPESLIQHLGHFFLYMSPEDIHKWNVTSLDTVKALLKVSKGQKMDAQ 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 13074 SQQVILRYLSVKGNsLGSNELNIIK----SSLCSLNISTLQNITPAVLRNAKALDLSSCSSEQQSVLYITANSSFraQLS 13149
Cdd:pfam06060 413 AAALIARYLKGGGQ-LDKDTLDALAdfhpTYLCDFSPEQLGSVPPSVIWAVRPQDLDTCSQRQLDVLYPKAHLAF--QNV 489
|
490
....*....|....*....
gi 1207107957 13150 NGPAYYHMISPYLGMSNLE 13168
Cdd:pfam06060 490 SGLEYFEKIQPFLGGASTE 508
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
11090-11429 |
1.61e-13 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 79.43 E-value: 1.61e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11090 TASPTMPS-----TAPSTVAPPTVLSTLPYTMPPTSPNTVPPISPPT-----ATPTMPSTTPSTVSQTAPATTPhtvPPT 11159
Cdd:pfam03154 143 STSPSIPSpqdneSDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPgttqaATAGPTPSAPSVPPQGSPATSQ---PPN 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11160 LPytVPPTSPNTVPSISPTTAPPTTSSTEPPMLPYTMP-PTALNTATAIAPPTASPTMPSITPSTVPPTAPPT------- 11231
Cdd:pfam03154 220 QT--QSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPpPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQhpvppqp 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11232 TAPTVPPTLPYTVPPTSPNTVPPIAPTTAPPTTSSTVPPTLP---YTMPPTALNTATVIAPPTssptmasTTLSMVAPTA 11308
Cdd:pfam03154 298 FPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPpreQPLPPAPLSMPHIKPPPT-------TPIPQLPNPQ 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11309 PPTTPPTAPPTLPYTM-----PPTALNTATAIA---PPTASPTMPSITPSTVAATAPPTTLPY-----SMPPTAKNtvpp 11375
Cdd:pfam03154 371 SHKHPPHLSGPSPFQMnsnlpPPPALKPLSSLSthhPPSAHPPPLQLMPQSQQLPPPPAQPPVltqsqSLPPPAAS---- 446
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1207107957 11376 iapptatptlpsTTPSTVPPTATTTTLSTVPPTLPSTTPSTVPPTAPPTVSPTA 11429
Cdd:pfam03154 447 ------------HPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSA 488
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
11028-11428 |
1.06e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 76.90 E-value: 1.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11028 PYTMPPTFPNTVPPISPSTATPTMPSTTPFTVPPTTAPTAPPTLPYTMPPTALNTVTVIAPLTASPTMPSTAPStvAPPT 11107
Cdd:PHA03247 2614 PSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRA--ARPT 2691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11108 VLSTLPYTMPPTSPNTvPPISPPTATPTMPSTT-PSTVSQTAPATTPHTVPPTLPY-TVPPTSPNTVPSispTTAPPTTS 11185
Cdd:PHA03247 2692 VGSLTSLADPPPPPPT-PEPAPHALVSATPLPPgPAAARQASPALPAAPAPPAVPAgPATPGGPARPAR---PPTTAGPP 2767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11186 STEPPMLPYTMPPTALnTATAIAPPTAS----PTMPSITPSTVPPTAPPTTAPTVPPTLPYTVPPTSPntvppiapttap 11261
Cdd:PHA03247 2768 APAPPAAPAAGPPRRL-TRPAVASLSESreslPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSA------------ 2834
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11262 pttsSTVPPTLPYTMPPTALNTATVIAP-------PTSSPTMASTTLSMVAPTAPPTTPPTAPPTLPYTMPPTalntata 11334
Cdd:PHA03247 2835 ----QPTAPPPPPGPPPPSLPLGGSVAPggdvrrrPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPD------- 2903
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11335 iaPPTASPTMPSITPSTVAATAPPTTLPYSMPPTAKNTVPPIAPPTATPTLPSTTPSTVPPTATTTTLSTVPPT---LPS 11411
Cdd:PHA03247 2904 --QPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPrfrVPQ 2981
|
410
....*....|....*..
gi 1207107957 11412 TTPStVPPTAPPTVSPT 11428
Cdd:PHA03247 2982 PAPS-REAPASSTPPLT 2997
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
10845-11218 |
6.43e-10 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 67.48 E-value: 6.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10845 PTALNTATVIAPPtASPTMPSTTlstvaptappttpptvpsTLPYTMPPTSSNTVPP-ISPPTATP---TMPSTVPPTAP 10920
Cdd:pfam03154 171 PPVLQAQSGAASP-PSPPPPGTT------------------QAATAGPTPSAPSVPPqGSPATSQPpnqTQSTAAPHTLI 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10921 PTTPPTAPPTLPYTMPPTSPNTAPPIASPTATPTMPSTTPTTIPPTAPPTTPPTVPPTLPYTMP-PTALNTATAIATPTA 10999
Cdd:pfam03154 232 QQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPqPFPLTPQSSQSQVPP 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11000 SPTMPSTTLSTVAPTAPPTTPPTVPSTLPYTMP-PTFPNTVPPISPSTATPTmpSTTPFTVPPTTAPTAPPTLPYTM--- 11075
Cdd:pfam03154 312 GPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPlPPAPLSMPHIKPPPTTPI--PQLPNPQSHKHPPHLSGPSPFQMnsn 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11076 --PPTALNtvtviaPLTASPTmpSTAPSTVAPPTVLstlpytMPPTSPNTVPPISPPTATPTmpSTTPSTVSQTAPATTP 11153
Cdd:pfam03154 390 lpPPPALK------PLSSLST--HHPPSAHPPPLQL------MPQSQQLPPPPAQPPVLTQS--QSLPPPAASHPPTSGL 453
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1207107957 11154 HTVPPTLPYTVPPTSPNTVPSISpttappttsstePPMLPytmPPTALNTATAIAPPTASPTMPS 11218
Cdd:pfam03154 454 HQVPSQSPFPQHPFVPGGPPPIT------------PPSGP---PTSTSSAMPGIQPPSSASVSSS 503
|
|
| KLF17_N |
cd21574 |
N-terminal domain of Kruppel-like factor 17; Kruppel-like factor 17 (KLF17), or Krueppel-like ... |
11091-11199 |
3.82e-05 |
|
N-terminal domain of Kruppel-like factor 17; Kruppel-like factor 17 (KLF17), or Krueppel-like factor 17, is a protein that, in humans, is encoded by the KLF17 gene and acts as a tumor suppressor. It negatively regulates epithelial-mesenchymal transition and metastasis in breast cancer. KLF17 is thought to be the human ortholog of the mouse gene, zinc finger protein 393 (Zfp393), although it has diverged significantly. KLF17 can regulate gene transcription from CACCC-box elements. It belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF17.
Pssm-ID: 410567 Cd Length: 286 Bit Score: 50.46 E-value: 3.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11091 ASPTMPSTAPSTvapPTVlsTLPYTMPPTSPNTVPPISPPTATPTMPsttpstvsqtapattpHTVPPTLPYTVPPTSPN 11170
Cdd:cd21574 122 GPQMMPLGEPNI---PGV--AMTFSGNLRMPPSGLPVSASSGIPMMS----------------HIRAPTMPYSGPPTVPS 180
|
90 100 110
....*....|....*....|....*....|
gi 1207107957 11171 TVPSISpttappttsstePPM-LPYTMPPT 11199
Cdd:cd21574 181 NRDSLT------------PKMlLAPTMPST 198
|
|
| Chi1 |
COG3469 |
Chitinase [Carbohydrate transport and metabolism]; |
11029-11217 |
4.58e-05 |
|
Chitinase [Carbohydrate transport and metabolism];
Pssm-ID: 442692 [Multi-domain] Cd Length: 534 Bit Score: 51.29 E-value: 4.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11029 YTMPPTFPNTVPPISPSTATPTMPSTTPFTVPPTTAPTAPPTLPYTMPPTALNTVTVIAPLTASPTMPSTAPSTVAPPTV 11108
Cdd:COG3469 22 LLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATLVATST 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11109 LSTLPYtmpPTSPNTVPPISPPTATPTMPSTTPSTVSQTAPATTPHTVPPTLPYTVPPTSPNTVPSISPTTAPPTTSSTE 11188
Cdd:COG3469 102 ASGANT---GTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSGTETATGGTTTTSTTTTTTSASTT 178
|
170 180
....*....|....*....|....*....
gi 1207107957 11189 PPMLPYTMPPTALNTATAIAPPTASPTMP 11217
Cdd:COG3469 179 PSATTTATATTASGATTPSATTTATTTGP 207
|
|
| half-pint |
TIGR01645 |
poly-U binding splicing factor, half-pint family; The proteins represented by this model ... |
11079-11219 |
3.95e-03 |
|
poly-U binding splicing factor, half-pint family; The proteins represented by this model contain three RNA recognition motifs (rrm: pfam00076) and have been characterized as poly-pyrimidine tract binding proteins associated with RNA splicing factors. In the case of PUF60 (GP|6176532), in complex with p54, and in the presence of U2AF, facilitates association of U2 snRNP with pre-mRNA.
Pssm-ID: 130706 [Multi-domain] Cd Length: 612 Bit Score: 45.06 E-value: 3.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11079 ALNTVTVIAPLTASPTMPSTA-------PSTVAPPTVLSTLPYTMPPTSPNTVPPISPPTATPTMPSTTPstvsqtapat 11151
Cdd:TIGR01645 317 AVAGAAVLGPRAQSPATPSSSlptdignKAVVSSAKKEAEEVPPLPQAAPAVVKPGPMEIPTPVPPPGLA---------- 386
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1207107957 11152 TPHTVPPtlPYTVPPTSPNtvPSISPTTAPPTTSSTEPPMLPYTMPPTALNTATAIAPPTASPTMPSI 11219
Cdd:TIGR01645 387 IPSLVAP--PGLVAPTEIN--PSFLASPRKKMKREKLPVTFGALDDTLAWKEPSKEDQTSEDGKMLAI 450
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Mesothelin |
pfam06060 |
Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin); This family consists of ... |
12688-13168 |
1.70e-34 |
|
Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin); This family consists of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known.
Pssm-ID: 368727 Cd Length: 624 Bit Score: 144.99 E-value: 1.70e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 12688 TQEQALVLFSSVASVSqDTEELSVPVLQGFSCTSVQTVSTQKVKQMVRSCRHRpgrsKVQLQESQLMCM----NNYVKDE 12763
Cdd:pfam06060 41 TSQEAALLDPVLANAS-NFASLSPGLLLGFTCAEVSGLSMEHAKELAMAVRQK----NITLRGDQLRCLarrlPRHLTPE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 12764 PLSSFsdlPAEVLLYYSYDNVQ-PVNCRSYFSAVGQADYSVLSSVLNKPAALFANARSCLGITGNSLSKDQIAVLGNLTC 12842
Cdd:pfam06060 116 DLNAL---PLDLLLFLNPAMFSgPQACAHFFSLISKANVDVLPRRSPERQRLLPAALACQGVQGSQVSEADVRALGGLAC 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 12843 TLDPVYIPNSDPSIIESLKNCV-ELSDAQISAVQRLLLSGNTSYGNSSTWGQQTLQRLAKIPLYFTNSFWSlfsaTVKKN 12921
Cdd:pfam06060 193 DLPGKFVARSAEVLLPRLAGCPgPLDQDQQEAVRAVLQGGGTPYGPPSKWSVSTLDALQSLLAVLDQSIIQ----SIPKG 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 12922 FMTTFMPYL-RSINTDKTKLKTLfsncnsglsRSRLSRST---ACTVGNITAATIADPSFplgYTVDQFDACLEpGVLkd 12997
Cdd:pfam06060 269 VKAAWLQHIsRDPSGRGPELTVI---------LPRFRRDTekkACPPGKEPYVVDEDLIF---YQNWELEACVD-GAL-- 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 12998 tLTAVAQKVDDSSFQRVILN----KLKQVYPAGLADGVVKDLGSVSRQASVQEISSWNISSLDTLATLMDKSNGNWSTAQ 13073
Cdd:pfam06060 334 -LATQMDRVNAIPFTYEQLNifkhKLDKTYPQGYPESLIQHLGHFFLYMSPEDIHKWNVTSLDTVKALLKVSKGQKMDAQ 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 13074 SQQVILRYLSVKGNsLGSNELNIIK----SSLCSLNISTLQNITPAVLRNAKALDLSSCSSEQQSVLYITANSSFraQLS 13149
Cdd:pfam06060 413 AAALIARYLKGGGQ-LDKDTLDALAdfhpTYLCDFSPEQLGSVPPSVIWAVRPQDLDTCSQRQLDVLYPKAHLAF--QNV 489
|
490
....*....|....*....
gi 1207107957 13150 NGPAYYHMISPYLGMSNLE 13168
Cdd:pfam06060 490 SGLEYFEKIQPFLGGASTE 508
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
11090-11429 |
1.61e-13 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 79.43 E-value: 1.61e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11090 TASPTMPS-----TAPSTVAPPTVLSTLPYTMPPTSPNTVPPISPPT-----ATPTMPSTTPSTVSQTAPATTPhtvPPT 11159
Cdd:pfam03154 143 STSPSIPSpqdneSDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPgttqaATAGPTPSAPSVPPQGSPATSQ---PPN 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11160 LPytVPPTSPNTVPSISPTTAPPTTSSTEPPMLPYTMP-PTALNTATAIAPPTASPTMPSITPSTVPPTAPPT------- 11231
Cdd:pfam03154 220 QT--QSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPpPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQhpvppqp 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11232 TAPTVPPTLPYTVPPTSPNTVPPIAPTTAPPTTSSTVPPTLP---YTMPPTALNTATVIAPPTssptmasTTLSMVAPTA 11308
Cdd:pfam03154 298 FPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPpreQPLPPAPLSMPHIKPPPT-------TPIPQLPNPQ 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11309 PPTTPPTAPPTLPYTM-----PPTALNTATAIA---PPTASPTMPSITPSTVAATAPPTTLPY-----SMPPTAKNtvpp 11375
Cdd:pfam03154 371 SHKHPPHLSGPSPFQMnsnlpPPPALKPLSSLSthhPPSAHPPPLQLMPQSQQLPPPPAQPPVltqsqSLPPPAAS---- 446
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1207107957 11376 iapptatptlpsTTPSTVPPTATTTTLSTVPPTLPSTTPSTVPPTAPPTVSPTA 11429
Cdd:pfam03154 447 ------------HPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSA 488
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
11028-11428 |
1.06e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 76.90 E-value: 1.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11028 PYTMPPTFPNTVPPISPSTATPTMPSTTPFTVPPTTAPTAPPTLPYTMPPTALNTVTVIAPLTASPTMPSTAPStvAPPT 11107
Cdd:PHA03247 2614 PSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRA--ARPT 2691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11108 VLSTLPYTMPPTSPNTvPPISPPTATPTMPSTT-PSTVSQTAPATTPHTVPPTLPY-TVPPTSPNTVPSispTTAPPTTS 11185
Cdd:PHA03247 2692 VGSLTSLADPPPPPPT-PEPAPHALVSATPLPPgPAAARQASPALPAAPAPPAVPAgPATPGGPARPAR---PPTTAGPP 2767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11186 STEPPMLPYTMPPTALnTATAIAPPTAS----PTMPSITPSTVPPTAPPTTAPTVPPTLPYTVPPTSPntvppiapttap 11261
Cdd:PHA03247 2768 APAPPAAPAAGPPRRL-TRPAVASLSESreslPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSA------------ 2834
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11262 pttsSTVPPTLPYTMPPTALNTATVIAP-------PTSSPTMASTTLSMVAPTAPPTTPPTAPPTLPYTMPPTalntata 11334
Cdd:PHA03247 2835 ----QPTAPPPPPGPPPPSLPLGGSVAPggdvrrrPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPD------- 2903
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11335 iaPPTASPTMPSITPSTVAATAPPTTLPYSMPPTAKNTVPPIAPPTATPTLPSTTPSTVPPTATTTTLSTVPPT---LPS 11411
Cdd:PHA03247 2904 --QPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPrfrVPQ 2981
|
410
....*....|....*..
gi 1207107957 11412 TTPStVPPTAPPTVSPT 11428
Cdd:PHA03247 2982 PAPS-REAPASSTPPLT 2997
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
11030-11439 |
6.22e-12 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 74.03 E-value: 6.22e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11030 TMPPTFPNTVPPISPSTATPTMPSTTPFTvppttaptapptlpyTMPPTALNTVTVIAPLTASPtmPSTAPSTVAPPTVL 11109
Cdd:pfam03154 169 TQPPVLQAQSGAASPPSPPPPGTTQAATA---------------GPTPSAPSVPPQGSPATSQP--PNQTQSTAAPHTLI 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11110 STLPYTMPPTSPNTVPPISPPTATPTMPSTTPSTVS---------------QTAPATTPHTVPPTlPYTVP--------P 11166
Cdd:pfam03154 232 QQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPqpslhgqmppmphslQTGPSHMQHPVPPQ-PFPLTpqssqsqvP 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11167 TSPNT---VPSISPTTAPPTTSSTEPPMLPYTMP-PTALNTATAIAPPtasPTMPsitpstvpptappttaptvpptlpy 11242
Cdd:pfam03154 311 PGPSPaapGQSQQRIHTPPSQSQLQSQQPPREQPlPPAPLSMPHIKPP---PTTP------------------------- 362
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11243 tVPPTsPNTVPPIAPTTAPPTTSSTVPPTLPytmPPTALNTATVIA---PPTSSPtmasTTLSMVAPTAPPTTPPTAPPT 11319
Cdd:pfam03154 363 -IPQL-PNPQSHKHPPHLSGPSPFQMNSNLP---PPPALKPLSSLSthhPPSAHP----PPLQLMPQSQQLPPPPAQPPV 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11320 LPYT--MPPTALNtataiAPPTAS----PTMPSITPSTVAATAPPTTLPYSMPPTAKNTVPPIAPPtatptlpsttpstv 11393
Cdd:pfam03154 434 LTQSqsLPPPAAS-----HPPTSGlhqvPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAMPGIQP-------------- 494
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1207107957 11394 pptattttlstvPPTLPSTTPSTVPPTAPPTVSPTAVCEETLIDEE 11439
Cdd:pfam03154 495 ------------PSSASVSSSGPVPAAVSCPLPPVQIKEEALDEAE 528
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
11032-11361 |
1.91e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 69.58 E-value: 1.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11032 PPTFPNTVP-PISPSTATPTMPSTTPFTVPPTTAPTAPptlpytmPPTALNTVTVIAPLT-ASPTMPSTAPSTVAPPTVL 11109
Cdd:PHA03247 2704 PPPTPEPAPhALVSATPLPPGPAAARQASPALPAAPAP-------PAVPAGPATPGGPARpARPPTTAGPPAPAPPAAPA 2776
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11110 STLPYTMPPTSPNTVPPISPPTATPTMPSTTPSTVSQTAPATTPHTVP-PTLPytvPPTSPntVPSispttappttsste 11188
Cdd:PHA03247 2777 AGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPaGPLP---PPTSA--QPT-------------- 2837
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11189 PPMLPYTMPPTALNTATAIAP-------PTASPTMPSITPSTVPPTAPPTTAPTVPPTLPYTVPPTSPNTVPPIAPTTAP 11261
Cdd:PHA03247 2838 APPPPPGPPPPSLPLGGSVAPggdvrrrPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPP 2917
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11262 PTTSSTVPPTLPYTMPPTALNTATVIAPPTSspTMASTTLSMVAPTAPPTTPPTAPPTLPYTMPPTALNTATAIAPPTAS 11341
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPPPRPQPPLAPTTD--PAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPP 2995
|
330 340
....*....|....*....|....*....
gi 1207107957 11342 PT---MPSITP--STVA----ATAPPTTL 11361
Cdd:PHA03247 2996 LTghsLSRVSSwaSSLAlheeTDPPPVSL 3024
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
10845-11218 |
6.43e-10 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 67.48 E-value: 6.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10845 PTALNTATVIAPPtASPTMPSTTlstvaptappttpptvpsTLPYTMPPTSSNTVPP-ISPPTATP---TMPSTVPPTAP 10920
Cdd:pfam03154 171 PPVLQAQSGAASP-PSPPPPGTT------------------QAATAGPTPSAPSVPPqGSPATSQPpnqTQSTAAPHTLI 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10921 PTTPPTAPPTLPYTMPPTSPNTAPPIASPTATPTMPSTTPTTIPPTAPPTTPPTVPPTLPYTMP-PTALNTATAIATPTA 10999
Cdd:pfam03154 232 QQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPqPFPLTPQSSQSQVPP 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11000 SPTMPSTTLSTVAPTAPPTTPPTVPSTLPYTMP-PTFPNTVPPISPSTATPTmpSTTPFTVPPTTAPTAPPTLPYTM--- 11075
Cdd:pfam03154 312 GPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPlPPAPLSMPHIKPPPTTPI--PQLPNPQSHKHPPHLSGPSPFQMnsn 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11076 --PPTALNtvtviaPLTASPTmpSTAPSTVAPPTVLstlpytMPPTSPNTVPPISPPTATPTmpSTTPSTVSQTAPATTP 11153
Cdd:pfam03154 390 lpPPPALK------PLSSLST--HHPPSAHPPPLQL------MPQSQQLPPPPAQPPVLTQS--QSLPPPAASHPPTSGL 453
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1207107957 11154 HTVPPTLPYTVPPTSPNTVPSISpttappttsstePPMLPytmPPTALNTATAIAPPTASPTMPS 11218
Cdd:pfam03154 454 HQVPSQSPFPQHPFVPGGPPPIT------------PPSGP---PTSTSSAMPGIQPPSSASVSSS 503
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
10890-11372 |
1.28e-09 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 66.33 E-value: 1.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10890 TMPPTSSNTVPPISPPtatptmpstvpptappTTPPTAPPTLPYTMPPTSPNTAPPIASptatptmpsttpttipptapp 10969
Cdd:pfam03154 169 TQPPVLQAQSGAASPP----------------SPPPPGTTQAATAGPTPSAPSVPPQGS--------------------- 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10970 ttpptvpptlpytmPPTAlntataiatptASPTMPSTTLSTVAPTAPPttpptvpstlPYTMPPTFPNTVPPISPSTATP 11049
Cdd:pfam03154 212 --------------PATS-----------QPPNQTQSTAAPHTLIQQT----------PTLHPQRLPSPHPPLQPMTQPP 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11050 tmpsttpftvppttaptapptlpytmPPTALNTVTVIAPLTASPTMPSTAPSTVAPPTV---LSTLPYTMPPTSPNTVPP 11126
Cdd:pfam03154 257 --------------------------PPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMqhpVPPQPFPLTPQSSQSQVP 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11127 ISPPTA-------TPTMPSTTPSTVSQTAPATTPhtVPP---TLPYTV-PPTSPntVPSISPTTAPPTTSSTEPPMlPYT 11195
Cdd:pfam03154 311 PGPSPAapgqsqqRIHTPPSQSQLQSQQPPREQP--LPPaplSMPHIKpPPTTP--IPQLPNPQSHKHPPHLSGPS-PFQ 385
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11196 M-----PPTALNTATAIA---PPTASPtmPSITPSTVPPTAPPTTAPTVPPTLPYTVPPTSPNtvppiaptTAPPTTSST 11267
Cdd:pfam03154 386 MnsnlpPPPALKPLSSLSthhPPSAHP--PPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAAS--------HPPTSGLHQ 455
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11268 VPPTLPYTMPPTALNTATVIAPPTSSPTmaSTTLSMVAPTAPPTTPPTAPPTLPytmpptalNTATAIAPPTASPTMPSI 11347
Cdd:pfam03154 456 VPSQSPFPQHPFVPGGPPPITPPSGPPT--STSSAMPGIQPPSSASVSSSGPVP--------AAVSCPLPPVQIKEEALD 525
|
490 500
....*....|....*....|....*
gi 1207107957 11348 TPSTVAATAPPTTLPySMPPTAKNT 11372
Cdd:pfam03154 526 EAEEPESPPPPPRSP-SPEPTVVNT 549
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
11036-11372 |
2.01e-09 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 65.71 E-value: 2.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11036 PNTVPPISPSTATPTMPSTTPFTVPPTTAPTAPPtlpytmpPTALNTVTVIAPLTASPTMPSTAPSTVAPPTVLSTLPYT 11115
Cdd:pfam05109 442 PNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTS-------PTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVT 514
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11116 MPptSPNTVPPiSPPTATPTmPSTTPSTVSQTAPAT-----TPHTVPPTlPYTVPPTSPNTVPSispttappttsstepp 11190
Cdd:pfam05109 515 TP--TPNATSP-TPAVTTPT-PNATSPTLGKTSPTSavttpTPNATSPT-PAVTTPTPNATIPT---------------- 573
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11191 mLPYTMPPTALNTataiapPTASPTMPSITPSTVPPTAPPTTAPTVPPTLPYTVPP---TSPNTVPPIAPTTAPPTTSST 11267
Cdd:pfam05109 574 -LGKTSPTSAVTT------PTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPknaTSAVTTGQHNITSSSTSSMSL 646
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11268 VPPTLPYTMPPTALNTATVIAP-PTSSPTMASTTLSMVAPTAPPTTPPTAPPtlPYTMPPTalnTATAIAPPTASptmPS 11346
Cdd:pfam05109 647 RPSSISETLSPSTSDNSTSHMPlLTSAHPTGGENITQVTPASTSTHHVSTSS--PAPRPGT---TSQASGPGNSS---TS 718
|
330 340
....*....|....*....|....*...
gi 1207107957 11347 ITPSTVAAT--APPTTLPYSMPPTAKNT 11372
Cdd:pfam05109 719 TKPGEVNVTkgTPPKNATSPQAPSGQKT 746
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
11028-11458 |
2.09e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 66.12 E-value: 2.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11028 PYTMPPTFPNTVPPisPSTATPTMPSTTPFTVppttaptapptlpyTMPPTALntvTVIAPLTASPTMPSTAPSTVAPPT 11107
Cdd:PHA03247 2498 PGGGGPPDPDAPPA--PSRLAPAILPDEPVGE--------------PVHPRML---TWIRGLEELASDDAGDPPPPLPPA 2558
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11108 VLstlpytmPPTSPNTVPPiSPPTATPTMPSTT-----PSTVSQTAPATTPHTVPPTLPYTVPPTSPNTVPSispttapp 11182
Cdd:PHA03247 2559 AP-------PAAPDRSVPP-PRPAPRPSEPAVTsrarrPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTH-------- 2622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11183 ttsstePPMLPYTMPPTALNTATAIAPPTASPTMPSITPSTVPPTAPPTTAPTVPPTLPYTVPPTSPNtvppiapttapp 11262
Cdd:PHA03247 2623 ------APDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPR------------ 2684
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11263 ttsstvPPTLPYTMPPTAlNTATVIAP---PTSSPTMASTTLSMVAPTAPPTTPPTAPPTLPYTmPPTALNTATAIAP-P 11338
Cdd:PHA03247 2685 ------RRAARPTVGSLT-SLADPPPPpptPEPAPHALVSATPLPPGPAAARQASPALPAAPAP-PAVPAGPATPGGPaR 2756
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11339 TASPTMPSITPSTVAATAPPTTLPYSMPPTAKNTVPPIAPPTATPTLPSTTPSTVPPTATTTTLSTVPPTlPSTTPSTVP 11418
Cdd:PHA03247 2757 PARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAG-PLPPPTSAQ 2835
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1207107957 11419 PTAPPTvsPTAVCEETLIDEERLCAGVDSEQLQTSGSVAA 11458
Cdd:PHA03247 2836 PTAPPP--PPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAA 2873
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
11079-11368 |
8.34e-09 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 63.06 E-value: 8.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11079 ALNTVTVIAPLTASPTMPSTAPSTV-----APPTVLSTLPYTMPPTSPNTVPPISPPTAT--PTMPSTTPSTVSQTAPAT 11151
Cdd:pfam17823 106 AADGAASRALAAAASSSPSSAAQSLpaaiaALPSEAFSAPRAAACRANASAAPRAAIAAAsaPHAASPAPRTAASSTTAA 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11152 TPHTVPPTLPYTVPPTSPNTVPSISPTTAPPTTssteppmlpyTMPPtALNTATAiAPPTASPTMPSITPSTVpptappt 11231
Cdd:pfam17823 186 SSTTAASSAPTTAASSAPATLTPARGISTAATA----------TGHP-AAGTALA-AVGNSSPAAGTVTAAVG------- 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11232 taptvpptlpyTVPPTSPNTVPPIAPTTAPPTTSSTVPPTLPYTMPPT--------ALNTATVIAPPTSSPTMASTTLSM 11303
Cdd:pfam17823 247 -----------TVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAkhmpsdtmARNPAAPMGAQAQGPIIQVSTDQP 315
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1207107957 11304 VAPTAPPTTPPTAPPTLPYTMPPTALNTATAIAPPTASPTM-PSITPSTVAATA--------PPTTLPYSMPPT 11368
Cdd:pfam17823 316 VHNTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKePSASPVPVLHTSmipeveatSPTTQPSPLLPT 389
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
11076-11429 |
1.06e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.80 E-value: 1.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11076 PPTALNTV--TVIAPLTASPTMPSTAPSTVAPPTVLS-TLPYTMPPTSPNTVPPISPPTAT--PTMPSTTPSTVSQTAPA 11150
Cdd:PHA03247 2561 PAAPDRSVppPRPAPRPSEPAVTSRARRPDAPPQSARpRAPVDDRGDPRGPAPPSPLPPDThaPDPPPPSPSPAANEPDP 2640
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11151 TTPHTVPPTLPYTVPPTSPNTVPSISPTTAPPTTSSTEPPMLPytMPPTALNTATAIA--------PPTASPTMPSITPS 11222
Cdd:PHA03247 2641 HPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRP--RRRAARPTVGSLTsladppppPPTPEPAPHALVSA 2718
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11223 TVPPTAPPTTAPTVPPTLPYTVPPTSPNTvppiapttapptTSSTVPPTLPYTMPPTAlnTATVIAPPTSSPTMASTTLS 11302
Cdd:PHA03247 2719 TPLPPGPAAARQASPALPAAPAPPAVPAG------------PATPGGPARPARPPTTA--GPPAPAPPAAPAAGPPRRLT 2784
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11303 MVAPTAPPTTPPTAPPTLPYTMPPTALNTATAIAPPTASPTMPSITPSTVAATAPPTTLPYSMPPTAkntvppiapptat 11382
Cdd:PHA03247 2785 RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP------------- 2851
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1207107957 11383 ptlpsttpstvpptatttTLSTVPPTLPSttpSTVPPTAPPTVSPTA 11429
Cdd:PHA03247 2852 ------------------LGGSVAPGGDV---RRRPPSRSPAAKPAA 2877
|
|
| MISS |
pfam15822 |
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic ... |
11076-11217 |
1.66e-08 |
|
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic MAPK-interacting and spindle-stabilising protein-like proteins. MISS is rich in prolines and has four potential MAPK-phosphorylation sites, a MAPK-docking site, a PEST sequence (PEST motif) and a bipartite nuclear localization signal. The endogenous protein accumulates during mouse meiotic maturation and is found as discrete dots on the MII spindle. MISS is the first example of a physiological MAPK-substrate that is stabilized in MII that specifically regulates MII spindle integrity during the CSF arrest.
Pssm-ID: 318115 [Multi-domain] Cd Length: 238 Bit Score: 60.00 E-value: 1.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11076 PPTALNTVTV-IAPLTASPTMPSTAPSTVAPPTVLSTLPYTMPPTSP---NTVP-PISP-PTATPTMP----------ST 11139
Cdd:pfam15822 51 PSTAPSTVPFgPAPTGMYPSIPLTGPSPGPPAPFPPSGPSCPPPGGPypaPTVPgPGPIgPYPTPNMPfpelprpygaPT 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11140 TPSTVSQTAPATTPHTVP-----------PTLPYTVPPTSPNTVPSISPTTAppttsstepPMLPY-TMPPTALNTATAI 11207
Cdd:pfam15822 131 DPAAAAPSGPWGSMSSGPwapgmggqypaPNMPYPSPGPYPAVPPPQSPGAA---------PPVPWgTVPPGPWGPPAPY 201
|
170
....*....|
gi 1207107957 11208 APPTASPTMP 11217
Cdd:pfam15822 202 PDPTGSYPMP 211
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
11087-11217 |
2.91e-08 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 59.87 E-value: 2.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11087 APLTASPTMPSTAPSTVAPPTVLSTLPYTMPPTSPnTVPPISPPTATPTMPSTTPSTVSQTAPATTPHtVPPTLPYTVPP 11166
Cdd:PHA02682 80 SPLAPSPACAAPAPACPACAPAAPAPAVTCPAPAP-ACPPATAPTCPPPAVCPAPARPAPACPPSTRQ-CPPAPPLPTPK 157
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1207107957 11167 TSPNTVPSISPTTAPpttsstePPMLPYTMPPTaLNTATAiAPPTASPTMP 11217
Cdd:PHA02682 158 PAPAAKPIFLHNQLP-------PPDYPAASCPT-IETAPA-ASPVLEPRIP 199
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
11096-11369 |
5.79e-06 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 54.16 E-value: 5.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11096 PSTAPSTVAPPTVLSTLPYTMPPTSPNTVP-PISPPTA-----TPTMPSTTPSTVSQTAPATTPHTVPPTLPYTVPptSP 11169
Cdd:PLN03209 339 PKPVPTKPVTPEAPSPPIEEEPPQPKAVVPrPLSPYTAyedlkPPTSPIPTPPSSSPASSKSVDAVAKPAEPDVVP--SP 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11170 NTVPSISPTTAPPTTSSTEPPMLPYTMPPTalntataIAPPTA-SPTMPSITPStvpptappttaptvpptlpytvPPTS 11248
Cdd:PLN03209 417 GSASNVPEVEPAQVEAKKTRPLSPYARYED-------LKPPTSpSPTAPTGVSP----------------------SVSS 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11249 PNTVppiapttappttsstvpPTLPYTMPPTALNTATVIAPPTSSPtmasttLSMVAPTAPPTTPPTAPPTLPYTMPPTA 11328
Cdd:PLN03209 468 TSSV-----------------PAVPDTAPATAATDAAAPPPANMRP------LSPYAVYDDLKPPTSPSPAAPVGKVAPS 524
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1207107957 11329 LNTATAIAPPTASPTMPSITPSTVAATAPPTTlPYSM-----PPTA 11369
Cdd:PLN03209 525 STNEVVKVGNSAPPTALADEQHHAQPKPRPLS-PYTMyedlkPPTS 569
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
11033-11362 |
6.79e-06 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 53.81 E-value: 6.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11033 PTFPNTVPPISPSTATPTMPSTTPFTVPPT---TAPTAPPTLPYTMPptalnTVTVIAPLTASPTMPSTAPSTVAPP--T 11107
Cdd:pfam17823 115 LAAAASSSPSSAAQSLPAAIAALPSEAFSApraAACRANASAAPRAA-----IAAASAPHAASPAPRTAASSTTAASstT 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11108 VLSTLPYTMPPTSPNTVPPISpPTATPTMPSTTPSTVSQTAPATTPHTVPPTLPYTVPPTSPNTVPSISPTTAPPTTSST 11187
Cdd:pfam17823 190 AASSAPTTAASSAPATLTPAR-GISTAATATGHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAG 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11188 EPPM-LPYTMPP-----TALNT-ATAIAPPTASPTMPSITPSTVPPTAPPTTAPTVPPTLPYTVPPTSPNTVPPIAPTTA 11260
Cdd:pfam17823 269 TINMgDPHARRLspakhMPSDTmARNPAAPMGAQAQGPIIQVSTDQPVHNTAGEPTPSPSNTTLEPNTPKSVASTNLAVV 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11261 PPTTSSTVPPTL-PYTMPPTALNTATVIAPPTSSPTmasttlsmvaptappttpptappTLPYT-------MPPTALNTA 11332
Cdd:pfam17823 349 TTTKAQAKEPSAsPVPVLHTSMIPEVEATSPTTQPS-----------------------PLLPTqgaagpgILLAPEQVA 405
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1207107957 11333 TAIAPPTAS-------------PTMPSITPSTVAATAPPTTLP 11362
Cdd:pfam17823 406 TEATAGTASagptprssgdpktLAMASCQLSTQGQYLVVTTDP 448
|
|
| MISS |
pfam15822 |
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic ... |
11111-11373 |
7.09e-06 |
|
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic MAPK-interacting and spindle-stabilising protein-like proteins. MISS is rich in prolines and has four potential MAPK-phosphorylation sites, a MAPK-docking site, a PEST sequence (PEST motif) and a bipartite nuclear localization signal. The endogenous protein accumulates during mouse meiotic maturation and is found as discrete dots on the MII spindle. MISS is the first example of a physiological MAPK-substrate that is stabilized in MII that specifically regulates MII spindle integrity during the CSF arrest.
Pssm-ID: 318115 [Multi-domain] Cd Length: 238 Bit Score: 51.91 E-value: 7.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11111 TLPYTMPPTSP-------NTVP-------PISPPTATPTMPSTTPSTVS-QTAPATTPHTVPPTLPY-TVPPTSPntvps 11174
Cdd:pfam15822 2 SLADALPEQSPaktsavsNPKPgqppqgwPGSNPWNNPSAPPAVPSGLPpSTAPSTVPFGPAPTGMYpSIPLTGP----- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11175 ispttappttsstePPMLPYTMPPTALNtataiAPPTASPTMPSitpstvpptappttaptvpptlpyTVP---PTSPnt 11251
Cdd:pfam15822 77 --------------SPGPPAPFPPSGPS-----CPPPGGPYPAP------------------------TVPgpgPIGP-- 111
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11252 vppiapttappttssTVPPTLPYTMPPTALNTATVIAPPTSSPTMASttlsmvaptappttpptapptlpytMPPTALnt 11331
Cdd:pfam15822 112 ---------------YPTPNMPFPELPRPYGAPTDPAAAAPSGPWGS-------------------------MSSGPW-- 149
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1207107957 11332 ATAIAPPTASPTMPSITPSTVAATAPPTTlPYSMPPTAKNTV 11373
Cdd:pfam15822 150 APGMGGQYPAPNMPYPSPGPYPAVPPPQS-PGAAPPVPWGTV 190
|
|
| SAP130_C |
pfam16014 |
Histone deacetylase complex subunit SAP130 C-terminus; |
11077-11174 |
1.26e-05 |
|
Histone deacetylase complex subunit SAP130 C-terminus;
Pssm-ID: 464973 [Multi-domain] Cd Length: 371 Bit Score: 52.63 E-value: 1.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11077 PTALNTVTVIAPLTASPTMPSTAPSTVAPPTVLSTLPYTMPPTSP------NTVPPISPPTA--TPTMPSTT-------- 11140
Cdd:pfam16014 49 QTASASPPSQHPAQAIPTILAPAAPPSQPSVVLSTLPAAMAVTPPipasmaNVVAPPTQPAAssTAACAVSSvlpeikik 128
|
90 100 110
....*....|....*....|....*....|....*...
gi 1207107957 11141 ----PSTVSQTAPATTPHTVPPTLPytvPPTSPNTVPS 11174
Cdd:pfam16014 129 qeaePMDTSQSVPPLTPTSISPALT---SLANNLSVPA 163
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
11000-11215 |
1.44e-05 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 52.65 E-value: 1.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11000 SPTMPSTTLSTVAPTAPPTTPPTVPSTLPYTMPPTFPNTVPPISP------STATPTMPSTTPFTVPPTTAPTAPPTLPY 11073
Cdd:pfam17823 167 APHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGistaatATGHPAAGTALAAVGNSSPAAGTVTAAVG 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11074 TMPPTALNTVTVIA--------------PLTASPT----MPS-TAPSTVAPPT----------------VLSTLPYTMPP 11118
Cdd:pfam17823 247 TVTPAALATLAAAAgtvasaagtinmgdPHARRLSpakhMPSdTMARNPAAPMgaqaqgpiiqvstdqpVHNTAGEPTPS 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11119 TSPNTVPPISPPTATPTMPSTTPSTVSQTA-PATTPHTVPPT--LPyTVPPTSPNTVPSispttappttsstepPMLPYT 11195
Cdd:pfam17823 327 PSNTTLEPNTPKSVASTNLAVVTTTKAQAKePSASPVPVLHTsmIP-EVEATSPTTQPS---------------PLLPTQ 390
|
250 260
....*....|....*....|....*...
gi 1207107957 11196 ------MPPTALNTATAIAPPTAS--PT 11215
Cdd:pfam17823 391 gaagpgILLAPEQVATEATAGTASagPT 418
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
11088-11214 |
3.28e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 51.64 E-value: 3.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11088 PLTASPTMPSTAPSTVAPPTVLSTLPYTMPPTSPNTVPPISPPTATPtmPSTTPSTVSQTAPATTPHTVPPTLPYTVPPT 11167
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAAS--APAAPPAAAPPAPVAAPAAAAPAAAPAAAPA 443
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1207107957 11168 S--PNTVPSISPTTAPPTTSSTEPPMLPYTMPPTALNTATAIAPPTASP 11214
Cdd:PRK14951 444 AvaLAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
|
|
| KLF17_N |
cd21574 |
N-terminal domain of Kruppel-like factor 17; Kruppel-like factor 17 (KLF17), or Krueppel-like ... |
11091-11199 |
3.82e-05 |
|
N-terminal domain of Kruppel-like factor 17; Kruppel-like factor 17 (KLF17), or Krueppel-like factor 17, is a protein that, in humans, is encoded by the KLF17 gene and acts as a tumor suppressor. It negatively regulates epithelial-mesenchymal transition and metastasis in breast cancer. KLF17 is thought to be the human ortholog of the mouse gene, zinc finger protein 393 (Zfp393), although it has diverged significantly. KLF17 can regulate gene transcription from CACCC-box elements. It belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF17.
Pssm-ID: 410567 Cd Length: 286 Bit Score: 50.46 E-value: 3.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11091 ASPTMPSTAPSTvapPTVlsTLPYTMPPTSPNTVPPISPPTATPTMPsttpstvsqtapattpHTVPPTLPYTVPPTSPN 11170
Cdd:cd21574 122 GPQMMPLGEPNI---PGV--AMTFSGNLRMPPSGLPVSASSGIPMMS----------------HIRAPTMPYSGPPTVPS 180
|
90 100 110
....*....|....*....|....*....|
gi 1207107957 11171 TVPSISpttappttsstePPM-LPYTMPPT 11199
Cdd:cd21574 181 NRDSLT------------PKMlLAPTMPST 198
|
|
| Chi1 |
COG3469 |
Chitinase [Carbohydrate transport and metabolism]; |
11029-11217 |
4.58e-05 |
|
Chitinase [Carbohydrate transport and metabolism];
Pssm-ID: 442692 [Multi-domain] Cd Length: 534 Bit Score: 51.29 E-value: 4.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11029 YTMPPTFPNTVPPISPSTATPTMPSTTPFTVPPTTAPTAPPTLPYTMPPTALNTVTVIAPLTASPTMPSTAPSTVAPPTV 11108
Cdd:COG3469 22 LLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATLVATST 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11109 LSTLPYtmpPTSPNTVPPISPPTATPTMPSTTPSTVSQTAPATTPHTVPPTLPYTVPPTSPNTVPSISPTTAPPTTSSTE 11188
Cdd:COG3469 102 ASGANT---GTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSGTETATGGTTTTSTTTTTTSASTT 178
|
170 180
....*....|....*....|....*....
gi 1207107957 11189 PPMLPYTMPPTALNTATAIAPPTASPTMP 11217
Cdd:COG3469 179 PSATTTATATTASGATTPSATTTATTTGP 207
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
11028-11214 |
4.70e-05 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 51.08 E-value: 4.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11028 PYTM-----PPTFPNtvpPISPSTATPTMPSTTPFTVPPTTAPTAPPTLPYTMPPTALNTVTV-----IAPLTA------ 11091
Cdd:PLN03209 373 PYTAyedlkPPTSPI---PTPPSSSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEPAQVEAkktrpLSPYARyedlkp 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11092 ----SPTMPSTAPSTVAPPTVLSTLPYTMPPTSPNTVPPISPPTATPTMPSTTPSTV---SQTAPATTPHTVPPTLPYTV 11164
Cdd:PLN03209 450 ptspSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPPPANMRPLSPYAVYDDLkppTSPSPAAPVGKVAPSSTNEV 529
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1207107957 11165 PPTSPNTVPSisptTAPPTTSSTEP---PMLPYTM-----PPTAlntataiapPTASP 11214
Cdd:PLN03209 530 VKVGNSAPPT----ALADEQHHAQPkprPLSPYTMyedlkPPTS---------PTPSP 574
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
11083-11174 |
6.87e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 50.58 E-value: 6.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11083 VTVIAPLTASPTMPSTAPSTVAPPTvlSTLPYTMPPTSPNTVPPISPPTATPTMPSTTPSTVSqTAPATTPhtvPPTLPY 11162
Cdd:PRK14950 353 LAVIEALLVPVPAPQPAKPTAAAPS--PVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVP-PRPVAPP---VPHTPE 426
|
90
....*....|..
gi 1207107957 11163 TVPPTSPNTVPS 11174
Cdd:PRK14950 427 SAPKLTRAAIPV 438
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
11076-11169 |
9.65e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 50.19 E-value: 9.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11076 PPTALNTVTVIAPLTaSPTMPSTAPSTVAPPTVLSTLPYTMPPTSPNTVPPISPPTATPTMPSTTPStvsqtAPATTPHT 11155
Cdd:PRK14950 362 PVPAPQPAKPTAAAP-SPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPES-----APKLTRAA 435
|
90
....*....|....*
gi 1207107957 11156 VP-PTLPYTVPPTSP 11169
Cdd:PRK14950 436 IPvDEKPKYTPPAPP 450
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
11093-11167 |
9.78e-05 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 49.57 E-value: 9.78e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1207107957 11093 PTMPSTAPStVAPPTVLstLPYTMPPTSPNTVPP--ISPPTATPTMPSTTPSTVSQTAPATTPHTVPPTLPYTVPPT 11167
Cdd:PHA03291 188 PALPLSAPR-LGPADVF--VPATPRPTPRTTASPetTPTPSTTTSPPSTTIPAPSTTIAAPQAGTTPEAEGTPAPPT 261
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
11090-11430 |
1.15e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 50.07 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11090 TASPTMPSTAPSTVAPPTVL-------STLPYTMPPTSPNTVPPISP-PTATPTMPSTTPSTVSQTAP--ATTPHTVPPT 11159
Cdd:PHA03378 523 TLLPPSPPQPRAGRRAPCVYtedldieSDEPASTEPVHDQLLPAPGLgPLQIQPLTSPTTSQLASSAPsyAQTPWPVPHP 602
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11160 LPYTVPPTSPNTVPSiSPTTAPPTTSSTEPPMLPYTMPPTALNTA---TAIAPPTASPTmpsitpstvpptaPPTTAPTV 11236
Cdd:PHA03378 603 SQTPEPPTTQSHIPE-TSAPRQWPMPLRPIPMRPLRMQPITFNVLvfpTPHQPPQVEIT-------------PYKPTWTQ 668
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11237 PPTLPYTVPPTSPNTVPPIAPTTAPPTTsstvPPTLPYTMPPTAlntatviAPPTSSPTMASTTLSMvaptappttppta 11316
Cdd:PHA03378 669 IGHIPYQPSPTGANTMLPIQWAPGTMQP----PPRAPTPMRPPA-------APPGRAQRPAAATGRA------------- 724
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11317 pptlpytMPPTAlnTATAIAPPTASPTMPSITPSTVAATAPPTTLPYSMPPTAkntvppiapptATptlpsttpstvPPT 11396
Cdd:PHA03378 725 -------RPPAA--APGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPA-----------AA-----------PGA 773
|
330 340 350
....*....|....*....|....*....|....*
gi 1207107957 11397 ATTTTLSTVPPTlPSTTPSTVP-PTAPPTVSPTAV 11430
Cdd:PHA03378 774 PTPQPPPQAPPA-PQQRPRGAPtPQPPPQAGPTSM 807
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
11077-11438 |
1.33e-04 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 49.57 E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11077 PTALNTVTVIAPLTASpTMPsTAPSTVAPPTVLSTLPYTmPPTSPNTvpPISPPTATPTMPSTTPSTVSQTAPAT----T 11152
Cdd:pfam17823 48 PRADNKSSEQ*NFCAA-TAA-PAPVTLTKGTSAAHLNST-EVTAEHT--PHGTDLSEPATREGAADGAASRALAAaassS 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11153 PHTVPPTLPYTV--PPTSPNTVPSispttappttssTEPPMLPYTMPPTAlNTATAIAPPTASP---TMPSITPSTVPPT 11227
Cdd:pfam17823 123 PSSAAQSLPAAIaaLPSEAFSAPR------------AAACRANASAAPRA-AIAAASAPHAASPaprTAASSTTAASSTT 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11228 APPTTAPTVPPTLPYTVPPTSPNTVPPIApttappttsstvpptlpyTMPPtALNTATViAPPTSSPtMASTTLSMVAPT 11307
Cdd:pfam17823 190 AASSAPTTAASSAPATLTPARGISTAATA------------------TGHP-AAGTALA-AVGNSSP-AAGTVTAAVGTV 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11308 APPTTPPTAPPTLPYTMPPTALNTATAIAP-PTASPTMPSitpSTVAATAPPTTLPYSMPPTAKNTVPPIAPPTATPTlp 11386
Cdd:pfam17823 249 TPAALATLAAAAGTVASAAGTINMGDPHARrLSPAKHMPS---DTMARNPAAPMGAQAQGPIIQVSTDQPVHNTAGEP-- 323
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1207107957 11387 stTPSTVPPTATTTTLSTVPPTLPSTTPSTVPPTAPPTVSPTAVCEETLIDE 11438
Cdd:pfam17823 324 --TPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSMIPE 373
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
11027-11213 |
1.56e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 49.68 E-value: 1.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11027 LPYTMPPTFPNTVPPIS--PSTATPtmpsttpftvppttaptapptlpytmPPTalntvtviAPLTASPtmPSTAPSTVA 11104
Cdd:PHA03378 672 IPYQPSPTGANTMLPIQwaPGTMQP--------------------------PPR--------APTPMRP--PAAPPGRAQ 715
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11105 PPTVlSTLPYTMPPTSPNTV-PPISPPTATPTmPSTTPSTVSQTAPATTPHTVPPTLPYTVPPTSPNTVPSIspttappt 11183
Cdd:PHA03378 716 RPAA-ATGRARPPAAAPGRArPPAAAPGRARP-PAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPA-------- 785
|
170 180 190
....*....|....*....|....*....|.
gi 1207107957 11184 tSSTEPPMLPYTM-PPTALNTATAIAPPTAS 11213
Cdd:PHA03378 786 -PQQRPRGAPTPQpPPQAGPTSMQLMPRAAP 815
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
11086-11369 |
2.83e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 48.91 E-value: 2.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11086 IAPLTASPT--MPSTAPSTVAPPTvLSTLPYTMP--PTSPNTVPPISPPTATPTMPSTTPSTVSQTAPATTPHTVPPTlP 11161
Cdd:PHA03378 574 IQPLTSPTTsqLASSAPSYAQTPW-PVPHPSQTPepPTTQSHIPETSAPRQWPMPLRPIPMRPLRMQPITFNVLVFPT-P 651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11162 YTVPPTSPNTVPSispttappttSSTEPPMLPYTMPPTALNTA-------TAIAPPTASPTmpsitpstvpptappttap 11234
Cdd:PHA03378 652 HQPPQVEITPYKP----------TWTQIGHIPYQPSPTGANTMlpiqwapGTMQPPPRAPT------------------- 702
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11235 tvpptlpytvpPTSPNTVPPIAPTTappttsstvPPTLPYTMPPTAlNTATVIAPPTSSPTMASTTlsmvaptAPPTTPP 11314
Cdd:PHA03378 703 -----------PMRPPAAPPGRAQR---------PAAATGRARPPA-AAPGRARPPAAAPGRARPP-------AAAPGRA 754
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1207107957 11315 TAPPTLPYTMPP--TALNTATAIAPPTASPT---MPSITPstvAATAPPTTLPYSM---PPTA 11369
Cdd:PHA03378 755 RPPAAAPGRARPpaAAPGAPTPQPPPQAPPApqqRPRGAP---TPQPPPQAGPTSMqlmPRAA 814
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
11083-11360 |
3.09e-04 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 48.76 E-value: 3.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11083 VTVIAPLTASPTMPSTAPSTVAPPTVLSTLpYTMPPTSPNTVPPI-----SPPTATPTMPSTTPSTVSQTAPATTPHTVP 11157
Cdd:pfam05109 391 ITVSGLGTAPKTLIITRTATNATTTTHKVI-FSKAPESTTTSPTLnttgfAAPNTTTGLPSSTHVPTNLTAPASTGPTVS 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11158 ------PTLPYTVPPTSPNTvPSisPTTAPPTTSSTEPPMlpyTMPPTALNTATAIA-PPTASPTMPSitPSTVPPTAPP 11230
Cdd:pfam05109 470 tadvtsPTPAGTTSGASPVT-PS--PSPRDNGTESKAPDM---TSPTSAVTTPTPNAtSPTPAVTTPT--PNATSPTLGK 541
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11231 TTaptvpptlpytvpPTSPNTVPPIAPTTAPPTTSSTVP----PTLPYTMPPTALNTATviaPPTSSPTMASTTLSMVAP 11306
Cdd:pfam05109 542 TS-------------PTSAVTTPTPNATSPTPAVTTPTPnatiPTLGKTSPTSAVTTPT---PNATSPTVGETSPQANTT 605
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1207107957 11307 TAPPTTPPTAPPTlpyTMPPTALNTATAIAP---PTASPTMPSITPSTVAATAPPTT 11360
Cdd:pfam05109 606 NHTLGGTSSTPVV---TSPPKNATSAVTTGQhniTSSSTSSMSLRPSSISETLSPST 659
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
11085-11153 |
6.76e-04 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 46.37 E-value: 6.76e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11085 VIAPLTASPTMPSTAPS-TVAPPTVLSTLPYTMPPTSPNTVPPISPPTATPTMPSTTPSTVSQTAPATTP 11153
Cdd:PLN02983 134 VIRKKEALPQPPPPAPVvMMQPPPPHAMPPASPPAAQPAPSAPASSPPPTPASPPPAKAPKSSHPPLKSP 203
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
11079-11172 |
6.81e-04 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 47.30 E-value: 6.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11079 ALNTVTVIAPLTASPTMPSTAPSTVAPPTVLSTL-PYTMPPTSPNTVPPISPPTATPTMPS--TTPSTVSQTAPATTPHT 11155
Cdd:PHA03369 348 LKTASLTAPSRVLAAAAKVAVIAAPQTHTGPADRqRPQRPDGIPYSVPARSPMTAYPPVPQfcGDPGLVSPYNPQSPGTS 427
|
90
....*....|....*..
gi 1207107957 11156 VPPTLPYTVPPTSPNTV 11172
Cdd:PHA03369 428 YGPEPVGPVPPQPTNPY 444
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
11028-11189 |
7.83e-04 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 46.39 E-value: 7.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11028 PYTMPPTFPnTVPPISPSTATPTmpsttpftvppttaptapptlpyTMPPTALNTVTVIAPLTASPtmPSTAPsTVAPPT 11107
Cdd:PHA02682 76 PSGQSPLAP-SPACAAPAPACPA-----------------------CAPAAPAPAVTCPAPAPACP--PATAP-TCPPPA 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11108 VLSTLPYTMPPTSPNT--VPPISP-PTATPtMPSTTPSTVSQTAPattphtvPPTLPYTVPPTSpNTVPSispttappTT 11184
Cdd:PHA02682 129 VCPAPARPAPACPPSTrqCPPAPPlPTPKP-APAAKPIFLHNQLP-------PPDYPAASCPTI-ETAPA--------AS 191
|
....*
gi 1207107957 11185 SSTEP 11189
Cdd:PHA02682 192 PVLEP 196
|
|
| PRK13042 |
PRK13042 |
superantigen-like protein SSL4; Reviewed; |
11083-11171 |
1.30e-03 |
|
superantigen-like protein SSL4; Reviewed;
Pssm-ID: 183854 [Multi-domain] Cd Length: 291 Bit Score: 45.78 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11083 VTVIAPLTASPTMPSTAPSTVAPPTVLSTLPYTMPPTSPNTVPPISPPTATPTMPS-TTPSTVSQTAPATTPHTVPPTLP 11161
Cdd:PRK13042 3 ITTIAKTSLALGLLTTGVITTTTQAANATTPSSTKVEAPQSTPPSTKVEAPQSKPNaTTPPSTKVEAPQQTPNATTPSST 82
|
90
....*....|
gi 1207107957 11162 YTVPPTSPNT 11171
Cdd:PRK13042 83 KVETPQSPTT 92
|
|
| TALPID3 |
pfam15324 |
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ... |
11081-11174 |
1.38e-03 |
|
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.
Pssm-ID: 434634 [Multi-domain] Cd Length: 1288 Bit Score: 46.80 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11081 NTVTVIAPL-TASPTMPSTAPSTVAPPTVLSTlPYTMPPTSP---NTVPPISPPTATPTMPSTTPSTVSQTAPATTPHTV 11156
Cdd:pfam15324 980 KETLLPTPVpTPQPTPPCSPPSPLKEPSPVKT-PDSSPCVSEhdfFPVKEIPPEKGADTGPAVSLVITPTVTPIATPPPA 1058
|
90
....*....|....*....
gi 1207107957 11157 P-PTLPytVPPTSPNTVPS 11174
Cdd:pfam15324 1059 AtPTPP--LSENSIDKLKS 1075
|
|
| KLF3_N |
cd21577 |
N-terminal domain of Kruppel-like factor 3; Kruppel-like factor 3 (KLF3; also called ... |
11117-11198 |
2.07e-03 |
|
N-terminal domain of Kruppel-like factor 3; Kruppel-like factor 3 (KLF3; also called Krueppel-like factor 3 and originally called Basic Kruppel-like Factor/BKLF), was the third member of the KLF family of zinc finger transcription factors to be discovered. KLF3 possesses a wide range of biological impacts on regulating apoptosis, differentiation, and proliferation in various tissues during the entire progression process. It has been proposed as a tumor suppressor in colorectal cancer. It appears to function predominantly as a repressor of transcription, turning genes off by recruiting the C-terminal Binding Protein co-repressors CtBP1 and CtBP2. CtBP docks onto a short motif (residues 61-65) in the N-terminus of KLF3, through the Proline-X-Aspartate-Leucine-Serine (PXDLS) motif. CtBP in turn recruits histone modifying enzymes to alter chromatin and repress gene expression. KLF3 belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF3.
Pssm-ID: 410554 [Multi-domain] Cd Length: 214 Bit Score: 44.26 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11117 PPTSPNTVPPISPPTATPTMPSTTPSTVSQTAPATTPHTVPPTLPYTVPPTSPNTVPSISPTTAPPTTSStePPM---LP 11193
Cdd:cd21577 32 PPSSSSSSSSSSSSSSSPSSRASPPSPYSKSSPPSPPQQRPLSPPLSLPPPVAPPPLSPGSVPGGLPVIS--PVMvqpVP 109
|
....*
gi 1207107957 11194 YTMPP 11198
Cdd:cd21577 110 VLYPP 114
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
11043-11217 |
2.60e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 45.64 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11043 SPSTATPTMPSTTPFTVPPTTAPTAPPTLPYTMPPTALNTVTVIAPLTASPTMPSTAPSTVAP--------PTVLSTLPY 11114
Cdd:PRK12323 373 GPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAarqasargPGGAPAPAP 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11115 TMPPTSPNTVPPISPPTATPTMPSTTPSTVSQTA--PATTPHTVPP--TLPYTVPptspntVPSISPTTAPPTTSSTEPP 11190
Cdd:PRK12323 453 APAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAaaPAPADDDPPPweELPPEFA------SPAPAQPDAAPAGWVAESI 526
|
170 180
....*....|....*....|....*..
gi 1207107957 11191 MLPYTMPPTAlNTATAIAPPTASPTMP 11217
Cdd:PRK12323 527 PDPATADPDD-AFETLAPAPAAAPAPR 552
|
|
| Chi1 |
COG3469 |
Chitinase [Carbohydrate transport and metabolism]; |
11076-11174 |
3.06e-03 |
|
Chitinase [Carbohydrate transport and metabolism];
Pssm-ID: 442692 [Multi-domain] Cd Length: 534 Bit Score: 45.13 E-value: 3.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11076 PPTALNTVTVIAPLTASPTMPSTAPSTVAPPTVLSTLPYTMPPTSPNTVPPISPPTATPTMPSTTPSTVSQTAPATTPHT 11155
Cdd:COG3469 113 TTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSGTETATGGTTTTSTTTTTTSASTTPSATTTATATTASG 192
|
90
....*....|....*....
gi 1207107957 11156 VPPTLPYTVPPTSPNTVPS 11174
Cdd:COG3469 193 ATTPSATTTATTTGPPTPG 211
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
11076-11214 |
3.89e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 45.31 E-value: 3.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11076 PPTALNTvtviapLTASPTMPSTAPstvapptvlstLPYTMPPTSPNTVPPISPPTATPTMPSTTPSTvsqtaPATTPHT 11155
Cdd:PHA03247 361 PPSSLED------LSAGRHHPKRAS-----------LPTRKRRSARHAATPFARGPGGDDQTRPAAPV-----PASVPTP 418
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1207107957 11156 VPPTLPYTVPPTSPNTVPSispttaPPTTSSTEPPMLPYTMPPTALNTATAIAPPTASP 11214
Cdd:PHA03247 419 APTPVPASAPPPPATPLPS------AEPGSDDGPAPPPERQPPAPATEPAPDDPDDATR 471
|
|
| half-pint |
TIGR01645 |
poly-U binding splicing factor, half-pint family; The proteins represented by this model ... |
11079-11219 |
3.95e-03 |
|
poly-U binding splicing factor, half-pint family; The proteins represented by this model contain three RNA recognition motifs (rrm: pfam00076) and have been characterized as poly-pyrimidine tract binding proteins associated with RNA splicing factors. In the case of PUF60 (GP|6176532), in complex with p54, and in the presence of U2AF, facilitates association of U2 snRNP with pre-mRNA.
Pssm-ID: 130706 [Multi-domain] Cd Length: 612 Bit Score: 45.06 E-value: 3.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11079 ALNTVTVIAPLTASPTMPSTA-------PSTVAPPTVLSTLPYTMPPTSPNTVPPISPPTATPTMPSTTPstvsqtapat 11151
Cdd:TIGR01645 317 AVAGAAVLGPRAQSPATPSSSlptdignKAVVSSAKKEAEEVPPLPQAAPAVVKPGPMEIPTPVPPPGLA---------- 386
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1207107957 11152 TPHTVPPtlPYTVPPTSPNtvPSISPTTAPPTTSSTEPPMLPYTMPPTALNTATAIAPPTASPTMPSI 11219
Cdd:TIGR01645 387 IPSLVAP--PGLVAPTEIN--PSFLASPRKKMKREKLPVTFGALDDTLAWKEPSKEDQTSEDGKMLAI 450
|
|
| PLN02217 |
PLN02217 |
probable pectinesterase/pectinesterase inhibitor |
11077-11171 |
4.07e-03 |
|
probable pectinesterase/pectinesterase inhibitor
Pssm-ID: 215130 [Multi-domain] Cd Length: 670 Bit Score: 45.08 E-value: 4.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11077 PTALNTVTVIAPLTASPTMPSTAPSTVAPPTvlstlpyTMPPTSPNTVPPISPPTATPtmPSTTPSTVSQTAPATTPHT- 11155
Cdd:PLN02217 566 PGSTNSTPTGSAASSNTTFSSDSPSTVVAPS-------TSPPAGHLGSPPATPSKIVS--PSTSPPASHLGSPSTTPSSp 636
|
90
....*....|....*.
gi 1207107957 11156 VPPTLPYTVPPTSPNT 11171
Cdd:PLN02217 637 ESSIKVASTETASPES 652
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
11095-11215 |
4.10e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 44.71 E-value: 4.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11095 MPSTAPSTVAPPTVLSTLPYTMPPTSPNTVPPISPPTATPTMPSTTPSTVSQTAPATTPHTVPPTLPYT--VPPTSPNTV 11172
Cdd:PRK12799 295 THGTVPVAAVTPSSAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTvaLPAAEPVNM 374
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1207107957 11173 PSISPTTAPPTTSSTEPPMLPYTMPPTALNTATAI-APPtaSPT 11215
Cdd:PRK12799 375 QPQPMSTTETQQSSTGNITSTANGPTTSLPAAPASnIPV--SPT 416
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
11096-11215 |
5.11e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 44.38 E-value: 5.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11096 PSTAPSTVAPPTVLSTLPYTMPPTSPNtvppispPTATPTMPSTTPSTvSQTAPATTPHTVPPTLPYTVPPTSPNTVPSI 11175
Cdd:PRK14971 371 GGRGPKQHIKPVFTQPAAAPQPSAAAA-------ASPSPSQSSAAAQP-SAPQSATQPAGTPPTVSVDPPAAVPVNPPST 442
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1207107957 11176 SPTTAPPTTSSTEPPMLPYTMPPTALNTATAIAPPTASPT 11215
Cdd:PRK14971 443 APQAVRPAQFKEEKKIPVSKVSSLGPSTLRPIQEKAEQAT 482
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
11087-11422 |
5.64e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 44.53 E-value: 5.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11087 APLTASPTMPSTAPSTVAPPtvlstlPYTMPPTSPNTVPPISPPTATPTMPSttpstvsQTAPATTPHTVP-PTLPYTV- 11164
Cdd:PLN03209 311 APLTPMEELLAKIPSQRVPP------KESDAADGPKPVPTKPVTPEAPSPPI-------EEEPPQPKAVVPrPLSPYTAy 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11165 ----PPTSPNTVPSispttappttssteppmlpyTMPPTALNTATAIAPPTASPTMPSITPSTVPPTAPPTTAPTVpptl 11240
Cdd:PLN03209 378 edlkPPTSPIPTPP--------------------SSSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEPAQVEAK---- 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11241 pyTVPPTSPNTVPPIAPttappttsstvPPTLPYTMPPTAlntatvIAPPTSSPTMASTTlsmvaptappttpptapptl 11320
Cdd:PLN03209 434 --KTRPLSPYARYEDLK-----------PPTSPSPTAPTG------VSPSVSSTSSVPAV-------------------- 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11321 PYTMPPTALNTATAIAPPTASPtmpsITPSTVAATAPPTTLPYSMPPTAKntvppiaPPTATPTLPSTTPSTVPPTATTT 11400
Cdd:PLN03209 475 PDTAPATAATDAAAPPPANMRP----LSPYAVYDDLKPPTSPSPAAPVGK-------VAPSSTNEVVKVGNSAPPTALAD 543
|
330 340
....*....|....*....|....*..
gi 1207107957 11401 TLSTVPPTLPSTTPSTV-----PPTAP 11422
Cdd:PLN03209 544 EQHHAQPKPRPLSPYTMyedlkPPTSP 570
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
11076-11173 |
5.72e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 44.32 E-value: 5.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11076 PPTALNTVTVIAPltasptmPSTAPSTVAPPTVLSTLPYTMPPTSPNTVPPISPPTATPTMPSttPSTVSQTAPATTPHT 11155
Cdd:PRK14951 395 AQAAAAPAPAAAP-------AAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPA--PPAQAAPETVAIPVR 465
|
90
....*....|....*...
gi 1207107957 11156 VPPTLPYTVPPTSPNTVP 11173
Cdd:PRK14951 466 VAPEPAVASAAPAPAAAP 483
|
|
| MISS |
pfam15822 |
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic ... |
10857-11217 |
5.76e-03 |
|
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic MAPK-interacting and spindle-stabilising protein-like proteins. MISS is rich in prolines and has four potential MAPK-phosphorylation sites, a MAPK-docking site, a PEST sequence (PEST motif) and a bipartite nuclear localization signal. The endogenous protein accumulates during mouse meiotic maturation and is found as discrete dots on the MII spindle. MISS is the first example of a physiological MAPK-substrate that is stabilized in MII that specifically regulates MII spindle integrity during the CSF arrest.
Pssm-ID: 318115 [Multi-domain] Cd Length: 238 Bit Score: 43.05 E-value: 5.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10857 PTASPTMPSTTLSTvaptappttpptvpstLPytmPPTSSNTVPPISPPTAT-PTMpstvpptappttpptapptlpytm 10935
Cdd:pfam15822 35 PWNNPSAPPAVPSG----------------LP---PSTAPSTVPFGPAPTGMyPSI------------------------ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10936 PPTSPNTAPPiasptatptmpsttpttipptappttpptvpptlpYTMPPTALntataiatptaSPTMPSTtlstvapta 11015
Cdd:pfam15822 72 PLTGPSPGPP-----------------------------------APFPPSGP-----------SCPPPGG--------- 96
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11016 ppttpptvpstlPYTmPPTFPNTVPPisPSTATPTMPSTTpftvppttaptapptlpytMPptalntvtviAPLTAsPTM 11095
Cdd:pfam15822 97 ------------PYP-APTVPGPGPI--GPYPTPNMPFPE-------------------LP----------RPYGA-PTD 131
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11096 PStAPSTVAPPTVLSTLPYTmpptspntvPPISPPTATPTMPSTTPSTVSQTAPATTPHTVPPtLPY-TVPPTS---PNT 11171
Cdd:pfam15822 132 PA-AAAPSGPWGSMSSGPWA---------PGMGGQYPAPNMPYPSPGPYPAVPPPQSPGAAPP-VPWgTVPPGPwgpPAP 200
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1207107957 11172 VPsispttappttsstePPMLPYTMP---PTALNTATAIAPPTASPTMP 11217
Cdd:pfam15822 201 YP---------------DPTGSYPMPglyPTPNNPFQVPSGPSGAPPMP 234
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
11090-11166 |
5.80e-03 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 43.86 E-value: 5.80e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1207107957 11090 TASPTMPSTAPSTVAPPTVLSTLPYTMPPTSPNTVPPISPPTATPTMPSTTPSTVSQTAPATTPHTVPPTLPYTVPP 11166
Cdd:PRK10856 160 QSVPLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAP 236
|
|
| PRK11901 |
PRK11901 |
hypothetical protein; Reviewed |
11087-11219 |
6.23e-03 |
|
hypothetical protein; Reviewed
Pssm-ID: 237015 [Multi-domain] Cd Length: 327 Bit Score: 43.52 E-value: 6.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11087 APLTASPTMPSTAPSTVAPPTvlSTLPYTMPPTSPNtvPPISPPTATPT------MPSTTPSTVSQ--------TAPATT 11152
Cdd:PRK11901 94 SPSAANNTSDGHDASGVKNTA--PPQDISAPPISPT--PTQAAPPQTPNgqqrieLPGNISDALSQqqgqvnaaSQNAQG 169
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207107957 11153 PHTVPPTLPYTVPPTSPNTVPSISPT--TAPPTTSSTEPPMLPYTMPPTALNTATAIAPPTASPTMPSI 11219
Cdd:PRK11901 170 NTSTLPTAPATVAPSKGAKVPATAEThpTPPQKPATKKPAVNHHKTATVAVPPATSGKPKSGAASARAL 238
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
11085-11209 |
6.38e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 44.32 E-value: 6.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11085 VIAPLTASPTMPSTAPSTVAP--PTVLSTLPYTMPPTSpnTVPPISPPTATPTMPSTTPSTVSQTAPattphtvPPTLPY 11162
Cdd:PRK14951 373 AAPAEKKTPARPEAAAPAAAPvaQAAAAPAPAAAPAAA--ASAPAAPPAAAPPAPVAAPAAAAPAAA-------PAAAPA 443
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1207107957 11163 TVPPTSPNTVPSISPTTAPPTTSSTEPPMLPYTMPPTALNTATAIAP 11209
Cdd:PRK14951 444 AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTP 490
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
10754-11172 |
8.05e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 43.80 E-value: 8.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10754 PNTAPNTAPPIASPTATPTMLSTTPITVPPTAPPTTVPPTVPYTMPPTAL-NTATAIAPPTASPTMSSTTLSTVAPPTTP 10832
Cdd:pfam17823 100 PATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAPRAAAcRANASAAPRAAIAAASAPHAASPAPRTAA 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10833 PTAPPTLPYTMPPTALNTATVIAPPTASPTMPSTTLSTVAPTAPPTtpptvpstlpytmppTSSNTVPPISPPTATPTMP 10912
Cdd:pfam17823 180 SSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHPAAG---------------TALAAVGNSSPAAGTVTAA 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10913 STVPPTAPPTTPPTAPPTLPYTmpPTSPNTAPPIASPTATptmpsttpttipptappttpptvpptlpytmpptalntat 10992
Cdd:pfam17823 245 VGTVTPAALATLAAAAGTVASA--AGTINMGDPHARRLSP---------------------------------------- 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 10993 aiatptaSPTMPSTTLSTVAPTAPPTTPPTVPSTLPYTMPPTfpNTVPPISPSTATPTMPSTTPFTVPPTTAPTAPPTLP 11072
Cdd:pfam17823 283 -------AKHMPSDTMARNPAAPMGAQAQGPIIQVSTDQPVH--NTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTKA 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207107957 11073 YTMPPTAlNTVTVIaPLTASPTMPSTAPSTVApptvlSTLPYTMPPTSPNTvpPISPPT----ATPTMPSTTPSTVSQTA 11148
Cdd:pfam17823 354 QAKEPSA-SPVPVL-HTSMIPEVEATSPTTQP-----SPLLPTQGAAGPGI--LLAPEQvateATAGTASAGPTPRSSGD 424
|
410 420 430
....*....|....*....|....*....|
gi 1207107957 11149 PAT------TPHTVPPTLPYTVPPTSPNTV 11172
Cdd:pfam17823 425 PKTlamascQLSTQGQYLVVTTDPLTPALV 454
|
|
| |
